pyrrolidonecarboxylic acid has been researched along with glutamine in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (35.94) | 18.7374 |
| 1990's | 11 (17.19) | 18.2507 |
| 2000's | 13 (20.31) | 29.6817 |
| 2010's | 9 (14.06) | 24.3611 |
| 2020's | 8 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Orlowski, M | 1 |
| Orlowski, M; Wilk, S | 1 |
| Meister, A | 2 |
| Burstein, Y; Schechter, I | 1 |
| Baechtel, FS; Gregg, DE; Prager, MD | 1 |
| Ando, T; Kilroy, A; Nyhan, WL; Sweetman, L; Wadlington, WB | 1 |
| Lusty, CJ | 1 |
| Hagan, RM; Jordan, CC; Karagiannis, K; Manolopoulou, A; Poulos, C; Stavropoulos, G | 1 |
| Fujiwara, F; Funahashi, S; Hayashi, A; Nakanishi, T; Saiki, K; Shimizu, A | 1 |
| Chen, GJ; Russell, JB | 2 |
| Shih, FF | 1 |
| Bellon, G; Borel, JP; Monboisse, JC; Randoux, A | 1 |
| Anderson, LW; Strong, JM; Zaharevitz, DW | 1 |
| Koelle, GB; Sanville, UJ; Thampi, NS; Wall, SJ | 1 |
| Fischer, WH; Spiess, J | 1 |
| Meister, A; Weisbrod, RE | 1 |
| Brewer, HB; John, KM; Lux, SE | 1 |
| Fraser, KJ; Haber, E; Pulsen, K | 1 |
| Munro, AJ; Stott, DI | 1 |
| Bradenberger, H; Hediger, H; Schmid, K; Stevens, L | 1 |
| Finkelstein, BS; Levin, M; Tabachnick, J; Wolfersberger, MG | 1 |
| Barrett, JG; Scott, IR | 1 |
| Prusiner, SB | 1 |
| Dimarchi, RD; Kent, SB; Merrifield, RB; Tam, JP | 1 |
| Anagnostides, S; Chorev, M; Karagiannis, K; Ministrouski, I; Selinger, Z; Stavropoulos, G | 1 |
| Bílek, R; Bradbury, AF; Smyth, DG | 1 |
| Kamo, M; Miyatake, N; Satake, K; Tsugita, A; Uchiyama, Y | 1 |
| Eichner, K; Schräder, I | 1 |
| Floyd, PD; Garden, RW; Gleeson, JM; Li, L; Moroz, TP; Rubakhin, SS; Sweedler, JV | 1 |
| Carter, P; Schuldt, S; Welbourne, T | 1 |
| Hammarqvist, F; Wernerman, J | 1 |
| Alba, F; Martínez, JM; Prieto, I; Ramírez, M; Ramírez, MJ | 1 |
| Blaszczyk, J; Bujacz, GD; Coillie, EV; Damme, JV; Ji, X; Opdenakker, G; Proost, P; Wang, JM | 1 |
| Bearne, SL; Hekmat, O; Macdonnell, JE | 1 |
| Fellermann, K; Grohs, M; Lindemann, G; Stange, EF | 1 |
| Chen, G; Chen, W; Ling, Z; Luo, G; Qu, J; Wang, Y; Xiao, S | 1 |
| Carrera, MP; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ; Tsuboyama, GK | 1 |
| Butz, P; Fernández García, A; Pfaff, E; Stärke, J; Tauscher, B; Trierweiler, B; Zöller, H | 1 |
| Demuth, HU; Hoffmann, T; Ludwig, HH; Manhart, S; Schilling, S; Wasternack, C | 1 |
| de Haan, EC; Grosfeld-Stulemeyer, MC; Liskamp, RM; Moret, EE; Rijkers, DT; Wagenaar-Hilbers, JP; Wauben, MH | 1 |
| Feng, L; Sheppard, K; Söll, D; Tumbula-Hansen, D | 1 |
| Baab, PJ; Huang, Y; Mena, FV; Zielke, CL; Zielke, HR | 1 |
| Hawkins, RA; O'Kane, RL; Simpson, IA; Viña, JR | 1 |
| Demuth, HU; Koch, B; Lindner, C; Rahfeld, JU; Reuter, G; Rudolph, T; Schilling, S; von Bohlen, A; Wermann, M | 1 |
| Ackermann, BL; Ammerman, GM; Eckstein, JA; Reveles, JM | 1 |
| Görlach, M; Gührs, KH; Mischo, A; Ohlenschläger, O | 1 |
| Liu, H; Paporello, B; Peng, Y; Richardson, D; Wang, F; Xu, W | 1 |
| Hawke, DH; Lorenzi, PL; Purwaha, P; Silva, LP; Weinstein, JN | 1 |
| Gowda, YN; Nagana Gowda, GA; Raftery, D | 1 |
| Demuth, HU; Ludwig, HH; Schilling, S; Seifert, F; Tittmann, K; Weichler, T | 1 |
| Inoue, K; Min, JZ; Miyazaki, Y; Todoroki, K; Toyo'oka, T; Unno, K | 1 |
| Kaufmann, M; Kroh, LW; Wegener, S | 1 |
| Abramovich, R; Deigin, V; Dubinnyi, M; Ivanov, V; Ksenofontova, O; Kublitsky, V; Shmygarev, V; Yatskin, O | 1 |
| Bolgar, M; Chennamsetty, N; Lin, S; Liu, Z; Qiu, D; Valente, J | 1 |
| Deatherage, T; Denton, TT; Kruger, L; Shen, D | 1 |
| Atzori, L; Conte, S; Finco, G; Leoni, VP; Muntoni, S; Pibiri, M; Piras, C; Rao, G | 1 |
| Liang, P; Liu, J; Ou, M; Wei, Y; Zhang, D; Zhou, C; Zuo, Y | 1 |
| Kang, HG; Kwon, S; Lee, J; Lee, S; Lee, YR | 1 |
| Gao, R; Su, W; Wang, R; Xu, Y; Zeng, Q; Zhang, M; Zhou, S; Zhu, G | 1 |
| Knight, TJ; Martinez, RA; Unkefer, PJ | 1 |
| Asadollahi, K; de Zhang, LA; Gooley, PR; Huang, K; Scott, DJ; Yan, F | 1 |
| Barg, E; Bodetko, A; Hetman, M; Mielko, K; Młynarz, P; Placzkowska, S | 1 |
6 review(s) available for pyrrolidonecarboxylic acid and glutamine
| Article | Year |
|---|---|
Possible role of glutathione in transport processes.
Topics: Acidosis; Amino Acids; Animals; Biological Transport, Active; Brain; Capillaries; Cell Membrane; Choroid Plexus; Ciliary Body; Epithelium; gamma-Glutamyltransferase; Glutamine; Glutathione; Humans; Intestinal Mucosa; Kidney; Lens, Crystalline; Liver Diseases; Organ Specificity; Peptide Synthases; Pyrrolidonecarboxylic Acid | 1976 |
Function of glutathione in kidney via the gamma-glutamyl cycle.
Topics: Acyltransferases; Adult; Amino Acids; Animals; Cysteine; Dipeptidases; gamma-Glutamylcyclotransferase; gamma-Glutamyltransferase; Glutamates; Glutaminase; Glutamine; Glutathione; Glycine; Humans; Kidney; Male; Metabolism, Inborn Errors; Peptide Synthases; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Transaminases | 1975 |
An enzymatic basis for a blood-brain barrier? The gamma-glutamyl cycle-background and considerations relating to amino acid transport in the brain.
Topics: Acyltransferases; Adult; Amidohydrolases; Amino Acids; Animals; Blood-Brain Barrier; Brain; Choroid Plexus; Cysteine; gamma-Glutamyltransferase; Glutamates; Glutamine; Glutathione; Humans; Male; Methionine Sulfoximine; Mice; Peptide Synthases; Proline; Pyrrolidonecarboxylic Acid; Rabbits | 1974 |
Disorders of glutamate metabolism and neurological dysfunction.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Histidine; Humans; Ketoglutaric Acids; Nervous System Diseases; Proline; Pyrrolidonecarboxylic Acid | 1981 |
Modulation of endogenous glutathione availability.
Topics: Acetylcysteine; Animals; Cysteine; Glutamine; Glutathione; Humans; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
Structure of the blood-brain barrier and its role in the transport of amino acids.
Topics: Amino Acids; Ammonia; Animals; Biological Transport; Blood-Brain Barrier; gamma-Glutamyltransferase; Glutamic Acid; Glutamine; Humans; Pyrrolidonecarboxylic Acid; Sodium | 2006 |
58 other study(ies) available for pyrrolidonecarboxylic acid and glutamine
| Article | Year |
|---|---|
Metabolism of gamma-glutamyl amino acids and peptides in mouse liver and kidney in vivo.
Topics: Aminobutyrates; Animals; Aspartic Acid; gamma-Glutamyltransferase; Glutamates; Glutamine; Glutathione; Kidney; Liver; Male; Mice; Peptides; Pyrrolidonecarboxylic Acid | 1976 |
Glutamine as a precursor to N-terminal pyrrolid-2-one-5-carboxylic acid in mouse immunoglobulin lambda-type light chains. Amino acid-sequence variability at the N-terminal extra piece of lambda-type light-chain precursors.
Topics: Amino Acid Sequence; Animals; Glutamine; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Mice; Myeloma Proteins; Peptide Chain Termination, Translational; Pyrrolidinones; Pyrrolidonecarboxylic Acid; RNA, Messenger | 1977 |
The influence of glutamine, its decomposition products, and glutaminase on the transformation of human and mouse lymphocytes.
Topics: Adult; Ammonia; Animals; B-Lymphocytes; Female; Glutaminase; Glutamine; Humans; Lectins; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pyrrolidonecarboxylic Acid; T-Lymphocytes; Thymidine | 1976 |
Hyperglycinemia and propionyl coA carboxylase deficiency and episodic severe illness without consistent ketosis.
Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Amino Acids; Citrates; Coenzyme A; Creatinine; Crotonates; Glutamates; Glutamine; Glycine; Humans; Infant; Ketone Bodies; Ketosis; Ligases; Male; Propionates; Pyrrolidonecarboxylic Acid | 1975 |
Detection of an enzyme bound gamma-glutamyl acyl ester of carbamyl phosphate synthetase of Escherichia coli.
Topics: Acids; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cysteine; Escherichia coli; Esters; Glutamates; Glutamine; Hydrolysis; Hydroxamic Acids; Kinetics; Mutation; Pyrrolidonecarboxylic Acid; Serine | 1992 |
Synthesis of a potent agonist of substance P by modifying the methionyl and glutaminyl residues of the C-terminal hexapeptide of substance P. Structure-activity relationships.
Topics: Amino Acid Sequence; Animals; Biological Assay; Colon; Glutamine; Guinea Pigs; Ileum; Methionine; Molecular Sequence Data; Peptide Fragments; Portal Vein; Pyrrolidonecarboxylic Acid; Rats; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Structure-Activity Relationship; Substance P | 1991 |
Quantitative analysis of urinary pyroglutamic acid in patients with hyperammonemia.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Metabolism, Inborn Errors; Ammonia; Carbamoyl-Phosphate Synthase (Ammonia); Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Infant; Infant, Newborn; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Pyrrolidonecarboxylic Acid; Urea | 1991 |
Effects of monensin and pH on the production and utilization of pyro-glutamate, a novel product of ruminal glutamine deamination.
Topics: Animals; Bacteria; Cattle; Deamination; Female; Fermentation; Glutamine; Hydrogen-Ion Concentration; Monensin; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rumen | 1989 |
Transport of glutamine by Streptococcus bovis and conversion of glutamine to pyroglutamic acid and ammonia.
Topics: Ammonia; Biological Transport, Active; Glutamates; Glutamine; Ketoglutaric Acids; NADP; Pyrrolidonecarboxylic Acid; Streptococcus | 1989 |
Analysis of glutamine, glutamic acid and pyroglutamic acid in protein hydrolysates by high-performance liquid chromatography.
Topics: Caseins; Chromatography, High Pressure Liquid; Drug Stability; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Protein Hydrolysates; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1985 |
Effects of preformed proline and proline amino acid precursors (including glutamine) on collagen synthesis in human fibroblast cultures.
Topics: Amino Acids; Aspartic Acid; Cells, Cultured; Fibroblasts; Glutamates; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Ornithine; Procollagen; Proline; Pyrrolidonecarboxylic Acid; RNA, Transfer, Amino Acyl | 1987 |
Glutamine and glutamate: automated quantification and isotopic enrichments by gas chromatography/mass spectrometry.
Topics: Animals; Gas Chromatography-Mass Spectrometry; Glutamates; Glutamic Acid; Glutamine; Nitrogen Isotopes; Pyrrolidonecarboxylic Acid; Rats | 1987 |
L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat.
Topics: Acetylcholinesterase; Animals; Aspartic Acid; Butyrylcholinesterase; Cats; Cholinesterases; Denervation; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Glutamates; Glutamine; Glycine; Pyrrolidonecarboxylic Acid | 1986 |
Identification of a mammalian glutaminyl cyclase converting glutaminyl into pyroglutamyl peptides.
Topics: Acyltransferases; Amino Acid Sequence; Amino Acids; Aminoacyltransferases; Animals; Cattle; Chromatography, Gel; Chromatography, High Pressure Liquid; Glutamine; Kinetics; Oligopeptides; Pituitary Gland; Protein Processing, Post-Translational; Pyrrolidonecarboxylic Acid; Trypsin | 1987 |
Studies on glutamine synthetase from Escherichia coli. Formation of pyrrolidone carboxylate and inhibition by methionine sulfoximine.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Brain; Escherichia coli; Glutamate-Ammonia Ligase; Glutamine; Kinetics; Magnesium; Manganese; Methionine Sulfoximine; Protein Binding; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Sheep; Species Specificity; Stereoisomerism | 1973 |
Isolation and characterization of apoLp-Gln-II (apoA-II), a plasma high density apolipoprotein containing two identical polypeptide chains.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Apoproteins; Black People; Carboxypeptidases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Female; Glutamine; Humans; Immunoelectrophoresis; Lipoproteins; Lipoproteins, HDL; Molecular Weight; Oxidation-Reduction; Peptides; Pseudomonas fluorescens; Pyrrolidonecarboxylic Acid; Threonine | 1972 |
Specific cleavage between variable and constant domains of rabbit antibody light chains by dilute acid hydrolysis.
Topics: 1-Propanol; Acetates; Alanine; Alkylation; Amino Acid Sequence; Amino Acids; Animals; Antibodies, Bacterial; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Gel; Glutamine; Guanidines; Hydrogen-Ion Concentration; Hydrolysis; Immunoglobulin Fragments; Oxidation-Reduction; Polysaccharides, Bacterial; Proline; Pyridines; Pyrrolidonecarboxylic Acid; Rabbits; Streptococcus pneumoniae; Thiocyanates; Time Factors | 1972 |
The formation of pyrrolid-2-one-5-carboxylic acid at the N-terminus of immunoglobulin G heavy chain.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carbon Isotopes; Glutamine; Immunoglobulin Fc Fragments; Immunoglobulin Fragments; Immunoglobulin G; Liver; Mice; Plasmacytoma; Pyrrolidinones; Pyrrolidonecarboxylic Acid; RNA, Transfer; Tritium; Valine | 1972 |
Determination of asparagine, glutamine and pyrrolidonecarboxylic acid in total enzymic hydrolysates of peptides and glycopeptides by gas-liquid chromatography.
Topics: Amino Acids; Asparagine; Chromatography, Gas; Enzymes; Esters; Fluoroacetates; Glutamine; Glycopeptides; Homoserine; Hydrolysis; Hydroxylysine; Lysine; Methods; Peptides; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1973 |
L-pyrrolidone carboxylic acid content in mammalian epidermis and other tissues.
Topics: Amino Acids; Animals; Brain Chemistry; Carboxylic Acids; Dogs; Erythrocytes; Glutamates; Glutamine; Guinea Pigs; Humans; Intestines; Kidney; Liver; Male; Mice; Optical Rotatory Dispersion; Pancreas; Pyrrolidines; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Rats; Skin; Spleen | 1973 |
Pyrrolidone carboxylic acid synthesis in guinea pig epidermis.
Topics: Animals; Epidermis; gamma-Glutamylcyclotransferase; Glutamine; Guinea Pigs; Male; Pyroglutamyl-Peptidase I; Pyrrolidinones; Pyrrolidonecarboxylic Acid | 1983 |
Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling.
Topics: Chemical Phenomena; Chemistry; Dicyclohexylcarbodiimide; Dimethylformamide; Glutamine; Oligopeptides; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Trifluoroacetic Acid | 1982 |
Synthesis of potent agonists of substance P by replacement of Met11 with Glu(OBzl) and N-terminal glutamine with Glp of the C-terminal hexapeptide and heptapeptide of substance P.
Topics: Amino Acid Sequence; Animals; Biological Assay; Glutamine; Guinea Pigs; Methionine; Molecular Sequence Data; Muscle, Smooth; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P | 1995 |
Synthesis and high-performance liquid chromatographic purification of tritiated thyrotrophin-releasing hormone-like peptides.
Topics: Amino Acid Sequence; Anhydrides; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glutamine; Humans; Isotope Labeling; Male; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Prostate; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Thyrotropin-Releasing Hormone | 1994 |
Removal of N-terminal formyl groups and deblocking of pyrrolidone carboxylic acid of proteins with anhydrous hydrazine vapor.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Dipeptides; Formates; Glutamine; Hydrazines; Indicators and Reagents; Molecular Sequence Data; Neurotensin; Oligopeptides; Peptides; Phenylthiohydantoin; Pyrrolidonecarboxylic Acid; Spectrometry, Mass, Fast Atom Bombardment | 1993 |
[Changes in chemical composition of tomatoes during processing].
Topics: Amino Acids; Carbohydrates; Chromatography, Gas; Cold Temperature; Food Handling; Glutamine; Hot Temperature; Maillard Reaction; Pectins; Pyrrolidonecarboxylic Acid; Solanum lycopersicum | 1996 |
Formation of N-pyroglutamyl peptides from N-Glu and N-Gln precursors in Aplysia neurons.
Topics: Amino Acid Sequence; Animals; Aplysia; Ganglia, Invertebrate; Glutamic Acid; Glutamine; Molecular Sequence Data; Neurons; Peptide Fragments; Protein Precursors; Pyrrolidonecarboxylic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Water-Electrolyte Balance | 1999 |
Glutamate transport asymmetry and metabolism in the functioning kidney.
Topics: Animals; Aspartic Acid; Biological Transport; Glutamic Acid; Glutamine; In Vitro Techniques; Kidney; Male; Perfusion; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1999 |
Influence of dietary supplementation with olive oil on pyroglutamyl-beta-naphthylamide hydrolysing activity in serum and different tissues of mice.
Topics: Animals; Dietary Fats, Unsaturated; Glutamine; Hydrolysis; Male; Membranes; Mice; Mice, Inbred BALB C; Naphthalenes; Olive Oil; Plant Oils; Pyroglutamyl-Peptidase I; Pyrrolidonecarboxylic Acid; Solubility; Substrate Specificity; Tissue Distribution | 1998 |
Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors.
Topics: Amino Acid Sequence; Chemokine CCL8; Chemotaxis; Crystallization; Crystallography, X-Ray; Glutamine; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Monocyte Chemoattractant Proteins; Peptide Fragments; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Pyrrolidonecarboxylic Acid; Receptors, Chemokine | 2000 |
Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.
Topics: Allosteric Regulation; Aminobutyrates; Carbon-Nitrogen Ligases; Cysteine; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Glutamates; Glutamine; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Pyrroles; Pyrrolidonecarboxylic Acid; Quaternary Ammonium Compounds; Recombinant Proteins | 2001 |
Limited heat-shock protein 72 induction in Caco-2 cells by L-glutamine.
Topics: Alanine; Blotting, Western; Caco-2 Cells; Densitometry; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glutamine; Glycine; Heat-Shock Proteins; Hot Temperature; Humans; In Vitro Techniques; Luminescent Measurements; Pyrrolidonecarboxylic Acid | 2001 |
Rapid determination of underivatized pyroglutamic acid, glutamic acid, glutamine and other relevant amino acids in fermentation media by LC-MS-MS.
Topics: Amino Acids; Bioreactors; Chromatography, Liquid; Corynebacterium; Culture Media; Fermentation; Glutamic Acid; Glutamine; Mass Spectrometry; Pyrrolidonecarboxylic Acid | 2002 |
Effects of dietary cholesterol on pyroglutamyl aminopeptidase activity in mouse frontal cortex, pituitary, and adrenal glands.
Topics: Adrenal Glands; Aminopeptidases; Animals; Cholesterol, Dietary; Female; Fluorometry; Glutamine; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred BALB C; Naphthalenes; Pituitary Gland; Prefrontal Cortex; Pyrrolidonecarboxylic Acid; Sex Characteristics; Thyrotropin-Releasing Hormone | 2002 |
Pressure/temperature combined treatments of precursors yield hormone-like peptides with pyroglutamate at the N terminus.
Topics: Cyclization; Glutamine; Hot Temperature; Hydrogen-Ion Concentration; Peptide Hormones; Pressure; Protein Precursors; Pyrrolidonecarboxylic Acid; Solutions; Thyrotropin-Releasing Hormone | 2003 |
Substrate specificity of glutaminyl cyclases from plants and animals.
Topics: Amino Acids; Aminoacyltransferases; Animals; Carica; Catalysis; Cattle; Cyclization; Dipeptides; Enzyme Stability; Gastrins; Glutamate Dehydrogenase; Glutamine; Gonadotropin-Releasing Hormone; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; NAD; Neurotensin; Oligopeptides; Osmolar Concentration; Pyrrolidonecarboxylic Acid; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thyrotropin-Releasing Hormone | 2003 |
Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies.
Topics: Acetylation; Acetyltransferases; Animals; Glutamine; Guinea Pigs; Hot Temperature; Major Histocompatibility Complex; Myelin Basic Protein; Peptide Fragments; Pyrrolidonecarboxylic Acid; T-Lymphocytes; Time Factors | 2004 |
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Archaea; Asparaginase; Aspartic Acid; Binding Sites; Chromatography, Thin Layer; Cloning, Molecular; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hydrolysis; Lysine; Methanobacteriaceae; Models, Chemical; Mutation; Phosphorylation; Protein Biosynthesis; Protein Kinases; Pyrrolidonecarboxylic Acid; RNA, Transfer; RNA, Transfer, Gln; Threonine | 2005 |
Formation of extracellular glutamate from glutamine: exclusion of pyroglutamate as an intermediate.
Topics: Animals; Carbon Isotopes; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.
Topics: Amino Acid Sequence; Aminoacyltransferases; Animals; Catalysis; Cell Line; Chromatography, Liquid; Circular Dichroism; Cloning, Molecular; DNA Primers; Drosophila; Enzyme Activation; Escherichia coli; Glutamine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Pichia; Pyrrolidonecarboxylic Acid; Recombinant Fusion Proteins; Sequence Alignment; Subcellular Fractions; Substrate Specificity | 2007 |
Analysis of glutamine, glutamate, pyroglutamate, and GABA in cerebrospinal fluid using ion pairing HPLC with positive electrospray LC/MS/MS.
Topics: Animals; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Pyrrolidonecarboxylic Acid; Rats; Spectrometry, Mass, Electrospray Ionization | 2008 |
Recombinant production of isotope-labeled peptides and spontaneous cyclization of amino-terminal glutamine into pyroglutamic acid.
Topics: Amyloid beta-Peptides; Cyclization; Glutamine; Isotope Labeling; Magnetic Resonance Spectroscopy; Pyrrolidonecarboxylic Acid; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Method to convert N-terminal glutamine to pyroglutamate for characterization of recombinant monoclonal antibodies.
Topics: Antibodies, Monoclonal; Biocatalysis; Chromatography, High Pressure Liquid; Cyclization; Glutamine; Mass Spectrometry; Pyrrolidonecarboxylic Acid; Recombinant Proteins | 2013 |
An artifact in LC-MS/MS measurement of glutamine and glutamic acid: in-source cyclization to pyroglutamic acid.
Topics: Artifacts; Chromatography, Liquid; Cyclization; Flow Injection Analysis; Glutamic Acid; Glutamine; Pyrrolidonecarboxylic Acid; Tandem Mass Spectrometry | 2014 |
Massive glutamine cyclization to pyroglutamic acid in human serum discovered using NMR spectroscopy.
Topics: Cyclization; Glutamine; Humans; Magnetic Resonance Spectroscopy; Pyrrolidonecarboxylic Acid | 2015 |
Phosphate ions and glutaminyl cyclases catalyze the cyclization of glutaminyl residues by facilitating synchronized proton transfers.
Topics: Aminoacyltransferases; Animals; Cyclization; Drosophila melanogaster; Glutamine; Phosphates; Protons; Pyrrolidonecarboxylic Acid | 2015 |
Stable isotope dilution HILIC-MS/MS method for accurate quantification of glutamic acid, glutamine, pyroglutamic acid, GABA and theanine in mouse brain tissues.
Topics: Animals; Brain; Chromatography, Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hydrophobic and Hydrophilic Interactions; Male; Mice; Pyrrolidonecarboxylic Acid; Tandem Mass Spectrometry | 2016 |
Influence of l-pyroglutamic acid on the color formation process of non-enzymatic browning reactions.
Topics: Alanine; Glucose; Glutamine; Maillard Reaction; Pyrrolidonecarboxylic Acid | 2017 |
Novel side reaction accompanying cyclization of Glu(R1)-Glu(R2) dipeptides via lactamization of the Glu(R1) residue.
Topics: Cyclization; Diketopiperazines; Dipeptides; Glutamine; Molecular Structure; Pyrrolidonecarboxylic Acid | 2018 |
Cyclization of N-Terminal Glutamic Acid to pyro-Glutamic Acid Impacts Monoclonal Antibody Charge Heterogeneity Despite Its Appearance as a Neutral Transformation.
Topics: Antibodies, Monoclonal; Cyclization; Glutamic Acid; Glutamine; Pyrrolidonecarboxylic Acid | 2019 |
Synthesis of α-Ketoglutaramic acid.
Topics: Amidohydrolases; Aminohydrolases; Animals; Catalysis; Glutamates; Glutamine; Ketoglutaric Acids; L-Amino Acid Oxidase; Pyrrolidonecarboxylic Acid; Snake Venoms | 2020 |
Metabolomics and psychological features in fibromyalgia and electromagnetic sensitivity.
Topics: Adult; Biomarkers; Caproates; Case-Control Studies; Choline; Female; Fibromyalgia; Glutamine; Glycine; Humans; Isoleucine; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Multivariate Analysis; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Pyrrolidonecarboxylic Acid | 2020 |
Effects of sevoflurane anesthesia and abdominal surgery on the systemic metabolome: a prospective observational study.
Topics: Abdomen; Anesthesia, General; Anesthetics, Inhalation; Citric Acid; Female; Glucose; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Middle Aged; Prospective Studies; Pyrrolidonecarboxylic Acid; Selenocysteine; Sevoflurane; Sphingosine; Sucrose | 2021 |
Bloodstain Metabolite Markers: Discovery and Validation for Estimating Age of Bloodstain within 7 Days.
Topics: Acetylcarnitine; Adenosine; Blood Stains; Forensic Medicine; Glutamine; Pyrrolidonecarboxylic Acid | 2022 |
Mendelian Randomization Study on Causal Association of Pyroglutamine with COVID-19.
Topics: COVID-19; Genome-Wide Association Study; Glutamine; Humans; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide; Pyrrolidonecarboxylic Acid | 2022 |
The intermediate in a nitrate-responsive ω-amidase pathway in plants may signal ammonium assimilation status.
Topics: Ammonium Compounds; Glutamine; Nitrates; Plants; Pyrrolidonecarboxylic Acid | 2023 |
High yield expression and purification of full-length Neurotensin with pyroglutamate modification.
Topics: Animals; Glutamine; Mammals; Neurotensin; Peptides; Pyrrolidonecarboxylic Acid | 2023 |
Predisposition to atherosclerosis in children and adults with trisomy 21: biochemical and metabolomic studies.
Topics: Acetates; Adolescent; Adult; Apolipoprotein A-I; Apolipoproteins B; Atherosclerosis; Cardiovascular Diseases; Child; Creatinine; Down Syndrome; Formates; Glutamine; Humans; Lysine; Proline; Pyrrolidonecarboxylic Acid; Risk Factors; Xanthines | 2023 |