pyruvaldehyde and alpha-synuclein

pyruvaldehyde has been researched along with alpha-synuclein in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Choi, KY; Lee, D; Paik, SR; Park, CW1
Dai, R; Deng, Y; Ding, W; Lin, F; Peng, L; Qing, H; Ullah, K; Xie, B1
Asiago, JM; Aslam, K; Drendel, HM; Goode, KM; Hazbun, TR; Paul, LN; Rochet, JC; Tsai, CJ1
Breda, C; Cordeiro, C; Darendelioglu, E; de Oliveira, RM; Engelender, S; Enguita, FJ; Ferreira, DG; Giorgini, F; Gomes, MA; Heinrich, M; Jovin, TM; Klucken, J; Lashuel, HA; Lopes, LV; Martins, IC; Munari, F; Oliveira, LMA; Oliveira, M; Outeiro, TF; Penque, D; Ponces-Freire, A; Quintas, A; Riess, O; Rodrigues, EF; Rott, R; Santos, NC; Simões, T; Szego, ÉM; Vicente Miranda, H; Xiang, W; Zamolo, I; Zweckstetter, M1
König, A; Outeiro, TF; Vicente Miranda, H1
Kalivendi, SV; Rao, SP; Sharma, N1
Chegão, A; Enguita, FJ; Fernandes Gomes, B; Oliveira, MS; Outeiro, TF; Vicente Miranda, H1
Buell, AK; Dominguez-Meijide, A; Farzadfard, A; König, A; Nielsen, J; Otzen, DE; Outeiro, TF; Petersen, SV; Vasili, E1

Reviews

1 review(s) available for pyruvaldehyde and alpha-synuclein

ArticleYear
Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson's Disease.
    Journal of Parkinson's disease, 2018, Volume: 8, Issue:1

    Topics: alpha-Synuclein; Diabetes Complications; Glucose; Glycation End Products, Advanced; Glycosylation; Homeostasis; Humans; Hypoglycemic Agents; Maillard Reaction; Parkinson Disease; Protein Processing, Post-Translational; Pyruvaldehyde; Risk Factors

2018

Other Studies

7 other study(ies) available for pyruvaldehyde and alpha-synuclein

ArticleYear
The modification of alpha-synuclein by dicarbonyl compounds inhibits its fibril-forming process.
    Biochimica et biophysica acta, 2009, Volume: 1794, Issue:3

    Topics: alpha-Synuclein; Cell Line, Tumor; Circular Dichroism; Glycation End Products, Advanced; Glyoxal; HeLa Cells; Humans; Liposomes; Oxidation-Reduction; Protein Conformation; Protein Structure, Quaternary; Pyruvaldehyde; Temperature

2009
A newly discovered neurotoxin ADTIQ associated with hyperglycemia and Parkinson's disease.
    Biochemical and biophysical research communications, 2015, Apr-10, Volume: 459, Issue:3

    Topics: alpha-Synuclein; Animals; Brain; Cell Death; Cell Line; Diabetes Mellitus, Experimental; Dopaminergic Neurons; Glucose; Humans; Hyperglycemia; Mice; Mice, Transgenic; Mutant Proteins; Neurotoxins; Parkinson Disease; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2015
Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process.
    The Journal of biological chemistry, 2015, Oct-09, Volume: 290, Issue:41

    Topics: alpha-Synuclein; Amino Acid Sequence; Catalytic Domain; Heat-Shock Proteins; Humans; Lactic Acid; Lactoylglutathione Lyase; Molecular Sequence Data; Oxidative Stress; Prions; Protein Aggregates; Protein Folding; Protein Multimerization; Protein Structure, Quaternary; Pyruvaldehyde; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2015
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.
    Brain : a journal of neurology, 2017, May-01, Volume: 140, Issue:5

    Topics: Aging; alpha-Synuclein; Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Disease Models, Animal; Drosophila; Enzyme Inhibitors; Female; Glycosylation; Hippocampus; Humans; Induced Pluripotent Stem Cells; Male; Mice; Mice, Transgenic; Neurodegenerative Diseases; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Pyruvaldehyde; Rats; Yeasts

2017
The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
    Free radical biology & medicine, 2019, 05-01, Volume: 135

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Animals; Cell Line; Dopaminergic Neurons; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Mice; Oxidative Stress; Parkinson Disease; Pars Compacta; Protein Aggregates; Protein Deglycase DJ-1; Pyruvaldehyde; Substrate Specificity

2019
Hsp27 reduces glycation-induced toxicity and aggregation of alpha-synuclein.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:5

    Topics: alpha-Synuclein; Brain Neoplasms; Glioma; Glycosylation; Heat-Shock Proteins; Humans; Molecular Chaperones; Protein Aggregates; Pyruvaldehyde; Tumor Cells, Cultured

2020
Glycation modulates alpha-synuclein fibrillization kinetics: A sweet spot for inhibition.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:5

    Topics: alpha-Synuclein; Humans; Kinetics; Monosaccharides; Protein Aggregates; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Pyruvaldehyde

2022