pyrroles has been researched along with wortmannin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 13 (65.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anwer, MS; Webster, CR | 1 |
| Day, BN; Green, KM; Kim, JH; Prather, RS; Wang, WH | 1 |
| Bucana, CD; Ellis, LM; Gallick, GE; Jung, YD; McConkey, DJ; McMahon, G; Solorzano, CC | 1 |
| Huang, Y; Ishizawa, M; Ishizuka, T; Kajita, K; Kawai, Y; Kimura, M; Miura, A; Morita, H; Uno, Y; Yasuda, K | 1 |
| Arias, IM; Kagawa, T; Sai, Y; Varticovski, L | 1 |
| Ali, A; Huang, WC; Lin, WW; Wen, HC; Woodgett, JR | 1 |
| Blanquet, PR; Derer, P; Mariani, J | 1 |
| Francis, K; Ham, J; Lewis, BM; Lewis, MD; Rees, DA; Scanlon, MF | 1 |
| Deres, P; Halmosi, R; Hideg, K; Kalai, T; Kovacs, K; Sumegi, B; Toth, A; Toth, K | 1 |
| Beer, N; Dodt, J; Etscheid, M | 1 |
| Robinson, SA; Rosenzweig, SA | 1 |
| Baker, JE; Fu, X; Gross, GJ; Hsu, A; Strande, JL; Su, J | 1 |
| Seidler, U; Tuo, BG; Wen, GR | 1 |
| Hirata, H; Inagaki, H; Iwashita, K; Kamata, H; Kawauchi, K; Morikawa, T; Moriyama, Y; Shibukawa, Y; Tobiume, K | 1 |
| Bertone, C; Bianco, MJ; Brama, M; Castelli, A; Rossi, F; Santiemma, V | 1 |
| Chen, WJ; Hung, CR; Kuan, P; Shyu, KG; Wang, BW | 1 |
| Chaudagar, KK; Mehta, AA | 1 |
| Dong, X; Liu, L | 1 |
| Abe, A; Hayakawa, F; Ichihara, M; Inoue, C; Kawamoto, Y; Murate, T; Nishizawa, Y; Nozawa, Y; Sobue, S; Suzuki, M | 1 |
| Bahtiar, A; Fujio, Y; Kametani, Y; Kobayashi, A; Maeda, M; Matsumoto, K; Miyake, Y; Mori, S; Obana, M; Tanaka, S; Tomimatsu, M; Wahyuni, T; Yamamoto, A | 1 |
20 other study(ies) available for pyrroles and wortmannin
| Article | Year |
|---|---|
Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes.
Topics: Androstadienes; Animals; Apoptosis; Bile Acids and Salts; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indoles; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Solubility; Wortmannin | 1998 |
Effect of myosin light chain kinase, protein kinase A, and protein kinase C inhibition on porcine oocyte activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Carbazoles; Cell Nucleus; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Enzyme Inhibitors; Exocytosis; Female; Indoles; Microscopy, Electron; Myosin-Light-Chain Kinase; Oocytes; Protein Kinase C; Pyrroles; Swine; Wortmannin | 1999 |
In vivo intracellular signaling as a marker of antiangiogenic activity.
Topics: Androstadienes; Angiogenesis Inhibitors; Biomarkers, Tumor; Blotting, Western; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Humans; Indoles; Liver Neoplasms; Lymphokines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Oxindoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Propionates; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin | 2001 |
Differential effect of PKC isoform on insulin- and phorbol ester-stimulated glucose uptake mechanism in rat adipocytes.
Topics: Adipocytes; Androstadienes; Animals; Biological Transport, Active; Deoxyglucose; Enzyme Activation; Enzyme Inhibitors; Glucose; In Vitro Techniques; Indoles; Insulin; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.
Topics: Androstadienes; Animals; Bile Acids and Salts; Bile Canaliculi; Carbazoles; Cell Line; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; ras Proteins; Rats; Time Factors; Wortmannin | 2002 |
Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.
Topics: Androstadienes; Cell Line; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Maleimides; Mesylates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Serine; Signal Transduction; Wortmannin | 2003 |
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin | 2003 |
Adenosine-induced IL-6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Androstadienes; Animals; Cells, Cultured; Dexamethasone; Estrenes; Indoles; Interleukin-6; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pituitary Gland, Anterior; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, Adenosine A2B; Type C Phospholipases; Vascular Endothelial Growth Factors; Wortmannin | 2003 |
Akt activation induced by an antioxidant compound during ischemia-reperfusion.
Topics: Androstadienes; Animals; Antioxidants; Caspase 3; Caspases; Energy Metabolism; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydroxyl Radical; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mexiletine; Molecular Structure; Myocardial Contraction; Phosphatidylinositol 3-Kinases; Phosphocreatine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; Superoxides; Wortmannin | 2003 |
The hyaluronan-binding protease upregulates ERK1/2 and PI3K/Akt signalling pathways in fibroblasts and stimulates cell proliferation and migration.
Topics: Androstadienes; Butadienes; Cell Line; Cell Movement; Cell Proliferation; Culture Media, Conditioned; Fibroblasts; Humans; Lung; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrroles; Serine Endopeptidases; Skin; Time Factors; Up-Regulation; Wortmannin | 2005 |
Paradoxical effects of the phage display-derived peptide antagonist IGF-F1-1 on insulin-like growth factor-1 receptor signaling.
Topics: Androstadienes; Cell Cycle; Cell Line, Tumor; DNA Replication; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Peptide Library; Peptides, Cyclic; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction; Wortmannin | 2006 |
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
Topics: Androstadienes; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hirudins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; omega-N-Methylarginine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Recombinant Proteins; Research Design; RNA, Messenger; Signal Transduction; Thrombin; Time Factors; Ventricular Function, Left; Wortmannin | 2007 |
Phosphatidylinositol 3-kinase is involved in prostaglandin E2-mediated murine duodenal bicarbonate secretion.
Topics: Androstadienes; Animals; Bicarbonates; Calcium Signaling; Carbazoles; Chromones; Cyclic AMP; Dinoprostone; Duodenum; Flavonoids; Genistein; Imines; Indoles; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Sulfonamides; Verapamil; Wortmannin | 2007 |
Cycloprodigiosin hydrochloride activates the Ras-PI3K-Akt pathway and suppresses protein synthesis inhibition-induced apoptosis in PC12 cells.
Topics: Androstadienes; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cycloheximide; Cytoprotection; Dactinomycin; Indoles; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; ras Proteins; Rats; Signal Transduction; Wortmannin | 2008 |
Ghrelin induces proliferation in human aortic endothelial cells via ERK1/2 and PI3K/Akt activation.
Topics: Adenine; Androstadienes; Aorta; Carbazoles; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Flavonoids; Ghrelin; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Wortmannin | 2008 |
Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-beta1 in cultured cardiac fibroblasts.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Androstadienes; Animals; Antigens, CD; Apoptosis Regulatory Proteins; Atorvastatin; Cells, Cultured; Collagen Type I; Endoglin; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; MAP Kinase Signaling System; Myocardium; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Wortmannin | 2010 |
Effect of atorvastatin on the angiogenic responsiveness of coronary endothelial cells in normal and streptozotocin (STZ) induced diabetic rats.
Topics: Androstadienes; Animals; Anticholesteremic Agents; Atorvastatin; Benzophenanthridines; Chick Embryo; Chorioallantoic Membrane; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelial Cells; Enzyme Inhibitors; Heptanoic Acids; Male; Myocardial Reperfusion Injury; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A; Wortmannin | 2014 |
Complex impacts of PI3K/AKT inhibitors to androgen receptor gene expression in prostate cancer cells.
Topics: Androstadienes; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Molecular Targeted Therapy; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptors, Androgen; RNA Splicing; RNA Stability; Transcription Initiation, Genetic; Wortmannin | 2014 |
Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cyclin D2; Drug Resistance, Neoplasm; Drug Synergism; Glycogen Synthase Kinase 3; Humans; Imatinib Mesylate; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leupeptins; Macrocyclic Compounds; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 2; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Pyridazines; Pyrroles; Signal Transduction; Wortmannin | 2020 |
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Nuclear Receptor Subfamily 1, Group F, Member 1; Paracrine Communication; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Ribonucleosides; Signal Transduction; Sulfonamides; Thiophenes; Wortmannin | 2021 |