quadazocine has been researched along with morphine in 20 studies
| Studies (quadazocine) | Trials (quadazocine) | Recent Studies (post-2010) (quadazocine) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 81 | 0 | 0 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | quadazocine (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Flitstein, A; Oppenheimer, E; Sarne, Y | 1 |
| France, CP; Morse, WH | 1 |
| Condon, RE; Szurszewski, JH; Telford, GL | 1 |
| Bertalmio, AJ; Woods, JH | 1 |
| George, R; Pechnick, R; Poland, RE | 1 |
| Dykstra, LA; Gmerek, DE; Winger, G; Woods, JH | 1 |
| Gmerek, DE; Woods, JH | 1 |
| France, CP; Woods, JH | 1 |
| Huidobro-Toro, JP; Parada, S | 1 |
| Amir, S | 1 |
| Michne, WF; Pierson, AK; Ward, SJ | 1 |
| Bermudez-Rattoni, F; Cruz-Morales, S; Reid, LD | 1 |
| Butelman, ER; Gatch, MB; Negus, SS; Woods, JH | 1 |
| Dykstra, LA; Pitts, RC | 1 |
| Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M | 1 |
| Al, Y; Butelman, ER; Negus, SS; Woods, JH | 1 |
| Archer, S; Bidlack, JM; Gatch, MB; Mello, NK; Negus, SS | 1 |
| David Clark, J; Demirci, H; Gharagozlou, P; Lameh, J | 1 |
| Brandt, MR; Gatch, MB; Mello, NK; Negus, SS | 1 |
20 other study(ies) available for quadazocine and morphine
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Anti-arrhythmic activities of opioid agonists and antagonists and their stereoisomers.
Topics: Animals; Anti-Arrhythmia Agents; Azocines; Levorphanol; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Stereoisomerism | 1991 |
Pharmacological characterization of supersensitivity to naltrexone in squirrel monkeys.
Topics: Animals; Azocines; Behavior, Animal; Benzomorphans; Diprenorphine; Drug Administration Schedule; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Saimiri | 1989 |
Opioid receptors and the initiation of migrating myoelectric complexes in dogs.
Topics: Animals; Azocines; Bethanechol; Bethanechol Compounds; Digestive System; Digestive System Physiological Phenomena; Dogs; Duodenum; Electrophysiology; Food; Gastrointestinal Motility; Ileum; Morphine; Motilin; Naloxone; Narcotic Antagonists; Receptors, Opioid; Stereoisomerism; Stomach | 1989 |
Differentiation between mu and kappa receptor-mediated effects in opioid drug discrimination: apparent pA2 analysis.
Topics: Alfentanil; Animals; Azocines; Codeine; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Levorphanol; Macaca mulatta; Male; Morphine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1987 |
Identification of multiple opiate receptors through neuroendocrine responses. II. Antagonism of mu, kappa and sigma agonists by naloxone and WIN 44,441-3.
Topics: Animals; Azocines; Corticosterone; Cyclazocine; Drug Interactions; Ethylketocyclazocine; Growth Hormone; Luteinizing Hormone; Male; Morphine; Naloxone; Narcotic Antagonists; Phenazocine; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and beta-funaltrexamine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Endorphins; Ethylketocyclazocine; Female; Hot Temperature; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Reaction Time; Tail | 1987 |
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1985 |
Antagonistic and rate-suppressing effects of opioid antagonists in the pigeon.
Topics: Animals; Azocines; Benzomorphans; Buprenorphine; Columbidae; Conditioning, Operant; Diprenorphine; Dose-Response Relationship, Drug; Morphine; Naloxone; Naltrexone; Narcotic Antagonists | 1985 |
Kappa-opiates and urination: pharmacological evidence for an endogenous role of the kappa-opiate receptor in fluid and electrolyte balance.
Topics: Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Ethylketocyclazocine; Female; Injections, Intraperitoneal; Morphinans; Morphine; Naloxone; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium; Water-Electrolyte Balance | 1984 |
Morphine exacerbates anaphylactic shock in mice by stimulating central opiate receptors.
Topics: Anaphylaxis; Animals; Azocines; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1983 |
Multiple opioid receptor profile in vitro and activity in vivo of the potent opioid antagonist Win 44,441-3.
Topics: Animals; Azocines; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Naloxone; Narcotic Antagonists; Phenazocine; Receptors, Opioid; Vas Deferens | 1983 |
Addictive agents and intracranial stimulation (ICS): novel antagonists and agonists of morphine and pressing for ICS.
Topics: Animals; Azocines; Brain; Electric Stimulation; Hypothalamic Area, Lateral; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Self Stimulation | 1983 |
Effects of morphine and ketorolac on thermal allodynia induced by prostaglandin E2 and bradykinin in rhesus monkeys.
Topics: Analgesics, Non-Narcotic; Animals; Azocines; Bradykinin; Dinoprostone; Female; Ketorolac; Macaca mulatta; Male; Morphine; Pain; Temperature; Tolmetin | 1995 |
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Saimiri | 1994 |
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail | 1993 |
Prostaglandin E2-induced thermal hyperalgesia and its reversal by morphine in the warm-water tail-withdrawal procedure in rhesus monkeys.
Topics: Animals; Azocines; Data Interpretation, Statistical; Dinoprostone; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain Measurement; Sodium Chloride; Temperature | 1993 |
Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys.
Topics: Analgesics; Animals; Azocines; Behavior, Animal; Benzeneacetamides; Female; Fentanyl; Hot Temperature; Hydromorphone; Macaca mulatta; Male; Morphine; Narcotic Antagonists; Pain; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1996 |
Activity of opioid ligands in cells expressing cloned mu opioid receptors.
Topics: Azocines; beta-Endorphin; Binding, Competitive; Butorphanol; Cell Line; Colforsin; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fentanyl; Humans; Hydromorphone; Ligands; Morphine; Naltrexone; Phenazocine; Radioligand Assay; Receptors, Opioid, mu; Tritium | 2003 |
Effects of heroin and its metabolites on schedule-controlled responding and thermal nociception in rhesus monkeys: sensitivity to antagonism by quadazocine, naltrindole and beta-funaltrexamine.
Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Food; Heroin; Hot Temperature; Macaca mulatta; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Pain Measurement | 2003 |