pyruvaldehyde and deoxyguanosine

pyruvaldehyde has been researched along with deoxyguanosine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (20.00)18.2507
2000's10 (50.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishida, H; Iwami, T; Kosuge, T; Nagao, M; Nukaya, H; Sugimura, T; Suwa, Y; Tsuji, K; Wakabayashi, K1
Fang, JL; Hou, SM; Nori, P; Vaca, CE1
Nukaya, H; Sugimura, T; Tada, A; Totsuka, Y; Tsuji, K; Wakabayashi, K1
Casida, JE; Quistad, GB; Schneider, M1
Kamiya, H; Murata-Kamiya, N1
Akisik, EE; Anak, SS; Beneduce, G; Calzone, R; d'Ischia, M; De Nicola, E; Degan, P; Dunster, C; Kelly, FJ; Lloret, A; Manini, P; Nobili, B; Pagano, G; Pallardó, FV; Saviano, A; Vuttariello, E; Warnau, M; Zatterale, A1
Calzone, R; Castello, G; d'Ischia, M; Degan, P; Dunster, C; Giudice, A; Kelly, FJ; Kilinç, Y; Lloret, A; Manini, P; Masella, R; Pagano, G; Pallardó, FV; Vuttariello, E; Warnau, M; Zatterale, A1
Hachisuka, K; Kasai, H; Kawai, K; Maekawa, M; Nakamura, H; Sawa, R; Takahashi, Y; Watanabe, T1
Angerer, J; Bidmon, C; Frischmann, M; Pischetsrieder, M1
Brusco, A; Calzone, R; Cavalieri, S; d'Ischia, M; Degan, P; Kavakli, K; Lloret, A; Manini, P; Pagano, G; Pallardó, FV; Pisanti, MA; Vuttariello, E; Zatterale, A1
Hamada, Y; Hazaka, Y; Ichijo, H; Kani, S; Minami, Y; Nakayama, E; Onishi, N; Sougawa, N; Takeda, K; Umeda, T; Yoda, A1
Calzone, R; d'Ischia, M; Degan, P; Dunster, C; Kelly, FJ; Lloret, A; Manini, P; Pagano, G; Pallardó, FV; Zatterale, A1
Fleming, T; Rabbani, N; Thornalley, PJ1
Cao, H; Hong, H; Jiang, Y; Wang, Y; Yuan, B1
Kim, CS; Kim, J; Kim, JS; Kim, NH; Sohn, E1
Kim, CS; Kim, J; Kim, JS; Sohn, E1
Jung, DH; Kim, JS; Kim, KM; Kim, YS; Lee, J1
Ahmad, S; Alam, K; Ali, A; Habib, S; Salman Khan, M; Shahab, U1
Millsap, AD; Petrova, KV; Rizzo, CJ; Stec, DF1
Shuck, SC; Termini, JS; Wuenschell, GE1

Reviews

1 review(s) available for pyruvaldehyde and deoxyguanosine

ArticleYear
Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases.
    Free radical biology & medicine, 2008, Feb-15, Volume: 44, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Aged; Ataxia Telangiectasia; Bloom Syndrome; Child; Deoxyguanosine; DNA Damage; Down Syndrome; Fanconi Anemia; Female; Glutathione; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Werner Syndrome; Xeroderma Pigmentosum

2008

Other Studies

19 other study(ies) available for pyruvaldehyde and deoxyguanosine

ArticleYear
N-2 acetylation of 2'-deoxyguanosine by coffee mutagens, methylglyoxal and hydrogen peroxide.
    Mutation research, 1990, Volume: 245, Issue:4

    Topics: Acetylation; Chromatography, High Pressure Liquid; Coffee; Deoxyguanosine; Hydrogen Peroxide; Molecular Structure; Mutagenicity Tests; Mutagens; Pyruvaldehyde; Salmonella typhimurium; Time Factors

1990
Methylglyoxal induces hprt mutation and DNA adducts in human T-lymphocytes in vitro.
    Environmental and molecular mutagenesis, 1995, Volume: 26, Issue:4

    Topics: Adult; Aged; Cell Division; Cell Survival; Cells, Cultured; Clone Cells; Deoxyguanosine; DNA Adducts; Humans; Hypoxanthine Phosphoribosyltransferase; Imidazoles; Kinetics; Male; Middle Aged; Mutagenesis; Mutagenicity Tests; Mutagens; Pyruvaldehyde; T-Lymphocytes; Time Factors

1995
32P-Postlabeling analysis of a DNA adduct, an N2-acetyl derivative of guanine, formed in vitro by methylglyoxal and hydrogen peroxide in combination.
    Mutation research, 1996, Apr-13, Volume: 351, Issue:2

    Topics: Acetylation; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Hydrogen Peroxide; Mutagens; Pyruvaldehyde

1996
N2,7-bis(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine: identical noncyclic adducts with 1,3-dichloropropene epoxides and methylglyoxal.
    Chemical research in toxicology, 1998, Volume: 11, Issue:12

    Topics: Allyl Compounds; Catalysis; Chromatography, High Pressure Liquid; Deoxyguanosine; Hydrocarbons, Chlorinated; Insecticides; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Pyruvaldehyde; Spectrophotometry, Ultraviolet

1998
Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.
    Nucleic acids research, 2001, Aug-15, Volume: 29, Issue:16

    Topics: Acetylcysteine; Base Sequence; Binding Sites; Cross-Linking Reagents; Deoxyguanosine; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Guanine; Hydrogen-Ion Concentration; Kinetics; Lysine; Pyruvaldehyde; Reducing Agents; Substrate Specificity; Templates, Genetic

2001
Gender- and age-related distinctions for the in vivo prooxidant state in Fanconi anaemia patients.
    Carcinogenesis, 2004, Volume: 25, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Age Factors; Ascorbic Acid; Case-Control Studies; Child; Child, Preschool; Chromosome Breakage; Chromosomes, Human; Deoxyguanosine; DNA; Fanconi Anemia; Female; Glutathione; Glutathione Disulfide; Heterozygote; Humans; Infant; Leukocytes; Male; Oxidation-Reduction; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Respiratory Burst; Sex Factors; Transplants; Uric Acid; Vitamin E

2004
In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes.
    Free radical research, 2005, Volume: 39, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Antioxidants; Chromatography, High Pressure Liquid; Deoxyguanosine; Dinoprost; Female; Glutathione; Glyoxal; Heterozygote; Humans; Leukocytes; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Werner Syndrome

2005
Identification of 4-oxo-2-hexenal and other direct mutagens formed in model lipid peroxidation reactions as dGuo adducts.
    Chemical research in toxicology, 2006, Volume: 19, Issue:1

    Topics: Aldehydes; Deoxyguanosine; Glyoxylates; Hemin; Linoleic Acids; Linolenic Acids; Lipid Peroxidation; Models, Biological; Mutagenicity Tests; Mutagens; Plant Oils; Pyruvaldehyde; Salmonella

2006
Identification of DNA adducts of methylglyoxal.
    Chemical research in toxicology, 2005, Volume: 18, Issue:10

    Topics: Animals; Biomarkers; Chromatography, Liquid; Deoxyguanosine; DNA; DNA Adducts; Molecular Structure; Mutagens; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization

2005
Glutathione levels in blood from ataxia telangiectasia patients suggest in vivo adaptive mechanisms to oxidative stress.
    Clinical biochemistry, 2007, Volume: 40, Issue:9-10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adaptation, Physiological; Adolescent; Adult; Ataxia Telangiectasia; Child; Child, Preschool; Deoxyguanosine; DNA Damage; Female; Glutathione; Glyoxal; Humans; Male; Oxidative Stress; Pyruvaldehyde

2007
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.
    Genes to cells : devoted to molecular & cellular mechanisms, 2007, Volume: 12, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line; Checkpoint Kinase 1; Checkpoint Kinase 2; Deoxyguanosine; Diabetes Mellitus; Enzyme Activation; G2 Phase; Guanidines; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase Kinase 5; Mesangial Cells; Mitosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvaldehyde; RNA, Small Interfering; Signal Transduction

2007
Preparation of nucleotide advanced glycation endproducts--imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Deoxyguanosine; Glycation End Products, Advanced; Glyoxal; Imidazoles; Models, Molecular; Purines; Pyruvaldehyde

2008
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jun-24, Volume: 105, Issue:25

    Topics: Base Sequence; Deoxyguanosine; DNA Adducts; DNA Polymerase beta; DNA-Directed DNA Polymerase; Escherichia coli; Humans; Kinetics; Models, Biological; Molecular Sequence Data; Pyruvaldehyde; Tumor Cells, Cultured

2008
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Caspase 3; Cell Line; Deoxyguanosine; DNA Damage; Epithelial Cells; Glycation End Products, Advanced; Humans; Lens, Crystalline; Ornithine; Oxidative Stress; Pyridoxamine; Pyrimidines; Pyruvaldehyde

2010
Renal podocyte apoptosis in Zucker diabetic fatty rats: involvement of methylglyoxal-induced oxidative DNA damage.
    Journal of comparative pathology, 2011, Volume: 144, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA Damage; Hyperglycemia; In Situ Nick-End Labeling; Kidney; Male; Oxidative Stress; Podocytes; Pyruvaldehyde; Rats; Rats, Zucker

2011
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose.
    Experimental cell research, 2012, Jan-15, Volume: 318, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Apoptosis; Caspase 3; Cell Line; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus; Glycation End Products, Advanced; Hyperglycemia; Lactoylglutathione Lyase; Lipid Peroxidation; Mesangial Cells; Mice; Mitochondria; Ornithine; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pyrimidines; Pyruvaldehyde

2012
Glycoxidative damage to human DNA: Neo-antigenic epitopes on DNA molecule could be a possible reason for autoimmune response in type 1 diabetes.
    Glycobiology, 2014, Volume: 24, Issue:3

    Topics: Autoimmunity; Deoxyguanosine; Diabetes Mellitus, Type 1; DNA; DNA Damage; Epitopes; Glycation End Products, Advanced; Humans; Lymphocytes; Penicillamine; Pyridoxal; Pyruvaldehyde

2014
Characterization of the deoxyguanosine-lysine cross-link of methylglyoxal.
    Chemical research in toxicology, 2014, Jun-16, Volume: 27, Issue:6

    Topics: Cross-Linking Reagents; Deoxyguanosine; Lysine; Molecular Structure; Pyruvaldehyde; Stereoisomerism

2014
Product Studies and Mechanistic Analysis of the Reaction of Methylglyoxal with Deoxyguanosine.
    Chemical research in toxicology, 2018, 02-19, Volume: 31, Issue:2

    Topics: Deoxyguanosine; Molecular Structure; Pyruvaldehyde

2018