Compounds > pyruvic acid

pyruvic acid and sirolimus

pyruvic acid has been researched along with sirolimus in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Kahn, BB; Li, H; Liu, L; Najjar, SM; Shah, W; Xie, Z1
Astle, CM; Baur, JA; Harrison, DE; Lamming, DW; Sabatini, DM; Ye, L1
Partap, U; Patchen, BK; Schindler, CE; Swoap, SJ1
Aldeborgh, HN; Alvarez, JA; DiGialleonardo, V; Eskandari, R; Granlund, KL; Jeong, S; Keshari, KR; Miloushev, V; Poot, AJ; Tee, SS; Truong, S1
Ando, A; Araki, H; Hara, T; Honda, K; Kitazawa, S; Morimoto, M; Nishizawa, S; Nutahara, K; Okegawa, T; Satomi, Y; Tamura, T1
Aras, O; Chen, YB; Cheng, EH; Dong, Y; Eskandari, R; Granlund, KL; Hsieh, JJ; Jeong, S; Keshari, KR; Miloushev, VZ; Ray, C; Santos-Cunha, LD; Tee, SS1
Balasubramanian, R; Cardozo, BH; Casson, RJ; Chidlow, G; Daskalaki, E; Deering, KE; Foxworth, NE; Guymer, C; Harder, JM; John, SWM; Montgomery, C; Ouellette, TB; Wheelock, CE; Williams, PA; Wood, JPM; Zhang, C1
Altea-Manzano, P; Broekaert, D; Doglioni, G; Fendt, SM; Funk, CM; Geldhof, V; Grünewald, TGP; Hunter, KW; Lunt, SY; Planque, M; Pranzini, E; Rinaldi, G; Ross, C; Rossi, M; Teoh, ST; Van Elsen, J1

Other Studies

8 other study(ies) available for pyruvic acid and sirolimus

ArticleYear
Metabolic regulation of Na(+)/P(i)-cotransporter-1 gene expression in H4IIE cells.
    American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:4

    Topics: Adenoviridae; Androstadienes; Animals; Antibiotics, Antineoplastic; Blotting, Northern; Carrier Proteins; Cell Line; Cell Nucleus; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Hypoglycemic Agents; Insulin; Liver Neoplasms, Experimental; Mitogen-Activated Protein Kinase 1; Pyruvic Acid; Rats; RNA, Messenger; Signal Transduction; Sirolimus; Sodium-Phosphate Cotransporter Proteins; Symporters; Transcription, Genetic; Wortmannin

2000
Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.
    Aging cell, 2013, Volume: 12, Issue:4

    Topics: Age Factors; Animals; Blood Glucose; Diet; Female; Genetic Heterogeneity; Genotype; Glucose; Glucose Intolerance; Glycated Hemoglobin; Insulin Resistance; Longevity; Male; Mice; Mice, Inbred C57BL; Pyruvic Acid; Sirolimus; Species Specificity

2013
Chronic rapamycin treatment causes diabetes in male mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus; Estradiol; Estrogen Replacement Therapy; Female; Glucose Intolerance; Glycosuria; Male; Mice; Orchiectomy; Ovariectomy; Pancreas; Protein Kinase Inhibitors; Pyruvic Acid; Sex Factors; Sirolimus; Testosterone; Time Factors; TOR Serine-Threonine Kinases

2014
Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field.
    Scientific reports, 2016, 09-06, Volume: 6

    Topics: Animals; Antibiotics, Antineoplastic; Humans; Lactic Acid; Magnetic Fields; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms; Pyruvic Acid; Sarcoma; Sirolimus; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors.
    EBioMedicine, 2017, Volume: 19

    Topics: Acrylates; Animals; Antineoplastic Agents; Cells, Cultured; Female; Glycolysis; Humans; Kidney Neoplasms; Metabolomics; Mice; Pyruvic Acid; Sirolimus; Xenograft Model Antitumor Assays

2017
Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models.
    Cancer research, 2019, 01-01, Volume: 79, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Renal Cell; Humans; Image Processing, Computer-Assisted; Kidney Neoplasms; Magnetic Resonance Imaging; Mice; Pyruvic Acid; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-29, Volume: 117, Issue:52

    Topics: Animals; Disease Models, Animal; Glaucoma; Glucose; Intraocular Pressure; Mice, Inbred C57BL; Mice, Inbred DBA; Nerve Degeneration; Neuroprotection; Neuroprotective Agents; Pyruvic Acid; Rats, Sprague-Dawley; Retina; Sirolimus; TOR Serine-Threonine Kinases

2020
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
    Molecular cell, 2021, 01-21, Volume: 81, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ketoglutaric Acids; Lung Neoplasms; Mammary Neoplasms, Experimental; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred BALB C; Mice, Nude; Monocarboxylic Acid Transporters; Phosphoglycerate Dehydrogenase; Pyruvic Acid; RNA, Small Interfering; Serine; Signal Transduction; Sirolimus

2021