pyruvaldehyde and carnosine

pyruvaldehyde has been researched along with carnosine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's8 (29.63)29.6817
2010's14 (51.85)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Chana, H; Hipkiss, AR1
Brownson, C; Hipkiss, AR1
Hipkiss, AR6
Brownson, C; Carrier, MJ; Hipkiss, AR1
Seidler, NW; Yeargans, GS1
Gugliucci, A; Menini, T2
Gugliucci, A1
Babizhayev, MA; Deyev, AI; Lankin, VZ; Savel'yeva, EL; Yegorov, YE1
Amberger, A; Fleming, T; Forsberg, E; Hecker, M; Hoffmann, GF; Lanthaler, B; Nawroth, P; Peters, V; Schmitt, CP; Wagner, AH; Yue, WW; Zschocke, J1
Aldini, G; Carini, M; Casali, G; Colzani, M; De Maddis, D; Vistoli, G1
Gromov, SV; Kosmachevskaya, OV; Nasybullina, EI; Novikov, AA; Shumaev, KB; Topunov, AF1
Bellahcène, A; Bellier, J; Bletard, N; Castronovo, V; Chiavarina, B; Dehon, R; Delvenne, P; Demetter, P; Durieux, F; Goldman, S; Hustinx, R; Lovinfosse, P; Nokin, MJ; Peulen, O; Sherer, F; Turtoi, A; Uchida, K; Verset, L1
Aydın, AF; Doğru-Abbasoğlu, S; Kalaz, EB; Koçak-Toker, N; Soluk-Tekkeşin, M; Uysal, M; Yılmaz, Z1
Aldini, G; Carini, M; Colzani, M; Gilardoni, E; Mazzolari, A; Rivaletto, C; Vistoli, G1
Amberger, A; Baelde, H; Fleming, T; Garbade, SF; Hecker, M; Klika, KD; Nawroth, P; Peters, V; Schmitt, CP; Singler, B; Thiel, C; Wagner, AH; Weigand, T; Yard, BA; Zschocke, J1
Albrecht, T; Allgayer, H; Bakker, S; Braun, JD; Breedijk, A; Hauske, SJ; Hofmann, BB; Krämer, BK; Pastene, DO; Rodriguez, A; Sticht, C; van den Born, J; von Ochsenstein, E; Yard, BA1
Kianpour, M; Yousefi, R1
Agirman, F; Bellahcène, A; Bellier, J; Blomme, A; Bours, V; Caprasse, M; Castronovo, V; Chiavarina, B; Costanza, B; Cusumano, PG; Durieux, F; Hustinx, R; Koopmansch, B; Lambert, F; Leung, HY; Lovinfosse, P; MacKay, GM; Maloujahmoum, N; Nokin, MJ; Peulen, O; Rademaker, G; Schalkwijk, CG; Scheijen, JL; Tiamiou, A1
Bakker, SJL; Krämer, BK; Pallavi, P; Pastene, DO; Rodriguez-Niño, A; van den Born, J; Yard, BA; Zhang, X1
Ghassem Zadeh, R; Yaylayan, V1
Elliott-Sale, KJ; Matthews, JJ; Sale, C; Santos, L; Turner, MD1

Reviews

5 review(s) available for pyruvaldehyde and carnosine

ArticleYear
Carnosine and protein carbonyl groups: a possible relationship.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:7

    Topics: Aldehydes; Amino Acids; Carnosine; Humans; Ketones; Proteins; Pyruvaldehyde

2000
NAD+ availability and proteotoxicity.
    Neuromolecular medicine, 2009, Volume: 11, Issue:2

    Topics: Animals; Carnosine; Cell Survival; Glycation End Products, Advanced; NAD; Neurons; Proteins; Pyruvaldehyde; Reactive Oxygen Species

2009
Energy metabolism, proteotoxic stress and age-related dysfunction - protection by carnosine.
    Molecular aspects of medicine, 2011, Volume: 32, Issue:4-6

    Topics: Aging; Animals; Carnosine; Energy Metabolism; Glycation End Products, Advanced; Glycolysis; Humans; Pyruvaldehyde

2011
Aging risk factors and Parkinson's disease: contrasting roles of common dietary constituents.
    Neurobiology of aging, 2014, Volume: 35, Issue:6

    Topics: Aging; Animals; Carnosine; Clinical Trials as Topic; Dietary Carbohydrates; Dietary Supplements; Double-Blind Method; Humans; Parkinson Disease; Pyruvaldehyde; Risk Factors; Treatment Outcome

2014
Glycotoxins: Dietary and Metabolic Origins; Possible Amelioration of Neurotoxicity by Carnosine, with Special Reference to Parkinson's Disease.
    Neurotoxicity research, 2018, Volume: 34, Issue:1

    Topics: Animals; Carnosine; Diet; Humans; Neurotoxicity Syndromes; Neurotoxins; Pyruvaldehyde; Tetrahydroisoquinolines

2018

Trials

1 trial(s) available for pyruvaldehyde and carnosine

ArticleYear
Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and
    The Journal of dermatological treatment, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Carnosine; Ceruloplasmin; Dermatologic Agents; Diabetes Complications; Double-Blind Method; Female; Free Radicals; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Oxidative Stress; Pyruvaldehyde; Schiff Bases; Skin Aging; Skin Diseases; Young Adult

2012

Other Studies

21 other study(ies) available for pyruvaldehyde and carnosine

ArticleYear
Carnosine protects proteins against methylglyoxal-mediated modifications.
    Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1

    Topics: Carnosine; Crystallins; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Lysine; Ovalbumin; Pyruvaldehyde

1998
Carnosine reacts with a glycated protein.
    Free radical biology & medicine, 2000, May-15, Volume: 28, Issue:10

    Topics: Aging; Animals; Carnosine; Glycoproteins; Glycosylation; Humans; In Vitro Techniques; Lysine; Ovalbumin; Oxidation-Reduction; Pyruvaldehyde

2000
Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups.
    Mechanisms of ageing and development, 2001, Sep-15, Volume: 122, Issue:13

    Topics: Aging; Animals; Antioxidants; Carnosine; Male; Ovalbumin; Pyruvaldehyde; Rats; Rats, Wistar

2001
Effects of thermal denaturation on protein glycation.
    Life sciences, 2002, Mar-01, Volume: 70, Issue:15

    Topics: Animals; Aspartate Aminotransferases; Carnosine; Enzyme Inhibitors; Glycation End Products, Advanced; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Hot Temperature; In Vitro Techniques; Nitroblue Tetrazolium; Protein Denaturation; Pyruvaldehyde; Swine

2002
The botanical extracts of Achyrocline satureoides and Ilex paraguariensis prevent methylglyoxal-induced inhibition of plasminogen and antithrombin III.
    Life sciences, 2002, Dec-06, Volume: 72, Issue:3

    Topics: Achyrocline; Antioxidants; Antithrombin III; Ascorbic Acid; Carnosine; Dose-Response Relationship, Drug; Guanidines; Ilex paraguariensis; Kinetics; Models, Biological; Plant Extracts; Plasminogen; Pyruvaldehyde

2002
A practical method to study functional impairment of proteins by glycation and effects of inhibitors using current coagulation/fibrinolysis reagent kits.
    Clinical biochemistry, 2003, Volume: 36, Issue:2

    Topics: alpha-Tocopherol; Antithrombin III; Ascorbic Acid; Blood Coagulation Tests; Carnosine; Chemistry, Clinical; Dose-Response Relationship, Drug; Drug Interactions; Fibrinolysis; Glycosylation; Guanidines; Heparin; Humans; Monosaccharides; Plasminogen; Pyruvaldehyde; Quercetin; Reagent Kits, Diagnostic

2003
The polyamines spermine and spermidine protect proteins from structural and functional damage by AGE precursors: a new role for old molecules?
    Life sciences, 2003, Apr-25, Volume: 72, Issue:23

    Topics: Animals; Antithrombin III; Carnosine; Cattle; Dimerization; Dose-Response Relationship, Drug; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Glucose-6-Phosphatase; Glycation End Products, Advanced; Glyceraldehyde; Histones; Humans; Plasminogen; Pyruvaldehyde; Spermidine; Spermine; Ubiquitin

2003
NAD(+) and metabolic regulation of age-related proteoxicity: A possible role for methylglyoxal?
    Experimental gerontology, 2010, Volume: 45, Issue:6

    Topics: Aging; Animals; Caenorhabditis elegans; Carnosine; Cell Survival; Gene Expression Regulation; Glycation End Products, Advanced; Mitochondria; NAD; Neurons; Proteins; Pyruvaldehyde; Reactive Oxygen Species

2010
Carnosine metabolism in diabetes is altered by reactive metabolites.
    Amino acids, 2015, Volume: 47, Issue:11

    Topics: Animals; Carnosine; Diabetes Mellitus; Dipeptidases; Humans; Hydrogen Peroxide; Iron; Mice; Mice, Mutant Strains; Mutation; Nitric Oxide; Pyruvaldehyde

2015
Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study.
    ChemMedChem, 2016, Aug-19, Volume: 11, Issue:16

    Topics: Aldehydes; Carnosine; Dose-Response Relationship, Drug; Glyoxal; Guanidines; Humans; Hydralazine; Malondialdehyde; Molecular Structure; Pyridoxamine; Pyruvaldehyde; Sequestering Agents; Structure-Activity Relationship

2016
New dinitrosyl iron complexes bound with physiologically active dipeptide carnosine.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2017, Volume: 22, Issue:1

    Topics: Carnosine; Iron; Nitrogen Oxides; Protein Binding; Pyruvaldehyde

2017
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
    International journal of molecular sciences, 2017, Jan-21, Volume: 18, Issue:1

    Topics: Adult; Aged; Animals; Carnosine; Cell Line, Tumor; Cell Proliferation; Chickens; Cohort Studies; Colorectal Neoplasms; Fluorodeoxyglucose F18; Glycolysis; Humans; Lactoylglutathione Lyase; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Pyrimidines; Pyruvaldehyde; Stress, Physiological

2017
The effect of carnosine on methylglyoxal-induced oxidative stress in rats.
    Archives of physiology and biochemistry, 2017, Volume: 123, Issue:3

    Topics: Advanced Oxidation Protein Products; Animals; Antioxidants; Carnosine; Glycation End Products, Advanced; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances

2017
Quenching activity of carnosine derivatives towards reactive carbonyl species: Focus on α-(methylglyoxal) and β-(malondialdehyde) dicarbonyls.
    Biochemical and biophysical research communications, 2017, 10-21, Volume: 492, Issue:3

    Topics: Carnosine; Chromatography, High Pressure Liquid; Malondialdehyde; Mass Spectrometry; Molecular Structure; Pyruvaldehyde

2017
Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:2

    Topics: Animals; Anserine; Carnosine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Glutathione; Glutathione Peroxidase; Glycation End Products, Advanced; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Oxidative Stress; Peptide Transporter 1; Podocytes; Polymers; Pyruvaldehyde; Serum Albumin; Superoxide Dismutase; Symporters

2018
Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells.
    Scientific reports, 2019, 02-04, Volume: 9, Issue:1

    Topics: Carnosine; Cell Cycle; Genes, cdc; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Tumor Suppressor Protein p53; Vascular Cell Adhesion Molecule-1

2019
Carnosine Prevents Different Structural Damages Induced by Methylglyoxal in Lens Crystallins.
    Cell biochemistry and biophysics, 2019, Volume: 77, Issue:4

    Topics: Animals; Carnosine; Cattle; Crystallins; Electrophoresis, Polyacrylamide Gel; Lens, Crystalline; Protein Stability; Protein Structure, Secondary; Pyruvaldehyde; Spectrophotometry

2019
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
    Cell reports, 2020, 02-04, Volume: 30, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Carnosine; Cell Line, Tumor; Cell Proliferation; Cetuximab; Clone Cells; Colorectal Neoplasms; Enzyme Activation; Free Radical Scavengers; Glycolysis; Glycosylation; HSP27 Heat-Shock Proteins; Humans; Male; Mechanistic Target of Rapamycin Complex 2; Mice, Inbred NOD; Mice, SCID; Middle Aged; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Pyruvaldehyde; Stress, Physiological

2020
Methylglyoxal induces p53 activation and inhibits mTORC1 in human umbilical vein endothelial cells.
    Scientific reports, 2021, 04-13, Volume: 11, Issue:1

    Topics: Autophagy; Carnosine; Cell Shape; Cell Survival; Glycosylation; Human Umbilical Vein Endothelial Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Tumor Suppressor Protein p53

2021
Interaction pattern of histidine, carnosine and histamine with methylglyoxal and other carbonyl compounds.
    Food chemistry, 2021, Oct-01, Volume: 358

    Topics: Acetaldehyde; Carnosine; Food Handling; Free Radical Scavengers; Glucose; Glyoxal; Histamine; Histidine; Imidazoles; Isotope Labeling; Pyruvaldehyde; Sugars; Tandem Mass Spectrometry; Temperature

2021
Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells.
    Amino acids, 2023, Volume: 55, Issue:3

    Topics: beta-Alanine; Carnosine; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Resistance; Magnesium Oxide; Muscle Fibers, Skeletal; Muscle, Skeletal; Pyruvaldehyde

2023