Compounds > quadazocine
Page last updated: 2024-09-03

quadazocine and beta-funaltrexamine

quadazocine has been researched along with beta-funaltrexamine in 7 studies

Compound Research Comparison

Studies
(quadazocine)		Trials
(quadazocine)		Recent Studies (post-2010)
(quadazocine)		Studies
(beta-funaltrexamine)		Trials
(beta-funaltrexamine)		Recent Studies (post-2010) (beta-funaltrexamine)
8100542154

Protein Interaction Comparison

ProteinTaxonomyquadazocine (IC50)beta-funaltrexamine (IC50)
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.082
Prostaglandin G/H synthase 1Homo sapiens (human)0.082
Delta-type opioid receptorMus musculus (house mouse)0.082
Kappa-type opioid receptorMus musculus (house mouse)0.082
Mu-type opioid receptorMus musculus (house mouse)0.082

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A1
Dykstra, LA; Gmerek, DE; Winger, G; Woods, JH1
Gmerek, DE; Woods, JH1
France, CP; Woods, JH1
Dykstra, LA; Pitts, RC1
Brandt, MR; Gatch, MB; Mello, NK; Negus, SS1
Clithero, AD; Leitermann, RJ; MacDougall, RS; Terashvili, M; Tseng, LF; Wu, HE1

Other Studies

7 other study(ies) available for quadazocine and beta-funaltrexamine

ArticleYear
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
    NIDA research monograph, 1998, Volume: 178

    Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders

1998
Kappa opioids in rhesus monkeys. II. Analysis of the antagonistic actions of quadazocine and beta-funaltrexamine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Diuresis; Endorphins; Ethylketocyclazocine; Female; Hot Temperature; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Reaction Time; Tail

1987
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1985
Antagonistic and rate-suppressing effects of opioid antagonists in the pigeon.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Animals; Azocines; Benzomorphans; Buprenorphine; Columbidae; Conditioning, Operant; Diprenorphine; Dose-Response Relationship, Drug; Morphine; Naloxone; Naltrexone; Narcotic Antagonists

1985
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Saimiri

1994
Effects of heroin and its metabolites on schedule-controlled responding and thermal nociception in rhesus monkeys: sensitivity to antagonism by quadazocine, naltrindole and beta-funaltrexamine.
    Drug and alcohol dependence, 2003, May-01, Volume: 70, Issue:1

    Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Food; Heroin; Hot Temperature; Macaca mulatta; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Pain Measurement

2003
Opposite conditioned place preference responses to endomorphin-1 and endomorphin-2 in the mouse.
    Neuroscience letters, 2004, Jul-29, Volume: 365, Issue:3

    Topics: Animals; Azocines; Conditioning, Operant; Injections, Intraventricular; Ligands; Male; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2004