Compounds > pyruvaldehyde

pyruvaldehyde and imidazolone

pyruvaldehyde has been researched along with imidazolone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's7 (24.14)29.6817
2010's16 (55.17)24.3611
2020's5 (17.24)2.80

Authors

AuthorsStudies
Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S1
Berg, TJ; Birkeland, KI; Brownlee, M; Giardino, I; Hanssen, KF; Kilhovd, BK; Thornalley, PJ; Torjesen, PA1
Ahmed, N; Dawczynski, J; Franke, S; Haik, GM; Stein, G; Strobel, J; Thornalley, PJ1
Bourajjaj, M; Schalkwijk, CG; Stehouwer, CD; van Hinsbergh, VW1
Thornalley, PJ1
Gao, Y; Wang, Y1
Agardh, CD; Agardh, E; Berg, JP; Fosmark, DS; Hanssen, KF; Jensen, AB; Sandvik, L1
Hanssen, KF; Juutilainen, A; Kilhovd, BK; Laakso, M; Lehto, S; Rönnemaa, T; Torjesen, PA1
Berg, JP; Hanssen, KF; Jensen, AB; Kilhovd, B; Lund, T; Pepaj, M; Svindland, A1
Biswas, A; Nagaraj, RH; Panda, AK; Pasupuleti, N; Santhoshkumar, P; Shanthakumar, S; Wang, B1
Field, MJ; Moosavi-Movahedi, AA; Nasiri, R; Zahedi, M1
Kartika, R; Spiegel, DA; Wang, T1
Beisswenger, PJ; Howell, SK; Mauer, M; Miller, ME; Rich, SS; Russell, GB1
Dahl-Jørgensen, K; Fagerland, MW; Hanssen, KF; Jørum, E; Karimé, B; Mellgren, SI; Monnier, VM; Sveen, KA1
Cleary, P; Gao, X; Genuth, S; Lachin, J; Monnier, VM; Sell, DR; Sun, W1
Augner, K; Eichler, J; Pischetsrieder, M; Utz, W1
Beisswenger, PJ; Howell, S; Knowler, WC; Lemley, KV; Mauer, M; Nelson, RG; Saulnier, PJ; Tanamas, SK; Weil, EJ; Wheelock, KM; Yee, B1
Yaylayan, VA; Zhu, Y1
Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC1
Higashimoto, Y; Ishibashi, Y; Matsui, T; Nakamura, N; Sotokawauchi, A; Yamagishi, SI1
Bekki, M; Fukumoto, Y; Honda, A; Igata, S; Kojima, R; Maeda, S; Matsui, T; Nakamura, T; Sugiyama, Y; Sun, J; Tahara, A; Tahara, N; Yamagishi, SI; Yoshida, R1
Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S1
Antonova, K; Bankin, M; Frolov, A; Gensberger-Reigl, S; Heymich, ML; Leonova, T; Lukasheva, E; Medvedev, S; Mehmood, T; Pischetsrieder, M; Smolikova, G; Soboleva, A; Vikhnina, M1
Carganico, S; Gallo, A; Lapolla, A; Nuti, F; Papini, AM; Piarulli, F; Real-Fernandez, F; Rentier, C; Rossi, G; Rovero, P; Traldi, P1
Ye, Y; Zhang, B; Zhang, W; Zhu, H1
Dave, J; Fraser, S; Guir, ALS; McEwen, JM; Scheck, RA1
Lee, KW; Lim, JM; Yoo, HJ1
Bose, N; Chamoli, M; Chaudhuri, J; Farrera, DO; Galligan, JJ; Guha, S; Hodge, B; Kapahi, P; Lithgow, G; Muthaiyan Shanmugam, M; Roberts, C; Sahu, AK; Sarpong, R; Sellegounder, D1
Antognelli, C; Bozza, S; Costantini, C; Graziani, A; Manfredelli, D; Pariano, M; Puccetti, P; Romani, L; Talesa, VN1

Reviews

1 review(s) available for pyruvaldehyde and imidazolone

ArticleYear
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus.
    Biochemical Society transactions, 2003, Volume: 31, Issue:Pt 6

    Topics: Diabetic Angiopathies; Humans; Imidazoles; Pyruvaldehyde

2003

Trials

2 trial(s) available for pyruvaldehyde and imidazolone

ArticleYear
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:12

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Imidazoles; Indians, North American; Kidney; Kidney Glomerulus; Losartan; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pyruvaldehyde

2016
Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine.
    Rejuvenation research, 2019, Volume: 22, Issue:5

    Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Imidazoles; Inflammation; Male; Middle Aged; Protein Binding; Pyruvaldehyde; Vascular Stiffness

2019

Other Studies

26 other study(ies) available for pyruvaldehyde and imidazolone

ArticleYear
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia

1998
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:2

    Topics: Diabetes Mellitus, Type 2; Humans; Imidazoles; Immunoassay; Lysine; Pyruvaldehyde; Sensitivity and Specificity

2003
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:12

    Topics: Aged; Arginine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Female; Fluorometry; Glycation End Products, Advanced; Humans; Hydrolysis; Imidazoles; Lens, Crystalline; Lysine; Male; Mass Spectrometry; Middle Aged; Pyruvaldehyde

2003
Dicarbonyl intermediates in the maillard reaction.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Animals; Carbon; Glycation End Products, Advanced; Humans; Imidazoles; Kinetics; Lipid Peroxidation; Maillard Reaction; Organ Specificity; Pyruvaldehyde; Rats

2005
Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal.
    Biochemistry, 2006, Dec-26, Volume: 45, Issue:51

    Topics: Amino Acid Sequence; Arginine; Chromatography, Liquid; Hemoglobins; Humans; Imidazoles; Molecular Sequence Data; Protein Subunits; Pyruvaldehyde; Surface Properties; Tandem Mass Spectrometry

2006
Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone.
    Acta ophthalmologica, 2009, Volume: 87, Issue:5

    Topics: Adolescent; Adult; Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Fundus Oculi; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Immunoassay; Male; Middle Aged; Prevalence; Pyruvaldehyde; Young Adult

2009
Increased serum levels of methylglyoxal-derived hydroimidazolone-AGE are associated with increased cardiovascular disease mortality in nondiabetic women.
    Atherosclerosis, 2009, Volume: 205, Issue:2

    Topics: Cardiovascular Diseases; Case-Control Studies; Cohort Studies; Diabetes Mellitus, Type 2; Female; Finland; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Male; Middle Aged; Odds Ratio; Pyruvaldehyde; Regression Analysis; Sex Factors

2009
Fibrin(ogen) may be an important target for methylglyoxal-derived AGE modification in elastic arteries of humans.
    Diabetes & vascular disease research, 2011, Volume: 8, Issue:4

    Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Aorta; Blotting, Western; Carotid Artery, Common; Case-Control Studies; Chromatography, Liquid; Diabetic Angiopathies; Elasticity; Female; Fibrin; Fibrinogen; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Male; Middle Aged; Molecular Sequence Data; Necrosis; Norway; Protein Processing, Post-Translational; Proteomics; Pyruvaldehyde; Tandem Mass Spectrometry

2011
Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amino Acid Sequence; Arginine; Binding Sites; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; HSP27 Heat-Shock Proteins; Imidazoles; Kinetics; Molecular Chaperones; Molecular Sequence Data; Molecular Structure; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvaldehyde; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Thermodynamics

2012
Comparative DFT study to determine if α-oxoaldehydes are precursors for pentosidine formation.
    The journal of physical chemistry. A, 2012, Mar-22, Volume: 116, Issue:11

    Topics: Arginine; Glycosylation; Glyoxal; Imidazoles; Kinetics; Lysine; Molecular Structure; Pyruvaldehyde; Quantum Theory; Schiff Bases; Thermodynamics; Water

2012
Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones.
    Journal of the American Chemical Society, 2012, May-30, Volume: 134, Issue:21

    Topics: Amino Acid Sequence; Arginine; Imidazoles; Isomerism; Oligopeptides; Protein Processing, Post-Translational; Pyruvaldehyde

2012
Early progression of diabetic nephropathy correlates with methylglyoxal-derived advanced glycation end products.
    Diabetes care, 2013, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Child; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Imidazoles; Male; Pyruvaldehyde; Young Adult

2013
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study.
    Diabetes care, 2013, Volume: 36, Issue:11

    Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Nerve Fibers; Pyruvaldehyde; Sensory Thresholds; Young Adult

2013
Skin advanced glycation end products glucosepane and methylglyoxal hydroimidazolone are independently associated with long-term microvascular complication progression of type 1 diabetes.
    Diabetes, 2015, Volume: 64, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Female; Glycation End Products, Advanced; Humans; Imidazoles; Logistic Models; Male; Microvessels; Multivariate Analysis; Pyruvaldehyde; Skin; Young Adult

2015
Influence of nonenzymatic posttranslational modifications on constitution, oligomerization and receptor binding of S100A12.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Amination; Animals; Arginine; Humans; Imidazoles; Kinetics; Lysine; Mice; Protein Binding; Protein Conformation; Protein Multimerization; Protein Processing, Post-Translational; Pyrimidines; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; S100 Proteins; S100A12 Protein; Solutions

2014
Interaction of free arginine and guanidine with glucose under thermal processing conditions and formation of Amadori-derived imidazolones.
    Food chemistry, 2017, Apr-01, Volume: 220

    Topics: Arginine; Glucose; Guanidine; Imidazoles; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
    Diabetes care, 2017, Volume: 40, Issue:4

    Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides

2017
Methylglyoxal-derived hydroimidazolone-1 evokes inflammatory reactions in endothelial cells via an interaction with receptor for advanced glycation end products.
    Diabetes & vascular disease research, 2017, Volume: 14, Issue:5

    Topics: Cell Adhesion; Cell Line; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Inflammation Mediators; Leukocytes; Protein Binding; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Signal Transduction; Time Factors

2017
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
    Journal of agricultural and food chemistry, 2019, May-22, Volume: 67, Issue:20

    Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry

2019
Analysis of Chemically Labile Glycation Adducts in Seed Proteins: Case Study of Methylglyoxal-Derived Hydroimidazolone 1 (MG-H1).
    International journal of molecular sciences, 2019, Jul-26, Volume: 20, Issue:15

    Topics: Chromatography, Liquid; Glycation End Products, Advanced; Glycosylation; Hydrolysis; Imidazoles; Mass Spectrometry; Plant Proteins; Pyruvaldehyde; Reproducibility of Results; Seeds; Solid Phase Extraction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2019
Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation.
    Folia biologica, 2019, Volume: 65, Issue:4

    Topics: Diabetes Mellitus, Type 1; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Imidazoles; Immunoassay; Ketoses; Lysine; Peptides; Protein Processing, Post-Translational; Pyruvaldehyde

2019
Methylglyoxal-hydroimidazolones (MG-Hs) instead of Nɛ-(carboxymethyl)-l-lysine (CML) is the major advanced glycation end-product during drying process in black tea.
    Food chemistry, 2020, Dec-15, Volume: 333

    Topics: Camellia sinensis; Chromatography, High Pressure Liquid; Desiccation; Food Handling; Glycation End Products, Advanced; Humans; Imidazoles; Isomerism; Lysine; Plant Extracts; Plant Leaves; Pyruvaldehyde; Tandem Mass Spectrometry; Tea

2020
Synergistic sequence contributions bias glycation outcomes.
    Nature communications, 2021, 06-03, Volume: 12, Issue:1

    Topics: Amino Acid Sequence; Arginine; Glycation End Products, Advanced; Glycosylation; HEK293 Cells; Humans; Imidazoles; Isomerism; Peptide Library; Protein Processing, Post-Translational; Proteins; Pyruvaldehyde

2021
High Molecular Weight Fucoidan Restores Intestinal Integrity by Regulating Inflammation and Tight Junction Loss Induced by Methylglyoxal-Derived Hydroimidazolone-1.
    Marine drugs, 2022, Sep-17, Volume: 20, Issue:9

    Topics: Animals; Caco-2 Cells; Claudin-1; Fluoresceins; Humans; Imidazoles; Inflammation; Intestinal Mucosa; Isothiocyanates; Mice; Mice, Inbred ICR; Molecular Weight; NF-kappa B; Occludin; Permeability; Polysaccharides; Pyruvaldehyde; Reactive Oxygen Species; RNA, Messenger; Tight Junctions

2022
Methylglyoxal-derived hydroimidazolone, MG-H1, increases food intake by altering tyramine signaling via the GATA transcription factor ELT-3 in
    eLife, 2023, 09-20, Volume: 12

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Eating; GATA Transcription Factors; Glycation End Products, Advanced; Magnesium Oxide; Pyruvaldehyde; Signal Transduction; Tyramine

2023
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein S1 Induces Methylglyoxal-Derived Hydroimidazolone/Receptor for Advanced Glycation End Products (MG-H1/RAGE) Activation to Promote Inflammation in Human Bronchial BEAS-2B Cells.
    International journal of molecular sciences, 2023, Oct-03, Volume: 24, Issue:19

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; Glycation End Products, Advanced; Humans; Inflammation; Pyruvaldehyde; Receptor for Advanced Glycation End Products; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2023