Page last updated: 2024-08-26

pyrroline and pyrroles

pyrroline has been researched along with pyrroles in 160 studies

Research

Studies (160)

TimeframeStudies, this research(%)All Research%
pre-199016 (10.00)18.7374
1990's1 (0.63)18.2507
2000's57 (35.63)29.6817
2010's67 (41.88)24.3611
2020's19 (11.88)2.80

Authors

AuthorsStudies
Caputi, AP; Costa, G; Ruggeri, P; Saija, A1
Basselier, JJ; Bazire, M; Cassier, P; Clément, JL; Escoubas, P; Lange, C; Lemaire, M1
Desiderio, MA; Perin, A; Sessa, A1
Lawson, J; Williams, CH1
Cantin, LD; Griffin, AM; Hanessian, S1
Buchwald, SL; Yun, J1
Chen, W; Coleman, RS1
Green, MP; Hayes, CJ; Prodger, JC; Sherlock, AE1
Dieter, RK; Yu, H1
Chen, J; Chi, ZQ; Long, YQ; Mou, QY; Zhou, DH; Zhu, YC1
Batey, RA; Powell, DA1
Dooley, DM; Lee, Y; Ling, KQ; Lu, X; Sayre, LM; Shepard, EM; Silverman, RB1
Faist, V; Hofmann, T; Lindenmeier, M1
Brüdgam, I; Flögel, O; Hartl, H; Okala Amombo, MG; Reissig, HU; Zahn, G1
Gwoździński, K; Jóźwiak, Z; Kania, K; Koceva-Chyła, A; Sokal, A1
Gwoździński, K; Jóźwiak, Z; Koceva-Chyła, A; Kochman, A; Stolarska, A1
Dannhardt, G; Fiebich, B; Ulbrich, H1
Doyle, MP; Gronenberg, LS; Hu, W; Yan, M1
Ichinose, R; Ito, M; Iwabuchi, J; Iwasaki, T; Kinoshita, A; Kodama, S; Mio, S; Miura, T; Miyake, T; Nagai, J; Nakagawa, H; Obayashi, T; Okui, H; Takashio, M; Tanaka, K; Yokoi, S1
STRECKER, HJ2
ADAMS, E; GOLDSTONE, A3
SKURSKY, L1
BACHRACH, U1
HEKELOVA, J; MACHOLAN, L; ZOBAC, P1
MACHOLAN, L1
PEISACH, J; STRECKER, HJ1
Dai, LX; Hou, XL; Tu, T1
Halpern, HJ; Ichikawa, K; Mailer, C; Nielsen, R; Pou, S; Robinson, BH; Rosen, GM; Tsai, P1
Chen, Z; Gregson, SJ; Howard, PW; Thurston, DE1
Ilangovan, G; Kuppusamy, P; Zweier, JL1
Basosi, R; Busi, E; Elisei, F; Fusi, S; Latterini, L; Migani, A; Olivucci, M; Pepi, A; Ponticelli, F; Sampedro, D; Zanirato, V1
Aso, Y; Inukai, T; Sekine, K; Takanashi, K; Takebayashi, K; Yoshida, N; Yoshihara, K1
Krzycki, JA1
Höfner, G; Mayer, P; Poschenrieder, H; Stachel, HD1
Nohl, H; Rohr-Udilova, N; Rosenau, T; Stadtmüller, R; Stolze, K1
Davide, JP; Farrell, L; Kohl, NE; Lobell, RB; Sepp-Lorenzino, L; South, VJ; Tao, W; Zhang, Y1
Glaser, R; Loeppky, RN; Wu, H1
Cantín, A; Estornell, E; González, MC; López-Gresa, MP; Miranda, MA; Moya, P; Peris, E; Primo, J; Romero, V1
Bowen, EG; Wardrop, DJ1
Ihle, DC; White, JD1
Bosnjakovic, A; Schlick, S1
Funk, RL; Huntley, RJ1
Sharp, JS; Tomer, KB1
Bhalay, G; Bhatti, FL; Cowley, AR; Donohoe, TJ; Linney, ID; Nieuwenhuys, WF; Rigby, CL; Thomas, RE1
Amano, S; Fukayama, M; Kaji, Y; Nagai, R; Oshika, T; Takazawa, Y1
Ran, C; Sayre, LM; Zhang, Y; Zhou, G1
Portela-Cubillo, F; Scott, JS; Walton, JC1
Cui, SL; Wang, J; Wang, YG1
BATTISTONI, L1
Antipin, MY; Evdokimov, NM; Kornienko, A; Luchetti, G; Magedov, IV; Manpadi, M; Steelant, WF; Tongwa, P; Van Slambrouck, S1
Gong, LZ; Guo, C; Xue, MX; Zhu, MK1
Fox, CB; Lebel, LA; O'Neill, BT; Procko, K; Yohannes, D1
Liu, L; Wang, C; Xi, Z; Yu, N; Zhang, WX; Zhao, F1
Duarte, MT; Figueira, CA; Gomes, CS; Gomes, PT1
Jacobi, PA; Tassa, C; Wang, H1
Portela-Cubillo, F; Scanlan, EM; Scott, JS; Walton, JC1
Brichacek, M; Lee, D; Njardarson, JT1
KNOTT, EB1
Cheeseman, MD; Donohoe, TJ; Kershaw, JA; O'Riordan, TJ1
Eickmeier, H; Hideg, K; Reuter, H; Steinhoff, HJ; Zielke, V1
Caselli, A; Cenini, S; Fantauzzi, S; Gallo, E; Piangiolino, C; Ragaini, F; Re, N1
Hu, W; Yang, L; Yue, Y; Zhai, C; Zhu, Y1
Brandi, A; Cordero, FM; de Meijere, A; Salvati, M; Vurchio, C1
Campos, PJ; Fusi, S; Olivucci, M; Rivado-Casas, L; Sampedro, D; Zanirato, V1
Cornée, C; David, M; Gouault, N; Le Roch, M; Uriac, P1
Armstrong, BD; Han, S; Shea, JE; Soto, P1
Fan, J; Gao, L; Wang, Z1
Boddu, SP; Du, M; Hua, Y; Kandadi, MR; Li, J; Rajanna, PK; Ren, J; Sreejayan, N; Unnikrishnan, MK1
Bourbon, P; Cosner, CC; Helquist, P; Huang, AY; Mariani, CJ; Markiewicz, JT; Maxfield, FR; Rosenbaum, AI; Rujoi, M; Wiest, O1
Alvarez, E; Carmona, AT; Moreno-Clavijo, E; Moreno-Vargas, AJ; Reissig, HU; Robina, I1
Jana, R; Pahadi, NK; Paley, M; Tunge, JA; Waetzig, SR1
Helquist, P; Iska, VB; Verdolino, V; Wiest, O1
PLOQUIN, J1
An, J; Chen, JR; Cheng, Y; Li, F; Lu, LQ; Xiao, WJ; Zhang, JJ1
Castellano, S; Conti, P; Pinto, A; Sbardella, G; Tamborini, L; Viviano, M1
Patel, A; Rohr-Udilova, N; Rosenau, T; Stolze, K1
Brichacek, M; Njardarson, JT; Plichta, A; Villalobos, MN1
Samec, JS; Sawadjoon, S1
He, Z; Song, H; Sun, H; Tian, J; Zhou, R1
Bocian, DF; Deans, RM; Diers, JR; Holten, D; Kee, HL; Kim, HJ; Kirmaier, C; Krayer, M; Lindsey, JS; Sluder, CE; Yang, E1
Brock, A; Cellitti, SE; Chiu, HP; Crossgrove, T; Fan, Q; Geierstanger, BH; Grünewald, J; Hao, X; Jones, DH; Lesley, SA; Okach, L; Ou, W; Patterson, P; Quinn, LL; Uno, T1
Burgess, K; Ioerger, TR; Ko, E; Perez, LM; Raghuraman, A1
Abbandonato, G; Beltram, F; Bizzarri, R; Nifosì, R; Signore, G; Voliani, V1
Bokesch, HR; Bottaro, DP; Gardella, RS; Linehan, WM; McKee, TC; McMahon, JB; Rabe, DC1
Kuramoto, T; Mitsukura, K; Nagasawa, T; Shinoda, S; Suzuki, M; Yoshida, T1
Li, L; Zhang, J1
Chen, R; Cole, N; Ho, KK; Kumar, N; Rice, SA; Willcox, MD1
Han, X; Lu, Y; Wang, Y; Zhong, F1
Lin, Z; Liu, J; Luo, X; Shu, M; Wang, Y; Yang, W1
Kawai, H; Kitayama, T; Matsumoto, T; Sato, H; Shibata, N; Shiro, M; Tokunaga, E1
Audebert, A; Boulanger, R; Bry, X; Gunata, Z; Maraval, I; Poonlaphdecha, J; Roques, S1
Yu, X; Zhang, J; Zhou, G1
Kawai, H; Okusu, S; Sato, H; Shibata, N; Shiro, M; Tokunaga, E1
Blanco-Lomas, M; Campos, PJ; Samanta, S; Sampedro, D; Woolley, GA1
Andrews, IP; Blank, BR; Kwon, O1
Chen, Z; Gao, L; Jiang, H; Li, J; Liu, S; Shu, H; Zheng, S; Zhu, Q1
Galvagno, S; Grassi, G; Iannazzo, D; Lanza, M; Milone, C; Piperno, A; Pistone, A; Scala, A1
Bagryanskaya, EG; Gatilov, YV; Grigor'ev, IA; Kirilyuk, IA; Krumkacheva, OA; Polienko, YF; Strizhakov, RK1
Coeffard, V; Desmarchelier, A; Greck, C; Moreau, X1
Chandan, N; Moloney, MG; Thompson, AL1
Brandi, A; Cordero, FM; Lumini, M; Vurchio, C1
Briand, J; Fusi, S; Haacke, S; Léonard, J; Olivucci, M; Paccani, RR; Schapiro, I1
Ayaydin, F; Hideg, É; Hideg, K; Kálai, T1
Li, Z; Shao, X; Shi, L; Xu, X; Xu, Z; Ye, Z1
Cai, X; Chen, Z; Liu, S; Lv, L; Zheng, S; Zhu, Q1
Karthik, G; Rajasekaran, T; Reddy, BV; Sridhar, B1
Kuznietsova, HM; Ogloblya, OV; Rybalchenko, VK1
Bagryanskaya, EG; Fedin, MV; Jicsinszky, L; Krumkacheva, OA; Marque, SR; Polovyanenko, DN1
Bousquet, P; Chetrite, G; Fellmann, L; Fève, B; Gasparik, V; Gigou, L; Greney, H; Julien, C; Lacolley, P; Max, JP; Muscat, A; Niederhoffer, N; Oréa, V; Pizard, A; Regnault, V1
Asano, K; Boyd, SA; De Meese, LA; Endo, S; Fukumoto, S; Gauthier, C; Habuka, N; Hasui, T; Matsui, H; Mizukami, A; Ohra, T; Ohyabu, N; Siedem, CS; Sogabe, S; Tang, TP1
Cui, B; Ren, J; Wang, Z1
Abdelazeem, AH; Abdellatif, KR; Arafa, el-SA; Gouda, AM1
Oe, K; Ohfune, Y; Shinada, T1
Bacher, A; Beck, P; Groll, M; Quitterer, F1
Omotuyi, OI1
Belding, L; Dudding, T; Fan, YC; Henry, CE; Kwon, O; Martin, TJ; Xu, Q1
Andruniów, T; Fusi, S; Loppnow, GR; Olivucci, M; Sasidharanpillai, S; Schapiro, I1
Berg, K; Paletta, JT; Rajca, A; Rajca, S; Reinhart, E; Wang, Y1
Matsumoto, K; Miura, T; Murakami, M; Tanaka, T1
Du, HJ; Sun, H; Wen, X; Xu, QL; Zhen, L1
Feng, X; Lin, L; Liu, X; Xia, Y; Zheng, H1
Abderrahim, R; Agrebie, A; Ben Abdessalem, A; Dos Santos, A; El Kaïm, L; Khomenko, A; Komesky, A1
Gerratana, B; Li, W; Rokita, SE; Saha, S1
Chu, JC; Oberg, KM; Rovis, T; Zhang, WZ1
Butterworth, S; Clayden, J; Tait, MB1
Chen, J; Guo, Y; Li, H; Li, J; Wang, J; Wang, W1
Blum, SA; Chong, E1
Adamo, MF; Disetti, P; Moccia, M; Salazar Illera, D; Suresh, S1
Chogii, I; Njardarson, JT1
Boulanger, R; Gantet, P; Gunata, Z; Maraval, I; Menut, C; Morère, A; Poonlaphdecha, J; Sauvage, FX; Wüst, M1
Cai, L; Kwon, O; Zhang, K1
Huang, C; Xiao, Y; Yang, J; Zeng, Y; Zhang, J; Zhou, X1
Alings, C; Consentius, P; Gohlke, U; Heinemann, U; Kaupp, M; Loll, B; Müller, C; Müller, R; Risse, T; Teutloff, C; Wahl, MC1
Monza, J; Signorelli, S1
Amicucci, A; Antonini, E; Battistelli, S; Benedetti, S; Catalani, S; De Crescentini, L; Lombardi, P; Mantellini, F; Mari, G; Palma, F; Santeusanio, S1
Domnick, C; Eggert, F; Hagelueken, G; Kath-Schorr, S; Schiemann, O1
Bousquet, P; Gomes, F; Gonçalves-de-Albuquerque, C; Machado, MV; Nascimento, AR; Tibiriçá, E1
Kazemi Chegeni, Z; Soleymani, M1
Asanbaeva, N; Bagryanskaya, EG; Chernyak, EI; Dobrynin, S; Glazachev, YI; Gorodetskii, AA; Kirilyuk, IA; Rybalova, TV; Zhurko, IF1
Anil, SM; Kiran, KR; Rajeev, N; Sadashiva, MP; Shobith, R; Sudhanva, MS; Swaroop, TR; Vinayaka, AC1
Chen, F; Dai, C; Huang, Y; Liao, H; Liu, S; Liu, T; Sang, H; Yang, J; Zhu, Q1
Bognár, B; Hideg, K; Isbera, M; Jekő, J; Kálai, T; Sár, C1
He, L; Lai, R; Liu, J; Luo, H; Tang, X; Xing, P; Zhang, T; Zheng, A1
Chen, M; Lu, A; Si, W; Wang, X; Yan, J; Yang, C; Zhang, L1
Altamura, C; Bruno, C; Budriesi, R; Carocci, A; Catalano, A; Cavalluzzi, MM; Corbo, F; De Palma, A; Desaphy, JF; Franchini, C; Habtemariam, S; Lentini, G; Lovece, A; Micucci, M; Milani, G; Passeri, GI; Roselli, M; Toma, M1
Asahi, K; Hasegawa, T; Hata, K; Horiguchi, T; Kai, H; Kameyama, T; Kanda, Y; Kurihara, N; Oohara, M; Shimada, S; Shinohara, S; Tada, Y; Takahara, Y; Takahashi, F; Takeyama, C; Tanaka, Y; Taniguchi, E; Taoda, Y; Tobinaga, H; Tomari, M; Yagi, S; Yamamoto, S1
Almeida, A; Dias, CJ; Faustino, MAF; Gomes, ATPC; Ladeira, BMF; Moura, NMM; Neves, MGPMS; Tomé, AC1
Aksahin, M; Ayar, A; Gül, M; Mesci, S; Yazgan, B; Yıldırım, T1
Ashizawa, N; Iwanaga, T; Kobashi, S; Matsumoto, K; Uda, J1
Bi, J; Liu, Q; Tan, Q; Wu, H; Zhang, G1
Andreidesz, K; Bagone Vantus, V; Bognar, Z; Gallyas, F; Isbera, M; Kalai, T; Koszegi, B; Kovacs, D; Kovacs, K; Szabo, A; Vamos, E1
Catti, L; Huck, F; Reber, GL; Tiefenbacher, K1
Cong, J; Li, L; Yang, X; Yin, M; Zhao, J; Zi, Q1
Han, B; Huang, W; Jiang, J; Li, X; Luo, QQ; Tian, Z; Yan, ZH; Zhan, G1
Atmaca, H; Ilhan, S; Korkmaz, E; Zora, M1
Cen, M; Duan, S; Kong, X; Li, CY; Xu, H; Xu, ZF1
Li, YJ; Shi, DY; Shi, T; Wang, B; Wang, YF; Wang, ZM1

Reviews

1 review(s) available for pyrroline and pyrroles

ArticleYear
Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases.
    Current opinion in chemical biology, 2004, Volume: 8, Issue:5

    Topics: Amides; Codon; Corrinoids; Dimethylamines; Imines; Lysine; Methane; Methylamines; Methyltransferases; Models, Molecular; Pyrroles

2004

Other Studies

159 other study(ies) available for pyrroline and pyrroles

ArticleYear
Influence of several aldehyde dehydrogenase and aldehyde reductase inhibitors on diamine oxidase in rat brain.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:2

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehydes; Amine Oxidase (Copper-Containing); Animals; Brain; Male; Monoamine Oxidase Inhibitors; Putrescine; Pyrroles; Rats; Rats, Inbred Strains

1986
Alkaloid venom of European ants in the genus Monomorium. Site of synthesis, identification and quantification.
    Experimental biology, 1988, Volume: 48, Issue:1

    Topics: Animals; Ant Venoms; Ants; Arthropod Venoms; Exocrine Glands; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; Microscopy, Electron, Scanning; Molecular Structure; Pyrroles; Pyrrolidines

1988
Induction of diamine oxidase activity in rat kidney during compensatory hypertrophy.
    Biochimica et biophysica acta, 1982, Feb-02, Volume: 714, Issue:2

    Topics: Acetaldehyde; Amine Oxidase (Copper-Containing); Animals; Cycloheximide; Dactinomycin; Enzyme Induction; Hypertrophy; Kidney; Male; Nephrectomy; Phenobarbital; Polyamines; Putrescine; Pyrroles; Rats; Rats, Inbred Strains

1982
Mechanism-based inhibition of monoamine oxidase by 3-aryl-Delta3-pyrrolines.
    The Biochemical journal, 1998, Nov-15, Volume: 336 ( Pt 1)

    Topics: Animals; Chromatography, High Pressure Liquid; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrroles; Rats

1998
Asymmetric synthesis of functionalized carbocycles and heterocycles.
    Chirality, 2000, Volume: 12, Issue:5-6

    Topics: Chemistry; Cinnamates; Cyclohexanes; Cyclopentanes; Furans; Hydrocarbons; Models, Chemical; Molecular Conformation; Pyrroles; Stereoisomerism

2000
Kinetic resolution and isomerization of 2,5-disubstituted pyrrolines.
    Chirality, 2000, Volume: 12, Issue:5-6

    Topics: Chemistry; Imines; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Pyrroles; Stereoisomerism; Temperature

2000
A convergent approach to the mitomycin ring system.
    Organic letters, 2001, Apr-19, Volume: 3, Issue:8

    Topics: Alkylating Agents; Magnetic Resonance Spectroscopy; Mitomycin; Models, Chemical; Models, Molecular; Pyrroles

2001
A convenient method for 3-pyrroline synthesis.
    Organic letters, 2001, Oct-18, Volume: 3, Issue:21

    Topics: Acetylcysteine; Alkylation; Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Cyclization; Lactams; Pyrroles; Stereoisomerism

2001
Synthesis of 3-pyrrolines, annulated 3-pyrrolines, and pyrroles from alpha-amino allenes.
    Organic letters, 2001, Nov-29, Volume: 3, Issue:24

    Topics: Pyrroles

2001
3-Pyrroline containing arylacetamides: a novel series of remarkably selective kappa-agonists.
    Bioorganic & medicinal chemistry letters, 2002, Sep-02, Volume: 12, Issue:17

    Topics: Acetamides; Analgesics, Opioid; Animals; Humans; Injections, Intraperitoneal; Pain; Pyrroles; Radioligand Assay; Rats; Receptors, Opioid, kappa; Structure-Activity Relationship

2002
Total synthesis of the alkaloids martinelline and martinellic acid via a hetero Diels-Alder multicomponent coupling reaction.
    Organic letters, 2002, Aug-22, Volume: 4, Issue:17

    Topics: 4-Aminobenzoic Acid; Alkaloids; Anti-Bacterial Agents; Bradykinin Receptor Antagonists; Guanidine; para-Aminobenzoates; Pyrroles; Quinolines

2002
3-pyrrolines are mechanism-based inactivators of the quinone-dependent amine oxidases but only substrates of the flavin-dependent amine oxidases.
    Journal of the American Chemical Society, 2002, Oct-16, Volume: 124, Issue:41

    Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; Enzyme Activation; Enzyme Inhibitors; Kinetics; Mitochondria, Liver; Monoamine Oxidase; Pyrroles; Pyrrolidines; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity

2002
Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modulating activity.
    Journal of agricultural and food chemistry, 2002, Nov-20, Volume: 50, Issue:24

    Topics: Antioxidants; Bread; Caco-2 Cells; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Malondialdehyde; NADPH-Ferrihemoprotein Reductase; Polymers; Proteins; Pyrroles

2002
A stereoselective and short total synthesis of the polyhydroxylated gamma-amino acid (-)-detoxinine, based on stereoselective preparation of dihydropyrrole derivatives from lithiated alkoxyallenes.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2003, Mar-17, Volume: 9, Issue:6

    Topics: Alkanes; Lithium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Pyrroles; Stereoisomerism

2003
The nitroxides pirolin and pirolid protect the plasma membranes of rat cardiomyocytes against damage induced by anthracyclines.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:1

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Cell Membrane; Cyclic N-Oxides; Doxorubicin; Fluorescence Polarization; Fluorescent Dyes; In Vitro Techniques; Male; Membrane Fluidity; Myocytes, Cardiac; Nitrogen Oxides; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Stearic Acids

2003
Effects of pyrroline and pyrrolidine nitroxides on lipid peroxidation in heart tissue of rats treated with doxorubicin.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Heart; Lipid Peroxidation; Malondialdehyde; Myocardium; Nitrogen Oxides; Pyrroles; Pyrrolidines; Rats; Rats, Wistar

2003
Cyclooxygenase-1/2 (COX-1/COX-2) and 5-lipoxygenase (5-LOX) inhibitors of the 6,7-diaryl-2,3-1H-dihydropyrrolizine type.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:12

    Topics: Animals; Blood Platelets; Cattle; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Drug Design; Enzyme Inhibitors; Humans; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Pyrroles; Radioimmunoassay

2002
Highly selective catalyst-directed pathways to dihydropyrroles from vinyldiazoacetates and imines.
    Journal of the American Chemical Society, 2003, Apr-23, Volume: 125, Issue:16

    Topics: Acetates; Catalysis; Copper; Imines; Magnetic Resonance Spectroscopy; Pyrroles; Rhodium; Vinyl Compounds

2003
Synthesis and insecticidal activity of novel N-oxydihydropyrrole derivatives with a substituted spirocyclohexyl group.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:6

    Topics: Animals; Aphids; Cyclohexanes; Insecticides; Pyrroles; Spiro Compounds; Structure-Activity Relationship

2003
The interconversion of glutamic acid and proline. I. The formation of delta1-pyrroline-5-carboxylic acid from glutamic acid in Escherichia coli.
    The Journal of biological chemistry, 1957, Volume: 225, Issue:2

    Topics: Carboxylic Acids; Escherichia coli; Glutamates; Glutamic Acid; Proline; Pyrroles

1957
Hydroxyproline metabolism. II. Enzymatic preparation and properties of Delta 1-pyrroline-3-hydroxy-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. III. Enzymatic synthesis of hydroxyproline from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Amino Acids; Glutamates; Hydroxyproline; Proline; Pyrroles

1960
The interconversion of glutamic acid and proline. II. The preparation and properties of delta 1-pyrroline-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1960
[Oxydation of proline by periodate and isolation of 1-pyrroline].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1959, Volume: 14B

    Topics: Oxidation-Reduction; Periodic Acid; Proline; Pyrroles

1959
Formation of pyrroline and propane diamine from spermidine by extracts of Serratia marcescens.
    Nature, 1962, Apr-28, Volume: 194

    Topics: Amines; Diamines; Propane; Pyrroles; Serratia marcescens; Spermidine

1962
[ON THE EFFECT, UTILIZATION AND METABOLISM OF 5-AMINO-2-OXOVALERIC ACID (DELTA-1-PYRROLINE-2-CARBOXYLIC ACID)IN PEA SEEDS AND BAKER'S YEASTS].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1965, Volume: 340

    Topics: Amino Acids; Carboxylic Acids; Keto Acids; Metabolism; Pisum sativum; Pyrroles; Research; Saccharomyces; Saccharomyces cerevisiae; Seeds

1965
[Photometric determination of alpha-keto-delta-aminovaleric acid (delta1-pyrroline-2-carboxylic acid) and prolines].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1962, Aug-06, Volume: 328

    Topics: Amino Acids; Amino Acids, Neutral; Carboxylic Acids; Proline; Pyrroles; Valine

1962
The interconversion of glutamic acid and proline. V. The reduction of delta 1-pyrroline-5-carboxylic acid to proline.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1962
Highly regio- and enantioselective Heck reaction of N-methoxycarbonyl-2-pyrroline with planar chiral diphosphine-oxazoline ferrocenyl ligands.
    Organic letters, 2003, Oct-02, Volume: 5, Issue:20

    Topics: Ferrous Compounds; Ligands; Metallocenes; Oxazoles; Palladium; Phosphines; Pyrroles; Stereoisomerism

2003
Esters of 5-carboxyl-5-methyl-1-pyrroline N-oxide: a family of spin traps for superoxide.
    The Journal of organic chemistry, 2003, Oct-03, Volume: 68, Issue:20

    Topics: Binding, Competitive; Cyclic N-Oxides; Cytochromes c; Electron Spin Resonance Spectroscopy; Esters; Half-Life; Hydrogen-Ion Concentration; Kinetics; Pyrroles; Spin Labels; Spin Trapping; Superoxides; Xanthine; Xanthine Oxidase

2003
A novel approach to the synthesis of cytotoxic C2-C3 unsaturated pyrrolo[2,1-c]benzodiazepines (PBDs) with conjugated acrylyl C2-substituents.
    Bioorganic & medicinal chemistry letters, 2004, Mar-22, Volume: 14, Issue:6

    Topics: Benzodiazepines; Cell Line, Tumor; Humans; Pyrroles

2004
Microximetry: simultaneous determination of oxygen consumption and free radical production using electron paramagnetic resonance spectroscopy.
    Methods in enzymology, 2004, Volume: 381

    Topics: Animals; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Indoles; Molecular Probes; Organometallic Compounds; Oxygen; Oxygen Consumption; Pyrroles; Superoxides; Xanthine; Xanthine Oxidase

2004
Design and photochemical characterization of a biomimetic light-driven Z/E switcher.
    Journal of the American Chemical Society, 2004, Aug-04, Volume: 126, Issue:30

    Topics: Biomimetic Materials; Cyclopentanes; Imines; Isomerism; Models, Molecular; Molecular Conformation; Photochemistry; Pyrroles; Rhodopsin; Schiff Bases; Thermodynamics

2004
Dissociation between urinary pyrraline and pentosidine concentrations in diabetic patients with advanced nephropathy.
    The Journal of laboratory and clinical medicine, 2004, Volume: 144, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; beta 2-Microglobulin; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Lysine; Pyrroles; Reference Values; Regression Analysis

2004
Novel pyrrolinones as N-methyl-D-aspartate receptor antagonists.
    European journal of medicinal chemistry, 2005, Volume: 40, Issue:4

    Topics: Binding Sites; Glycine; Molecular Structure; Pyrroles; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2005
Very stable superoxide radical adducts of 5-ethoxycarbonyl- 3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives.
    Biochemical pharmacology, 2005, May-01, Volume: 69, Issue:9

    Topics: Carbon Isotopes; Cyclic N-Oxides; Drug Stability; Electron Spin Resonance Spectroscopy; Free Radicals; Half-Life; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Protons; Pyrroles; Spin Labels; Spin Trapping; Stereoisomerism; Superoxides

2005
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.
    Cancer cell, 2005, Volume: 8, Issue:1

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Cycle Proteins; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; Genes, cdc; HeLa Cells; Humans; Kinesins; Mitosis; Molecular Structure; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Spindle Apparatus

2005
Nitrosation chemistry of pyrroline, 2-imidazoline, and 2-oxazoline: theoretical Curtin-Hammett analysis of retro-ene and solvent-assisted C-X cleavage reactions of alpha-hydroxy-N-nitrosamines.
    The Journal of organic chemistry, 2005, Aug-19, Volume: 70, Issue:17

    Topics: Hydrolysis; Imidazoles; Nitrosamines; Nitrosation; Oxazoles; Pyrroles; Solvents

2005
Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues.
    Journal of agricultural and food chemistry, 2005, Oct-19, Volume: 53, Issue:21

    Topics: Animals; Cattle; Electron Transport; Electron Transport Complex I; Enzyme Inhibitors; Mitochondria, Heart; Oximes; Penicillium; Pyrroles

2005
A formal synthesis of (+)-lactacystin.
    Chemical communications (Cambridge, England), 2005, Oct-28, Issue:40

    Topics: Acetylcysteine; Alkylation; Hydrocarbons; Methane; Molecular Structure; Pyrroles

2005
Tandem photocycloaddition-retro-mannich fragmentation of enaminones. A route to spiropyrrolines and the tetracyclic core of koumine.
    Organic letters, 2006, Mar-16, Volume: 8, Issue:6

    Topics: Amides; Catalysis; Cyclization; Indole Alkaloids; Molecular Structure; Photochemistry; Pyrroles; Spiro Compounds; Stereoisomerism

2006
Spin trapping by 5,5-dimethylpyrroline-N-oxide in Fenton media in the presence of Nafion perfluorinated membranes: limitations and potential.
    The journal of physical chemistry. B, 2006, Jun-08, Volume: 110, Issue:22

    Topics: Electron Spin Resonance Spectroscopy; Fluorine; Fluorocarbon Polymers; Membranes, Artificial; Pyrroles; Spin Labels

2006
Total syntheses of (+/-)-cis-trikentrin A and (+/-)-cis-trikentrin B via electrocyclic ring closures of 2,3-divinylpyrrolines.
    Organic letters, 2006, Jul-20, Volume: 8, Issue:15

    Topics: Animals; Cyclization; Indole Alkaloids; Molecular Structure; Porifera; Pyrroles; Stereoisomerism

2006
Effects of anion proximity in peptide primary sequence on the rate and mechanism of leucine oxidation.
    Analytical chemistry, 2006, Jul-15, Volume: 78, Issue:14

    Topics: Amino Acid Sequence; Anions; Free Radicals; Leucine; Mass Spectrometry; Molecular Structure; Molecular Weight; Oxidation-Reduction; Peptides; Pyrroles

2006
An enzymatic approach to the desymmetrization of disubstituted pyrrolines.
    The Journal of organic chemistry, 2006, Aug-04, Volume: 71, Issue:16

    Topics: Lipase; Molecular Structure; Pseudomonas; Pyrroles; Stereoisomerism

2006
Advanced glycation end product deposits in climatic droplet keratopathy.
    The British journal of ophthalmology, 2007, Volume: 91, Issue:1

    Topics: Antibodies, Monoclonal; Arginine; Cornea; Corneal Diseases; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Pyrroles

2007
Highly potent 3-pyrroline mechanism-based inhibitors of bovine plasma amine oxidase and mass spectrometric confirmation of cofactor derivatization.
    Bioorganic & medicinal chemistry, 2007, Feb-15, Volume: 15, Issue:4

    Topics: Amine Oxidase (Copper-Containing); Animals; Binding Sites; Cattle; Mass Spectrometry; Pyrroles

2007
Microwave-assisted preparations of dihydropyrroles from alkenone O-phenyl oximes.
    Chemical communications (Cambridge, England), 2007, Oct-21, Issue:39

    Topics: Alkanes; Free Radicals; Hydrogen; Microwaves; Molecular Structure; Oximes; Pyrroles

2007
Copper-catalyzed multicomponent reaction: facile access to functionalized 5-arylidene-2-imino-3-pyrrolines.
    Organic letters, 2007, Nov-22, Volume: 9, Issue:24

    Topics: Alkynes; Azides; Catalysis; Copper; Iodides; Molecular Structure; Pyrroles

2007
Use of polyvinylpyrrolidone in the clinic; polyvinylpyrrolidone in anemias.
    Rivista di patologia e clinica, 1949, Volume: 4, Issue:2

    Topics: Anemia; Pyrroles

1949
Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines.
    Bioorganic & medicinal chemistry letters, 2008, Feb-15, Volume: 18, Issue:4

    Topics: Acetophenones; Aldehydes; Antineoplastic Agents; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isomerism; Jurkat Cells; Nitriles; Pyrroles; Structure-Activity Relationship

2008
Organocatalytic asymmetric formal [3+2] cycloaddition reaction of isocyanoesters to nitroolefins leading to highly optically active dihydropyrroles.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:18

    Topics: Catalysis; Cinchona Alkaloids; Cyanides; Esters; Lithium Compounds; Optics and Photonics; Organometallic Compounds; Pyrroles; Stereoisomerism

2008
Deconstructing cytisine: The syntheses of (+/-)-cyfusine and (+/-)-cyclopropylcyfusine, fused ring analogs of cytisine.
    Bioorganic & medicinal chemistry letters, 2008, Apr-01, Volume: 18, Issue:7

    Topics: Alkaloids; Azocines; Cyclization; Cyclopropanes; Heterocyclic Compounds, 3-Ring; Models, Chemical; Pyridones; Pyrroles; Quinolizines; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2008
Diverse reactions of 1,4-dilithio-1,3-dienes with nitriles: facile access to tricyclic Delta1-bipyrrolines, multiply substituted pyridines, siloles, and (Z,Z)-dienylsilanes by tuning of substituents on the butadienyl skeleton.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:18

    Topics: Magnetic Resonance Spectroscopy; Models, Molecular; Nitriles; Pyridines; Pyrroles; Silanes; Sulfhydryl Compounds

2008
5-phenyl-3,4-dihydro-2H-pyrrole: the first example of a planar monosubstituted 1-pyrroline.
    Acta crystallographica. Section C, Crystal structure communications, 2008, Volume: 64, Issue:Pt 6

    Topics: Dimerization; Molecular Conformation; Molecular Structure; Pyrroles; X-Ray Diffraction

2008
Toward the synthesis of cobyric acid. Enantioselective syntheses of completely differentiated ring D synthons.
    Organic letters, 2008, Jul-03, Volume: 10, Issue:13

    Topics: Acids; Molecular Structure; Pyrroles; Stereoisomerism; Vitamin B 12

2008
From dioxime oxalates to dihydropyrroles and phenanthridines via iminyl radicals.
    Chemical communications (Cambridge, England), 2008, Sep-21, Issue:35

    Topics: Electron Spin Resonance Spectroscopy; Free Radicals; Imines; Oxalates; Phenanthridines; Pyrroles

2008
Lewis acid catalyzed [1,3]-sigmatropic rearrangement of vinyl aziridines.
    Organic letters, 2008, Nov-06, Volume: 10, Issue:21

    Topics: Acids; Aziridines; Catalysis; Copper; Kinetics; Molecular Structure; Pyrroles; Vinyl Compounds

2008
beta-Cycloylpropionitriles; reduction to 2-cyclyl-delta2-pyrrolines and 2-cyclylpyrrolidines.
    Journal of the Chemical Society, 1948

    Topics: Nitriles; Pyrroles

1948
Synthesis of (+)-DGDP and (-)-7-epialexine.
    Organic & biomolecular chemistry, 2008, Nov-07, Volume: 6, Issue:21

    Topics: Pyrroles; Pyrrolizidine Alkaloids; Sorbitol; Stereoisomerism

2008
A commonly used spin label: S-(2,2,5,5-tetramethyl-1-oxyl-delta3-pyrrolin-3-ylmethyl) methanethiosulfonate.
    Acta crystallographica. Section C, Crystal structure communications, 2008, Volume: 64, Issue:Pt 11

    Topics: Crystallization; Crystallography; Mesylates; Models, Molecular; Molecular Conformation; Pyrroles; Spin Labels

2008
Rearrangement of N-aryl-2-vinylaziridines to benzoazepines and dihydropyrroles: a synthetic and theoretical study.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Volume: 15, Issue:5

    Topics: Azides; Heterocyclic Compounds; Isomerism; Models, Chemical; Molecular Conformation; Pyrroles

2009
One-pot three-component tandem reaction of diazo compounds with anilines and unsaturated ketoesters: a novel synthesis of 2,3-dihydropyrrole derivatives.
    Chemical communications (Cambridge, England), 2009, Mar-21, Issue:11

    Topics: Aniline Compounds; Azo Compounds; Esters; Ketones; Molecular Structure; Pyrroles

2009
Synthesis of alpha-cyclopropyl-beta-homoprolines.
    The Journal of organic chemistry, 2009, Jun-05, Volume: 74, Issue:11

    Topics: Amino Acids, Cyclic; Oligopeptides; Proline; Pyrroles; Stereoisomerism

2009
Fluorenylidene-pyrroline biomimetic light-driven molecular switches.
    The Journal of organic chemistry, 2009, Jul-03, Volume: 74, Issue:13

    Topics: Alkylation; Biomimetic Materials; Crystallography, X-Ray; Fluorenes; Light; Magnetic Resonance Spectroscopy; Photochemistry; Pyrroles; Stereoisomerism

2009
Synthesis of substituted pyrrolin-4-ones from amino acids in mild conditions via a gold-catalyzed approach.
    The Journal of organic chemistry, 2009, Aug-07, Volume: 74, Issue:15

    Topics: Amino Acids; Catalysis; Gold; Molecular Conformation; Pyrroles; Stereoisomerism

2009
Overhauser dynamic nuclear polarization and molecular dynamics simulations using pyrroline and piperidine ring nitroxide radicals.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2009, Volume: 200, Issue:1

    Topics: Computer Simulation; Electron Spin Resonance Spectroscopy; Free Radicals; Indicators and Reagents; Models, Molecular; Nitrogen Oxides; Piperidines; Protons; Pyrroles; Reactive Nitrogen Species; Spin Labels; Water

2009
Facile construction of highly functionalized 2-pyrrolines via FeCl(3)-catalyzed reaction of aziridines with arylalkynes.
    Chemical communications (Cambridge, England), 2009, Sep-07, Issue:33

    Topics: Alkynes; Aziridines; Catalysis; Chlorides; Cyclization; Ferric Compounds; Pyrroles

2009
2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities.
    Biochemical pharmacology, 2010, Feb-15, Volume: 79, Issue:4

    Topics: Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Drugs, Investigational; Hypoglycemic Agents; Indans; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mice, Transgenic; Pyrroles

2010
Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Humans; Niemann-Pick Disease, Type C; Pyrroles

2009
Allenyl sulfones and allenyl sulfides in the synthesis of 3-pyrrolines. A novel nucleophilic [3 + 2] cycloaddition on allenyl sulfones giving rearranged cycloadducts.
    Organic letters, 2009, Nov-05, Volume: 11, Issue:21

    Topics: Catalysis; Cyclization; Imines; Molecular Structure; Pheromones; Pyrroles; Stereoisomerism; Sulfides; Sulfones

2009
Formation of N-alkylpyrroles via intermolecular redox amination.
    Journal of the American Chemical Society, 2009, Nov-25, Volume: 131, Issue:46

    Topics: Aldehydes; Amination; Isomerism; Ketones; Lactones; Oxidation-Reduction; Pyrroles

2009
Mild and efficient desymmetrization of diynes via hydroamination: application to the synthesis of (+/-)-monomorine I.
    The Journal of organic chemistry, 2010, Feb-19, Volume: 75, Issue:4

    Topics: Amination; Catalysis; Diynes; Indolizines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pyrroles; Silver; Stereoisomerism

2010
Relation between the pyridic and pyrrolic nuclei.
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1947, Feb-17, Volume: 224, Issue:7

    Topics: Pyridines; Pyrroles

1947
Tuning electronic and steric effects: highly enantioselective [4+1] pyrroline annulation of sulfur ylides with alpha,beta-unsaturated imines.
    Angewandte Chemie (International ed. in English), 2010, Jun-14, Volume: 49, Issue:26

    Topics: Crystallography, X-Ray; Cyclization; Electrons; Imines; Molecular Conformation; Pyrroles; Stereoisomerism; Sulfur

2010
Synthesis of 3-aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole derivatives: a comparison between conventional, microwave-assisted and flow-based methodologies.
    The Journal of organic chemistry, 2010, Nov-05, Volume: 75, Issue:21

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Isoxazoles; Microwaves; Nitriles; Pyrroles

2010
Synthesis and characterization of 5-hydroxymethyl-5-methyl-pyrroline N-oxide and its derivatives.
    Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2

    Topics: Cyclic N-Oxides; Hydroxyl Radical; Methane; Pyrroles; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared

2011
Stereospecific ring expansion of chiral vinyl aziridines.
    Organic letters, 2011, Mar-04, Volume: 13, Issue:5

    Topics: Aziridines; Combinatorial Chemistry Techniques; Cyclization; Molecular Structure; Pyrroles; Stereoisomerism; Vinyl Compounds

2011
An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis.
    Organic & biomolecular chemistry, 2011, Apr-07, Volume: 9, Issue:7

    Topics: Amines; Catalysis; Molecular Structure; Palladium; Pyrroles; Transition Elements

2011
Phosphine-catalyzed [4 + 1] annulation between α,β-unsaturated imines and allylic carbonates: synthesis of 2-pyrrolines.
    The Journal of organic chemistry, 2011, Apr-01, Volume: 76, Issue:7

    Topics: Carbonates; Catalysis; Cyclization; Imines; Molecular Structure; Phosphines; Pyrroles; Stereoisomerism

2011
Synthesis and photophysical characterization of stable indium bacteriochlorins.
    Inorganic chemistry, 2011, May-16, Volume: 50, Issue:10

    Topics: Acids; Bacteria; Bacteriochlorophylls; Catalysis; Coordination Complexes; Electrons; Fluorescence; Indium; Kinetics; Light; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Mimicry; Photochemistry; Photochemotherapy; Porphyrins; Pyrroles; Quantum Theory

2011
Site-specific protein modifications through pyrroline-carboxy-lysine residues.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jun-28, Volume: 108, Issue:26

    Topics: Culture Media; Escherichia coli; Lysine; Nuclear Magnetic Resonance, Biomolecular; Proteins; Pyrroles

2011
Pyrrolinone-pyrrolidine oligomers as universal peptidomimetics.
    Journal of the American Chemical Society, 2011, Aug-17, Volume: 133, Issue:32

    Topics: Models, Molecular; Peptidomimetics; Protein Structure, Secondary; Pyrroles; Pyrrolidines

2011
Cis-trans photoisomerization properties of GFP chromophore analogs.
    European biophysics journal : EBJ, 2011, Volume: 40, Issue:11

    Topics: 4-Butyrolactone; Color; Green Fluorescent Proteins; Magnetic Resonance Spectroscopy; Optical Phenomena; Photochemical Processes; Pyrroles; Stereoisomerism

2011
A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:9

    Topics: Alkaloids; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Piper; Plant Roots; Plant Stems; Pyrroles

2011
Purification and characterization of a novel (R)-imine reductase from Streptomyces sp. GF3587.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:9

    Topics: Chromatography, Gel; Dimerization; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Imines; Kinetics; Methylation; Molecular Weight; NADP; Oxidoreductases; p-Chloromercuribenzoic Acid; Protein Subunits; Pyrroles; Pyrrolidines; Streptomyces; Substrate Specificity; Sulfhydryl Reagents

2011
Lewis acid-catalyzed [3 + 2]cyclo-addition of alkynes with N-tosyl-aziridines via carbon-carbon bond cleavage: synthesis of highly substituted 3-pyrrolines.
    Organic letters, 2011, Nov-18, Volume: 13, Issue:22

    Topics: Alkynes; Aziridines; Carbon; Catalysis; Cyclization; Lewis Acids; Molecular Structure; Pyrroles; Stereoisomerism

2011
Immobilization of antibacterial dihydropyrrol-2-ones on functional polymer supports to prevent bacterial infections in vivo.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Acrylic Resins; Animals; Anti-Bacterial Agents; Humans; Male; Mice; Microspheres; Polymers; Prosthesis-Related Infections; Pyrroles; Staphylococcal Skin Infections; Staphylococcus aureus

2012
Versatile enantioselective [3+2] cyclization between imines and allenoates catalyzed by dipeptide-based phosphines.
    Angewandte Chemie (International ed. in English), 2012, Jan-16, Volume: 51, Issue:3

    Topics: Alkadienes; Catalysis; Cyclization; Dipeptides; Imines; Phosphines; Pyrroles; Pyrrolizidine Alkaloids

2012
3D-QSAR studies of dihydropyrazole and dihydropyrrole derivatives as inhibitors of human mitotic kinesin Eg5 based on molecular docking.
    Molecules (Basel, Switzerland), 2012, Feb-17, Volume: 17, Issue:2

    Topics: Binding Sites; Humans; Kinesins; Ligands; Mitosis; Models, Molecular; Protein Binding; Pyrroles; Quantitative Structure-Activity Relationship

2012
Catalytic enantioselective synthesis of β-trifluoromethyl pyrrolines.
    Chemical communications (Cambridge, England), 2012, Apr-28, Volume: 48, Issue:34

    Topics: Catalysis; Cyclization; Hydrocarbons, Fluorinated; Oxidation-Reduction; Pyrroles; Stereoisomerism

2012
Effect of timing and duration of salt treatment during growth of a fragrant rice variety on yield and 2-acetyl-1-pyrroline, proline, and GABA Levels.
    Journal of agricultural and food chemistry, 2012, Apr-18, Volume: 60, Issue:15

    Topics: gamma-Aminobutyric Acid; Oryza; Pyrroles; Sodium Chloride; Time Factors

2012
DBU-catalyzed tandem additions of electron-deficient 1,3-conjugated enynes with 2-aminomalonates: a facile access to highly substituted 2-pyrrolines.
    Chemical communications (Cambridge, England), 2012, Apr-25, Volume: 48, Issue:33

    Topics: Alkenes; Alkynes; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Electrons; Malonates; Pyrroles

2012
Organocatalytic asymmetric synthesis of trifluoromethyl-substituted diarylpyrrolines: enantioselective conjugate cyanation of β-aryl-β-trifluoromethyl-disubstituted enones.
    Angewandte Chemie (International ed. in English), 2012, May-14, Volume: 51, Issue:20

    Topics: Catalysis; Crystallography, X-Ray; Cyanates; Hydrocarbons, Fluorinated; Isoxazoles; Molecular Structure; Pyrroles; Stereoisomerism

2012
Reversible photocontrol of peptide conformation with a rhodopsin-like photoswitch.
    Journal of the American Chemical Society, 2012, Apr-25, Volume: 134, Issue:16

    Topics: Benzylidene Compounds; Molecular Structure; Peptides; Photochemical Processes; Protein Conformation; Pyrroles; Rhodopsin; Schiff Bases

2012
Phosphine-catalyzed intramolecular γ-umpolung addition of α-aminoalkylallenic esters: facile synthesis of 3-carbethoxy-2-alkyl-3-pyrrolines.
    Chemical communications (Cambridge, England), 2012, May-28, Volume: 48, Issue:43

    Topics: Amines; Catalysis; Esters; Isomerism; Phosphines; Piperazines; Pyrroles

2012
A novel class of small-molecule caspase-3 inhibitors prepared by multicomponent reactions.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Caspase 3; Caspase Inhibitors; Chemistry Techniques, Synthetic; Humans; Inhibitory Concentration 50; Pyrroles; Structure-Activity Relationship

2012
A facile and ecofriendly functionalization of multiwalled carbon nanotubes by an old mesoionic compound.
    Chemical communications (Cambridge, England), 2012, Jul-11, Volume: 48, Issue:54

    Topics: Azo Compounds; Fullerenes; Nanotubes, Carbon; Oxazolone; Pyrroles; Spectrum Analysis, Raman; Thiosemicarbazones

2012
Synthesis of 2,5-bis(spirocyclohexane)-substituted nitroxides of pyrroline and pyrrolidine series, including thiol-specific spin label: an analogue of MTSSL with long relaxation time.
    The Journal of organic chemistry, 2012, Sep-21, Volume: 77, Issue:18

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mesylates; Molecular Structure; Nitric Oxide; Pyrroles; Pyrrolidines; Spin Labels; Spiro Compounds; Sulfhydryl Compounds

2012
Enantioselective organocatalytic one-pot amination/aza-Michael/aldol condensation reaction sequence: synthesis of 3-pyrrolines with a quaternary stereocenter.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Oct-08, Volume: 18, Issue:41

    Topics: Aldehydes; Amination; Amines; Catalysis; Hydrazines; Molecular Structure; Pyrroles; Stereoisomerism

2012
Rapid synthesis of substituted pyrrolines and pyrrolidines by nucleophilic ring closure at activated oximes.
    Organic & biomolecular chemistry, 2012, Oct-21, Volume: 10, Issue:39

    Topics: Molecular Structure; Oximes; Pyrroles; Pyrrolidines; Stereoisomerism

2012
Synthesis of 4-hydroxy-β3-homoprolines and their insertion in α/β/α-tripeptides.
    Amino acids, 2013, Volume: 44, Issue:2

    Topics: Molecular Structure; Oligopeptides; Proline; Pyrroles; Stereoisomerism

2013
Mechanistic origin of the vibrational coherence accompanying the photoreaction of biomimetic molecular switches.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Nov-26, Volume: 18, Issue:48

    Topics: Indans; Isomerism; Molecular Structure; Photochemical Processes; Pyrroles; Rhodopsin; Spectrum Analysis; Time Factors; Vibration

2012
Synthesis and potential use of 1,8-naphthalimide type (1)O2 sensor molecules.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:3

    Topics: Amines; Anhydrides; Chemistry Techniques, Analytical; Chemistry Techniques, Synthetic; Fluorescent Dyes; Imides; Naphthalenes; Nicotiana; Plant Leaves; Pyrroles; Singlet Oxygen

2013
Pyrrole- and dihydropyrrole-fused neonicotinoids: design, synthesis, and insecticidal evaluation.
    Journal of agricultural and food chemistry, 2013, Jan-16, Volume: 61, Issue:2

    Topics: Anabasine; Animals; Aphids; Drug Design; Insecticides; Lethal Dose 50; Molecular Structure; Pyrroles; Structure-Activity Relationship

2013
Development of four-component synthesis of tetra- and pentasubstituted polyfunctional dihydropyrroles: free permutation and combination of aromatic and aliphatic amines.
    ACS combinatorial science, 2013, Apr-08, Volume: 15, Issue:4

    Topics: Amines; Benzaldehydes; Catalysis; Combinatorial Chemistry Techniques; Copper; Hydrocarbons, Aromatic; Lewis Acids; Oxidation-Reduction; Pyrroles

2013
Dual behavior of isatin-based cyclic ketimines with dicarbomethoxy carbene: expedient synthesis of highly functionalized spirooxindolyl oxazolidines and pyrrolines.
    Organic letters, 2013, Apr-05, Volume: 15, Issue:7

    Topics: Azo Compounds; Crystallography, X-Ray; Cycloaddition Reaction; Imines; Indoles; Isatin; Molecular Structure; Nitriles; Oxazoles; Pyrroles; Spiro Compounds; Stereoisomerism; Thiosemicarbazones

2013
Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil.
    Experimental oncology, 2013, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Intestinal Mucosa; Male; Pyrroles; Pyrrolidinones; Rats; Rats, Wistar

2013
Structural equilibrium in new nitroxide-capped cyclodextrins: CW and pulse EPR study.
    The journal of physical chemistry. B, 2013, Jul-11, Volume: 117, Issue:27

    Topics: Cyclodextrins; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Nitrogen Oxides; Piperidines; Pyrroles; Pyrrolidines; Spin Labels

2013
A new pyrroline compound selective for I1-imidazoline receptors improves metabolic syndrome in rats.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 346, Issue:3

    Topics: 3T3-L1 Cells; Adiponectin; Aniline Compounds; Animals; Blood Pressure; Body Weight; Glucose Intolerance; Glucose Tolerance Test; Imidazoline Receptors; Insulin Resistance; Kidney; Lipids; Male; Metabolic Syndrome; Mice; Pyrroles; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Surface Plasmon Resonance; Sympathetic Nervous System

2013
Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists.
    Bioorganic & medicinal chemistry, 2013, Oct-01, Volume: 21, Issue:19

    Topics: Animals; Benzofurans; Benzoxazines; Chlorocebus aethiops; COS Cells; Crystallography, X-Ray; Drug Design; Inhibitory Concentration 50; Mineralocorticoid Receptor Antagonists; Protein Binding; Pyrroles; Structure-Activity Relationship

2013
TfOH-catalyzed formal [3 + 2] cycloaddition of cyclopropane 1,1-diesters with nitriles.
    The Journal of organic chemistry, 2014, Jan-17, Volume: 79, Issue:2

    Topics: Catalysis; Cyclization; Cyclopropanes; Esters; Mesylates; Molecular Structure; Nitriles; Pyrroles

2014
Design, synthesis and pharmacological evaluation of novel pyrrolizine derivatives as potential anticancer agents.
    Bioorganic chemistry, 2014, Volume: 53

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drug Design; Humans; MCF-7 Cells; Pyrroles

2014
Short total synthesis of (-)-kainic acid.
    Organic letters, 2014, May-02, Volume: 16, Issue:9

    Topics: Catalysis; Copper; Kainic Acid; Molecular Structure; Oxidation-Reduction; Pyrroles; Stereoisomerism

2014
The formation of pyrroline and tetrahydropyridine rings in amino acids catalyzed by pyrrolysine synthase (PylD).
    Angewandte Chemie (International ed. in English), 2014, Jul-28, Volume: 53, Issue:31

    Topics: Catalysis; Catalytic Domain; Ligases; Lysine; Pyridines; Pyrroles

2014
Methyl-methoxylpyrrolinone and flavinium nucleus binding signatures on falcipain-2 active site.
    Journal of molecular modeling, 2014, Volume: 20, Issue:8

    Topics: Antimicrobial Cationic Peptides; Catalytic Domain; Cysteine Endopeptidases; Flavins; Flavonoids; Flavonols; Ligands; Molecular Dynamics Simulation; Peptides; Protease Inhibitors; Protons; Pyrroles; Thermodynamics

2014
Hydroxyproline-derived pseudoenantiomeric [2.2.1] bicyclic phosphines: asymmetric synthesis of (+)- and (-)-pyrrolines.
    Journal of the American Chemical Society, 2014, Aug-27, Volume: 136, Issue:34

    Topics: Bridged Bicyclo Compounds; Hydroxyproline; Molecular Structure; Phosphines; Pyrroles; Stereoisomerism

2014
Initial excited-state dynamics of an N-alkylated indanylidene-pyrroline (NAIP) rhodopsin analog.
    The journal of physical chemistry. B, 2014, Oct-23, Volume: 118, Issue:42

    Topics: Alkylation; Indans; Models, Molecular; Molecular Conformation; Pyrroles; Rhodopsin; Spectrum Analysis, Raman; Stereoisomerism

2014
Synthesis of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides.
    Organic letters, 2014, Oct-17, Volume: 16, Issue:20

    Topics: Amino Acids; Ascorbic Acid; Cyclic N-Oxides; Cysteine; Glutathione; Molecular Structure; Oxidation-Reduction; Pyrroles; Pyrrolidines; Stereoisomerism

2014
One-pot synthesis of 2,5-dihydropyrroles from terminal alkynes, azides, and propargylic alcohols by relay actions of copper, rhodium, and gold.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Dec-01, Volume: 20, Issue:49

    Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Gold; Propanols; Pyrroles; Rhodium; Triazoles

2014
Intramolecular redox reaction for the synthesis of N-aryl pyrroles catalyzed by Lewis acids.
    Organic & biomolecular chemistry, 2014, Dec-21, Volume: 12, Issue:47

    Topics: Aldehydes; Catalysis; Cyclization; Heterocyclic Compounds, 3-Ring; Isomerism; Lewis Acids; Oxidation-Reduction; Pyrroles

2014
Asymmetric synthesis of 2,3-dihydropyrroles by ring-opening/cyclization of cyclopropyl ketones using primary amines.
    Angewandte Chemie (International ed. in English), 2015, Jan-02, Volume: 54, Issue:1

    Topics: Amines; Catalysis; Cyclization; Ketones; Oxides; Pyrroles; Scandium

2015
Formal [3+2] cycloaddition of Ugi adducts towards pyrrolines.
    Chemical communications (Cambridge, England), 2015, Jan-21, Volume: 51, Issue:6

    Topics: Amides; Cyclization; Cycloaddition Reaction; Microwaves; Molecular Structure; Pyrroles

2015
Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycin.
    Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3

    Topics: Aminoglycosides; Anthramycin; Dioxygenases; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrroles

2015
Enantioselective rhodium-catalyzed isomerization of 4-iminocrotonates: asymmetric synthesis of a unique chiral synthon.
    Journal of the American Chemical Society, 2015, Jan-21, Volume: 137, Issue:2

    Topics: Catalysis; Chemistry Techniques, Synthetic; Crotonates; Cyclization; Pyrroles; Rhodium; Stereoisomerism; Substrate Specificity

2015
2,2- and 2,6-Diarylpiperidines by aryl migration within lithiated urea derivatives of tetrahydropyridines.
    Organic letters, 2015, Mar-06, Volume: 17, Issue:5

    Topics: Cyclization; Lithium; Molecular Structure; Piperidines; Pyridines; Pyrroles; Urea

2015
Phosphine-Catalyzed Aza-MBH Reactions of Vinylpyridines: Efficient and Rapid Access to 2,3,5-Triarylsubstituted 3-Pyrrolines.
    Organic letters, 2015, May-01, Volume: 17, Issue:9

    Topics: Catalysis; Molecular Structure; Phosphines; Pyrroles; Stereoisomerism; Vinyl Compounds

2015
Aminoboration: Addition of B-N σ Bonds across C-C π Bonds.
    Journal of the American Chemical Society, 2015, Aug-19, Volume: 137, Issue:32

    Topics: Amines; Boron Compounds; Chemistry Techniques, Synthetic; Heterocyclic Compounds; Indoles; Pyrroles

2015
Catalytic enantioselective addition of isocyanoacetate to 3-methyl-4-nitro-5-styrylisoxazoles under phase transfer catalysis conditions.
    Organic & biomolecular chemistry, 2015, Nov-21, Volume: 13, Issue:43

    Topics: Acetates; Catalysis; Cyclization; Isoxazoles; Methylation; Nitriles; Nitro Compounds; Pyrroles; Pyrrolidines; Stereoisomerism

2015
Asymmetric [3+2] Annulation Approach to 3-Pyrrolines: Concise Total Syntheses of (-)-Supinidine, (-)-Isoretronecanol, and (+)-Elacomine.
    Angewandte Chemie (International ed. in English), 2015, Nov-09, Volume: 54, Issue:46

    Topics: Cyclization; Indoles; Molecular Structure; Pyrroles; Pyrrolizidine Alkaloids; Spiro Compounds; Stereoisomerism

2015
Biosynthesis of 2-acetyl-1-pyrroline in rice calli cultures: Demonstration of 1-pyrroline as a limiting substrate.
    Food chemistry, 2016, Apr-15, Volume: 197, Issue:Pt A

    Topics: Odorants; Oryza; Plant Extracts; Pyrroles

2016
Catalytic Asymmetric Total Synthesis of (-)-Actinophyllic Acid.
    Journal of the American Chemical Society, 2016, Mar-16, Volume: 138, Issue:10

    Topics: Catalysis; Copper; Imines; Indole Alkaloids; Oxidation-Reduction; Phosphines; Pyrroles; Stereoisomerism

2016
Synthesis of 2-fluoro-2-pyrrolines via tandem reaction of α-trifluoromethyl-α,β-unsaturated carbonyl compounds with N-tosylated 2-aminomalonates.
    Chemical communications (Cambridge, England), 2016, Apr-07, Volume: 52, Issue:27

    Topics: Ketones; Malonates; Pyrroles

2016
Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins.
    The journal of physical chemistry letters, 2017, Mar-16, Volume: 8, Issue:6

    Topics: Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Mesylates; Models, Molecular; Oxides; Proteins; Pyrroles

2017
Identification of Δ
    Plant signaling & behavior, 2017, Nov-02, Volume: 12, Issue:11

    Topics: Gene Expression Regulation, Plant; Lotus; Ornithine-Oxo-Acid Transaminase; Osmotic Pressure; Proline; Pyrroles; Stress, Physiological

2017
Synthesis and biological evaluation of novel heteroring-annulated pyrrolino-tetrahydroberberine analogues as antioxidant agents.
    Bioorganic & medicinal chemistry, 2018, 10-01, Volume: 26, Issue:18

    Topics: Antioxidants; Berberine; Cell Line; Cell Proliferation; Cell Survival; DNA; DNA Breaks; Dose-Response Relationship, Drug; Ferrous Compounds; Free Radicals; Humans; Hydrogen Peroxide; Keratinocytes; Molecular Structure; Pyrroles; Structure-Activity Relationship

2018
Posttranscriptional spin labeling of RNA by tetrazine-based cycloaddition.
    Organic & biomolecular chemistry, 2019, 02-13, Volume: 17, Issue:7

    Topics: Click Chemistry; Cycloaddition Reaction; Electron Spin Resonance Spectroscopy; Molecular Structure; Nitrogen Oxides; Pyrroles; RNA; Spin Labels; Tetrazoles

2019
I
    Autonomic neuroscience : basic & clinical, 2019, Volume: 217

    Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Diet, High-Fat; Disease Models, Animal; Heart Rate; Imidazoline Receptors; Lipids; Male; Metabolic Syndrome; Microcirculation; Pyrroles; Rats; Rats, Wistar; Sympathetic Nervous System

2019
A molecular electron density theory study on the [3+2] cycloaddition reaction of 5,5-dimethyl-1-pyrroline N-oxide with 2-cyclopentenone.
    Journal of molecular graphics & modelling, 2019, Volume: 92

    Topics: Cycloaddition Reaction; Cyclopentanes; Density Functional Theory; Electrons; Models, Molecular; Molecular Structure; Pyrroles; Stereoisomerism

2019
2-Butyl-2-tert-butyl-5,5-diethylpyrrolidine-1-oxyls: Synthesis and Properties.
    Molecules (Basel, Switzerland), 2020, Feb-14, Volume: 25, Issue:4

    Topics: Antioxidants; Biomedical Research; Electron Transport; Nitrogen Oxides; Organometallic Compounds; Oxidation-Reduction; Oxides; Pyrroles

2020
Base Induced Condensation of Malononitrile with Erlenmeyer Azlactones: An Unexpected Synthesis of Multi-Substituted Δ
    Chemistry & biodiversity, 2020, Volume: 17, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lactones; Molecular Structure; Nitriles; Pyrroles; Structure-Activity Relationship

2020
Discovery of dihydropyrrolidones as novel inhibitors against influenza A virus.
    European journal of medicinal chemistry, 2020, Aug-01, Volume: 199

    Topics: A549 Cells; Animals; Antiviral Agents; Cell Survival; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Humans; Influenza A virus; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Structure-Activity Relationship

2020
Syntheses and Reactions of Pyrroline, Piperidine Nitroxide Phosphonates.
    Molecules (Basel, Switzerland), 2020, May-22, Volume: 25, Issue:10

    Topics: Alkenes; Carbon; Molecular Structure; Nitrogen Oxides; Organophosphonates; Piperidines; Pyrroles; Stereoisomerism

2020
Exogenous proline induces regulation in 2-acetyl-1-pyrroline (2-AP) biosynthesis and quality characters in fragrant rice (Oryza sativa L.).
    Scientific reports, 2020, 08-18, Volume: 10, Issue:1

    Topics: China; Edible Grain; Gene Expression Regulation, Plant; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles

2020
Novel carboxylated pyrroline-2-one derivatives bearing a phenylhydrazine moiety: Design, synthesis, antifungal evaluation and 3D-QSAR analysis.
    Bioorganic & medicinal chemistry letters, 2020, 11-01, Volume: 30, Issue:21

    Topics: Antifungal Agents; Botrytis; Colletotrichum; Dose-Response Relationship, Drug; Drug Design; Fusarium; Microbial Sensitivity Tests; Molecular Structure; Phenylhydrazines; Pyrroles; Quantitative Structure-Activity Relationship; Rhizoctonia

2020
Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities.
    ChemMedChem, 2021, 02-04, Volume: 16, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Density Functional Theory; Fluoresceins; Guinea Pigs; Humans; Molecular Structure; Pyrroles; Reperfusion Injury; Tumor Cells, Cultured; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2021
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 3: Structure-activity relationships of pyrropyrazolone derivatives.
    Bioorganic & medicinal chemistry letters, 2020, 12-15, Volume: 30, Issue:24

    Topics: Drug Discovery; Humans; Molecular Docking Simulation; Purinergic P2X Receptor Antagonists; Pyrazolones; Pyrroles; Receptors, Purinergic P2X3; Structure-Activity Relationship

2020
Cationic Pyrrolidine/Pyrroline-Substituted Porphyrins as Efficient Photosensitizers against
    Molecules (Basel, Switzerland), 2021, Jan-17, Volume: 26, Issue:2

    Topics: Anti-Bacterial Agents; Escherichia coli; Photosensitizing Agents; Porphyrins; Pyrroles; Singlet Oxygen

2021
Antioxidant, Cytotoxic Activity and Pharmacokinetic Studies by Swiss Adme, Molinspiration, Osiris and DFT of PhTAD-substituted Dihydropyrrole Derivatives.
    Current computer-aided drug design, 2022, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Humans; MCF-7 Cells; Molecular Structure; Pyrroles; Structure-Activity Relationship; Switzerland

2022
Novel monocyclic amide-linked phenol derivatives without mitochondrial toxicity have potent uric acid-lowering activity.
    Bioorganic & medicinal chemistry letters, 2021, 05-15, Volume: 40

    Topics: Amides; Animals; Benzbromarone; Drug Evaluation, Preclinical; Glucose Transport Proteins, Facilitative; Humans; Mitochondria; Phenol; Pyrroles; Sapajus apella; Signal Transduction; Structure-Activity Relationship; Uric Acid; Uricosuric Agents

2021
Rhodium-Catalyzed Denitrogenative Transannulation of
    Organic letters, 2021, 08-20, Volume: 23, Issue:16

    Topics: Catalysis; Glycosides; Molecular Structure; Pyrroles; Rhodium; Triazoles

2021
Cytostatic Effect of a Novel Mitochondria-Targeted Pyrroline Nitroxide in Human Breast Cancer Lines.
    International journal of molecular sciences, 2021, Aug-20, Volume: 22, Issue:16

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytostatic Agents; Female; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Nitrogen Oxides; Pyrroles; Reactive Oxygen Species; Triple Negative Breast Neoplasms

2021
Expanding the Protecting Group Scope for the Carbonyl Olefin Metathesis Approach to 2,5-Dihydropyrroles.
    The Journal of organic chemistry, 2022, 01-07, Volume: 87, Issue:1

    Topics: Alkenes; Biological Products; Catalysis; Pyrroles

2022
Synthesis of 1-pyrroline derivatives
    Organic & biomolecular chemistry, 2022, 04-06, Volume: 20, Issue:14

    Topics: Alkynes; Catalysis; Cyclization; Molecular Structure; Pyrroles

2022
Catalytic asymmetric [3 + 2] cycloaddition of pyrazolone-derived MBH carbonate: highly stereoselective construction of the bispiro-[pyrazolone-dihydropyrrole-oxindole] skeleton.
    Chemical communications (Cambridge, England), 2022, Apr-28, Volume: 58, Issue:35

    Topics: Carbonates; Catalysis; Cycloaddition Reaction; Molecular Structure; Oxindoles; Pyrazolones; Pyrroles; Skeleton; Stereoisomerism

2022
Endoplasmic Reticulum Stress-Induced Apoptotic Effects of Novel 1-Pyrroline (3,4-Dihydro-2H-pyrrole) Derivatives on Breast Cancer Cells.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Endoplasmic Reticulum Stress; Female; Humans; Pyrroles; Reactive Oxygen Species

2022
Synthesis of dihydropyrroles from
    Chemical communications (Cambridge, England), 2022, Nov-01, Volume: 58, Issue:87

    Topics: Catalysis; Cyclization; Cyclopropanes; Pyrroles

2022
New Pyrroline Isolated from Antarctic Krill-Derived Actinomycetes
    Marine drugs, 2023, Feb-15, Volume: 21, Issue:2

    Topics: Actinobacteria; Actinomyces; Animals; Antarctic Regions; Antifungal Agents; Ecosystem; Euphausiacea; Nocardiopsis; Pyrroles

2023