pyrrolidine dithiocarbamate has been researched along with fluorouracil in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kastan, MB | 1 |
| Beauchamp, RD; Brockman, JA; Chinery, R; Coffey, RJ; Peeler, MO; Shyr, Y | 1 |
| Bach, SP; Chinery, R; Coffey, RJ; O'Dwyer, ST; Potten, CS; Watson, AJ | 1 |
| Bach, SP; O'Dwyer, ST; Potten, CS; Watson, AJ; Williamson, SE | 1 |
4 other study(ies) available for pyrrolidine dithiocarbamate and fluorouracil
| Article | Year |
|---|---|
To oxidize or not to oxidize?
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; DNA-Binding Proteins; Doxorubicin; Fluorouracil; G1 Phase; Humans; Nuclear Proteins; Oxidation-Reduction; Proto-Oncogene Proteins p21(ras); Pyrrolidines; Thiocarbamates; Transcription Factors; Tumor Cells, Cultured; Vitamin E | 1997 |
Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Doxorubicin; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Humans; Nuclear Proteins; Pyrrolidines; Thiocarbamates; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E | 1997 |
Pyrrolidinedithiocarbamate increases the therapeutic index of 5-fluorouracil in a mouse model.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Colon; Drug Interactions; Fluorouracil; Intestine, Small; Mice; Mice, Inbred Strains; Mitosis; Pyrrolidines; Thiocarbamates | 2000 |
Regional localisation of p53-independent apoptosis determines toxicity to 5-fluorouracil and pyrrolidinedithiocarbamate in the murine gut.
Topics: Animals; Antioxidants; Apoptosis; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Antagonism; Drug Synergism; Fluorouracil; Intestinal Mucosa; Intestine, Large; Intestine, Small; Mice; Mice, Knockout; Mitosis; Organ Specificity; Pyrrolidines; Thiocarbamates; Time Factors; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2006 |