Compounds > pyrrolidine
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pyrrolidine and pyrimidinones

pyrrolidine has been researched along with pyrimidinones in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paul, K; Singh, P1
Juarez-Brambila, JJ; Kamath, VP; Morris, PE1
Kokotos, CG; Kokotos, G; Limnios, D; Trifonidou, M; Triggidou, D1
Bagrodia, S; Cheng, H; Dalvie, D; Greasley, S; Huang, X; Knighton, DR; LaFleur Rogers, CM; Le, PT; Ninkovic, S; Pannifer, A; Plewe, M; Sun, S; Wang, H; Zhang, E1

Other Studies

4 other study(ies) available for pyrrolidine and pyrimidinones

ArticleYear
Anti-cancer activities of 5-acyl-6-[2-hydroxy/benzyloxy-3-(amino)-propylamino]-1,3-dialkyl-1H-pyrimidin-2,4-diones.
    Bioorganic & medicinal chemistry, 2006, Dec-15, Volume: 14, Issue:24

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Piperidines; Propanolamines; Pyrimidines; Pyrimidinones; Pyrrolidines; Structure-Activity Relationship

2006
Synthesis of labeled BCX-4208, a potent inhibitor of purine nucleoside phosphorylase.
    Drug testing and analysis, 2009, Volume: 1, Issue:3

    Topics: Catalysis; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Inhibitors; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrrolidines; Static Electricity; Tandem Mass Spectrometry

2009
Novel pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as highly effective catalysts for the asymmetric Michael addition.
    Organic & biomolecular chemistry, 2011, May-07, Volume: 9, Issue:9

    Topics: Catalysis; Molecular Structure; Pyrimidinones; Pyrrolidines; Stereoisomerism; Sulfhydryl Compounds; Thiohydantoins

2011
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Drug Design; Half-Life; Humans; Mice; Microsomes, Liver; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridones; Pyrimidines; Pyrimidinones; Pyrrolidines; Rats; Structure-Activity Relationship; TOR Serine-Threonine Kinases

2012