Page last updated: 2024-08-24

pyrrolidine dithiocarbamate and curcumin

pyrrolidine dithiocarbamate has been researched along with curcumin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's11 (52.38)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cong, W; Hou, GG; Li, N; Wang, CH; Xin, WY; Yao, BR1
Chen, SL; Cong, W; Hou, GG; Sun, Y; Suo, HD; Wang, CH; Wei, H; Xin, WY; Yao, BR; Zhang, YL; Zhao, F1
Hanazawa, S; Iwahashi, H; Kitano, S; Ozaki, K; Takeda, H1
Kondo, A; Koshihara, Y; Mogi, M; Togari, A1
Delaive, E; Raes, M; Remacle, J; Renard, P; Van Steenbrugge, M1
Kondo, A; Koshihara, Y; Togari, A1
Li, WQ; Liacini, A; Sylvester, J; Zafarullah, M1
Gangloff, SC; Grandjean-Laquerriere, A; Guenounou, M; Hornebeck, W; Le Naour, R; Trentesaux, C1
Demedts, MG; Dupont, LJ; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA1
Koj, A; Witek-Zawada, B1
Huang, WT; Lee, JJ; Liao, JF; Lin, MT; Shao, DZ1
Caruelle, JP; Cebrian, J; Ferry, A; Martelly, I; Vignaud, A1
Ma, I; Ma, TY; Ye, D1
Al-Sadi, RM; Ma, TY1
Kawakami, T; Kirita, T; Morisugi, T; Tanaka, Y1
Gatsinzi, T; Iverfeldt, K1
Deckard, LA; Logsdon, NJ; Sontheimer, H; Spiller, SE1
Ahmad, R; Chaudry, A; El Mabrouk, M; Sylvester, J; Zafarullah, M1
Chen, HX; Hu, LN; Li, JK; Peng, X; Xie, LX1
Chen, Z; Li, J; Wang, P; Ying, J; Yu, S1
Chen, Y; Geng, S; Jiang, Y; Li, X; Li, Y; Meng, Y; Wang, S; Wang, X; Wu, J; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, W1

Other Studies

21 other study(ies) available for pyrrolidine dithiocarbamate and curcumin

ArticleYear
N-phenylsulfonyl-3,5-bis(arylidene)-4-piperidone derivatives as activation NF-κB inhibitors in hepatic carcinoma cell lines.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Lipopolysaccharides; Mice; Molecular Docking Simulation; Molecular Structure; NF-kappa B; Pyridines; RAW 264.7 Cells; Structure-Activity Relationship

2018
Dissymmetric pyridyl-substituted 3,5-bis(arylidene)-4-piperidones as anti-hepatoma agents by inhibiting NF-κB pathway activation.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Heterografts; Humans; Liver Neoplasms, Experimental; Mice; NF-kappa B; Piperidones; Structure-Activity Relationship

2019
NF-kappaB inhibitors stimulate apoptosis of rabbit mature osteoclasts and inhibit bone resorption by these cells.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Animals; Apoptosis; Bone Resorption; Cells, Cultured; Curcumin; Gliotoxin; Mice; NF-kappa B; Osteoblasts; Pyrrolidines; Rabbits; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone

1997
Signal transduction system for interleukin-6 and interleukin-11 synthesis stimulated by epinephrine in human osteoblasts and human osteogenic sarcoma cells.
    Biochemical pharmacology, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antioxidants; Curcumin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epinephrine; Gene Expression; Humans; Interleukin-11; Interleukin-6; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoblasts; Osteosarcoma; Protein Kinase C; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thiocarbamates; Transcription Factor AP-1; Tumor Cells, Cultured

2001
Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?
    Antioxidants & redox signaling, 2001, Volume: 3, Issue:2

    Topics: Antioxidants; Binding Sites; Blotting, Western; Cells, Cultured; Curcumin; Enzyme Inhibitors; Ethylmaleimide; Fibroblasts; Glutathione; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-1; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates

2001
Signal transduction system for interleukin-6 synthesis stimulated by lipopolysaccharide in human osteoblasts.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2001, Volume: 21, Issue:11

    Topics: Adult; Cell Line; Curcumin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Interleukin-6; Kinetics; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoblasts; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured

2001
Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes.
    Matrix biology : journal of the International Society for Matrix Biology, 2002, Volume: 21, Issue:3

    Topics: Animals; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Collagenases; Curcumin; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Femur Head; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Osteoarthritis, Hip; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; Thiocarbamates; Time Factors; Transcription Factor AP-1

2002
Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes.
    Cytokine, 2002, May-07, Volume: 18, Issue:3

    Topics: Base Sequence; Cell Line; Curcumin; Cytokines; DNA; Gene Expression; Humans; Interleukin-10; Interleukin-6; Interleukin-8; Keratinocytes; NF-kappa B; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Ultraviolet Rays

2002
Involvement of p38 MAPK, JNK, p42/p44 ERK and NF-kappaB in IL-1beta-induced chemokine release in human airway smooth muscle cells.
    Respiratory medicine, 2003, Volume: 97, Issue:7

    Topics: Asthma; Blotting, Northern; Butadienes; Cells, Cultured; Chemokine CCL11; Chemokine CCL2; Chemokine CCL7; Chemokines; Chemokines, CC; Curcumin; Cytokines; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Immunoblotting; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocyte Chemoattractant Proteins; Muscle, Smooth; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; Stimulation, Chemical; Thiocarbamates

2003
Regulation of expression of stromyelysin-1 by proinflammatory cytokines in mouse brain astrocytes.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2003, Volume: 54, Issue:4

    Topics: Animals; Astrocytes; Brain; Brain Chemistry; Cell Culture Techniques; Curcumin; Cytokines; Drug Synergism; Epidermal Growth Factor; Gene Expression Regulation; Inflammation Mediators; Interferon-gamma; Interleukin-1; Matrix Metalloproteinase 3; Mice; NF-kappa B; Pyrrolidines; RNA, Messenger; Sesquiterpenes; Thiocarbamates; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2003
Blocking NF-kappaB activation may be an effective strategy in the fever therapy.
    The Japanese journal of physiology, 2003, Volume: 53, Issue:5

    Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antibodies, Monoclonal; Curcumin; Cytokines; Fever; Humans; Injections, Intravenous; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Male; NF-kappa B; Pyridines; Pyrrolidines; Rabbits; Thiocarbamates; Thiones; Time Factors; Tumor Necrosis Factor-alpha

2003
Effect of anti-inflammatory and antioxidant drugs on the long-term repair of severely injured mouse skeletal muscle.
    Experimental physiology, 2005, Volume: 90, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Curcumin; Cyclooxygenase Inhibitors; Diclofenac; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Indomethacin; Male; Mice; Muscle Contraction; Muscle, Skeletal; NF-kappa B; Pyrrolidines; Regeneration; Thiocarbamates

2005
Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:3

    Topics: Caco-2 Cells; Cell Membrane Permeability; Curcumin; Humans; I-kappa B Proteins; Myosin-Light-Chain Kinase; NF-kappa B; Promoter Regions, Genetic; Pyrrolidines; RNA Interference; Thiocarbamates; Tight Junctions; Tumor Necrosis Factor-alpha; Up-Regulation

2006
IL-1beta causes an increase in intestinal epithelial tight junction permeability.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Apr-01, Volume: 178, Issue:7

    Topics: Apoptosis; Caco-2 Cells; Curcumin; Humans; Interleukin-1beta; Intestinal Mucosa; Membrane Proteins; NF-kappa B; Occludin; Permeability; Pyrrolidines; RNA, Messenger; Thiocarbamates; Tight Junctions

2007
Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells.
    Journal of biochemistry, 2010, Volume: 147, Issue:5

    Topics: Acetylcysteine; Animals; Cells, Cultured; Curcumin; Cyclooxygenase 2; Free Radical Scavengers; Gene Expression Regulation; Isoquinolines; Leupeptins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Piperidines; Poly Adenosine Diphosphate Ribose; Pyrrolidines; Rabbits; Stress, Mechanical; Structure-Activity Relationship; Synovial Membrane; Thiocarbamates

2010
Sensitization to TRAIL-induced apoptosis in human neuroblastoma SK-N-AS cells by NF-κB inhibitors is dependent on reactive oxygen species (ROS).
    Journal of neuro-oncology, 2011, Volume: 104, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Curcumin; Diterpenes, Kaurane; Drug Resistance, Neoplasm; Humans; Neuroblastoma; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; TNF-Related Apoptosis-Inducing Ligand

2011
Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo.
    BMC cancer, 2011, Apr-14, Volume: 11

    Topics: Animals; Boronic Acids; Bortezomib; Cell Growth Processes; Cell Line, Tumor; Cerebellar Neoplasms; Curcumin; Ditiocarb; Humans; I-kappa B Proteins; Medulloblastoma; Mice; Mice, Inbred C57BL; Mice, Nude; NF-kappa B; Pyrazines; Pyrrolidines; Signal Transduction; Sulfasalazine; Thiocarbamates; Transgenes; Tumor Burden; Xenograft Model Antitumor Assays

2011
Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 30, Issue:3

    Topics: Anthracenes; Butadienes; Cartilage, Articular; Cells, Cultured; Chondrocytes; Curcumin; Endopeptidases; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipoxygenases; Masoprocol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1

2012
[Effects of NF-kappaB inhibitor on cisplatin-induced apoptosis in cervical cancer].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2013, Volume: 44, Issue:1

    Topics: Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Curcumin; Female; Humans; NF-kappa B; Pyrrolidines; Sulindac; Thiocarbamates; Uterine Cervical Neoplasms

2013
Curcumin Attenuates Retinal Vascular Leakage by Inhibiting Calcium/Calmodulin-Dependent Protein Kinase II Activity in Streptozotocin-Induced Diabetes.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Curcumin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Ependymoglial Cells; Gene Expression Regulation; Glucose; Intercellular Adhesion Molecule-1; Male; NF-kappa B; Nitric Oxide Synthase Type II; Primary Cell Culture; Pyrrolidines; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Signal Transduction; Sulfonamides; Thiocarbamates; Vascular Endothelial Growth Factor A

2016
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Anthracenes; Benzhydryl Compounds; Cell Line; Curcumin; Enzyme Activation; Humans; Imidazoles; Inflammation; Insulin Resistance; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phenols; Pyridines; Pyrrolidines; Thiocarbamates

2018