pyruvic acid and cyclosporine

pyruvic acid has been researched along with cyclosporine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (50.00)18.2507
2000's4 (33.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buckels, J; Cramb, R; Dousset, B; Krentz, AJ; Mayer, D; McMaster, P; Nattrass, M; Smith, JM1
Brooks, GA; Hokanson, JF; Mercier, JG1
Herman, B; Imberti, R; Lemasters, JJ; Nieminen, AL1
Conde, M; MontaƱo, R; Moreno-Aurioles, VR; Ramirez, R; Sanchez-Madrid, F; Sanchez-Mateos, P; Sobrino, F1
Carlile, GW; Chalmers-Redman, RM; Fraser, AD; Pong, A; Tatton, WG1
Brambilla, L; Cantoni, O; Sestili, P1
Bachurin, SO; Kireeva, EG; Shevtzova, EF1
Bullock, R; Gilman, C; Kunene, N; Mazzeo, A; Samuelson, R; Young, HF1
Alves, OL; Gilman, CB; Hayes, RL; Mazzeo, AT; Niki Kunene, K; Ross Bullock, M; Tolias, C1
Norenberg, MD; Rama Rao, KV; Reddy, PV1
Amaral, AU; Castilho, RF; Cecatto, C; Wajner, M1
Geshi, M; Matoba, S; Nagai, T; Parnpai, R; Somfai, T; Suttirojpattana, T1

Trials

2 trial(s) available for pyruvic acid and cyclosporine

ArticleYear
Metabolic effects of cyclosporin A and FK 506 in liver transplant recipients.
    Diabetes, 1993, Volume: 42, Issue:12

    Topics: Analysis of Variance; Azathioprine; Blood Glucose; Body Mass Index; C-Peptide; Cyclosporine; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Liver Transplantation; Male; Middle Aged; Prospective Studies; Pyruvates; Pyruvic Acid; Reference Values; Tacrolimus

1993
Brain metabolic and hemodynamic effects of cyclosporin A after human severe traumatic brain injury: a microdialysis study.
    Acta neurochirurgica, 2008, Volume: 150, Issue:10

    Topics: Adult; Brain; Brain Injuries; Cerebrovascular Circulation; Cyclosporine; Double-Blind Method; Energy Metabolism; Extracellular Fluid; Female; Glucose; Humans; Male; Microdialysis; Middle Aged; Mitochondria; Neuroprotective Agents; Placebos; Pyruvic Acid; Treatment Outcome; Young Adult

2008

Other Studies

10 other study(ies) available for pyruvic acid and cyclosporine

ArticleYear
Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats.
    American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:5

    Topics: Adenosine Diphosphate; Animals; Cyclosporine; Female; In Vitro Techniques; Malates; Mitochondria, Muscle; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinates; Succinic Acid

1995
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fructose; Glycolysis; Intracellular Membranes; Lactates; Lactic Acid; Liver; Male; Membrane Potentials; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Peroxides; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Trifluoperazine

1993
Anti-CD69 antibodies enhance phorbol-dependent glucose metabolism and Ca2+ levels in human thymocytes. Antagonist effect of cyclosporin A.
    Journal of leukocyte biology, 1996, Volume: 60, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cyclosporine; Diglycerides; Drug Interactions; Fructosediphosphates; Glucose; Glycolysis; Humans; Immunosuppressive Agents; Lactates; Lactic Acid; Lectins, C-Type; Pyruvates; Pyruvic Acid; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymus Gland; Tritium

1996
Glucose protection from MPP+-induced apoptosis depends on mitochondrial membrane potential and ATP synthase.
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Atractyloside; Cell Nucleus; Cell Survival; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Drug; Glucose; Glycolysis; Membrane Potentials; Microscopy, Confocal; Mitochondria; Nerve Growth Factors; Oligomycins; PC12 Cells; Proton-Translocating ATPases; Pyruvic Acid; Rats; Time Factors

1999
Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate.
    FEBS letters, 1999, Aug-20, Volume: 457, Issue:1

    Topics: Apoptosis; Cell Count; Cell Division; Cell Survival; Cyclosporine; DNA Fragmentation; Enzyme Inhibitors; Humans; Kinetics; Necrosis; Pyruvic Acid; Rotenone; tert-Butylhydroperoxide; Time Factors; U937 Cells; Uncoupling Agents

1999
Effect of beta-amyloid peptide fragment 25-35 on nonselective permeability of mitochondria.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:6

    Topics: Amyloid beta-Peptides; Animals; Brain; Calcium; Cyclosporine; Cytochrome c Group; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Intracellular Membranes; Lactates; Lipid Peroxidation; Liver; Mitochondria; Neurons; Norepinephrine; Peptide Fragments; Pyruvic Acid; Rats; Rats, Wistar; Time Factors

2001
Synthes Award For Resident Research On Craniofacial And Brain Injury: effect of cyclosporin A, topiramate, or 100% oxygen as proposed "neuroprotective" therapies on the neurochemical analytes in patients with severe traumatic brain injury.
    Clinical neurosurgery, 2006, Volume: 53

    Topics: Adult; Awards and Prizes; Brain Injuries; Case-Control Studies; Cohort Studies; Cyclosporine; Fructose; Glucose; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Neuroprotective Agents; Oxygen Inhalation Therapy; Pyruvic Acid; Topiramate

2006
Inhibitors of the mitochondrial permeability transition reduce ammonia-induced cell swelling in cultured astrocytes.
    Journal of neuroscience research, 2009, Volume: 87, Issue:12

    Topics: Ammonia; Animals; Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Cell Size; Cells, Cultured; Cyclosporine; Hepatic Encephalopathy; Hyperammonemia; Magnesium; Minocycline; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pyruvic Acid; Rats; Trifluoperazine; Water-Electrolyte Balance

2009
2-Methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria.
    Journal of neurochemistry, 2016, Volume: 137, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Brain; Calcium; Citrates; Cyclosporine; Energy Metabolism; Glutamate Dehydrogenase; Glutamic Acid; Humans; Ketoglutaric Acids; Malates; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Phosphorylation; Oxygen Consumption; Propionic Acidemia; Pyruvic Acid; Rats; Rats, Wistar

2016
Effect of medium additives during liquid storage on developmental competence of in vitro matured bovine oocytes.
    Animal science journal = Nihon chikusan Gakkaiho, 2017, Volume: 88, Issue:2

    Topics: Animals; Cattle; Cells, Cultured; Culture Media; Cyclosporine; Dithiothreitol; Embryonic Development; Female; Fertilization in Vitro; HEPES; In Vitro Techniques; Oocytes; Pyruvic Acid; Serum; Tissue Preservation

2017