pyruvic acid and serine

pyruvic acid has been researched along with serine in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199016 (23.19)18.7374
1990's7 (10.14)18.2507
2000's18 (26.09)29.6817
2010's20 (28.99)24.3611
2020's8 (11.59)2.80

Authors

AuthorsStudies
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Diamond, LS; Gottlieb, M; Takeuchi, T; Weinbach, EC1
Fischer, Y; Kammermeier, H; Rose, H1
Niedzielska, A; Paszkowski, A1
Kwon-Chung, KJ; Min, KH1
Garbow, JR; Jacob, GS; Kishore, GM; Schaefer, J1
Clary, GL; Guynn, RW1
Selak, I; Skaper, SD; Varon, S1
Colebrook, LD; Miller, B; Newman, EB; Walker, C1
Recsei, PA; Snell, EE1
Gierlach, P; Hörl, WH; Kluthe, R; Schollmeyer, P1
Miller, RD; Morse, SA; Tesh, MJ1
Kumaoka, H; Yamada, K1
Manthorpe, M; Selak, I; Skaper, SD; Varon, S1
Crompton, DW; Ward, PF1
Feldhaus, RW; Likos, JJ; Metzler, DE; Ueno, H1
Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN1
Shirley, B1
Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U1
Pegg, AE; Stanley, BA; Tekwani, BL; Xiong, H1
Chait, BT; Erickson, SD; Haller, I; Manning, JM; Martinez del Pozo, A; Petsko, G; Ringe, D; Soda, K; van Ophem, PW; Yoshimura, T1
De Miranda, J; Engelender, S; Panizzutti, R; Ribeiro, CS; Wolosker, H1
Dunn, MF; Ferrari, D; Miles, EW; Yang, LH1
Gonzàlez-Meler, MA; Siedow, JN; Sweet, CR; Umbach, AL1
Herrington, MB; MacRae, TJ; Panagopoulos, D; Wong, SH1
De Miranda, J; Foltyn, VN; Panizzutti, R; Wolosker, H1
Barinka, C; Jirásková, J; Konvalinka, J; Majer, P; Rojas, C; Slusher, BS; Strísovský, K1
Fujino, MA; Nagata, K; Nagata, Y; Nakajima, K; Sato, T; Tamura, T1
BRICTEUX, S; DEWANDRE, A; FLORKIN, M; FUKUDA, T1
FROMAGEOT, P; POUZAT, J; RODERICK, UR1
NYC, JF; ZABIN, I1
Jacobsen, M; Lock, EA; Williams, RE1
Aitken, SM; Kirsch, JF1
Chaudhary, LC; McKain, N; Miyagawa, E; Walker, ND; Wallace, RJ1
Dunlop, DS; Neidle, A1
Locas, CP; O'Brien, J; Wnorowski, A; Yaylayan, VA1
Hemmi, H; Ito, T; Naka, T; Takahashi, K; Yoshimura, T1
Alam, T; Hoshino, E; Hossain, MZ; Ikeda, T; Kuvatanasuchati, J; Uematsu, H1
Christopherson, MR; Downs, DM; Schmitz, GE1
Gauthier, MS; Gerhart-Hines, Z; Ido, Y; Kelly, M; Nelson, LE; Puigserver, P; Ruderman, NB; Saha, AK; Suchankova, G1
Dierkers, AT; Dunn, MF; Niks, D; Schlichting, I1
Burnet, PW; Cockayne, R; Harrison, PJ; Sikka, P; Walker, R; Wood, MJ1
de Koning, TJ; Dorland, B; Keularts, IM; Leroy, PL; Rubio-Gozalbo, EM; Spaapen, LJ; Verhoeven-Duif, NM; Weber, B1
Horiike, K; Ishida, T; Murakami, M; Nagata, Y; Suzuki, C; Tanaka, H; Yokobori, H1
Kato, F; Shigetomi, E1
Chai, X; Lai, S; Liang, Y; Liu, S; Shang, X; Wen, T; Zhang, Y1
Chai, LC; Elemfareji, OI; Kong, BH; Thong, KL1
Grant, GA1
Chaneton, B; Chokkathukalam, A; Coyle, JE; Frezza, C; Gottlieb, E; Hillmann, P; Holding, FP; Jankevics, A; Maddocks, ODK; Martin, ACL; O'Reilly, M; Vousden, KH; Zheng, L1
Badertscher, R; Bavan, T; Berthoud, H; Guggenbühl, B; Irmler, S; Oberli, A; Roetschi, A1
Gatermann, SG; Hultgren, S; Kline, K; Korte-Berwanger, M; Nielsen, HV; Sakinc, T1
Chen, L; Cui, Z; Fu, W; Liao, X; Luo, Z; Zhou, J1
Alves, PM; Barreiro, LC; Carinhas, N; Carrondo, MJ; Duarte, TM; Teixeira, AP1
Al-Haideri, H; Kelly, DJ; White, MA1
Artyomov, MN; Avizonis, D; Blagih, J; Bridon, G; Choinière, L; Coelho, PP; Elder, DJ; Flynn, BR; Gingras, MC; Griss, T; Jones, RG; Loginicheva, E; Ntimbane, T; Pause, A; Raissi, TC; Samborska, B; Sergushichev, A; Tavaré, JM; Thomas, EC; Vincent, EE1
Becker-Kettern, J; Conrotte, JF; Guignard, C; Jung, PP; Kay, DP; Linster, CL; Paczia, N1
Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K1
Bouzon, M; Delmas, V; Loreau, O; Marlière, P; Perchat, N; Perret, A; Taran, F; Weissenbach, J1
Huynh, S; Parker, CT; van de Lest, CHA; van der Stel, AX; van Putten, JPM; Wösten, MMSM1
Atsumi, S; Hirano, S; Kondo, A; Matson, MM; Tashiro, Y1
Cheng, A; Ding, C; Duan, X; Gao, P; Guo, J; Jiang, Y; Pan, X; Pan, YY; Sang, Z; Shi, J; Wang, B; Wang, H; Wu, G; Wu, M; Wu, Q; Xu, T; Yang, D; Yang, Z; Zhang, H; Zhang, P; Zhang, Z; Zhou, CZ1
Chen, J; Chen, X; Gao, W; Hao, B; Huang, M; Huang, W; Li, K; Liu, J; Liu, Q; Liu, R; Shao, Y; Wang, J; Wang, Q; Wei, Z; Xu, P; Xu, Y; Ye, S; Zeng, S; Zhang, H; Zhang, Q; Zhong, Z1
Fukusaki, E; Hori, Y; Ikeda, JI; Kawasaki, K; Kurashige, M; Morii, E; Nojima, S; Ohshima, K; Okuzaki, D; Tahara, S; Taniguchi, M; Umakoshi, Y; Wada, N1
Badur, MG; Cordes, T; Gengatharan, J; Handzlik, MK; Kolar, MJ; Lim, EW; Metallo, CM; Muthusamy, T; Pinto, AFM; Saghatelian, A; Wallace, M; You, L1
Arai, M; Chihara, T; Harada, K; Hayasaka, Y; Ishida, K; Ishihara, T; Kitaguchi, T; Matsumoto, M; Mita, M; Takizawa, M; Tsuboi, T; Tsuno, S; Ueda, H1
Altea-Manzano, P; Broekaert, D; Doglioni, G; Fendt, SM; Funk, CM; Geldhof, V; Grünewald, TGP; Hunter, KW; Lunt, SY; Planque, M; Pranzini, E; Rinaldi, G; Ross, C; Rossi, M; Teoh, ST; Van Elsen, J1
Li, Y; Ping, Q; Wang, S1
Bamidele, A; Brannon, JR; Codreanu, SG; Hadjifrangiskou, M; McLean, JA; Schrimpe-Rutledge, AC; Sherrod, SD; Steiner, BD; Wiebe, MA1
Holeček, M1

Reviews

2 review(s) available for pyruvic acid and serine

ArticleYear
[Synaptic regulation by astrocytes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2011, Volume: 138, Issue:4

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Glutamic Acid; Glycogen; Humans; Lactates; Neurons; Neurotransmitter Agents; Pyruvic Acid; Rats; Receptors, Neurotransmitter; Serine; Synaptic Transmission

2011
Role of Impaired Glycolysis in Perturbations of Amino Acid Metabolism in Diabetes Mellitus.
    International journal of molecular sciences, 2023, Jan-15, Volume: 24, Issue:2

    Topics: Amino Acids; Amino Acids, Branched-Chain; Diabetes Mellitus, Type 2; Glycine; Glycolysis; Humans; Pyruvic Acid; Serine

2023

Other Studies

67 other study(ies) available for pyruvic acid and serine

ArticleYear
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
Mechanism of L-serine oxidation in Entamoeba histolytica.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1979, Volume: 62, Issue:3

    Topics: Acetyl Coenzyme A; Ammonia; Animals; Entamoeba histolytica; L-Serine Dehydratase; Oxidation-Reduction; Oxygen Consumption; Pyruvate Oxidase; Pyruvates; Pyruvic Acid; Serine

1979
Possible involvement of alanine and pyruvate in the regulation of glucose transport in heart muscle cells.
    FEBS letters, 1990, Nov-12, Volume: 274, Issue:1-2

    Topics: Alanine; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Deoxyglucose; Female; Heart; Kinetics; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine; Valine

1990
Serine:glyoxylate aminotransferase from the seedlings of rye (Secale cereale L.).
    Acta biochimica Polonica, 1990, Volume: 37, Issue:2

    Topics: Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glyoxylates; Hydrogen-Ion Concentration; Mercaptoethanol; Molecular Weight; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Secale; Seeds; Serine; Substrate Specificity; Sucrose; Transaminases

1990
The biochemical basis for the distinction between the two Cryptococcus neoformans varieties with CGB medium.
    Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1986, Volume: 261, Issue:4

    Topics: Biological Transport; Bromthymol Blue; Canavanine; Cryptococcus; Cryptococcus neoformans; Culture Media; Glycine; Pyruvates; Pyruvic Acid; Serine

1986
Solid-state NMR studies of regulation of N-(phosphonomethyl)glycine and glycine metabolism in Pseudomonas sp. strain PG2982.
    The Journal of biological chemistry, 1987, Feb-05, Volume: 262, Issue:4

    Topics: Ammonia; Carbon; Glycine; Glyphosate; Magnetic Resonance Spectroscopy; Nitrogen; Pseudomonas; Pyruvates; Pyruvic Acid; Serine

1987
Gluconeogenesis from serine in rabbit hepatocytes.
    Archives of biochemistry and biophysics, 1987, Aug-15, Volume: 257, Issue:1

    Topics: Animals; Cells, Cultured; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; NAD; Pyruvates; Pyruvic Acid; Rabbits; Serine; Urea

1987
Pyruvate participation in the low molecular weight trophic activity for central nervous system neurons in glia-conditioned media.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:1

    Topics: Animals; Brain; Cell Survival; Cells, Cultured; Chick Embryo; Culture Media; Diencephalon; Hippocampus; Iron; Molecular Weight; Neuroglia; Neurons; Pyruvates; Pyruvic Acid; Rats; Septum Pellucidum; Serine; Telencephalon

1985
A mutation in Escherichia coli K-12 results in a requirement for thiamine and a decrease in L-serine deaminase activity.
    Journal of bacteriology, 1985, Volume: 161, Issue:1

    Topics: beta-Galactosidase; Drug Resistance, Microbial; Escherichia coli; Glycine; L-Serine Dehydratase; Leucine; Pyruvates; Pyruvic Acid; Serine; Thiamine; Transduction, Genetic

1985
Pyruvoyl-dependent histidine decarboxylases. Mechanism of cleavage of the proenzyme from Lactobacillus buchneri.
    The Journal of biological chemistry, 1985, Mar-10, Volume: 260, Issue:5

    Topics: Amino Acid Sequence; Carboxy-Lyases; Enzyme Precursors; Histidine Decarboxylase; Lactobacillus; Mass Spectrometry; Pyridoxamine; Pyruvates; Pyruvic Acid; Serine

1985
Kidney independent serine synthesis in the rat. Effect of dietary serine and glycine restriction.
    Nephron, 1985, Volume: 40, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Citrates; Citric Acid; Female; Glycine; Hydroxybutyrates; Ketoglutaric Acids; Kidney; Lactates; Male; Nephrectomy; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Serine

1985
Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources.
    Journal of bacteriology, 1983, Volume: 154, Issue:3

    Topics: Acetates; Amino Acids; Carboxylic Acids; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Legionella; Oxygen Consumption; Pentosephosphates; Pyruvates; Pyruvic Acid; Serine; Threonine

1983
Precursor of carbon atom five and hydroxymethyl carbon atom of the pyrimidine moiety of thiamin in Escherichia coli.
    Journal of nutritional science and vitaminology, 1983, Volume: 29, Issue:4

    Topics: Alanine; Escherichia coli; Glycerol; Pyrimidines; Pyruvates; Pyruvic Acid; Ribonucleotides; Serine; Thiamine

1983
Chemically defined requirements for the survival of cultured 8-day chick embryo ciliary ganglion neurons.
    Brain research, 1984, Jun-08, Volume: 302, Issue:2

    Topics: Animals; Cell Survival; Chick Embryo; Ciliary Neurotrophic Factor; Culture Media; Ganglia, Parasympathetic; Iron; Nerve Tissue Proteins; Neurons; Pyruvates; Pyruvic Acid; Serine

1984
Selective metabolism of L-serine by Moniliformis (Acanthocephala) in vitro.
    Parasitology, 1984, Volume: 89 ( Pt 1)

    Topics: Acanthocephala; Amino Acids; Animals; Carbon Dioxide; Cystathionine; Energy Metabolism; Ethanol; Female; Glucose; Male; Moniliformis; Pyruvates; Pyruvic Acid; Rats; Serine

1984
A novel reaction of the coenzyme of glutamate decarboxylase with L-serine O-sulfate.
    Biochemistry, 1982, Aug-31, Volume: 21, Issue:18

    Topics: Carboxy-Lyases; Chemical Phenomena; Chemistry; Escherichia coli; Glutamate Decarboxylase; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Serine; Spectrophotometry

1982
2-Methyl-L-tryptophan is a substrate of tryptophanase.
    Biochemistry and molecular biology international, 1995, Volume: 35, Issue:5

    Topics: Absorption; Deuterium; Escherichia coli; Indoles; Ions; Kinetics; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Serine; Substrate Specificity; Tryptophan; Tryptophanase

1995
Tests of the ability of two-cell mouse embryos to utilize selected precursors of phosphoenolpyruvic acid and pyruvic acid.
    The Journal of experimental zoology, 1993, Nov-15, Volume: 267, Issue:4

    Topics: Alanine; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Energy Metabolism; Female; Glyceric Acids; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Serine

1993
Microdialysis of human breast tissue during the menstrual cycle.
    Clinical science (London, England : 1979), 1997, Volume: 92, Issue:5

    Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine

1997
Processing of mammalian and plant S-adenosylmethionine decarboxylase proenzymes.
    The Journal of biological chemistry, 1997, Nov-07, Volume: 272, Issue:45

    Topics: Adenosylmethionine Decarboxylase; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Enzyme Precursors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Putrescine; Pyruvic Acid; Serine; Solanum tuberosum; Structure-Activity Relationship; Threonine

1997
Substrate inhibition of D-amino acid transaminase and protection by salts and by reduced nicotinamide adenine dinucleotide: isolation and initial characterization of a pyridoxo intermediate related to inactivation.
    Biochemistry, 1998, Mar-03, Volume: 37, Issue:9

    Topics: Alanine; Catalysis; Chromatography, High Pressure Liquid; D-Alanine Transaminase; Enzyme Inhibitors; NAD; Pyridoxal Phosphate; Pyridoxamine; Pyruvic Acid; Salts; Serine; Transaminases

1998
A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: inhibition of D-serine synthesis by converting serine racemase into an eliminase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Ammonia; Animals; Astrocytes; Cell Line; Cells, Cultured; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Mice; Pyruvic Acid; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Stereoisomerism; Substrate Specificity

2001
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
    Biochemistry, 2001, Jun-26, Volume: 40, Issue:25

    Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase

2001
Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis.
    Biochimica et biophysica acta, 2002, Apr-22, Volume: 1554, Issue:1-2

    Topics: Adenosine Triphosphate; Amino Acid Substitution; Arabidopsis; Catalysis; Cysteine; Dimerization; Enzyme Activation; Escherichia coli; Glutamic Acid; Glyoxylates; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Oxidoreductases; Oxygen; Plant Proteins; Protein Conformation; Pyruvic Acid; Sequence Analysis, DNA; Serine; Structure-Activity Relationship; Succinic Acid; Water

2002
A mutation in the folA promoter delays adaptation to minimal medium by Escherichia coli K-12.
    Journal of basic microbiology, 2002, Volume: 42, Issue:3

    Topics: Adaptation, Physiological; Culture Media; Escherichia coli; Mutation; Promoter Regions, Genetic; Pyruvic Acid; Serine; Temperature; Tetrahydrofolate Dehydrogenase; Valine

2002
Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Oct-29, Volume: 99, Issue:22

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Line; Humans; Ligands; Magnesium; Mice; Pyruvic Acid; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Serine

2002
Mouse brain serine racemase catalyzes specific elimination of L-serine to pyruvate.
    FEBS letters, 2003, Jan-30, Volume: 535, Issue:1-3

    Topics: Animals; Brain; Catalysis; Cations, Divalent; Cell Line; Dimerization; Enzyme Activation; Kinetics; Mice; Pyruvic Acid; Racemases and Epimerases; Recombinant Proteins; Serine; Substrate Specificity

2003
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levels.
    Microbiology (Reading, England), 2003, Volume: 149, Issue:Pt 8

    Topics: 2,6-Dichloroindophenol; Alanine; Amino Acids; Ammonia; Gastric Juice; Helicobacter pylori; Humans; In Vitro Techniques; Oxidation-Reduction; Oxygen Consumption; Proline; Pyruvic Acid; Serine; Stereoisomerism

2003
Contributions to silkworm biochemistry. VIII. Conversion of pyruvate into alanine, glycine and serine of silkfibroin.
    Archives internationales de physiologie et de biochimie, 1959, Volume: 67

    Topics: Alanine; Animals; Bombyx; Fabaceae; Glycine; Proteins; Pyruvates; Pyruvic Acid; Serine

1959
[NON-ENZYMIC SYNTHESIS OF CYSTEIC ACID FROM SOME BETA-SUBSTITUTED AMINO ACIDS, PYRUVATE, SULPHITE, AND COPPER IONS].
    Biochimica et biophysica acta, 1963, Oct-08, Volume: 78

    Topics: Amino Acid Substitution; Amino Acids; Catalysis; Chelating Agents; Chemical Phenomena; Chemistry; Copper; Cysteic Acid; Cysteine; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Research; Serine; Sulfites; Sulfur

1963
The formation of serine from pyruvate.
    The Journal of biological chemistry, 1955, Volume: 215, Issue:1

    Topics: Pyruvates; Pyruvic Acid; Serine

1955
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects.
    Chemical research in toxicology, 2003, Volume: 16, Issue:10

    Topics: Animals; Dose-Response Relationship, Drug; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Necrosis; Phosphorus Isotopes; Pyruvic Acid; Rats; Rats, Wistar; Serine; Time Factors; Urine

2003
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
    Biochemistry, 2004, Feb-24, Volume: 43, Issue:7

    Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine

2004
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
    Microbiology (Reading, England), 2004, Volume: 150, Issue:Pt 9

    Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine

2004
Regulation of serine racemase activity by amino acids.
    Brain research. Molecular brain research, 2005, Feb-18, Volume: 133, Issue:2

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Activation; Mice; Mice, Inbred C57BL; Pyruvic Acid; Racemases and Epimerases; Serine; Time Factors

2005
Mechanistic pathways of formation of acrylamide from different amino acids.
    Advances in experimental medicine and biology, 2005, Volume: 561

    Topics: Acrylamide; Acrylamides; Acrylates; Amino Acids; Ammonia; Asparagine; Aspartic Acid; beta-Alanine; Carbohydrates; Carnosine; Creatine; Cysteine; Fructose; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Models, Chemical; Pyruvic Acid; Serine; Time Factors

2005
Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae.
    Analytical biochemistry, 2007, Dec-15, Volume: 371, Issue:2

    Topics: Alanine Racemase; Chromatography, High Pressure Liquid; Humans; Hydro-Lyases; L-Lactate Dehydrogenase; NAD; Pyruvic Acid; Saccharomyces cerevisiae; Serine; Serum Albumin, Bovine; Spectrophotometry; Stereoisomerism

2007
Degradation of serine-containing oligopeptides by Peptostreptococcus micros ATCC 33270.
    Oral microbiology and immunology, 2007, Volume: 22, Issue:6

    Topics: Acetate Kinase; Acetates; Acetyltransferases; Adenosine Triphosphate; Ammonia; Formate Dehydrogenases; Formates; Humans; L-Serine Dehydratase; Oligopeptides; Peptostreptococcus; Phosphate Acetyltransferase; Pyruvate Synthase; Pyruvic Acid; Serine; Tyrosine

2007
YjgF is required for isoleucine biosynthesis when Salmonella enterica is grown on pyruvate medium.
    Journal of bacteriology, 2008, Volume: 190, Issue:8

    Topics: Bacterial Proteins; Biosynthetic Pathways; Gene Deletion; Glucose; Isoleucine; Models, Biological; Pyruvic Acid; Salmonella typhimurium; Serine; Suppression, Genetic; Threonine Dehydratase; Transaminases

2008
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells.
    Biochemical and biophysical research communications, 2009, Jan-23, Volume: 378, Issue:4

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Line; Glucose; Humans; Muscles; Niacinamide; Oxidation-Reduction; Phosphorylation; Pyruvic Acid; Quercetin; Rats; Resveratrol; Serine; Sirtuin 1; Sirtuins; Stilbenes; Threonine

2009
Tryptophan synthase: structure and function of the monovalent cation site.
    Biochemistry, 2009, Nov-24, Volume: 48, Issue:46

    Topics: Binding Sites; Biocatalysis; Cations, Monovalent; Cesium; Computer Simulation; Glycerophosphates; Histidine; Indoles; Kinetics; Models, Chemical; Models, Molecular; Protein Conformation; Pyruvic Acid; Quaternary Ammonium Compounds; Salmonella typhimurium; Serine; Sodium; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan Synthase

2009
D-Serine metabolism in C6 glioma cells: Involvement of alanine-serine-cysteine transporter (ASCT2) and serine racemase (SRR) but not D-amino acid oxidase (DAO).
    Journal of neuroscience research, 2010, Volume: 88, Issue:8

    Topics: Amino Acid Transport System ASC; Animals; Cell Line, Tumor; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioma; Minor Histocompatibility Antigens; Proline; Pyruvic Acid; Racemases and Epimerases; Rats; RNA Interference; RNA, Messenger; Serine; Tritium

2010
Fatal cerebral edema associated with serine deficiency in CSF.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Biomarkers; Blood Glucose; Brain; Brain Edema; Child; Child, Preschool; Energy Metabolism; Fatal Outcome; Female; Humans; Ketone Bodies; Lactic Acid; Neurotoxicity Syndromes; Predictive Value of Tests; Pyruvic Acid; Serine

2010
Rapid determination of free D-serine with chicken D-serine dehydratase.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-01, Volume: 879, Issue:29

    Topics: Animals; Bombyx; Chickens; Chromatography, High Pressure Liquid; Colorimetry; Enzyme Assays; Hydro-Lyases; Larva; Linear Models; Organ Specificity; Pyridoxal Phosphate; Pyruvic Acid; Serine

2011
Metabolic engineering and flux analysis of Corynebacterium glutamicum for L-serine production.
    Science China. Life sciences, 2012, Volume: 55, Issue:4

    Topics: Bacterial Proteins; Bioreactors; Corynebacterium glutamicum; Fermentation; Gene Expression Regulation, Bacterial; Glucose; Glycine; Glycine Hydroxymethyltransferase; Glycolysis; Metabolic Engineering; Pentose Phosphate Pathway; Phosphoglycerate Dehydrogenase; Phosphoglycerate Kinase; Pyruvic Acid; Serine

2012
Variable carbon catabolism among Salmonella enterica serovar Typhi isolates.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Carbon; Carboxylic Acids; Cluster Analysis; Glycerol; Glycerophosphates; Lactic Acid; Metabolome; Nucleosides; Phenotype; Pyruvic Acid; Salmonella typhi; Serine

2012
Kinetic evidence of a noncatalytic substrate binding site that regulates activity in Legionella pneumophila L-serine dehydratase.
    Biochemistry, 2012, Sep-04, Volume: 51, Issue:35

    Topics: Binding Sites; Computer Simulation; Kinetics; L-Serine Dehydratase; Legionella pneumophila; Models, Biological; Protein Conformation; Protein Structure, Tertiary; Pyruvic Acid; Serine; Substrate Specificity

2012
Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
    Nature, 2012, Nov-15, Volume: 491, Issue:7424

    Topics: Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Enzyme Activators; Glucose; Glycine; Humans; Ligands; Pyruvate Kinase; Pyruvic Acid; Recombinant Proteins; Serine

2012
Catabolism of serine by Pediococcus acidilactici and Pediococcus pentosaceus.
    Applied and environmental microbiology, 2013, Volume: 79, Issue:4

    Topics: Cheese; Cloning, Molecular; Diacetyl; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; L-Serine Dehydratase; Pediococcus; Pyruvic Acid; Recombinant Proteins; Serine; Sodium Chloride

2013
Significance of the D-serine-deaminase and D-serine metabolism of Staphylococcus saprophyticus for virulence.
    Infection and immunity, 2013, Volume: 81, Issue:12

    Topics: Ammonia; Animals; Female; Hydro-Lyases; Mice; Mice, Inbred C3H; Pyruvic Acid; Serine; Staphylococcal Infections; Staphylococcus saprophyticus; Urinary Tract Infections; Virulence Factors

2013
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
    Disease markers, 2013, Volume: 35, Issue:5

    Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophosphates; Lactic Acid; Liver; Male; Metabolome; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine

2013
Metabolic responses of CHO cells to limitation of key amino acids.
    Biotechnology and bioengineering, 2014, Volume: 111, Issue:10

    Topics: Amino Acids; Animals; Asparagine; Cell Culture Techniques; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Gas Chromatography-Mass Spectrometry; Glutamate-Ammonia Ligase; Magnetic Resonance Spectroscopy; Pyruvic Acid; Serine

2014
Major contribution of the type II beta carbonic anhydrase CanB (Cj0237) to the capnophilic growth phenotype of Campylobacter jejuni.
    Environmental microbiology, 2016, Volume: 18, Issue:2

    Topics: Aspartic Acid; Bicarbonates; Campylobacter jejuni; Carbon Dioxide; Carbonic Anhydrase II; Culture Media; Lactic Acid; Oxaloacetic Acid; Oxygen; Phenotype; Pyruvate Carboxylase; Pyruvic Acid; Serine

2016
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
    Molecular cell, 2015, Oct-15, Volume: 60, Issue:2

    Topics: Adaptation, Physiological; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glucose; Glutamine; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Mitochondria; Neoplasms; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (ATP); Purines; Pyruvic Acid; Serine

2015
Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
    The Journal of biological chemistry, 2016, Mar-18, Volume: 291, Issue:12

    Topics: Alcohol Oxidoreductases; Carbohydrate Metabolism; Gene Expression; Glutarates; Ketoglutarate Dehydrogenase Complex; Kinetics; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Oxaloacetic Acid; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity

2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine

2017
A Synthetic Alternative to Canonical One-Carbon Metabolism.
    ACS synthetic biology, 2017, 08-18, Volume: 6, Issue:8

    Topics: Acetoacetates; Carbon; Escherichia coli; Escherichia coli Proteins; Genetic Enhancement; Glycine; Metabolic Engineering; Metabolic Networks and Pathways; Pyruvic Acid; Serine; Synthetic Biology

2017
Catabolite repression in Campylobacter jejuni correlates with intracellular succinate levels.
    Environmental microbiology, 2018, Volume: 20, Issue:4

    Topics: Bacterial Proteins; Campylobacter jejuni; Carbon; Catabolite Repression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Lactic Acid; Pyruvic Acid; Serine; Succinic Acid; Transcription Factors

2018
Electrical-biological hybrid system for CO
    Metabolic engineering, 2018, Volume: 47

    Topics: Carbon Dioxide; Escherichia coli; Formates; Glycine; Metabolic Engineering; Microorganisms, Genetically-Modified; Oxidation-Reduction; Pyruvic Acid; Serine

2018
Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect.
    Nature communications, 2019, 12-05, Volume: 10, Issue:1

    Topics: Animals; Aurora Kinase A; Azepines; Cell Line, Tumor; Glycolysis; HEK293 Cells; HeLa Cells; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasms; Phosphorylation; Pyrimidines; Pyruvic Acid; Serine; Substrate Specificity; Tumor Burden; Xenograft Model Antitumor Assays

2019
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
    Cell death & disease, 2020, 05-04, Volume: 11, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Female; Glutamine; Glycolysis; Heterocyclic Compounds; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Docking Simulation; NAD; Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Serine; Spin Labels; Xenograft Model Antitumor Assays

2020
Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine.
    Nature metabolism, 2020, Volume: 2, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Heterografts; Humans; Mice; Mice, Nude; Pyruvic Acid; Racemases and Epimerases; RNA, Messenger; Serine; Up-Regulation

2020
Serine restriction alters sphingolipid diversity to constrain tumour growth.
    Nature, 2020, Volume: 586, Issue:7831

    Topics: Alanine; Animals; Cell Adhesion; Cell Division; Diet; Female; Glycine; HCT116 Cells; Humans; Membrane Lipids; Mice; Mitochondria; Neoplasms; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Serine; Serine C-Palmitoyltransferase; Spheroids, Cellular; Sphingolipids; Stress, Physiological; Xenograft Model Antitumor Assays

2020
Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.
    Scientific reports, 2020, 11-11, Volume: 10, Issue:1

    Topics: Animals; Biosensing Techniques; Cells, Cultured; Female; Glycolysis; Green Fluorescent Proteins; HeLa Cells; Humans; Lactic Acid; Mice, Inbred ICR; Molecular Imaging; Myocytes, Cardiac; Neurons; Oligomycins; Pregnancy; Pyruvic Acid; Recombinant Proteins; Serine

2020
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
    Molecular cell, 2021, 01-21, Volume: 81, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ketoglutaric Acids; Lung Neoplasms; Mammary Neoplasms, Experimental; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred BALB C; Mice, Nude; Monocarboxylic Acid Transporters; Phosphoglycerate Dehydrogenase; Pyruvic Acid; RNA, Small Interfering; Serine; Signal Transduction; Sirolimus

2021
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
    Chemosphere, 2022, Volume: 297

    Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine

2022
Serine Deamination Is a New Acid Tolerance Mechanism Observed in Uropathogenic Escherichia coli.
    mBio, 2022, 12-20, Volume: 13, Issue:6

    Topics: Deamination; Escherichia coli Proteins; Female; Humans; L-Serine Dehydratase; Membrane Transport Proteins; Pyruvic Acid; Serine; Uropathogenic Escherichia coli

2022