pyrrolidine-2,4-dicarboxylic acid has been researched along with dizocilpine maleate in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (31.25) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massieu, L; Morales-Villagrán, A; Tapia, R | 1 |
| Dutertre, M; Forni, C; Kerkerian-Le Goff, L; Liévens, JC; Salin, P | 1 |
| Cebere, A; Cebers, G; Liljequist, S; Wägner, A | 1 |
| Brown, DR | 1 |
| Cebers, G; Kovács, AD; Liljequist, S | 1 |
| Carter, AG; Regehr, WG | 1 |
| Bauer, J; Blauth, E; Darstein, M; Feuerstein, TJ; Freiman, TM; Hummel, A; Jehle, T | 1 |
| Gómez-Román, N; Massieu, L; Montiel, T | 1 |
| Kuo, JS; Lin, NN; Tsai, PJ; Yang, CS | 1 |
| Himi, T; Ikeda, M; Murota, SI; Yasuhara, T | 1 |
| Cebere, A; Cebers, G; Kovács, AD; Liljequist, S | 1 |
| Haces, ML; Hernández-Fonseca, K; Massieu, L; Montiel, T | 1 |
| Helliwell, P; Maleszka, R; Si, A | 1 |
| Auberson, YP; Bashir, ZI; Brown, MW; Collingridge, GL; Johnson, BE; Massey, PV; Molnar, E; Moult, PR | 1 |
| Tapia, R; Tovar-y-Romo, LB | 1 |
| Bendotti, C; Rattray, M | 1 |
16 other study(ies) available for pyrrolidine-2,4-dicarboxylic acid and dizocilpine maleate
| Article | Year |
|---|---|
Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study.
Topics: Animals; Cell Death; Choline; Choline O-Acetyltransferase; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Extracellular Space; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Kainic Acid; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar | 1995 |
Continuous administration of the glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate produces striatal lesion.
Topics: Animals; Biological Transport; Corpus Striatum; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Situ Hybridization; Infusion Pumps, Implantable; Molecular Weight; Nerve Degeneration; Neurotransmitter Uptake Inhibitors; Osmotic Pressure; Pyrrolidines; Rats; Rats, Wistar | 1997 |
Prolonged inhibition of glutamate reuptake down-regulates NMDA receptor functions in cultured cerebellar granule cells.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Cytoplasm; Dicarboxylic Acids; Dizocilpine Maleate; DNA Fragmentation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Glutamates; Histones; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1999 |
Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity.
Topics: Animals; Astrocytes; Cell Communication; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Memantine; Mice; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Signal Transduction; Tritium | 1999 |
Prolonged enhancement of AP-1 DNA binding by blockade of glutamate uptake in cultured neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Biological Transport; Cells, Cultured; Cerebellum; Dicarboxylic Acids; Dimerization; Dizocilpine Maleate; DNA-Binding Proteins; Excitatory Amino Acid Antagonists; Glutamic Acid; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Transcription Factor AP-1 | 1999 |
Prolonged synaptic currents and glutamate spillover at the parallel fiber to stellate cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebellum; Dicarboxylic Acids; Dizocilpine Maleate; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Nerve Fibers; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 2000 |
Effects of riluzole on electrically evoked neurotransmitter release.
Topics: Acetylcholine; Animals; Calcium; Dicarboxylic Acids; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Mice; Neostriatum; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Riluzole; Serotonin; Tetrodotoxin; Tritium | 2000 |
In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate.
Topics: Animals; Dicarboxylic Acids; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycolysis; Hippocampus; Iodoacetates; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 2000 |
Diethylmaleate decreased ascorbic acid release induced by cerebral ischemia in cerebral cortex of the anesthetized rat.
Topics: Amino Acid Transport System X-AG; Anesthesia; Animals; Ascorbic Acid; Brain Chemistry; Brain Ischemia; Carrier Proteins; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Infarction, Middle Cerebral Artery; Male; Maleates; Microdialysis; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Symporters | 2000 |
Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons.
Topics: Acetylcysteine; Amino Acid Transport System X-AG; Animals; Antioxidants; Aspartic Acid; Cell Death; Cells, Cultured; Dicarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Glutathione; Hippocampus; Neurons; Neurotransmitter Uptake Inhibitors; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Reactive Oxygen Species | 2003 |
Loss of GABAergic neuronal phenotype in primary cerebellar cultures following blockade of glutamate reuptake.
Topics: Animals; Animals, Newborn; Carrier Proteins; Cell Death; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Indicators and Reagents; Membrane Proteins; Membrane Transport Proteins; Neurofilament Proteins; Neurons; Neurotransmitter Uptake Inhibitors; Organic Anion Transporters; Organic Chemicals; Propidium; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2003 |
Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition.
Topics: Acetoacetates; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dicarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycolysis; Hippocampus; Iodoacetates; Male; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Pregnancy; Pyrrolidines; Pyruvic Acid; Quinoxalines; Rats; Rats, Wistar; Time Factors | 2003 |
Effects of NMDA receptor antagonists on olfactory learning and memory in the honeybee (Apis mellifera).
Topics: Animals; Bees; Cyclohexenes; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Learning; Limonene; Memantine; Memory; Mental Recall; Neural Pathways; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Smell; Terpenes | 2004 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.
Topics: 4-Aminopyridine; Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Dicarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; HSP72 Heat-Shock Proteins; Humans; Mice; Mice, Transgenic; Microdialysis; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Superoxide Dismutase | 2006 |
Does excitotoxic cell death of motor neurons in ALS arise from glutamate transporter and glutamate receptor abnormalities?
Topics: Amyotrophic Lateral Sclerosis; Animals; Biological Transport; Cell Death; Dicarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Mice; Motor Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Receptors, Glutamate | 2006 |