pyrrolidine dithiocarbamate has been researched along with acetylcysteine in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 40 (37.04) | 18.2507 |
| 2000's | 51 (47.22) | 29.6817 |
| 2010's | 16 (14.81) | 24.3611 |
| 2020's | 1 (0.93) | 2.80 |
| Authors | Studies |
|---|---|
| Baeuerle, PA; Caselmann, WH; Hofschneider, PH; Meyer, M; Schlüter, V; Schreck, R | 1 |
| Erl, W; Pietsch, A; Ströbel, M; Weber, C; Weber, PC; Ziegler-Heitbrock, HW | 1 |
| Brisseau, GF; Cheung, PY; Christie, N; Dackiw, AP; Rotstein, OD | 1 |
| Chambers, TJ; Fuller, K; Hall, TJ; Jeker, H; Schaeublin, M | 1 |
| Egawa, K; Nose, K; Yoshiwara, M | 1 |
| Bessho, R; Hirota, H; Kawai, M; Kubota, M; Kuwakado, K; Lin, YW; Matsubara, K; Nishikomori, R; Okuda, A; Wakazono, Y | 1 |
| Baraban, JM; Hardwick, JM; Lee, SH; Lin, KI; Narayanan, R; Ratan, RR | 1 |
| Abraham, NG; Laniado-Schwartzman, M; Stoltz, RA | 1 |
| Cooke, C; Haber, E; Hsieh, CM; Jain, M; Lee, ME; Lee, WS; Patterson, C; Perrella, MA; Schlegel, R; Tsai, JC; Wang, H; Yoshizumi, M | 1 |
| Allouche, M; Bailly, JD; Bordier, C; Come, MG; Duchayne, E; Laurent, G; Mansat, V; Quillet-Mary, A | 1 |
| Daniel, V; Pinkus, R; Weiner, LM | 1 |
| Alfranca, A; Aragonés, J; Castellanos, MC; de Landázuri, MO; Muñoz, C; Pascual-Salcedo, D; Redondo, JM; Vara, A | 1 |
| Bowie, A; O'Neill, LA | 1 |
| Ghosh, S; Phillips, RJ | 1 |
| Dimitrov, DS; Lowy, RJ | 1 |
| Li, DW; Spector, A | 1 |
| Gon, Y; Hashimoto, S; Hayashi, S; Horie, T; Maruoka, S; Nakayama, T; Yodoi, J; Yoshida, S | 1 |
| Hainaut, P; Richard, MJ; Verhaegh, GW | 1 |
| Beauchamp, RD; Brockman, JA; Chinery, R; Coffey, RJ; Peeler, MO; Shyr, Y | 1 |
| Namboodiri, AM; Pahan, K; Sheikh, FG; Singh, I | 1 |
| Khan, M; Namboodiri, AM; Pahan, K; Sheikh, FG; Singh, I | 1 |
| Bacon, BR; Bellezzo, JM; Britton, RS; Bulla, GA; Fox, ES; Leingang, KA | 1 |
| Khan, M; Pahan, K; Singh, AK; Singh, I | 1 |
| Gon, Y; Hashimoto, S; Horie, T; Matsumoto, K; Nakayama, T; Takizawa, H | 1 |
| Bando, M; Kefer, J; Malik, AB; Niles, WD; Rahman, A | 1 |
| Adler, G; Schmid, RM; Steinle, AU; Wagner, M; Weidenbach, H | 1 |
| Grisham, MB | 1 |
| Desaki, M; Kasama, T; Kawasaki, S; Kobayashi, K; Kohyama, T; Kudoh, S; Matsushima, K; Nakahara, K; Ohtoshi, T; Takizawa, H; Yamamoto, K | 1 |
| Byrne, CH; Griffin, JD; Salgia, R; Sattler, M; Shrikhande, G; Verma, S; Winkler, T | 1 |
| Mohan, N; Mohan, S; Sprague, EA; Valente, AJ | 1 |
| Mukai, J; Nishikimi, A; Yamada, M | 1 |
| Harris, DC; Rangan, GK; Tay, YC; Wang, Y | 3 |
| Hanazawa, S; Imai, K; Takeshita, A | 1 |
| Delafontaine, P; Du, J; Peng, T; Scheidegger, KJ | 1 |
| Bettaïeb, A; Bezombes, C; D'orgeix, AD; Jaffrézou, JP; Laurent, G; Mansat-de Mas, V; Quillet-Mary, A | 1 |
| Huyck, HL; Khalak, R; Pryhuber, GS | 1 |
| Kaffenberger, W; Van Beuningen, D; Walther, M | 1 |
| Botteron, C; Dobbelaere, DA; Fernandez, PC; Heussler, VT; Machado, J; Palmer, GH | 1 |
| Abe, S; Kudoh, S; Sugawara, I; Takizawa, H | 1 |
| Bernasconi, S; Ghezzi, P; Mantovani, A; Orlando, S; Saccani, A; Saccani, S; Sica, A; Sironi, M | 1 |
| Haddad, JJ; Land, SC | 1 |
| Haddad, JJ; Land, SC; Olver, RE | 1 |
| Boulares, AH; Cohen, SD; Giardina, C; Inan, MS; Khairallah, EA | 1 |
| Choi, IW; Choi, JH; Chung, WJ; Han, SJ; Han, SS; IM, SY; Jang, KY; Lee, DG; Lee, HB; Lee, HK; Park, KH | 1 |
| Dehnade, F; Li, WQ; Zafarullah, M | 1 |
| Hayakawa, T; Iseki, A; Kambe, F; Niwata, S; Okumura, K; Seo, H; Yamamoto, R | 1 |
| Castranova, V; Hong, SM; Kang, JL; Lee, HS; Pack, IS | 1 |
| Higashi, Y; Kanekura, T; Kanzaki, T | 1 |
| Hayakawa, T; Iseki, A; Kambe, F; Okumura, K; Seo, H | 1 |
| Herman, TS; Martinez, BR; Meltz, ML; Mohan, S; Natarajan, M | 1 |
| Hennig, B; Kühn, H; Lee, YW; Neish, AS; Toborek, M | 1 |
| Han, B; Ji, B; Logsdon, CD | 1 |
| Chung, HY; Han, SI; Kang, HS; Kim, HD; Kim, SH; Oh, SY | 1 |
| Gon, Y; Hashimoto, S; Horie, T; Koura, T; Matsumoto, K; Nakayama, T; Takeshita, I | 1 |
| Aggarwal, BB; Shrivastava, A | 1 |
| Dörger, M; Krombach, F; Kupatt, C; Pepperl, S; Ringel, F | 1 |
| Desaki, M; Kasama, T; Kawasaki, S; Kobayashi, K; Nakahara, K; Ohtoshi, T; Okazaki, H; Sagai, M; Takami, K; Takizawa, H; Tanaka, M; Yamamoto, K | 1 |
| Korfhagen, TR; Whitsett, JA; Yoshida, M | 1 |
| Koch, AE; Morel, JC; Park, CC; Woods, JM | 1 |
| Gong, G; Siddiqui, A; Tanveer, R; Waris, G | 1 |
| Cabrini, G; Melotti, P; Nicolis, E; Pavirani, A; Rolfini, R; Tamanini, A | 1 |
| Entman, ML; Evans, AJ; Frangogiannis, NG; Lakshminarayanan, V; Lewallen, M; Michael, LH; Wedin, KE | 1 |
| Huh, KW; Siddiqui, A; Waris, G | 1 |
| Hozumi, A; Kotani, Y; Nishimura, Y; Nishiuma, T; Yokoyama, M | 1 |
| Bessho, T; Ohyama, K; Yamakawa, T; Yuan, B | 1 |
| Cross, AS; Farrance, IK; Hall, G; Hasday, JD; Rogers, TB; Singh, IS; Wright, G | 1 |
| Ashida, H; Danno, G; Fukuda, I; Hashizume, K; Hatanaka, Y; Sano, T; Suzuki, K; Tani, Y; Yamaguchi, Y | 1 |
| Bae, I; Bae, JH; Baek, WK; Cho, CH; Cho, JW; Kim, KM; Kwon, TK; Lee, JE; Park, JW; Song, DK; Suh, MH; Suh, SI | 1 |
| Carr, AC; Frei, B; Zhu, BZ | 1 |
| Rothstein, TL; Schram, BR | 1 |
| Chen, CJ; Liao, SL | 1 |
| Chang, WM; Huang, KL; Lai, MT; Lai, YK | 1 |
| Hayakawa, M; Karin, M; Kikugawa, K; Kitagawa, M; Miyashita, H; Sakamoto, I; Tanaka, H; Yasuda, H | 1 |
| Castranova, V; Hur, KC; Kang, JL; Lee, HS; Pack, IS | 1 |
| Shen, WH; Zhang, CY; Zhang, GY | 1 |
| Huang, WT; Lee, JJ; Liao, JF; Lin, MT; Shao, DZ | 1 |
| Clément, MV | 1 |
| Jana, M; Pahan, K | 1 |
| Khandelwal, S; Pathak, N | 1 |
| Chen, SX; Li, YQ; Ma, D; Ni, W; Xu, YJ; Yang, Z; Zhang, ZX | 1 |
| Costanzo, C; Dalla Pozza, E; Donadelli, M; Palmieri, M; Piacentini, P; Scarpa, A; Scupoli, MT | 1 |
| Bark, H; Choi, CH; Chung, JM; Kim, SH; Park, EK | 1 |
| Antoniak, S; Bogdanov, VY; Borchert, HH; Goldin-Lang, P; Pels, K; Rauch, U; Rosenthal, P; Schultheiss, HP; Szotowski, B; Tran, QV | 1 |
| Jóźwiak, Z; Kania, K; Zych, A | 1 |
| Liu, SH; Tzeng, HP; Ueng, TH; Yang, RS | 1 |
| Araki, S; Dobashi, K; Kawagoe, R; Kubo, K; Shirahata, A; Yamamoto, Y | 1 |
| Buckley, M; Krakauer, T | 1 |
| Antonicelli, F; Garnotel, R; Gillery, P; Nguyen, P; Poitevin, S | 1 |
| Hu, W; Ni, W; Xie, J; Xu, Y; Yang, S; Zhao, J | 1 |
| Kawakami, T; Kirita, T; Morisugi, T; Tanaka, Y | 1 |
| Adelibieke, Y; Adijiang, A; Bolati, D; Enomoto, A; Higashiyama, Y; Higuchi, Y; Muteliefu, G; Nishijima, F; Niwa, T; Shimizu, H | 1 |
| Choi, HJ; Shim, JK; Song, JH | 1 |
| Jiang, C; Liu, H; Ruan, J; Xiong, C | 1 |
| Fu, Z; Guan, L; Hu, Z; Huang, J; Li, X; Li, Z; Liu, H | 1 |
| Ding, L; Dong, F; Du, Q; Huang, Y; Song, X; Tong, D; Zhang, H; Zhang, W; Zhao, X | 1 |
| Huang, D; Liu, X; Nie, S; Xie, M | 1 |
| Deng, Q; Ding, H; Li, D; Li, X; Li, Y; Liu, G; Shi, X; Song, Y; Wang, J; Wang, Z; Yin, L; Zhang, Y | 1 |
| Chen, MC; Du, JY; Huang, CH; Lee, CF; Lee, YJ; Lin, TH; Shen, HJ; Wang, JH; Wu, YY | 1 |
| Aljada, A; Aziz, MA; El-Abadelah, MM; Nasr, A; Sabri, SS; Saleh, AM; Zahra, JA | 1 |
| Li, Z; Wei, M; Xiao, L; Yang, Z | 1 |
| Li, Y; Xu, G; Yang, P | 1 |
| Ahn, G; Cho, SH; Eom, CY; Heo, SJ; Jeon, YJ; Jeong, MS; Kim, KN; Kim, SY; Ko, EY; Kwon, SH; Lee, KP; Lee, W | 1 |
| Gedanken, A; Li, C; Li, X; Lin, X; Liu, X; Qiao, G; Xu, H; Yuan, R | 1 |
| Feng, J; Ge, CX; Gu, TT; Hu, LF; Huang, P; Li, Q; Lou, DS; Qin, YT; Tan, J; Xu, MX | 1 |
| Li, Q; Wang, L; Xu, X; Xu, Y; Yang, F; Yin, Z; Zhang, Q | 1 |
| Ji, Y; Li, D; Lu, Y; Rong, X; Sun, Y | 1 |
108 other study(ies) available for pyrrolidine dithiocarbamate and acetylcysteine
| Article | Year |
|---|---|
Hepatitis B virus transactivator MHBst: activation of NF-kappa B, selective inhibition by antioxidants and integral membrane localization.
Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Blotting, Western; Cell Line; Cell Membrane; Chloramphenicol O-Acetyltransferase; Fluorescent Antibody Technique; HeLa Cells; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Protein Kinase C; Pyrrolidines; Recombinant Fusion Proteins; Thiocarbamates; Trans-Activators; Transfection | 1992 |
Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-kappa B mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Biological Transport; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Endothelium, Vascular; Humans; Molecular Sequence Data; Monocytes; NF-kappa B; Oligonucleotide Probes; Polymerase Chain Reaction; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1994 |
Posttranscriptional regulation of macrophage tissue factor expression by antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Female; Fluorescent Antibody Technique; Free Radical Scavengers; Gene Expression Regulation; Humans; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Monocytes; NF-kappa B; Pyrrolidines; RNA Processing, Post-Transcriptional; RNA, Messenger; Thiocarbamates; Thromboplastin; Transcription Factor AP-1; Transcription Factors | 1995 |
The role of reactive oxygen intermediates in osteoclastic bone resorption.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Bone Resorption; Cell Survival; Cells, Cultured; Deferoxamine; Free Radical Scavengers; NF-kappa B; Osteoclasts; Pyrrolidines; Rats; Reactive Oxygen Species; Thiocarbamates | 1995 |
Effect of radical scavengers on TNF alpha-mediated activation of the uPA in cultured cells.
Topics: Acetylcysteine; Animals; Cell Line, Transformed; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Mice; Microscopy, Confocal; Oxidation-Reduction; Pyrrolidines; RNA, Messenger; Thiocarbamates; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator | 1994 |
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
Topics: Acetylcysteine; Apoptosis; Base Sequence; Cytarabine; Endonucleases; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phenanthrolines; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Thymus Gland; Tumor Cells, Cultured | 1994 |
Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B.
Topics: Acetylcysteine; Animals; Apoptosis; Base Sequence; Cell Nucleus; Chelating Agents; Dithiothreitol; DNA; Iron; Lipid Peroxidation; Male; Mercaptoethanol; Mice; Molecular Sequence Data; Neuroblastoma; NF-kappa B; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Sindbis Virus; Sulfhydryl Reagents; Thiocarbamates; Tumor Cells, Cultured | 1995 |
The role of NF-kappaB in the angiogenic response of coronary microvessel endothelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylcysteine; Alkaloids; Animals; Antioxidants; Base Sequence; Butylated Hydroxyanisole; Capillaries; Cell Nucleus; Cells, Cultured; Consensus Sequence; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Kinetics; Microcirculation; Molecular Sequence Data; Naphthalenes; Neovascularization, Physiologic; NF-kappa B; Oligodeoxyribonucleotides; Protein Kinase C; Pyrrolidines; Rabbits; Staurosporine; Substrate Specificity; Thiocarbamates | 1996 |
Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Apoptosis; Cell Survival; Cells, Cultured; Chromatin; Culture Media, Serum-Free; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Epidermal Growth Factor; Fibroblast Growth Factor 2; Humans; Insulin; Kinetics; Male; Muscle, Smooth, Vascular; PC12 Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates; Time Factors | 1996 |
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines.
Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Differentiation; Daunorubicin; DNA Damage; DNA Nucleotidylexotransferase; DNA, Neoplasm; Free Radical Scavengers; Humans; Leukemia, Myeloid, Acute; Methionine Sulfoximine; Nucleosomes; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured; Verapamil | 1996 |
Role of oxidants and antioxidants in the induction of AP-1, NF-kappaB, and glutathione S-transferase gene expression.
Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Butylated Hydroxyanisole; Catalase; Cell Line; Gene Expression; Glutathione; Glutathione Transferase; Humans; Hydroquinones; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Oxidants; Oxidative Stress; Pyrrolidines; Rats; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates; Transcription Factor AP-1 | 1996 |
Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: modulation of NF-kappa B and AP-1 transcription fac
Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Endothelium, Vascular; Free Radical Scavengers; Gene Expression Regulation; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; NF-kappa B; Pyrrolidines; Thiocarbamates; Transcription Factor AP-1 | 1996 |
Studies into the mechanism of NF kappa B activation by IL1, TNF and H2O2 in primary and transformed endothelial cells.
Topics: Acetylcysteine; Allopurinol; Cell Line, Transformed; Cells, Cultured; Cyclic N-Oxides; Deferoxamine; DNA-Binding Proteins; Endothelium, Vascular; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-1; Kinetics; NF-kappa B; NF-KappaB Inhibitor alpha; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha; Umbilical Veins | 1997 |
Regulation of IkappaB beta in WEHI 231 mature B cells.
Topics: Acetylcysteine; Antioxidants; B-Lymphocytes; Biological Transport; Cell Line; Cell Nucleus; Chymotrypsin; Cysteine Proteinase Inhibitors; Cytosol; DNA; Enzyme Inhibitors; Feedback; Glycoproteins; Lipopolysaccharides; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Pyrrolidines; RNA, Messenger; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelB; Transcription Factors | 1997 |
Characterization of influenza virus-induced death of J774.1 macrophages.
Topics: Acetylcysteine; Amantadine; Animals; Antioxidants; Cell Death; Cell Division; Cell Line; Cell Membrane; Cytopathogenic Effect, Viral; DNA Fragmentation; Macrophages; Mice; Orthomyxoviridae; Pyrrolidines; Thiocarbamates; Ultraviolet Rays; Viral Proteins; Virus Replication | 1997 |
Hydrogen peroxide-induced expression of the proto-oncogenes, c-jun, c-fos and c-myc in rabbit lens epithelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Carcinogens; Cell Line; Epithelial Cells; Free Radical Scavengers; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Hydrogen Peroxide; Lens, Crystalline; Oxidants; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Pyrrolidines; Rabbits; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiocarbamates; Transcription Factor AP-1 | 1997 |
N-acetylcysteine attenuates TNF-alpha-dependent reduction of IL-4-induced Fc epsilon RII expression in human monocytes.
Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Free Radical Scavengers; Humans; Interleukin-4; Monocytes; Pyrrolidines; Receptors, IgE; Thiocarbamates; Tumor Necrosis Factor-alpha | 1997 |
Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper.
Topics: Acetylcysteine; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line; Chelating Agents; Copper; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA Damage; DNA-Binding Proteins; Humans; Hydrogen Peroxide; Intercalating Agents; Ion Transport; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Protein Binding; Protein Conformation; Protein Serine-Threonine Kinases; Proteins; Pyrrolidines; Thiocarbamates; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 1997 |
Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Doxorubicin; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Humans; Nuclear Proteins; Pyrrolidines; Thiocarbamates; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E | 1997 |
N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Astrocytes; Cells, Cultured; Cytokines; Enzyme Inhibitors; Lipopolysaccharides; Macrophages, Peritoneal; Neuroglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyrrolidines; Rats; Thiocarbamates; Tumor Cells, Cultured | 1998 |
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
Topics: Acetylcysteine; Alkyl and Aryl Transferases; Animals; Arginine; Astrocytes; Brain; Cells, Cultured; Ceramides; Cytokines; Drug Interactions; Enzyme Induction; Flavonoids; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase Inhibitors; Pyrrolidines; Rats; Signal Transduction; Sphingomyelin Phosphodiesterase; Thiocarbamates | 1998 |
Modulation of lipopolysaccharide-mediated activation in rat Kupffer cells by antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Nucleus; DNA-Binding Proteins; Kupffer Cells; Lipopolysaccharides; Liver Diseases; Macrophage Activation; Male; NF-kappa B; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tumor Necrosis Factor-alpha; Vitamin E | 1998 |
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
Topics: Acetylcysteine; Adrenoleukodystrophy; Amitrole; Animals; Antioxidants; Apoptosis; Brain; Cells, Cultured; Ceramides; Cytokines; Diamide; DNA Fragmentation; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Inflammation; Interleukin-1; Multiple Sclerosis; Oxidation-Reduction; Pyrrolidines; Rats; Reactive Oxygen Species; Sphingomyelins; Thiocarbamates; Tumor Necrosis Factor-alpha | 1998 |
N-acetylcysteine inhibits IL-1 alpha-induced IL-8 secretion by bronchial epithelial cells.
Topics: Acetylcysteine; Antioxidants; Bronchi; Butylated Hydroxyanisole; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Free Radical Scavengers; Humans; Interleukin-1; Interleukin-8; Pyrrolidines; Thiocarbamates | 1998 |
E-selectin expression in human endothelial cells by TNF-alpha-induced oxidant generation and NF-kappaB activation.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Binding Sites; Cell Nucleus; Cells, Cultured; E-Selectin; Endothelium, Vascular; Humans; NF-kappa B; Oligodeoxyribonucleotides; Oxidants; Pulmonary Artery; Pyrrolidines; Reactive Oxygen Species; Recombinant Proteins; Signal Transduction; Thiocarbamates; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1998 |
NF-kappaB/Rel activation in cerulein pancreatitis.
Topics: Acetylcysteine; Amylases; Animals; Antioxidants; Blotting, Northern; Blotting, Western; Ceruletide; DNA Probes; Dose-Response Relationship, Drug; Edema; Free Radical Scavengers; L-Lactate Dehydrogenase; Male; NF-kappa B; Pancreatitis; Pancreatitis-Associated Proteins; Protein Binding; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates | 1999 |
NF-kappaB activation in acute pancreatitis: protective, detrimental, or inconsequential?
Topics: Acetylcysteine; Acute Disease; Antioxidants; Cell Adhesion Molecules; Free Radical Scavengers; Humans; NF-kappa B; Pancreatitis; Pyrrolidines; Thiocarbamates | 1999 |
Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: importance in cytokine transcription.
Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Bronchi; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Gene Expression Regulation; Humans; Interleukin-8; NF-kappa B; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription, Genetic; Vehicle Emissions | 1999 |
Hematopoietic growth factors signal through the formation of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Cycle; Cell Line; Cell Survival; Culture Media, Conditioned; Genes, fos; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Hydrogen Peroxide; Interleukin-3; Kinetics; Megakaryocytes; Mercaptoethanol; Mice; Proto-Oncogene Proteins c-fos; Pyrrolidines; Reactive Oxygen Species; Recombinant Proteins; Signal Transduction; Stem Cell Factor; Thiocarbamates; Thrombopoietin | 1999 |
Regulation of low shear flow-induced HAEC VCAM-1 expression and monocyte adhesion.
Topics: Acetylcysteine; Antibodies; Antioxidants; Aorta; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Humans; Monocytes; NF-kappa B; Pyrrolidines; Rheology; Thiocarbamates; Vascular Cell Adhesion Molecule-1 | 1999 |
Nuclear translocation of nuclear factor kappa B in early 1-cell mouse embryos.
Topics: Acetylcysteine; Animals; Blastocyst; Cell Nucleus; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Development; Female; Male; Mice; Mice, Inbred ICR; Morphogenesis; NF-kappa B; Pregnancy; Pyrrolidines; Thiocarbamates | 1999 |
Inhibition of nuclear factor-kappaB activation reduces cortical tubulointerstitial injury in proteinuric rats.
Topics: Acetylcysteine; Animals; Cell Movement; Doxorubicin; Kidney; Kidney Cortex; Kidney Tubules; Lipid Peroxides; Macrophages; Male; Monocytes; Nephrosis; NF-kappa B; Proteinuria; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates; Time Factors | 1999 |
CpG motifs in Porphyromonas gingivalis DNA stimulate interleukin-6 expression in human gingival fibroblasts.
Topics: Acetylcysteine; Animals; Antioxidants; Consensus Sequence; CpG Islands; Deoxyribonucleases; DNA, Bacterial; Fibroblasts; Gene Expression; Gingiva; Humans; Interleukin-6; Mice; NF-kappa B; Porphyromonas gingivalis; Pyrrolidines; Thiocarbamates | 1999 |
Angiotensin II activation of insulin-like growth factor 1 receptor transcription is mediated by a tyrosine kinase-dependent redox-sensitive mechanism.
Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Calcium; Cells, Cultured; Genes, Reporter; Hydrogen Peroxide; Linoleic Acids; Muscle, Smooth, Vascular; Oxidation-Reduction; Protein-Tyrosine Kinases; Pyrrolidines; Rats; Receptor, IGF Type 1; Thiocarbamates; Transcription, Genetic | 1999 |
Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Ceramides; Daunorubicin; Drug Interactions; Electron Transport; Enzyme Activation; Free Radical Scavengers; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitochondria; Mitogen-Activated Protein Kinases; Pyrrolidines; Reactive Oxygen Species; Sphingomyelin Phosphodiesterase; Thiocarbamates; Transcription Factor AP-1; U937 Cells | 1999 |
Antagonistic effects of pyrrolidine dithiocarbamate and N-acetyl-L-cysteine on surfactant protein A and B mRNAs.
Topics: Acetylcysteine; Blotting, Northern; Carmustine; Cell Line; Clusterin; Drug Synergism; Epithelial Cells; Gene Expression Regulation; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glycoproteins; Humans; Hydrogen Peroxide; Lung; Molecular Chaperones; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Pyrrolidines; Ribonucleases; RNA, Messenger; Thiocarbamates | 1999 |
Influence of clinically used antioxidants on radiation-induced expression of intercellular cell adhesion molecule-1 on HUVEC.
Topics: Acetylcysteine; Antioxidants; Biological Assay; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Flow Cytometry; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Neutrophils; Pyrrolidines; Radiation Tolerance; Radiation-Protective Agents; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 1999 |
Inhibition of NFkappaB activation with antioxidants is correlated with reduced cytokine transcription in PTC.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Survival; Cytokines; Deferoxamine; Hydrogen Peroxide; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; NF-kappa B; Pyrrolidines; Quercetin; Rats; Rats, Wistar; Thiocarbamates; Transcription, Genetic | 1999 |
The inhibition of NF-kappaB activation pathways and the induction of apoptosis by dithiocarbamates in T cells are blocked by the glutathione precursor N-acetyl-L-cysteine.
Topics: Acetylcysteine; Activating Transcription Factor 2; Apoptosis; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line, Transformed; Cyclic AMP Response Element-Binding Protein; Disulfiram; DNA; DNA Primers; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Transcription Factors; Transcription, Genetic | 1999 |
Diesel exhaust (DE)-induced cytokine expression in human bronchial epithelial cells: a study with a new cell exposure system to freshly generated DE in vitro.
Topics: Acetylcysteine; Antioxidants; Bronchi; Cell Line, Transformed; Epithelial Cells; Free Radical Scavengers; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Pyrrolidines; RNA, Messenger; Thiocarbamates; Thymidine; Transforming Growth Factor beta; Tritium; Vehicle Emissions | 2000 |
Redox regulation of chemokine receptor expression.
Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Cell Movement; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Humans; Hydrogen Peroxide; Mercaptoethanol; Monocytes; Oxidation-Reduction; Pyrrolidines; Reactive Oxygen Species; Receptors, CCR2; Receptors, CCR4; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Interleukin; Receptors, Interleukin-8B; RNA, Messenger; Thiocarbamates; Time Factors | 2000 |
The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting.
Topics: Acetylcysteine; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Buthionine Sulfoximine; Dipeptides; DNA Fragmentation; Enzyme Inhibitors; Epithelium; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Models, Biological; NF-kappa B; Oxidation-Reduction; Oxygen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pulmonary Alveoli; Pyrrolidines; Sulfasalazine; Thiocarbamates | 2000 |
Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Fetus; Gene Expression Regulation; Glutathione; Glutathione Disulfide; Homeostasis; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Kinetics; NF-kappa B; Nuclear Proteins; Oxidants; Oxidation-Reduction; Pulmonary Alveoli; Pyrrolidines; Rats; Respiratory Mucosa; Thiocarbamates; Transcription Factors | 2000 |
Acetaminophen inhibits NF-kappaB activation by interfering with the oxidant signal in murine Hepa 1-6 cells.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Blotting, Western; Carcinoma, Hepatocellular; DNA Probes; DNA-Binding Proteins; Fluoresceins; Hydrogen Peroxide; I-kappa B Proteins; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Pyrrolidines; Signal Transduction; Thiocarbamates; Tumor Cells, Cultured | 2000 |
Selective involvement of reactive oxygen intermediates in platelet-activating factor-mediated activation of NF-kappaB.
Topics: Acetylcysteine; Animals; Antioxidants; Azepines; Benzoquinones; Disseminated Intravascular Coagulation; DNA-Binding Proteins; Female; Gene Expression Regulation; Genistein; Hemorrhage; Hydrogen Peroxide; I-kappa B Proteins; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Lethal Dose 50; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Platelet Activating Factor; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pulmonary Edema; Pyrrolidines; Quinones; Reactive Oxygen Species; Rifabutin; Serine Proteinase Inhibitors; Signal Transduction; Specific Pathogen-Free Organisms; Succinic Acid; Thiocarbamates; Tosylphenylalanyl Chloromethyl Ketone; Triazoles; Tumor Necrosis Factor-alpha; Vitamin E | 2000 |
Thiol antioxidant, N-acetylcysteine, activates extracellular signal-regulated kinase signaling pathway in articular chondrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Cysteine; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Free Radical Scavengers; Glutathione; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Reactive Oxygen Species; Sulfhydryl Compounds; Thiocarbamates; Time Factors | 2000 |
Pyrrolidine dithiocarbamate inhibits TNF-alpha-dependent activation of NF-kappaB by increasing intracellular copper level in human aortic smooth muscle cells.
Topics: Acetylcysteine; Antioxidants; Aorta; Cells, Cultured; Copper; Drug Antagonism; Free Radical Scavengers; Humans; Muscle, Smooth, Vascular; NF-kappa B; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha | 2000 |
Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages.
Topics: Acetylcysteine; Animals; Cell Line; Enzyme Inhibitors; Genistein; I-kappa B Proteins; Macrophage Activation; Macrophages; Mice; NF-kappa B; Protein Tyrosine Phosphatases; Pyrrolidines; Reactive Oxygen Species; Silicon Dioxide; Superoxide Dismutase; Thiocarbamates; Tyrphostins | 2000 |
Inhibitory effects of 9-cis-retinoic acid and pyrrolidinedithiocarbamate on cyclooxygenase (COX)-2 expression and cell growth in human skin squamous carcinoma cells.
Topics: Acetylcysteine; Alitretinoin; Antineoplastic Agents; Antioxidants; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Isoenzymes; Keratinocytes; Membrane Proteins; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Retinoids; Skin Neoplasms; Thiocarbamates; Time Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Regulation of thyroid follicular cell function by intracellular redox-active copper.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Division; Cell Line; Chelating Agents; Copper; DNA; DNA-Binding Proteins; Gene Expression; Hydrogen Peroxide; Iodide Peroxidase; Nuclear Proteins; Oxidation-Reduction; Paired Box Transcription Factors; PAX8 Transcription Factor; Phenanthrolines; Pyrrolidines; Rats; RNA, Messenger; Thiocarbamates; Thyroglobulin; Thyroid Gland; Thyroid Nuclear Factor 1; Trans-Activators; Transcription Factors; Tumor Suppressor Protein p53 | 2000 |
Cytokine gene expression in Adriamycin nephropathy: effects of antioxidant nuclear factor kappaB inhibitors in established disease.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Cytokines; Doxorubicin; Free Radical Scavengers; Kidney Diseases; Male; NF-kappa B; Nuclear Proteins; Pyrrolidines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiocarbamates | 2000 |
Antioxidant compounds interfere with the 3.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E | 2000 |
IL-4-induced oxidative stress upregulates VCAM-1 gene expression in human endothelial cells.
Topics: Acetylcysteine; Arteriosclerosis; Cells, Cultured; Endothelium, Vascular; Genes, Reporter; Humans; Inflammation; Interleukin-4; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Sp1 Transcription Factor; Thiocarbamates; Transcription Factors; Transcription, Genetic; Transfection; Umbilical Veins; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2001 |
CCK independently activates intracellular trypsinogen and NF-kappaB in rat pancreatic acinar cells.
Topics: Acetylcysteine; Animals; CHO Cells; Cholecystokinin; Cricetinae; Enzyme Inhibitors; Intracellular Membranes; Male; NF-kappa B; Pancreas; Pyrrolidines; Rats; Rats, Wistar; Thiocarbamates; Trypsin; Trypsinogen | 2001 |
Activation of heat shock factor 1 by pyrrolidine dithiocarbamate is mediated by its activities as pro-oxidant and thiol modulator.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibroblasts; Glutathione Disulfide; Heat Shock Transcription Factors; Heat-Shock Proteins; Oxidants; Propyl Gallate; Pyrrolidines; Sulfhydryl Compounds; Thiocarbamates; Transcription Factors | 2001 |
N-acetyl-L-cysteine inhibits bleomycin-induced interleukin-8 secretion by bronchial epithelial cells.
Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Antioxidants; Bleomycin; Bronchi; Cell Line; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Humans; Interleukin-8; Pyrrolidines; Respiratory Distress Syndrome; Respiratory Mucosa; Thiocarbamates | 2000 |
Antioxidants differentially regulate activation of nuclear factor-kappa B, activator protein-1, c-jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: evidence that JNK and NF-kappa B activation are not linked to apoptosis.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Hydroxyl Radical; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Mitogen-Activated Protein Kinases; NF-kappa B; Pyrrolidines; Superoxides; Thiocarbamates; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Hyperoxia upregulates the NO pathway in alveolar macrophages in vitro: role of AP-1 and NF-kappaB.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Hyperoxia; Macrophages, Alveolar; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Transcription Factor AP-1; Up-Regulation | 2001 |
Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells.
Topics: Acetylcysteine; Antioxidants; Benzene; Bronchi; Cell Line; Chemokine CCL5; Enzyme Inhibitors; Epithelial Cells; Free Radical Scavengers; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; In Vitro Techniques; Interleukin-8; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; RNA, Messenger; T-Lymphocytes; Thiocarbamates; Vehicle Emissions | 2001 |
Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Cells, Cultured; Enzyme Inhibitors; Glycoproteins; Lung; Macrophages, Alveolar; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout; NF-kappa B; Oxidants; Oxidation-Reduction; Oxidative Stress; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactants; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates | 2001 |
A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antioxidants; Arthritis, Rheumatoid; Cell Adhesion; E-Selectin; Endothelium, Vascular; Fibroblasts; HL-60 Cells; Humans; Intercellular Adhesion Molecule-1; Interleukin-18; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrrolidines; Signal Transduction; Synovial Fluid; Thiocarbamates; Vascular Cell Adhesion Molecule-1 | 2001 |
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
Topics: Acetylcysteine; Antioxidants; Calcium; Calcium Signaling; Carcinoma, Hepatocellular; Chelating Agents; DNA-Binding Proteins; Egtazic Acid; Gallic Acid; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Genes, Reporter; Hepacivirus; Humans; Liver Neoplasms; Luciferases; Neoplasm Proteins; NF-kappa B; Oxidative Stress; Pyrrolidines; Reactive Oxygen Species; Recombinant Fusion Proteins; STAT3 Transcription Factor; Thiocarbamates; Trans-Activators; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Nonstructural Proteins | 2001 |
Activation of NF-kB mediates ICAM-1 induction in respiratory cells exposed to an adenovirus-derived vector.
Topics: Acetylcysteine; Adenoviridae; Antioxidants; Cell Line; Chloramphenicol O-Acetyltransferase; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Intercellular Adhesion Molecule-1; Lung; NF-kappa B; Peptides; Pyrrolidines; RNA, Messenger; Sesquiterpenes; Thiocarbamates; Translocation, Genetic | 2001 |
Reactive oxygen intermediates induce monocyte chemotactic protein-1 in vascular endothelium after brief ischemia.
Topics: Acetylcysteine; Animals; Cells, Cultured; Chemokine CCL2; Dogs; Endothelium, Vascular; Free Radical Scavengers; Hydrogen Peroxide; Ischemia; Myocardium; NF-kappa B; Oxidants; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Tissue Distribution; Transcription Factor AP-1; Venules | 2001 |
Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress.
Topics: Acetylcysteine; Antioxidants; DNA-Binding Proteins; Hepatitis B virus; Humans; Mitochondria; NF-kappa B; Oxidative Stress; Phosphorylation; Pyrrolidines; STAT3 Transcription Factor; Superoxide Dismutase; Thiocarbamates; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Viral Regulatory and Accessory Proteins | 2001 |
Induction of MMP-9 in normal human bronchial epithelial cells by TNF-alpha via NF-kappa B-mediated pathway.
Topics: Acetylcysteine; Antioxidants; Bronchi; Cells, Cultured; Free Radical Scavengers; Humans; Interleukin-1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Pneumonia; Pyrrolidines; Respiratory Mucosa; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2001 |
Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Chorion; DNA Fragmentation; Female; Gene Expression; Humans; In Vitro Techniques; Labor, Obstetric; Masoprocol; Oxidative Stress; Pregnancy; Pyrrolidines; RNA, Messenger; Superoxide Dismutase; Thiocarbamates; Trophoblasts | 2001 |
Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Blotting, Western; Cell Nucleus; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Endotoxins; Heart; Lipopolysaccharides; Mice; Multienzyme Complexes; Myocardium; NF-kappa B; Proteasome Endopeptidase Complex; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Thiocarbamates; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2002 |
N-acetyl-L-cysteine suppresses constitutive expression of CD11a/LFA-1alpha protein in myeloid lineage.
Topics: Acetylcysteine; Antioxidants; Cell Lineage; DNA Probes; Down-Regulation; HL-60 Cells; Humans; Lymphocyte Function-Associated Antigen-1; Monocytes; Myeloid Cells; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Protein Binding; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; U937 Cells | 2002 |
Pyrrolidine dithiocarbamate induces cyclooxygenase-2 expression in NIH 3T3 fibroblast cells.
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Chelating Agents; Copper; Cyclooxygenase 2; Dinoprostone; Dithiothreitol; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Isoenzymes; Kinetics; Metals; Mice; Oxidants; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; RNA, Messenger; Thiocarbamates | 2002 |
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
Topics: Acetylcysteine; Aldehydes; alpha 1-Antitrypsin; Antioxidants; Chlorine; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrocyanides; Glutathione; Hypochlorous Acid; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Serum Albumin; Thiocarbamates | 2002 |
NF-kappa B is required for surface Ig-induced Fas resistance in B cells.
Topics: Acetylcysteine; Animals; Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocyte Subsets; bcl-X Protein; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cells, Cultured; fas Receptor; Gene Products, tat; HIV; I-kappa B Proteins; Immunoglobulin M; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; tat Gene Products, Human Immunodeficiency Virus; Thiocarbamates | 2003 |
Zinc toxicity on neonatal cortical neurons: involvement of glutathione chelation.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Cell Death; Cells, Cultured; Chelating Agents; Coculture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Maleates; Neuroglia; Neurons; Pyrrolidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thiocarbamates; Zinc | 2003 |
Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumour cells.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Base Sequence; Benzoquinones; Brain Neoplasms; Carrier Proteins; Endoplasmic Reticulum; Heat-Shock Proteins; Kinetics; Lactams, Macrocyclic; Molecular Chaperones; Molecular Sequence Data; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Quinones; Rats; Reactive Oxygen Species; Response Elements; RNA, Messenger; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured | 2003 |
Evidence that reactive oxygen species do not mediate NF-kappaB activation.
Topics: Acetylcysteine; Base Sequence; Cell Line; DNA Primers; Humans; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 2003 |
Phosphoinositide 3-kinase activity leads to silica-induced NF-kappaB activation through interacting with tyrosine-phosphorylated I(kappa)B-alpha and contributing to tyrosine phosphorylation of p65 NF-kappaB.
Topics: Acetylcysteine; Androstadienes; Animals; Antioxidants; Blotting, Western; Cell Line; Cell Nucleus; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Lipopolysaccharides; Mice; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Pyrrolidines; Reactive Oxygen Species; Silicon Dioxide; Superoxide Dismutase; Thiocarbamates; Time Factors; Tyrosine; Wortmannin | 2003 |
Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kappa B activity in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Brain Ischemia; Hippocampus; I-kappa B Proteins; Male; Neurons; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiocarbamates; Transcription Factor RelA | 2003 |
Blocking NF-kappaB activation may be an effective strategy in the fever therapy.
Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antibodies, Monoclonal; Curcumin; Cytokines; Fever; Humans; Injections, Intravenous; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Male; NF-kappa B; Pyridines; Pyrrolidines; Rabbits; Thiocarbamates; Thiones; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
NF-kappaB activation: is it really redox regulated?
Topics: Acetylcysteine; Animals; Antioxidants; Dimerization; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Thiocarbamates | 2003 |
Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Humans; Hydrogen Peroxide; Inflammation; Interleukin-1; Mice; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteins; Myelin Proteolipid Protein; Myelin Sheath; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Oligodendroglia; Oxidants; Oxidation-Reduction; Phosphoric Diester Hydrolases; Proline; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Oxidative stress and apoptotic changes in murine splenocytes exposed to cadmium.
Topics: Acetylcysteine; Animals; Apoptosis; Cadmium; Caspase 3; Caspases; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Combinations; Environmental Pollutants; G1 Phase; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondrial Membranes; Necrosis; Oxidative Stress; Pyrrolidines; Spleen; Thiocarbamates | 2006 |
N-Acetyl-L-cysteine and pyrrolidine dithiocarbamate inhibited nuclear factor-kappaB activation in alveolar macrophages by different mechanisms.
Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Macrophages, Alveolar; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Pulmonary Disease, Chronic Obstructive; Pyrrolidines; Thiocarbamates; Tumor Necrosis Factor-alpha | 2006 |
Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA Primers; Fibroblasts; Flavonoids; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoblotting; Mice; Oligonucleotides, Antisense; Pancreatic Neoplasms; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; Thiocarbamates | 2006 |
Elevated reactive oxygen species but not glutathione regulate mercury resistance to AML-2/DX100 cells.
Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Imidazoles; Mercuric Chloride; Multidrug Resistance-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Probenecid; Pyridines; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates | 2006 |
Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells.
Topics: Acetylcysteine; Analysis of Variance; Antioxidants; Apoptosis; Caspase 3; Cells, Cultured; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Luminescent Measurements; Pyrrolidines; Radiation, Ionizing; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates; Thromboplastin; Tumor Necrosis Factor-alpha; Umbilical Veins | 2007 |
Involvement of reactive oxygen species in aclarubicin-induced death of human trisomic and diabetic fibroblasts.
Topics: Acetylcysteine; Aclarubicin; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Calcium; Cell Line; Diabetes Mellitus, Type 2; Down Syndrome; Fibroblasts; Humans; Membrane Potential, Mitochondrial; Necrosis; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates | 2007 |
Upregulation of cyclooxygenase-2 by motorcycle exhaust particulate-induced reactive oxygen species enhances rat vascular smooth muscle cell proliferation.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Proliferation; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Motorcycles; Muscle, Smooth, Vascular; NF-kappa B; Prostaglandins E, Synthetic; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Thiocarbamates; Up-Regulation; Vehicle Emissions | 2007 |
N-acetylcysteine inhibits induction of nitric oxide synthase in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Induction; Interleukin-6; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pyrrolidines; Stimulation, Chemical; Thiocarbamates; Tumor Necrosis Factor-alpha | 2007 |
The potency of anti-oxidants in attenuating superantigen-induced proinflammatory cytokines correlates with inactivation of NF-kappaB.
Topics: Acetylcysteine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antioxidants; Cells, Cultured; Cytokines; Enterotoxins; Glutathione; Humans; Interleukin-2 Receptor alpha Subunit; Lectins, C-Type; Lymphocyte Activation; Monocytes; NF-kappa B; Pyrrolidines; Superantigens; T-Lymphocytes; Thiocarbamates | 2008 |
Type I collagen induces tissue factor expression and matrix metalloproteinase 9 production in human primary monocytes through a redox-sensitive pathway.
Topics: Acetophenones; Acetylcysteine; Base Sequence; Blotting, Western; Cells, Cultured; Collagen Type I; Cytokines; DNA Primers; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Oxidation-Reduction; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates; Thromboplastin | 2008 |
Involvement of Bcl-2 family in apoptosis and signal pathways induced by cigarette smoke extract in the human airway smooth muscle cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Cycle; Cell Survival; Cells, Cultured; Fas Ligand Protein; fas Receptor; Gene Expression; Humans; Lung; Myocytes, Smooth Muscle; NF-kappa B p50 Subunit; Nicotiana; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Smoke; Thiocarbamates; Transcription Factor RelA | 2009 |
Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells.
Topics: Acetylcysteine; Animals; Cells, Cultured; Curcumin; Cyclooxygenase 2; Free Radical Scavengers; Gene Expression Regulation; Isoquinolines; Leupeptins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Piperidines; Poly Adenosine Diphosphate Ribose; Pyrrolidines; Rabbits; Stress, Mechanical; Structure-Activity Relationship; Synovial Membrane; Thiocarbamates | 2010 |
Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB.
Topics: Acetylcysteine; Animals; Antioxidants; Down-Regulation; Gene Expression Regulation; Glucuronidase; Humans; Indican; Klotho Proteins; NF-kappa B; Pyrrolidines; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sesquiterpenes; Thiocarbamates | 2011 |
Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Antiviral Agents; Chlorocebus aethiops; Chromans; Coronavirus Infections; Cytopathogenic Effect, Viral; DNA Fragmentation; Flow Cytometry; Porcine epidemic diarrhea virus; Pyrrolidines; Quercetin; Reactive Oxygen Species; Thiocarbamates; Vero Cells; Virus Replication | 2011 |
DEDC, a new flavonoid induces apoptosis via a ROS-dependent mechanism in human neuroblastoma SH-SY5Y cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclohexanones; Flavones; Humans; Neuroblastoma; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Thiocarbamates; Tumor Suppressor Protein p53 | 2012 |
[Hypoxia upregulates the expression of annexin A1 in lung adenocarcinoma a549 cells].
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Adenocarcinoma; Annexin A1; Antioxidants; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Thiocarbamates; Up-Regulation | 2012 |
Regulation of ROS in transmissible gastroenteritis virus-activated apoptotic signaling.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Free Radical Scavengers; Gastroenteritis, Transmissible, of Swine; Membrane Potential, Mitochondrial; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Swine; Thiocarbamates; Transmissible gastroenteritis virus; Tumor Suppressor Protein p53 | 2013 |
Nonylphenol regulates cyclooxygenase-2 expression via Ros-activated NF-κB pathway in sertoli TM4 cells.
Topics: Acetylcysteine; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Interleukin-6; Male; Mice; NF-kappa B; Phenols; Pyrrolidines; Reactive Oxygen Species; Sertoli Cells; Signal Transduction; Thiocarbamates; Up-Regulation | 2015 |
β-Hydroxybutyrate activates the NF-κB signaling pathway to promote the expression of pro-inflammatory factors in calf hepatocytes.
Topics: 3-Hydroxybutyric Acid; Acetylcysteine; Animals; Cattle; Cells, Cultured; Glutathione Peroxidase; Hepatocytes; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1beta; Interleukin-6; Malondialdehyde; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Pyrrolidines; Signal Transduction; Superoxide Dismutase; Thiocarbamates; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Suppression of prolactin signaling by pyrrolidine dithiocarbamate is alleviated by N-acetylcysteine in mammary epithelial cells.
Topics: Acetylcysteine; Animals; Caseins; Cattle; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Insulin; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Mammary Glands, Animal; Mice; NF-kappa B; Phosphorylation; Pregnancy; Prolactin; Pyrrolidines; Serine; Signal Transduction; Thiocarbamates | 2014 |
The pyridone-annelated isoindigo (5'-Cl) induces apoptosis, dysregulation of mitochondria and formation of ROS in leukemic HL-60 cells.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line, Tumor; Cytochromes c; HL-60 Cells; Humans; Indoles; Leukemia, Promyelocytic, Acute; Membrane Potential, Mitochondrial; Mitochondria; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridones; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates | 2015 |
Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury.
Topics: Acetylcysteine; Animals; Cell Line, Transformed; Chemokine CCL2; Gene Expression Regulation; Glucose; Inflammation; Mice; NF-kappa B; Podocytes; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Toll-Like Receptor 4 | 2015 |
Antioxidant therapy improves non-thyroidal illness syndrome in uremic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Euthyroid Sick Syndromes; Female; Free Radical Scavengers; Male; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Thiocarbamates; Uremia | 2016 |
The roles of NF-κB and ROS in regulation of pro-inflammatory mediators of inflammation induction in LPS-stimulated zebrafish embryos.
Topics: Acetylcysteine; Animals; Embryo, Nonmammalian; Fish Diseases; Fish Proteins; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Zebrafish | 2017 |
Zn-doped CuO nanocomposites inhibit tumor growth by NF-κB pathway cross-linked autophagy and apoptosis.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Copper; Humans; Mice; Mice, Nude; Nanocomposites; NF-kappa B; Pyrrolidines; Reactive Oxygen Species; Signal Transduction; Thiocarbamates; Zinc | 2019 |
Prolonged PM2.5 exposure elevates risk of oxidative stress-driven nonalcoholic fatty liver disease by triggering increase of dyslipidemia.
Topics: Acetylcysteine; Air Pollutants; Animals; Dyslipidemias; Hepatocytes; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Metabolic Syndrome; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Particulate Matter; Pyrrolidines; Signal Transduction; Thiocarbamates | 2019 |
Porcine epidemic diarrhea virus infections induce apoptosis in Vero cells via a reactive oxygen species (ROS)/p53, but not p38 MAPK and SAPK/JNK signalling pathways.
Topics: Acetylcysteine; Animals; Apoptosis; Benzothiazoles; Chlorocebus aethiops; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Porcine epidemic diarrhea virus; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Toluene; Tumor Suppressor Protein p53; Vero Cells | 2019 |
NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells.
Topics: Acetylcysteine; Apoptosis; Calcium-Binding Proteins; Cataract; Cells, Cultured; Epithelial Cells; Humans; Lens, Crystalline; p38 Mitogen-Activated Protein Kinases; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Transcription Factor RelA; Ultraviolet Rays | 2020 |