pyruvaldehyde and argpyrimidine

pyruvaldehyde has been researched along with argpyrimidine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's14 (53.85)29.6817
2010's9 (34.62)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Glomb, MA; Nagaraj, RH; Shipanova, IN1
Hattori, N; Maeda, S; Miyata, S; Mizuno, Y; Osawa, T; Oya, T; Uchida, K1
Glomb, MA; Nagaraj, RH; Rösch, D1
Arnold, BM; Chellan, P; Nagaraj, RH; Wilker, SC1
Glomb, MA; Jiang, C; Nagaraj, RH; Padayatti, PS; Uchida, K1
Crabb, JW; Kumar, R; Levison, B; Mehta, S; Nagaraj, RH; Oya-Ito, T; Padayatti, PS; Padival, AK; Sun, J; West, K1
Crabb, JW; Nagaraj, RH; Padival, AK1
Barroso, E; Cordeiro, C; Freire, A; Gomes, R; Martins, A; Monteiro, E; Pereira, P; Ponces Freire, A; Quintas, A; Sousa Silva, M1
Cordeiro, CA; Ferreira, AE; Freire, AP; Gomes, RA; Sousa Silva, M; Vicente Miranda, H1
Schalkwijk, CG; Stehouwer, CD; Uchida, K; van Bezu, J; van der Schors, RC; van Hinsbergh, VW1
Nagaraj, RH; Padival, S1
Biswas, A; Gangadhariah, MH; Lewis, S; Miyagi, M; Nagaraj, RH; Santoshkumar, P; Wang, B1
Azuma, M; Hirata, T; Kiyama, H; Konishi, H; Nakadate, Y; Shikata, K; Tachibana, T; Uchida, K; Yoshimura, S1
Brodehl, A; Engelbrecht, B; Gawlowski, T; Körfer, R; Milting, H; Niehaus, K; Stork, I; Stratmann, B; Tschoepe, D1
Bacílková, E; Bousová, I; Dobrijević, S; Drsata, J1
Kim, CS; Kim, J; Kim, JS; Kim, NH; Sohn, E1
Handa, O; Hirai, M; Hirata, I; Naito, Y; Okada, H; Oya-Ito, T; Suzuki, T; Takagi, T; Uchida, K; Uchiyama, K; Yoshikawa, T1
Becq, F; Boucherle, B; Décout, JL; Maurin, B; Molina, MC; Norez, C; Renard, BL1
Jung, DH; Kim, JS; Kim, KM; Kim, YS; Lee, J1
Jo, K; Kim, CS; Kim, J; Kim, JS; Kim, OS; Sohn, E1
Ding, D; Liu, XM; Pan, C; Xia, YM; Zhan, N; Zou, XY1
Antognelli, C; Gambelunghe, A; Muzi, G; Talesa, VN1
Amicarelli, F; Cacchio, M; Cordone, V; Di Emidio, G; Falone, S; Grannonico, M; Santini, SJ; Tatone, C1
Morales, FJ; Navarro, M1
Gusev, NB; Sudnitsyna, MV1
Mandal, P; Parwani, K; Patel, D; Patel, F1

Other Studies

26 other study(ies) available for pyruvaldehyde and argpyrimidine

ArticleYear
Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct.
    Archives of biochemistry and biophysics, 1997, Aug-01, Volume: 344, Issue:1

    Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Glyceraldehyde; Guanidines; Kinetics; Maillard Reaction; Molecular Structure; Monosaccharides; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Spectrometry, Fluorescence; Spectrophotometry

1997
Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts.
    The Journal of biological chemistry, 1999, Jun-25, Volume: 274, Issue:26

    Topics: Animals; Antibodies, Monoclonal; Arginine; Brain Chemistry; Chromatography, High Pressure Liquid; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kidney; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Models, Chemical; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Rats

1999
N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:1

    Topics: Acetone; Aldehydes; Beer; Chromatography, High Pressure Liquid; Color; Deoxyribose; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Ornithine; Pyrimidines; Pyruvaldehyde

2001
Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine.
    Analytical biochemistry, 2001, Volume: 290, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Arginine; Blood Proteins; Diabetes Mellitus; Humans; Lens, Crystalline; Lysine; Middle Aged; Ornithine; Pyrimidines; Pyruvaldehyde

2001
High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells.
    Current eye research, 2001, Volume: 23, Issue:2

    Topics: Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glucose; Glycation End Products, Advanced; Maillard Reaction; Microscopy, Confocal; Ornithine; Pyrimidines; Pyruvaldehyde; Retinal Vessels

2001
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification.
    Biochemistry, 2003, Sep-16, Volume: 42, Issue:36

    Topics: Alcohol Dehydrogenase; alpha-Crystallins; Anilino Naphthalenesulfonates; Animals; Arginine; Ascorbic Acid; Cattle; Citrate (si)-Synthase; Humans; Insulin; Lens, Crystalline; Lysine; Middle Aged; Molecular Chaperones; Monosaccharides; Ornithine; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; Pyruvaldehyde

2003
Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells.
    FEBS letters, 2003, Sep-11, Volume: 551, Issue:1-3

    Topics: Animals; Cells, Cultured; Cytochrome c Group; Diabetes Mellitus, Experimental; Glomerular Mesangium; Heat-Shock Proteins; Kidney Glomerulus; Maillard Reaction; Male; Ornithine; Proteins; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2003
Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy.
    The Biochemical journal, 2005, Jan-15, Volume: 385, Issue:Pt 2

    Topics: Adipose Tissue; Adult; Amyloid; Amyloid Neuropathies, Familial; Female; Glycation End Products, Advanced; Humans; Maillard Reaction; Male; Ornithine; Pyrimidines; Pyruvaldehyde

2005
Protein glycation in Saccharomyces cerevisiae. Argpyrimidine formation and methylglyoxal catabolism.
    The FEBS journal, 2005, Volume: 272, Issue:17

    Topics: Gene Deletion; Genes, Fungal; Glycoproteins; Glycosylation; Humans; Kinetics; Models, Biological; Ornithine; Phenotype; Pyrimidines; Pyruvaldehyde; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2005
Heat-shock protein 27 is a major methylglyoxal-modified protein in endothelial cells.
    FEBS letters, 2006, Mar-06, Volume: 580, Issue:6

    Topics: Cells, Cultured; Endothelial Cells; Glucose; Glutathione; Glycation End Products, Advanced; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Lactoylglutathione Lyase; Molecular Chaperones; Neoplasm Proteins; Ornithine; Pyrimidines; Pyruvaldehyde

2006
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
    Ophthalmic research, 2006, Volume: 38, Issue:5

    Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lens Diseases; Lens, Crystalline; Lysine; Maillard Reaction; Male; Organ Culture Techniques; Ornithine; Pyridoxamine; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2006
Chemical modulation of the chaperone function of human alphaA-crystallin.
    Journal of biochemistry, 2008, Volume: 144, Issue:1

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Crystallins; Homoarginine; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Mass Spectrometry; Methylurea Compounds; Molecular Chaperones; Ornithine; Protein Conformation; Protein Subunits; Pyrimidines; Pyruvaldehyde

2008
The formation of argpyrimidine, a methylglyoxal-arginine adduct, in the nucleus of neural cells.
    Biochemical and biophysical research communications, 2009, Jan-09, Volume: 378, Issue:2

    Topics: Animals; Arginine; Cell Nucleus; Cerebral Cortex; DNA Adducts; Lactoylglutathione Lyase; Mice; Mice, Inbred ICR; Neurons; Ornithine; Pyrimidines; Pyruvaldehyde

2009
Heat shock protein 27 modification is increased in the human diabetic failing heart.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:8

    Topics: Adult; Aged; Animals; Cardiomyopathies; Cell Line; Diabetes Complications; Female; Heart; HSP27 Heat-Shock Proteins; Humans; Male; Middle Aged; Myocardium; Ornithine; Phosphorylation; Pyrimidines; Pyruvaldehyde; Rats

2009
Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid.
    Molecular and cellular biochemistry, 2009, Volume: 331, Issue:1-2

    Topics: Animals; Aspartate Aminotransferases; Blotting, Western; Citrates; Cross-Linking Reagents; Fluorescence; Glycation End Products, Advanced; Glycosylation; Ornithine; Protein Structure, Quaternary; Pyrimidines; Pyruvaldehyde; Sus scrofa; Uric Acid

2009
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Caspase 3; Cell Line; Deoxyguanosine; DNA Damage; Epithelial Cells; Glycation End Products, Advanced; Humans; Lens, Crystalline; Ornithine; Oxidative Stress; Pyridoxamine; Pyrimidines; Pyruvaldehyde

2010
Impaired gastric ulcer healing in diabetic mice: role of methylglyoxal.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60 Suppl 7

    Topics: Animals; Anti-Ulcer Agents; Blood Glucose; Diabetes Mellitus, Experimental; Gastric Mucosa; Glycation End Products, Advanced; Glycosylation; Male; Mice; Mice, Inbred C57BL; Ornithine; Peroxiredoxin VI; Protein Processing, Post-Translational; Proteins; Pyrimidines; Pyruvaldehyde; Regeneration; Severity of Illness Index; Stomach Ulcer; Thiadiazoles; Thiazolidines; Wound Healing

2009
An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Animals; Chemistry, Physical; CHO Cells; Cricetinae; Cricetulus; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Discovery; Molecular Conformation; Ornithine; Pyrimidines; Pyruvaldehyde; Stereoisomerism; Structure-Activity Relationship

2011
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose.
    Experimental cell research, 2012, Jan-15, Volume: 318, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Apoptosis; Caspase 3; Cell Line; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus; Glycation End Products, Advanced; Hyperglycemia; Lactoylglutathione Lyase; Lipid Peroxidation; Mesangial Cells; Mice; Mitochondria; Ornithine; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pyrimidines; Pyruvaldehyde

2012
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo.
    Experimental & molecular medicine, 2012, Feb-29, Volume: 44, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Epithelial Cells; Glycation End Products, Advanced; Lens, Crystalline; Male; Ornithine; Pyrimidines; Pyruvaldehyde; Rats

2012
Glyoxalase I is differentially expressed in cutaneous neoplasms and contributes to the progression of squamous cell carcinoma.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Disease Progression; Humans; Lactoylglutathione Lyase; Male; Mice; Neoplasm Invasiveness; NF-kappa B; Ornithine; Pyrimidines; Pyruvaldehyde; Skin Neoplasms; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2015
Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype.
    Free radical biology & medicine, 2016, Volume: 92

    Topics: Bronchi; Cell Transformation, Neoplastic; Epithelial Cells; Epithelial-Mesenchymal Transition; HSP70 Heat-Shock Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Lactoylglutathione Lyase; MicroRNAs; Ornithine; Oxidative Stress; Phenotype; Pyrimidines; Pyruvaldehyde; Reactive Oxygen Species; Signal Transduction; Silicon Dioxide; Smad Proteins

2016
Regular and Moderate Exercise Counteracts the Decline of Antioxidant Protection but Not Methylglyoxal-Dependent Glycative Burden in the Ovary of Reproductively Aging Mice.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Aging; Animals; Antioxidants; Catalase; Female; Glutathione; Glutathione Peroxidase; Lactoylglutathione Lyase; Mice; Ornithine; Ovary; Oxidative Stress; Physical Conditioning, Animal; Protein Carbonylation; Pyrimidines; Pyruvaldehyde; Reactive Oxygen Species; Reproduction; Superoxide Dismutase; Thiolester Hydrolases

2016
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
    Food research international (Ottawa, Ont.), 2017, Volume: 92

    Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Is the small heat shock protein HspB1 (Hsp27) a real and predominant target of methylglyoxal modification?
    Cell stress & chaperones, 2019, Volume: 24, Issue:2

    Topics: Antibodies, Monoclonal; Binding Sites; Heat-Shock Proteins; HeLa Cells; HSP27 Heat-Shock Proteins; Humans; Molecular Chaperones; Mutation; Ornithine; Peptides; Protein Binding; Protein Processing, Post-Translational; Pyrimidines; Pyruvaldehyde

2019
Protective Effects of Swertiamarin against Methylglyoxal-Induced Epithelial-Mesenchymal Transition by Improving Oxidative Stress in Rat Kidney Epithelial (NRK-52E) Cells.
    Molecules (Basel, Switzerland), 2021, May-07, Volume: 26, Issue:9

    Topics: Animals; Cattle; Cell Shape; Cell Survival; Chromatography, High Pressure Liquid; Endoplasmic Reticulum Stress; Epithelial Cells; Epithelial-Mesenchymal Transition; Fluorescence; Fructose; Glycation End Products, Advanced; Glycosylation; Inflammation; Iridoid Glucosides; Kidney; Ligands; Malondialdehyde; Mass Spectrometry; Ornithine; Oxidative Stress; Protective Agents; Protein Carbonylation; Pyrimidines; Pyrones; Pyruvaldehyde; Rats; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared

2021