pyruvic acid and uridine

pyruvic acid has been researched along with uridine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's10 (43.48)18.2507
2000's9 (39.13)29.6817
2010's1 (4.35)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Hobbs, GA; Keilbaugh, SA; Simpson, MV1
Friedman, S; Gao, JP; Lanks, KW1
Hill, JS; Kahl, SB; Munday, AD; Nagley, P; Sriratana, A1
Freeman Emmerson, C; Morten, KJ; Poulton, J1
Cartwright, P; Garth, GP; Hoogenraad, NJ; Høj, PB; Martinus, RD; Naylor, DJ; Webster, TL1
Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Ohata, H; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T1
Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T1
Cavadini, P; Cortopassi, G; Gellera, C; Lonnerdal, B; Taroni, F; Wong, A; Yang, J1
Higashino, K; Moriwaki, Y; Nakano, T; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T1
Cass, CE; Cheeseman, CI; Muzyka, WR; Yao, SY; Young, JD1
Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T1
Hada, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
Fukuyama, R; Fushiki, S; Mukainaka, T; Nakase, T; Nakayama, A; Saiwaki, T; Sakaguchi, H; Sakurai, H; Toba, H; Wada, M1
Fukuchi, M; Hada, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
STROMINGER, JL1
Fukuchi, M; Hada, T; Inokuchi, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
Bal-Price, A; Brown, GC; Gartlon, J1
Almeida, C; Barros, A; Duarte, IF; Gil, AM; Rodrigues, J; Spraul, M1
Banerjee, B; Das, BB; Ganguly, A; Gupta, SS; Majumder, HK; Sen, N1
Barrientos, A; Bayona-Bafaluy, MP; Enriquez, JA; Fernández-Silva, P; Perales-Clemente, E; Pérez-Martos, A1
Baghdoyan, HA; Bellesi, M; Bourdon, AK; Campagna, SR; Cirelli, C; Lydic, R; Marshall, W; Serra, PA; Spano, GM; Tononi, G1
Battaglia, M; Battaglia, S; De Santis, S; Frassanito, MA; Moschetta, A; Picerno, A; Rutigliano, M; Sallustio, F; Schaefer, I; Seibel, P; Vacca, A; Villani, G1
Adant, I; Bird, M; Cassiman, D; de Witte, P; Decru, B; Ghesquière, B; Rymen, D; Vermeersch, P; Wallays, M; Windmolders, P; Witters, P1

Trials

3 trial(s) available for pyruvic acid and uridine

ArticleYear
Effect of glucose on the plasma concentration and urinary excretion of uridine and purine bases.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:3

    Topics: Adult; Blood Glucose; Glucagon; Glucose; Humans; Insulin; Lactic Acid; Male; Middle Aged; Phosphates; Purines; Pyruvic Acid; Uridine

1999
Effect of branched-chain amino acids on the plasma concentration of uridine does not occur via the action of glucagon or insulin.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:1

    Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Blood Glucose; Creatinine; Cyclic AMP; Glucagon; Humans; Insulin; Lactic Acid; Phosphates; Purines; Pyruvic Acid; Uridine

2000
Effect of beer on the plasma concentrations of uridine and purine bases.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:10

    Topics: Adult; Beer; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Ethanol; Freeze Drying; Humans; Hypoxanthine; Lactic Acid; Male; Middle Aged; Purines; Pyrimidines; Pyruvic Acid; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthines

2002

Other Studies

20 other study(ies) available for pyruvic acid and uridine

ArticleYear
Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate.
    Molecular pharmacology, 1993, Volume: 44, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Cell Survival; DNA Replication; DNA, Mitochondrial; HIV-1; Models, Biological; Neurons; PC12 Cells; Peripheral Nervous System Diseases; Pyruvates; Pyruvic Acid; Uridine; Zalcitabine

1993
The role of reduced nicotinamide adenine dinucleotide phosphate in glucose- and temperature-dependent doxorubicin cytotoxicity.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:3

    Topics: Animals; Cell Survival; Culture Media; DNA Damage; Doxorubicin; Drug Resistance; Glucose; Glutamine; L Cells; Methylene Blue; Mice; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Temperature; Uridine

1993
Mitochondria are the functional intracellular target for a photosensitizing boronated porphyrin.
    Biochimica et biophysica acta, 1996, Mar-27, Volume: 1311, Issue:1

    Topics: Boron Compounds; Deuteroporphyrins; DNA, Mitochondrial; Electron Transport; Humans; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Photosensitizing Agents; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured; Uridine

1996
Functional mtDNA replication defect in a fibroblast line from a patient with mtDNA depletion.
    Journal of inherited metabolic disease, 1996, Volume: 19, Issue:2

    Topics: Cell Division; Cells, Cultured; Culture Media; DNA Replication; DNA, Mitochondrial; Fibroblasts; Humans; Pyruvates; Pyruvic Acid; Uridine

1996
Selective induction of mitochondrial chaperones in response to loss of the mitochondrial genome.
    European journal of biochemistry, 1996, Aug-15, Volume: 240, Issue:1

    Topics: Animals; Blotting, Western; Cell Nucleus; Clone Cells; Cytosol; DNA, Mitochondrial; DNA, Neoplasm; Ethidium; Fluorescent Antibody Technique, Indirect; Heat-Shock Proteins; Hot Temperature; HSP70 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Liver Neoplasms, Experimental; Mitochondria; Molecular Chaperones; Polymerase Chain Reaction; Pyruvic Acid; Rats; Transcription, Genetic; Uridine

1996
Effect of glucagon on the plasma concentration of uridine.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:6

    Topics: Adult; Blood Glucose; Cyclic AMP; Glucagon; Humans; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvic Acid; Uridine

1998
Xylitol-induced increase in the plasma concentration and urinary excretion of uridine and purine bases.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:6

    Topics: Adult; Humans; Hypoxanthine; Injections, Intravenous; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvic Acid; Uric Acid; Uridine; Xanthine; Xylitol

1998
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis.
    Human molecular genetics, 1999, Volume: 8, Issue:3

    Topics: Apoptosis; Base Sequence; Calcium; Case-Control Studies; Caspase 3; Caspases; Cell Line; Chelating Agents; Deferoxamine; DNA Primers; Egtazic Acid; Fibroblasts; Frataxin; Friedreich Ataxia; Humans; Hydrogen Peroxide; Iron; Iron-Binding Proteins; Mutation; Oxidative Stress; Phosphotransferases (Alcohol Group Acceptor); Pyruvic Acid; RNA, Messenger; Uridine

1999
Evidence that the transport-related proteins BAT and 4F2hc are not specific for amino acids: induction of Na+-dependent uridine and pyruvate transport activity by recombinant BAT and 4F2hc expressed in Xenopus oocytes.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1998, Volume: 76, Issue:5

    Topics: Animals; Antigens, CD; Bacterial Proteins; Carrier Proteins; Choline; Escherichia coli Proteins; Fusion Regulatory Protein-1; Leucine; Mice; Oocytes; Pyruvic Acid; Rats; Uridine; Xenopus

1998
Effect of octreotide acetate on the plasma concentration and urinary excretion of uridine and purine bases.
    Endocrine journal, 2002, Volume: 49, Issue:2

    Topics: Adult; Blood Glucose; Chlorides; Creatinine; Cyclic AMP; Glucagon; Hormones; Humans; Insulin; Lactic Acid; Middle Aged; Octreotide; Purines; Pyruvic Acid; Sodium; Uridine

2002
A newly established neuronal rho-0 cell line highly susceptible to oxidative stress accumulates iron and other metals. Relevance to the origin of metal ion deposits in brains with neurodegenerative disorders.
    The Journal of biological chemistry, 2002, Nov-01, Volume: 277, Issue:44

    Topics: Brain; Cell Respiration; Copper; Glycolysis; Humans; Hydrogen Peroxide; Iron; Membrane Potentials; Microscopy, Electron; Mitochondria; Neuroblastoma; Neurodegenerative Diseases; Oxidative Stress; Pyruvic Acid; Tumor Cells, Cultured; Uridine

2002
Enzymic transfer of pyruvate to uridine diphosphoacetylglucosamine.
    Biochimica et biophysica acta, 1958, Volume: 30, Issue:3

    Topics: Bacteria; Biochemical Phenomena; Nucleosides; Nucleotides; Pyruvates; Pyruvic Acid; Uridine

1958
Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:4

    Topics: Adult; Beer; Central Nervous System Depressants; Creatinine; Edible Grain; Ethanol; Humans; Lactic Acid; Male; Middle Aged; Purines; Pyrimidines; Pyruvic Acid; Uric Acid; Uridine

2004
Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:3

    Topics: Acetylcysteine; Animals; Cell Proliferation; Cell Respiration; Cyclic GMP; Glycolysis; Guanylate Cyclase; Macrophage Activation; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; PC12 Cells; Poly(ADP-ribose) Polymerase Inhibitors; Pyruvic Acid; Rats; Ribonucleotide Reductases; Triazenes; Uridine

2006
Composition of beer by 1H NMR spectroscopy: effects of brewing site and date of production.
    Journal of agricultural and food chemistry, 2006, Feb-08, Volume: 54, Issue:3

    Topics: Adenosine; Beer; Dextrins; Environment; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results; Time Factors; Tyrosine; Uridine

2006
Leishmania donovani: dyskinetoplastid cells survive and proliferate in the presence of pyruvate and uridine but do not undergo apoptosis after treatment with camptothecin.
    Experimental parasitology, 2007, Volume: 115, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Camptothecin; DNA, Mitochondrial; Enzyme Inhibitors; Glutathione; Lactates; Leishmania donovani; Luteolin; Membrane Potentials; Mitochondria; Pyruvic Acid; Reactive Oxygen Species; Topoisomerase I Inhibitors; Uridine

2007
Restoration of electron transport without proton pumping in mammalian mitochondria.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-02, Volume: 105, Issue:48

    Topics: Animals; Cell Line; Dichloroacetic Acid; DNA, Mitochondrial; Electron Transport; Electron Transport Complex I; Fungal Proteins; Humans; Lactic Acid; Mice; Mitochondria; Mitochondrial Proteins; NADH Dehydrogenase; Oxidation-Reduction; Oxidoreductases; Oxygen; Plant Proteins; Proton Pumps; Protons; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Transformation, Genetic; Ubiquinone; Uridine

2008
Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep.
    Scientific reports, 2018, 07-25, Volume: 8, Issue:1

    Topics: Animals; Glutamic Acid; Homovanillic Acid; Humans; Lactic Acid; Metabolomics; Mice; Motor Cortex; Prefrontal Cortex; Pyruvic Acid; Sleep; Sleep Deprivation; Tryptophan; Uridine; Wakefulness

2018
Uridine and pyruvate protect T cells' proliferative capacity from mitochondrial toxic antibiotics: a clinical pilot study.
    Scientific reports, 2021, 06-18, Volume: 11, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Bacteriuria; Biomarkers; Female; Humans; Lymphocyte Activation; Male; Mitochondria; Pilot Projects; Protective Agents; Pyruvic Acid; T-Lymphocytes; Uridine

2021
Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction.
    Molecular metabolism, 2022, Volume: 63

    Topics: Animals; Metabolome; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Pyruvic Acid; Rotenone; Uridine; Zebrafish

2022