quadazocine has been researched along with naloxone in 27 studies
| Studies (quadazocine) | Trials (quadazocine) | Recent Studies (post-2010) (quadazocine) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 81 | 0 | 0 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | quadazocine (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (85.19) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Flitstein, A; Oppenheimer, E; Sarne, Y | 1 |
| Cagampang, FR; Maeda, K | 1 |
| Hahn, EF; Howard, DH; Levison, JA; Pasternak, GW; Paul, D; Pick, CG | 1 |
| France, CP; Morse, WH | 1 |
| Condon, RE; Szurszewski, JH; Telford, GL | 1 |
| Skarphedinsson, JO; Thorén, P | 1 |
| Dodson, BA; Miller, KW | 1 |
| Bradford, HF; Crowder, JM; White, EJ | 1 |
| Adler, MW; Geller, EB; Tiseo, PJ | 1 |
| George, R; Pechnick, R; Poland, RE | 1 |
| Portoghese, PS; Takemori, AE | 1 |
| Carter, R; Cooper, SJ; Jackson, A; Morgan, R | 1 |
| Barber, DJ; Barbour-McMullen, J; Cooper, SJ | 1 |
| Chandra, A; Diliberto, EJ; Dixon, WR; Holaday, JW; Lewis, JW; Long, JB; Tortella, FC; Unsworth, CD; Viveros, OH; Way, EL | 1 |
| Faden, AI | 1 |
| DeFelice, AF; Lape, HE; Michne, WF; Norton, JD | 1 |
| Gmerek, DE; Woods, JH | 1 |
| France, CP; Woods, JH | 1 |
| Huidobro-Toro, JP; Parada, S | 1 |
| Huidobro-Toro, JP; Way, EL; Yoshimura, K | 1 |
| Billington, CJ; Gosnell, BA; Levine, AS; Morley, JE | 1 |
| Curtis, MT; Lefer, AM | 1 |
| Hynes, MD; Leander, JD | 1 |
| Amir, S | 1 |
| Michne, WF; Pierson, AK; Ward, SJ | 1 |
| Bermudez-Rattoni, F; Cruz-Morales, S; Reid, LD | 1 |
27 other study(ies) available for quadazocine and naloxone
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Anti-arrhythmic activities of opioid agonists and antagonists and their stereoisomers.
Topics: Animals; Anti-Arrhythmia Agents; Azocines; Levorphanol; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Stereoisomerism | 1991 |
Effects of intracerebroventricular administration of opiate receptor antagonists on the suppressed pulsatile LH release during acute fasting in ovariectomized estradiol-treated rats.
Topics: Animals; Azocines; Enkephalin, Leucine; Estradiol; Fasting; Female; Injections, Intraventricular; Luteinizing Hormone; Naloxone; Narcotic Antagonists; Ovariectomy; Periodicity; Rats; Rats, Inbred Strains; Receptors, Opioid | 1991 |
Naloxone benzoylhydrazone (NalBzoH) analgesia.
Topics: Analgesia; Analgesics; Animals; Azocines; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Naloxone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Pharmacological characterization of supersensitivity to naltrexone in squirrel monkeys.
Topics: Animals; Azocines; Behavior, Animal; Benzomorphans; Diprenorphine; Drug Administration Schedule; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Saimiri | 1989 |
Opioid receptors and the initiation of migrating myoelectric complexes in dogs.
Topics: Animals; Azocines; Bethanechol; Bethanechol Compounds; Digestive System; Digestive System Physiological Phenomena; Dogs; Duodenum; Electrophysiology; Food; Gastrointestinal Motility; Ileum; Morphine; Motilin; Naloxone; Narcotic Antagonists; Receptors, Opioid; Stereoisomerism; Stomach | 1989 |
Endorphin mechanisms are responsible for the beneficial effects of opioid antagonists on cerebral function during relative cerebral ischaemia in rats.
Topics: Animals; Azocines; Bicuculline; Brain; Brain Ischemia; Evoked Potentials, Somatosensory; Hemodynamics; Male; Naloxone; Rats; Rats, Inbred SHR; Receptors, Opioid; Thyrotropin-Releasing Hormone | 1988 |
Evidence for a dual mechanism in the anesthetic action of an opioid peptide.
Topics: 1-Octanol; Analgesics, Opioid; Anesthetics; Animals; Atmospheric Pressure; Azocines; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Lipids; Naloxone; Narcotic Antagonists; Octanols; Postural Balance; Rana pipiens; Receptors, Opioid; Reflex; Solubility; Time Factors | 1985 |
Inhibitory actions of opioid compounds on calcium fluxes and neurotransmitter release from mammalian cerebral cortical slices.
Topics: Amino Acids; Animals; Azocines; Calcium; Calcium Radioisotopes; Cerebral Cortex; Endorphins; In Vitro Techniques; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Neurotransmitter Agents; Potassium; Rats; Stereoisomerism | 1986 |
Antinociceptive action of intracerebroventricularly administered dynorphin and other opioid peptides in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Azocines; Cold Temperature; Drug Interactions; Dynorphins; Enkephalins; Injections, Intraventricular; Male; Naloxone; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid | 1988 |
Identification of multiple opiate receptors through neuroendocrine responses. II. Antagonism of mu, kappa and sigma agonists by naloxone and WIN 44,441-3.
Topics: Animals; Azocines; Corticosterone; Cyclazocine; Drug Interactions; Ethylketocyclazocine; Growth Hormone; Luteinizing Hormone; Male; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
TENA, a selective kappa opioid receptor antagonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1985 |
Evidence for opiate receptor involvement in the consumption of a high palatability diet in nondeprived rats.
Topics: Animals; Appetite Depressants; Azocines; Diet; Feeding Behavior; Female; Male; Naloxone; Obesity; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sex Factors | 1985 |
Selective attenuation of sweetened milk consumption by opiate receptor antagonists in male and female rats of the Roman strains.
Topics: Animals; Appetite Depressants; Azocines; Benzomorphans; Diprenorphine; Enkephalin, Leucine; Feeding Behavior; Female; Male; Naloxone; Narcotic Antagonists; Rats; Receptors, Opioid; Sex Factors; Species Specificity | 1985 |
Multiple opiate receptors: functional implications.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Azocines; Behavior, Animal; Binding Sites; Blood Pressure; Clonidine; Corticosterone; Enkephalins; Naloxone; Receptors, Opioid; Stress, Physiological; Sympathetic Nervous System | 1985 |
New pharmacologic approaches to spinal cord injury: opiate antagonists and thyrotropin-releasing hormone.
Topics: Animals; Azocines; Cats; Endorphins; Enkephalin, Leucine; Humans; Naloxone; Narcotic Antagonists; Rabbits; Receptors, Opioid; Spinal Cord Injuries; Thiazolidines; Thyrotropin-Releasing Hormone | 1985 |
Effect of Win 44441-3 and naloxone on endotoxin-induced hypotensive shock in anesthetized hypertensive rats.
Topics: Animals; Azocines; Disease Models, Animal; Escherichia coli; Lipopolysaccharides; Male; Naloxone; Rats; Rats, Inbred SHR; Shock, Septic | 1985 |
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1985 |
Antagonistic and rate-suppressing effects of opioid antagonists in the pigeon.
Topics: Animals; Azocines; Benzomorphans; Buprenorphine; Columbidae; Conditioning, Operant; Diprenorphine; Dose-Response Relationship, Drug; Morphine; Naloxone; Naltrexone; Narcotic Antagonists | 1985 |
Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Female; Injections, Intraperitoneal; Morphinans; Morphine; Naloxone; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Water-Electrolyte Balance | 1984 |
Potency of three opiate antagonists to reverse the inhibitory activity of dynorphin, enkephalins and opioid-like alkaloids on the guinea pig ileum.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Dynorphins; Endorphins; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Derivatives; Muscle, Smooth; Naloxone; Narcotic Antagonists | 1982 |
Which opioid receptor mechanism modulates feeding?
Topics: Animals; Azocines; Diprenorphine; Dynorphins; Endorphins; Feeding Behavior; Humans; Mice; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1984 |
Beneficial action of a new opiate antagonist (Win 44,441-3) in hemorrhagic shock.
Topics: Animals; Azocines; Benzomorphans; Blood Pressure; Cathepsin D; Cathepsins; Cats; Liver; Male; Morphinans; Myocardial Depressant Factor; Naloxone; Narcotic Antagonists; Receptors, Opioid; Shock, Hemorrhagic; Time Factors | 1982 |
Opioid antagonists and drinking: evidence of kappa-receptor involvement.
Topics: Animals; Azocines; Benzomorphans; Drinking; Male; Naloxone; Narcotic Antagonists; Rats; Receptors, Opioid | 1983 |
Morphine exacerbates anaphylactic shock in mice by stimulating central opiate receptors.
Topics: Anaphylaxis; Animals; Azocines; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1983 |
Multiple opioid receptor profile in vitro and activity in vivo of the potent opioid antagonist Win 44,441-3.
Topics: Animals; Azocines; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Naloxone; Narcotic Antagonists; Phenazocine; Receptors, Opioid; Vas Deferens | 1983 |
Addictive agents and intracranial stimulation (ICS): novel antagonists and agonists of morphine and pressing for ICS.
Topics: Animals; Azocines; Brain; Electric Stimulation; Hypothalamic Area, Lateral; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Self Stimulation | 1983 |