pyrrolidine-2,4-dicarboxylic acid has been researched along with aspartic acid in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (37.21) | 18.2507 |
| 2000's | 23 (53.49) | 29.6817 |
| 2010's | 4 (9.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balcar, VJ; Killinger, S; Li, Y | 1 |
| Balcar, VJ; Bao, S; King, NJ; Shen, J | 1 |
| Balcar, VJ; Li, Y | 1 |
| Hansen, L; Suzdak, PD; Thomsen, C | 1 |
| Johnston, GA; Mitrovic, AD | 1 |
| Andersson, K; Chen, Y; Espinoza, S; Godukhin, OV; Goiny, M; Herrera-Marschitz, M; Loidl, CF; Lubec, G; Meana, JJ; Nylander, I; Pettersson, E; Silveira, R; Terenius, L; Ungerstedt, U; You, ZB | 1 |
| Massieu, L; Tapia, R; Velasco, I | 1 |
| Ghijsen, WE; Lopes da Silva, FH; Veenstra, E; Zuiderwijk, M | 1 |
| Allan, RD; Balcar, VJ; Bested, A; Blume, GL; Bohart, L; Cooper, B; Dias, LS; Killinger, S | 1 |
| Boutelle, M; Demestre, M; Fillenz, M | 1 |
| Cano, J; Machado, A; Matarredona, ER; Santiago, M | 1 |
| Barbour, B; Clark, BA | 1 |
| Massieu, L; Tapia, R | 1 |
| Kennedy, RT; Lada, MW; Vickroy, TW | 1 |
| Massieu, L; Sánchez-Carbente, MR | 1 |
| Billups, D; Kinney, GA; Liu, YB; Overstreet, LS; Slater, NT | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Araque, A; Doyle, RT; Haydon, PG; Li, N | 1 |
| Isaac, JT; Kidd, FL | 1 |
| Balcar, VJ; Chebib, M; Cooper, B; Dias, LS; Lieb, I | 1 |
| Boussin, FD; Dereuddre-Bosquet, N; Dormont, D; Gras, G; Haïk, S; Le Grand, R; Martin, M; Rimaniol, AC | 1 |
| Gähwiler, BH; Gerber, U; Jabaudon, D; Scanziani, M | 1 |
| Cameron, RS; Conway, SJ; Fei, YJ; Friedrich, A; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wang, J | 1 |
| Balcar, VJ; Bubb, WA; Dias, LS; Lawrance, ML; Provis, T; Rae, C | 1 |
| Bézine, MF; Gaillet, S; Malaval, F; Plachez, C; Récasens, M | 1 |
| Abe, K; Saito, H | 1 |
| Chatton, JY; Magistretti, PJ; Shimamoto, K | 1 |
| Falzano, L; Fiorentini, C; Frank, C; Giammarioli, AM; Rufini, S | 1 |
| Bert, L; Denoroy, L; Desvignes, C; Parrot, S; Renaud, B; Robert, F; Suaud-Chagny, MF | 1 |
| Himi, T; Ikeda, M; Murota, SI; Yasuhara, T | 1 |
| Lariosa-Willingham, KD; Rao, TS; Yu, N | 1 |
| Auberson, YP; Bashir, ZI; Brown, MW; Collingridge, GL; Johnson, BE; Massey, PV; Molnar, E; Moult, PR | 1 |
| Gebhardt, C; Heinemann, U; Iserhot, C; Schmitz, D | 1 |
| Camacho, A; Estrada-Sánchez, AM; Massieu, L; Montiel, T | 1 |
| Qu, H; Schousboe, A; Shimamoto, K; Sonnewald, U; Waagepetersen, HS | 1 |
| Cohen-Solal, C; de Jesus Ferreira, MC; Guiramand, J; Martin, A; Récasens, M; Vignes, M | 1 |
| Jones, IW; Pullar, IA; Rousseau, SJ; Wonnacott, S | 1 |
| Juneja, LR; Okubo, T; Terashima, T; Yamada, T; Yokogoshi, H | 1 |
| Had-Aissouni, L; Kachidian, P; Kerkerian-Le Goff, L; Masmejean, F; Melon, C; Nafia, I; Nieoullon, A; Re, DB | 1 |
| Kardos, J; Lasztóczi, B; Nyitrai, G | 1 |
| Crespo-López, ME; do Nascimento, JL; Garcia, TB; Herculano, AM; Mota, TC; Oliveira, KR; Picanço-Diniz, DL | 1 |
| del Rio, RM; Feldmann, N; Gjinovci, A; Tamarit-Rodriguez, J; Wiederkehr, A; Wollheim, CB | 1 |
| Chae, JW; Choi, JI; Heo, BH; Kim, HS; Kim, WM; Lee, HG; Park, KS; Yoon, MH | 1 |
43 other study(ies) available for pyrrolidine-2,4-dicarboxylic acid and aspartic acid
| Article | Year |
|---|---|
Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino-4-propyl-5-phosphono-3-pentenoate (CGP 39653), [3H]6-cya
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Kainic Acid; Neurotransmitter Uptake Inhibitors; Prosencephalon; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 1995 |
Na(+)-dependent high affinity uptake of L-glutamate in primary cultures of human fibroblasts isolated from three different types of tissue.
Topics: Aspartic Acid; Biological Transport; Cells, Cultured; Dicarboxylic Acids; Fibroblasts; Glutamates; Glutamic Acid; Humans; Kinetics; Muscles; Peripheral Nerves; Pyrrolidines; Skin; Sodium; Tritium | 1994 |
The Na(+)-dependent binding of [3H]L-aspartate in thaw-mounted sections of rat forebrain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Autoradiography; Dicarboxylic Acids; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Neurotransmitter Uptake Inhibitors; Presynaptic Terminals; Prosencephalon; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Sodium | 1994 |
L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
Topics: Alanine Transaminase; Animals; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Cricetinae; Cycloleucine; Cysteine; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Glutamic Acid; Hydrolysis; Kidney; N-Methylaspartate; Phosphatidylinositols; Pyrrolidines; Receptors, Metabotropic Glutamate | 1994 |
Regional differences in the inhibition of L-glutamate and L-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes by L-trans-pyrrolidine-2,4-dicarboxylate, threo-3-hydroxy-D-aspartate and D-aspartate.
Topics: Analysis of Variance; Animals; Aspartic Acid; Biological Transport; Cerebellum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Male; Organ Specificity; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium; Spinal Cord; Stereoisomerism | 1994 |
On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis.
Topics: Amino Acids; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Basal Ganglia; Calcium; Cerebral Cortex; Dicarboxylic Acids; Glutamic Acid; Halothane; Kainic Acid; Male; Membrane Potentials; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Potassium; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spider Venoms; Substantia Nigra; Tetrodotoxin; Urethane | 1996 |
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo release of amino acids in rat hippocampus.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dicarboxylic Acids; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Potassium; Pyrrolidines; Rats; Rats, Wistar; Taurine | 1996 |
Autoradiographic studies indicate regional variations in the characteristics of L-glutamate transporters in the rat brain.
Topics: Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Binding Sites; Biological Transport; Brain Chemistry; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Male; Neostriatum; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carrier Proteins; Corpus Striatum; Dicarboxylic Acids; Extracellular Space; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Grooming; Hippocampus; Lactic Acid; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Symporters | 1997 |
Lack of involvement of glutamate-induced excitotoxicity in MPP+ toxicity in striatal dopaminergic terminals: possible involvement of ascorbate.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acids, Essential; Animals; Ascorbic Acid; Aspartic Acid; Dicarboxylic Acids; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Immunohistochemistry; Male; Microdialysis; MPTP Poisoning; Neostriatum; Nerve Endings; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 1997 |
Currents evoked in Bergmann glial cells by parallel fibre stimulation in rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cadmium; Cerebellum; Dicarboxylic Acids; Electric Stimulation; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Male; Nerve Fibers; Neuroglia; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Synapses; Tetrodotoxin | 1997 |
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 1997 |
Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex.
Topics: Animals; Aspartic Acid; Benzoates; Calcium; Corpus Striatum; Cycloleucine; Dicarboxylic Acids; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Male; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin; Time Factors | 1998 |
Transient inhibition of glutamate uptake in vivo induces neurodegeneration when energy metabolism is impaired.
Topics: Animals; Antihypertensive Agents; Aspartic Acid; Biological Transport; Brain Chemistry; Corpus Striatum; Dicarboxylic Acids; Energy Metabolism; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neurotoxins; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Propionates; Pyrrolidines; Rats; Rats, Wistar | 1999 |
Glutamate transporters contribute to the time course of synaptic transmission in cerebellar granule cells.
Topics: Aging; Animals; Aspartic Acid; Benzothiadiazines; Cerebellum; Dicarboxylic Acids; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Male; Neurons; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synaptic Transmission; Time Factors | 1999 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
SNARE protein-dependent glutamate release from astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Bacterial Agents; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Botulinum Toxins; Botulinum Toxins, Type A; Calcium; Cells, Cultured; Coculture Techniques; Dicarboxylic Acids; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Kainic Acid; Macrolides; Membrane Potentials; Membrane Proteins; Nerve Tissue Proteins; Neurons; Proton-Translocating ATPases; Pyrrolidines; Rats; SNARE Proteins; Vesicular Transport Proteins | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Quantitative autoradiography of Na+-dependent [3H]L-aspartate binding to L-glutamate transporters in rat brain: structure-activity studies using L-trans-pyrrolidine-2,4-dicarboxylate (L-t-PDC) and 2-(carboxycyclopropyl)-glycine (CCG).
Topics: Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Brain; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Female; Freezing; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium; Structure-Activity Relationship; Tritium | 2000 |
Na+-dependent high-affinity glutamate transport in macrophages.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Binding, Competitive; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Humans; Intracellular Fluid; Ion Transport; Macaca fascicularis; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Monocytes; Pyrrolidines; Sodium; Symporters; Tumor Necrosis Factor-alpha | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain.
Topics: Animals; Aspartic Acid; Astrocytes; Biological Transport; Brain; Carrier Proteins; Cell Line; Chlorides; Dicarboxylic Acid Transporters; Dicarboxylic Acids; Humans; Male; Pyrrolidines; Rats; Sodium | 2000 |
Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slices.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain; Cerebral Cortex; Dicarboxylic Acids; Female; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Oligodeoxyribonucleotides, Antisense; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thionucleotides | 2000 |
Transient increase in the high affinity [3H]-L-glutamate uptake activity during in vitro development of hippocampal neurons in culture.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Dicarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Kainic Acid; Neuroglia; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Symporters; Time Factors; Tritium | 2001 |
Possible linkage between glutamate transporter and mitogen-activated protein kinase cascade in cultured rat cortical astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurotransmitter Uptake Inhibitors; Phosphorylation; Pyrrolidines; Rats; Rats, Wistar; Receptors, Glutamate; Signal Transduction | 2001 |
Effects of glial glutamate transporter inhibitors on intracellular Na+ in mouse astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzofurans; Binding, Competitive; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Intracellular Fluid; Kainic Acid; Mice; Neurotransmitter Uptake Inhibitors; Protein Isoforms; Pyrrolidines; Sodium; Stereoisomerism | 2001 |
Glutamate-induced calcium increase in myotubes depends on up-regulation of a sodium-dependent transporter.
Topics: 2-Chloroadenosine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Calcium; Cell Differentiation; Cells, Cultured; Cycloheximide; Dicarboxylic Acids; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Protein Synthesis Inhibitors; Purines; Pyrrolidines; Symporters; Up-Regulation | 2002 |
In vivo temporal sequence of rat striatal glutamate, aspartate and dopamine efflux during apomorphine, nomifensine, NMDA and PDC in situ administration.
Topics: Animals; Apomorphine; Aspartic Acid; Dicarboxylic Acids; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Electrodes, Implanted; Electrophoresis, Capillary; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Microdialysis; N-Methylaspartate; Neostriatum; Neurotransmitter Uptake Inhibitors; Nomifensine; Online Systems; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2002 |
Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons.
Topics: Acetylcysteine; Amino Acid Transport System X-AG; Animals; Antioxidants; Aspartic Acid; Cell Death; Cells, Cultured; Dicarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Glutathione; Hippocampus; Neurons; Neurotransmitter Uptake Inhibitors; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Reactive Oxygen Species | 2003 |
Glutamate-dependent glutamine, aspartate and serine release from rat cortical glial cell cultures.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dexamethasone; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Glutamine; Neuroglia; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Serine; Time Factors | 2003 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cerebral Cortex; Dicarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Long-Term Potentiation; Long-Term Synaptic Depression; N-Methylaspartate; Neurons; Neurotransmitter Uptake Inhibitors; Phenols; Picrotoxin; Piperidines; Protein Subunits; Pyrrolidines; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 2004 |
Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Amino Acids; Animals; Aspartic Acid; Dicarboxylic Acids; Drug Interactions; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 2004 |
Differential effects of the substrate inhibitor l-trans-pyrrolidine-2,4-dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta-benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat
Topics: Animals; Aspartic Acid; Behavior, Animal; Cell Death; Corpus Striatum; Dicarboxylic Acids; Electroencephalography; Extracellular Space; Glutamic Acid; Hippocampus; Injections, Intraventricular; Male; Microdialysis; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 2005 |
Role of glutamine and neuronal glutamate uptake in glutamate homeostasis and synthesis during vesicular release in cultured glutamatergic neurons.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Brain; Cells, Cultured; Citric Acid Cycle; Dicarboxylic Acids; Excitatory Postsynaptic Potentials; Glutamic Acid; Glutaminase; Glutamine; Homeostasis; Mice; Mitochondria; Neurons; Potassium; Presynaptic Terminals; Pyrrolidines; Synaptic Transmission; Synaptic Vesicles | 2005 |
Gliotoxicity in hippocampal cultures is induced by transportable, but not by nontransportable, glutamate uptake inhibitors.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cell Death; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Neuroglia; Neurons; Neurotoxins; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2005 |
Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Aspartic Acid; Azetidines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Calcium; Choline; Cyanobacteria Toxins; Dicarboxylic Acids; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Frontal Lobe; Immunohistochemistry; In Vitro Techniques; Male; Marine Toxins; Mecamylamine; Microcystins; Microscopy, Confocal; Neurotransmitter Uptake Inhibitors; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphopyruvate Hydratase; Potassium Chloride; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Synaptosomes; Time Factors; Tritium; Tropanes | 2005 |
Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission.
Topics: Animals; Aspartic Acid; Brain; Dicarboxylic Acids; Dopamine; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 2005 |
Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Aspartic Acid; Cells, Cultured; Dicarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Mesencephalon; Neurons; Neurotransmitter Uptake Inhibitors; Phosphopyruvate Hydratase; Pregnancy; Pyrrolidines; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine 3-Monooxygenase | 2008 |
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Magnesium Deficiency; Male; Neurons; Neurotransmitter Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Glutamate induces glutathione efflux mediated by glutamate/aspartate transporter in retinal cell cultures.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cells, Cultured; Chick Embryo; Dicarboxylic Acids; Glutamic Acid; Glutathione; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Retina | 2011 |
Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells.
Topics: Alanine; Animals; Aspartic Acid; Cell Membrane; Cells, Cultured; Dicarboxylic Acids; Epinephrine; gamma-Aminobutyric Acid; Glucagon; Glucagon-Secreting Cells; Glucose; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ketoglutaric Acids; Malates; Male; Pyrrolidines; Rats; Rats, Wistar; Transcription, Genetic | 2011 |
The role of inversely operating glutamate transporter in the paradoxical analgesia produced by glutamate transporter inhibitors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amino Acid Transport System X-AG; Analgesics; Animals; Aspartic Acid; Dicarboxylic Acids; Extracellular Space; Formaldehyde; Glutamic Acid; Male; Nociception; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2016 |