pyruvic acid and deuterium

pyruvic acid has been researched along with deuterium in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.68)18.7374
1990's6 (19.35)18.2507
2000's12 (38.71)29.6817
2010's6 (19.35)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Kuo, DJ; Rose, IA; Warms, JV1
Anderson, VE; LaReau, RD1
Abell, LM; O'Leary, MH1
Mamer, OA1
Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN1
Biesemans, M; Malaisse, WJ; Willem, R1
Beylot, M; Diraison, F; Pachiaudi, C1
Beylot, M; Brunengraber, H; David, F; Des Rosiers, C; Previs, SF1
Gardner, KH; Kay, LE; Parris, WE; Pawson, T; Rosen, MK; Willis, RC1
Chen, X; Dieckmann, T; Jin, X; Medhekar, R; Toney, MD; Zhou, X1
Dunn, MF; Ferrari, D; Miles, EW; Yang, LH1
Ishima, R; Louis, JM; Petkova, AP; Torchia, DA1
Gilfillan, C; Gruca, L; Kalhan, SC; Parimi, P; Saker, F; Sauer, PJ; Van Beek, R1
Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP1
Blanchard, JS; Sugantino, M; Yu, M; Zheng, R1
Bisswanger, H; Liu, X1
Hedderich, R; Stojanowic, A1
Kay, LE; Tugarinov, V1
Anderson, VE; Brunengraber, H; Cendrowski, AV; David, F; Jobbins, KA; Kasumov, T1
Cerdán, S; López-Larrubia, P; Rodrigues, TB1
Bligny, R; Cornic, G; Gauthier, P; Gout, E; Hodges, M; Mahé, A; Mauve, C; Tcherkez, G1
Barb, AW; Glushka, JN; Hekmatyar, SK; Prestegard, JH1
Keshari, KR; Wilson, DM1
Bodenhausen, G; Bornet, A; Jannin, S; Melzi, R; Milani, J; Vuichoud, B1
Bandarian, V; Young, AP1
Anderson, BL; Funk, AM; Hever, T; Khemtong, C; Kovacs, Z; Malloy, CR; Sherry, AD; Wen, X1
Funk, AM; Hever, T; Khemtong, C; Malloy, CR; Maptue, NR; Sherry, AD; Wen, X1
Gamliel, A; Gomori, JM; Harris, T; Katz-Brull, R; Nardi-Schreiber, A; Sosna, J1
Kelpšas, V; Leung, A; von Wachenfeldt, C1
Barger, C; Batsios, G; Costello, JF; Gillespie, AM; Ronen, SM; Stevers, N; Taglang, C; Tran, M; Viswanath, P1
Agemy, L; Brenner, O; Frydman, L; Montrazi, ET; Peters, DC; Sasson, K; Scherz, A1

Reviews

1 review(s) available for pyruvic acid and deuterium

ArticleYear
Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization.
    Chemical Society reviews, 2014, Mar-07, Volume: 43, Issue:5

    Topics: Bioreactors; Carbon Isotopes; Deuterium; Enzymes; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvic Acid; Quantum Theory

2014

Other Studies

30 other study(ies) available for pyruvic acid and deuterium

ArticleYear
A rate-determining proton relay in the pyruvate kinase reaction.
    Biochemistry, 1991, Jan-22, Volume: 30, Issue:3

    Topics: Animals; Cobalt; Deuterium; Hydrogen; Kinetics; Magnesium; Models, Molecular; Muscles; Protons; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rabbits; Water

1991
Lactate dehydrogenase displays absolute stereospecificity in the transfer of the prochiral hydrogen of NADH.
    The Journal of biological chemistry, 1989, Sep-15, Volume: 264, Issue:26

    Topics: Animals; Deuterium; Hydrogen; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Radioisotope Dilution Technique; Stereoisomerism; Swine; Tritium

1989
Isotope effect studies of the pyruvate-dependent histidine decarboxylase from Lactobacillus 30a.
    Biochemistry, 1988, Aug-09, Volume: 27, Issue:16

    Topics: Carbon Isotopes; Carboxy-Lyases; Deuterium; Histidine Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Nitrogen Isotopes; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Schiff Bases

1988
Measurement of urinary lactic, 3-hydroxybutyric, pyruvic and acetoacetic acids in a single analysis using selected ion monitoring and stable isotope labelling techniques.
    Biomedical & environmental mass spectrometry, 1988, Jan-01, Volume: 15, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; Infant, Newborn; Isotope Labeling; Ketosis; Lactates; Pyruvates; Pyruvic Acid

1988
2-Methyl-L-tryptophan is a substrate of tryptophanase.
    Biochemistry and molecular biology international, 1995, Volume: 35, Issue:5

    Topics: Absorption; Deuterium; Escherichia coli; Indoles; Ions; Kinetics; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Serine; Substrate Specificity; Tryptophan; Tryptophanase

1995
Generation of C3- and C2-deuterated L-lactic acid by human erythrocytes exposed to D-[1-13C]glucose, D-[2-13C]glucose and D-[6-13C]glucose in the presence of D2O.
    The International journal of biochemistry, 1994, Volume: 26, Issue:5

    Topics: Alanine; Alanine Transaminase; Carbon Isotopes; Deuterium; Erythrocytes; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid

1994
In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Acetyl Coenzyme A; Animals; Blood Chemical Analysis; Blood Glucose; Cholesterol; Deuterium; Deuterium Oxide; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lactates; Lactic Acid; Liver; Male; Palmitates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Triglycerides

1996
Assay of the 13C and 2H mass isotopomer distribution of phosphoenolpyruvate by gas chromatography/mass spectrometry.
    Journal of mass spectrometry : JMS, 1996, Volume: 31, Issue:6

    Topics: Animals; Borohydrides; Carbon Isotopes; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicators and Reagents; Lactic Acid; Oxidation-Reduction; Perfusion; Peroxides; Phosphoenolpyruvate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide

1996
Selective methyl group protonation of perdeuterated proteins.
    Journal of molecular biology, 1996, Nov-15, Volume: 263, Issue:5

    Topics: Amino Acids; Bacteria; Deuterium; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Proteins; Protons; Pyruvic Acid

1996
Rapid kinetic and isotopic studies on dialkylglycine decarboxylase.
    Biochemistry, 2001, Feb-06, Volume: 40, Issue:5

    Topics: Alanine; Aminoisobutyric Acids; Carbon Isotopes; Carboxy-Lyases; Decarboxylation; Deuterium; Enzyme Activation; Isoenzymes; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyridoxal Phosphate; Pyruvic Acid; Transaminases

2001
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
    Biochemistry, 2001, Jun-26, Volume: 40, Issue:25

    Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase

2001
Comparison of methyl rotation axis order parameters derived from model-free analyses of (2)H and (13)C longitudinal and transverse relaxation rates measured in the same protein sample.
    Journal of the American Chemical Society, 2001, Jun-27, Volume: 123, Issue:25

    Topics: Amino Acids; Carbon Isotopes; Deuterium; Deuterium Oxide; HIV Protease; Models, Theoretical; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Pyruvic Acid; Recombinant Proteins

2001
Estimation of gluconeogenesis in newborn infants.
    American journal of physiology. Endocrinology and metabolism, 2001, Volume: 281, Issue:5

    Topics: Amino Acids; Blood Glucose; Body Water; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Gluconeogenesis; Glucose; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Lactic Acid; Parenteral Nutrition; Pregnancy; Pregnancy in Diabetics; Pyruvic Acid

2001
Amino acid kinetics during the anhepatic phase of liver transplantation.
    Diabetes, 2002, Volume: 51, Issue:6

    Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid

2002
Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids.
    Biochemistry, 2003, Jan-14, Volume: 42, Issue:1

    Topics: Amino Acids; Bacterial Proteins; Catalysis; Deuterium; Enzyme Activation; Hemiterpenes; Hydrogen-Ion Concentration; Hydroxymethyl and Formyl Transferases; Keto Acids; Metals; Molecular Conformation; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Pantothenic Acid; Protons; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tetrahydrofolates

2003
Solvent isotope effect on the reaction catalysed by the pyruvate dehydrogenase complex from Escherichia coli.
    Biological chemistry, 2003, Volume: 384, Issue:4

    Topics: Coenzymes; Deuterium; Deuterium Oxide; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Protons; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Radioisotopes; Solvents; Temperature

2003
CO2 reduction to the level of formylmethanofuran in Methanosarcina barkeri is non-energy driven when CO is the electron donor.
    FEMS microbiology letters, 2004, Jun-01, Volume: 235, Issue:1

    Topics: Carbon Dioxide; Carbon Monoxide; Cell Membrane; Deuterium; Electrons; Energy Metabolism; Furans; Methane; Methanosarcina barkeri; Mutation; Oxidation-Reduction; Oxidoreductases; Pyruvic Acid

2004
Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface.
    Biochemistry, 2005, Dec-13, Volume: 44, Issue:49

    Topics: Acetyl Coenzyme A; Binding Sites; Carbon Isotopes; Deuterium; Isoenzymes; Isoleucine; Leucine; Malate Synthase; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyruvic Acid; Valine

2005
Mass isotopomer study of anaplerosis from propionate in the perfused rat heart.
    Archives of biochemistry and biophysics, 2007, Jul-01, Volume: 463, Issue:1

    Topics: Acyl Coenzyme A; Animals; Carbon Isotopes; Citric Acid Cycle; Deuterium; Glucose; In Vitro Techniques; Lactic Acid; Male; Myocardium; Perfusion; Propionates; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2007
Redox dependence and compartmentation of [13C]pyruvate in the brain of deuterated rats bearing implanted C6 gliomas.
    Journal of neurochemistry, 2009, Volume: 109 Suppl 1

    Topics: Animals; Astrocytes; Brain Chemistry; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Cerebral Cortex; Deuterium; Glioma; Glucose; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methylation; Neoplasm Transplantation; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar

2009
In folio respiratory fluxomics revealed by 13C isotopic labeling and H/D isotope effects highlight the noncyclic nature of the tricarboxylic acid "cycle" in illuminated leaves.
    Plant physiology, 2009, Volume: 151, Issue:2

    Topics: Carbon Dioxide; Carbon Isotopes; Cell Respiration; Citric Acid Cycle; Decarboxylation; Deuterium; Fumarates; Glucose; Isotope Labeling; Light; Photosynthesis; Plant Leaves; Plant Transpiration; Pyruvic Acid; Succinic Acid; Xanthium

2009
Probing alanine transaminase catalysis with hyperpolarized 13CD3-pyruvate.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2013, Volume: 228

    Topics: Alanine Transaminase; Carbon Isotopes; Catalysis; Deuterium; Nuclear Magnetic Resonance, Biomolecular; Protons; Pyruvic Acid; Sensitivity and Specificity; Signal Processing, Computer-Assisted

2013
Hyperpolarization of deuterated metabolites via remote cross-polarization and dissolution dynamic nuclear polarization.
    The journal of physical chemistry. B, 2014, Feb-06, Volume: 118, Issue:5

    Topics: Deuterium; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid; Temperature

2014
Mechanistic Studies of the Radical S-Adenosyl-L-methionine Enzyme 4-Demethylwyosine Synthase Reveal the Site of Hydrogen Atom Abstraction.
    Biochemistry, 2015, Jun-16, Volume: 54, Issue:23

    Topics: Archaeal Proteins; Biocatalysis; Carbon Radioisotopes; Carboxy-Lyases; Catalytic Domain; Deuterium; Free Radicals; Guanosine; Iron-Sulfur Proteins; Methanococcus; Methylation; Models, Molecular; Pyruvic Acid; RNA, Archaeal; RNA, Transfer, Phe; S-Adenosylmethionine; Stereoisomerism

2015
The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2017, Volume: 284

    Topics: Animals; Citric Acid Cycle; Deuterium; Fructose-Bisphosphate Aldolase; Glucose; Glycolysis; Isotope Labeling; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2017
Effects of deuteration on transamination and oxidation of hyperpolarized
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2019, Volume: 301

    Topics: Alanine; Alanine Transaminase; Amination; Animals; Carbon Isotopes; Deuterium; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Water

2019
The Effect of Gadolinium Doping in [
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2020, 02-04, Volume: 21, Issue:3

    Topics: Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Deuterium; Gadolinium; Glucose; Pyruvic Acid

2020
Evolving
    International journal of molecular sciences, 2021, Sep-07, Volume: 22, Issue:18

    Topics: Adaptation, Physiological; Culture Media; Deuterium; Escherichia coli; Gene Expression Regulation, Bacterial; Isotope Labeling; Magnetic Resonance Spectroscopy; Mutation; Pyruvic Acid; Recombinant Proteins; Sodium

2021
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 08-15, Volume: 28, Issue:16

    Topics: Animals; Deuterium; Glioblastoma; Lactic Acid; Mice; NAD; Pyruvic Acid; Telomerase

2022
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models.
    Scientific reports, 2023, Nov-15, Volume: 13, Issue:1

    Topics: Acute Disease; Animals; Deuterium; Disease Models, Animal; Humans; Lactic Acid; Magnetic Resonance Imaging; Mice; Pancreatic Neoplasms; Pancreatitis; Pyruvic Acid

2023