pyruvaldehyde has been researched along with lysine in 161 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.48) | 18.7374 |
| 1990's | 17 (10.56) | 18.2507 |
| 2000's | 44 (27.33) | 29.6817 |
| 2010's | 60 (37.27) | 24.3611 |
| 2020's | 36 (22.36) | 2.80 |
| Authors | Studies |
|---|---|
| Ladik, J; Otto, P; Szent-Györgyi, A | 1 |
| Szent-Györgyi, A | 1 |
| Kertesz, JC; Laki, K; Szabo, G | 1 |
| Audisio, G; Bonsignore, A; Ferruti, P; Leoncini, G; Zetta, L | 1 |
| Lo, TW; McLellan, AC; Selwood, T; Thornalley, PJ; Westwood, ME | 1 |
| Thornalley, PJ; Westwood, ME | 1 |
| Faust, FM; Nagaraj, RH; Shipanova, IN | 1 |
| Ahmed, MU; Baynes, JW; Brinkmann Frye, E; Degenhardt, TP; Thorpe, SR | 1 |
| Khor, OT; Miyata, T; Osawa, T; Oya, T; Uchida, K; Yasuda, Y | 1 |
| Abordo, EA; Thornalley, PJ | 1 |
| Beisswenger, P; Brownlee, M; Giardino, I; Onorato, J; Shinohara, M; Thornalley, PJ; Thorpe, SR | 1 |
| Baynes, JW; Brinkmann Frye, E; Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Baynes, JW; Degenhardt, TP; Frye, EB; Thorpe, SR | 1 |
| Chana, H; Hipkiss, AR | 1 |
| Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| Baynes, JW; Degenhardt, TP; Thorpe, SR | 1 |
| Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E | 1 |
| Nagaraj, RH; Shamsi, FA | 1 |
| Langborg, A; Minhas, HS; Thornalley, PJ | 1 |
| Klaiber, RG; Lederer, MO | 1 |
| Bucala, R; Kameda, Y; Koike, T; Makita, Z; Suzuki, T; Takeuchi, M | 1 |
| Gombás, J; Kolev, K; Léránt, I; Machovich, R | 1 |
| Brownson, C; Hipkiss, AR | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A | 1 |
| Arnold, BM; Chellan, P; Nagaraj, RH; Wilker, SC | 1 |
| Kamiya, H; Murata-Kamiya, N | 1 |
| Bank, RA; Baynes, JW; Ben, ZC; Bijlsma, JW; Brau-Benjamin, O; DeGroot, J; Lafeber, FP; Maroudas, A; Mizrahi, J; Schalkwijk, CG; TeKoppele, JM; Thorpe, SR; Verzijl, N | 1 |
| Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M | 1 |
| Biemel, KM; Lederer, MO; Mally, A; Nagaraj, RH; Padayatti, PS; Sarkar, P | 1 |
| Akagawa, M; Sasaki, T; Suyama, K | 1 |
| Cai, W; Crandall, J; Dardaine, V; Goldberg, T; Oberstein, R; Peppa, M; Rayfield, EJ; Vlassara, H | 1 |
| Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M | 1 |
| Berg, TJ; Birkeland, KI; Brownlee, M; Giardino, I; Hanssen, KF; Kilhovd, BK; Thornalley, PJ; Torjesen, PA | 1 |
| Biswas, J; Kumar, SK; Miriam, KC; Nagaraj, RH; Ramakrishnan, S; Sulochana, KN; Swamy-Mruthinti, S | 1 |
| Araki, T; Hayase, F; Hayashi, CM; Horiuchi, S; Nagai, R | 1 |
| Hattori, M; He, C; McEvoy, R; Peppa, M; Vlassara, H; Zheng, F | 1 |
| Baliga, S; Cai, W; Goldberg, T; Lu, M; Peppa, M; Uribarri, J; Vassalotti, JA; Vlassara, H | 1 |
| Crabb, JW; Kumar, R; Levison, B; Mehta, S; Nagaraj, RH; Oya-Ito, T; Padayatti, PS; Padival, AK; Sun, J; West, K | 1 |
| Kang, JH | 2 |
| Ahmed, N; Dawczynski, J; Franke, S; Haik, GM; Stein, G; Strobel, J; Thornalley, PJ | 1 |
| Ahmed, N; Häussinger, D; Heidland, A; Lüthen, R; Schinzel, R; Sebekova, K; Thornalley, PJ; Voelker, W | 1 |
| Lapolla, A; Ragazzi, E; Reitano, R; Sartore, G; Seraglia, R; Traldi, P | 1 |
| Hoekman, K; Niessen, HW; Schalkwijk, CG; van Heijst, JW | 1 |
| Engelse, M; Lieuw-a-Fa, ML; Schalkwijk, CG; van Hinsbergh, VW | 1 |
| Funk, RH; Knels, L; Kniep, EM; Ozkucur, N; Reber, F; Roehlecke, C; Steinberg, A | 1 |
| Linetsky, MD; Shipova, EV | 1 |
| Gratzer, PF; Lee, JM; Santerre, JP | 1 |
| Nagaraj, RH; Padival, S | 1 |
| Arora, PD; Chong, SA; Laschinger, C; Lee, W; Manolson, M; McCulloch, CA; Simmons, CA; Sodek, J; Young, EW | 1 |
| Biswas, A; Nagaraj, RH; Puttaiah, S; Staniszewska, M | 1 |
| Cai, W; Ferrucci, L; Goodman, S; Peppa, M; Striker, G; Uribarri, J; Vlassara, H | 1 |
| Sivakami, S; Suji, G | 1 |
| Cai, W; Chen, X; He, JC; Striker, GE; Vlassara, H; Zhu, L | 1 |
| Fujiwara, Y; Mera, K; Nagai, R; Sakashita, N; Takeya, M; Yamagata, K | 1 |
| Cai, W; He, JC; Li, Z; Linden, E; Uribarri, J; Vlassara, H; Winston, J; Xue, C | 1 |
| Chang, T; Desai, K; Jia, X; Wang, X; Wu, L | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP | 1 |
| Desai, K; Dhar, A; Kazachmov, M; Wu, L; Yu, P | 1 |
| Gubkina, SA; Kumskova, EM; Lankin, VZ; Ruuge, EK; Shepelkova, GS; Shumaev, KB | 1 |
| Davidge, ST; Jiang, Y; Sankaralingam, S; Sawamura, T; Xu, H | 1 |
| Chaudhuri, BS; Ray, M; Ray, S; Talukdar, D | 1 |
| Cai, W; Chen, X; He, JC; Striker, GE; Torreggiani, M; Vlassara, H; Zhu, L | 1 |
| Cai, W; Chen, X; Mericq, V; Piccardo, C; Striker, GE; Uribarri, J; Vlassara, H; Zhu, L | 1 |
| Assunção, NA; Bechara, EJ; Massari, J; Tavares, MF; Tokikawa, R; Zanolli, L | 1 |
| Chan, LY; Cheng, AS; Lai, KN; Lan, HY; Leung, JC; Lin, M; Tang, SC | 1 |
| Diema, C; Estelrich, J; Flores-Morales, P; Gutiérrez-Oliva, S; Luque, FJ; Silva, E; Toro-Labbé, A; Vilaseca, M | 1 |
| Ahmad, S; Alam, K; Ali, A; Dixit, K; Shahab, U | 1 |
| Chen, F; Ma, J; Peng, X; Wang, M; Zhang, X | 1 |
| Babizhayev, MA; Deyev, AI; Lankin, VZ; Savel'yeva, EL; Yegorov, YE | 1 |
| Glomb, MA; Salzwedel, G; Spanneberg, R | 1 |
| Field, MJ; Moosavi-Movahedi, AA; Nasiri, R; Zahedi, M | 1 |
| Chang, CT; Chang, YM; Chen, SM; Huang, TC; Huang, YP; Lee, JA; Li, YC; Tsai, SH | 1 |
| Dai, H; Li, W; Ni, Z; Xu, H; Zhang, Z; Zhuge, Z | 1 |
| Abetew, D; Christianson, C; Enquobahrie, DA; Hevner, K; Qiu, CF; Sheaff, C; Williams, MA; Zimmer, J | 1 |
| Lee, JA; Li, YC; Shih, YM | 1 |
| Cai, W; Castillo, A; Gallardo, M; Landy, DC; Livingstone, A; Manning, R; Namias, N; Schulman, CI; Striker, GE; Uribarri, J; Vlassara, H | 1 |
| An, SH; Kang, JH | 1 |
| Gubkina, SA; Kosmachevskaya, OV; Nasybullina, EI; Shumaev, KB; Topunov, AF | 1 |
| Dahl-Jørgensen, K; Fagerland, MW; Hanssen, KF; Jørum, E; Karimé, B; Mellgren, SI; Monnier, VM; Sveen, KA | 1 |
| Barzilay, JI; Fonseca, V; Goldfine, AB; Jablonski, KA; Monnier, VM; Shoelson, SE; Strauch, C | 1 |
| Miller, CB; Szwergold, BS | 1 |
| Brimble, MA; Cooper, GJ; Harris, PW; Kamalov, M | 1 |
| Millsap, AD; Petrova, KV; Rizzo, CJ; Stec, DF | 1 |
| Chen, SM; Huang, TC; Lee, JA; Li, YC | 1 |
| Bui, LC; Dairou, J; Lamouri, A; Leger, T; Mihoub, M; Richarme, G | 1 |
| Augner, K; Eichler, J; Pischetsrieder, M; Utz, W | 1 |
| Cai, W; Díaz-Cisneros, FJ; Garay-Sevilla, ME; Macías-Cervantes, MH; Rodríguez-Soto, JM; Uribarri, J | 1 |
| Poretsky, L; Striker, GE; Vlassara, H; Woodward, M; Yubero-Serrano, EM | 1 |
| Abdallah, J; Dairou, J; Gontero, B; Mihoub, M; Richarme, G | 1 |
| Cleary, PA; Gao, X; Genuth, S; Lachin, JM; Monnier, VM; Sell, DR; Sun, W | 1 |
| Battú, CE; Broetto, N; Dutra, MF; Galland, F; Gonçalves, CA; Hansen, F; Lirio, F; Nardin, P | 1 |
| Alam, K; Ali, A; Habib, S; Khan, F; Mir, AR | 1 |
| Ali, A; Habib, S; Mir, AR; Siddiqui, SS | 1 |
| Ahmedna, M; Sampath, C; Sang, S; Zhu, Y | 1 |
| Gökmen, V; Hamzalıoğlu, A | 1 |
| Chand, V; Cooper, ME; de Courten, B; de Courten, MP; Dougherty, SL; Forbes, JM; Kingwell, BA; Schalkwijk, CG; Scheijen, JL; Schlaich, M; Soldatos, G; Sourris, KC; Straznicky, N; Walker, KZ | 1 |
| Brings, S; Ejdesjö, A; Eriksson, UJ; Fleming, T; Fred, RG; Nawroth, PP | 1 |
| Beelman, RB; Cai, W; Calvo, MS; Goh, BC; Kalaras, MD; Mehrotra, A; Nadkarni, G; Uribarri, J; Wang, L | 1 |
| Beisswenger, PJ; Howell, S; Knowler, WC; Lemley, KV; Mauer, M; Nelson, RG; Saulnier, PJ; Tanamas, SK; Weil, EJ; Wheelock, KM; Yee, B | 1 |
| Morales, FJ; Navarro, M | 2 |
| Huang, J; Ou, J; Ou, S; Wang, M | 1 |
| Xu, XB; Yu, P; Yu, SJ | 1 |
| Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC | 1 |
| Liu, G; Lu, Y; Lv, L; Sang, S; Xia, Q; Zheng, T | 1 |
| Alizadeh, M; Kheirouri, S | 1 |
| Dai, S; Dong, Q; Feng, C; Li, X; Wu, Z; Yang, L; Zhang, T | 1 |
| Afsar, M; Al-Bagmi, MS; Bano, B; Bhat, SA; Bhat, WF; Khan, MS | 1 |
| Ahmed, N; Brison, D; Carroll, M; McNeil, L; Murgatroyd, C; Nevin, C | 1 |
| Chang, CK; Chen, ME; Chen, WA; Chun, MC; How, SC; Li, CT; Lo, CH; Wang, SS; Wu, JW | 1 |
| Alfonso, H; Almeida, OP; Davis, TME; Flicker, L; Forbes, J; Golledge, J; Hankey, GJ; Irrgang, F; Lamb, LS; Müench, G; Norman, PE; Yeap, BB | 1 |
| Blair, CA; Campbell, KS; Holewinski, RJ; Kirk, JA; Li, A; Martin, TG; Moravec, CS; Papadaki, M; Previs, SB; Stachowski, MJ; Van Eyk, JE; Warshaw, DM | 1 |
| Nakaya, I; Nakayama, K; Nakayama, M; Soma, J; Tezuka, Y; Yahata, M | 1 |
| Gökmen, V; Taş, NG | 1 |
| Chen, J; Gao, D; He, Z; Jiao, Y; Qin, F; Quan, W; Zeng, M | 1 |
| Ganesh, D; Kobori, T; Kumano-Kuramochi, M; Machida, S; Torigoe, K | 1 |
| Dong, L; Wang, S; Wang, W; Wu, Y; Zhang, Y | 1 |
| Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S | 1 |
| Lund, MN; Olsen, K; Poojary, MM; Ray, CA; Zhang, W | 1 |
| Chen, J; Gao, D; He, J; He, Z; Jiao, Y; Qin, F; Xie, M; Zeng, M | 1 |
| Ahmad, S; Alatar, AA; Faisal, M; Rehman, S | 1 |
| Anderson, CC; Chapman, E; Gaffney, DO; Galligan, JJ; Jennings, EQ; Johannsen, M; Marentette, JO; Roede, JR; Schou Oxvig, AM; Shi, T; Spiegel, DA; Streeter, MD | 1 |
| Carganico, S; Gallo, A; Lapolla, A; Nuti, F; Papini, AM; Piarulli, F; Real-Fernandez, F; Rentier, C; Rossi, G; Rovero, P; Traldi, P | 1 |
| Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y | 1 |
| Cardelo, MP; de la Cruz-Ares, S; García-Rios, A; Gutiérrez-Mariscal, FM; Katsiki, N; López-Miranda, J; Malagón, MM; Pérez-Martínez, P; Torres-Peña, JD; Yubero-Serrano, EM | 1 |
| Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q | 1 |
| Abd-Elrahman, AA; Khalifa, I; Li, B; Liang, H; Shen, Q; Sobhy, R | 1 |
| Bast, A; Opperhuizen, A; van der Lugt, T; van Leeuwen, S; Venema, K; Vrolijk, MF | 1 |
| Chen, J; He, Z; Jiao, Y; Li, Y; Liu, G; Qin, F; Quan, W; Wang, Z; Xue, C; Zeng, M | 1 |
| Ye, Y; Zhang, B; Zhang, W; Zhu, H | 1 |
| Alizadeh, M; Esmaeili, F; Kheirouri, S; Maleki, V | 1 |
| Choi, S; Fica-Contreras, SM; Hedges, JS; Henning, NJ; Shuster, SO | 1 |
| Gu, MJ; Ha, SK; Kim, Y; Lee, HW; Lee, JY; Lee, S | 1 |
| Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U | 1 |
| Kanzler, C; Rohn, S; Wustrack, F | 1 |
| Banerjee, S | 1 |
| Inoue, Y; Iwai, M; Kadoyama, K; Matsumoto, K; Nitta, Y; Takano-Ohmuro, H; Takasugi, R; Takenokuchi, M; Taniguchi, T; Yoshida, K | 1 |
| Jakhotia, S; Reddy Addi, U; Reddy, GB; Reddy, SS | 1 |
| Baskal, S; Tsikas, D | 1 |
| Agostini, HT; Betting, F; Martin, G; Schlunck, G | 1 |
| Akıllıoğlu, HG; Chatterton, DEW; Lund, MN | 1 |
| Ibarra, I; Martinez-Peon, D; Que-Salinas, U; Reyes-Figueroa, AD; Scheckhuber, CQ | 1 |
| Eggen, MD; Glomb, MA; Merboth, P; Neukirchner, H | 1 |
| Groß, J; Henle, T; Pätzold, S; Treibmann, S | 1 |
| Cunha, MP; Dafre, AL; de Almeida, GRL; Selhorst, I; Szczepanik, JC | 1 |
| Avrameas, A; Ceci, M; Cojean, C; Cornacchione, V; de Roche, R; Florencia, EF; Gass, SK; Gaulis, S; Goetschy, JF; Gudjonsson, JE; Hofmann, A; Lehmann, JCU; Loesche, C; Macchiarella, G; Meschberger, P; Naumann, U; Oetliker-Contin, S; Osinga, R; Prens, EP; Riker, J; Roediger, B; Röhn, TA; Roth, L; Schaefer, DJ; Schubart, A; Te, H; Traggiai, E; Wang, Y; Wettstein-Ling, B; Wieczorek, G; Wollschlegel, A | 1 |
| Cao, B; Fan, L; Hu, X; Wang, M; Yu, W; Zhang, B | 1 |
| Davies, MJ; Fuentes-Lemus, E; López-Alarcón, C; Reyes, JS | 1 |
| Keipert, S; Klaus, S; Masania, J; Ost, M; Rabbani, N; Thornalley, PJ; Wijten, P | 1 |
| Deng, Y; Huang, L; Wang, X; Xie, P; Zhang, C; Zhang, Y | 1 |
| Ha, SK; Jeong, YJ; Kang, J; Lee, HH; Lee, KW | 1 |
| Kosmachevskaya, OV; Nasybullina, EI; Ruuge, EK; Shumaev, KB; Topunov, AF | 1 |
| de Graaf, MCG; Feskens, EJM; Jonkers, DMAE; Keszthelyi, D; Mujagic, Z; Pierik, MJ; Schalkwijk, CG; Scheijen, JLJM; Spooren, CEGM | 1 |
| Ho, CT; Huang, SF; Hung, WL; Liao, KW; Lin, YY | 1 |
| Jiang, Y; Jie, RQD; Li, C; Li, H; Li, JX; Yu, J; Zhang, Y; Zhao, Y; Zulewska, J | 1 |
| Li, J; Sun, X; Yan, S | 1 |
| Chang, H; Chen, J; Chen, Q; Deng, P; He, Z; Oz, E; Oz, F; Qin, F; Wang, Q; Wang, Z; Zeng, M | 1 |
2 review(s) available for pyruvaldehyde and lysine
| Article | Year |
|---|---|
Curcumin against advanced glycation end products (AGEs) and AGEs-induced detrimental agents.
Topics: Animals; Antioxidants; Apoptosis; Arginine; Cell Death; Cell Proliferation; Curcumin; Databases, Factual; DNA Damage; Glycation End Products, Advanced; Humans; Lysine; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Receptor for Advanced Glycation End Products | 2019 |
The expanding impact of methylglyoxal on behavior-related disorders.
Topics: Arginine; Cysteine; Dopamine; Glycation End Products, Advanced; Humans; Lysine; Magnesium Oxide; Mental Disorders; Nucleotides; Pain; Pyruvaldehyde | 2023 |
12 trial(s) available for pyruvaldehyde and lysine
| Article | Year |
|---|---|
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors | 2000 |
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food Analysis; Food, Formulated; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lipid Peroxidation; Lysine; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde | 2003 |
Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and
Topics: Adolescent; Adult; Aged; Carnosine; Ceruloplasmin; Dermatologic Agents; Diabetes Complications; Double-Blind Method; Female; Free Radicals; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Schiff Bases; Skin Aging; Skin Diseases; Young Adult | 2012 |
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates | 2014 |
Effect of an advanced glycation end product-restricted diet and exercise on metabolic parameters in adult overweight men.
Topics: Adipose Tissue; Adult; Blood Glucose; Body Mass Index; Diet; Diet, Reducing; Energy Intake; Exercise; Feeding Behavior; Glycation End Products, Advanced; Humans; Lipids; Lipoproteins, HDL; Lysine; Male; Middle Aged; Obesity; Overweight; Oxygen Consumption; Pyruvaldehyde; Triglycerides; Waist Circumference; Weight Loss | 2015 |
Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.
Topics: Adiponectin; Age Factors; Aged; Albuminuria; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Estrogen Receptor alpha; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Intention to Treat Analysis; Lysine; Male; Metformin; Middle Aged; NF-E2-Related Factor 2; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sevelamer; Sex Factors; Single-Blind Method; Sirtuin 1; White People | 2015 |
Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes.
Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Biopsy; Cardiovascular Diseases; Carotid Artery Diseases; Carotid Intima-Media Thickness; Chi-Square Distribution; Collagen; Coronary Artery Disease; Diabetes Mellitus, Type 1; Disease Progression; Female; Glycation End Products, Advanced; Glycosylation; Heart Diseases; Humans; Logistic Models; Lysine; Magnetic Resonance Imaging; Male; Multivariate Analysis; Odds Ratio; Pepsin A; Pyruvaldehyde; Risk Factors; Skin; Time Factors; Vascular Calcification; Young Adult | 2015 |
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial.
Topics: Adult; Blood Glucose; Cross-Over Studies; Diet; Double-Blind Method; Female; Glucose Clamp Technique; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Imidazolidines; Insulin; Insulin Resistance; Lysine; Male; Middle Aged; Overweight; Pyruvaldehyde | 2016 |
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Imidazoles; Indians, North American; Kidney; Kidney Glomerulus; Losartan; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pyruvaldehyde | 2016 |
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study.
Topics: Biomarkers; Carotid Artery Diseases; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Endothelium, Vascular; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Olive Oil; Pyruvaldehyde; Single-Blind Method; Vasodilation | 2020 |
The Effects of Taurine Supplementation on Metabolic Profiles, Pentosidine, Soluble Receptor of Advanced Glycation End Products and Methylglyoxal in Adults With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Metabolome; Prognosis; Pyruvaldehyde; Taurine | 2021 |
147 other study(ies) available for pyruvaldehyde and lysine
| Article | Year |
|---|---|
Quantum chemical calculations of model systems for ascorbic acid adducts with Schiff bases of lysine side chains: possibility of internal charge transfer in proteins.
Topics: Ascorbic Acid; Electron Transport; Lysine; Models, Chemical; Models, Molecular; Proteins; Pyruvaldehyde; Schiff Bases | 1979 |
The living state and cancer.
Topics: Aldehydes; Ascorbic Acid; Biological Evolution; Chemical Phenomena; Chemistry; Electric Conductivity; Electron Spin Resonance Spectroscopy; Electron Transport; Ethylenediamines; Glutathione; Lysine; Methylamines; Mixed Function Oxygenases; Neoplasms; Origin of Life; Oxygen; Proteins; Pyruvaldehyde | 1980 |
Interaction of methylglyoxal with poly-L-lysine.
Topics: Aldehydes; Electron Spin Resonance Spectroscopy; Lysine; Magnetic Resonance Spectroscopy; Peptides; Polylysine; Pyruvaldehyde | 1980 |
The structure of the polymer formed from methylglyoxal in the presence of L(+)-lysine.
Topics: Aldehydes; Chemical Phenomena; Chemistry; Chemistry, Physical; Lysine; Polymers; Pyruvaldehyde | 1981 |
Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
Topics: Acetylcysteine; Arginine; Kinetics; Lysine; Protein Binding; Pyruvaldehyde; Serum Albumin, Bovine | 1994 |
Molecular characteristics of methylglyoxal-modified bovine and human serum albumins. Comparison with glucose-derived advanced glycation endproduct-modified serum albumins.
Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glucose; Glycation End Products, Advanced; Humans; Lysine; Molecular Weight; Pyruvaldehyde; Serum Albumin; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence | 1995 |
Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal.
Topics: Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Pyruvaldehyde; Spectrometry, Mass, Fast Atom Bombardment | 1996 |
N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbohydrate Metabolism; Child; Collagen; Crystallins; Humans; Lens, Crystalline; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Ribonucleases; Skin | 1997 |
Protein modification by a Maillard reaction intermediate methylglyoxal. Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo.
Topics: Animals; Antibodies; Aorta; Arginine; Arteriosclerosis; Hemocyanins; Humans; Imidazoles; Lysine; Maillard Reaction; Molecular Structure; Pyruvaldehyde; Rabbits; Serum Albumin, Bovine | 1997 |
Synthesis and secretion of tumour necrosis factor-alpha by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts.
Topics: Arginine; Chemotaxis, Leukocyte; Cystine; Glycation End Products, Advanced; Humans; Lysine; Monocytes; Pyruvaldehyde; Serum Albumin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
Topics: Acetone; Aldehydes; Animals; Cattle; Endocytosis; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Glycation End Products, Advanced; Glyoxal; Hyperglycemia; Ketones; Lactic Acid; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Transfection; Tumor Cells, Cultured | 1998 |
Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: evidence for increased oxidative stress in uremia.
Topics: Cross-Linking Reagents; Female; Glyoxal; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Mass Spectrometry; Middle Aged; Oxidative Stress; Pyruvaldehyde; Uremia | 1998 |
Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.
Topics: Aging; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; In Vitro Techniques; Lysine; Maillard Reaction; Pyruvaldehyde; Ribonucleases | 1998 |
Carnosine protects proteins against methylglyoxal-mediated modifications.
Topics: Carnosine; Crystallins; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Lysine; Ovalbumin; Pyruvaldehyde | 1998 |
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia | 1998 |
Chemical modification of proteins by methylglyoxal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia | 1998 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.
Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Leukocyte Common Antigens; Lysine; Male; Middle Aged; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyruvaldehyde; Risk Factors; T-Lymphocytes | 1999 |
Immunochemical detection of dicarbonyl-derived imidazolium protein crosslinks in human lenses.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies; Antibody Specificity; Binding, Competitive; Cataract; Cattle; Cellular Senescence; Crystallins; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Immunohistochemistry; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Pyruvaldehyde | 1999 |
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin | 1999 |
Cross-linking of proteins by Maillard processes: characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxal.
Topics: Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Glyoxal; Imidazoles; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Pyruvaldehyde; Serum Albumin, Bovine | 1999 |
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glyceraldehyde; Glyoxal; Humans; Immunoblotting; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidation-Reduction; Pyruvaldehyde; Rabbits; Renal Dialysis | 2000 |
Modulation of plasminogen activation and plasmin activity by methylglyoxal modification of the zymogen.
Topics: Animals; Arginine; Catalysis; Electrophoresis, Polyacrylamide Gel; Fibrinolysin; Fibrinolysis; Kinetics; Lysine; Male; Plasminogen; Pyruvaldehyde; Rats; Rats, Wistar; Spectrometry, Fluorescence | 2000 |
Carnosine reacts with a glycated protein.
Topics: Aging; Animals; Carnosine; Glycoproteins; Glycosylation; Humans; In Vitro Techniques; Lysine; Ovalbumin; Oxidation-Reduction; Pyruvaldehyde | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Arginine; Blood Proteins; Diabetes Mellitus; Humans; Lens, Crystalline; Lysine; Middle Aged; Ornithine; Pyrimidines; Pyruvaldehyde | 2001 |
Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.
Topics: Acetylcysteine; Base Sequence; Binding Sites; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Lysine; Pyruvaldehyde; Reducing Agents; Substrate Specificity; Templates, Genetic | 2001 |
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses | 2002 |
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2002 |
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Diabetes Mellitus, Experimental; Dimerization; Erythrocytes; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Chemical; Oxidative Stress; Pyridoxamine; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2002 |
Oxidative deamination of lysine residue in plasma protein of diabetic rats. Novel mechanism via the Maillard reaction.
Topics: 2-Aminoadipic Acid; Animals; Blood Proteins; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Copper; Diabetes Mellitus, Experimental; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Maillard Reaction; Male; Models, Chemical; Oxidation-Reduction; Oxygen; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Temperature; Time Factors | 2002 |
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Humans; Imidazoles; Immunoassay; Lysine; Pyruvaldehyde; Sensitivity and Specificity | 2003 |
Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization.
Topics: Adolescent; Adult; Blood Glucose; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Epiretinal Membrane; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Pyruvaldehyde; Retinal Neovascularization; Retinal Vasculitis | 2002 |
Identification of N epsilon-(carboxyethyl)lysine, one of the methylglyoxal-derived AGE structures, in glucose-modified protein: mechanism for protein modification by reactive aldehydes.
Topics: Aldehydes; Chromatography, High Pressure Liquid; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Pyruvaldehyde; Serum Albumin, Bovine | 2003 |
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.
Topics: Administration, Oral; Aging; Albuminuria; Animals; Animals, Newborn; Blood Glucose; Creatinine; Crosses, Genetic; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Islets of Langerhans; Lysine; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvaldehyde | 2003 |
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia | 2003 |
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification.
Topics: Alcohol Dehydrogenase; alpha-Crystallins; Anilino Naphthalenesulfonates; Animals; Arginine; Ascorbic Acid; Cattle; Citrate (si)-Synthase; Humans; Insulin; Lens, Crystalline; Lysine; Middle Aged; Molecular Chaperones; Monosaccharides; Ornithine; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Pyruvaldehyde | 2003 |
Oxidative damage of DNA induced by methylglyoxal in vitro.
Topics: Catalase; Chelating Agents; Copper; DNA; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Lysine; Plasmids; Pyruvaldehyde; Superoxides | 2003 |
Oxidative damage of DNA by the reaction of amino acid with methylglyoxal in the presence of Fe(III).
Topics: Catalase; Deferoxamine; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Iron; Iron Chelating Agents; Lysine; Plasmids; Pyruvaldehyde; Superoxides | 2003 |
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins.
Topics: Aged; Arginine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Female; Fluorometry; Glycation End Products, Advanced; Humans; Hydrolysis; Imidazoles; Lens, Crystalline; Lysine; Male; Mass Spectrometry; Middle Aged; Pyruvaldehyde | 2003 |
Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis.
Topics: Adult; Aged; Biomarkers; Blood Proteins; Case-Control Studies; Female; Glycation End Products, Advanced; Glycosylation; Humans; Liver; Liver Cirrhosis; Lysine; Male; Middle Aged; Nitrosation; Osmolar Concentration; Oxidation-Reduction; Pyruvaldehyde | 2004 |
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress.
Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dialysis Solutions; Glycated Hemoglobin; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde | 2005 |
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine.
Topics: Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycolysis; Humans; Lysine; Neoplasm Proteins; Neoplasms; Pyruvaldehyde | 2005 |
Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs.
Topics: Alternative Splicing; Cell Adhesion Molecules; Endothelial Cells; Endothelium, Vascular; Glycation End Products, Advanced; Humans; Lysine; Macrophages; Protein Isoforms; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin | 2006 |
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
Topics: Animals; Annexin A5; Apoptosis; Carbonic Anhydrase Inhibitors; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Flow Cytometry; Glyoxal; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Lysine; Neurons; Neuroprotective Agents; Pyruvaldehyde; Rats; Reactive Oxygen Species; Retina; Sulfonamides; Thiophenes | 2006 |
Convenient synthesis of GOLD and MOLD and identification of their oxidation products in vitro and in vivo.
Topics: Acetic Acid; Animals; Cataract; Chemistry; Chromatography, Liquid; Crystallins; Hydrogen Peroxide; Hydrolysis; Imidazoles; Lysine; Mass Spectrometry; Models, Chemical; Oxygen; Pyruvaldehyde; Temperature; Time Factors | 2007 |
The effect of chemical modification of amino acid side-chains on collagen degradation by enzymes.
Topics: Amino Acids; Animals; Arginine; Biocompatible Materials; Cattle; Chromatography, Gel; Collagen Type I; Endopeptidases; Epoxy Compounds; Lysine; Propanols; Pyruvaldehyde; Solubility | 2007 |
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lens Diseases; Lens, Crystalline; Lysine; Maillard Reaction; Male; Organ Culture Techniques; Ornithine; Pyridoxamine; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 2006 |
Methylglyoxal inhibits the binding step of collagen phagocytosis.
Topics: Amino Acids; Animals; Arginine; Cell Adhesion; Collagen; Fibroblasts; Humans; Integrin alpha2beta1; Lysine; Periodontitis; Phagocytosis; Protein Binding; Pyruvaldehyde; Rats; Signal Transduction | 2007 |
Methylglyoxal inhibits glycation-mediated loss in chaperone function and synthesis of pentosidine in alpha-crystallin.
Topics: alpha-Crystallins; Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eye Proteins; Glycosylation; Lens, Crystalline; Lysine; Molecular Chaperones; Organ Culture Techniques; Pyruvaldehyde; Rats | 2007 |
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; C-Reactive Protein; Diet; Dinoprost; Energy Intake; Female; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lysine; Male; Middle Aged; Oxidative Stress; Pyruvaldehyde | 2007 |
DNA damage during glycation of lysine by methylglyoxal: assessment of vitamins in preventing damage.
Topics: Amino Acids; DNA Damage; Free Radical Scavengers; Glycation End Products, Advanced; Glycosylation; Iron; Lysine; Plasmids; Pyridoxal Phosphate; Pyruvaldehyde; Superoxides; Vitamins | 2007 |
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Antioxidants; Cell Line; Chromones; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glycation End Products, Advanced; Humans; Lysine; Morpholines; Mutation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; RNA, Small Interfering; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxide Dismutase; Transfection | 2008 |
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody.
Topics: Aldehydes; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Cattle; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Kidney; Lysine; Male; Pyruvaldehyde; Rats; Rats, Wistar; Sensitivity and Specificity; Serum Albumin | 2008 |
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation.
Topics: Adult; Aged; Case-Control Studies; Cells, Cultured; Cross-Sectional Studies; Endothelial Cells; Endothelium, Vascular; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hyperemia; Lysine; Male; Middle Aged; Nitric Oxide Synthase Type III; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regional Blood Flow; Renal Insufficiency, Chronic; RNA Interference; RNA, Messenger; RNA, Small Interfering; Severity of Illness Index; Skin; Up-Regulation | 2008 |
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats.
Topics: Animals; Aorta; Dietary Carbohydrates; Fructose; Glutathione; Glycation End Products, Advanced; Hydrogen Peroxide; Hypertension; Hypoglycemic Agents; Lysine; Male; Mesenteric Arteries; Metformin; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 2008 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin | 2008 |
Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors.
Topics: Acetone; Animals; Aorta; Cell Line; Fructose; Glucose; Lysine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Peroxynitrous Acid; Pyruvaldehyde; Rats | 2008 |
Superoxide formation as a result of interaction of L-lysine with dicarbonyl compounds and its possible mechanism.
Topics: Electron Spin Resonance Spectroscopy; Lysine; Oxidation-Reduction; Pyruvaldehyde; Superoxides | 2009 |
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase.
Topics: Adult; Arginase; Arteries; Case-Control Studies; Cells, Cultured; Endothelium, Vascular; Female; Glutathione Peroxidase; Glutathione Reductase; Humans; Lactoylglutathione Lyase; Lysine; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Pre-Eclampsia; Pregnancy; Pyruvaldehyde; Scavenger Receptors, Class E; Thiolester Hydrolases | 2009 |
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delivery Systems; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidative Stress; Protein Conformation; Protein Folding; Pyruvaldehyde; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serum Albumin | 2009 |
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease.
Topics: Active Transport, Cell Nucleus; Age Factors; Animals; Cell Line; Endothelial Cells; ErbB Receptors; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein Kinase C-delta; Protein Subunits; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; Signal Transduction; Time Factors; Transcription Factor RelA; Transfection; Vascular Diseases | 2010 |
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?
Topics: Adiponectin; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Infant; Infant Food; Infant, Newborn; Insulin; Isoprostanes; Lysine; Pyruvaldehyde; Risk Factors; Young Adult | 2010 |
Acetyl radical production by the methylglyoxal-peroxynitrite system: a possible route for L-lysine acetylation.
Topics: Acetylation; Electron Spin Resonance Spectroscopy; Electrophoresis, Capillary; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysine; Peroxynitrous Acid; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization; Temperature | 2010 |
Differential effects of advanced glycation end-products on renal tubular cell inflammation.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Connective Tissue Growth Factor; Epithelial Cells; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Interleukin-6; Kidney Tubules, Proximal; Lysine; Nephritis, Interstitial; NF-kappa B; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rosiglitazone; Serum Albumin; Serum Albumin, Bovine; Signal Transduction; Thiazolidinediones; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2011 |
Enhanced reactivity of Lys182 explains the limited efficacy of biogenic amines in preventing the inactivation of glucose-6-phosphate dehydrogenase by methylglyoxal.
Topics: Biogenic Amines; Enzyme Activation; Glucosephosphate Dehydrogenase; Hydrogen-Ion Concentration; Kinetics; Lysine; Mass Spectrometry; Pyruvaldehyde | 2011 |
Genotoxicity and immunogenicity of DNA-advanced glycation end products formed by methylglyoxal and lysine in presence of Cu2+.
Topics: Animals; Copper; DNA; DNA Damage; Female; Glycation End Products, Advanced; Humans; Lysine; Pyruvaldehyde; Rabbits | 2011 |
Dual effects of phloretin and phloridzin on the glycation induced by methylglyoxal in model systems.
Topics: Acetylcysteine; Amino Acid Sequence; Arginine; Creatine Kinase; Lysine; Models, Molecular; Peptides; Phloretin; Phlorhizin; Protein Binding; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization | 2011 |
Formation of early and advanced Maillard reaction products correlates to the ripening of cheese.
Topics: Caseins; Cheese; Chymosin; Food Handling; Food Technology; Lysine; Maillard Reaction; Protein Modification, Translational; Pyruvaldehyde; Time Factors | 2012 |
Comparative DFT study to determine if α-oxoaldehydes are precursors for pentosidine formation.
Topics: Arginine; Glycosylation; Glyoxal; Imidazoles; Kinetics; Lysine; Molecular Structure; Pyruvaldehyde; Quantum Theory; Schiff Bases; Thermodynamics; Water | 2012 |
Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: an important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy.
Topics: Animals; Aristolochic Acids; Creatine; Disease Models, Animal; Female; Kidney; Lysine; Mice; Mice, Inbred C3H; Nephritis, Interstitial; Pyruvaldehyde | 2012 |
Inhibitory effects of hydroxysafflor yellow A on the formation of advanced glycation end products in vitro.
Topics: Chalcone; Glucose; Glycation End Products, Advanced; Lysine; Peptides; Pyruvaldehyde; Quinones; Ribose; Serum Albumin, Bovine | 2012 |
Maternal plasma advanced glycation end products concentrations in response to oral 50-gram glucose load in mid-pregnancy: a pilot study.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Female; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Mass Spectrometry; Pilot Projects; Pregnancy; Pregnancy Trimester, Second; Prospective Studies; Pyruvaldehyde | 2012 |
Gentamicin caused renal injury deeply related to methylglyoxal and N(ɛ)-(carboxyethyl)lysine (CEL).
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Gentamicins; Glutathione; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Lysine; Male; Metformin; Pyruvaldehyde; Rats; Rats, Wistar | 2013 |
Increased circulating advanced glycation endproducts (AGEs) in acute trauma patients.
Topics: Acute Disease; Adult; Female; Glycation End Products, Advanced; Humans; Intensive Care Units; Kinetics; Longitudinal Studies; Lysine; Male; Middle Aged; Pyruvaldehyde; Severity of Illness Index; Wounds and Injuries | 2014 |
Oxidative damage of DNA induced by the reaction of methylglyoxal with lysine in the presence of ferritin.
Topics: Deferoxamine; DNA; DNA Breaks, Double-Stranded; DNA Cleavage; Ferritins; Free Radical Scavengers; Lysine; Plasmids; Pyruvaldehyde; Reactive Oxygen Species | 2013 |
Interaction of S-nitrosoglutathione with methemoglobin under conditions of modeling carbonyl stress.
Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Hemoglobins; Hydrogen Peroxide; Kinetics; Lysine; Maillard Reaction; Methemoglobin; Models, Chemical; Oxidation-Reduction; Oxygen; Protein Carbonylation; Pyruvaldehyde; S-Nitrosoglutathione | 2013 |
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Nerve Fibers; Pyruvaldehyde; Sensory Thresholds; Young Adult | 2013 |
Potential of birds to serve as pathology-free models of type 2 diabetes, part 2: do high levels of carbonyl-scavenging amino acids (e.g., taurine) and low concentrations of methylglyoxal limit the production of advanced glycation end-products?
Topics: Albumins; Animals; Arginine; Birds; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Pyruvaldehyde; Taurine | 2014 |
Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts.
Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Collagen; Dimerization; Glycation End Products, Advanced; Glyoxal; Lysine; Pyruvaldehyde; Trypsin | 2014 |
Characterization of the deoxyguanosine-lysine cross-link of methylglyoxal.
Topics: Cross-Linking Reagents; Deoxyguanosine; Lysine; Molecular Structure; Pyruvaldehyde; Stereoisomerism | 2014 |
Increased renal semicarbazide-sensitive amine oxidase activity and methylglyoxal levels in aristolochic acid-induced nephrotoxicity.
Topics: Amine Oxidase (Copper-Containing); Animals; Aristolochic Acids; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Lysine; Male; Metformin; Mice; Mice, Inbred C57BL; Pyruvaldehyde | 2014 |
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Glucose; Glycolates; Glyoxal; Humans; Intracellular Signaling Peptides and Proteins; Lactates; Lysine; Mass Spectrometry; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Protein Deglycase DJ-1; Pyruvaldehyde | 2015 |
Influence of nonenzymatic posttranslational modifications on constitution, oligomerization and receptor binding of S100A12.
Topics: Amination; Animals; Arginine; Humans; Imidazoles; Kinetics; Lysine; Mice; Protein Binding; Protein Conformation; Protein Multimerization; Protein Processing, Post-Translational; Pyrimidines; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; S100 Proteins; S100A12 Protein; Solutions | 2014 |
The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal.
Topics: Arginine; Cysteine; Escherichia coli Proteins; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glyoxal; Lysine; Molecular Chaperones; Pyruvaldehyde; Schiff Bases | 2015 |
Methylglyoxal and carboxyethyllysine reduce glutamate uptake and S100B secretion in the hippocampus independently of RAGE activation.
Topics: Animals; Astrocytes; Biological Transport; Diabetes Mellitus; Energy Metabolism; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Hyperglycemia; Lysine; Male; Oxidation-Reduction; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; S100 Calcium Binding Protein beta Subunit | 2016 |
Structural changes in histone H2A by methylglyoxal generate highly immunogenic amorphous aggregates with implications in auto-immune response in cancer.
Topics: Adolescent; Adult; Animals; Antibodies, Neoplasm; Autoantibodies; Case-Control Studies; Epitopes; Female; Gastrointestinal Neoplasms; Histones; Humans; Lung Neoplasms; Lysine; Male; Middle Aged; Prostatic Neoplasms; Pyruvaldehyde; Rabbits | 2016 |
Neo-epitopes on methylglyoxal modified human serum albumin lead to aggressive autoimmune response in diabetes.
Topics: Autoimmunity; Case-Control Studies; Diabetes Mellitus, Type 2; Epitopes; Female; Humans; Hydrophobic and Hydrophilic Interactions; Immunoglobulin G; Lysine; Male; Protein Conformation; Pyruvaldehyde; Serum Albumin | 2016 |
Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells.
Topics: Catechin; Catechols; Cell Line; Epithelial Cells; Fatty Alcohols; Glutathione; Glycation End Products, Advanced; Heme Oxygenase-1; Humans; Lysine; Malus; NF-E2-Related Factor 2; Phloretin; Phytochemicals; Protective Agents; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Retinal Pigment Epithelium; Tea; Zingiber officinale | 2016 |
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde | 2016 |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dinoprost; Embryo, Mammalian; Embryonic Development; Female; Fetal Development; Fetal Resorption; Gene Expression; Liver; Lysine; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Pregnancy; Pregnancy in Diabetics; Pyruvaldehyde; Receptor for Advanced Glycation End Products | 2016 |
A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).
Topics: Adiponectin; Adult; Agaricus; Antioxidants; beta-Glucans; Biomarkers; Body Mass Index; Chitin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dinoprost; Ergothioneine; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Insulin Resistance; Leptin; Linear Models; Lysine; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Oxidative Stress; Polyphenols; Pyruvaldehyde; Retrospective Studies; Risk Factors; Triglycerides; Vitamin D | 2016 |
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum | 2017 |
Effect of rosmarinic acid and carnosic acid on AGEs formation in vitro.
Topics: Abietanes; Animals; Cattle; Cinnamates; Depsides; Glucose; Glycation End Products, Advanced; Glyoxal; Lysine; Protein Carbonylation; Pyruvaldehyde; Rosmarinic Acid; Serum Albumin, Bovine | 2017 |
Inhibitory effect of sugarcane molasses extract on the formation of N
Topics: Antioxidants; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Molasses; Pyruvaldehyde; Saccharum | 2017 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Influence of Quercetin and Its Methylglyoxal Adducts on the Formation of α-Dicarbonyl Compounds in a Lysine/Glucose Model System.
Topics: Glucose; Glyoxal; Hot Temperature; Lysine; Maillard Reaction; Molecular Structure; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry | 2017 |
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry | 2017 |
Inhibition of Methylglyoxal-Induced Histone H1 N
Topics: Catechin; Glycation End Products, Advanced; Histones; Hydrogen Peroxide; Lysine; Pyruvaldehyde; Schiff Bases | 2018 |
Modification of chickpea cystatin by reactive dicarbonyl species: Glycation, oxidation and aggregation.
Topics: Arginine; Cicer; Cystatins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Oxidation-Reduction; Plant Proteins; Protein Aggregates; Pyruvaldehyde | 2018 |
Investigating the Glycating Effects of Glucose, Glyoxal and Methylglyoxal on Human Sperm.
Topics: DNA Damage; Fertility; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Male; Pyruvaldehyde; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa | 2018 |
Effects of glycation on human γd-crystallin proteins by different glycation-inducing agents.
Topics: Cataract; Diabetes Complications; Fructosamine; Galactose; gamma-Crystallins; Glycation End Products, Advanced; Glycosylation; Humans; Lens, Crystalline; Lysine; Protein Aggregation, Pathological; Protein Denaturation; Pyruvaldehyde; Ribose | 2018 |
Advanced Glycation End Products and esRAGE Are Associated With Bone Turnover and Incidence of Hip Fracture in Older Men.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Bone Density; Bone Remodeling; Diabetes Mellitus; Follow-Up Studies; Glycation End Products, Advanced; Hip Fractures; Humans; Incidence; Lysine; Male; Predictive Value of Tests; Prognosis; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Risk Factors | 2018 |
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.
Topics: Actins; Adult; Animals; Arginine; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glycolysis; Heart Failure; Heart Ventricles; Humans; Lysine; Male; Mice; Middle Aged; Myosins; Pyruvaldehyde; Sarcomeres; Single-Cell Analysis | 2018 |
Methylglyoxal as a prognostic factor in patients with chronic kidney disease.
Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Deoxyglucose; Diabetic Nephropathies; Disease Progression; Female; Humans; Japan; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvaldehyde; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Up-Regulation | 2019 |
Effect of Roasting and Storage on the Formation of Maillard Reaction and Sugar Degradation Products in Hazelnuts ( Corylus avellana L.).
Topics: Cooking; Corylus; Food Storage; Furaldehyde; Hot Temperature; Lysine; Maillard Reaction; Nuts; Pyruvaldehyde; Sugars | 2019 |
Effects of Catechins on N
Topics: Camellia sinensis; Catechin; Food Handling; Lysine; Models, Chemical; Molecular Structure; Plant Leaves; Pyruvaldehyde; Tea | 2019 |
Microplate-based Assay for Screening of Advanced Glycation End Products Binding to Its Receptor.
Topics: Antibodies, Immobilized; Biosensing Techniques; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Lab-On-A-Chip Devices; Lysine; Protein Binding; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine | 2019 |
Structural modification and digestibility change of β-lactoglobulin modified by methylglyoxal with the simulated reheating of dairy products.
Topics: Chromatography, High Pressure Liquid; Dairy Products; Electrophoresis, Polyacrylamide Gel; Lactoglobulins; Lysine; Pepsin A; Pyruvaldehyde; Tandem Mass Spectrometry; Temperature | 2019 |
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry | 2019 |
Formation of α-Dicarbonyls from Dairy Related Carbohydrates with and without Nα-Acetyl-l-Lysine during Incubation at 40 and 50 °C.
Topics: Animals; Cattle; Dairy Products; Galactose; Glucose; Glyoxal; Hot Temperature; Lactose; Lysine; Maillard Reaction; Milk; Oligosaccharides; Oxidation-Reduction; Pyruvaldehyde | 2019 |
Formation of N
Topics: Camellia sinensis; Catechin; Food Analysis; Food Handling; Gallic Acid; Glyoxal; Lysine; Plant Leaves; Polyphenols; Pyruvaldehyde; Tea | 2019 |
Physico-chemical Changes Induced in the Serum Proteins Immunoglobulin G and Fibrinogen Mediated by Methylglyoxal.
Topics: Arginine; Benzothiazoles; Fibrinogen; Furaldehyde; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Kinetics; Lysine; Malondialdehyde; Oxidation-Reduction; Protein Carbonylation; Pyruvaldehyde; Solutions; Spectrometry, Fluorescence | 2020 |
Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes.
Topics: Alkynes; Glutathione; Glycolysis; Glycosylation; HEK293 Cells; Humans; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Recombinant Proteins; Thiolester Hydrolases | 2020 |
Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation.
Topics: Diabetes Mellitus, Type 1; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Imidazoles; Immunoassay; Ketoses; Lysine; Peptides; Protein Processing, Post-Translational; Pyruvaldehyde | 2019 |
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature | 2020 |
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde | 2020 |
In vitro evaluation of anti-methylglyoxal/glyoxal activity of three phytosterols using glycated bovine serum albumin models.
Topics: Animals; Cattle; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Lysine; Phytosterols; Pyruvaldehyde; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Compounds | 2020 |
Gastrointestinal digestion of dietary advanced glycation endproducts using an in vitro model of the gastrointestinal tract (TIM-1).
Topics: Animals; Arginine; Chromatography, Liquid; Digestion; Fruit and Vegetable Juices; Gastrointestinal Tract; Glycation End Products, Advanced; Glyoxal; Hepatitis A Virus Cellular Receptor 1; Humans; Lysine; Milk; Pyruvaldehyde; Tandem Mass Spectrometry; Zingiber officinale | 2020 |
Simultaneous generation of acrylamide, β-carboline heterocyclic amines and advanced glycation ends products in an aqueous Maillard reaction model system.
Topics: Acrylamide; Amines; Asparagine; Carbolines; Chromatography, Gas; Chromatography, High Pressure Liquid; Glucose; Glycation End Products, Advanced; Harmine; Hot Temperature; Lysine; Maillard Reaction; Models, Biological; Pyruvaldehyde | 2020 |
Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea.
Topics: Camellia sinensis; Chromatography, High Pressure Liquid; Desiccation; Food Handling; Glycation End Products, Advanced; Humans; Imidazoles; Isomerism; Lysine; Plant Extracts; Plant Leaves; Pyruvaldehyde; Tandem Mass Spectrometry; Tea | 2020 |
Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (Aβ): Insights into a mechanism of Alzheimer's disease (AD).
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arginine; Humans; Lysine; Mice; Peptide Fragments; Pyruvaldehyde; Superoxides | 2020 |
Methylglyoxal-Lysine Dimer, an Advanced Glycation End Product, Induces Inflammation via Interaction with RAGE in Mesangial Cells.
Topics: Animals; Cell Line; Glycation End Products, Advanced; Inflammation; Lysine; Mesangial Cells; Mice; Mitochondria; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Reactive Oxygen Species; Signal Transduction | 2021 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |
High-Resolution Mass Spectrometry Analysis of Melanoidins and Their Precursors Formed in a Model Study of the Maillard Reaction of Methylglyoxal with l-Alanine or l-Lysine.
Topics: Alanine; Lysine; Maillard Reaction; Mass Spectrometry; Polymers; Pyruvaldehyde | 2021 |
Biophysical and mass spectrometry based characterization of methylglyoxal-modified myoglobin: Role of advanced glycation end products in inducing protein structural alterations.
Topics: Glycation End Products, Advanced; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Myoglobin; Norleucine; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Pyrroles; Pyruvaldehyde | 2021 |
In Vitro and In Vivo Antiglycation Effects of Connarus ruber Extract.
Topics: Animals; Arginine; Collagen; Connaraceae; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guanidines; Lipids; Lysine; Pyruvaldehyde; Rats; Streptozocin | 2022 |
Age-related neuronal damage by advanced glycation end products through altered proteostasis.
Topics: Aging; Animals; Autophagy-Related Protein 5; bcl-2-Associated X Protein; Brain; Brain-Derived Neurotrophic Factor; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Lysine; Neurons; Proteostasis; Pyruvaldehyde; Rats; Rats, Wistar; Ubiquitin; Unfolded Protein Response | 2022 |
Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form
Topics: Esters; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Glyoxal; Hydrogen-Ion Concentration; Lysine; Magnesium Oxide; Phosphates; Pyruvaldehyde; Schiff Bases | 2022 |
Methylglyoxal and high glucose inhibit VEGFR2 phosphorylation at specific tyrosine residues.
Topics: Diabetes Mellitus; Endothelial Cells; Glucose; Humans; Lysine; Magnesium Oxide; Phosphorylation; Pyruvaldehyde; Tyrosine; Vascular Endothelial Growth Factor A | 2022 |
Maillard reaction products and amino acid cross-links in liquid infant formula: Effects of UHT treatment and storage.
Topics: Amino Acids; Glycation End Products, Advanced; Glyoxal; Humans; Infant Formula; Lysine; Lysinoalanine; Maillard Reaction; Pyruvaldehyde | 2022 |
On the Prediction of In Vitro Arginine Glycation of Short Peptides Using Artificial Neural Networks.
Topics: Arginine; Glycation End Products, Advanced; Lysine; Neural Networks, Computer; Peptides; Proteins; Pyruvaldehyde | 2022 |
Lipid Peroxidation Has Major Impact on Malondialdehyde-Derived but Only Minor Influence on Glyoxal and Methylglyoxal-Derived Protein Modifications in Carbohydrate-Rich Foods.
Topics: Carbohydrates; Glycation End Products, Advanced; Glyoxal; Lipid Peroxidation; Lysine; Malondialdehyde; Proteins; Pyruvaldehyde | 2022 |
Studies on the Reaction of Dietary Methylglyoxal and Creatine during Simulated Gastrointestinal Digestion and in Human Volunteers.
Topics: Arginine; Creatine; Digestion; Glycation End Products, Advanced; Healthy Volunteers; Humans; Lysine; Magnesium Oxide; Pyruvaldehyde; Tandem Mass Spectrometry | 2022 |
Disease Association of Anti‒Carboxyethyl Lysine Autoantibodies in Hidradenitis Suppurativa.
Topics: Autoantibodies; Hidradenitis Suppurativa; Humans; Immunoglobulin G; Lysine; Pyruvaldehyde; Quality of Life | 2023 |
Distinctive effects of different types of advanced glycation end-products (AGEs) on liver glucose metabolism.
Topics: Animals; Glucose; Glycation End Products, Advanced; Insulin Resistance; Liver; Lysine; Magnesium Oxide; Mice; Pyruvaldehyde | 2022 |
Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification.
Topics: Albumins; Arginine; Blood Proteins; Glycation End Products, Advanced; Humans; Lysine; Pyruvaldehyde; Transferrin | 2022 |
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle.
Topics: Aged; Animals; Ectopic Gene Expression; Glycation End Products, Advanced; Healthy Aging; Humans; Infant; Lysine; Maillard Reaction; Mice; Muscle, Skeletal; Proteins; Pyruvaldehyde; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Uncoupling Protein 1 | 2023 |
Inhibitory effect of Ginkgo biloba seeds peptides on methylglyoxal-induced glycations.
Topics: Arginine; Aspartic Acid; Ginkgo biloba; Glycation End Products, Advanced; Lysine; Maillard Reaction; Peptides; Proline; Pyruvaldehyde; Serum Albumin, Bovine; Valine | 2023 |
Glyoxal-derived advanced glycation end-products, N
Topics: Apoptosis; Gene Expression; Glycation End Products, Advanced; Glyoxal; Hepatocytes; Humans; Lysine; Maillard Reaction; Proteins; Pyruvaldehyde; Reactive Oxygen Species | 2023 |
Role of Nitric Oxide-Derived Metabolites in Reactions of Methylglyoxal with Lysine and Lysine-Rich Protein Leghemoglobin.
Topics: Carcinoma, Renal Cell; Free Radicals; Glycation End Products, Advanced; Hemoglobins; Humans; Kidney Neoplasms; Leghemoglobin; Lysine; Maillard Reaction; Nitric Oxide; Pyruvaldehyde | 2022 |
The Intake of Dicarbonyls and Advanced Glycation Endproducts as Part of the Habitual Diet Is Not Associated with Intestinal Inflammation in Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients.
Topics: Diet; Glycation End Products, Advanced; Humans; Inflammation; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Lysine; Pyruvaldehyde | 2022 |
Quantitation of α-Dicarbonyls, Lysine- and Arginine-Derived Advanced Glycation End Products, in Commercial Canned Meat and Seafood Products.
Topics: Arginine; Glycation End Products, Advanced; Glyoxal; Lysine; Meat; Pyruvaldehyde; Seafood | 2023 |
Application of tea polyphenols as additives in brown fermented milk: Potential analysis of mitigating Maillard reaction products.
Topics: Animals; Glycation End Products, Advanced; Glyoxal; Lysine; Magnesium Oxide; Maillard Reaction; Milk; Polyphenols; Pyruvaldehyde; Tea | 2023 |
Study on the non-enzymatic browning of lotus rhizome juice during sterilization mediated by 1,2-dicarboxyl and heterocyclic compounds.
Topics: Asparagine; Fructose; Glucose; Glutamine; Glyoxal; Heterocyclic Compounds; Lotus; Lysine; Maillard Reaction; Pyruvaldehyde; Rhizome; Sterilization | 2024 |
Investigation on the simultaneous inhibition of advanced glycation end products, 4-methylimidazole and hydroxymethylfurfural in thermal reaction meat flavorings by liquiritigenin, liquiritin and glycyrrhizic acid and possible pathways.
Topics: Animals; Cattle; Free Radicals; Glycation End Products, Advanced; Glycyrrhizic Acid; Lysine; Meat; Pyruvaldehyde; Tandem Mass Spectrometry | 2023 |