pyruvic acid and leucine

pyruvic acid has been researched along with leucine in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (34.25)	18.7374
1990's	9 (12.33)	18.2507
2000's	17 (23.29)	29.6817
2010's	16 (21.92)	24.3611
2020's	6 (8.22)	2.80

Authors

Authors	Studies
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H	1
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H	1
Arch, JE; Stanko, RT; Tietze, DL	2
Eizirik, DL; Sandler, S	1
Blanco, A; Burgos, C; Coronel, CE; Gallina, FG; Gerez de Burgos, NM	1
Carpinelli, AR; Dufrane, SP; Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Mathias, PC; Sener, A; Valverde, I	1
Grootegoed, JA; Jansen, R; Oonk, RB; van der Molen, HJ	1
Malvoisin, E; Wild, F; Zwingelstein, G	1
Erecinska, M; Wilson, DF; Zaleski, J	1
Chua, BH; Kleinhans, BJ	1
Agius, L; Alberti, KG; Battersby, C	1
Colebrook, LD; Miller, B; Newman, EB; Walker, C	1
Radeck, W; Schadewaldt, P; Staib, W	1
Hodson, R; K'nees, E; Kirchman, D	1
Aftring, RP; Buse, MG; Manos, PN	1
Glatz, JF; van Moerkerk, HT; Veerkamp, JH; Wagenmakers, AJ	1
Malaisse, WJ	1
Hellerström, C; Herchuelz, A; Lebrun, P; Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Welsh, M	1
Dufrane, SP; Malaisse, WJ; Malaisse-Lagae, F; Sener, A	1
Casanello-Ertl, D; Duducgian-Vartavarian, L; Pardridge, WM	1
Charon, NW; Peterson, DE; Westfall, HN	1
Agius, L; Alberti, KG; Wilding, C	1
Barron, LL; Buxton, DB; Olson, MS; Taylor, MK	1
Oelers, R; Radeck, W; Schadewaldt, P; Staib, W	1
Odessey, R; Parr, B	1
Malaisse, WJ; Malaisse-Lagae, F; Sener, A	1
Fagan, JM; Tischler, ME	1
D'Alessandro, AM; Salustri, A	1
King, J; Mourad, G; Williams, D	1
Chua, BH	1
Argilés, JM; Domènech, M; López-Soriano, FJ	1
Gossain, S; Palmer, TN; Sugden, MC	1
Cocaign-Bousquet, M; Ehrlich, SD; Godon, JJ; Goupil-Feuillerat, N; Renault, P	1
Leighton, B; Young, ME	1
Cass, CE; Cheeseman, CI; Muzyka, WR; Yao, SY; Young, JD	1
Antinozzi, PA; Hagenfeldt, KA; Maechler, P; Wang, H; Wollheim, CB	1
Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP	1
Glushka, JN; Whitman, WB; Yang, YL	1
Bruschi, SA; Conway, M; Cooper, AJ; Hutson, SM	1
Ceresoli-Borroni, G; Guidetti, P; Kiss, C; Schwarcz, R; Zielke, CL; Zielke, HR	1
Beck, HC; Hansen, AM; Lauritsen, FR	1
Chiao, J; Guo, X; Jiang, W; Ren, S; Staempfli, AA; Xu, H; Zhang, Y; Zhao, G	1
Cline, GW; Kibbey, RG; Lepine, RL; Papas, KK; Shulman, GI	1
Chaudhary, LC; McKain, N; Miyagawa, E; Walker, ND; Wallace, RJ	1
Kay, LE; Tugarinov, V	1
Bretin, S; Gauchy, C; Glowinski, J; Maus, M; Nairn, AC; Premont, J; Torrens, Y	1
Agascioglu, E; Giroix, MH; Malaisse, WJ; Sener, A	1
Bathe, B; Blombach, B; Eikmanns, BJ; Hans, S	1
Baldwin, RL; Bequette, BJ; El-Kadi, SW; McLeod, KR; Sunny, NE	1
Cline, GW; Kibbey, RG; Kirkpatrick, CL; Pongratz, RL; Pontoglio, M; Shulman, GI; Wollheim, CB; Yaniv, M; Zhao, X	1
Cerdan, S; Contreras, L; Garzón, M; Kobayashi, K; Llorente-Folch, I; Pardo, B; Rodrigues, TB; Saheki, T; Satrústegui, J	1
Herzig, S; Kunji, ER; Martinou, JC; Montessuit, S; Raemy, E; Veuthey, JL; Westermann, B; Zamboni, N	1
A, J; Cao, B; Di, L; Liu, L; Tu, J; Wang, A; Wang, G; Wen, H	1
Bouchard, B; Des Rosiers, C; Isern, N; Kajimoto, M; Ledee, DR; Olson, AK; Portman, MA; Priddy, CM	1
Campos, AG; de Franceschi, ID; Feksa, LR; Rech, VC; Rieger, E; Rojas, DB; Vargas, AP; Wannmacher, CM	1
Becker, S; Demers, JP; Faßhuber, HK; Giller, K; Lange, A; Loquet, A; Lv, G; Vijayan, V	1
Allard, P; Alvarez, F; Gauthier, N; Kratz, L; Lépine, F; Mamer, OA; Mitchell, GA; Moser, AB; Robitaille, Y; Sweetman, L; Wang, SP; Wu, JW	1
Fukuoka, H; Imamura, H; Inagaki, N; Kakizuka, A; Kioka, H; Nagashima, K; Noji, H; Takashima, S; Tanaka, T	1
Hasan, NM; Kendrick, MA; Longacre, MJ; MacDonald, MJ; Stoker, SW	1
Das, P; Dwivedi, SN; Gupta, SD; Jagannathan, NR; Makharia, GK; Mewar, S; Mishra, A; Sharma, U; Upadhyay, D	1
Des Rosiers, C; Isern, N; Kajimoto, M; Ledee, DR; O'Kelly Priddy, CM; Olson, AK; Portman, MA; Robillard-Frayne, I	1
Fang, B; Jiang, W; Lu, J; Sun, D; Wang, S; Zhang, Y	1
Fang, BS; Jiang, SZ; Jiang, W; Wang, SZ; Xu, CZ; Zhang, TD	1
de Franceschi, ID; Preissler, T; Rieger, E; Wannmacher, CMD	1
Glaser, RW; Hunt, JF; Jouhten, P; Maaheimo, H; Montelione, GT; Swapna, GVT; Szyperski, T; Xu, Y; Yu, XW; Zhang, M	1
Li, Y; Wang, C; Wang, X; Zhang, H	1
Fujita, Y; Ijiri, D; Kawaguchi, M; Kohrogi, R; Nishikoba, N; Ohtsuka, A; Shimamoto, S; Tomonaga, S; Yamauchi, Y	1
Picklo, MJ; Rust, BM; Yan, L	1
Bezsudnova, EY; Boyko, KM; Popov, VO; Stekhanova, TN	1
Chen, P; Shi, K; Wang, YY; Xu, JZ; Zhang, F; Zhang, WG	1
Li, Y; Ping, Q; Wang, S	1
Ghaeidamini, M; Gholaminejad, A; Hudkins, KL; Roointan, A; Shafieizadegan, S	1

Reviews

2 review(s) available for pyruvic acid and leucine

Article	Year
Insulin release : the fuel concept. Diabete & metabolisme, 1983, Volume: 9, Issue:4 Topics: Amino Acids; Caproates; Energy Metabolism; Glucose-6-Phosphate; Glucosephosphates; Glycolysis; Hexoses; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Models, Biological; Norleucine; Phenylpyruvic Acids; Pyruvates; Pyruvic Acid; Stereoisomerism; Structure-Activity Relationship	1983
Metabolome panels as potential noninvasive biomarkers for primary glomerulonephritis sub-types: meta-analysis of profiling metabolomics studies. Scientific reports, 2023, Nov-21, Volume: 13, Issue:1 Topics: Biomarkers; Choline; Glomerulonephritis; Humans; Leucine; Metabolome; Metabolomics; Pyruvic Acid	2023

Article

Year

Insulin release : the fuel concept.

Diabete & metabolisme, 1983, Volume: 9, Issue:4

Topics: Amino Acids; Caproates; Energy Metabolism; Glucose-6-Phosphate; Glucosephosphates; Glycolysis; Hexoses; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Models, Biological; Norleucine; Phenylpyruvic Acids; Pyruvates; Pyruvic Acid; Stereoisomerism; Structure-Activity Relationship

1983

Metabolome panels as potential noninvasive biomarkers for primary glomerulonephritis sub-types: meta-analysis of profiling metabolomics studies.

Scientific reports, 2023, Nov-21, Volume: 13, Issue:1

Topics: Biomarkers; Choline; Glomerulonephritis; Humans; Leucine; Metabolome; Metabolomics; Pyruvic Acid

2023

Trials

1 trial(s) available for pyruvic acid and leucine

Article	Year
Body composition, energy utilization, and nitrogen metabolism with a 4.25-MJ/d low-energy diet supplemented with pyruvate. The American journal of clinical nutrition, 1992, Volume: 56, Issue:4 Topics: Body Composition; Diet, Reducing; Energy Intake; Energy Metabolism; Female; Humans; Leucine; Nitrogen; Obesity; Pyruvates; Pyruvic Acid; Weight Loss	1992

Other Studies

70 other study(ies) available for pyruvic acid and leucine

Article	Year
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20 Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis	2001
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics, 2002, Volume: 79, Issue:1 Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis	2002
Body composition, energy utilization, and nitrogen metabolism with a severely restricted diet supplemented with dihydroxyacetone and pyruvate. The American journal of clinical nutrition, 1992, Volume: 55, Issue:4 Topics: Adult; Basal Metabolism; Body Composition; Diet, Reducing; Dihydroxyacetone; Energy Metabolism; Female; Humans; Leucine; Middle Aged; Nitrogen; Obesity; Pyruvates; Pyruvic Acid; Weight Loss	1992
Human interleukin-1 beta induced stimulation of insulin release from rat pancreatic islets is accompanied by an increase in mitochondrial oxidative events. Diabetologia, 1989, Volume: 32, Issue:11 Topics: Animals; Cells, Cultured; Glucose; Glutamine; Glycolysis; Humans; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Leucine; Male; Mitochondria; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Recombinant Proteins	1989
Properties of the branched-chain 2-hydroxy acid/2-oxo acid shuttle in mouse spermatozoa. The Biochemical journal, 1986, May-01, Volume: 235, Issue:3 Topics: Animals; Biological Transport; Glutamates; Glutamic Acid; Hydroxy Acids; In Vitro Techniques; Keto Acids; Lactates; Lactic Acid; Leucine; Male; Mice; Mitochondria; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Spermatozoa; Tissue Distribution	1986
The coupling of metabolic to secretory events in pancreatic islets. The possible role of glutathione reductase. Biochimica et biophysica acta, 1985, Feb-21, Volume: 844, Issue:2 Topics: Animals; Calcium; Carmustine; Cyclic AMP; Glutamine; Glutathione; Glutathione Reductase; Insulin; Islets of Langerhans; Lactates; Lactic Acid; Leucine; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats	1985
Metabolism of radiolabelled energy-yielding substrates by rat Sertoli cells. Journal of reproduction and fertility, 1986, Volume: 77, Issue:1 Topics: Animals; Bucladesine; Cells, Cultured; Energy Metabolism; Follicle Stimulating Hormone; Glucose; Glutamine; Leucine; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells	1986
Relationship between membrane sterol composition and responsiveness to 12-O-tetradecanoylphorbol 13-acetate in HL-60 human promyelocytic leukaemia cell lines. The Biochemical journal, 1988, Mar-01, Volume: 250, Issue:2 Topics: Acetates; Carbon Radioisotopes; Cell Line; Cholesterol; Humans; Lanosterol; Leucine; Leukemia, Myeloid, Acute; Lipid Metabolism; Pyruvates; Pyruvic Acid; Sterols; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured	1988
Glutamine metabolism in rat hepatocytes. Stimulation by a nonmetabolizable analog of leucine. The Journal of biological chemistry, 1986, Oct-25, Volume: 261, Issue:30 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Amino Acids, Cyclic; Animals; Glucagon; Glutamine; Hydroxybutyrates; Ketoglutaric Acids; Leucine; Liver; Malates; Ornithine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea	1986
Effect of redox potential on protein degradation in perfused rat heart. The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 1 Topics: Animals; Glucose; Heart; Insulin; Leucine; Malates; Male; Myocardium; NAD; Oxidation-Reduction; Perfusion; Phenylalanine; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1985
Monolayer culture of parenchymal rat hepatocytes on collagen-coated microcarriers. A hepatocyte system for short- and long-term metabolic studies. In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:5 Topics: Animals; Blood; Calcium; Collagen; Culture Media; Culture Techniques; Dichloroacetic Acid; Fatty Acids; Glucose; Insulin; Leucine; Liver; Liver Glycogen; Magnesium; Male; Methods; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors	1985
A mutation in Escherichia coli K-12 results in a requirement for thiamine and a decrease in L-serine deaminase activity. Journal of bacteriology, 1985, Volume: 161, Issue:1 Topics: beta-Galactosidase; Drug Resistance, Microbial; Escherichia coli; Glycine; L-Serine Dehydratase; Leucine; Pyruvates; Pyruvic Acid; Serine; Thiamine; Transduction, Genetic	1985
Differential effect of dichloroacetate on branched-chain amino acid catabolism in perfused rat hindlimbs. FEBS letters, 1985, Apr-08, Volume: 183, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetates; Amino Acids, Branched-Chain; Animals; Carbon Dioxide; Dichloroacetic Acid; Hindlimb; Ketone Oxidoreductases; Leucine; Multienzyme Complexes; Muscles; Pyruvates; Pyruvic Acid; Rats; Valine	1985
Leucine incorporation and its potential as a measure of protein synthesis by bacteria in natural aquatic systems. Applied and environmental microbiology, 1985, Volume: 49, Issue:3 Topics: Bacterial Proteins; DNA, Bacterial; Leucine; Pyruvates; Pyruvic Acid; Water Microbiology	1985
Catabolism of branched-chain amino acids by diaphragm muscles of fasted and diabetic rats. Metabolism: clinical and experimental, 1985, Volume: 34, Issue:8 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amination; Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diaphragm; Fasting; In Vitro Techniques; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Muscles; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Transaminases; Valine	1985
Effect of clofibrate feeding on palmitate and branched-chain 2-oxo acid oxidation in rat liver and muscle. Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17 Topics: Animals; Citrate (si)-Synthase; Clofibrate; Electron Transport Complex IV; Keto Acids; Kinetics; Leucine; Liver; Male; Muscles; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1983
The stimulus-secretion coupling of amino acid-induced insulin release. Secretory and oxidative response of pancreatic islets to L-asparagine. Diabetes, 1984, Volume: 33, Issue:5 Topics: Amino Acids; Animals; Asparagine; Calcium; Drug Interactions; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Malates; Oxaloacetates; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Theophylline	1984
The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state. The Biochemical journal, 1984, Jun-01, Volume: 220, Issue:2 Topics: Animals; Cytosol; Glutamine; In Vitro Techniques; Islets of Langerhans; Isocitrate Dehydrogenase; Leucine; Malate Dehydrogenase; Malates; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats	1984
Effects of dichloroacetate on the lactate/pyruvate ratio and on aspartate and leucine metabolism in cultured rat skeletal muscle cells. Biochemical pharmacology, 1983, Jan-01, Volume: 32, Issue:1 Topics: Acetates; Animals; Aspartic Acid; Carbon Dioxide; Cells, Cultured; Culture Media; Dichloroacetic Acid; Lactates; Lactic Acid; Leucine; Male; Muscles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors	1983
Multiple pathways for isoleucine biosynthesis in the spirochete Leptospira. Journal of bacteriology, 1983, Volume: 154, Issue:2 Topics: Isoleucine; Leptospira; Leptospira interrogans; Leucine; Pyruvates; Pyruvic Acid; Threonine	1983
Metabolic effects of bacitracin in isolated rat hepatocytes. The Biochemical journal, 1983, Nov-15, Volume: 216, Issue:2 Topics: Adenine Nucleotides; Animals; Bacitracin; Carbon Dioxide; Cell Separation; In Vitro Techniques; Insulin; Ketone Bodies; Leucine; Liver; Male; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1983
Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart. The Biochemical journal, 1984, Aug-01, Volume: 221, Issue:3 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Caprylates; Decarboxylation; Glucose; Heart; In Vitro Techniques; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Myocardium; Palmitic Acid; Palmitic Acids; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1984
Oxidative determination of 14C-labeled 2-oxo acids. Analytical biochemistry, 1984, Volume: 143, Issue:2 Topics: Animals; Carbon Radioisotopes; Keto Acids; Lactates; Leucine; Muscles; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet	1984
Effect of insulin and leucine on protein turnover in rat soleus muscle after burn injury. Metabolism: clinical and experimental, 1982, Volume: 31, Issue:1 Topics: Adenosine Triphosphate; Animals; Atrophy; Burns; Insulin; Lactates; Lactic Acid; Leucine; Male; Muscles; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1982
The stimulus-secretion coupling of glucose-induced insulin release: effect of aminooxyacetate upon nutrient-stimulated insulin secretion. Endocrinology, 1982, Volume: 111, Issue:2 Topics: Acetates; Aminooxyacetic Acid; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; Malates; Pyruvates; Pyruvic Acid; Rats	1982
Relationship of the reduction-oxidation state to protein degradation in skeletal and atrial muscle. Archives of biochemistry and biophysics, 1982, Volume: 217, Issue:1 Topics: Animals; Diaphragm; Heart Atria; Lactates; Lactic Acid; Leucine; Malates; Male; Muscle Proteins; Muscles; NAD; Oxidation-Reduction; Protease Inhibitors; Pyruvates; Pyruvic Acid; Rats	1982
[Influence of follicular cells on energy metabolism of oocytes in growing mice]. Bollettino della Societa italiana di biologia sperimentale, 1982, Jul-30, Volume: 58, Issue:14 Topics: Animals; Energy Metabolism; Female; Glucose; Leucine; Mice; Oocytes; Ovarian Follicle; Ovary; Pyruvates; Pyruvic Acid	1982
A double mutant allele, csr1-4, of Arabidopsis thaliana encodes an acetolactate synthase with altered kinetics. Planta, 1995, Volume: 196, Issue:1 Topics: Acetolactate Synthase; Alleles; Arabidopsis; Isoleucine; Kinetics; Leucine; Mutation; Pyruvates; Pyruvic Acid; Valine	1995
Specificity of leucine effect on protein degradation in perfused rat heart. Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:6 Topics: Amino Alcohols; Animals; Cycloserine; Decarboxylation; Glucose; Heart; In Vitro Techniques; Keto Acids; Leucine; Male; Myocardium; Perfusion; Protein Biosynthesis; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley	1994
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats. Cellular and molecular biology (Noisy-le-Grand, France), 1993, Volume: 39, Issue:6 Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker	1993
Partial oxidation of leucine in skeletal muscle. Biochemistry and molecular biology international, 1993, Volume: 29, Issue:2 Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diaphragm; Eating; Glucose; Hydroxybutyrates; Keto Acids; Ketone Bodies; Lactates; Lactic Acid; Leucine; Male; Muscles; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar	1993
Dual role of alpha-acetolactate decarboxylase in Lactococcus lactis subsp. lactis. Journal of bacteriology, 1997, Volume: 179, Issue:20 Topics: Acetoin; Acetolactate Synthase; Amino Acid Sequence; Amino Acids, Branched-Chain; Bacterial Proteins; Base Sequence; Carboxy-Lyases; Genes, Bacterial; Isoleucine; Lactates; Lactococcus lactis; Leucine; Molecular Sequence Data; Promoter Regions, Genetic; Pyruvic Acid; Transcription, Genetic; Valine	1997
Fuel oxidation in skeletal muscle is increased by nitric oxide/cGMP--evidence for involvement of cGMP-dependent protein kinase. FEBS letters, 1998, Mar-06, Volume: 424, Issue:1-2 Topics: Aminoquinolines; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Glucose; Leucine; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitroprusside; Oxidation-Reduction; Palmitates; Pyruvic Acid; Rats; Rats, Wistar; Vasodilator Agents	1998
Evidence that the transport-related proteins BAT and 4F2hc are not specific for amino acids: induction of Na+-dependent uridine and pyruvate transport activity by recombinant BAT and 4F2hc expressed in Xenopus oocytes. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1998, Volume: 76, Issue:5 Topics: Animals; Antigens, CD; Bacterial Proteins; Carrier Proteins; Choline; Escherichia coli Proteins; Fusion Regulatory Protein-1; Leucine; Mice; Oocytes; Pyruvic Acid; Rats; Uridine; Xenopus	1998
Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion. The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46 Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxycycline; Gene Expression Regulation; Genes, Reporter; Glucose; Hepatocyte Nuclear Factor 4; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Membrane Potentials; Mitochondria; Phosphoproteins; Promoter Regions, Genetic; Pyruvic Acid; Rats; Recombinant Fusion Proteins; RNA, Messenger; Time Factors; Transcription Factors; Tumor Cells, Cultured	2000
Amino acid kinetics during the anhepatic phase of liver transplantation. Diabetes, 2002, Volume: 51, Issue:6 Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid	2002
Intracellular pyruvate flux in the methane-producing archaeon Methanococcus maripaludis. Archives of microbiology, 2002, Volume: 178, Issue:6 Topics: Alanine; Carbon Radioisotopes; Isoleucine; Leucine; Methane; Methanococcus; Oxidoreductases; Pyruvic Acid	2002
Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation. Biochemical pharmacology, 2003, Jan-15, Volume: 65, Issue:2 Topics: Ammonia; beta-Alanine; Carbon-Sulfur Lyases; Cysteine; Cytosol; Halogens; Humans; Hydrocarbons, Fluorinated; Keto Acids; Leucine; Mitochondria; Pyruvic Acid; Recombinant Proteins; Substrate Specificity; Temperature; Transaminases	2003
Kynurenate production by cultured human astrocytes. Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:1 Topics: Aminooxyacetic Acid; Astrocytes; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glycine; Humans; Immunohistochemistry; Kynurenic Acid; Kynurenine; Leucine; Neuroprotective Agents; Nicotine; Oxaloacetic Acid; Phenylalanine; Pyruvic Acid; Receptors, Nicotinic; Transaminases	2003
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. Journal of applied microbiology, 2004, Volume: 96, Issue:5 Topics: Cell Membrane; Chromatography; Culture Media; Fatty Acids; Flavoring Agents; Food Microbiology; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Meat Products; Oxidation-Reduction; Pentanoic Acids; Pyruvic Acid; Staphylococcus; Valine	2004
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway. Journal of bacteriology, 2004, Volume: 186, Issue:16 Topics: 2-Isopropylmalate Synthase; 3-Isopropylmalate Dehydrogenase; Adaptation, Physiological; Alcohol Oxidoreductases; Bacterial Proteins; Cloning, Molecular; Culture Media; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Hydro-Lyases; Isoleucine; Isomerases; Leptospira interrogans; Leucine; Methanococcus; Molecular Sequence Data; Mutation; Pyruvic Acid; Recombinant Proteins; RNA, Bacterial; RNA, Messenger; Sequence Analysis, DNA; Substrate Specificity; Threonine	2004
13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells. The Journal of biological chemistry, 2004, Oct-22, Volume: 279, Issue:43 Topics: Adenosine Triphosphate; Animals; Carbon; Carbon Isotopes; Cell Line; Citric Acid Cycle; Culture Media; Glucose; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Glycolysis; Humans; Insulin; Insulin Secretion; Leucine; Magnetic Resonance Spectroscopy; Models, Biological; Oxygen; Perfusion; Protons; Pyruvate Carboxylase; Pyruvic Acid; Rats; Time Factors	2004
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri. Microbiology (Reading, England), 2004, Volume: 150, Issue:Pt 9 Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine	2004
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface. Biochemistry, 2005, Dec-13, Volume: 44, Issue:49 Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine	2005
2-Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor-2 by distinct mechanisms. Journal of neurochemistry, 2006, Volume: 96, Issue:3 Topics: Animals; Antimetabolites; Blotting, Western; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Ionophores; Leucine; Mice; Models, Biological; N-Methylaspartate; Neurons; Oligomycins; Peptide Elongation Factor 2; Phosphorylation; Protein Kinases; Protein Synthesis Inhibitors; Pyruvic Acid; Sodium Azide; Time Factors; TOR Serine-Threonine Kinases; Tritium	2006
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues. Endocrine, 2006, Volume: 29, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Female; Galactose; Glucose; Glutamine; Glyceraldehyde; Islets of Langerhans; Keto Acids; Lactic Acid; Leucine; Mannose; Nutritional Physiological Phenomena; Pyruvic Acid; Rats; Rats, Wistar	2006
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum. Applied and environmental microbiology, 2009, Volume: 75, Issue:2 Topics: Acetolactate Synthase; Bacterial Proteins; Butyrates; Corynebacterium glutamicum; Enzyme Inhibitors; Gene Expression Profiling; Isoleucine; Kinetics; Leucine; Lysine; Pyruvic Acid; Sequence Deletion; Valine	2009
Glutamate is the major anaplerotic substrate in the tricarboxylic acid cycle of isolated rumen epithelial and duodenal mucosal cells from beef cattle. The Journal of nutrition, 2009, Volume: 139, Issue:5 Topics: Animals; Carbon Isotopes; Cattle; Citric Acid Cycle; Diet; Duodenum; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Glutamine; Intestinal Mucosa; Lactic Acid; Leucine; Male; Pyruvic Acid; Rumen; Valine	2009
Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets. The Journal of biological chemistry, 2009, Jun-19, Volume: 284, Issue:25 Topics: Adenosine Triphosphate; Animals; Base Sequence; Cell Line; Diabetes Mellitus, Type 2; DNA Primers; Female; Glucose; Glucose Transporter Type 2; Glutamine; Glycolysis; Hepatocyte Nuclear Factor 1-alpha; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Mice, Knockout; Mitochondria; Mutation; Oxidative Phosphorylation; Pyruvic Acid; Rats; RNA, Messenger	2009
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:1 Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid	2011
Identification and functional expression of the mitochondrial pyruvate carrier. Science (New York, N.Y.), 2012, Jul-06, Volume: 337, Issue:6090 Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Biosynthetic Pathways; Culture Media; Lactococcus lactis; Leucine; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Molecular Sequence Data; Monocarboxylic Acid Transporters; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thioctic Acid; Valine	2012
[Plasma metabonomics study of ischemic cerebral apoplexy rats treated with Tongsaimai pellets]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:7 Topics: Animals; Brain Ischemia; Drugs, Chinese Herbal; Fructose; Glyceric Acids; Hydroxyproline; Lactic Acid; Leucine; Male; Malonates; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Stroke; Taurine; Tryptophan	2012
Myocardial oxidative metabolism and protein synthesis during mechanical circulatory support by extracorporeal membrane oxygenation. American journal of physiology. Heart and circulatory physiology, 2013, Feb-01, Volume: 304, Issue:3 Topics: Acetyl Coenzyme A; Animals; Blood Pressure; Citric Acid Cycle; Extracorporeal Membrane Oxygenation; Gas Chromatography-Mass Spectrometry; Heart; Heart Rate; Hemoglobins; Interleukin-6; Leucine; Magnetic Resonance Spectroscopy; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Protein Biosynthesis; Pyruvic Acid; Swine	2013
Effect of leucine administration to female rats during pregnancy and lactation on oxidative stress and enzymes activities of phosphoryltransfer network in cerebral cortex and hippocampus of the offspring. Neurochemical research, 2013, Volume: 38, Issue:3 Topics: Animals; Antioxidants; Cerebral Cortex; Creatine; Female; Hippocampus; Lactation; Leucine; Male; Maple Syrup Urine Disease; Oxidative Stress; Phosphotransferases; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvic Acid; Rats; Rats, Wistar	2013
A straightforward method for stereospecific assignment of val and leu prochiral methyl groups by solid-state NMR: Scrambling in the [2-13C]Glucose labeling scheme. Journal of magnetic resonance (San Diego, Calif. : 1997), 2013, Volume: 228 Topics: Carbon Isotopes; Glucose; Glycolysis; Leucine; Nuclear Magnetic Resonance, Biomolecular; Pentose Phosphate Pathway; Protein Conformation; Pyruvic Acid; Ubiquitin; Valine	2013
A liver-specific defect of Acyl-CoA degradation produces hyperammonemia, hypoglycemia and a distinct hepatic Acyl-CoA pattern. PloS one, 2013, Volume: 8, Issue:7 Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Dioxide; Gene Knockout Techniques; Gene Order; Gene Targeting; Genes, Lethal; Gluconeogenesis; Hepatocytes; Humans; Hyperammonemia; Hypoglycemia; Lethargy; Leucine; Liver; Metabolic Networks and Pathways; Metabolome; Mice; Mice, Knockout; Mitochondria; Models, Biological; Peroxisomes; Phenotype; Pyruvic Acid	2013
Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations. The Journal of biological chemistry, 2014, Jan-24, Volume: 289, Issue:4 Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cytosol; Glucose; Glutamine; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Mitochondria; Pyruvic Acid; Sweetening Agents	2014
Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells. Molecular endocrinology (Baltimore, Md.), 2015, Volume: 29, Issue:3 Topics: Animals; Base Sequence; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Glucose; Glutamine; Immunoblotting; Insulin; Insulin Secretion; Insulin-Secreting Cells; Leucine; Malate Dehydrogenase; Mitochondria; Pyruvic Acid; Rats; RNA, Messenger; RNA, Small Interfering	2015
Metabolic abnormalities of gastrointestinal mucosa in celiac disease: An in vitro proton nuclear magnetic resonance spectroscopy study. Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:10 Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Atrophy; Biomarkers; Celiac Disease; Citric Acid Cycle; Duodenum; Female; Glycolysis; Humans; Intestinal Mucosa; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Protons; Pyruvic Acid; Succinic Acid; Young Adult	2015
Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model. American journal of physiology. Heart and circulatory physiology, 2015, Jul-01, Volume: 309, Issue:1 Topics: Acetyl-CoA Carboxylase; Amino Acids; AMP-Activated Protein Kinases; Animals; Carbon Radioisotopes; Energy Metabolism; Extracorporeal Membrane Oxygenation; Fatty Acids; Heart; Leucine; Myocardium; Oxidation-Reduction; Phosphorylation; Proton Magnetic Resonance Spectroscopy; Pyruvic Acid; Swine	2015
The Development of Leucine Dehydrogenase and Formate Dehydrogenase Bifunctional Enzyme Cascade Improves the Biosynthsis of L-tert-Leucine. Applied biochemistry and biotechnology, 2016, Volume: 180, Issue:6 Topics: Amination; Biosynthetic Pathways; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Formate Dehydrogenases; Hydrogen-Ion Concentration; Kinetics; Leucine; Leucine Dehydrogenase; Multienzyme Complexes; NAD; Oxidation-Reduction; Pyruvic Acid; Recombinant Proteins; Temperature	2016
Establishing a Mathematical Equations and Improving the Production of L-tert-Leucine by Uniform Design and Regression Analysis. Applied biochemistry and biotechnology, 2017, Volume: 181, Issue:4 Topics: Amination; Biotechnology; Escherichia coli; Formate Dehydrogenases; Genetic Engineering; Leucine; Leucine Dehydrogenase; Models, Theoretical; Pyruvic Acid; Regression Analysis; Valine	2017
Neuroprotective Effect of Creatine and Pyruvate on Enzyme Activities of Phosphoryl Transfer Network and Oxidative Stress Alterations Caused by Leucine Administration in Wistar Rats. Neurotoxicity research, 2017, Volume: 32, Issue:4 Topics: Amino Acids, Branched-Chain; Animals; Antioxidants; Cerebral Cortex; Creatine; Hippocampus; Leucine; Neuroprotective Agents; Oxidative Stress; Pyruvic Acid; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2017
The FEBS journal, 2017, Volume: 284, Issue:18 Topics: Aerobiosis; Batch Cell Culture Techniques; Butyrates; Carbon Isotopes; Citric Acid Cycle; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Magnetic Resonance Spectroscopy; Metabolome; Mitochondria; Pentose Phosphate Pathway; Pichia; Pyruvic Acid; Saccharomyces cerevisiae; Valine	2017
Understanding the high L-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics. Scientific reports, 2018, 02-26, Volume: 8, Issue:1 Topics: Alanine; Corynebacterium glutamicum; Leucine; NADP; Proteomics; Pyruvic Acid; Transcriptome; Valine	2018
Feeding the Outer Bran Fraction of Rice Alters Hepatic Carbohydrate Metabolism in Rats. Nutrients, 2020, Feb-07, Volume: 12, Issue:2 Topics: Animals; Carbohydrate Metabolism; Dietary Fiber; Dietary Supplements; Fatty Acids, Volatile; Gene Expression; Gluconeogenesis; Leucine; Liver; Male; Oryza; Pentose Phosphate Pathway; Pyruvic Acid; Rats, Sprague-Dawley; Valine	2020
Plasma Metabolomic Changes in Mice With Time-restricted Feeding-attenuated Spontaneous Metastasis of Lewis Lung Carcinoma. Anticancer research, 2020, Volume: 40, Issue:4 Topics: alpha-Tocopherol; Animals; Carcinoma, Lewis Lung; Cholestanol; Cholesterol; Diet, High-Fat; Disease Models, Animal; Docosahexaenoic Acids; Fasting; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Metabolomics; Mice; Neoplasm Metastasis; Phenylalanine; Pyruvic Acid	2020
Effect of Ketosubstrate on the Product Yield in the Transamination Reaction Catalyzed by Transaminase from Thermoproteus uzoniensis. Doklady. Biochemistry and biophysics, 2020, Volume: 490, Issue:1 Topics: Archaeal Proteins; Butyrates; Catalysis; Hydrogen-Ion Concentration; Kinetics; Leucine; Pyruvic Acid; Substrate Specificity; Temperature; Thermoproteus; Transaminases	2020
Rational modification of the carbon metabolism of Corynebacterium glutamicum to enhance L-leucine production. Journal of industrial microbiology & biotechnology, 2020, Volume: 47, Issue:6-7 Topics: Alanine; Carbon; Citric Acid Cycle; Corynebacterium glutamicum; Fermentation; Industrial Microbiology; Leucine; Metabolic Engineering; Plasmids; Pyruvic Acid; Transaminases; Valine	2020
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge. Chemosphere, 2022, Volume: 297 Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine	2022