Page last updated: 2024-08-18

pyrroles and thromboxane b2

pyrroles has been researched along with thromboxane b2 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's1 (7.14)18.2507
2000's7 (50.00)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grose, JH; Lacourcière, Y; Lebel, M1
Hirschfeld, DR; Maloney, PJ; Martinez, GR; Rosenkranz, RP; Walker, KA; Yang, DS1
Bullingham, RE; Forbes, CD; Greer, IA; Lloyd, J; McLaren, M; Spowart, K1
Belogi, L; Mezzadri, CM; Tubaro, E1
Laufer, S; Neupert, W; Tries, S1
Cerletti, C; Evangelista, V; Krauze-Brzósko, K; Manarini, S; Rotondo, S1
Gunasekera, SP; Hall, ML; Lynch, SM; Mayer, AM; Pomponi, SA; Sennett, SH1
Egido, J; Gómez-Gerique, JA; Gómez-Hernández, A; González, A; Ortega, L; Sánchez-Galán, E; Tuñón, J; Vidal, C1
Arima, J; Iguro, Y; Kariyazono, H; Masuda, H; Nakamura, K; Sakata, R; Yamada, K1
Gao, Y; Kastrissios, H; Moberly, J; Rohatagi, S; Salazar, D; Takahashi, M; Truitt, K; Wada, R; Xu, J; Yoshihara, K; Zhang, N1
Adámek, T; Alusik, S; Lejsková, M; Paluch, Z1
Auteri, A; Ciabattoni, G; Ciani, F; Davì, G; Ferrante, E; Ghezzi, A; Lattanzio, S; Liani, R; Pasqui, AL; Puccetti, L; Santilli, F; Scarpini, F1
Ajamieh, H; Chen, J; Chu, E; Farrell, G; Teoh, N; Wong, HJ; Yu, J1
Lin, Z; Tong, B; Xie, L; Xu, C1

Trials

4 trial(s) available for pyrroles and thromboxane b2

ArticleYear
Effect of short-term administration of cromakalim on renal hemodynamics and eicosanoid excretion in essential hypertension.
    American journal of hypertension, 1991, Volume: 4, Issue:9

    Topics: Adult; Antihypertensive Agents; Atrial Natriuretic Factor; Benzopyrans; Blood Pressure; Chlorides; Cromakalim; Dinoprost; Dinoprostone; Eicosanoids; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Potassium; Prostaglandins; Pyrroles; Regional Blood Flow; Renin-Angiotensin System; Sodium; Thromboxane B2; Time Factors; Vascular Resistance

1991
Haemostatic effects of ketorolac with and without concomitant heparin in normal volunteers.
    Thrombosis and haemostasis, 1988, Dec-22, Volume: 60, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Bleeding Time; Drug Therapy, Combination; Factor Xa; Hemostatics; Heparin; Humans; Ketorolac; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Pyrroles; Serine Proteinase Inhibitors; Thromboxane B2; Tolmetin

1988
Effects of atorvastatin and aspirin combined therapy on inflammatory responses in patients undergoing coronary artery bypass grafting.
    Cytokine, 2006, Volume: 36, Issue:5-6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antithrombins; Aspirin; Atorvastatin; Blood Platelets; Cholesterol; Coronary Artery Bypass; Cytokines; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Inflammation; Male; Middle Aged; P-Selectin; Pyrroles; Receptors, Cytokine; Thrombin; Thromboxane B2; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2006
Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia.
    Atherosclerosis, 2011, Volume: 214, Issue:1

    Topics: 3' Untranslated Regions; Anticholesteremic Agents; Atorvastatin; Blood Platelets; Double-Blind Method; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Oxidative Stress; Platelet Activation; Polymorphism, Genetic; Prospective Studies; Prostaglandins A; Pyrimidines; Pyrroles; Regression Analysis; Rosuvastatin Calcium; Sulfonamides; Thromboxane B2

2011

Other Studies

10 other study(ies) available for pyrroles and thromboxane b2

ArticleYear
[(1H-imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitors.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Animals; Aorta; Biological Availability; Blood Platelets; Chemical Phenomena; Chemistry; Humans; Imidazoles; Inflammation; Kidney Diseases; Male; Mice; Microsomes; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1989
Anti-inflammatory and antiplatelet effects of amtolmetin guacyl, a new gastroprotective non-steroidal anti-inflammatory drug.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Body Weight; Bone Density; Carrageenan; Dose-Response Relationship, Drug; Exudates and Transudates; Glycine; In Vitro Techniques; Indomethacin; Male; Piroxicam; Platelet Aggregation; Platelet Aggregation Inhibitors; Pleurisy; Pyrroles; Rats; Thromboxane B2

2001
The mechanism of action of the new antiinflammatory compound ML3000: inhibition of 5-LOX and COX-1/2.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:3

    Topics: Acetates; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Thromboxane B2

2002
Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
    European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3

    Topics: Acetates; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epinephrine; Humans; In Vitro Techniques; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrroles; Quinolines; Thrombin; Thromboxane B2

2004
Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines.
    BMC pharmacology, 2005, Mar-11, Volume: 5

    Topics: Animals; Animals, Newborn; Carbazoles; Carbolines; Haliclona; Indoles; L-Lactate Dehydrogenase; Microglia; Pyrroles; Rats; Structure-Activity Relationship; Superoxides; Thromboxane B2

2005
Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Acetates; Animals; Atherosclerosis; Chemokine CCL2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Leukotriene B4; Lipids; Lipoxygenase Inhibitors; Macrophages; Male; NF-kappa B; Pyrroles; Rabbits; RNA, Messenger; Thromboxane B2; Tunica Intima

2007
Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:3

    Topics: Administration, Oral; Adult; Algorithms; Asian People; Clinical Trials, Phase I as Topic; Cyclooxygenase 2 Inhibitors; Data Interpretation, Statistical; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Models, Biological; Pyrroles; Randomized Controlled Trials as Topic; Software; Sulfonamides; Thromboxane B2; Time Factors; White People

2007
The inhibitory effect of statins on urinary 11-dehydrothromboxane levels.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:3

    Topics: Aged; Aspirin; Atorvastatin; Biomarkers; Blood Glucose; Blood Platelets; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Czech Republic; Down-Regulation; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Simvastatin; Thromboxane B2; Time Factors; Treatment Outcome; Triglycerides

2010
Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:8

    Topics: Administration, Oral; Animals; Atorvastatin; Cell Adhesion Molecules; Cytokines; Cytoprotection; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Enzyme Activation; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Liver; Male; Mice; Mice, Obese; NF-kappa B; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Reperfusion Injury; RNA, Messenger; Thromboxane B2; Time Factors; Toll-Like Receptor 4

2012
[Atorvastatin inhibits platelet aggregation and activation following carotid balloon injury in cholesterol-fed rabbits].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:8

    Topics: Animals; Atorvastatin; Blood Platelets; Carotid Artery Injuries; Cholesterol; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; P-Selectin; Platelet Activation; Platelet Aggregation; Pyrroles; Rabbits; Thromboxane B2

2014