pyruvic acid and ubiquinone

pyruvic acid has been researched along with ubiquinone in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's10 (38.46)18.2507
2000's7 (26.92)29.6817
2010's4 (15.38)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Abe, K; Fujimura, H; Hirono, N; Kameyama, M; Mezaki, T; Nishikawa, Y; Nishitani, N; Yorifuji, S1
Ishikura, Y; Nagano, T; Nagata, M; Odagiri, S; Yoshimatu, H1
Fujita, T; Imada, I; Matsumoto, M; Okamoto, K; Sugiyama, Y1
Hashimoto, S; Kitaguchi, M; Nishikawa, Y; Takahashi, M; Tarui, S; Tatsumi, C; Yorifuji, S1
Nakatomi, Y1
Berry, JA; Ribas-Carbo, M; Siedow, JN; Wiskich, JT1
Linnane, AW; Martinus, RD; Nagley, P1
Krab, K; Leach, GR; Moore, AL; Whitehouse, DG1
Ammi-Saïd, M; Astier, A; Chariot, P; De Pinieux, G; Gherardi, R; Jacotot, B; Lejonc, JL; Louarn, F1
Chen, RS; Chu, NS; Huang, CC1
Bach, TJ; Disch, A; Hemmerlin, A; Rohmer, M1
Arp, S; Chan, A; Gold, R; Pflughaupt, KW; Reichmann, H; Toyka, KV1
Hoefnagel, MH; Wiskich, JT1
Oliveira, C; Pereira, C; Santos, MS1
Babij, J; Hollomon, D; Joseph-Horne, T; Sessions, RB; Wood, PM1
Choi, C; Kim, DI; Kim, HS; Sunwoo, IN1
Henze, K; Hoffmeister, M; Martin, W; Rotte, C; Tielens, AG; van der Klei, A; van Grinsven, KW; van Hellemond, JJ1
Kunz, WS; Wallesch, CW; Wiedemann, FR; Winkler-Stuck, K1
Hoppel, CL; Kayser, EB; Morgan, PG; Sedensky, MM1
Barrientos, A; Bayona-Bafaluy, MP; Enriquez, JA; Fernández-Silva, P; Perales-Clemente, E; Pérez-Martos, A1
Hargreaves, I; Kyprianou, N; Lee, P; Murphy, E1
Dong, DK; Fu, LJ; Jiang, YP; Li, X; Liang, WS; Liao, YW; Shi, K; Xia, XJ; Yu, JQ; Zhang, S; Zhou, YH1
Chen, Q; Hoppel, CL; Kern, TS; Kerner, J; Rosca, MG; Vazquez, EJ1
Audi, SH; Bongard, RD; Hoffmann, RG; Lindemer, BJ; Merker, MP; Townsley, MI; Yan, K; Zhang, X1
Abdallah, D; El-Ganainy, SO; El-Khatib, AS; El-Mallah, A; Khattab, MM; Mohy El-Din, MM1
Blackmore, D; Li, L; Maksymowych, W; Siddiqi, ZA; Wang, N; Yacyshyn, E1

Trials

1 trial(s) available for pyruvic acid and ubiquinone

ArticleYear
Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study.
    European neurology, 1997, Volume: 37, Issue:4

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Coenzymes; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Encephalomyopathies; Neurologic Examination; Physical Endurance; Pyruvic Acid; Ubiquinone

1997

Other Studies

25 other study(ies) available for pyruvic acid and ubiquinone

ArticleYear
Marked reduction in CSF lactate and pyruvate levels after CoQ therapy in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS).
    Acta neurologica Scandinavica, 1991, Volume: 83, Issue:6

    Topics: Acidosis, Lactic; Adult; Agnosia; Cerebrovascular Disorders; Delirium; Dose-Response Relationship, Drug; Hemianopsia; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Mitochondria, Muscle; Neurologic Examination; Neuromuscular Diseases; Pyruvates; Pyruvic Acid; Syndrome; Ubiquinone

1991
[Effects of coenzyme Q10 on ischemic myocardium during coronary artery occlusion--evaluation of the time needed to change irreversible myocardium].
    Journal of UOEH, 1986, Mar-01, Volume: 8, Issue:1

    Topics: Alanine Transaminase; Animals; Coenzymes; Dogs; Hemodynamics; Mitochondria, Heart; Myocardial Infarction; Myocardium; Pyruvates; Pyruvic Acid; Staining and Labeling; Time Factors; Ubiquinone

1986
Effects of idebenone (CV-2619) and its metabolites on respiratory activity and lipid peroxidation in brain mitochondria from rats and dogs.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:12

    Topics: Animals; Benzoquinones; Brain Chemistry; Dogs; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lipid Peroxides; Malates; Male; Mitochondria; NADP; Oxygen Consumption; Pantothenic Acid; Pyruvates; Pyruvic Acid; Quinones; Rats; Rats, Inbred Strains; Respiration; Species Specificity; Succinates; Ubiquinone

1985
Mitochondrial encephalomyopathy with sleep apnea.
    European neurology, 1988, Volume: 28, Issue:2

    Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Diseases; Pyruvates; Pyruvic Acid; Radiography; Sleep Apnea Syndromes; Ubiquinone

1988
[Effect of recirculation on experimental cerebral ischemia. 3. Therapy].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1982, Volume: 73, Issue:9

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Dexamethasone; Glycerol; Hypertension; Lactates; Lactic Acid; Ligation; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Ubiquinone

1982
Ubiquinone redox behavior in plant mitochondria during electron transport.
    Archives of biochemistry and biophysics, 1995, Feb-20, Volume: 317, Issue:1

    Topics: Chromatography, High Pressure Liquid; Electron Transport; Glycine max; Mitochondria; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Ubiquinone

1995
Growth of rho 0 human Namalwa cells lacking oxidative phosphorylation can be sustained by redox compounds potassium ferricyanide or coenzyme Q10 putatively acting through the plasma membrane oxidase.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:6

    Topics: Cell Division; Cell Line; Cell Membrane; Coenzymes; Culture Media; DNA, Mitochondrial; Ferricyanides; Humans; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid; Ubiquinone

1993
Kinetic analysis of the mitochondrial quinol-oxidizing enzymes during development of thermogenesis in Arum maculatum L.
    The Biochemical journal, 1996, Jul-01, Volume: 317 ( Pt 1)

    Topics: Cold Temperature; Electron Transport; Enzyme Activation; Hot Temperature; Kinetics; Mitochondria; Mitochondrial Proteins; Oxidoreductases; Oxygen Consumption; Plant Development; Plant Proteins; Plants; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase; Succinates; Succinic Acid; Ubiquinone

1996
Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:3

    Topics: Adult; Aged; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lactic Acid; Male; Middle Aged; Mitochondria; Pyruvic Acid; Ubiquinone

1996
Mevalonate-derived isopentenyl diphosphate is the biosynthetic precursor of ubiquinone prenyl side chain in tobacco BY-2 cells.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Acetyl Coenzyme A; Carbon Isotopes; Cell Line; Coenzymes; Glucose; Glyceraldehyde 3-Phosphate; Hemiterpenes; Mevalonic Acid; Mitochondria; Nicotiana; Organophosphorus Compounds; Plants, Toxic; Plastoquinone; Polyisoprenyl Phosphates; Pyruvic Acid; Sterols; Ubiquinone

1998
[Standardized bicycle ergometry test in mitochondrial myopathies. Indications, interferences and clinical parameters].
    Der Nervenarzt, 1998, Volume: 69, Issue:6

    Topics: Adult; Energy Metabolism; Exercise Test; Female; Humans; Isometric Contraction; Lactic Acid; Male; Middle Aged; Mitochondrial Myopathies; Pyruvic Acid; Reference Values; Sensitivity and Specificity; Ubiquinone

1998
Activation of the plant alternative oxidase by high reduction levels of the Q-pool and pyruvate.
    Archives of biochemistry and biophysics, 1998, Jul-15, Volume: 355, Issue:2

    Topics: Blotting, Western; Dithiothreitol; Enzyme Activation; Glycine max; Magnoliopsida; Mitochondrial Proteins; NAD; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Pyruvic Acid; Succinic Acid; Ubiquinone

1998
Involvement of oxidative stress on the impairment of energy metabolism induced by A beta peptides on PC12 cells: protection by antioxidants.
    Neurobiology of disease, 1999, Volume: 6, Issue:3

    Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Animals; Antioxidants; Benzoquinones; Deoxyglucose; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Glutathione; Glycolysis; Mitochondria; Multienzyme Complexes; NAD(P)H Dehydrogenase (Quinone); Neurons; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; PC12 Cells; Peptide Fragments; Pyruvic Acid; Rats; Succinate Dehydrogenase; Tritium; Ubiquinone; Vitamin E

1999
New sequence data enable modelling of the fungal alternative oxidase and explain an absence of regulation by pyruvate.
    FEBS letters, 2000, Sep-15, Volume: 481, Issue:2

    Topics: Amino Acid Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Cysteine; Dimerization; Fungi; Holoenzymes; Mitochondria; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; NAD; Oxidation-Reduction; Oxidoreductases; Oxygen; Plant Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvic Acid; Sequence Alignment; Ubiquinone

2000
Transient improvement of pyruvate metabolism after coenzyme Q therapy in Kearns-Sayre syndrome: MRS study.
    Yonsei medical journal, 2000, Volume: 41, Issue:5

    Topics: Adolescent; Brain; Female; Humans; Kearns-Sayre Syndrome; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Treatment Outcome; Ubiquinone

2000
Euglena gracilis rhodoquinone:ubiquinone ratio and mitochondrial proteome differ under aerobic and anaerobic conditions.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Animals; Biochemistry; Cloning, Molecular; Databases as Topic; DNA, Complementary; Electron Transport; Electrophoresis, Gel, Two-Dimensional; Euglena gracilis; Expressed Sequence Tags; Gene Expression Regulation, Bacterial; Hydrogen; Mitochondria; Models, Chemical; Molecular Sequence Data; Oxygen; Peptides; Phylogeny; Protein Structure, Tertiary; Proteome; Pyruvic Acid; Trypsin; Ubiquinone

2004
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients.
    Journal of the neurological sciences, 2004, May-15, Volume: 220, Issue:1-2

    Topics: Adenosine Diphosphate; Adult; Aged; Amobarbital; Antioxidants; Cells, Cultured; Coenzymes; Drug Interactions; Female; Fibroblasts; Glutamic Acid; Humans; Male; Middle Aged; Mitochondria; NAD; Oxygen; Parkinson Disease; Pyruvic Acid; Skin; Ubiquinone

2004
Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1.
    The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52

    Topics: Animals; Ascorbic Acid; Caenorhabditis elegans; Electron Transport Complex I; Electron Transport Complex II; Glutamic Acid; Hydroquinones; Malates; Mitochondria; Mutation; Oxidative Phosphorylation; Pyruvic Acid; Quinones; Substrate Specificity; Tetramethylphenylenediamine; Time Factors; Ubiquinone

2004
Restoration of electron transport without proton pumping in mammalian mitochondria.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-02, Volume: 105, Issue:48

    Topics: Animals; Cell Line; Dichloroacetic Acid; DNA, Mitochondrial; Electron Transport; Electron Transport Complex I; Fungal Proteins; Humans; Lactic Acid; Mice; Mitochondria; Mitochondrial Proteins; NADH Dehydrogenase; Oxidation-Reduction; Oxidoreductases; Oxygen; Plant Proteins; Proton Pumps; Protons; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Transformation, Genetic; Ubiquinone; Uridine

2008
Assessment of mitochondrial respiratory chain function in hyperphenylalaninaemia.
    Journal of inherited metabolic disease, 2009, Volume: 32, Issue:2

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Cell Line, Tumor; Cells, Cultured; Culture Media; Electron Transport; Female; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Diseases; Phenylalanine; Phenylketonurias; Pyruvic Acid; Tremor; Tyrosine; Ubiquinone; Young Adult

2009
The reduction of reactive oxygen species formation by mitochondrial alternative respiration in tomato basal defense against TMV infection.
    Planta, 2012, Volume: 235, Issue:2

    Topics: Antioxidants; Cell Respiration; Dehydroascorbic Acid; Disease Resistance; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genes, Plant; Hydrogen Peroxide; Mitochondria; Mitochondrial Proteins; Oxidation-Reduction; Oxidoreductases; Plant Leaves; Plant Proteins; Potassium Cyanide; Pyruvic Acid; Reactive Oxygen Species; Salicylamides; Solanum lycopersicum; Tobacco Mosaic Virus; Transcription, Genetic; Ubiquinone

2012
Oxidation of fatty acids is the source of increased mitochondrial reactive oxygen species production in kidney cortical tubules in early diabetes.
    Diabetes, 2012, Volume: 61, Issue:8

    Topics: Animals; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Fatty Acids; Kidney Tubules, Proximal; Male; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Ubiquinone

2012
Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Blood-Air Barrier; Capillary Permeability; Electron Transport Complex I; Electron Transport Complex III; Endothelium, Vascular; Energy Metabolism; Glycolysis; Lactic Acid; Lung; Lung Injury; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyridines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion; Rotenone; Ubiquinone; Uncoupling Agents

2013
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model.
    Toxicology, 2016, 06-01, Volume: 359-360

    Topics: Adenosine Triphosphate; Animals; Atorvastatin; Creatine Kinase; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lactic Acid; Male; Microscopy, Electron, Transmission; Mitochondria, Muscle; Motor Activity; Muscle, Skeletal; Muscular Diseases; Myoglobin; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ubiquinone

2016
Metabolomic profile overlap in prototypical autoimmune humoral disease: a comparison of myasthenia gravis and rheumatoid arthritis.
    Metabolomics : Official journal of the Metabolomic Society, 2020, 01-04, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Humans; Male; Metabolic Networks and Pathways; Metabolome; Middle Aged; Myasthenia Gravis; Phenylalanine; Pyruvic Acid; Tyrosine; Ubiquinone

2020