pyrrolidonecarboxylic acid and thyroxine

pyrrolidonecarboxylic acid has been researched along with thyroxine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's13 (54.17)18.2507
2000's3 (12.50)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Metcalf, G; Myers, RD1
Kakucska, I; Lechan, RM; Rand, W1
Hirooka, Y; Kimura, M; Mitsuma, T; Nogimori, T1
Eckland, DJ; Guiloff, RJ; Lightman, SL; Modarres-Sadeghi, H1
Hirooka, Y; Mitsuma, T; Nogimori, T; Yuasa, K1
Baidwan, JS; Harvey, S1
Hershman, JM; Pekary, AE; Simard, M; Smith, VP1
Bansinath, M; Bhargava, HN; Das, S; Prasad, R1
Eckland, DJ; Lightman, SL1
Bissette, G; Brazeau, P; Kizer, JS; Martin, JB; Nemeroff, CB; Prange, AJ; Vale, W1
Arison, BH; Hirschmann, R; Holly, FW; Homnick, C; Nutt, RF; Veber, DF1
Hirooka, Y; Kayama, K; Mitsuma, T; Nogimori, T; Tomari, Y1
de Greef, WJ; Hermus, AR; Kaptein, E; Klootwijk, W; Linkels, E; Sweep, CG; van der Meer, MJ; van Haasteren, GA; van Toor, H; Visser, TJ1
Bolduc, TG; Bruhn, TO; Jackson, IM; Rondeel, JM1
de Greef, WJ; de Jong, FH; Kaptein, E; Klootwijk, W; Linkels, E; Reymond, MJ; van Haasteren, GA; van Toor, H; Visser, TJ1
Ahima, RS; Emerson, CH; Flier, JS; Lechan, RM; Légrádi, G1
Berezina, GP; Iakovenko, IG; Murzina, NB; Obukhova, GG; Rubina, AIu; Timoshin, SS1
Cremades, A; Del Rio-Garcia, J; Peñafiel, R; Rausell, V; Smyth, DG1
Yang, H; Yuan, PQ1
Emerson, CH; Fekete, C; Huang, QH; Lechan, RM; Légrádi, G; Mihály, E; Rand, WM; Tatro, JB1
Clausen, JT; Emerson, CH; Fekete, C; Jackson, IM; Kelly, J; Kuhar, M; Lechan, RM; Luo, LG; Mao, Q; Mihály, E; Moss, LG; Rand, WM1
Charli, JL; Fekete, C; Lechan, RM; Pascual, I; Romero, F; Sánchez, E; Singru, PS; Vargas, MA1
Harney, JW; Larsen, PR; Lechan, RM; Marsili, A; Sanchez, E; Singru, P; Zavacki, AM1
Cabral, A; Charli, JL; Jaimes-Hoy, L; Joseph-Bravo, P; Lazcano, I; Perello, M; Sánchez-Jaramillo, E; Uribe, RM1

Trials

1 trial(s) available for pyrrolidonecarboxylic acid and thyroxine

ArticleYear
The TSH, T4, T3 and prolactin responses to consecutive infusions of a potent and stabilized thyrotrophin releasing hormone analogue, RX77368, in man.
    European journal of clinical investigation, 1988, Volume: 18, Issue:4

    Topics: Adult; Central Nervous System; Humans; Male; Prolactin; Pyrrolidonecarboxylic Acid; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1988

Other Studies

23 other study(ies) available for pyrrolidonecarboxylic acid and thyroxine

ArticleYear
A comparison between the hypothermia induced by intra-ventricular injections of thyrotropin releasing hormone, noradrenaline or calcium ions in unanaesthetized cats.
    British journal of pharmacology, 1976, Volume: 58, Issue:4

    Topics: Animals; Body Temperature; Calcium; Cats; Female; Histidine; Injections, Intraventricular; Male; Methyltyrosines; Norepinephrine; Phentolamine; Proline; Pyrrolidonecarboxylic Acid; Respiration; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Time Factors

1976
Thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is dependent upon feedback regulation by both triiodothyronine and thyroxine.
    Endocrinology, 1992, Volume: 130, Issue:5

    Topics: Animals; Feedback; Gene Expression Regulation; Hypothyroidism; Infusions, Parenteral; Male; Methimazole; Paraventricular Hypothalamic Nucleus; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Regression Analysis; RNA, Messenger; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1992
Effects of hypophysectomy on pro-thyrotropin-releasing hormone concentrations in rats.
    Experimental and clinical endocrinology, 1991, Volume: 97, Issue:1

    Topics: Animals; Brain Stem; Cerebellum; Cerebral Ventricles; Eye; Gastric Mucosa; Hypophysectomy; Hypothalamus; Male; Pituitary Gland; Protein Precursors; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1991
The effects of repeated administration of a long acting TRH analogue (RX77368), on TSH, T4, T3 and prolactin in patients with motor neuron disease.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:9

    Topics: Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Motor Neurons; Neuromuscular Diseases; Prolactin; Pyrrolidonecarboxylic Acid; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1990
Effects of thyroid hormone, TRH and TSH on pro-TRH concentrations in various organs of rats.
    Endocrinologia experimentalis, 1990, Volume: 24, Issue:4

    Topics: Animals; Brain; Brain Stem; Cerebellum; Eye; Gastric Mucosa; Hypothalamus; Male; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Stomach; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1990
Thyroidal inhibition of growth hormone secretion in fowl: tri-iodothyronine-induced down-regulation of thyrotrophin-releasing hormone-binding sites on pituitary membranes.
    Journal of molecular endocrinology, 1990, Volume: 4, Issue:2

    Topics: Animals; Binding Sites; Cell Membrane; Chickens; Down-Regulation; Growth Hormone; Hypothyroidism; Methimazole; Pituitary Gland; Pyrrolidonecarboxylic Acid; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1990
Thyroid hormones modulate thyrotropin-releasing hormone biosynthesis in tissues outside the hypothalamic-pituitary axis of male rats.
    Endocrinology, 1989, Volume: 125, Issue:1

    Topics: Adrenal Glands; Animals; Chromatography; Male; Pancreas; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Tissue Distribution; Triiodothyronine

1989
The binding of 3H-(3-MeHis2) thyrotropin releasing hormone to brain and pituitary membranes of morphine tolerant-dependent and abstinent rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1

    Topics: Animals; Brain; Cell Membrane; Drug Tolerance; Male; Morphine; Morphine Dependence; Naloxone; Pituitary Gland; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1989
Effect of chronic treatment with thyrotropin-releasing hormone (TRH) or an analog of TRH (linear beta-alanine TRH) on the hypothalamic-pituitary-thyroid axis.
    Neuroendocrinology, 1980, Volume: 30, Issue:4

    Topics: Animals; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Mice; Pyrrolidonecarboxylic Acid; Rats; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1980
Synthesis of thyrotropin-releasing hormone analogues with selective central nervous system effects.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:6

    Topics: Central Nervous System; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazolidines; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1981
Effects of hypophysectomy on TRH and its related peptides concentrations in various rat organs.
    Endocrine regulations, 1994, Volume: 28, Issue:3

    Topics: Animals; Brain; Brain Stem; Cerebellum; Gastric Mucosa; Hypophysectomy; Hypothalamus; Male; Pituitary Gland; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Retina; Stomach; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1994
Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis.
    Endocrinology, 1994, Volume: 135, Issue:4

    Topics: Animals; Body Temperature; Body Weight; Corticosterone; Drinking; Eating; Gene Expression; Hypothalamo-Hypophyseal System; Hypothalamus; Interleukin-1; Interleukin-6; Male; Median Eminence; Pituitary Gland; Protein Precursors; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Wistar; RNA, Messenger; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1994
Thyrotropin-releasing hormone gene expression in the anterior pituitary. III. Stimulation by thyroid hormone: potentiation by glucocorticoids.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: Animals; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression; In Situ Hybridization; Kinetics; Male; Pituitary Gland, Anterior; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; RNA, Messenger; Thyrotropin-Releasing Hormone; Thyroxine; Time Factors; Triiodothyronine

1994
Effects of long-term food reduction on the hypothalamus-pituitary-thyroid axis in male and female rats.
    The Journal of endocrinology, 1996, Volume: 150, Issue:2

    Topics: Animals; Body Weight; Corticosterone; Female; Food Deprivation; Hypothalamo-Hypophyseal System; Male; Pituitary Gland; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; RNA, Messenger; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1996
Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus.
    Endocrinology, 1997, Volume: 138, Issue:6

    Topics: Animals; Fasting; Hypothalamo-Hypophyseal System; Leptin; Male; Mice; Neurons; Obesity; Paraventricular Hypothalamic Nucleus; Prealbumin; Protein Precursors; Proteins; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Transcription, Genetic; Triiodothyronine

1997
[Hydra peptide morphogen attenuates poststress disorders in the white rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1997, Volume: 124, Issue:10

    Topics: Animals; Cell Division; Corticosterone; Epithelium, Corneal; Lipid Peroxidation; Male; Neuropeptides; Organ Size; Pylorus; Pyrrolidonecarboxylic Acid; Rats; Stress, Physiological; Thymus Gland; Thyrotropin; Thyroxine

1997
The thyrotropin-releasing hormone-like peptides pGlu-Phe-Pro amide and pGlu-Glu-Pro amide increase plasma triiodothyronine levels in the mouse; the activity is sensitive to testosterone.
    European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1

    Topics: Animals; Antineoplastic Agents, Hormonal; Castration; Female; Male; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Testosterone; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1998
Hyperthyroidism decreases thyrotropin-releasing hormone gene expression in the caudal raphe nuclei and the parapyramidal regions in rats.
    Neuroscience letters, 1999, Dec-10, Volume: 276, Issue:3

    Topics: Animals; Gene Expression; Hyperthyroidism; Male; Medulla Oblongata; Protein Precursors; Pyramidal Tracts; Pyrrolidonecarboxylic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P; Thyroidectomy; Thyrotropin-Releasing Hormone; Thyroxine

1999
alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone ge
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Feb-15, Volume: 20, Issue:4

    Topics: alpha-MSH; Animals; Body Weight; Fasting; Gene Expression Regulation; Immunohistochemistry; In Situ Hybridization; Male; Microscopy, Immunoelectron; Nerve Endings; Neurons; Paraventricular Hypothalamic Nucleus; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine

2000
Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid a
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Dec-15, Volume: 20, Issue:24

    Topics: alpha-MSH; Animals; Behavior, Animal; Body Weight; Cell Count; Cells, Cultured; Colchicine; Fasting; Fluorescent Dyes; Hypothalamo-Hypophyseal System; Hypothalamus; Injections, Intraventricular; Male; Nerve Tissue Proteins; Neurons; Paraventricular Hypothalamic Nucleus; Presynaptic Terminals; Protein Precursors; Pyrrolidonecarboxylic Acid; Radiography; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stilbamidines; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine

2000
Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence.
    Endocrinology, 2009, Volume: 150, Issue:5

    Topics: Aminopeptidases; Animals; Axons; Cell Communication; Gene Expression Regulation, Enzymologic; Hypothalamo-Hypophyseal System; Male; Median Eminence; Models, Biological; Neuroglia; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Tissue Distribution

2009
Thyroxine-induced expression of pyroglutamyl peptidase II and inhibition of TSH release precedes suppression of TRH mRNA and requires type 2 deiodinase.
    The Journal of endocrinology, 2011, Volume: 211, Issue:1

    Topics: Aminopeptidases; Animals; Antithyroid Agents; Disease Models, Animal; Hypothyroidism; Injections, Intraperitoneal; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Mice; Mice, Inbred C57BL; Mice, Knockout; Paraventricular Hypothalamic Nucleus; Pyrrolidonecarboxylic Acid; RNA, Messenger; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

2011
Fasting Enhances Pyroglutamyl Peptidase II Activity in Tanycytes of the Mediobasal Hypothalamus of Male Adult Rats.
    Endocrinology, 2015, Volume: 156, Issue:7

    Topics: Adrenalectomy; Aminopeptidases; Animals; Antithyroid Agents; Corticosterone; Ependymoglial Cells; Fasting; Hypothalamo-Hypophyseal System; Hypothalamus; Hypothyroidism; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Median Eminence; Methimazole; Paraventricular Hypothalamic Nucleus; Protein Precursors; Pyrrolidonecarboxylic Acid; Rats; RNA, Messenger; Thyrotropin-Releasing Hormone; Thyroxine

2015