pyrroles has been researched along with thromboxane a2 in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 18 (78.26) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deguchi, K; Komada, F; Morita, K; Nishikawa, M; Shirakawa, S | 1 |
| McLeod, JD; Piper, PJ | 1 |
| Taira, N; Yamagishi, T; Yanagisawa, T | 1 |
| Deguchi, K; Nishikawa, M; Saitoh, M; Shirakawa, S | 1 |
| Hirschfeld, DR; Maloney, PJ; Martinez, GR; Rosenkranz, RP; Walker, KA; Yang, DS | 1 |
| Shikada, K; Tanaka, S | 2 |
| Fujikura, N; Kawamura, N; Masuda, Y; Tanaka, S; Yamashita, T | 1 |
| Mellemkjaer, S; Nielsen-Kudsk, JE | 1 |
| Eichinger, MR; Russ, RD; Walker, BR | 1 |
| Högestätt, ED; Ryman, T; Zygmunt, PM | 1 |
| O'Brien, E; Wanstall, JC | 1 |
| Angus, JA; Fujiwara, T | 1 |
| Hüsken, BC; Pfaffendorf, M; Timmenga, EJ; Van Zwieten, PA; Vroom, MB | 1 |
| Matsuo, K; Oda, M; Yamashita, A; Yokota, K | 1 |
| McPherson, GA; Piekarska, AE | 1 |
| Choi, RT; Iskander, MN; Kong, DC; McPherson, GA | 1 |
| Akar, F; Aşlamaci, S; Kanzik, I; Köksoy, C; Tufan, H; Uydeş-Dogan, BS | 1 |
| Champion, HC; Kadowitz, PJ | 1 |
| Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S | 1 |
| Chen, CL; Lo, HM; Tsai, YJ; Wu, PH; Wu, WB | 1 |
| Fuset, MP; Moscardó, A; Ruano, M; Santos, MT; Valles, J | 1 |
| Latorre, A; Madrid, I; Moscardó, A; Santos, MT; Vallés, J | 1 |
1 trial(s) available for pyrroles and thromboxane a2
| Article | Year |
|---|---|
Effect of atorvastatin on platelet thromboxane A(2) synthesis in aspirin-treated patients with acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Atorvastatin; Blood Platelets; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Pyrroles; Thromboxane A2; Treatment Outcome | 2009 |
22 other study(ies) available for pyrroles and thromboxane a2
| Article | Year |
|---|---|
Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinases; Pyrroles; Quinolones; Thromboxane A2 | 1992 |
Effect of K+ channel-modulating drugs on the vasoconstrictor responses of leukotrienes C4, D4 and angiotensin II in the guinea-pig isolated perfused heart.
Topics: Angiotensin II; Animals; Benzopyrans; Charybdotoxin; Cromakalim; Galanin; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Nitroglycerin; Peptides; Potassium Channels; Pyrroles; Radioimmunoassay; Scorpion Venoms; SRS-A; Thromboxane A2; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilator Agents | 1992 |
Activation of phospholipase C by the agonist U46619 is inhibited by cromakalim-induced hyperpolarization in porcine coronary artery.
Topics: Animals; Benzopyrans; Calcium; Coronary Vessels; Cromakalim; Enzyme Activation; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Muscle Contraction; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Swine; Thromboxane A2; Type C Phospholipases | 1992 |
[Intracellular actions of antiplatelet drugs which affect cyclic AMP metabolism in platelets--their effects on Ca2+ mobilization and protein phosphorylation in human platelets].
Topics: Alprostadil; Blood Platelets; Calcium; Carbazoles; Colforsin; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Pyrroles; Thromboxane A2 | 1990 |
[(1H-imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitors.
Topics: Animals; Aorta; Biological Availability; Blood Platelets; Chemical Phenomena; Chemistry; Humans; Imidazoles; Inflammation; Kidney Diseases; Male; Mice; Microsomes; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1989 |
K+ channel openers produce epithelium-dependent relaxation of the guinea-pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Benzopyrans; Cromakalim; Epithelium; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea; Vasoactive Intestinal Peptide | 1995 |
Comparative study of vasodilator effects of the potassium channel openers NIP-121 and levcromakalim in dogs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Benzopyrans; Coronary Circulation; Cromakalim; Dogs; Female; Hemodynamics; Male; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Glibenclamide inhibits hypoxic relaxation of isolated porcine coronary arteries under conditions of impaired glycolysis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Deoxyglucose; Endothelium, Vascular; Glyburide; Glycolysis; Hypoxia; In Vitro Techniques; Indomethacin; Isometric Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Swine; Theophylline; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Potassium channels are not involved in vasopressin-induced vasodilation in the rat lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Arginine Vasopressin; Barium; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Kinetics; Lung; Male; Muscle, Smooth, Vascular; Nitroarginine; Potassium Channel Blockers; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pyrroles; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1994 |
Regional differences in endothelium-dependent relaxation in the rat: contribution of nitric oxide and nitric oxide-independent mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta; Arginine; Benzopyrans; Calcimycin; Calcitonin Gene-Related Peptide; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Histamine; Ionophores; Liver; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Renal Artery; Thromboxane A2; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1995 |
Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Epithelium; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Melitten; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Phospholipases A; Phospholipases A2; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea | 1996 |
In vitro hypoxia on rat pulmonary artery: effects on contractions to spasmogens and role of KATP channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim; Drug Interactions; Glyburide; Hypoxia; In Vitro Techniques; Male; Potassium Channel Blockers; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adolescent; Adult; Arteries; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Humans; In Vitro Techniques; Methacholine Chloride; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Skin; Thromboxane A2; Vasoconstrictor Agents | 1995 |
The mechanism of action of KBT-3022, a new antiplatelet agent.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arachidonic Acid; Blood Platelets; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Guinea Pigs; In Vitro Techniques; Intramolecular Oxidoreductases; Isomerases; Male; Phosphatidic Acids; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rabbits; Thiazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 1997 |
Structure-activity relationship of quaternary ion antagonism of levcromakalim-induced relaxation in pig coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Chemical Phenomena; Chemistry, Physical; Coronary Vessels; Cromakalim; Guanethidine; In Vitro Techniques; Ions; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Quaternary Ammonium Compounds; Structure-Activity Relationship; Swine; Tetraphenylborate; Thromboxane A2; Uncoupling Agents; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
The thromboxane A2 and K(ATP) channel antagonist actions of a series of sulphonylurea derivatives in the pig coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Glyburide; Onium Compounds; Organophosphorus Compounds; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Structure-Activity Relationship; Swine; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
The comparison of the responsiveness of human isolated internal mammary and gastroepiploic arteries to levcromakalim: an alternative approach to the management of graft spasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Benzopyrans; Coronary Artery Bypass; Cromakalim; Endothelin-1; Female; Glyburide; Humans; In Vitro Techniques; Indomethacin; Male; Mammary Arteries; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Omentum; Potassium; Potassium Channel Blockers; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Stomach; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Albuterol; Alprostadil; Analysis of Variance; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Bradykinin; Cats; Cromakalim; Endothelium, Vascular; Female; Glyburide; Heart Rate; Hindlimb; Hydrazines; Isradipine; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Nitroprusside; Norepinephrine; Penicillamine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; S-Nitroso-N-Acetylpenicillamine; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Thromboxane A2; Vasoactive Intestinal Peptide; Vasodilation; Vasodilator Agents | 1997 |
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors | 2006 |
Thrombin induces cyclooxygenase-2 expression and prostaglandin E2 release via PAR1 activation and ERK1/2- and p38 MAPK-dependent pathway in murine macrophages.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Flavonoids; Imidazoles; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrroles; Quinazolines; Receptor, PAR-1; Signal Transduction; Thrombin; Thromboxane A2 | 2009 |
Reduction of platelet cytosolic phospholipase A2 activity by atorvastatin and simvastatin: biochemical regulatory mechanisms.
Topics: Anticholesteremic Agents; Aspirin; Atorvastatin; Blood Platelets; Calcium; Collagen; Cyclooxygenase 1; Drug Combinations; Drug Synergism; Heptanoic Acids; Humans; Mitogen-Activated Protein Kinases; Phospholipase A2 Inhibitors; Phospholipases A2; Phosphorylation; Platelet Aggregation; Pravastatin; Pyrroles; Simvastatin; Thromboxane A2; Thromboxane-A Synthase | 2013 |