pyruvic acid has been researched along with aspartic acid in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (29.20) | 18.7374 |
| 1990's | 19 (16.81) | 18.2507 |
| 2000's | 26 (23.01) | 29.6817 |
| 2010's | 30 (26.55) | 24.3611 |
| 2020's | 5 (4.42) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Berry, MN; Gregory, RB; Phillips, JW | 1 |
| Greene, LW; Wu, G | 1 |
| Altekar, W; Rajagopalan, R | 1 |
| Field, CJ; Marliss, EB; Wu, GY | 1 |
| Dumdey, R; Holzhütter, HG; Müller, M; Rathmann, J | 1 |
| Matsuno, T | 2 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Bielarczyk, H; Lysiak, W; Szutowicz, A | 1 |
| Durbin, RD; Langston-Unkefer, PJ; London, RE; Uchytil, TF; Unkefer, CJ | 1 |
| Lenartowicz, E; Wojtczak, AB | 1 |
| Iwashima, A; Nagasaki, H; Wakabayashi, Y; Yamada, R | 1 |
| Thompson, JR; Wu, GY | 1 |
| Bryan, BM; Fiskum, G; Holleran, AL; Kelleher, JK; Mallet, RT; Murphy, AN | 1 |
| Cooper, AJ; Fitzpatrick, SM; Hertz, L | 1 |
| Burnell, JN; Hatch, MD | 1 |
| Cheeseman, AJ; Clark, JB | 1 |
| Akuffo, V; Costello, LC; Franklin, RB | 1 |
| Ayuso, MS; Bengoa, B; Martín-Requero, A; Parrilla, R; Pérez-Sala, D | 1 |
| Gordon, S; Newsholme, EA; Newsholme, P | 1 |
| Miyamae, Y; Ohta, T; Sugano, T; Tarui, A | 1 |
| Davis, EJ; Scaduto, RC | 1 |
| Ozand, PT; Sumbilla, CM; Zielke, HR | 1 |
| Coleman, PS; Lavietes, BB | 1 |
| Hassinen, IE; Hiltunen, JK; Nuutinen, EM; Peuhkurinen, KJ; Pietiläinen, EP | 1 |
| Ivanov, VE; Pisarenko, OI; Solomatina, ES; Studneva, IM | 1 |
| Best, L; Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Casanello-Ertl, D; Duducgian-Vartavarian, L; Pardridge, WM | 1 |
| Bleese, N; Döring, V; Rodewald, G | 1 |
| Baal, MG; Gabreëls, FJ; Gijsbers, TH; Hommes, FA; Kok, JC; Lamers, KJ; Renier, WO | 1 |
| Deaciuc, IV; Ilonca, A | 1 |
| Catelloni, F; Fontaine, E; Keriel, C; Leverve, XM; Rigoulet, M; Sibille, B | 1 |
| Canioni, P; Merle, M; Portais, JC; Schuster, R | 1 |
| Butwell, NB; Malloy, CR; Sherry, AD; Sumegi, B | 1 |
| Scaduto, RC | 1 |
| Huang, X; McKenna, MC; Sonnewald, U; Stevenson, J; Zielke, HR | 1 |
| Barak, C; Jessen, ME; Malloy, CR; Maniscalco, SP; Reed, MK | 1 |
| Dabrosin, C; Hallström, A; Hammar, M; Ungerstedt, U | 1 |
| Andersson, K; Chen, Y; Dell'Anna, E; Engidawork, E; Goiny, M; Herrera-Marschitz, M; Lubec, G; Ungerstedt, U | 1 |
| Aasly, J; Bakken, IJ; Sonnewald, U; Unsgård, G; White, LR | 1 |
| Follette, DM; Segel, LD | 1 |
| Chun, YS; Kim, MS; Kwak, SJ; Park, JW; Park, SC; Park, YC | 1 |
| Aasly, J; Bakken, IJ; Håberg, A; Haraldseth, O; Qu, H; Sande, LM; Sonnewald, U; Unsgård, G; White, LR | 1 |
| Backlund, P; Cooper, GW; de la Haba, G; Flaks, JG; Khatami, M | 1 |
| Fotheringham, IG; Grinter, N; Pantaleone, DP; Senkpeil, RF; Taylor, PP | 1 |
| Chang, AK; Duggleby, RG; Li, W; Nixon, PF; Wu, YG | 1 |
| Decking, UK; Deussen, A; Preckel, B; Schrader, J; Skwirba, S; Thämer, V; Zimmermann, MF | 1 |
| Jordan, F; Sergienko, EA | 1 |
| Dunn, MF; Ferrari, D; Miles, EW; Yang, LH | 1 |
| Andersson, K; Chen, Y; Dell'Anna, E; Engidawork, E; Goiny, M; Gross, J; Herrera-Marschitz, M; Kohlhauser, C; Loidl, F; Lubec, B; Lubec, G; Stoeckler, S | 1 |
| Qu, H; Schousboe, A; Sonnewald, U; Waagepetersen, HS | 1 |
| Bryła, J; Derlacz, RA; Jagielski, AK; Jarzyna, R; Lietz, T; Winiarska, K; Wohner, D | 1 |
| Dobson, RC; Gerrard, JA; Morris, JC; Roberts, SJ | 1 |
| Bracht, A; Bracht, L; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Lousano, SH; Yassuda Filho, P | 1 |
| Anstrom, DM; Kallio, K; Remington, SJ | 1 |
| CHELDELIN, VH; CHRISTENSEN, BE; THOMAS, RC; WANG, CH | 1 |
| ROSENGARTEN, H | 1 |
| GEIGER, A; GOMBOS, G; OTSUKI, S | 1 |
| KRAHL, ME; WOLL, IG | 1 |
| BALAZS, R | 1 |
| DAVIS-VANTHIENEN, W; SLATER, EC; TAMBLYN-HAGUE, C | 1 |
| AWAPARA, J; SIMPSON, JW | 1 |
| Bertoldi, M; Borri Voltattorni, C; Cellini, B | 1 |
| Carvalho, RA; Jeffrey, FM; Malloy, CR; Rodrigues, TB; Sherry, AD; Zhao, P | 1 |
| Islam, MN; Kondo, H; Sueda, S; Yong-Biao, J | 1 |
| Chaudhary, LC; McKain, N; Miyagawa, E; Walker, ND; Wallace, RJ | 1 |
| Dobson, RC; Gerrard, JA; Healy, JP; Hutton, CA; Turner, JJ | 1 |
| Bryla, J; Chodnicka, K; Doroszewska, R; Drozak, J; Winiarska, K | 1 |
| Hertz, L; Kala, G | 1 |
| Eggeling, L; Kennerknecht, N; Marienhagen, J; Sahm, H | 1 |
| Locas, CP; O'Brien, J; Wnorowski, A; Yaylayan, VA | 1 |
| Horiuchi, M; Iijima, M; Kannan, Y; Kobayashi, K; Li, MX; Moriyama, M; Nakamura, Y; Saheki, T; Sinasac, DS; Tanaka, M; Tsui, LC | 1 |
| Almeida, J; Ataíde, A; Borges, L; Correia, C; Coutinho, AM; Diogo, L; Grazina, M; Marques, C; Miguel, T; Oliveira, C; Oliveira, G; Vicente, AM | 1 |
| Le Bars, D; Yvon, M | 1 |
| Cabrières, MC; Franssen, MC; Levisson, M; van der Oost, J; Wolterink-van Loo, S | 1 |
| Bresolin, N; Brighina, E; Pardi, G; Rango, M | 1 |
| Cameron, JM; Des Rosiers, C; Khairallah, M; Pencharz, PB; Riazi, R; Robinson, BH | 1 |
| Eisenreich, W; Eylert, E; Fuchs, TM; Goebel, W; Joseph, B; Loeffler, DI; Schär, J; Schauer, K; Stoll, R | 1 |
| Agashe, H; Awasthi, V; Doblas, S; Towner, R | 1 |
| Bala Amutha, K; Murugesan, AG | 1 |
| de Villiers, J; Koekemoer, L; Strauss, E | 1 |
| Cerdan, S; Contreras, L; Garzón, M; Kobayashi, K; Llorente-Folch, I; Pardo, B; Rodrigues, TB; Saheki, T; Satrústegui, J | 1 |
| Baverel, G; El Hage, M; Ferrier, B; Martin, G | 1 |
| Bouchard, B; Isern, N; Ning, XH; Olson, AK; Portman, MA; Rosiers, CD | 1 |
| Gaynutdinov, T; Gellerich, FN; Gizatullina, Z; Heinze, HJ; Korzeniewski, B; Seppet, E; Striggow, F; Trumbekaite, S; Vielhaber, S | 1 |
| Kachroo, AH; Kalyani, JN; Mahadevan, S; Ramachandra, N; Savithri, HS | 1 |
| Han, W; Lee, P; Leong, W; Lim, M; Radda, GK; Tan, T | 1 |
| Hertz, L; Li, B; Peng, L | 1 |
| Gainutdinov, T; Gellerich, FN; Gizatullina, Z; Muth, K; Orynbayeva, Z; Seppet, E; Vielhaber, S | 1 |
| Chertov, AO; Cleghorn, WM; Contreras, L; Du, J; Hurley, JB; Lindsay, K; Linton, J; Paquet-Durand, F; Rountree, AM; Sadilek, M; Sahaboglu, A; Satrústegui, J; Sweet, IR; Turner, SJ | 1 |
| Bozsó, Z; Fülöp, L; Juhász, G; Penke, B; Szegedi, V; Varga, E | 1 |
| Das, P; Dwivedi, SN; Gupta, SD; Jagannathan, NR; Makharia, GK; Mewar, S; Mishra, A; Sharma, U; Upadhyay, D | 1 |
| Adina-Zada, A; Attwood, PV; Choosangtong, K; Jitrapakdee, S; Sirithanakorn, C; Wallace, JC | 1 |
| Abu-Remaileh, M; Birsoy, K; Chen, WW; Freinkman, E; Sabatini, DM; Wang, T | 1 |
| Bush, LN; Freinkman, E; Gui, DY; Hosios, AM; Sullivan, LB; Vander Heiden, MG | 1 |
| Blyth, K; Bulusu, V; Cardaci, S; Fleming, S; Gottlieb, E; Kalna, G; Kamphorst, JJ; MacKay, G; MacKenzie, ED; Nixon, C; Schiavi, F; Stevenson, D; Strathdee, D; Tumanov, S; van den Broek, NJ; Vazquez, A; Zheng, L | 1 |
| Al-Haideri, H; Kelly, DJ; White, MA | 1 |
| Castro-Vega, LJ; Favier, J; Gimenez-Roqueplo, AP; Hollinshead, KE; Janin, M; Ludwig, C; Lussey-Lepoutre, C; Martinelli, C; Menara, M; Metallo, C; Morin, A; Ottolenghi, C; Parker, SJ; Tennant, DA | 1 |
| Chaudhary, S; Dewangan, RP; Gopal, B; Kumar, A; Navratna, V; Pramanik, A; Ramachandran, S; Rayasam, G; Shrivastava, P; Silla, Y | 1 |
| Alper, HS; Cordova, LT | 1 |
| Bush, LN; Davidson, SM; Freinkman, E; Gitego, N; Gui, DY; Hosios, AM; Luengo, A; Sullivan, LB; Thomas, CJ; Vander Heiden, MG | 1 |
| Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K | 1 |
| Krishnamurthy, R; Nelson, J; Rhea, CJ; Springsteen, G; Yerabolu, JR | 1 |
| He, Q; Huang, F; Li, J; Shao, Y; Wang, T; Yao, W | 1 |
| Beyrath, J; Iannetti, EF; Koopman, WJH; Smeitink, JAM; Willems, PHGM | 1 |
| Eto, K; Funahashi, A; Furuie, S; Furukawa, T; Gao, Q; Horiuchi, M; Kadowaki, T; Kuroda, E; Moriyama, M; Nakamura, Y; Saheki, T; Setogawa, Y; Sinasac, DS; Tai, YH; Takano, K; Ushikai, M; Yamamura, KI; Yasuda, I | 1 |
| Contreras, L; Del Arco, A; Pardo, B; Puertas-Frías, G; Satrústegui, J | 1 |
| Bamberger, A; Debska-Vielhaber, G; Doenst, T; Endres, T; Gainutdinov, T; Gellerich, FN; Gizatullina, Z; Hallmann, K; Heinze, HJ; Karavasili, N; Kunz, M; Kunz, WS; Lessmann, V; Schreiber, F; Schwarzer, M; Szibor, M; Vielhaber, S | 1 |
| Kerkhofs, M | 1 |
| Bloch, J; Comment, A; Cudalbu, C; Gruetter, R; Gusyatiner, O; Hamou, MF; Hegi, ME; Lanz, B; Mishkovsky, M; Vassallo, I | 1 |
| Holeček, M | 1 |
| Calmettes, G; John, S; Ribalet, B; Xu, S | 1 |
6 review(s) available for pyruvic acid and aspartic acid
| Article | Year |
|---|---|
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Fetus; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid | 2009 |
The control of brain mitochondrial energization by cytosolic calcium: the mitochondrial gas pedal.
Topics: Adenosine Diphosphate; Amino Acid Transport Systems, Acidic; Antiporters; Aspartic Acid; Calcium; Circadian Rhythm; Cytosol; Energy Metabolism; Feedback, Physiological; Humans; Intracellular Membranes; Malates; Mitochondria; Mitochondrial Membrane Transport Proteins; Neurons; Oxidative Phosphorylation; Pyruvic Acid; Suprachiasmatic Nucleus | 2013 |
Central metabolic nodes for diverse biochemical production.
Topics: Acetyl Coenzyme A; Aspartic Acid; Bacteria; Citric Acid; Fungi; Pyruvic Acid; Tyrosine | 2016 |
Cytosolic Ca
Topics: Animals; Aspartic Acid; Calcium; Cytosol; Humans; Malates; Mitochondria; Pyruvic Acid | 2020 |
Roles of malate and aspartate in gluconeogenesis in various physiological and pathological states.
Topics: Aspartic Acid; Gluconeogenesis; Glutamates; Lactic Acid; Malates; Pyruvic Acid | 2023 |
107 other study(ies) available for pyruvic acid and aspartic acid
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis; Glutamates; Glutamic Acid; Hydrogen; Hyperthyroidism; Hypothyroidism; Male; Malonates; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Thyroid Gland; Urea | 1992 |
Glutamine and glucose metabolism in bovine blood lymphocytes.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Blood Glucose; Cattle; Glutamates; Glutamic Acid; Glutamine; Humans; In Vitro Techniques; Lactates; Lactic Acid; Lymphocytes; Male; Pyruvates; Pyruvic Acid; Rats | 1992 |
Products of non-reductive CO2 assimilation in the halophilic archaebacterium Haloferax mediterranei.
Topics: Alanine; Amino Acids; Ammonia; Archaea; Aspartic Acid; Bicarbonates; Carbon Dioxide; Glutamates; Glutamic Acid; Keto Acids; Propionates; Pyruvates; Pyruvic Acid; Sodium; Sodium Bicarbonate | 1991 |
Glucose and glutamine metabolism in rat macrophages: enhanced glycolysis and unaltered glutaminolysis in spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Female; Glucose; Glutamates; Glutamine; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Macrophages; Pentose Phosphate Pathway; Peritoneal Cavity; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB | 1991 |
Pyruvate utilization of rabbit reticulocytes--a compartmental study.
Topics: Alanine; Animals; Aspartic Acid; Cell Compartmentation; Citric Acid Cycle; Decarboxylation; Glutamine; Kinetics; Mitochondria; Pyruvates; Pyruvic Acid; Rabbits; Reticulocytes | 1990 |
End products of glutamine oxidation in MC-29 virus-induced chicken hepatoma mitochondria.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Citric Acid Cycle; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Synthesis of glutamate and aspartate in rat brain synaptosomes.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Brain; Citrates; Citric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
The biosynthesis of tabtoxinine-beta-lactam. Use of specifically 13C-labeled glucose and 13C NMR spectroscopy to identify its biosynthetic precursors.
Topics: Aspartic Acid; Azetidines; Azetines; Glucose; Glutamate-Ammonia Ligase; Lysine; Magnetic Resonance Spectroscopy; Mathematics; Protein Precursors; Pseudomonas; Pyruvates; Pyruvic Acid | 1987 |
Significance of the alanine aminotransferase reaction in the formation of alpha-ketoglutarate in rat liver mitochondria.
Topics: Alanine; Alanine Transaminase; Animals; Aspartic Acid; Citrates; Citric Acid; Glutamates; Glutamic Acid; Ketoglutaric Acids; Malates; Male; Mitochondria, Liver; Oxaloacetates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Presence of D-aspartate oxidase in rat liver and mouse tissues.
Topics: Amino Acid Oxidoreductases; Animals; Aspartic Acid; D-Aspartate Oxidase; Flavin-Adenine Dinucleotide; Glutamates; Glutamic Acid; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; Oxaloacetates; Oxygen; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Aspartic Acid; Chickens; Fasting; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Intracellular Fluid; Ketone Bodies; Muscles; Pyruvates; Pyruvic Acid | 1988 |
Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios.
Topics: Animals; Aspartic Acid; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Ion Exchange; Citric Acid Cycle; Liver Neoplasms, Experimental; Pyruvates; Pyruvic Acid; Rats | 1987 |
Effects of ammonia and beta-methylene-DL-aspartate on the oxidation of glucose and pyruvate by neurons and astrocytes in primary culture.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Aspartate Aminotransferases; Aspartic Acid; Astrocytes; Brain; Carbon Dioxide; Cells, Cultured; Energy Metabolism; Glucose; Mice; Neurons; Oxidation-Reduction; Phosphocreatine; Pyruvates; Pyruvic Acid | 1988 |
Photosynthesis in phosphoenolpyruvate carboxykinase-type C4 plants: pathways of C4 acid decarboxylation in bundle sheath cells of Urochloa panicoides.
Topics: Aspartic Acid; Chloroplasts; Decarboxylation; Kinetics; Light; Malates; Oxaloacetates; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Photosynthesis; Picolinic Acids; Poaceae; Pyruvates; Pyruvic Acid | 1988 |
Influence of the malate-aspartate shuttle on oxidative metabolism in synaptosomes.
Topics: Acetylcholine; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Cytosol; Energy Metabolism; Glucose; Lactates; Lactic Acid; Malates; Male; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Net citrate production by isolated prostate epithelial cells.
Topics: Acetyl Coenzyme A; Animals; Aspartate Aminotransferases; Aspartic Acid; Citrates; Citric Acid; Epithelium; Glutamate Dehydrogenase; Ketoglutaric Acids; Male; Mitochondria; Oxaloacetates; Prostate; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Rate-limiting steps for protein synthesis in isolated rat liver cells. Role of aspartate availability.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Aspartic Acid; Cell Separation; Cycloserine; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Fatty Acids; Female; Glucose; Glutamine; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Macrophages; Mice; Mice, Inbred C57BL; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1987 |
Effects of alanine on malate-aspartate shuttle in perfused livers from cold-exposed rats.
Topics: Adrenalectomy; Alanine; Alanine Transaminase; Aminooxyacetic Acid; Animals; Asparagine; Aspartic Acid; Cold Temperature; Dexamethasone; Ethanol; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol | 1986 |
The involvement of pyruvate cycling in the metabolism of aspartate and glycerate by the perfused rat kidney.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Cytosol; Gluconeogenesis; Glyceric Acids; In Vitro Techniques; Kidney; Malate Dehydrogenase; Male; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Effect of glucose on aspartate and glutamate synthesis by human diploid fibroblasts.
Topics: Aspartic Acid; Cell Line; Fibroblasts; Glucose; Glutamates; Glutamic Acid; Humans; Pyruvates; Pyruvic Acid | 1981 |
Role of pyruvate carboxylation in the energy-linked regulation of pool sizes of tricarboxylic acid-cycle intermediates in the myocardium.
Topics: Alanine; Animals; Aspartic Acid; Bicarbonates; Citrates; Citric Acid; Citric Acid Cycle; Female; Glutamates; Glutamic Acid; Heart Arrest; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Malates; Mitochondria, Heart; Myocardium; Potassium Chloride; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
[Effect of glutamic acid on the anaerobic formation of ATP in the heart muscle].
Topics: Adenosine Triphosphate; Anaerobiosis; Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lactates; Myocardium; Pyruvates; Pyruvic Acid; Rats | 1984 |
The stimulus-secretion coupling of amino acid-induced insulin release: metabolism of L-asparagine in pancreatic islets.
Topics: Acetyl Coenzyme A; Animals; Asparaginase; Asparagine; Aspartic Acid; Cytosol; Fatty Acids; Islets of Langerhans; Kinetics; Mitochondria; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1984 |
Effects of dichloroacetate on the lactate/pyruvate ratio and on aspartate and leucine metabolism in cultured rat skeletal muscle cells.
Topics: Acetates; Animals; Aspartic Acid; Carbon Dioxide; Cells, Cultured; Culture Media; Dichloroacetic Acid; Lactates; Lactic Acid; Leucine; Male; Muscles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Multi dose cardioplegic perfusion: a tool for long term heart arrest.
Topics: Aortic Valve; Aspartic Acid; Extracorporeal Circulation; Glucose; Heart Arrest, Induced; Heart Valve Diseases; Heart Valve Prosthesis; Hematocrit; Humans; Hydroxybutyrates; Mitral Valve; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Solutions; Sorbitol | 1984 |
A patient with pyruvate carboxylase deficiency in the liver: treatment with aspartic acid and thiamine.
Topics: Aspartic Acid; Child; Female; Humans; Lactates; Lactic Acid; Liver; Psychological Tests; Pyruvate Carboxylase Deficiency Disease; Pyruvates; Pyruvic Acid; Thiamine | 1981 |
Effect of adenosine on gluconeogenesis in the perfused liver of chicken and guinea-pig.
Topics: Adenosine; Animals; Aspartic Acid; Chickens; Female; Gluconeogenesis; Guinea Pigs; Humans; Lactates; Lactic Acid; Liver; Malates; Perfusion; Pyruvates; Pyruvic Acid | 1981 |
Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes.
Topics: 2,4-Dinitrophenol; Adenine Nucleotides; Animals; Aspartic Acid; Caprylates; Cell Separation; Dihydroxyacetone; Dinitrophenols; Electron Transport; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon [1-13C]glucose incubation.
Topics: Alanine; Aspartic Acid; Carbon Isotopes; Citric Acid Cycle; Glioma; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glycogen; Glycolysis; Kinetics; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mathematics; Models, Biological; Pentose Phosphate Pathway; Perchlorates; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1993 |
Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
Topics: Acetates; Acetylation; Animals; Aspartic Acid; Binding, Competitive; Carbon Isotopes; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid | 1994 |
Calcium and 2-oxoglutarate-mediated control of aspartate formation by rat heart mitochondria.
Topics: Animals; Aspartic Acid; Calcium; Dinitrophenols; Enzyme Activation; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Malates; Membrane Potentials; Mitochondria, Heart; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats | 1994 |
Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Biological Transport; Cell Compartmentation; Cells, Cultured; Citric Acid Cycle; Culture Media, Conditioned; Extracellular Space; Glutamic Acid; Glutamine; Lactates; Magnetic Resonance Spectroscopy; Mice; Pyruvates; Pyruvic Acid; Rats | 1996 |
Effects of glutamate and aspartate on myocardial substrate oxidation during potassium arrest.
Topics: Acetoacetates; Animals; Aspartic Acid; Carbon Radioisotopes; Citric Acid Cycle; Fatty Acids; Glucose; Glutamic Acid; Heart; Heart Arrest, Induced; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Oxygen Consumption; Potassium; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Effect of perinatal asphyxia on systemic and intracerebral pH and glycolysis metabolism in the rat.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Chemistry; Brain Diseases; Corpus Striatum; Female; Fetal Hypoxia; Glutamates; Glycolysis; Heart; Hydrogen-Ion Concentration; Lactates; Microdialysis; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Lactate formation from [U-13C]aspartate in cultured astrocytes: compartmentation of pyruvate metabolism.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Immunohistochemistry; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Phosphoenolpyruvate Carboxykinase (ATP); Pyruvic Acid | 1997 |
Cardiac function and glycogen content after twenty-four-hour preservation with various metabolic substrates.
Topics: Animals; Aspartic Acid; Cryopreservation; Glucose; Glycogen; Heart; Male; Myocardium; Organ Preservation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sodium Glutamate | 1998 |
Metabolic modulation of cellular redox potential can improve cardiac recovery from ischemia-reperfusion injury.
Topics: Animals; Aspartic Acid; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Xanthines | 1998 |
In vitro and ex vivo 13C-NMR spectroscopy studies of pyruvate recycling in brain.
Topics: Acetates; Animals; Aspartic Acid; Astrocytes; Brain; Carbon Isotopes; Cells, Cultured; Glutamine; Injections, Intraperitoneal; Injections, Subcutaneous; Magnetic Resonance Spectroscopy; Male; Mice; Pyruvic Acid; Rats; Rats, Wistar | 1998 |
Alanine or pyruvate is required for the development of myotubes from myoblasts and cortisol satisfies this requirement.
Topics: Alanine; Animals; Aspartic Acid; Chick Embryo; Hydrocortisone; Ketoglutaric Acids; Muscle, Skeletal; Pyruvic Acid; Rats | 1999 |
Engineering of a novel biochemical pathway for the biosynthesis of L-2-aminobutyric acid in Escherichia coli K12.
Topics: Acetolactate Synthase; Aminobutyrates; Aspartic Acid; Butyrates; Cloning, Molecular; Escherichia coli; Genetic Engineering; Pyruvic Acid; Recombinant Proteins; Threonine; Threonine Dehydratase; Transaminases | 1999 |
Mutagenesis at asp27 of pyruvate decarboxylase from Zymomonas mobilis. Effect on its ability to form acetoin and acetolactate.
Topics: Acetaldehyde; Acetoin; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Kinetics; Lactates; Models, Chemical; Models, Molecular; Mutation; Protein Conformation; Pyruvate Decarboxylase; Pyruvic Acid; Recombinant Proteins; Zymomonas | 2000 |
Spatial heterogeneity of energy turnover in the heart.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Coronary Circulation; Dogs; Energy Metabolism; Glutamic Acid; Ketoglutaric Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Models, Biological; Myocardium; Oxaloacetic Acid; Oxygen Consumption; Pyruvic Acid | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products.
Topics: Acetaldehyde; Acetoin; Acetolactate Synthase; Alanine; Aspartic Acid; Catalytic Domain; Circular Dichroism; Decarboxylation; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Lactates; Pyruvate Decarboxylase; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Stereoisomerism; Substrate Specificity | 2001 |
Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
Topics: Alanine; Allosteric Regulation; Aniline Compounds; Aspartic Acid; Benzimidazoles; beta-Alanine; Catalysis; Deuterium; Enzyme Activation; Hydroxylamines; Indoles; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Pyruvic Acid; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Titrimetry; Tryptophan Synthase | 2001 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Kidney; Lactic Acid; Maternal Behavior; Microdialysis; Pyruvic Acid; Quinoxalines; Rats; Receptors, Glutamate; Survival Rate; Treatment Outcome | 2001 |
Elucidation of the quantitative significance of pyruvate carboxylation in cultured cerebellar neurons and astrocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Astrocytes; Brain; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Cerebellum; Citric Acid Cycle; Convulsants; Glucose; Lactic Acid; Mice; Neurons; Nitro Compounds; Oxidative Phosphorylation; Propionates; Pyruvic Acid | 2001 |
Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonium Chloride; Animals; Aspartic Acid; Calcium Signaling; Cyclic AMP; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoxanthine; In Vitro Techniques; Inosine; Kidney Tubules; Ligands; Male; Phosphorylation; Pyruvic Acid; Rabbits; Signal Transduction | 2002 |
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies.
Topics: Aspartic Acid; Indicators and Reagents; Osmium Tetroxide; Picolinic Acids; Pyruvic Acid; Stereoisomerism | 2003 |
The urea cycle in the liver of arthritic rats.
Topics: Ammonia; Animals; Arthritis, Experimental; Aspartic Acid; Citrulline; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Kidney; Lactic Acid; Liver; Male; Models, Biological; Oxygen; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Urea | 2003 |
Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution.
Topics: Acetyl Coenzyme A; Arginine; Aspartic Acid; Binding Sites; Candida albicans; Crystallography, X-Ray; Cysteine; Escherichia coli; Kinetics; Malate Synthase; Models, Chemical; Models, Molecular; Mutagenesis; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Isoforms; Pyruvic Acid; Sulfenic Acids; X-Rays | 2003 |
Conversion of acetate and pyruvate to aspartic acid in yeast.
Topics: Acetates; Aspartic Acid; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Yeasts | 1952 |
[Study of the effect of salts of aspartic acid on blood pyruvic acid in ether anesthesia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, General; Aspartic Acid; Ether; Ethers; Humans; Pain Management; Pyruvates; Pyruvic Acid; Salts | 1960 |
The metabolic pattern of the brain in brain perfusion experiments in vivo. II. Pyruvate and lactate formation from C-14-labelled aspartate.
Topics: Aspartic Acid; Brain; Lactates; Lactic Acid; Perfusion; Pyruvates; Pyruvic Acid | 1963 |
EFFECT OF INSULIN IN VITRO ON INCORPORATION OF 14-D FROM PYRUVATE INTO THE PROTEIN OF ISOLATED RAT DIAPHRAGM IN THE PRESENCE OF (12-CALANINE,(12-C)ASPARTIC ACID AND(12-C)GLUTAMIC ACID.
Topics: Alanine; Aspartic Acid; Biological Transport; Carbon Isotopes; Diaphragm; Glutamates; Glutamic Acid; In Vitro Techniques; Insulin; Muscles; Pharmacology; Proteins; Pyruvates; Pyruvic Acid; Rats; Research | 1964 |
CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATE.
Topics: Alanine; Aspartate Aminotransferases; Aspartic Acid; Brain; Carbon Isotopes; Glutamates; Glutamic Acid; Keto Acids; Liver; Lyases; Mitochondria; Oxaloacetates; Pyruvates; Pyruvic Acid; Radiometry; Research | 1965 |
THE OXIDATION OF PYRUVATE BY ISOLATED HEART SARCOSOMES.
Topics: Acetoacetates; Aspartic Acid; Catalysis; Coenzyme A; Glutamates; Glutarates; Malates; Metabolism; Mitochondria; Mitochondria, Muscle; Muscles; Myocardium; Pyruvates; Pyruvic Acid; Rabbits; Rats; Research | 1965 |
BIOSYNTHESIS OF GLUCOSE FROM PYRUVATE-2-C-14 AND ASPARTATE-3-C14 IN A MOLLUSC.
Topics: Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Glucose; Glycogen; Liver; Metabolism; Mollusca; Muscles; Oxaloacetates; Pancreas; Phosphotransferases; Pyruvates; Pyruvic Acid; Research | 1965 |
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate.
Topics: Animals; Aspartic Acid; Carboxy-Lyases; Catalysis; Cattle; Cystathionine gamma-Lyase; Cysteine; Decarboxylation; Kinetics; Neurotransmitter Agents; Oxaloacetates; Pyridoxal Phosphate; Pyruvic Acid; Rabbits; Spectrophotometry; Treponema | 2003 |
A (13)C isotopomer kinetic analysis of cardiac metabolism: influence of altered cytosolic redox and [Ca(2+)](o).
Topics: Animals; Aspartic Acid; Calcium; Carbon Isotopes; Citric Acid Cycle; Cytosol; Glutamic Acid; Heart Rate; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Male; Myocardium; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Pressure; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2004 |
Identification of the catalytic residues involved in the carboxyl transfer of pyruvate carboxylase.
Topics: Acetyl-CoA Carboxylase; Aspartic Acid; Bacillus; Carboxy-Lyases; Carboxyl and Carbamoyl Transferases; Carrier Proteins; Catalytic Domain; Chromatography, Gel; Chromatography, High Pressure Liquid; Circular Dichroism; Conserved Sequence; Enzyme Activation; Fatty Acid Synthase, Type II; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxamic Acid; Protein Structure, Tertiary; Pyruvate Carboxylase; Pyruvic Acid; Tritium | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.
Topics: Anti-Bacterial Agents; Aspartic Acid; Dicarboxylic Acids; Enzyme Inhibitors; Escherichia coli Proteins; Hydro-Lyases; Kinetics; Lysine; Molecular Mimicry; Pyruvic Acid | 2005 |
Contribution of L-3,4-dihydroxyphenylalanine metabolism to the inhibition of gluconeogenesis in rabbit kidney-cortex tubules.
Topics: Alanine; Animals; Aspartic Acid; Caprylates; Depression, Chemical; Dihydroxyacetone; Dopamine; Gluconeogenesis; Glutathione; Glutathione Disulfide; Glycerol; Hydrogen Peroxide; In Vitro Techniques; Kidney Tubules; Levodopa; Male; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvic Acid; Rabbits; Selegiline; Tyramine | 2005 |
Ammonia effects on pyruvate/lactate production in astrocytes--interaction with glutamate.
Topics: Ammonia; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; Glutamine; Glutathione; Glycolysis; Hyperammonemia; Interneurons; Lactic Acid; Malates; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Up-Regulation | 2005 |
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Butyrates; Carbon-Sulfur Lyases; Corynebacterium glutamicum; Gene Deletion; Glutamic Acid; Hemiterpenes; Keto Acids; Phenylpyruvic Acids; Pyruvic Acid; Substrate Specificity; Transaminases | 2005 |
Mechanistic pathways of formation of acrylamide from different amino acids.
Topics: Acrylamide; Acrylamides; Acrylates; Amino Acids; Ammonia; Asparagine; Aspartic Acid; beta-Alanine; Carbohydrates; Carnosine; Creatine; Cysteine; Fructose; Gas Chromatography-Mass Spectrometry; Hydrolysis; Mass Spectrometry; Models, Chemical; Pyruvic Acid; Serine; Time Factors | 2005 |
Pyruvate ameliorates the defect in ureogenesis from ammonia in citrin-deficient mice.
Topics: Amino Acids; Ammonia; Animals; Anticoagulants; Aspartic Acid; Calcium-Binding Proteins; Citric Acid; Citrullinemia; Hyperammonemia; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Organic Anion Transporters; Oxidation-Reduction; Perfusion; Pyruvic Acid; Urea | 2006 |
Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene.
Topics: Aspartic Acid; Autistic Disorder; Chromosome Mapping; DNA Mutational Analysis; DNA Primers; DNA, Mitochondrial; Gene Expression; Gene Frequency; Glutamic Acid; Haplotypes; Humans; Lactic Acid; Membrane Transport Proteins; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Pyruvic Acid | 2006 |
Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism.
Topics: Acetoin; Alanine; Aspartic Acid; Cells, Cultured; Cheese; Diacetyl; Food Microbiology; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lactates; Lactococcus lactis; Metabolism; Pyruvic Acid | 2008 |
Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.
Topics: Allosteric Regulation; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Cloning, Molecular; Enzyme Stability; Genome, Bacterial; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Denaturation; Pyruvic Acid; Recombinant Proteins; Sequence Analysis, Protein; Substrate Specificity; Temperature; Thermoanaerobacter | 2008 |
Probing pyruvate metabolism in normal and mutant fibroblast cell lines using 13C-labeled mass isotopomer analysis and mass spectrometry.
Topics: Aspartic Acid; Carbon Isotopes; Cell Line; Chromatography, Liquid; Citric Acid; Citric Acid Cycle; Fibroblasts; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Malates; Male; Mass Spectrometry; Mutation; Pyruvic Acid | 2009 |
Pyruvate carboxylase plays a crucial role in carbon metabolism of extra- and intracellularly replicating Listeria monocytogenes.
Topics: Animals; Aspartic Acid; Bacterial Proteins; Carbon; Carbon Isotopes; Cell Line; Culture Media; Epithelial Cells; Female; Gene Deletion; Glucose; Glutamic Acid; Humans; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred C57BL; Mutagenesis, Insertional; Oxaloacetic Acid; Pyruvate Carboxylase; Pyruvic Acid; Sepsis; Virulence | 2010 |
Magnetic resonance spectroscopy for evaluation of liposome-encapsulated hemoglobin as a resuscitation fluid.
Topics: Animals; Aspartic Acid; Brain; Cerebral Hemorrhage; Drug Compounding; Energy Metabolism; Feasibility Studies; Hemoglobins; Humans; Lactic Acid; Liposomes; Liquid Ventilation; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2010 |
Biological hydrogen production by the algal biomass Chlorella vulgaris MSU 01 strain isolated from pond sediment.
Topics: Alanine; Anaerobiosis; Aspartic Acid; Biomass; Bioreactors; Carbon; Chlorella vulgaris; Citric Acid; Culture Media; Cysteine; Fermentation; Geologic Sediments; Glucose; Hydrogen; Hydrogen-Ion Concentration; Mannitol; Pyruvic Acid; Succinic Acid | 2011 |
3-Fluoroaspartate and pyruvoyl-dependant aspartate decarboxylase: exploiting the unique characteristics of fluorine to probe reactivity and binding.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carboxy-Lyases; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Conformation; Pyruvic Acid | 2010 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid | 2011 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
Triiodothyronine increases myocardial function and pyruvate entry into the citric acid cycle after reperfusion in a model of infant cardiopulmonary bypass.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cardiac Output; Cardiopulmonary Bypass; Citric Acid Cycle; Decarboxylation; Heart; Hypothermia, Induced; Male; Models, Animal; Myocardial Reperfusion; Myocardium; Oxygen Consumption; Pyruvic Acid; Swine; Triiodothyronine | 2012 |
Cytosolic Ca2+ regulates the energization of isolated brain mitochondria by formation of pyruvate through the malate-aspartate shuttle.
Topics: Animals; Aspartic Acid; Brain; Calcium; Cytosol; Kinetics; Malates; Mice; Mitochondria; Oxidative Phosphorylation; Pyruvic Acid | 2012 |
Functional analysis of the genes encoding diaminopropionate ammonia lyase in Escherichia coli and Salmonella enterica serovar Typhimurium.
Topics: Ammonia-Lyases; Aspartic Acid; beta-Alanine; Carbon; Culture Media; Escherichia coli K12; Gene Deletion; Gene Expression Profiling; Genetic Complementation Test; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Salmonella typhimurium | 2012 |
In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.
Topics: Animals; Aspartic Acid; Carbon Isotopes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Gluconeogenesis; Insulin Resistance; Liver; Magnetic Resonance Spectroscopy; Malates; Male; Mice; Mice, Inbred C57BL; Pyruvate Carboxylase; Pyruvic Acid | 2013 |
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina.
Topics: Animals; Aspartic Acid; Biological Transport; Brain; Citric Acid Cycle; Glutamic Acid; Metabolomics; Mice; Mitochondria; Neurons; Oxygen; Purinones; Pyruvic Acid; Retina | 2013 |
Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse.
Topics: Alanine Transaminase; Amyloid beta-Peptides; Analysis of Variance; Animals; Aspartic Acid; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred BALB C; Nerve Net; Neuronal Plasticity; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Pyruvic Acid; Synapses | 2015 |
Metabolic abnormalities of gastrointestinal mucosa in celiac disease: An in vitro proton nuclear magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Atrophy; Biomarkers; Celiac Disease; Citric Acid Cycle; Duodenum; Female; Glycolysis; Humans; Intestinal Mucosa; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Protons; Pyruvic Acid; Succinic Acid; Young Adult | 2015 |
Residues in the acetyl CoA binding site of pyruvate carboxylase involved in allosteric regulation.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Bicarbonates; Biocatalysis; Glutamic Acid; Kinetics; Magnesium; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutant Proteins; Protein Stability; Pyruvate Carboxylase; Pyruvic Acid; Recombinant Proteins; Rhizobium etli | 2015 |
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Topics: Aspartate Aminotransferase, Cytoplasmic; Aspartic Acid; Cell Proliferation; DNA, Mitochondrial; Electron Transport; Humans; Jurkat Cells; Mitochondria; Mutation; Phenformin; Pyruvic Acid | 2015 |
Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Topics: Adenosine Triphosphate; Aspartic Acid; Butyrates; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Electrons; Humans; Mitochondria; Nucleotides; Pyruvic Acid | 2015 |
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Topics: Animals; Aspartic Acid; Carboxylic Acids; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Immunoblotting; Kidney; Kidney Neoplasms; Male; Metabolomics; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Pyruvate Carboxylase; Pyruvic Acid; RNA Interference; Succinate Dehydrogenase | 2015 |
Major contribution of the type II beta carbonic anhydrase CanB (Cj0237) to the capnophilic growth phenotype of Campylobacter jejuni.
Topics: Aspartic Acid; Bicarbonates; Campylobacter jejuni; Carbon Dioxide; Carbonic Anhydrase II; Culture Media; Lactic Acid; Oxaloacetic Acid; Oxygen; Phenotype; Pyruvate Carboxylase; Pyruvic Acid; Serine | 2016 |
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism.
Topics: Animals; Aspartic Acid; Electron Transport Complex II; Humans; Membrane Proteins; Mice; Mice, Knockout; Neuroendocrine Tumors; Oxidative Phosphorylation; Paraganglioma; Pyruvic Acid; Succinate Dehydrogenase | 2015 |
Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Bridged-Ring Compounds; Catalytic Domain; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Hydro-Lyases; Hydrogen Bonding; Inhibitory Concentration 50; Ketones; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Pyruvic Acid; Recombinant Proteins | 2016 |
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
Topics: Animals; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex I; Homeostasis; Humans; Metformin; Mice, Nude; Mitochondria; NAD; Neoplasms; Pyruvic Acid; Tumor Microenvironment | 2016 |
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine | 2017 |
Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle.
Topics: Ammonia; Aspartic Acid; Carbon Dioxide; Decarboxylation; Glyoxylates; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Malonates; Metabolic Networks and Pathways; Models, Chemical; Origin of Life; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid | 2018 |
Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis.
Topics: Acetyl Coenzyme A; Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Carbon Isotopes; Fatty Acids; Glycolysis; Inflammation; Lactic Acid; Lipopolysaccharides; Liver; Malate Dehydrogenase; Malates; Mitochondria, Liver; Oxidation-Reduction; Palmitic Acid; Pyruvic Acid; Stress, Physiological; Sus scrofa; Swine | 2018 |
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
Topics: Adenosine Triphosphate; Aspartic Acid; Cell Death; Culture Media; Electron Transport Complex I; Fibroblasts; Galactose; Gene Expression; Glycolysis; Humans; Ketoglutaric Acids; Leigh Disease; Malates; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Oxaloacetic Acid; Primary Cell Culture; Pyruvic Acid; Skin | 2018 |
Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.
Topics: Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Citrulline; Citrullinemia; Disease Models, Animal; Glycerolphosphate Dehydrogenase; Hyperammonemia; Intestine, Small; Lactates; Liver; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Membrane Transport Proteins; Organ Specificity; Ornithine; Perfusion; Portal Vein; Pyruvic Acid; Urea | 2019 |
Mitochondrial movement in Aralar/Slc25a12/AGC1 deficient cortical neurons.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aggrecans; Animals; Aspartic Acid; Biological Transport, Active; Calcium; Cerebral Cortex; Glycolysis; Immunohistochemistry; Malates; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Neurons; Oxidative Phosphorylation; Pyruvic Acid | 2019 |
Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply.
Topics: Animals; Aspartic Acid; Brain; Calcium; Calcium Channels; Cytosol; Glutamic Acid; Heart; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Myocardium; Oxidative Phosphorylation; Pyruvic Acid; Rats; Substrate Specificity; Synaptosomes | 2020 |
Hyperpolarized
Topics: Aerobiosis; Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Glioblastoma; Glucose; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Imaging; Metabolomics; Mice, SCID; Pyruvic Acid | 2021 |
Real-time resolution studies of the regulation of pyruvate-dependent lactate metabolism by hexokinases in single cells.
Topics: Aspartic Acid; HEK293 Cells; Hexokinase; Humans; Lactic Acid; Malates; Pyruvic Acid | 2023 |