pyrroles has been researched along with triazoles in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (4.38) | 18.7374 |
| 1990's | 1 (0.73) | 18.2507 |
| 2000's | 26 (18.98) | 29.6817 |
| 2010's | 82 (59.85) | 24.3611 |
| 2020's | 22 (16.06) | 2.80 |
| Authors | Studies |
|---|---|
| Fotsch, C; St Jean, DJ | 1 |
| Berk, S; Gisser, H | 1 |
| Harris, PN; Lin, TM | 1 |
| Dunoff, RY; Graboyes, H; Jaffe, G; Karash, CB; Pachter, IJ; Snader, K; Weinstock, J | 1 |
| Van de Voorde, J; Vanheel, B | 1 |
| Kamal, A; Laxman, E; Laxman, N; Rao, NV | 1 |
| Dalvie, DK; Kalgutkar, AS; Khojasteh-Bakht, SC; O'Donnell, JP; Obach, RS | 1 |
| CaJacob, CA; Chott, RC; Collantes, EM; Hegde, SG; Loida, PJ; Mosier, PD; Profeta, S; Schweitzer, BA | 1 |
| Bigham, EC; Bishop, MJ; Garrison, DT; Hodson, SJ; Irving, PE; Liacos, JA; Navas, F; Saussy, DL; Sherman, BW; Speake, JD | 1 |
| BALLONOFF, LB; FEINSTEIN, RN; SEAHOLM, JE | 1 |
| BERNARD, Y; RINALDI, R | 1 |
| HAEGER-ARONSEN, B | 1 |
| Johnson, AA; Marchand, C; Pommier, Y | 1 |
| Diniz, C; Fresco, P; Gonçalves, J | 1 |
| Antilla, JC; Barder, TE; Baskin, JM; Buchwald, SL | 1 |
| Domenici, MR; Martire, A; Pepponi, R; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Basile, AS; Lippa, AS; Skolnick, P | 1 |
| Houshyar, H; Hsin, LW; Jutkiewicz, EM; Rice, KC; Wood, SK; Woods, JH | 1 |
| Devaiah, V; Kamal, A; Reddy, DR; Reddy, KL; Shankaraiah, N | 1 |
| Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ | 1 |
| Cheng, L; Xie, R; You, J; Zhang, Y; Zhu, L | 1 |
| Gomez, EV; Howey, DC; McErlean, E; Nicholls, SJ; Nissen, SE; Russo, JM; Wang, MD; Wolski, K | 1 |
| Kuehr, I; Núñez, O | 1 |
| Alves, CN; Andrés, J; Castillo, R; Martí, S; Moliner, V; Silla, E; Tuñón, I | 1 |
| Brooker, S; Hellyer, RM; Joule, JA; Larsen, DS | 1 |
| Barnett, CJ; Beck, JJ; Edwards, SG; Glynn, NC; Hare, MC; Parry, DW; Ray, R | 1 |
| Al-Mawsawi, LQ; Dayam, R; Neamati, N | 1 |
| Gadaginamath, GS; Joshi, SD; Vagdevi, HM; Vaidya, VP | 1 |
| Devaiah, V; Juvekar, A; Kamal, A; Kurian, N; Laxma Reddy, K; Sen, S; Shankaraiah, N; Zingde, S | 1 |
| Chen, JM; Chen, X; Hung, M; Jin, H; Jones, GS; Kim, CU; Qi, X; Swaminathan, S; Tsiang, M; Yu, F; Zeynalzadegan, A | 1 |
| Guo, J; Hu, Z; Wang, Q; Wu, J; Wu, X; Xu, J; Yin, Z | 1 |
| Barreca, ML; Chimirri, A; De Luca, L; Iraci, N | 1 |
| Ang, BW; Cheng, CL; Chou, N; Lee, KM; Lee, SC; Wong, AL | 1 |
| Cheng, Y; Ma, YG; Mo, JM | 1 |
| Fenoll, J; Flores, P; Hellín, P; Navarro, S; Ruiz, E | 1 |
| Akamatsu, Y; Takahashi, Y; Umezawa, Y; Watanabe, T | 1 |
| Jeong, KS; Juwarker, H | 1 |
| Arambula, JF; Cai, J; Gong, HY; Hay, BP; Sessler, JL; Yang, X | 1 |
| Bardas, GA; Doukas, EG; Kalampokis, JF; Karaoglanidis, GS; Konstantinou, S; Markoglou, AN | 1 |
| Hand, LH; Thomas, KA | 1 |
| Cristalli, G; Di Angelantonio, S; Grassi, F; Limatola, C; Moriconi, C; Piccioni, A; Trettel, F | 1 |
| Amijee, H; Kim, EM; Monaghan, J; O'Hare, E; Palmer, PM; Scopes, DI; Treherne, JM | 1 |
| Janaki Ramaiah, M; Kamal, A; Lakshmi Narayan Reddy, T; Mallareddy, A; Pal-Bhadra, M; Prabhakar, S; Pushpavalli, SN; Ratna Reddy, Ch; Shankaraiah, N; Venkat Reddy, P | 1 |
| Chattopadhyay, B; Gevorgyan, V | 1 |
| Cortopassi, WA; França, TC; Krettli, AU; Oliveira, AA; Penna-Coutinho, J | 1 |
| Bhome, R; Penn, H | 1 |
| Bi, YA; El-Kattan, AF; Fenner, KS; Iseki, K; Kimoto, E; Lai, Y; Linder, C; Walsky, R; Whalen, KM; Xiao, Y; Yang, YS; Zhang, H | 1 |
| Choi, YJ; Geaney, JC; Karpf, DB; Krauss, RM; Naim, S; Roberts, BK; Wang, X; Wojnoonski, K | 1 |
| Dürüst, Y; Kaiser, M; Karakuş, H; Tasdemir, D | 1 |
| Scheen, AJ | 1 |
| Kaczor, AA; Karczmarzyk, Z; Matosiuk, D; Pitucha, M; Rzymowska, J; Wysocki, W | 1 |
| Bhatt, L; Chang, CJ; Cotter, TG; Dickinson, BC; Gough, DR; Naughton, R; Stanicka, J; Woolley, JF | 1 |
| Bao, BY; Chang, CF; Chuang, TH; Laiu, MC; Mukkanti, K; Pusuluri, S; Sorra, K; Su, CH | 1 |
| Coppola, L; Karpouzas, DG; Marinozzi, M; Menkissoglu-Spiroudi, U; Monaci, E; Papadopoulou, E; Vischetti, C | 1 |
| Batalha, VL; Coelho, JE; Diógenes, MJ; Ferreira, DG; Gomes, R; Lopes, LV; Sebastião, AM; Valadas, JS | 1 |
| Budha, N; Hop, CE; Khojasteh, SC; Lyssikatos, J; Mulder, T; Rudewicz, PJ; Solon, E; Ware, JA; Wong, H; Yue, Q | 1 |
| Bolger, JK; Kirkland, LO; Kontopidis, G; Liu, S; McInnes, C; Perkins, TL; Premnath, PN | 1 |
| Chien, C; Colonno, RJ; D'Arienzo, C; Eggers, B; Gao, Q; Gong, YF; Grasela, DM; Kadow, JF; Langley, DR; Lin, PF; Malinowski, J; Mathew, M; Meanwell, NA; Parker, DD; Regueiro-Ren, A; Sun, Y; Swidorski, JJ; Wu, D; Xue, QM; Yang, Z; Zheng, M | 1 |
| Huang, XS; Jenkins, S; Johnson, KA; Kadow, JF; Meanwell, NA; Parker, D; Rahematpura, S; Regueiro-Ren, A; Simmermacher-Mayer, J; Sinz, M; Zheng, M | 1 |
| Aquilante, CL; Kosmiski, LA; Predhomme, JA; Sidhom, MS; Wempe, MF | 1 |
| Doukas, EG; Kalampokis, JF; Karaoglanidis, GS; Konstantinou, S; Malandrakis, AA; Markoglou, AN | 1 |
| Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z | 1 |
| Christensen, JG; Ishiguro-Oonuma, T; McDonald, DM; Schriver, BJ; Sennino, B | 1 |
| Biyajima, T; Hiraga, K; Miura, T; Murakami, M; Nakamuro, T | 1 |
| Alford, JS; Davies, HM; Spangler, JE | 1 |
| Hiraga, K; Miura, T; Murakami, M; Stewart, SG; Tanaka, T | 1 |
| Gevorgyan, V; Shi, Y | 1 |
| Chang, LS; Chen, CY; Chung, MI; Hsiao, CT; Hsu, CC; Hu, WP; Lee, PH; Lin, YT; Lin, YY; Wang, JJ; Yu, WT | 1 |
| Bi, QW; Chen, Z; Li, X; Li, XX; Shen, ZQ; Wang, Z; Wen, J; Zhu, LL | 1 |
| Yaqub, F | 1 |
| Eom, D; Kim, CE; Lee, PH; Park, S; Seo, B | 1 |
| Fraser, K | 1 |
| Castellano, R; Collette, Y; Crouzet, T; Gon, S; Goubard, A; Loosveld, M; Nadel, B; Payet-Bornet, D; Pouyet, L; Prebet, T; Vey, N | 1 |
| Gevorgyan, V; Gulevich, AV; Kuznetsov, A; Wink, DJ | 1 |
| He, J; Li, CY; Ran, RQ; Wang, KB; Xiu, SD | 1 |
| Anbarasan, P; Rajasekar, S | 1 |
| Matsumoto, K; Miura, T; Murakami, M; Tanaka, T | 1 |
| Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS | 1 |
| Shi, M; Tang, XY; Yang, HB; Zhao, YZ | 1 |
| Chen, BC; Lin, CH; Shih, CH | 1 |
| Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
| Gong, P; Luo, R; Tang, Q; Tu, Q; Tu, Y; Wang, L; Wang, P; Wu, C; Zheng, P; Zhu, W | 1 |
| Bernardelli, A; Bianchi, F; Braggio, S; Castelletti, L; Cavallini, P; Cavanni, P; Cremonesi, S; Dal Cin, M; Feriani, A; Heidbreder, C; Micheli, F; Oliosi, B; Semeraro, T; Tarsi, L; Tomelleri, S; Visentini, F; Wong, A; Zonzini, L | 1 |
| Gupte, A; Hawkins, CJ; Miles, MA; Shekhar, TM; Tascone, B; Taylor, S; Walkley, CR | 1 |
| Blobaum, AL; Cheung, YY; Conn, PJ; Daniels, JS; Gogliotti, RD; Hopkins, CR; Lindsley, CW; Loch, MT; Morrison, RM; Niswender, CM; Rodriguez, AL; Salovich, JM | 1 |
| Cho, WJ; Choi, S; Chung, YK; Han, SY; Kang, KW; Kim, J; Kim, YC; Ko, H; Lee, HJ; Lee, SM; Mukai, C; Yoon, KB | 1 |
| Iwata, S; Kubo, S; Nakayamada, S; Tanaka, Y | 1 |
| Bi, X; Sun, G; Zhang, L | 1 |
| Fan, X; Gong, P; Guo, Z; Li, Y; Liu, Y; Nie, M; Sun, X; Wang, Y; Yang, D; Zhang, F | 1 |
| Boudreau, TF; O'Keefe, SF; Peck, GM; Stewart, AC | 1 |
| Bonnemain, JL; Chollet, JF; Lei, ZW; Marhadour, S; Marivingt-Mounir, C; Wu, H; Yang, W | 1 |
| Ackermann, L; Cera, G; Haven, T | 1 |
| Birch, M; Buil, JB; Law, D; Meis, JF; Melchers, WJG; Rijs, AJMM; Verweij, PE | 1 |
| D'Haens, GR; De Vries, LCS; Hicks, KJ; Ludbrook, VJ | 1 |
| Boland, BS; Vermeire, S | 1 |
| Box, H; Colombo, AL; Hope, WW; Johnson, A; Kolamunnage-Dona, R; Livermore, J; McEntee, L; Negri, CE; Ramos-Martín, V; Schwartz, JA; Whalley, S | 1 |
| Bao, S; Lian, QQ; Liu, H; Lv, K; Su, Y; Wang, B; Wang, H; Wang, S; Zhou, WH | 1 |
| Chang, Q; Gu, S; Peng, Y; Sun, J; Wang, G; Wu, H; Zhang, X; Zhou, Y; Zhu, Y | 1 |
| Duan, Y; Li, X; Liu, X; Tang, Q; Wang, C; Wang, L; Xiao, Z; Zhao, B; Zheng, P; Zhu, W | 1 |
| Beneš, H; De Boer, P; Dorffner, G; Drevets, WC; Jahn, H; Keicher, C; Kent, JM; Kezic, I; Luthringer, R; Parapatics, S; Rofael, H; Seiden, DJ; van der Ark, P; van Gerven, J | 1 |
| Cocklin, S; Meuser, ME; Murphy, MB; Rashad, AA | 1 |
| de Boer, P; Golor, G; Nandy, P; van der Ark, PD; van Nueten, L | 1 |
| Chernysheva, NB; Demchuk, DV; Kiselyov, AS; Kislyi, VP; Konyushkin, LD; Maksimenko, AS; Raihstat, MM; Samet, AV; Semenov, VV; Semenova, MN; Silyanova, EA; Tsyganov, DV; Varakutin, AE | 1 |
| AnkiReddy, S; Bharathi Reddy, K; Rao Sagurthi, S; Sabitha, G; Shiva Raju, K; Siva Krishna, V; Sriram, D | 1 |
| Brooks, S; de Boer, P; Drevets, W; Jacobs, GE; Kent, JM; Kezic, I; Luthringer, R; van Amerongen, G; van der Ark, P; van Gerven, JM; Van Nueten, L; Zuiker, R | 1 |
| Liu, JY; Lo, PC; Ng, DKP; Shi, WJ | 1 |
| Westhovens, R | 1 |
| Dai, Y; Gao, T; Geng, J; Hu, J; Lamour, K; Liu, X; Ren, H; Zhou, Y | 1 |
| Bobde, Y; Ghosh, B; Nadh, RV; Sekhar, KVGC; Srinivasu, N; Thiriveedhi, A | 1 |
| Duan, W; Luo, C; Shao, J; Tao, H; Yan, X; Zhang, H; Zhu, K | 1 |
| Battat, R; Dulai, PS; Feagan, BG; Jairath, V; Ma, C; Parker, CE; Sandborn, WJ | 1 |
| Oliveira Udry, GA; Repetto, E; Varela, O | 1 |
| de Boer, P; Drevets, W; Jacobs, G; Kent, J; Luthringer, R; Recourt, K; van der Ark, P; van Gerven, J; Van Hove, I; van Nueten, L; Zuiker, R | 1 |
| Gatadi, S; Ghouse, SM; Godugu, C; Gour, J; Madhavi, YV; Malasala, S; Nanduri, S; Pooladanda, V | 1 |
| Lee, YH; Song, GG | 3 |
| Dowty, ME; Hegen, M; Jesson, MI; Katkade, V; Lin, TH; Martin, DA; Menon, S; Telliez, JB | 1 |
| Bonovas, S; Danese, S; Lasa, JS; Olivera, PA; Peyrin-Biroulet, L | 1 |
| Guo, D; Wang, D; Wang, Q; Wang, X; Wang, Y; Weng, H; Xu, C; Yang, G; Yu, R | 1 |
| Lefevre, PLC; Vande Casteele, N | 1 |
| Georgiou, S; Plachouri, KM | 1 |
| Adderley, T; Christopher, G; Irwin, MS; Kano, Y; Kee, L; Ladumor, Y; Ohh, M; Robinson, CM; Valencia-Sama, I | 1 |
| Bose, A; Pathak, T | 1 |
| Braeuning, A; Lasch, A; Lichtenstein, D; Marx-Stoelting, P | 1 |
| Chang, Y; Chen, J; Christiano, AM; Dai, Z | 1 |
| Avci, AB; Burmester, GR; Feist, E | 1 |
| Drevets, WC; Etropolski, M; Savitz, A; Thase, ME; Wajs, E; Xu, H; Zhang, Y | 1 |
| Bi, J; Liu, Q; Tan, Q; Wu, H; Zhang, G | 1 |
| Kim, JW; Kim, SY | 1 |
| Jeong, PH; Jung, JH; Kim, W; Kim, YC; Lee, SM | 1 |
| Jha, MK | 1 |
| Bonifaz, A; Burrows, J; Eadie, K; Fahal, A; Konings, M; Lim, W; Nyuykonge, B; Perry, B; Samby, K; Smeets, J; Todd, M; van de Sande, W; Verbon, A | 1 |
| Fujita, M; Haketa, Y; Maeda, H; Nishimura, T; Tanaka, H; Yasuda, N | 1 |
| Funt, LD; Khlebnikov, AF; Krivolapova, YV; Novikov, MS; Spiridonova, DV; Tomashenko, OA | 1 |
| He, X; Wang, H; Wu, M; Ye, Q; Zhou, T | 1 |
19 review(s) available for pyrroles and triazoles
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
Biotransformation reactions of five-membered aromatic heterocyclic rings.
Topics: Animals; Cytochrome P-450 Enzyme System; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Indoles; Isoxazoles; Models, Chemical; Molecular Structure; Oxadiazoles; Oxazoles; Pyrazoles; Pyrroles; Tetrazoles; Thiadiazoles; Thiazoles; Thiophenes; Triazoles; Xenobiotics | 2002 |
HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
Topics: Acetoacetates; Anti-HIV Agents; Biological Factors; Caffeic Acids; Clinical Trials as Topic; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Indoles; Models, Molecular; Molecular Structure; Oligonucleotides; Pyrroles; Reverse Transcriptase Inhibitors; Succinates; Tetrazoles; Triazoles | 2004 |
Anxioselective anxiolytics: can less be more?
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepinones; Carbolines; Clinical Trials as Topic; Fluorobenzenes; GABA-A Receptor Agonists; Humans; Indoles; Pyrroles; Quinolones; Triazoles | 2004 |
Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures.
Topics: Alkaloids; Benzodiazepines; Benzodiazepinones; Combinatorial Chemistry Techniques; Molecular Structure; Pyrroles; Triazoles | 2006 |
Anion-controlled foldamers.
Topics: Anions; Indoles; Polymers; Pyrroles; Triazoles; Urea | 2010 |
Pharmacokinetic evaluation of atorvastatin and sitagliptin in combination for the treatment of type 2 diabetes.
Topics: Atorvastatin; Blood Glucose; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrazines; Pyrroles; Risk Assessment; Sitagliptin Phosphate; Treatment Outcome; Triazoles | 2012 |
Recent Progress in JAK Inhibitors for the Treatment of Rheumatoid Arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinases; Molecular Targeted Therapy; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Triazoles | 2016 |
Janus Kinase Antagonists and Other Novel Small Molecules for the Treatment of Crohn's Disease.
Topics: B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Humans; Indans; Janus Kinase 1; Janus Kinase Inhibitors; Oligonucleotides; Oxadiazoles; Piperidines; Pyridines; Pyrimidines; Pyrroles; Receptors, Lysosphingolipid; Smad7 Protein; T-Lymphocytes; Triazoles | 2017 |
Clinical efficacy of new JAK inhibitors under development. Just more of the same?
Topics: Adamantane; Arthritis, Rheumatoid; Azetidines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinase 1; Janus Kinase 3; Janus Kinase Inhibitors; Niacinamide; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Treatment Outcome; Triazoles; Valine | 2019 |
Innovations in Oral Therapies for Inflammatory Bowel Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Discovery; Heterocyclic Compounds, 3-Ring; Humans; Indans; Inflammatory Bowel Diseases; Janus Kinase Inhibitors; Mesalamine; Oxadiazoles; Phosphodiesterase Inhibitors; Piperidines; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Receptors, Lysosphingolipid; Triazoles | 2019 |
Comparison of the efficacy and safety of tofacitinib and filgotinib in patients with active rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bayes Theorem; Drug Therapy, Combination; Humans; Methotrexate; Network Meta-Analysis; Piperidines; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2020 |
Safety of Janus Kinase Inhibitors in Patients With Inflammatory Bowel Diseases or Other Immune-mediated Diseases: A Systematic Review and Meta-Analysis.
Topics: Arthritis, Rheumatoid; Azetidines; Herpes Zoster; Heterocyclic Compounds, 3-Ring; Humans; Incidence; Inflammatory Bowel Diseases; Janus Kinase Inhibitors; Janus Kinases; Piperidines; Placebos; Psoriasis; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Spondylitis, Ankylosing; Sulfonamides; Survival Analysis; Treatment Outcome; Triazoles | 2020 |
Clinical Pharmacology of Janus Kinase Inhibitors in Inflammatory Bowel Disease.
Topics: Heterocyclic Compounds, 3-Ring; Humans; Inflammatory Bowel Diseases; Janus Kinase Inhibitors; Piperidines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2020 |
JAK inhibitors in chronic plaque psoriasis: What is known so far.
Topics: Adamantane; Azetidines; Humans; Janus Kinase Inhibitors; Janus Kinases; Niacinamide; Nitriles; Piperidines; Prospective Studies; Psoriasis; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Triazoles | 2020 |
Comparative efficacy and safety of tofacitinib, baricitinib, upadacitinib, and filgotinib in active rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Biological Products; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Treatment Outcome; Triazoles | 2021 |
Early phase studies of JAK1 selective inhibitors in rheumatoid arthritis.
Topics: Acetonitriles; Arthritis, Rheumatoid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |
The Era of Janus Kinase Inhibitors for Inflammatory Bowel Disease Treatment.
Topics: Adamantane; Colitis; Colitis, Ulcerative; Crohn Disease; Heterocyclic Compounds, 3-Ring; Humans; Inflammatory Bowel Diseases; Janus Kinase Inhibitors; Janus Kinases; Niacinamide; Piperidines; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
9 trial(s) available for pyrroles and triazoles
| Article | Year |
|---|---|
Effects of a potent and selective PPAR-alpha agonist in patients with atherogenic dyslipidemia or hypercholesterolemia: two randomized controlled trials.
Topics: Atorvastatin; Double-Blind Method; Dyslipidemias; Female; Fenofibrate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; PPAR alpha; Propionates; Pyrroles; Triazoles | 2007 |
Effects of the PPAR-δ agonist MBX-8025 on atherogenic dyslipidemia.
Topics: Acetates; Analysis of Variance; Atherosclerosis; Atorvastatin; Biomarkers; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Obesity; Overweight; Particle Size; PPAR gamma; Pyrroles; Time Factors; Treatment Outcome; Triazoles | 2012 |
Effect of ABCB1 polymorphisms and atorvastatin on sitagliptin pharmacokinetics in healthy volunteers.
Topics: Adult; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Cohort Studies; Colorado; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Genetic Association Studies; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Clearance Rate; Middle Aged; Polymorphism, Single Nucleotide; Pyrazines; Pyrroles; Sitagliptin Phosphate; Triazoles; Young Adult | 2013 |
A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Orexin Receptor Antagonists; Orexin Receptors; Polysomnography; Pyrimidines; Pyrroles; Sleep; Sleep Initiation and Maintenance Disorders; Sleepiness; Surveys and Questionnaires; Time Factors; Treatment Outcome; Triazoles; Young Adult | 2018 |
Multiple daytime administration of the selective orexin-2 receptor antagonist JNJ-42847922 induces somnolence in healthy subjects without residual central effects.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Male; Middle Aged; Orexin Receptor Antagonists; Orexin Receptors; Pyrimidines; Pyrroles; Sleepiness; Time Factors; Triazoles; Young Adult | 2018 |
The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia.
Topics: Adult; Aged; Antidepressive Agents; Cross-Over Studies; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Orexin Receptor Antagonists; Polysomnography; Pyrimidines; Pyrroles; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Triazoles; Young Adult | 2019 |
The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.
Topics: Adult; Antidepressive Agents; Arousal; Depressive Disorder, Major; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrimidines; Pyrroles; Sleep; Treatment Outcome; Triazoles | 2019 |
Efficacy and Safety of Seltorexant as Adjunctive Therapy in Major Depressive Disorder: A Phase 2b, Randomized, Placebo-Controlled, Adaptive Dose-Finding Study.
Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pyrimidines; Pyrroles; Treatment Outcome; Triazoles | 2021 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide | 2023 |
110 other study(ies) available for pyrroles and triazoles
| Article | Year |
|---|---|
Radiation chemistry of nitrogen and sulfur heterocyclics.
Topics: Chromatography, Gas; Free Radicals; Heterocyclic Compounds; Imidazoles; Nitrogen; Pyrazines; Pyrazoles; Pyrimidines; Pyrroles; Radiochemistry; Sulfur; Tetrazoles; Thiazoles; Thiophenes; Triazines; Triazoles | 1973 |
Experimental production of gastric and duodenal lesions by administration of 3-beta-aminoethyl 1,2,4-triazole.
Topics: Administration, Oral; Amines; Animals; Duodenal Ulcer; Duodenum; Fasting; Gastric Mucosa; Guinea Pigs; Injections, Intravenous; Male; Peptic Ulcer; Pylorus; Pyrroles; Rats; Stomach; Triazoles | 1970 |
Pteridines. 8. Some 2,4,7-triamino-6-heteroarylpteridines.
Topics: Chromatography, Paper; Furans; Hydrogen-Ion Concentration; Imidazoles; Oxazoles; Pteridines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Spectrum Analysis; Thiazoles; Thiophenes; Triazoles; Ultraviolet Rays | 1968 |
Influence of cytochrome P-450 inhibitors on endothelium-dependent nitro-L-arginine-resistant relaxation and cromakalim-induced relaxation in rat mesenteric arteries.
Topics: Acetylcholine; Animals; Benzopyrans; Biological Factors; Cromakalim; Cytochrome P-450 Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; In Vitro Techniques; Mesenteric Arteries; Miconazole; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Proadifen; Pyrroles; Rats; Rats, Wistar; Triazoles; Vasodilator Agents | 1997 |
Synthesis of pyrrolo[2,1-c[1,4]benzodiazepines via reductive cyclization of omega-azido carbonyl compounds by TMSI: an efficient preparation of antibiotic DC-81 and its dimers.
Topics: Anti-Bacterial Agents; Azepines; Benzodiazepines; Dimerization; Indicators and Reagents; Molecular Structure; Oxidation-Reduction; Pyrroles; Sodium Iodide; Structure-Activity Relationship; Triazoles; Trimethylsilyl Compounds | 2000 |
Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching.
Topics: Aldehydes; Binding Sites; Databases, Factual; Enzyme Inhibitors; Herbicides; Hydro-Lyases; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Pyrroles; Triazoles | 2002 |
2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: alpha1a subtype selective 2'-heteroaryl compounds.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Pyrazoles; Pyrroles; Structure-Activity Relationship; Triazoles | 2003 |
ATTEMPTS AT REDUCTION OF ERYTHROCYTE CATALASE LEVEL. II. ANL-6823.
Topics: Amides; Animals; Azoles; Benzoates; Catalase; Chloromercuribenzoates; Enzyme Inhibitors; Erythrocytes; Ferrocyanides; Glucose Oxidase; Indophenol; Iodoacetates; Ketones; Maleates; Mice; Naphthoquinones; Oxidation-Reduction; Pyrroles; Research; Streptomycin; Sulfhydryl Compounds; Sulfur; Triazoles | 1964 |
[RADIOPROTECTIVE ACTION OF NITROGENOUS HETEROCYCLIC COMPOUNDS].
Topics: Animals; Benzimidazoles; Heterocyclic Compounds; Imidazoles; Mice; Pharmacology; Piperazines; Purines; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyrimidines; Pyrroles; Radiation Injuries; Radiation Injuries, Experimental; Research; Triazoles | 1964 |
EXPERIMENTAL DISTURBANCE OF PORPHYRIN METABOLISM AND OF LIVER CATALASE ACTIVITY IN GUINEA PIGS AND RABBITS.
Topics: Amino Acids; Catalase; Enzyme Inhibitors; Feces; Griseofulvin; Guinea Pigs; Hexachlorocyclohexane; Lead Poisoning; Levulinic Acids; Liver; Porphyrias; Porphyrins; Pyrroles; Rabbits; Research; Toxicology; Triazoles; Urine | 1964 |
Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Arteries; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Indoles; Isoquinolines; Male; Norepinephrine; Phenethylamines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides; Tail; Tetradecanoylphorbol Acetate; Triazoles; Tritium; Type C Phospholipases | 2004 |
Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles.
Topics: Catalysis; Copper; Diamines; Imidazoles; Molecular Structure; Pyrazoles; Pyrroles; Triazoles | 2004 |
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Topics: Adenosine; Animals; Carbazoles; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Indoles; Male; Membrane Potentials; N-Methylaspartate; Phenethylamines; Phenylacetates; Pregnancy; Purinergic P1 Receptor Agonists; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Triazines; Triazoles | 2004 |
The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Swimming; Triazoles | 2005 |
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles | 2007 |
Highly efficient copper-catalyzed N-arylation of nitrogen-containing heterocycles with aryl and heteroaryl halides.
Topics: Catalysis; Copper; Hydrocarbons, Halogenated; Imidazoles; Iodides; Molecular Structure; Nitrogen; Pyrazoles; Pyrroles; Triazoles | 2007 |
Titanium dioxide photoinduced degradation of some pesticide/fungicide precursors.
Topics: Adsorption; Environmental Pollutants; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Pesticides; Pyrroles; Titanium; Triazoles; Ultraviolet Rays | 2007 |
Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Crystallography, X-Ray; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Lysine; Magnesium; Models, Chemical; Propane; Protein Conformation; Pyrroles; Structure-Activity Relationship; Triazoles | 2007 |
4-(Pyrrol-1-yl)-1,2,4-triazole.
Topics: Crystallography, X-Ray; Molecular Conformation; Pyrroles; Triazoles | 2007 |
Quantitative Fusarium spp. and Microdochium spp. PCR assays to evaluate seed treatments for the control of Fusarium seedling blight of wheat.
Topics: Antifungal Agents; Ascomycota; Benzimidazoles; Biphenyl Compounds; Crops, Agricultural; Dioxoles; DNA, Fungal; Fusarium; Mycoses; Plant Diseases; Polymerase Chain Reaction; Pyrroles; Seedlings; Seeds; Triazoles; Triticum | 2007 |
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
Topics: Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Molecular Structure; Organic Chemicals; Pyrroles; Pyrrolidinones; Quinolones; Raltegravir Potassium; Triazoles | 2007 |
Synthesis of new 4-pyrrol-1-yl benzoic acid hydrazide analogs and some derived oxadiazole, triazole and pyrrole ring systems: a novel class of potential antibacterial and antitubercular agents.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzoic Acid; Drug Design; Mycobacterium tuberculosis; Oxadiazoles; Pyrroles; Triazoles | 2008 |
Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; DNA; Humans; Kinetics; Neoplasms; Pyrroles; Triazoles | 2008 |
Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors.
Topics: Acetoacetates; Binding Sites; Crystallography, X-Ray; DNA, Viral; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Hydrophobic and Hydrophilic Interactions; Magnesium; Models, Chemical; Models, Molecular; Mutation; Naphthyridines; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrroles; Reproducibility of Results; Triazoles | 2008 |
Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Cattle; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Liver; Losartan; Male; Protein Binding; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Time Factors; Triazoles; Vasoconstriction | 2008 |
Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors.
Topics: Acetoacetates; Anti-HIV Agents; Binding Sites; Computer Simulation; Drug Design; Furans; HIV Integrase; HIV Integrase Inhibitors; Humans; Mutation; Naphthyridines; Pyrroles; Pyrrolidinones; Quinolones; Raltegravir Potassium; Triazoles | 2009 |
Subdural collections arising from calvarial metastases following discontinuation of anti-angiogenic therapy.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidine; Female; Fluorouracil; Goserelin; Hematoma, Subdural, Intracranial; Humans; Indoles; Letrozole; Leukopenia; Nitriles; Pyrroles; Skull; Sunitinib; Triazoles | 2009 |
Synthesis of novel synthetic intermediates from the reaction of benzimidazole and triazole carbenes with ketenimines and their application in the construction of spiro-pyrroles.
Topics: Benzimidazoles; Cyclization; Imines; Methane; Molecular Structure; Pyrroles; Spiro Compounds; Stereoisomerism; Triazoles | 2009 |
Solarization and biosolarization enhance fungicide dissipation in the soil.
Topics: Dioxoles; Environmental Restoration and Remediation; Fungicides, Industrial; Hot Temperature; Methacrylates; Phenylacetates; Photochemical Processes; Pyrimidines; Pyrroles; Soil; Soil Pollutants; Strobilurins; Triazoles | 2010 |
Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors.
Topics: Binding Sites; Computer Simulation; Enzyme Inhibitors; Humans; Intramolecular Transferases; Protein Structure, Tertiary; Pyrroles; Squalene; Structure-Activity Relationship; Triazoles | 2010 |
A pyrrolyl-based triazolophane: a macrocyclic receptor with CH and NH donor groups that exhibits a preference for pyrophosphate anions.
Topics: Anions; Diphosphates; Hydrogen Bonding; Pyrroles; Triazoles | 2010 |
Sensitivity of Penicillium expansum field isolates to tebuconazole, iprodione, fludioxonil and cyprodinil and characterization of fitness parameters and patulin production.
Topics: Aminoimidazole Carboxamide; Dioxoles; Fruit; Fungicides, Industrial; Greece; Hydantoins; Malus; Microbial Sensitivity Tests; Patulin; Penicillium; Pyrimidines; Pyrroles; Triazoles | 2011 |
Assessing the potential for algae and macrophytes to degrade crop protection products in aquatic ecosystems.
Topics: Benzamides; Biodegradation, Environmental; Chlorophyta; Dioxoles; Fresh Water; Heterocyclic Compounds, 2-Ring; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pesticides; Phenylurea Compounds; Photosynthesis; Plants; Prometryne; Pyrroles; Triazoles; Water Pollutants, Chemical | 2011 |
Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human (alpha)3(beta)4 nicotinic receptor.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine Deaminase; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiological Phenomena; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Receptor, Adenosine A2A; Receptors, Nicotinic; Signal Transduction; Superior Cervical Ganglion; Transfection; Triazoles | 2011 |
Novel anti-inflammatory compound SEN1176 alleviates behavioral deficits induced following bilateral intrahippocampal injection of aggregated amyloid-β₁₋₄₂.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Behavior, Animal; Behavioral Symptoms; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Hippocampus; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Time Factors; Triazoles | 2011 |
Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Chalcones; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; NF-kappa B; Pyrroles; Triazoles | 2011 |
Rh-catalyzed transannulation of N-tosyl-1,2,3-triazoles with terminal alkynes.
Topics: Alkynes; Catalysis; Combinatorial Chemistry Techniques; Molecular Structure; Pyrroles; Rhodium; Triazoles | 2011 |
Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.
Topics: Animals; Antimalarials; Atorvastatin; Catalytic Domain; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Itraconazole; L-Lactate Dehydrogenase; Malaria; Mice; Plasmodium falciparum; Pyrroles; Triazoles | 2011 |
Rhabdomyolysis precipitated by a sitagliptin-atorvastatin drug interaction.
Topics: Aged; Atorvastatin; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Male; Pyrazines; Pyrroles; Rhabdomyolysis; Sitagliptin Phosphate; Treatment Outcome; Triazoles | 2012 |
Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.
Topics: Anti-Anxiety Agents; Anticholesteremic Agents; Atorvastatin; Bile; Biological Transport; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorobenzenes; Hepatocytes; Heptanoic Acids; Humans; Isoenzymes; Midazolam; Models, Biological; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Time Factors; Triazoles | 2012 |
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles.
Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Oxadiazoles; Protozoan Infections; Pyrroles; Rats; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Triazoles | 2012 |
Structural and molecular docking studies of 4-benzyl-3-[(1-methylpyrrol- 2-yl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one with anticancer activity.
Topics: Antineoplastic Agents; Binding Sites; Cell Line; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Isomerism; Molecular Docking Simulation; Molecular Structure; Ovarian Neoplasms; Pyrroles; Triazoles | 2013 |
H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.
Topics: Benzoxazoles; Cell Line, Tumor; Endoplasmic Reticulum; Fluorescent Dyes; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hydrogen Peroxide; Imidazoles; Leukemia, Myeloid, Acute; Mitochondria; Mutation; NADPH Oxidases; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-pim-1; Pyrroles; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Triazoles | 2012 |
Synthesis and cytotoxicity testing of new amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Pyrroles; Sincalide; Triazoles | 2012 |
The dissipation of three fungicides in a biobed organic substrate and their impact on the structure and activity of the microbial community.
Topics: Analysis of Variance; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Dioxoles; Environmental Restoration and Remediation; Fungicides, Industrial; Gas Chromatography-Mass Spectrometry; Half-Life; Methacrylates; Microbial Consortia; Multivariate Analysis; Plant Components, Aerial; Principal Component Analysis; Pyrimidines; Pyrroles; Solid Phase Extraction; Strobilurins; Triazoles; Vitis | 2013 |
Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cerebral Cortex; Corticotropin-Releasing Hormone; Glutamic Acid; Neural Inhibition; Neurons; Neuroprotective Agents; Primary Cell Culture; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles | 2012 |
Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Autoradiography; Bile; Biotransformation; Carbon Radioisotopes; Cyclohexanes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Feces; Female; Half-Life; Hepatocytes; Hippurates; Hydrolysis; Injections, Intravenous; Isotope Labeling; Male; Mass Spectrometry; Metabolic Clearance Rate; Molecular Structure; Oxidation-Reduction; Pyrroles; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Tissue Distribution; Triazoles | 2013 |
Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly.
Topics: Adenosine Triphosphate; Cyclin-Dependent Kinases; Dipeptides; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Oligopeptides; Peptidomimetics; Pyrazoles; Pyrroles; Structure-Activity Relationship; Triazoles | 2013 |
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-p
Topics: Animals; Anti-HIV Agents; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; HIV-1; Humans; Indoles; Microsomes, Liver; Piperazines; Pyridines; Pyrroles; Quantum Theory; Rats; Structure-Activity Relationship; Triazines; Triazoles; Virus Attachment | 2013 |
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment 13. Synthesis and profiling of a novel amminium prodrug of the HIV-1 attachment inhibitor BMS-585248.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Dogs; Gastrointestinal Tract; High-Throughput Screening Assays; HIV-1; Humans; Liver; Male; Piperazines; Prodrugs; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Triazines; Triazoles; Virus Attachment | 2013 |
Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.
Topics: Aminoimidazole Carboxamide; Benzimidazoles; Carbamates; Dioxoles; Drug Resistance, Multiple, Fungal; Fruit; Fungicides, Industrial; Hydantoins; Malus; Mycotoxins; Patulin; Penicillium; Pyrazoles; Pyrimidines; Pyrroles; Strobilurins; Thiabendazole; Triazoles; Tubulin | 2013 |
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia.
Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones | 2013 |
Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic mice.
Topics: Animals; Antibodies; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Indoles; Lymphatic Metastasis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-met; Pyrazines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sunitinib; Triazoles; Vascular Endothelial Growth Factor C | 2013 |
Regiocontrolled synthesis of polysubstituted pyrroles starting from terminal alkynes, sulfonyl azides, and allenes.
Topics: Alkynes; Azides; Catalysis; Cyclization; Molecular Structure; Pyrroles; Stereoisomerism; Sulfones; Triazoles | 2013 |
Conversion of cyclic ketones to 2,3-fused pyrroles and substituted indoles.
Topics: Catalysis; Cyclization; Indoles; Ketones; Pyrroles; Rhodium; Triazoles | 2013 |
Stereoselective synthesis of 2,3-dihydropyrroles from terminal alkynes, azides, and α,β-unsaturated aldehydes via N-sulfonyl-1,2,3-triazoles.
Topics: Aldehydes; Alkynes; Azides; Catalysis; Molecular Structure; Pyrroles; Rhodium; Stereoisomerism; Sulfones; Triazoles | 2013 |
Intramolecular transannulation of alkynyl triazoles via alkyne-carbene metathesis step: access to fused pyrroles.
Topics: Alkynes; Cyclization; Methane; Molecular Structure; Organometallic Compounds; Pyrroles; Rhodium; Triazoles | 2013 |
Synthesis, DNA-binding abilities and anticancer activities of triazole-pyrrolo[2,1-c][1,4]benzodiazepines hybrid scaffolds.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Line, Tumor; Cyclin D1; DNA; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Humans; Isomerism; Mice; Pyrroles; Triazoles; Up-Regulation | 2013 |
Highly N2-selective coupling of 1,2,3-triazoles with indole and pyrrole.
Topics: Amino Acids; Catalysis; Halogenation; Indoles; Pyrroles; Stereoisomerism; Triazoles | 2014 |
American Society of Clinical Oncology Annual Meeting 2013.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Docetaxel; Erlotinib Hydrochloride; Female; Humans; Imidazoles; Indoles; Lung Neoplasms; Male; Medical Oncology; Multicenter Studies as Topic; Oximes; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Randomized Controlled Trials as Topic; Small Cell Lung Carcinoma; Societies, Medical; Sulfones; Sunitinib; Taxoids; Treatment Outcome; Triazoles; United States | 2013 |
Synthesis of pyrroles from terminal alkynes, N-sulfonyl azides, and alkenyl alkyl ethers through 1-sulfonyl-1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Ethers; Molecular Structure; Pyrroles; Sulfones; Triazoles | 2014 |
72nd annual meeting of the American Academy of Dermatology.
Topics: Antifungal Agents; Attention Deficit Disorder with Hyperactivity; Boron Compounds; Botulinum Toxins, Type A; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Depression; Dermatitis, Atopic; Food Hypersensitivity; Humans; Immunologic Factors; Ivermectin; Phosphodiesterase Inhibitors; Phototherapy; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinoxalines; Skin Diseases; Societies, Medical; Thalidomide; Triazoles; United States | 2014 |
Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azepines; Drug Screening Assays, Antitumor; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Mice; Nylons; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-myc; Pyrroles; Triazoles; Xenograft Model Antitumor Assays | 2014 |
A new reactivity mode for the diazo group: diastereoselective 1,3-aminoalkylation reaction of β-amino-α-diazoesters to give triazolines.
Topics: Alkylation; Amines; Mass Spectrometry; Pyrroles; Quinolones; Stereoisomerism; Triazoles | 2014 |
Synthesis of 3-pyrrolin-2-ones by rhodium-catalyzed transannulation of 1-sulfonyl-1,2,3-triazole with ketene silyl acetal.
Topics: Acetals; Catalysis; Ethylenes; Ketones; Pyrroles; Rhodium; Silanes; Sulfones; Triazoles | 2014 |
Rhodium-catalyzed transannulation of 1,2,3-triazoles to polysubstituted pyrroles.
Topics: Antineoplastic Agents; Catalysis; Molecular Structure; Pyrroles; Rhodium; Triazoles | 2014 |
One-pot synthesis of 2,5-dihydropyrroles from terminal alkynes, azides, and propargylic alcohols by relay actions of copper, rhodium, and gold.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Gold; Propanols; Pyrroles; Rhodium; Triazoles | 2014 |
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons.
Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones | 2015 |
Rh(II)-catalyzed [3+2] cycloaddition of 2 H-azirines with N-sulfonyl-1,2,3-triazoles.
Topics: Atorvastatin; Azirines; Benzyl Compounds; Catalysis; Cycloaddition Reaction; Pyrroles; Rhodium; Stereoisomerism; Triazoles | 2015 |
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells.
Topics: Animals; Apigenin; Casein Kinase II; Cells, Cultured; Epithelial Cells; Humans; Indoles; Interleukin-8; Lung; NF-kappa B; Phosphorylation; Pyrroles; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Thrombin; Transcription Factor RelA; Triazoles | 2015 |
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles | 2016 |
Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Pyrroles; Structure-Activity Relationship; Triazoles | 2016 |
1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Pyrroles; Receptors, Dopamine D3; Structure-Activity Relationship; Triazoles | 2016 |
IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Baculoviral IAP Repeat-Containing 3 Protein; Bone Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Cyclohexanes; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; HEK293 Cells; Humans; Inhibitor of Apoptosis Proteins; Mice, Knockout; Osteosarcoma; Phenotype; Pyrroles; Receptor-Interacting Protein Serine-Threonine Kinases; Retinoblastoma Protein; Signal Transduction; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Transfection; Triazoles; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases | 2016 |
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).
Topics: Allosteric Regulation; Animals; Microsomes, Liver; Picolinic Acids; Pyrroles; Rats; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Sulfonamides; Triazoles | 2016 |
The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Humans; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2016 |
Rhodium/Silver-Cocatalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Vinyl Azides: Divergent Synthesis of Pyrroles and 2 H-Pyrazines.
Topics: Azides; Catalysis; Cyclization; Pyrazines; Pyrroles; Rhodium; Silver; Triazoles | 2016 |
Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Factor Xa; Factor Xa Inhibitors; Humans; Models, Molecular; Molecular Structure; Pyrazoles; Pyridones; Pyrroles; Rabbits; Rats; Structure-Activity Relationship; Triazoles; Venous Thrombosis | 2016 |
The interactive effect of fungicide residues and yeast assimilable nitrogen on fermentation kinetics and hydrogen sulfide production during cider fermentation.
Topics: Alcoholic Beverages; Dietary Carbohydrates; Dioxoles; Fermentation; Food Contamination; Food Quality; Food, Preserved; Fruit and Vegetable Juices; Fungicides, Industrial; Hydrogen Sulfide; Kinetics; Malus; Nitriles; Nitrogen Cycle; Pesticide Residues; Pyrroles; Saccharomyces; Saccharomyces cerevisiae; Species Specificity; Sulfur; Triazoles; Virginia | 2017 |
Vectorization of agrochemicals: amino acid carriers are more efficient than sugar carriers to translocate phenylpyrrole conjugates in the Ricinus system.
Topics: Agrochemicals; Amino Acids; Biological Transport; Fungicides, Industrial; Glucose; Glutamic Acid; Phloem; Pyrroles; Ricinus; Sugars; Triazoles | 2018 |
Iron-Catalyzed C-H Alkynylation through Triazole Assistance: Expedient Access to Bioactive Heterocycles.
Topics: Alkynes; Catalysis; Iron; Phthalimides; Pyridones; Pyrroles; Quinolones; Triazoles | 2017 |
In vitro activity of the novel antifungal compound F901318 against difficult-to-treat Aspergillus isolates.
Topics: Acetamides; Antifungal Agents; Aspergillus; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Fungal Proteins; Genotype; Humans; Invasive Pulmonary Aspergillosis; Itraconazole; Microbial Sensitivity Tests; Nitriles; Piperazines; Point Mutation; Pyridines; Pyrimidines; Pyrroles; Triazoles; Voriconazole | 2017 |
GSK2586184, a JAK1 selective inhibitor, in two patients with ulcerative colitis.
Topics: Adult; Azetidines; C-Reactive Protein; Clinical Trials as Topic; Colitis, Ulcerative; Humans; Janus Kinase 1; Leukocyte L1 Antigen Complex; Male; Middle Aged; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Severity of Illness Index; Triazoles | 2017 |
Pharmacodynamics of the Novel Antifungal Agent F901318 for Acute Sinopulmonary Aspergillosis Caused by Aspergillus flavus.
Topics: Acetamides; Animals; Antifungal Agents; Aspergillus flavus; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Invasive Pulmonary Aspergillosis; Mice; Piperazines; Pyrimidines; Pyrroles; Triazoles; Voriconazole | 2018 |
Contribution of the α5 GABAA receptor to the discriminative stimulus effects of propofol in rat.
Topics: Animals; Carbolines; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluorobenzenes; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Imidazoles; Indoles; Male; Propofol; Pyridazines; Pyrroles; Random Allocation; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles | 2018 |
Atypical Kinetics and Albumin Effect of Glucuronidation of 5-n-Butyl-4-{4-[2-(1H-tetrazole-5- yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6- dichlorophenyl)-3H-1,2,4-triazol-3-one, a Novel Nonpeptide Angiotensin Type 1 Receptor Antagonist, in Liver
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Animals; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Metabolome; Microsomes, Liver; Middle Aged; Pyrroles; Receptor, Angiotensin, Type 1; Recombinant Proteins; Serum Albumin, Bovine; Triazoles | 2018 |
Discovery of novel pyrrolopyrimidine/pyrazolopyrimidine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.
Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; M Phase Cell Cycle Checkpoints; MCF-7 Cells; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Structure-Activity Relationship; Triazoles | 2018 |
Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency.
Topics: Anti-HIV Agents; Cell Line; Cell Survival; Drug Design; env Gene Products, Human Immunodeficiency Virus; HIV Envelope Protein gp120; HIV-1; Humans; Kinetics; Molecular Docking Simulation; Piperazines; Protein Binding; Protein Multimerization; Pyrroles; Structure-Activity Relationship; Surface Plasmon Resonance; Triazoles; Virus Internalization | 2018 |
Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
Topics: Animals; Antimitotic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Embryo, Nonmammalian; Humans; Isoxazoles; Pyrazoles; Pyrroles; Sea Urchins; Structure-Activity Relationship; Triazoles; Tubulin; Tubulin Modulators | 2018 |
Synthesis and biological evaluation of 1H-pyrrolo[2,3-d]pyrimidine-1,2,3-triazole derivatives as novel anti-tubercular agents.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrimidines; Pyrroles; Structure-Activity Relationship; Triazoles | 2019 |
Selective Detection of Hg
Topics: Boron Compounds; Fluorescence; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Limit of Detection; Mercury; Pyrroles; Rhodamines; Spectrometry, Fluorescence; Triazoles | 2019 |
Resistance risk assessment for fludioxonil in Sclerotinia homoeocarpa in China.
Topics: Aminoimidazole Carboxamide; Aminopyridines; Ascomycota; China; Dioxoles; Drug Resistance, Fungal; Fungal Proteins; Fungicides, Industrial; Gene Expression Regulation, Fungal; Hydantoins; Mutation; Pyrroles; Thiophanate; Triazoles | 2019 |
Design, synthesis and anti-tumour activity of new pyrimidine-pyrrole appended triazoles.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; ErbB Receptors; Humans; Mice; Molecular Docking Simulation; Pyrimidines; Pyrroles; Triazoles | 2019 |
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity.
Topics: Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Methylation; Molecular Docking Simulation; Neoplasms; Protein Binding; Protein-Arginine N-Methyltransferases; Pyrimidines; Pyrroles; Quinolines; Structure-Activity Relationship; Triazoles | 2019 |
Intramolecular azide-alkene cycloaddition-elimination reaction in an aldohex-2-enonic acid derivative.
Topics: Alkenes; Azides; Cycloaddition Reaction; Enzyme Inhibitors; Molecular Structure; Pyrroles; Triazoles | 2019 |
Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Binding Sites; Catalysis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Copper; Cycloaddition Reaction; DNA; Drug Screening Assays, Antitumor; Humans; Indoles; Membrane Potential, Mitochondrial; Molecular Conformation; Molecular Docking Simulation; Nucleic Acid Conformation; Pyrroles; Triazoles | 2019 |
Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Cell Line; Cytokines; Enzyme Assays; Female; Healthy Volunteers; Heterocyclic Compounds, 3-Ring; Humans; Inhibitory Concentration 50; Janus Kinase 1; Janus Kinase Inhibitors; Male; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Receptors, Cytokine; Sulfonamides; Triazoles | 2019 |
Combined toxic effects of fludioxonil and triadimefon on embryonic development of zebrafish (Danio rerio).
Topics: Animals; Dioxoles; Ecosystem; Embryo, Nonmammalian; Embryonic Development; Larva; Oxidative Stress; Pyrroles; Superoxide Dismutase; Triazoles; Water Pollutants, Chemical; Zebrafish | 2020 |
Relative efficacy and safety of tofacitinib, baricitinib, upadacitinib, and filgotinib in comparison to adalimumab in patients with active rheumatoid arthritis.
Topics: Adalimumab; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Bayes Theorem; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; Humans; Methotrexate; Piperidines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Sulfonamides; Treatment Outcome; Triazoles | 2020 |
Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Genes, ras; Heterografts; Humans; Indoles; Male; MAP Kinase Signaling System; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase Kinases; Mutation; Neoplasm Recurrence, Local; Neuroblastoma; Piperidines; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Triazoles; Vemurafenib | 2020 |
Vinyl sulfone-modified carbohydrates: Michael acceptors and 2π partners for the synthesis of functionalized sugars and enantiomerically pure carbocycles and heterocycles.
Topics: Acids, Carbocyclic; Amino Sugars; Carbohydrates; Chemistry Techniques, Synthetic; Cycloaddition Reaction; Glycosides; Heterocyclic Compounds; Humans; Morpholines; Nucleosides; Pyrroles; Stereoisomerism; Sulfones; Triazoles | 2020 |
More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells.
Topics: Adverse Outcome Pathways; Carcinoma, Hepatocellular; Cell Line, Tumor; Dioxolanes; Dioxoles; Fatty Acids; Fatty Liver; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Models, Theoretical; Pesticides; Pyrroles; Triazoles; Triglycerides | 2021 |
Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata.
Topics: Administration, Topical; Alopecia Areata; Animals; Azetidines; CD8-Positive T-Lymphocytes; Cytokines; Isonicotinic Acids; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Macrophages; Mice, Inbred C3H; Nitriles; NK Cell Lectin-Like Receptor Subfamily K; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |
Rhodium-Catalyzed Denitrogenative Transannulation of
Topics: Catalysis; Glycosides; Molecular Structure; Pyrroles; Rhodium; Triazoles | 2021 |
Synthesis and structure-activity relationship studies of 1,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 1 (JAK1) inhibitors.
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Models, Molecular; Molecular Structure; Pyrimidines; Pyrroles; Structure-Activity Relationship; Triazoles | 2022 |
Selective Orexin Receptor Antagonists as Novel Augmentation Treatments for Major Depressive Disorder: Evidence for Safety and Efficacy From a Phase 2B Study of Seltorexant.
Topics: Adult; Depressive Disorder, Major; Humans; Orexin Receptor Antagonists; Pyrimidines; Pyrroles; Triazoles | 2022 |
Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.
Topics: Acetamides; Animals; Antifungal Agents; Ascomycota; Drug Discovery; Drug Evaluation, Preclinical; Fenbendazole; Madurella; Moths; Mycetoma; Neglected Diseases; Piperazines; Pyrimidines; Pyrroles; Thiazoles; Triazoles | 2022 |
Ion-Pairing Assemblies of Anion-Responsive π-Electronic Systems Bearing Triazole Moieties Introduced by Click Chemistry.
Topics: Anions; Azides; Click Chemistry; Crystallography, X-Ray; Electronics; Pyrroles; Triazoles | 2022 |
Azirine-triazole hybrids: selective synthesis of 5-(2
Topics: Azides; Azirines; Ketones; Pyridines; Pyrroles; Triazoles | 2022 |
Substituent-Controllable Cascade Regioselective Annulation of
Topics: Catalysis; Pyrroles; Rhodium; Triazoles | 2023 |