pyrrolidine dithiocarbamate has been researched along with pd 98059 in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 14 (60.87) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, NF; Chuang, SK; Lee, YJ; Lin, WL; Tseng, TH | 1 |
| Khan, M; Namboodiri, AM; Pahan, K; Sheikh, FG; Singh, I | 1 |
| Bonner, JC; Lindroos, PM; Rice, AB; Wang, YZ | 1 |
| Beyerle, A; Krautmacher, C; Meves, A; Peus, D; Pittelkow, MR; Vasa, RA | 1 |
| Kinpara, K; Kondo, A; Mogi, M; Togari, A | 1 |
| Dehnade, F; Li, WQ; Zafarullah, M | 1 |
| Mulcahy, RT; Zipper, LM | 1 |
| Jung, HC; Kim, JM; Kim, JS; Song, IS | 1 |
| Awad, S; Igawa, K; Minatohara, K; Miyazaki, Y; Nishioka, K; Satoh, T; Yokozeki, H | 1 |
| Choi, BK; Kim, HH; Kwon, BS; Lee, HW; Nam, KO; Park, SJ | 1 |
| Borriello, A; Criniti, V; Cucciolla, V; Della Ragione, F; Indaco, S; Zappia, V | 1 |
| Hara, A; Hatakeyama, D; Hirade, K; Hotta, K; Ito, H; Kanamori, Y; Katayama, M; Kato, K; Kozawa, O; Matsuno, H; Mori, H; Niwa, M; Uematsu, T | 1 |
| Dai, J; Remick, DG; Wang, X; Zeng, X | 1 |
| Cho, ML; Kim, HY; Kim, KW; Lee, SH; Park, MK; Park, SH; Yoon, CH | 1 |
| Kim, HK; Kim, HS; Kim, HY; Kim, JR | 1 |
| Costanzo, C; Dalla Pozza, E; Donadelli, M; Palmieri, M; Piacentini, P; Scarpa, A; Scupoli, MT | 1 |
| Bark, H; Choi, CH; Chung, JM; Kim, SH; Park, EK | 1 |
| Deng, Z; Qiu, H; Wu, Y; You, X; Yu, M; Zeng, Y | 1 |
| Raddatzc, D; Ramadori, G; Sunil, Y | 1 |
| Fujita, T; Kajiya, M; Kanbara, K; Kawaguchi, H; Kittaka, M; Komatsuzawa, H; Kurihara, H; Ouhara, K; Shiba, H; Takeda, K | 1 |
| Chen, G; Han, F; Li, L; Tang, X; Wang, F; Zhou, W | 1 |
| Ho, SP; Hui, WS; Lo, PL; Mak, JC; Wong, AT | 1 |
| Jiang, R; Wang, L; Wei, L; Wu, J; Zhu, M | 1 |
23 other study(ies) available for pyrrolidine dithiocarbamate and pd 98059
| Article | Year |
|---|---|
Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Neoplasm Invasiveness; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured | 2012 |
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
Topics: Acetylcysteine; Alkyl and Aryl Transferases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Ceramides; Cytokines; Drug Interactions; Enzyme Induction; Flavonoids; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase Inhibitors; Pyrrolidines; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Thiocarbamates | 1998 |
Role of nuclear factor-kappa B and mitogen-activated protein kinase signaling pathways in IL-1 beta-mediated induction of alpha-PDGF receptor expression in rat pulmonary myofibroblasts.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Fibroblasts; Flavonoids; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Protein Binding; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrrolidines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha; Up-Regulation | 1998 |
UVB activates ERK1/2 and p38 signaling pathways via reactive oxygen species in cultured keratinocytes.
Topics: Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Hydrogen Peroxide; Intracellular Fluid; Keratinocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Ultraviolet Rays | 1999 |
Anti-apoptotic action of nerve growth factor in mouse osteoblastic cell line.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cytokines; DNA Fragmentation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Mice; Nerve Growth Factor; NF-kappa B; Osteoblasts; Pyridines; Pyrrolidines; Receptor, trkA; Receptor, trkB; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiocarbamates | 2000 |
Thiol antioxidant, N-acetylcysteine, activates extracellular signal-regulated kinase signaling pathway in articular chondrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Free Radical Scavengers; Glutathione; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates; Time Factors | 2000 |
Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes.
Topics: Cell Line; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Humans; Imidazoles; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Protein Binding; Pyridines; Pyrrolidines; Thiocarbamates; Trans-Activators; Transcription, Genetic; Transcriptional Activation | 2000 |
Expression of cyclooxygenase-2 in human neutrophils activated by Helicobacter pylori water-soluble proteins: possible involvement of NF-kappaB and MAP kinase signaling pathway.
Topics: Bacterial Proteins; Cyclooxygenase 2; Enzyme Inhibitors; Flavonoids; Helicobacter pylori; Imidazoles; Isoenzymes; Mitogen-Activated Protein Kinase Kinases; Neutrophils; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Pyridines; Pyrrolidines; Signal Transduction; Thiocarbamates; Transcription, Genetic; Up-Regulation | 2001 |
Glucocorticoids induced the production and gene expression of IL-1alpha through AP-1 and partially NF-kappaB activation in murine epidermal cells.
Topics: Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoresis, Agar Gel; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrocortisone; Imidazoles; Interleukin-1; Interleukin-6; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2002 |
4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.
Topics: 4-1BB Ligand; Animals; Antibodies, Monoclonal; Antigens, CD; Apoptosis; bcl-X Protein; CD8-Positive T-Lymphocytes; Cell Division; Cell Survival; Chromones; Flavonoids; Gene Expression Regulation; Ligands; Lymphocyte Activation; Male; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred BALB C; Minor Histocompatibility Antigens; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Receptors, Nerve Growth Factor; Receptors, Tumor Necrosis Factor; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor Receptor Superfamily, Member 9; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Antioxidants induce different phenotypes by a distinct modulation of signal transduction.
Topics: Antioxidants; Apoptosis; DNA-Binding Proteins; DNA, Complementary; Early Growth Response Protein 1; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Models, Chemical; Phenotype; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Pyrrolidines; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Thiocarbamates; Time Factors; Transcription Factors; Up-Regulation | 2002 |
Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Heat-Shock Proteins; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophils; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins | 2003 |
Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis.
Topics: Adult; Aged; Androstadienes; Antibodies, Monoclonal; Arthritis, Rheumatoid; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Chemokines; Chromones; Cytokines; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Interleukin-17; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Morpholines; NF-kappa B; Osteoarthritis; Phosphatidylinositol 3-Kinases; Phytohemagglutinins; Proto-Oncogene Proteins c-akt; Pyridines; Pyrrolidines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiocarbamates; Wortmannin | 2005 |
Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages.
Topics: Animals; Blotting, Northern; Chemokine CXCL1; Chemokines, CXC; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Flavonoids; Gene Expression; Hypoglycemic Agents; Immunologic Factors; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; PPAR gamma; Prostaglandin D2; Pyrrolidines; RNA Stability; RNA, Messenger; Specific Pathogen-Free Organisms; Thiazolidinediones; Thiocarbamates; Time Factors; Up-Regulation | 2005 |
Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA Primers; Fibroblasts; Flavonoids; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoblotting; Mice; Oligonucleotides, Antisense; Pancreatic Neoplasms; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; Thiocarbamates | 2006 |
Elevated reactive oxygen species but not glutathione regulate mercury resistance to AML-2/DX100 cells.
Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Imidazoles; Mercuric Chloride; Multidrug Resistance-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Probenecid; Pyridines; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates | 2006 |
Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells.
Topics: Anthracenes; Bacterial Proteins; Blotting, Western; DNA; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Monocytes; Mycoplasma genitalium; NF-kappa B; Protein Binding; Pyridines; Pyrrolidines; Thiocarbamates; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2008 |
Influence of NFkappaB inhibitors on IL-1beta-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC.
Topics: Caco-2 Cells; Chemokine CXCL10; Dexamethasone; Epithelial Cells; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glucocorticoids; HT29 Cells; Humans; Imidazoles; Interleukin-1beta; Interleukin-8; Intestines; NF-kappa B; Nitriles; Pyridines; Pyrrolidines; Receptors, Glucocorticoid; RNA, Messenger; Sulfones; Thiocarbamates | 2010 |
Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cells.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Calcium-Calmodulin-Dependent Protein Kinases; Cathelicidins; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; eIF-2 Kinase; Flavonoids; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Neovascularization, Physiologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Phosphorylation; Protein Kinase Inhibitors; Pyrrolidines; Regeneration; Signal Transduction; Thiocarbamates; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
[Effect of MAPK/NF-kappaB signaling pathway on extracellular release of HMGB1 induced by hypoxia in laryngeal Hep-2 carcinoma cells].
Topics: Anthracenes; Cell Hypoxia; Cell Line, Tumor; Flavonoids; HMGB1 Protein; Humans; Imidazoles; MAP Kinase Signaling System; NF-kappa B; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates | 2013 |
Cellular signalling pathways of matrix metalloproteinase gene expression by Pseudomonas aeruginosa-infected human bronchial epithelial cells.
Topics: Anthracenes; Bronchi; Cells, Cultured; Epithelial Cells; Flavonoids; Gene Expression; Humans; Interleukin-8; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrrolidines; RNA, Messenger; Thiocarbamates | 2014 |
Aspirin Inhibits LPS-Induced Expression of PI3K/Akt, ERK, NF-κB, CX3CL1, and MMPs in Human Bronchial Epithelial Cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchi; Cell Line; Chemokine CX3CL1; Chromones; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Lipopolysaccharides; Matrix Metalloproteinase 12; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidines; Respiratory Mucosa; Thiocarbamates | 2016 |