Compounds > pyrrolidine
Page last updated: 2024-08-23

pyrrolidine and pyrroles

pyrrolidine has been researched along with pyrroles in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199013 (43.33)18.7374
1990's0 (0.00)18.2507
2000's7 (23.33)29.6817
2010's9 (30.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Fotsch, C; St Jean, DJ1
Hackling, AE; Stark, H1
Dooley, DM; Lee, Y; Ling, KQ; Lu, X; Sayre, LM; Shepard, EM; Silverman, RB1
Gwoździński, K; Jóźwiak, Z; Kania, K; Koceva-Chyła, A; Sokal, A1
Gwoździński, K; Jóźwiak, Z; Koceva-Chyła, A; Kochman, A; Stolarska, A1
MANN, PJ; SMITHIES, WR1
BALL, CD; BYERRUM, RU; DEWEY, LJ1
CLARKE, AJ; MANN, PJ1
BYERRUM, RU; GRIFFITH, T; WU, PH1
HASSE, K; SCHMID, G1
CAVALLA, JF; SCOTTI, L; SELWAY, RA; WAX, J; WINDER, CV1
INUBUSHI, Y; KONITA, T; MATSUMOTO, S; TSUDA, Y1
HONEGGER, CG; LANGEMANN, HM1
CAVALLA, JF; JONES, R; WAX, J; WELFORD, M; WINDER, CV1
BOWMAN, ER; MCKENNIS, H; SCHWARTZ, SL1
GOODMAN, L; GUEFFROY, DE; REIST, EJ1
BISHOP, DC; CAVALLA, JF; SELWAY, RA; WEBB, NE1
DeKam, RN; Fleck, TJ; McWhorter, WW; Pearlman, BA1
Coffin, AR; Pelkey, ET; Roussell, MA; Tserlin, E1
Garrison, SL; Gonzalez, C; Marquez, M; Thweatt, WD; Zhao, YL1
LOCKETT, MF1
Gualandi, A; Journot, G; Letondor, C; Neier, R; Savoia, D; Stoeckli-Evans, H1
Burgess, K; Ioerger, TR; Ko, E; Perez, LM; Raghuraman, A1
Bagryanskaya, EG; Gatilov, YV; Grigor'ev, IA; Kirilyuk, IA; Krumkacheva, OA; Polienko, YF; Strizhakov, RK1
Bagryanskaya, EG; Fedin, MV; Jicsinszky, L; Krumkacheva, OA; Marque, SR; Polovyanenko, DN1
Cardona, F; Giusti, L; Goti, A; Parmeggiani, C; Reissig, HU1
Ichii, Y; Ito, Y; Kakiuchi, M; Miyata, O; Shono, H; Ueda, M1
Garner, P; Hu, J; Van Houten, I; Weerasinghe, L1
Berg, K; Paletta, JT; Rajca, A; Rajca, S; Reinhart, E; Wang, Y1
Dong, S; Fan, H; Hu, W; Ji, J; Reddy, AGK; Sajjad, F; Xing, D; You, Q1

Reviews

2 review(s) available for pyrrolidine and pyrroles

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012
Dopamine D3 receptor ligands with antagonist properties.
    Chembiochem : a European journal of chemical biology, 2002, Oct-04, Volume: 3, Issue:10

    Topics: Amides; Animals; Benzazepines; Dopamine D2 Receptor Antagonists; Drug Design; Indans; Isoquinolines; Ligands; Piperazines; Pyrroles; Pyrrolidines; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Substrate Specificity; Tetrahydronaphthalenes

2002

Other Studies

28 other study(ies) available for pyrrolidine and pyrroles

ArticleYear
3-pyrrolines are mechanism-based inactivators of the quinone-dependent amine oxidases but only substrates of the flavin-dependent amine oxidases.
    Journal of the American Chemical Society, 2002, Oct-16, Volume: 124, Issue:41

    Topics: Amine Oxidase (Copper-Containing); Animals; Cattle; Enzyme Activation; Enzyme Inhibitors; Kinetics; Mitochondria, Liver; Monoamine Oxidase; Pyrroles; Pyrrolidines; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity

2002
The nitroxides pirolin and pirolid protect the plasma membranes of rat cardiomyocytes against damage induced by anthracyclines.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:1

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Cell Membrane; Cyclic N-Oxides; Doxorubicin; Fluorescence Polarization; Fluorescent Dyes; In Vitro Techniques; Male; Membrane Fluidity; Myocytes, Cardiac; Nitrogen Oxides; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Stearic Acids

2003
Effects of pyrroline and pyrrolidine nitroxides on lipid peroxidation in heart tissue of rats treated with doxorubicin.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Heart; Lipid Peroxidation; Malondialdehyde; Myocardium; Nitrogen Oxides; Pyrroles; Pyrrolidines; Rats; Rats, Wistar

2003
Plant enzyme reactions leading to the formation of heterocyclic compounds. 1. The formation of unsaturated pyrrolidine and piperidine compounds.
    The Biochemical journal, 1955, Volume: 61, Issue:1

    Topics: Oxidoreductases; Piperidines; Plants; Pyrroles; Pyrrolidines

1955
The biosynthesis of the pyrrolidine ring of nicotine.
    Biochimica et biophysica acta, 1955, Volume: 18, Issue:1

    Topics: Biochemical Phenomena; Nicotine; Prostheses and Implants; Pyrroles; Pyrrolidines

1955
Plant enzyme reactions leading to the formation of heterocyclic compounds. 3. Plant amine oxidase and the formation of pyrrolidine and piperidine alkaloids.
    The Biochemical journal, 1959, Volume: 71, Issue:4

    Topics: Alkaloids; Amines; Oxidoreductases; Piperidines; Pyrroles; Pyrrolidines

1959
Synthesis of pyrrolidine ring of nicotine from several C14-labeled metabolites by Nicotiana rustica.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Nicotiana; Nicotine; Prostheses and Implants; Pyrroles; Pyrrolidines

1962
[ENZYMATIC SYNTHESES OF PYRROLIDINE- AND PIPERIDINE ALKALOIDS].
    Biochemische Zeitschrift, 1963, Jul-26, Volume: 337

    Topics: Alkaloids; Amines; Piperidines; Pyrroles; Pyrrolidines

1963
ANALGETICS BASED ON THE PYRROLIDINE RING. II.
    Journal of medicinal and pharmaceutical chemistry, 1962, Volume: 5

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chemical Phenomena; Chemistry; Pharmacology; Pyrroles; Pyrrolidines; Rats; Research; Toxicology

1962
SHIHUNINE: A NEW PHTHALIDE-PYRROLIDINE ALKALOID.
    Chemical & pharmaceutical bulletin, 1964, Volume: 12

    Topics: Alkaloids; Benzofurans; Chemistry, Pharmaceutical; Lactones; Phthalic Acids; Pyrroles; Pyrrolidines; Research

1964
DETERMINATION OF PYRROLIDINE AND PIPERIDINE.
    Analytical biochemistry, 1964, Volume: 8

    Topics: Chromatography; Piperidines; Pyrroles; Pyrrolidines; Research; Spectrophotometry

1964
ANALGETICS BASED ON THE PYRROLIDINE RING. 3.
    Journal of medicinal chemistry, 1964, Volume: 7

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chemistry, Pharmaceutical; Pharmacology; Pyrroles; Pyrrolidines; Rats; Research; Toxicology

1964
ALTERNATE ROUTES IN THE METABOLIC DEGRADATION OF THE PYRROLIDINE RING OF NICOTINE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Animals; Butyrates; Chromatography; Dogs; Metabolism; Nicotine; Pyrroles; Pyrrolidines; Rats; Research; Spectrophotometry

1964
SYNTHESIS OF 4-ACETAMIDO-1,2,3,5-TETRA-O-ACETYL-4-DEOXY-D-RIBOFURANOSE. A PYRROLIDINE SUGAR.
    Journal of the American Chemical Society, 1965, Feb-05, Volume: 87

    Topics: Amino Sugars; Animals; Characidae; Chemical Phenomena; Chemistry; Pyrroles; Pyrrolidines; Research

1965
ANALGETICS BASED ON THE PYRROLIDINE RING. IV.
    Journal of medicinal chemistry, 1965, Volume: 8

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chemistry, Pharmaceutical; Pharmacology; Pyrroles; Pyrrolidines; Rats; Research; Toxicology

1965
Synthesis of N-methyl-N-[(1S)-1-[(3R)-pyrrolidin-3-yl]ethyl]amine.
    The Journal of organic chemistry, 2003, Dec-12, Volume: 68, Issue:25

    Topics: Alkylation; Amines; Anti-Bacterial Agents; Fluoroquinolones; Pyrroles; Pyrrolidines; Quinolones; Stereoisomerism; Structure-Activity Relationship

2003
Regiocontrolled synthesis of pyrrole-2-carboxaldehydes and 3-pyrrolin-2-ones from pyrrole Weinreb amides.
    The Journal of organic chemistry, 2006, Aug-18, Volume: 71, Issue:17

    Topics: Amides; Cyanides; Molecular Structure; Pyrroles; Pyrrolidines; Stereoisomerism

2006
N-nitrosation of amines by NO2 and NO: a theoretical study.
    The journal of physical chemistry. A, 2007, Mar-22, Volume: 111, Issue:11

    Topics: Amines; Entropy; Heterocyclic Compounds; Hydrogen Bonding; Models, Chemical; Models, Molecular; Molecular Conformation; Nitric Oxide; Nitrogen Dioxide; Nitrosation; Nitroso Compounds; Pyrroles; Pyrrolidines

2007
Some pharmacological actions of piperidine, pyrrolidine, and of pressor concentrates from dog urine.
    British journal of pharmacology and chemotherapy, 1949, Volume: 4, Issue:2

    Topics: Animals; Dogs; Piperidines; Pyrroles; Pyrrolidines; Quinidine

1949
Catalytic hydrogenation of meso-octamethylporphyrinogen (calix[4]pyrrole).
    Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Apr-12, Volume: 16, Issue:14

    Topics: Calixarenes; Catalysis; Hydrogenation; Models, Molecular; Molecular Structure; Porphyrins; Pyrroles; Pyrrolidines; Solubility; Solvents; Stereoisomerism

2010
Pyrrolinone-pyrrolidine oligomers as universal peptidomimetics.
    Journal of the American Chemical Society, 2011, Aug-17, Volume: 133, Issue:32

    Topics: Models, Molecular; Peptidomimetics; Protein Structure, Secondary; Pyrroles; Pyrrolidines

2011
Synthesis of 2,5-bis(spirocyclohexane)-substituted nitroxides of pyrroline and pyrrolidine series, including thiol-specific spin label: an analogue of MTSSL with long relaxation time.
    The Journal of organic chemistry, 2012, Sep-21, Volume: 77, Issue:18

    Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mesylates; Molecular Structure; Nitric Oxide; Pyrroles; Pyrrolidines; Spin Labels; Spiro Compounds; Sulfhydryl Compounds

2012
Structural equilibrium in new nitroxide-capped cyclodextrins: CW and pulse EPR study.
    The journal of physical chemistry. B, 2013, Jul-11, Volume: 117, Issue:27

    Topics: Cyclodextrins; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Kinetics; Nitrogen Oxides; Piperidines; Pyrroles; Pyrrolidines; Spin Labels

2013
Stereocomplementary routes to hydroxylated nitrogen heterocycles: total syntheses of casuarine, australine, and 7-epi-australine.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Aug-05, Volume: 19, Issue:32

    Topics: Alkadienes; Alkaloids; Heterocyclic Compounds; Nitrogen; Oxidation-Reduction; Pyrroles; Pyrrolidines; Pyrrolizidine Alkaloids; Stereoisomerism

2013
Direct synthesis of benzofuro[2,3-b]pyrroles through a radical addition/[3,3]-sigmatropic rearrangement/cyclization/lactamization cascade.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, May-26, Volume: 20, Issue:22

    Topics: Benzofurans; Cyclization; Free Radicals; Oximes; Pyrroles; Pyrrolidines; Stereoisomerism

2014
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin.
    Chemical communications (Cambridge, England), 2014, May-18, Volume: 50, Issue:38

    Topics: Carbon; Catalysis; Eupenicillium; Nitrogen; Pyrroles; Pyrrolidines; Receptors, Ionotropic Glutamate; Stereoisomerism

2014
Synthesis of unnatural amino acids functionalized with sterically shielded pyrroline nitroxides.
    Organic letters, 2014, Oct-17, Volume: 16, Issue:20

    Topics: Amino Acids; Ascorbic Acid; Cyclic N-Oxides; Cysteine; Glutathione; Molecular Structure; Oxidation-Reduction; Pyrroles; Pyrrolidines; Stereoisomerism

2014
Synthesis and biological evaluation of substituted pyrrolidines and pyrroles as potential anticancer agents.
    Archiv der Pharmazie, 2020, Volume: 353, Issue:12

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HCT116 Cells; HeLa Cells; HL-60 Cells; Humans; Inhibitory Concentration 50; Jurkat Cells; Molecular Structure; Neoplasms; PC-3 Cells; Pyrroles; Pyrrolidines; Structure-Activity Relationship; Time Factors

2020