pyruvaldehyde has been researched along with deoxyglucose in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (17.33) | 18.2507 |
| 2000's | 19 (25.33) | 29.6817 |
| 2010's | 29 (38.67) | 24.3611 |
| 2020's | 14 (18.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, J; Hasuike, Y; Kawasaki, Y; Okado, A; Takahashi, M; Taniguchi, N; Teshima, T | 1 |
| Deck, LM; Gomez, MS; Gonzales, DM; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Vander Jagt, TJ | 1 |
| Asahi, M; Che, W; Higashiyama, S; Kaneto, H; Okado, A; Takahashi, M; Taniguchi, N | 1 |
| Hamaoka, R; Koh, YH; Mizuno, H; Suzuki, K; Taniguchi, N | 1 |
| Eriksson, UJ; Minhas, HS; Thornalley, PJ; Wentzel, P | 1 |
| Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD | 1 |
| Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E | 1 |
| Koh, YH; Suzuki, K; Taniguchi, N | 1 |
| Kikuchi, S; Makita, Z; Miyata, T; Moriwaka, F; Shinpo, K; Tashiro, K | 1 |
| Abordo, EA; Minhas, HS; Thornalley, PJ | 1 |
| Langborg, A; Minhas, HS; Thornalley, PJ | 1 |
| Kikuchi, S; Moriwaka, F; Ogata, A; Sasaki, H; Shinpo, K; Tashiro, K | 1 |
| Argirov, OK; Thornalley, PJ; Yurek-George, A | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A | 1 |
| Bierhaus, A; Häring, HU; Lehmann, R; Nawroth, PP; Schleicher, ED | 1 |
| Jahan, I; Ng, R; Thornalley, PJ | 1 |
| Beisswenger, PJ; Howell, SK; O'Dell, RM; Szwergold, BS; Touchette, AD; Wood, ME | 1 |
| Nakamoto, M; Nakayama, M; Numata, M; Sakai, A; Takesawa, S | 1 |
| Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M | 1 |
| Inagi, R; Kurokawa, K; Miyata, T; Nangaku, M; Ueda, Y; van Ypersele de Strihou, C; Yoshino, A | 1 |
| Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M | 1 |
| Akagawa, M; Sasaki, T; Suyama, K | 1 |
| Dohmae, N; Honke, K; Koh, YH; Miyamoto, Y; Park, YS; Suzuki, K; Takahashi, M; Takio, K; Taniguchi, N | 1 |
| Beisswenger, P; Ruggiero-Lopez, D | 1 |
| Asahi, M; Misonou, Y; Miyamoto, Y; Park, YS; Sakiyama, H; Takahashi, M; Taniguchi, N | 1 |
| Beisswenger, PJ; Drummond, KS; Howell, SK; Mauer, M; Nelson, RG; Szwergold, BS | 1 |
| Durand, I; Giudicelli, J; Murdaca, J; Pierron, A; Riboulet-Chavey, A; Van Obberghen, E | 1 |
| Shapira, A; Shazman, A; Shimoni, E; Ungar, Y | 1 |
| Chang, CD; Chang, DM; Chen, BG; Chern, CL; Huang, MH; Lee, CI; Lee, YJ; Liu, RH; Wang, HC; Wu, MY; Wu, TG | 1 |
| Artlett, CM; Kappler, F; Loughlin, DT; Sassi-Gaha, S; Schwartz, ML; Su, B; Tobia, AM | 1 |
| Higashi, T; Min, JZ; Toyo'oka, T; Yamamoto, M; Yu, HF | 1 |
| Arena, E; Ballistreri, G; Fallico, B; Tomaselli, F | 1 |
| Degen, J; Hellwig, M; Henle, T | 1 |
| Cavaillé, JP; Peiretti, F; Poggi, M; Stocker, P; Vidal, N | 1 |
| Schalkwijk, CG; Scheijen, JL | 1 |
| Kokkinidou, S; Peterson, DG | 1 |
| Artlett, CM; Loarca, L; Sassi-Gaha, S | 1 |
| Engelbrecht, B; Gawlowski, T; Mattern, Y; Scheibler, S; Stratmann, B; Tschoepe, D | 1 |
| Rabbani, N; Thornalley, PJ | 2 |
| Gazzani, G; Mascherpa, D; Papetti, A | 1 |
| Distler, L; Georgieva, A; Huppert, J; Kenkel, I; Pischetsrieder, M | 1 |
| Gökmen, V; Kocadağlı, T | 1 |
| Hanssen, NM; Maessen, DE; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM | 1 |
| Gökmen, V; Hamzalıoğlu, A | 2 |
| Dain, JA; Frost, L; Kirschenbaum, LJ; Liu, W; Ma, H; Seeram, NP | 1 |
| Andreozzi, F; Beguinot, F; Davalli, AM; Folli, F; Mannino, GC; Miele, C; Nigro, C; Procopio, T; Raciti, GA; Sesti, G | 1 |
| Morales, FJ; Navarro, M | 2 |
| Gökmen, V; Göncüoğlu Taş, N | 1 |
| Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC | 1 |
| Bergmans, DC; Schalkwijk, CG; van Bussel, BC; van de Poll, MC | 1 |
| Haluzik, M; Kazdova, L; Malinska, H; Markova, I; Škop, V; Svoboda, P; Trnovska, J | 1 |
| Nakaya, I; Nakayama, K; Nakayama, M; Soma, J; Tezuka, Y; Yahata, M | 1 |
| Gao, WY; Li, H; Liu, ZF; Ma, SB; Wang, XJ | 1 |
| Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S | 1 |
| Gao, WY; Li, H; Wang, XJ; Zhang, HX; Zhu, AH | 1 |
| Bianchi, M; Braghini, MR; D'Oria, V; Manco, M; Petrini, S | 1 |
| Alouffi, S; Khan, MWA | 1 |
| Ahmad, K; Choi, I; Lee, EJ; Lee, YH; Shaikh, S | 1 |
| Arena, E; Brighina, S; Fallico, B; Palmeri, R; Restuccia, C | 1 |
| Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y | 1 |
| Ahmad, S; Farooqui, A; Husain, A; Khanam, A; Rehman, S; Yusuf, MA | 1 |
| Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q | 1 |
| Auditore, A; Becker, AK; Fleming, T; Messlinger, K; Pischetsrieder, M; Reeh, PW; Sauer, SK | 1 |
| Chen, HD; Dain, JA; Gao, XH; Guo, H; Liu, C; Ma, H; Seeram, NP; Wan, Y | 1 |
| Akhter, A; Kausar, MA; Saeed, M; Siddiqui, AJ; Singh, R | 1 |
| Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ | 1 |
| Furuhashi, T; Odani, H; Ogawa, T; Tanaka, T; Yoshioka, S | 1 |
| Dagnelie, PC; Eussen, SJPM; Maasen, K; Opperhuizen, A; Schalkwijk, CG; Scheijen, JLJM; Stehouwer, CDA; van der Kallen, CJH; van Greevenbroek, MMJ | 1 |
| Grune, T; Herpich, C; Kochlik, B; Norman, K; Ott, C; Raupbach, J; Weber, D | 1 |
10 review(s) available for pyruvaldehyde and deoxyglucose
| Article | Year |
|---|---|
Chemistry and pathobiology of advanced glycation end products.
Topics: Aging; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Glycoproteins; Glycosylation; Glyoxal; Humans; Kidney Glomerulus; Lipid Peroxidation; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species | 2001 |
Metformin inhibition of glycation processes.
Topics: Azepines; Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Metformin; Pyruvaldehyde; Randomized Controlled Trials as Topic | 2003 |
A common pathway for intracellular reactive oxygen species production by glycoxidative and nitroxidative stress in vascular endothelial cells and smooth muscle cells.
Topics: Animals; Cells, Cultured; Deoxyglucose; Endothelium, Vascular; Humans; Muscle, Smooth; Oxidation-Reduction; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Signal Transduction; Umbilical Veins | 2005 |
Assay of methylglyoxal and glyoxal and control of peroxidase interference.
Topics: Animals; Deoxyglucose; Glyoxal; Humans; Models, Biological; Peroxidase; Pyruvaldehyde | 2014 |
Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease.
Topics: Aging; Aldehydes; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus; Glyoxal; Humans; Inflammation; Kidney Diseases; Models, Biological; Oxidative Stress; Pyruvaldehyde; Stress, Physiological | 2015 |
Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness.
Topics: Biomarkers; Comorbidity; Critical Care; Critical Illness; Deoxyglucose; Glyoxal; Humans; Hypoxia; Inflammation; Multiple Organ Failure; Pyruvaldehyde; Stress, Physiological | 2017 |
Dicarbonyls Generation, Toxicities, Detoxifications and Potential Roles in Diabetes Complications.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Consequences of Dicarbonyl Stress on Skeletal Muscle Proteins in Type 2 Diabetes.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Extracellular Matrix Proteins; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Muscle, Skeletal; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Glycation and Antioxidants: Hand in the Glove of Antiglycation and Natural Antioxidants.
Topics: Antigens, Neoplasm; Antioxidants; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lactoylglutathione Lyase; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappa B; Oxidative Stress; Plant Extracts; Polyphenols; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
The Role of Glyoxalase in Glycation and Carbonyl Stress Induced Metabolic Disorders.
Topics: Aging; Deoxyglucose; Diabetes Mellitus; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Isoenzymes; Lactoylglutathione Lyase; Metabolic Diseases; Neurodegenerative Diseases; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Schiff Bases; Signal Transduction | 2020 |
5 trial(s) available for pyruvaldehyde and deoxyglucose
| Article | Year |
|---|---|
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome | 1999 |
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors | 2000 |
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Cross-Over Studies; Deoxyglucose; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Administration Schedule; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Lispro; Middle Aged; Postprandial Period; Pyruvaldehyde; Regression Analysis | 2001 |
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde | 2003 |
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Glyoxal; Humans; Irbesartan; Male; Middle Aged; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors; Treatment Outcome | 2021 |
60 other study(ies) available for pyruvaldehyde and deoxyglucose
| Article | Year |
|---|---|
Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines.
Topics: Apoptosis; Cell Line; Cell Nucleus; Deoxyglucose; DNA, Neoplasm; Flow Cytometry; Glutathione; HL-60 Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Macrophages; Oxidants; Pyruvaldehyde; Tumor Cells, Cultured | 1996 |
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes.
Topics: Acrolein; Aldehydes; Amino Acids; Deoxyglucose; Enzyme Activation; Glutathione Reductase; Ketoses; Pyruvaldehyde; Spectrometry, Fluorescence | 1997 |
Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arteriosclerosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyglucose; Diabetic Angiopathies; Epidermal Growth Factor; Gene Expression; Guanidines; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Peroxides; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic | 1997 |
Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucosone.
Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Northern; Cell Survival; Deoxyglucose; Enzyme Activation; Flow Cytometry; Immunoblotting; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection | 1998 |
Teratogenicity of 3-deoxyglucosone and diabetic embryopathy.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glucose; Glyoxal; Hyperglycemia; Male; Pregnancy; Pyruvaldehyde; Rats; Teratogens | 1998 |
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia | 1998 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.
Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Leukocyte Common Antigens; Lysine; Male; Middle Aged; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyruvaldehyde; Risk Factors; T-Lymphocytes | 1999 |
The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells.
Topics: Aldehyde Reductase; Animals; Deoxyglucose; Flow Cytometry; Gene Expression; Glucose; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection | 1999 |
Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Synergism; Free Radical Scavengers; Glycation End Products, Advanced; Glycosylation; Neurodegenerative Diseases; Neurons; Oxidative Stress; Peroxides; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 1999 |
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidines; Hydrogen Peroxide; Macrophages; Mice; Necrosis; Nitroarginine; Oxidative Stress; Pyruvaldehyde | 1999 |
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin | 1999 |
Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Glutathione; Glycation End Products, Advanced; Guanidines; Motor Neurons; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Spinal Cord | 2000 |
Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.
Topics: Deoxyglucose; Enzyme Inhibitors; Glyoxal; Guanidines; Kinetics; Pyruvaldehyde; Spectrophotometry; Triazines | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses | 2001 |
Sodium sulfite and N-acetylcysteine: new additives to dialysate for inhibiting formation of glucose degradation products and advanced glycation end-products.
Topics: Acetylcysteine; Collagen Type IV; Deoxyglucose; Dialysis Solutions; Fluorescence; Glucose; Glycation End Products, Advanced; Glyoxylates; Humans; In Vitro Techniques; Pyruvaldehyde; Serum Albumin; Sulfites | 2001 |
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2002 |
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Guanidines; Humans; In Vitro Techniques; Kidney Failure, Chronic; Lactoylglutathione Lyase; Membranes, Artificial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde; Yeasts | 2002 |
Oxidative deamination of benzylamine by glycoxidation.
Topics: Benzaldehydes; Benzylamines; Chelating Agents; Copper; Deamination; Deoxyglucose; Edetic Acid; Free Radical Scavengers; Glucose; Glucose Oxidase; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Metals; Nitrogen; Oxidation-Reduction; Oxygen; Pyruvaldehyde; Reactive Oxygen Species | 2003 |
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyglucose; Erythrocytes; Glutathione; Glutathione Peroxidase; Glyoxal; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Muscle, Smooth; Oxidative Stress; Peptides; Phenylglyoxal; Protein Binding; Pyruvaldehyde; Rats; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2003 |
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
Topics: Adolescent; Adult; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Susceptibility; Glycated Hemoglobin; Humans; Indians, North American; Oxidative Stress; Pyruvaldehyde; Risk Factors | 2005 |
Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species.
Topics: Animals; Biological Transport; Cell Line; Cell Survival; Deoxyglucose; Glycation End Products, Advanced; Insulin; Kinetics; Mitogen-Activated Protein Kinase 3; Myoblasts; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Rats; Reactive Oxygen Species; Signal Transduction | 2006 |
Reducing the formation of glucose degradation products in peritoneal dialysis solutions by ultrahigh temperature ohmic heating.
Topics: Deoxyglucose; Dialysis Solutions; Glucose; Glyoxal; Hot Temperature; Peritoneal Dialysis; Pyruvaldehyde | 2007 |
A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry.
Topics: Calibration; Deoxyglucose; Gas Chromatography-Mass Spectrometry; Glyoxal; Humans; Pyruvaldehyde | 2008 |
Two dicarbonyl compounds, 3-deoxyglucosone and methylglyoxal, differentially modulate dermal fibroblasts.
Topics: Cell Line; Collagen; Deoxyglucose; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Humans; Integrin beta1; Protein Isoforms; Pyruvaldehyde; Skin; Transforming Growth Factor beta1 | 2010 |
Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.
Topics: Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Female; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Limit of Detection; Male; Middle Aged; Nails; Phenylenediamines; Pyruvaldehyde; Reproducibility of Results; Signal-To-Noise Ratio; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Survey of 1,2-dicarbonyl compounds in commercial honey of different floral origin.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Food Analysis; Furaldehyde; Glyoxal; Honey; Ketones; Limit of Detection; Phenols; Pyruvaldehyde | 2011 |
1,2-dicarbonyl compounds in commonly consumed foods.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Diet; Food Analysis; Furaldehyde; Galactose; Pyruvaldehyde | 2012 |
A nonradioisotope chemiluminescent assay for evaluation of 2-deoxyglucose uptake in 3T3-L1 adipocytes. Effect of various carbonyls species on insulin action.
Topics: 3T3-L1 Cells; Acrolein; Adipocytes; Aldehydes; Animals; Biological Transport; Chromans; Cytochalasin B; Deoxyglucose; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Luminescent Measurements; Mice; Pyruvaldehyde; Reproducibility of Results; Thiazolidinediones; Troglitazone | 2012 |
Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen.
Topics: Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glyoxal; Humans; Isotope Labeling; Perchlorates; Phenylenediamines; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors | 2014 |
Response surface methodology as optimization strategy for reduction of reactive carbonyl species in foods by means of phenolic chemistry.
Topics: Animals; Cattle; Cooking; Deoxyglucose; Food Additives; Food Preservation; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Milk; Phenols; Pyruvaldehyde | 2013 |
Two α-dicarbonyls downregulate migration, invasion, and adhesion of liver cancer cells in a p53-dependent manner.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Deoxyglucose; Down-Regulation; Drug Therapy, Combination; Genes, p53; Humans; Liver Neoplasms; Neoplasm Invasiveness; Pyruvaldehyde | 2013 |
Methylglyoxal impairs GLUT4 trafficking and leads to increased glucose uptake in L6 myoblasts.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Apoptosis; Biological Transport; Cell Line; Cell Membrane; Deoxyglucose; Glucose; Glucose Transporter Type 4; Insulin; Muscle, Skeletal; Myoblasts; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Rats; Signal Transduction | 2014 |
Free α-dicarbonyl compounds in coffee, barley coffee and soy sauce and effects of in vitro digestion.
Topics: Chromatography, High Pressure Liquid; Coffea; Coffee; Cooking; Deoxyglucose; Diacetyl; Digestion; Glyoxal; Hordeum; Hot Temperature; Humans; Models, Biological; Pyruvaldehyde; Soy Foods | 2014 |
Structure- and concentration-specific assessment of the physiological reactivity of α-dicarbonyl glucose degradation products in peritoneal dialysis fluids.
Topics: Animals; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyglucose; Dialysis Solutions; Galactose; Glucose; Glycation End Products, Advanced; Glyoxal; Ketoses; Mice; NIH 3T3 Cells; Peptides; Peritoneal Dialysis; Pyrones; Pyruvaldehyde; Ribonuclease, Pancreatic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Investigation of α-dicarbonyl compounds in baby foods by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Furaldehyde; Glyoxal; Humans; Infant Food; Infant Formula; Ketoses; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization | 2014 |
Post-Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study.
Topics: Atherosclerosis; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glyoxal; Humans; Hyperglycemia; Male; Mass Spectrometry; Middle Aged; Postprandial Period; Pyruvaldehyde | 2015 |
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde | 2016 |
Glucitol-core containing gallotannins inhibit the formation of advanced glycation end-products mediated by their antioxidant potential.
Topics: Acer; Antioxidants; Circular Dichroism; Deoxyglucose; Digoxin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Fructose; Gallic Acid; Glucosidases; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Glycosylation; Guanidines; Hydrolyzable Tannins; Hypoglycemic Agents; Inhibitory Concentration 50; Iron; Iron Chelating Agents; Plant Extracts; Polyphenols; Protein Structure, Secondary; Pyruvaldehyde; Serum Albumin, Bovine; Sorbitol | 2016 |
The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Cell Line; Deoxyglucose; Enzyme Activation; Exenatide; Gene Expression Profiling; Gene Silencing; Glucagon-Like Peptide-1 Receptor; Glucose; Humans; Insulin Resistance; Liraglutide; Mice; Muscle Fibers, Skeletal; Papio; Peptides; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvaldehyde; Rats; Signal Transduction; Time Factors; Venoms | 2016 |
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum | 2017 |
Maillard reaction and caramelization during hazelnut roasting: A multiresponse kinetic study.
Topics: Amino Acids; Cooking; Corylus; Deoxyglucose; Fructose; Furaldehyde; Glucose; Glyoxal; Kinetics; Maillard Reaction; Pyruvaldehyde; Sucrose | 2017 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry | 2017 |
Metformin attenuates myocardium dicarbonyl stress induced by chronic hypertriglyceridemia.
Topics: Animals; Deoxyglucose; Diet; Glutathione; Glyoxal; Hypertriglyceridemia; Hypoglycemic Agents; Lactoylglutathione Lyase; Male; Metformin; Myocardium; Pyruvaldehyde; Rats; Rats, Wistar; Stress, Physiological | 2018 |
Methylglyoxal as a prognostic factor in patients with chronic kidney disease.
Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Deoxyglucose; Diabetic Nephropathies; Disease Progression; Female; Humans; Japan; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvaldehyde; Renal Insufficiency, Chronic; Risk Factors; Time Factors; Up-Regulation | 2019 |
Elevated levels of α-dicarbonyl compounds in the plasma of type II diabetics and their relevance with diabetic nephropathy.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diacetyl; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde | 2019 |
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry | 2019 |
Measurement of α-dicarbonyl compounds in human saliva by pre-column derivatization HPLC.
Topics: Adult; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde; Saliva | 2019 |
Liraglutide Treatment Ameliorates Neurotoxicity Induced by Stable Silencing of Pin1.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Deoxyglucose; Gene Silencing; Humans; Insulin; Liraglutide; Neurons; Neuroprotective Agents; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pyruvaldehyde; Reactive Oxygen Species; Sirtuin 1 | 2019 |
Antibacterial activity of 1,2-dicarbonyl compounds and the influence of the in vitro assay system.
Topics: Anti-Bacterial Agents; Bacillus cereus; Deoxyglucose; Glyoxal; Kinetics; Microbial Sensitivity Tests; Pseudomonas fluorescens; Pyruvaldehyde; Salmonella enterica | 2020 |
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature | 2020 |
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde | 2020 |
5-Hydroxymethylfurfural accumulation plays a critical role on acrylamide formation in coffee during roasting as confirmed by multiresponse kinetic modelling.
Topics: Acrylamide; Amino Acids; Coffee; Deoxyglucose; Food-Processing Industry; Furaldehyde; Glucose; Glyoxal; Hot Temperature; Kinetics; Pyruvaldehyde; Sucrose | 2020 |
Reactive dicarbonyl compounds cause Calcitonin Gene-Related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Deoxyglucose; Drug Interactions; Inflammation; Mice; Mice, Inbred C57BL; Nerve Fibers; Peritoneum; Prostaglandins; Pyruvaldehyde; Skin; Temperature | 2020 |
Cytoprotective effects of a proprietary red maple leaf extract and its major polyphenol, ginnalin A, against hydrogen peroxide and methylglyoxal induced oxidative stress in human keratinocytes.
Topics: Acer; Apoptosis; Caspases; Cell Line; Cytoprotection; Deoxyglucose; Down-Regulation; Gallic Acid; Humans; Hydrogen Peroxide; Keratinocytes; Mitochondria; Oxidative Stress; Plant Extracts; Plant Leaves; Pyruvaldehyde; Reactive Oxygen Species | 2020 |
Increase in the peripheral blood methylglyoxal levels in 10% of hospitalized chronic schizophrenia patients.
Topics: Adult; Biomarkers; Case-Control Studies; Chronic Disease; Deoxyglucose; Female; Glyoxal; Hospitalization; Humans; Male; Middle Aged; Pyruvaldehyde; Schizophrenia; Stress, Physiological | 2021 |
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
Topics: Aged; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diet; Diet Surveys; Dietary Exposure; Fasting; Female; Glycation End Products, Advanced; Glyoxal; Humans; Linear Models; Male; Mass Spectrometry; Middle Aged; Netherlands; Optical Imaging; Pyruvaldehyde; Skin | 2022 |
Fasting Concentrations and Postprandial Response of 1,2-Dicarbonyl Compounds 3-Deoxyglucosone, Glyoxal, and Methylglyoxal Are Not Increased in Healthy Older Adults.
Topics: Aged; Animals; Deoxyglucose; Fasting; Female; Glucose; Glyoxal; Humans; Insulins; Magnesium Oxide; Male; Mice; Mice, Inbred C57BL; Pyruvaldehyde | 2022 |