Compounds > pyrroles
Page last updated: 2024-08-18

pyrroles and tomaymycin

pyrroles has been researched along with tomaymycin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gairola, C; Hurley, LH; Zmijewski, M1
Gairola, C; Hurley, LH1
Davey, CL; Jenkins, TC; Jones, GB; Kamal, A; Kneale, GG; Neidle, S; Thurston, DE; Webster, GD1
Hopfinger, AJ; Mabilia, M; Remers, WA1
Barcella, S; Corcoran, KE; Gregson, SJ; Howard, PW; Hurst, AA; Jenkins, TC; Kelland, LR; Thurston, DE; Yasin, MM1
Gazak, R; Janata, J; Kadlcik, S; Kamenik, Z; Kuzma, M; Palanova, L; Vobruba, S1
Bauer, A; Blankenfeldt, W; Dausend-Werner, S; Fayad, AA; Hoffmann, M; Müller, R; Pippel, J; von Tesmar, A1

Other Studies

7 other study(ies) available for pyrroles and tomaymycin

ArticleYear
Pyrrolo(1,4)benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules.
    Biochimica et biophysica acta, 1977, Apr-04, Volume: 475, Issue:3

    Topics: Anthramycin; Antibiotics, Antineoplastic; Benzodiazepinones; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; DNA; Drug Stability; Hydrogen-Ion Concentration; Models, Chemical; Polydeoxyribonucleotides; Proteins; Pyrroles; RNA; Thymus Gland

1977
Pyrrolo (1,4) benzodiazepine antitumor antibiotics: Biosynthetic studies on the conversion of tryptophan to the anthranilic acid moieties of sibiromycin and tomaymycin.
    Antimicrobial agents and chemotherapy, 1979, Volume: 15, Issue:1

    Topics: Antibiotics, Antineoplastic; Benzodiazepinones; ortho-Aminobenzoates; Pyrroles; Streptomyces; Tryptophan

1979
The non-covalent interaction of pyrrolo[2, 1-c] [1, 4]benzodiazepine-5, 11-diones with DNA.
    Anti-cancer drug design, 1990, Volume: 5, Issue:3

    Topics: Anthramycin; Antibiotics, Antineoplastic; Benzodiazepinones; Chemical Phenomena; Chemistry; Computer Simulation; DNA; Drug Interactions; Pyrroles; Stereoisomerism; Structure-Activity Relationship

1990
Conformations of complexes between pyrrolo[1,4]benzodiazepines and DNA segments.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:12

    Topics: Anthramycin; Base Sequence; Benzodiazepinones; Chemical Phenomena; Chemistry; DNA; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pyrroles

1986
Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines.
    Bioorganic & medicinal chemistry letters, 2000, Aug-21, Volume: 10, Issue:16

    Topics: Animals; Antibiotics, Antineoplastic; Benzodiazepines; Benzodiazepinones; DNA; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Ovarian Neoplasms; Pyrroles; Tumor Cells, Cultured

2000
Diversity of Alkylproline Moieties in Pyrrolobenzodiazepines Arises from Postcondensation Modifications of a Unified Building Block.
    ACS chemical biology, 2017, 08-18, Volume: 12, Issue:8

    Topics: Antineoplastic Agents; Benzodiazepines; Benzodiazepinones; Biological Products; Chemistry, Pharmaceutical; Molecular Structure; Pyrroles

2017
Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System.
    Cell chemical biology, 2017, Oct-19, Volume: 24, Issue:10

    Topics: Benzodiazepines; Benzodiazepinones; Models, Molecular; Peptide Synthases; Protein Domains; Pyrroles; Substrate Specificity

2017