pyrroles has been researched along with thiophenes in 273 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (13.55) | 18.7374 |
| 1990's | 42 (15.38) | 18.2507 |
| 2000's | 69 (25.27) | 29.6817 |
| 2010's | 106 (38.83) | 24.3611 |
| 2020's | 19 (6.96) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T | 1 |
| Binder, D; Chocholous, J; Habison, G; Noe, CR | 1 |
| Cecil, JT; Chib, JS; Nigrelli, RF; Ruggieri, GD; Stempien, MF | 1 |
| Boykin, DW; Das, BP | 1 |
| Blanton, CD; Briggs, FH; Pelletier, WT | 1 |
| Bryan, GT; Chiu, CW; Michie, PD; Muraoka, K; Wang, CY | 1 |
| Freeman, F; Kazan, BH; Wilson, PL | 1 |
| Bryan, GT; Muraoka, K; Wang, CY | 1 |
| Labitzke, H; Reisch, J | 1 |
| Clifton, PG; Lee, MD | 1 |
| Bansinath, M; Puig, MM; Ramabadran, K; Turndorf, H | 1 |
| Cowan, A; Wheeler-Aceto, H | 2 |
| Bansinath, M; Ramabadran, K; Shukla, VK; Turndorf, H | 1 |
| Bianchi, G; Colombo, M; La Regina, A; Petrillo, P; Tavani, A | 1 |
| Connor, DT; Conroy, MC; Kennedy, JA; Mullican, MD; Sorenson, RJ; Thueson, DO | 1 |
| Baldwin, BA; Ebenezer, IS; Forsling, ML; Parrott, RF | 1 |
| Echevarria, E; Hughes, J; Hunter, JC; Robles, L; Tortella, FC | 1 |
| Dissanayake, VU; Hill, RG; Hughes, J; Hunter, JC | 1 |
| Cowan, A; Ianone, M; Porreca, F; Wheeler, H | 1 |
| Bianchi, G | 1 |
| Alvinerie, M; Buéno, L; Gué, M; Junien, JL | 1 |
| Boyle, SJ; Hughes, J; Hunter, JC; Meecham, KG | 1 |
| Hill, RG; Hughes, J; Johnson, MA; Leighton, GE; Meecham, KG | 1 |
| Hewson, G; Hill, RG; Hughes, J; Leighton, GE; Turner, WD | 1 |
| Birchmore, B; Clark, CR; Hill, RG; Hughes, J; Hunter, JC; Sharif, NA | 1 |
| Hill, RG; Hughes, J; Leighton, GE | 2 |
| Artico, M; Corelli, F; Fanini, D; Giorgi, R; Massa, S; Palumbo, G; Pantaleoni, GC; Stefancich, G | 1 |
| Galdino, SL; Luu-Duc, C; Pitta, IR | 1 |
| Biniecki, S; Herold, F | 1 |
| Freiter, E; Humphries, AJ; Keener, RL; Skelton, FS; Snyder, HR; Yano, K | 1 |
| Fang, VS | 2 |
| Berk, S; Gisser, H | 1 |
| Albrecht, R | 1 |
| Baker, AD; Betteridge, D; Kemp, NR; Kirby, RE | 1 |
| Fang, VS; Goldhaber, P; Tashjian, AH | 1 |
| Kay, IT; Punja, N | 1 |
| Dunoff, RY; Graboyes, H; Jaffe, G; Karash, CB; Pachter, IJ; Snader, K; Weinstock, J | 1 |
| Griffin, CE; Martin, KR; Peller, RP; Peters, JA | 1 |
| Babudieri, B; Gualtieri, F; Riccieri, FM | 1 |
| Anderson, WK; Jones, AN | 1 |
| Hayes, ES; Pugsley, MK; Saint, DA; Walker, MJ | 1 |
| Bian, SS; Chen, YL; Lee, H | 1 |
| Blanchard, JC; Carruette, A; Garret, C; Laduron, PM; Montier, F; Moussaoui, SM | 1 |
| Cheung, WM; Damiano, BP; Salata, JJ; Stump, GL | 1 |
| Carruette, A; Garret, C; Moussaoui, S | 1 |
| Diop, L; Junien, JL; Langlois, A; Pascaud, X; Rivière, PJ | 1 |
| Coenen, A; Lasoń, W; Machelska, H; Przewłocka, B; Przewłocki, R; van Luijtelaar, G | 1 |
| Bansinath, M; Shukla, VK; Turndorf, H | 1 |
| Nagasaka, H; Yaksh, TL | 1 |
| Lasoń, W; Machelska, H; Przewłocka, B | 1 |
| Besley, W; Gray, G; Nolan, AM; Reid, J | 1 |
| Genovese, RF; Moreton, JE; Tortella, FC | 1 |
| Addo, MF; Falotico, R; Giardino, E; Haertlein, BJ; Katz, LB; Loughney, D; McNally, JJ; Press, JB; Sanfilippo, PJ | 1 |
| Headley, PM; Herrero, JF | 1 |
| Falotico, R; Giardino, EC; Katz, LB; Moore, JB; Salata, JJ | 1 |
| de Costa, BR; Haaseth, RC; Horan, PJ; Hruby, VJ; Porreca, F; Rice, K | 1 |
| Magyar, A; Medzihradszky, K; Rónai, AZ | 1 |
| Jacoby, HI; Lee, DK; Steffler, C; Tomko, KA | 1 |
| Grouhel, A; Wettstein, JG | 1 |
| Walker, MJ; Walker, ML; Wall, RA | 1 |
| Battistini, L; Casiraghi, G; Gaetani, E; Rassu, G; Zanardi, F | 1 |
| Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ | 1 |
| Kasuga, M; Liu, BF; Miyata, S; Ohara, T; Oimomi, M; Shoda, H; Suzuki, K; Yamada, H | 1 |
| Hughes, J; Hunter, JC; Moreton, JE; Robles, L; Rose, J; Tortella, FC | 1 |
| DeCoster, MA; Tortella, FC | 1 |
| Antoon, JS; Perry, MA; Walker, JS; Wilson, JL | 1 |
| Goldin, AL; Pugsley, MK | 2 |
| Blair, JB; Kanthasamy, A; Lucaites, VL; Marona-Lewicka, D; Nelson, DL; Nichols, DE | 1 |
| Albright, JD; Aranapakam, V; Chan, PS; Coupet, J; Grosu, GT; Mazandarani, H; Ru, X; Saunders, T | 1 |
| Holtzman, SG; Powell, KR | 1 |
| Alkan, S; Hepuzer, Y; Toppare, L; Yagci, Y | 1 |
| Sheridan, RD | 1 |
| Dunsch, L; Fáber, R; Neudeck, A; Nuyken, O; Rapta, P | 1 |
| Dabrowski, A; Kamieńska-Trela, K; Wójcik, J | 1 |
| Acquotti, D; Auzzas, L; Battistini, L; Casiraghi, G; Marzocchi, L; Pinna, L; Rassu, G; Zanardi, F | 1 |
| Dannhardt, G; Fiebich, B; Kiefer, W; Krämer, G; Maehrlein, S; Nowe, U | 1 |
| Hayakawa, A; Muratake, H; Natsume, M | 1 |
| Bhargava, A; Bombara, M; Caringal, Y; Dally, R; Dumas, J; Gunn, D; Housley, TJ; Johnson, JS; Kingery-Wood, J; Lee, W; Osterhout, M; Paulsen, H; Ranges, GE; Redman, AM; Renick, J; Scott, WJ; Shrikhande, A; Smith, RA; Swartz, S; Wild, H; Wilhelm, SM; Young, D | 1 |
| Bergman, J; Carey, GJ | 1 |
| Baurin, N; Chavatte, P; Lesieur, D; Marot, C; Yous, S | 1 |
| Carlson, KE; Katzenellenbogen, BS; Katzenellenbogen, JA; Mortensen, DS; Rodriguez, AL; Sun, J | 1 |
| Corso, G; de Nucci, G; Eberlin, MN; Ifa, DR; Moraes, LA; Ribeiro, W; Salmon, J | 1 |
| Latos-Grazyński, L; Sprutta, N | 1 |
| Dalvie, DK; Kalgutkar, AS; Khojasteh-Bakht, SC; O'Donnell, JP; Obach, RS | 1 |
| Gullapalli, S; Ramarao, P | 1 |
| Aburel, PS; Bayón, P; Jørgensen, KA; Saaby, S | 1 |
| Lee, KG; Ochi, H; Shibamoto, T; Yanagimoto, K | 1 |
| Abe, S; Hiyoshi, H; Ikuta, H; Ito, M; Kurusu, N; Okada, T; Saeki, T; Shinmyo, D; Tanaka, H; Tanaka, K; Yanagimachi, M; Yasuda, N; Yoshida, I | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Ogawa, K; Rasmussen, SC | 1 |
| Alkan, S; Cirpan, A; Hepuzer, Y; Toppare, L; Yagci, Y | 1 |
| Burcl, R; Carter, S; Handy, NC | 1 |
| Pellegrino, J | 1 |
| Bergers, G; Hanahan, D | 1 |
| Innis, PC; Wallace, GG | 1 |
| Banes, AK; Watts, SW | 1 |
| Buu-Hoi, NP; Chevance, LG; Gazave, JM; Pillot, J; Xuong, ND | 1 |
| HASSELQUIST, H; VON EULER, H | 1 |
| BIEL, JH; HOYA, WK; LEISER, HA; MITCHELL, TF; ROBERTSON, JE | 1 |
| Cavanni, P; Di Fabio, R; Donati, D; Faedo, S; Gehanne, S; Maffeis, M; Marchioro, C; Micheli, F; Sabbatini, FM; Tarzia, G; Tranquillini, ME; Viziano, M | 1 |
| An, D; Cho, WS; Lynch, V; Sessler, JL | 1 |
| Fishbein, JC; Johnson, JK; Kensler, TW; Kwak, MK; Navamal, M; Petzer, JP | 1 |
| Goud, PS; Hegde, P; Kumar, MP; Kumar, PR; Raju, S; Reddy, GO; Reddy, VV; Sailaja, M; Sarma, MR; Suresh, T | 1 |
| Laustsen, G; Wimmett, L | 1 |
| Baraldi, PG; Borgatti, M; Carrion, MD; Gambari, R; Heilmann, J; Iaconinoto, MA; Romagnoli, R; Tabrizi, MA | 1 |
| Ehara, M; Nakatsuji, H; Ohtsuka, Y; Takahashi, M; Udagawa, Y | 1 |
| Amelichev, SA; Konstantinova, LS; Lyssenko, KA; Rakitin, OA; Rees, CW | 1 |
| Durdaği, S; Karalti, O; Salzner, U | 1 |
| Decker, M; El-Subbagh, H; Hoefgen, B; Kassack, MU; Lehmann, J; Mohr, P; Rostom, SA; Rudolf, DR; Schramm, AM; Schweikert, PM | 1 |
| Baron, O; Ila, H; Knochel, P; Wagner, AJ | 1 |
| Abbas, I; Danil de Namor, AF; Hammud, HH | 1 |
| Dodd, MC; Ward, WC | 1 |
| Chandrashekar, TK; Goswami, D; Joshi, BS; Nag, A; Prabhuraja, V; Rath, H | 1 |
| Itami, K; Noyori, R; Sudo, T; Yanagisawa, S | 1 |
| Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ | 1 |
| Namvar, A; Warriner, K | 1 |
| Akhmedov, NG; Akhmedova, RG; Doskocz, J; Hall, CD; Katritzky, AR; Majumder, S | 1 |
| Fujiwara, T; Harada, Y; Hirao, I; Kawai, R; Kimoto, M; Mitsui, T; Sato, A; Yokoyama, S | 1 |
| Liu, J; Woodson, M | 1 |
| Dervan, PB; Doss, RM; Foister, S; Marques, MA | 1 |
| Dohi, T; Goto, A; Kita, Y; Kiyono, Y; Maruyama, A; Morimoto, K; Takenaga, N; Tohma, H | 1 |
| Billingsley, K; Buchwald, SL | 1 |
| Golab, M; Skwarlo-Sonta, K | 1 |
| Hayashi, M; Matsumoto, K; Shindo, M; Shishido, K; Soejima, H; Yoshikawa, T; Yoshimura, Y | 1 |
| Boyukbayram, AE; Sahmetlioglu, E; Toppare, L; Yagci, Y; Yildiz, HB | 1 |
| Bard, J; Chopra, R; Cowling, R; Fobare, WF; Hu, Y; Jin, G; Malamas, MS; Manas, E; Robichaud, AJ; Solvibile, WR; Turner, J; Wagner, E | 1 |
| Jia, Z; Li, Y; Misra, HP; Trush, MA; Zhu, H | 1 |
| Arnould, JC; Boutron, P; Delouvrié, B; Dossetter, AG; Foote, KM; Hamon, A; Hancox, U; Harris, CS; Hutton, M; Lamorlette, M; Matusiak, Z | 1 |
| Demoustier-Champagne, S; Gence, L; Hofkens, J; Hu, Z; Jonas, AM; Melinte, S; Muls, B; Nysten, B; Serban, DA | 1 |
| Aleman, C; Zanuy, D | 1 |
| Chen, A; Gao, M; Pan, Y; Wang, Z; Wu, A; Yin, G | 1 |
| Fukunaga, R; Harada, Y; Hirao, I; Yokoyama, S | 1 |
| Bag, S; Degani, MS; Tawari, NR | 1 |
| Loew, LM; Wei, M; Xie, A; Yan, P | 1 |
| Goodsaid, FM | 1 |
| Brandt, JT; Ernest, CS; Farid, NA; Jakubowski, JA; Konkoy, CS; Li, YG; Payne, CD; Salazar, DE; Small, DS; Winters, KJ | 1 |
| Brandon, NJ; Hinchliffe, RM; Huszar, SL; Hutson, PH; Jacobson, MA; Jones, B; Kandebo, M; McNaughton, CH; Mullins, CM; Pascarella, DM; Sachs, N; Smith, SM; Sparey, T; Surles, NO; Uslaner, JM; Venkatraman, S; Yao, L; Young, MB | 1 |
| De Nanteuil, G; Gloanec, P; Golsteyn, RM; Hickman, J; Parmentier, JG; Pierré, A; Portevin, B | 1 |
| Dohi, T; Goto, A; Ito, M; Kita, Y; Morimoto, K; Ogawa, C | 1 |
| Dohi, T; Fujioka, H; Kita, Y; Morimoto, K; Ogawa, C | 1 |
| Williams, M | 1 |
| Aponick, A; Li, CY; Malinge, J; Marques, EF | 1 |
| Baraldi, PG; Boger, DL; Cara, CL; Hwang, I; Lajiness, JP; MacMillan, KS; Robertson, WM; Romagnoli, R | 1 |
| Cresteil, T; Dallemagne, P; Legay, R; Perri, V; Rault, S; Rochais, C; Sopkova-de Oliveira Santos, J | 1 |
| Kelesidis, I; Kelesidis, T | 1 |
| Cheng, Y; Li, JQ; Peng, JH | 1 |
| Salzner, U | 1 |
| Ellinger, Y; Guillemin, JC; Lattelais, M; Matrane, A | 1 |
| Schneider, EH; Seifert, R; Strasser, A; Thurmond, RL | 1 |
| Buszewski, B; Ligor, T; Nowaczyk, J; Olszowy, P; Szultka, M | 1 |
| Buszewski, B; Fuchs, P; Kegler, R; Miekisch, W; Mundkowski, R; Olszowy, P; Schubert, J; Szultka, M | 1 |
| Harries, M; Ward, SE | 1 |
| Cailly, T; Charnay, Y; Dumas, N; Fabis, F; Lemaître, S; Millet, P; Rault, S | 1 |
| Hernández-Trujillo, J; Sánchez-Mendoza, E | 1 |
| Guerra, D; Restrepo, A; Ripoll, JD; Serna, A | 1 |
| Foley-Comer, AJ; Jordan, P; Russell-Yarde, F; Young, AM | 1 |
| Aptula, AO; Schultz, TW; Sparfkin, CL | 1 |
| Balzarini, J; Dezhenkova, LG; Glazunova, VA; Huang, HS; Preobrazhenskaya, MN; Shchekotikhin, AE; Shevtsova, EK; Shtil, AA; Traven', VF | 1 |
| Lau, KC; Lo, PK | 1 |
| Bruns, CJ; Facchetti, A; Loser, S; Marks, TJ; Miyauchi, H; Ortiz, RP; Stupp, SI | 1 |
| Bocian, S; Buszewski, B; Ligor, T; Olszowy, P; Szultka, M | 1 |
| Boerner, JL; Bohin, N; Ge, Y; Irwin, ME; Mueller, KL | 1 |
| Luo, SC; Peng, H; Travas-Sejdic, J; Yu, HH | 1 |
| Pingale, SS | 1 |
| Anthopoulos, TD; Ashraf, RS; DeLongchamp, DM; Fischer, DA; Geerts, YH; Hammond, MR; Heeney, M; Kline, RJ; McCulloch, I; Richter, LJ; Schroeder, B; Smith, JN; Toney, MF; Zhang, X | 1 |
| Buszewski, B; Nowaczyk, J; Olszowy, P; Szultka, M | 1 |
| Ai, X; Qian, J; Yang, H; Zhou, M | 1 |
| Bai, R; Bolognesi, A; Brancale, A; Coluccia, A; Dondio, G; Ferlini, C; Gatti, V; Granata, I; Hamel, E; Iannitto, ML; La Regina, G; Lavecchia, A; Lavia, P; Maresca, B; Mariani, M; Mercurio, C; Novellino, E; Piscitelli, F; Porta, A; Rensen, W; Santoni, A; Silvestri, R; Soriani, A; Varasi, M | 1 |
| Janssen, RA; Karsten, BP; Smith, PP; Tamayo, AB | 1 |
| Kang, SG; Kim, SG; Lee, WH; Lee, YH; Lee, YS | 1 |
| Cherian, C; Gangjee, A; Hou, Z; Kugel Desmoulin, S; Matherly, LH; Mitchell-Ryan, S; Wang, L | 1 |
| Balaz, S; Bergeron, C; Natesan, S; Subramaniam, R | 1 |
| Gao, W; Pei, A; Ponedal, A; Sattayasamitsathit, S; Uygun, A; Wang, J | 1 |
| Buszewski, B; Jackowski, M; Szeliga, J; Szultka, M | 1 |
| Barraza, SJ; Blakely, PK; Bolduc, KL; Irani, DN; Keep, RF; Larsen, SD; Miller, DJ; Sindac, JA; Yestrepsky, BD | 1 |
| Furlan, A; Gevaerts, VS; Janssen, RA; Turbiez, M; Wienk, MM | 1 |
| Buszewski, B; Jeżewska, A; Olszowy, P; Szultka, M | 1 |
| Gasperi, T; Loreto, MA; Migliorini, A; Oliviero, C | 1 |
| Noé, MS; Ríos, AC; Tor, Y | 1 |
| Chen, H; Gao, D; Guo, Y; Liu, H; Liu, Y; Yu, G; Zhang, J; Zhao, Y | 1 |
| Fujisaki, Y; Nishida, J; Suna, Y; Yamashita, Y | 1 |
| Cherian, C; Desmoulin, SK; Gangjee, A; Hou, Z; Kushner, J; Matherly, LH; Polin, L; Stout, M; Wang, L; White, K | 1 |
| Borrelli, G; Borsini, F; Brindisi, M; Butini, S; Cabri, W; Campiani, G; Caprioli, A; Di Serio, S; Fezza, F; Gallo, G; Gemma, S; Maccarrone, M; Maramai, S; Minetti, P; Ros, S; Stasi, MA; Talamonti, E; Vincenti, S | 1 |
| Forcelli, PA; Gale, K; Kammerich, AD; Kayinamura, YP; Lee, BC; Rubinson, JF; Rubinson, LH; Sweeney, CT | 1 |
| Ajayaghosh, A; Anees, P; Anupama, VN; Divya, KP; Jayamurthy, P; Mathew, J; Philips, DS; Sreejith, S | 1 |
| Bian, YJ; Huang, ZZ; Mao, XR; Xiang, CB | 1 |
| Li, B; Luo, Y; Tan, B; Wang, W; Wu, K | 1 |
| Martin, NH; Robinson, JD | 1 |
| Chen, W; Schuster, GB | 1 |
| Jin, R; Sun, W; Tang, S | 1 |
| Ayub, K; Iaroshenko, VO; Iqbal, J; Langer, P; Nisa, RU; Salman, GA | 1 |
| Braunschweig, H; Damme, A; Hörl, C; Jimenez-Halla, JO; Krummenacher, I; Kupfer, T; Mailänder, L; Radacki, K | 1 |
| Becka, M; Kubitza, D; Mueck, W; Roth, A | 1 |
| Esrafilzadeh, D; Moulton, SE; Razal, JM; Stewart, EM; Wallace, GG | 1 |
| Li, X; Li, Y; Tan, L; Tang, T; Wang, J; Wu, Y; Xu, Z; Yang, P; Zhao, L; Zhao, Z | 1 |
| Janssen, RA; Kirkus, M; Meskers, SC | 1 |
| Bettega, MH; Kossoski, F | 1 |
| Horner, KE; Karadakov, PB | 1 |
| Ando, K; Iyoda, M; Kageyama, T; Koizumi, M; Nishinaga, T; Takase, M | 1 |
| Heeger, AJ; Jiang, L; Su, B; Wu, Y | 1 |
| Bu, L; Gao, J; Liu, F; Russell, TP; Wang, C; Wang, H; Wei, W | 1 |
| Fadda, AA; Refat, HM | 1 |
| Bakhshi, AK; Thakral, P | 1 |
| Jin, R; Luo, D; Tang, S | 1 |
| Gladow, D; Reissig, HU | 1 |
| Li, Z; Lu, G; Zhang, X | 1 |
| Grubbs, RB; Nam, CY; Park, YS; Wu, Q | 1 |
| Archana, S; Deora, GS; Kolli, SK; Kulkarni, P; Medisetti, R; Nakhi, A; Pal, M; Ramesh Raju, R; Saridena, M; Yellanki, S | 1 |
| Bhosale, SV; Bilic, A; Chellappan, V; Gupta, A; Patil, H; Rananaware, A; Sonar, P; Zu, WX | 1 |
| Bai, S; Hor, TS; Liu, X; Shen, C; Sun, Q; Zhang, P | 1 |
| Zhang, Q; Zhao, G; Zhou, H | 1 |
| Furukawa, K; Furuyama, T; Kobayashi, N; Maruyama, Y; Matano, Y; Nakano, H; Omomo, S | 1 |
| Jin, YH; Jin, Z; Kim, S; Lee, G; Park, CS; Park, YS | 1 |
| Bharatam, PV; Dhaked, DK; Kantevari, S; Kumar, CD; Lokesh, P; Sarma, AV; Sirisha, K; Sripadi, P | 1 |
| Ak, M; Ayranci, R; Demirkol, DO; Timur, S | 1 |
| Brindha Devi, P; Janupally, R; Jeankumar, VU; Kulkarni, P; Medepi, B; Sriram, D; Suryadevara, P; Yogeeswari, P | 1 |
| Bao, M; Feng, X; Yamamoto, Y; Yu, X; Zhang, S | 1 |
| Ben Ammar, H; Ben Hassine, B; Doucet, H; Hfaiedh, A; Soulé, JF; Yuan, K | 1 |
| Guan, X; Pan, S; Shao, C; Shi, G; Zhang, Y | 1 |
| Abraham, S; Hayes, ES; Pugsley, MK; Saint, DA; Walker, MJ | 1 |
| Acevedo-Rocha, CG; Schulze-Makuch, D | 1 |
| Dann, CE; Deis, SM; Gangjee, A; George, C; Hou, Z; Kushner, J; Matherly, LH; Mitchell-Ryan, S; O'Connor, C; Orr, S; Polin, L; Raghavan, S; Wallace, A; Wang, L; White, K; Wilson, MR; Yang, S | 1 |
| Lourens, AC; Minders, C; Petzer, A; Petzer, JP | 1 |
| Black, DS; Griffith, R; Kumar, N; Kutty, SK; Lewis, PJ; Ma, C; Mielczarek, M; Thach, O; Yang, X | 1 |
| Blankenfeldt, W; Drees, SL; Empting, M; Fetzner, S; Hartmann, RW; Maurer, CK; Weidel, E; Witzgall, F; Zender, M | 1 |
| Gong, X; Li, J; Liang, X; Liu, Z; Ma, Y; Qing, W; Tan, L; Wang, Y; Yang, S | 1 |
| Abadi, AH; Abouzid, KA; Allarà, M; Di Marzo, V; Klein, CD; Ligresti, A; Osman, NA; Rabbito, A | 1 |
| Lee, C; Lee, J; Nam, SY; Park, S; Suh, DH; Yoon, SC | 1 |
| Dürüst, Y; Karakuş, H | 1 |
| Balachandran, S; Mohanan, PV; Philip, JE; Prathapachandra Kurup, MR; Shanty, AA; Sneha, EJ | 1 |
| Camurlu, P; Cevik, E; Dervisevic, E; Dervisevic, M; Senel, M; Yildiz, HB | 1 |
| Aydemir, N; Baek, P; Barker, D; Chan, E; Travas-Sejdic, J; Williams, DE | 1 |
| Chang, K; Chen, H; Fang, X; Gao, D; Li, D; Men, X; Wu, C; Yin, S; Yuan, Z; Zhang, J; Zhang, X; Zhou, L | 1 |
| Haniuda, M; Hosokawa, Y; Hyodo, T; Karnan, S; Konishi, H; Ota, A; Tsuzuki, S; Wahiduzzaman, M; Yamaji, M | 1 |
| Cao, H; Gao, Y; Jiang, X; Liu, Y; Qu, Z; Sun, H | 1 |
| Bömer, U; Brohm, D; Collin, MP; Grünewald, S; Héroult, M; Hess-Stumpp, H; Hübsch, W; Jautelat, R; Lobell, M; Lustig, K; Schirok, H; Vöhringer, V | 1 |
| Demizu, Y; Eto, R; Kurihara, M; Misawa, T; Naito, M; Noguchi-Yachide, T; Ohoka, N; Tanaka, M | 1 |
| Chen, R; Gao, Y; Hu, P; Jiang, J; Liu, X; Wang, H; Zeng, G; Zhang, D | 1 |
| Ding, S; Dong, H; Hu, M; Hu, W; Li, J; Liu, F; Ni, Z; Qiu, G; Ye, J; Zhang, X | 1 |
| Abraham, S; Adaikan, G; Beatch, GN; Goldin, AL; Hayes, ES; MacLeod, BA; Pugsley, MK; Saint, DA; Walker, MJA; Wall, RA | 1 |
| Bay-Jensen, AC; Hägglund, P; Karsdal, MA; Kayed, A; Kjelgaard-Petersen, CF; Mobasheri, A; Sharma, N; Thudium, CS | 1 |
| Culver, EW; Rasmussen, SC; Wolfe, RMW | 1 |
| Bender, S; Boemer, U; Collin, MP; Ellinghaus, P; Grünewald, S; Héroult, M; Hess-Stumpp, H; Ince, S; Kneip, C; Kopitz, C; Lustig, K; Mumberg, D; Politz, O; Thuss, U; Ziegelbauer, K; Zopf, D | 1 |
| Fu, X; Lisak, G; Talikowska, M | 1 |
| Baskić, D; Bogdanović, GA; Bugarčić, Z; Janković, N; Joksimović, N; Matić, S; Petronijević, J; Popović, S; Todorović, D; Tot, A; Vraneš, M | 1 |
| Naing, A | 1 |
| Bender, S; Boix, O; Cassier, PA; Cathomas, R; Cho, BC; Ellinghaus, P; Gajate, P; Grevel, J; Joerger, M; Navarro, A; Nogai, H; Nogova, L; Ocker, M; Park, SH; Penel, N; Rajagopalan, P; Richly, H; Sayehli, CM; Schostak, M; Schuler, M; Soo, RA; Tai, D | 1 |
| Alvarado-Canché, C; De-León, A; Gallardo-Vega, C; Jiménez-Cárdenas, P; Ledezma-Pérez, A; Martínez-Cartagena, M; Romero-García, J | 1 |
| Feng, K; Guo, H; Guo, X; Ling, S; Liu, J; Shi, Y; Sun, H; Tang, L; Tang, Y; Uddin, MA; Wang, Y; Woo, HY; Yang, K; Zhang, S; Zhang, Y | 1 |
| Cadarso, VJ; Dervisevic, E; Dervisevic, M; Dyson, J; Easton, CD; Esser, L; Senel, M; Voelcker, NH | 1 |
| Bowen, JP; Güner, OF; Matesic, DF; Uko, NE | 1 |
| Dong, X; Li, B; Shao, J; Xue, L; Yang, N; Yang, X; Yu, Q | 1 |
| Andreeva, DV; Dezhenkova, LG; Kaluzhny, DN; Litvinova, VA; Moisenovich, MM; Ramonova, AA; Schols, D; Shchekotikhin, AE; Shtil, AA; Tikhomirov, AS; Treshalin, ID; Tsvetkov, VB; Volodina, YL | 1 |
| Arnaboldi, S; Benincori, T; Bonetti, G; Cirilli, R; Gupta, B; Kuhn, A | 1 |
| Gahan, CG; Lyons, T; O'Sullivan, TP | 1 |
| Asgharinezhad, AA; Ebrahimzadeh, H | 1 |
| Chen, X; Cheng, S; Dai, X; Ding, L; Guo, H; Guo, Q; Wang, J; Wang, T; Xu, X; Zhang, W | 1 |
| Al-Obaidy, KI; Cheng, L | 1 |
| Hubert, P; Loriot, Y; Selmani, Z; Thiery-Vuillemin, A | 1 |
| Bahtiar, A; Fujio, Y; Kametani, Y; Kobayashi, A; Maeda, M; Matsumoto, K; Miyake, Y; Mori, S; Obana, M; Tanaka, S; Tomimatsu, M; Wahyuni, T; Yamamoto, A | 1 |
| Boccellato, C; Fullstone, G; Idbaih, A; Juric, V; Kolbe, E; Lamfers, MLM; Murphy, BM; Peters, N; Rehm, M; Verreault, M | 1 |
| Suni, II | 1 |
| Arnaboldi, S; Benincori, T; Bichon, S; Bonetti, G; Cirilli, R; Garrigue, P; Gounel, S; Karajić, A; Kuhn, A; Mano, N; Salinas, G | 1 |
| Buś-Kwaśnik, K; Gilant, E; Kutner, A; Kutner, W; Maciejewska, D; Noworyta, KR; Rybakiewicz-Sekita, R; Żołek, T | 1 |
| Bhattarai, DP; Jang, SR; Kaliannagounder, VK; Kim, CS; Park, J; Rezk, AI; Yoon, D | 1 |
| Addeo, A; Alborelli, I; Calgua, B; Fernandez, E; Früh, M; Haefliger, S; Holer, L; Jermann, PM; Joerger, M; Mach, N; Mark, M; Mauti, L; Rothschild, SI; Savic-Prince, S; Schneider, M; Waibel, C | 1 |
| Barbatti, M; do Casal, MT; Plasser, F; Toldo, JM | 1 |
| Borodina, TN; Korchevin, NA; Manuilov, VV; Nikonova, VS; Rozentsveig, IB; Smirnov, VI; Ushakov, IA | 1 |
| Gunbas, G; Karabag, A; Soylemez, S; Soyler, D; Toppare, L; Udum, YA | 1 |
13 review(s) available for pyrroles and thiophenes
| Article | Year |
|---|---|
Kappa opioids: therapeutic considerations in epilepsy and CNS injury.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Benzofurans; Central Nervous System Diseases; Epilepsy; Humans; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Thiophenes | 1994 |
Biotransformation reactions of five-membered aromatic heterocyclic rings.
Topics: Animals; Cytochrome P-450 Enzyme System; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Indoles; Isoxazoles; Models, Chemical; Molecular Structure; Oxadiazoles; Oxazoles; Pyrazoles; Pyrroles; Tetrazoles; Thiadiazoles; Thiazoles; Thiophenes; Triazoles; Xenobiotics | 2002 |
The use of conducting polymers in membrane-based separations: a review and recent developments.
Topics: Aniline Compounds; Chemistry Techniques, Analytical; Electrochemistry; Ions; Membranes, Artificial; Models, Chemical; Polymers; Pyrroles; Thiophenes | 2003 |
Inherently conducting polymer nanostructures.
Topics: Aniline Compounds; Colloids; Crystallization; Electric Conductivity; Electrochemistry; Emulsions; Nanotechnology; Polymers; Pyrroles; Semiconductors; Thiophenes | 2002 |
2004 drug approval highlights: FDA update.
Topics: Administration, Cutaneous; Amlodipine; Anti-Bacterial Agents; Antidepressive Agents; Bronchodilator Agents; Cardiovascular Agents; Drug Approval; Drug Combinations; Duloxetine Hydrochloride; Eplerenone; Estradiol; Excitatory Amino Acid Antagonists; Female; Gastrointestinal Agents; Heptanoic Acids; Humans; Ketolides; Male; Memantine; Osteoporosis, Postmenopausal; Pyrroles; Rifamycins; Rifaximin; Scopolamine Derivatives; Spironolactone; Thiophenes; Tiotropium Bromide; United States | 2005 |
Functional nanostructures from surface chemistry patterning.
Topics: Biosensing Techniques; Dimethylpolysiloxanes; DNA; Genomics; Gold; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanostructures; Nanotechnology; Nylons; Polymers; Proteomics; Pyrroles; Quantum Theory; Surface Properties; Thiophenes; Titanium | 2007 |
Recent advances in the discovery of selective AMPA receptor positive allosteric modulators.
Topics: Allosteric Regulation; Benzamides; Drug Evaluation, Preclinical; Pyrazoles; Pyrroles; Receptors, AMPA; Sulfonamides; Thiazoles; Thiophenes | 2010 |
Recent advances in C-S bond formation via C-H bond functionalization and decarboxylation.
Topics: Carbon; Catalysis; Hydrogen; Metal Nanoparticles; Metals; Nanotechnology; Pyrroles; Sulfur; Thiophenes | 2015 |
Application of conducting polymers to wound care and skin tissue engineering: A review.
Topics: Aniline Compounds; Animals; Bandages, Hydrocolloid; Biocompatible Materials; Electric Conductivity; Humans; Polymers; Pyrroles; Regeneration; Skin; Skin Physiological Phenomena; Thiophenes; Tissue Engineering; Tissue Scaffolds; Wound Healing | 2019 |
Akt Pathway Inhibitors.
Topics: Antineoplastic Agents; Benzylamines; Cell Line, Tumor; Diamines; Drug Design; Heterocyclic Compounds, 3-Ring; Humans; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Phospholipids; Piperazines; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Pyrroles; Quinoxalines; Signal Transduction; Structure-Activity Relationship; Sulfonamides; Thiadiazoles; Thiophenes | 2020 |
Structure-activity relationships of furanones, dihydropyrrolones and thiophenones as potential quorum sensing inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; Furans; Microbial Sensitivity Tests; Pyrroles; Quorum Sensing; Rhodophyta; Structure-Activity Relationship; Thiophenes | 2020 |
Fibroblast growth factor receptor (
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma; Exons; Gene Amplification; Gene Fusion; Genetic Predisposition to Disease; Humans; Molecular Targeted Therapy; Mutation, Missense; Phenotype; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 3; Thiophenes; Urinary Bladder Neoplasms; Urothelium | 2021 |
Substrate Materials for Biomolecular Immobilization within Electrochemical Biosensors.
Topics: Biosensing Techniques; Electric Conductivity; Electrochemical Techniques; Electrochemistry; Electrodes; Enzymes, Immobilized; Oxides; Polymers; Pyrroles; Reproducibility of Results; Thiophenes; Tin Compounds | 2021 |
5 trial(s) available for pyrroles and thiophenes
| Article | Year |
|---|---|
Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects.
Topics: Adolescent; Adult; Anticholesteremic Agents; Area Under Curve; Atorvastatin; Chromatography, Liquid; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Epistaxis; Heptanoic Acids; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Molecular Structure; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyrroles; Tandem Mass Spectrometry; Thiophenes; Ticlopidine; United Kingdom; Young Adult | 2008 |
Aleglitazar, a balanced PPARα/γ agonist, has no clinically relevant pharmacokinetic interaction with high-dose atorvastatin or rosuvastatin.
Topics: Adolescent; Adult; Aged; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Interactions; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Oxazoles; PPAR alpha; PPAR gamma; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Thiophenes; Young Adult | 2011 |
Absence of clinically relevant interactions between rivaroxaban--an oral, direct Factor Xa inhibitor--and digoxin or atorvastatin in healthy subjects.
Topics: Adult; Anti-Arrhythmia Agents; Atorvastatin; Cross-Over Studies; Digoxin; Drug Interactions; Drug Therapy, Combination; Factor Xa Inhibitors; Fibrinolytic Agents; Headache; Heptanoic Acids; Humans; Male; Middle Aged; Morpholines; Pyrroles; Rivaroxaban; Self Administration; Thiophenes; Young Adult | 2012 |
Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression: a phase 1 dose-escalation and dose-expansion study.
Topics: Acute Kidney Injury; Aged; Anorexia; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Diarrhea; Fatigue; Female; Humans; Hyperphosphatemia; Hypoglycemia; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Piperazines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Vomiting | 2019 |
Fibroblast growth factor receptor (FGFR) inhibitor rogaratinib in patients with advanced pretreated squamous-cell non-small cell lung cancer over-expressing FGFR mRNA: The SAKK 19/18 phase II study.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Piperazines; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Thiophenes | 2022 |
255 other study(ies) available for pyrroles and thiophenes
| Article | Year |
|---|---|
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase | 1981 |
[Thiophene as a structural element of physiologically active compounds, I: Synthesis of derivatives of 4-thieno[2,3-b]-pyrroleacetic acid (author's transl)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Pyrroles; Thiophenes | 1979 |
Physiologically active substances from marine sponges IV: Heterocyclic compounds.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Survival; Escherichia coli; Furans; Heterocyclic Compounds; Porifera; Pyrroles; Thiophenes | 1977 |
Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)thiophenes and -pyrroles.
Topics: Amidines; Animals; Antiprotozoal Agents; Mice; Plasmodium berghei; Pyrroles; Structure-Activity Relationship; Thiophenes; Trypanosoma | 1977 |
Pyrrole, furan, and thiophene oxamates as potential antiallergy agents.
Topics: Amino Acids; Animals; Furans; Oxamic Acid; Passive Cutaneous Anaphylaxis; Pyrroles; Rats; Thiophenes | 1978 |
Antibacterial activity of nitropyrroles, nitrothiphenes, and aminothiophenes in vitro.
Topics: Amines; Bacteria; Enterobacter; Escherichia coli; Nitro Compounds; Proteus vulgaris; Pseudomonas aeruginosa; Pyrroles; Staphylococcus aureus; Structure-Activity Relationship; Thiophenes | 1975 |
Trypanosoma cruzi: antimicrobial activity and strain differentiating properties of some five- and six-membered heterocyclic compounds on trypomastigotes.
Topics: Furaldehyde; Furans; Isoxazoles; Ketones; Nitrofurans; Nitrofurantoin; Oximes; Pyrroles; Thiophenes; Trypanocidal Agents; Trypanosoma cruzi | 1975 |
Mutagenicity of nitrofurans, nitrothiophenes, nitropyrroles, nitroimidazole, aminothiophenes, and aminothiazoles in Salmonella typhimurium.
Topics: Amines; DNA Repair; DNA, Bacterial; Heterocyclic Compounds; Mutagens; Nitro Compounds; Nitrofurans; Nitroimidazoles; Pyrroles; Salmonella typhimurium; Structure-Activity Relationship; Thiazoles; Thiophenes | 1975 |
[Synthesis and mass spectroscopic analysis of some tert.-butyl thienyl-, pyrrolyl- and furyl-carbamates (author's transl)].
Topics: Butanes; Carbamates; Furans; Mass Spectrometry; Pyrroles; Thiophenes | 1975 |
Free-feeding and free-drinking patterns of male rats following treatment with opiate kappa agonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Male; Pyrroles; Pyrrolidines; Rats; Receptors, Opioid, kappa; Thiophenes | 1992 |
Kappa-opiate agonist-induced inhibition of gastrointestinal transit in different strains of mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Gastrointestinal Transit; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Species Specificity; Thiophenes | 1991 |
Involvement of a peripheral component in the antinociceptive effects of opioids in a model of tonic pain.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Male; Morphine; Narcotics; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1990 |
Intracerebroventricular administration of kappa-agonists induces convulsions in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Baclofen; Benzeneacetamides; Benzomorphans; Cerebral Ventricles; Convulsants; Dizocilpine Maleate; Injections, Intraventricular; Ketamine; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Stereoisomerism; Thiophenes | 1991 |
In vitro binding profile and in vivo pharmacological properties of the K-opioid compound PD 117302.
Topics: Analgesia; Animals; Binding Sites; Brain; Culture Techniques; Diprenorphine; Diuresis; Dose-Response Relationship, Drug; Gastrointestinal Transit; Injections, Intravenous; Male; Naloxone; Pain Measurement; Pyrroles; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes | 1991 |
Novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles as potential antiallergy agents.
Topics: Basophils; Benzene Derivatives; Chemical Phenomena; Chemistry; Histamine H1 Antagonists; Histamine Release; Humans; Pyrroles; Structure-Activity Relationship; Tetrazoles; Thiophenes | 1991 |
Standardization of the rat paw formalin test for the evaluation of analgesics.
Topics: Analgesics; Animals; Aspirin; Behavior, Animal; Decerebrate State; Foot; Formaldehyde; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Reference Standards; Thiophenes | 1991 |
Hormonal effects of apomorphine and cholecystokinin in pigs: modification of the response to cholecystokinin by a dopamine antagonist (metoclopramide) and a kappa opioid agonist (PD117302).
Topics: Animals; Apomorphine; Cholecystokinin; Dopamine Antagonists; Feeding Behavior; Female; Hydrocortisone; Lypressin; Male; Metoclopramide; Pyrroles; Swine; Thiophenes | 1991 |
PD117302, a selective non-peptide opioid kappa agonist, protects against NMDA and maximal electroshock convulsions in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Electroshock; Flurothyl; Male; N-Methylaspartate; Pyrroles; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes; Time Factors | 1990 |
Characterization of kappa-opioid receptors in the guinea-pig ileum.
Topics: Animals; Benzeneacetamides; Benzomorphans; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Naloxone; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes | 1990 |
Comparison of PD 117302, a kappa agonist, and morphine on colonic transit and formalin-induced pain in rats.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Formaldehyde; Gastrointestinal Transit; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes | 1989 |
High-performance liquid chromatographic assay of k-opioid selective benzeneacetamide derivatives (U50488, U69593 and PD117302) in rat plasma and brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzeneacetamides; Brain Chemistry; Chromatography, High Pressure Liquid; Male; Pyrroles; Pyrrolidines; Rats; Receptors, Opioid; Thiophenes | 1989 |
Stimulation of kappa opiate receptors in intestinal wall affects stress-induced increase of plasma cortisol in dogs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acoustic Stimulation; Administration, Oral; Animals; Corticotropin-Releasing Hormone; Dogs; Hydrocortisone; Injections, Intraventricular; Intestines; Male; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stress, Psychological; Thiophenes | 1989 |
An in vitro profile of activity for the (+) and (-) enantiomers of spiradoline and PD117302.
Topics: Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Pyrroles; Pyrrolidines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Thiophenes; Vas Deferens | 1989 |
Pharmacological profile of PD 117302, a selective kappa-opioid agonist.
Topics: Analgesics; Animals; Depression, Chemical; Diuretics; Gastrointestinal Motility; Injections, Intravenous; Male; Mice; Pain; Pyrroles; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Respiration; Substance-Related Disorders; Thiophenes | 1987 |
The kappa agonists PD117302 and U50488 produce a biphasic effect on 24 hour food intake in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Eating; Male; Narcotics; Pyrroles; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes | 1987 |
PD117302: a selective agonist for the kappa-opioid receptor.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pyrroles; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes; Vas Deferens | 1988 |
The effects of the kappa agonist PD-117302 on feeding behaviour in obese and lean Zucker rats.
Topics: Animals; Eating; Feeding Behavior; Hyperphagia; Male; Obesity; Pyrroles; Rats; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes | 1988 |
Effects of 5-HT and alpha 1 adrenoceptor antagonists on kappa opioid-induced sedation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; Prazosin; Pyrroles; Pyrrolidines; Receptors, Opioid; Serotonin; Serotonin Antagonists; Thiophenes | 1988 |
[Non-steroidal anti-inflammatory agents. IV. Synthesis and pharmacologic activity of aroylthiopheneacetic acids with a pyrrole group].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Pyrroles; Rats; Rats, Inbred Strains; Thiophenes | 1986 |
[Benzylidene-5 pyrrolones, furanones and thiophenones. 2. Quantitative structure-activity relationship].
Topics: Antifungal Agents; Benzylidene Compounds; Chemical Phenomena; Chemistry; Fungi; Furans; Microbial Sensitivity Tests; Pyrroles; Structure-Activity Relationship; Thiophenes | 1986 |
[Synthesis of meso-N, N'-bis(pyridalo)-,N, N'-bis(2-furfurylideno)-,N, N'-bis(2-pyrrolideno)-,N, N'-bis(2-thenylideno)-1,2-diphenylethylenediamines and meso-N-pyridalo-,N-(2-furfurylideno)-,N-(2-pyrrolideno)-N-(2-thenylideno)-N-benzoyl-1, 2-diphenylethyle
Topics: Chemical Phenomena; Chemistry; Ethylenediamines; Furans; Hydrogenation; Hydrolysis; Indicators and Reagents; Pyridines; Pyrroles; Schiff Bases; Spectrophotometry, Infrared; Thiophenes | 1974 |
The synthesis of 6-substituted thieno(3,2-b)pyrroles. Analogs of tryptophan, tryptamine, and indoleacetic acid.
Topics: Indoleacetic Acids; Pyrroles; Thiophenes; Tryptamines; Tryptophan | 1972 |
Studies on the hypocalcemic action of 2-pyrrolecarboxylic acid.
Topics: Administration, Oral; Animals; Calcitonin; Calcium; Carboxylic Acids; Diet; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Male; Nephrectomy; Parathyroid Hormone; Phosphates; Proline; Pyrroles; Rats; Thiophenes | 1973 |
Radiation chemistry of nitrogen and sulfur heterocyclics.
Topics: Chromatography, Gas; Free Radicals; Heterocyclic Compounds; Imidazoles; Nitrogen; Pyrazines; Pyrazoles; Pyrimidines; Pyrroles; Radiochemistry; Sulfur; Tetrazoles; Thiazoles; Thiophenes; Triazines; Triazoles | 1973 |
[Investigations about the antibacterial activity of quinolonecarboxylic acids. II. Synthesis of I-ethyl-4-quinolone-3-carboxylic acids with fused five-membered heterocyclic rings].
Topics: Anti-Infective Agents; Carboxylic Acids; Furans; Ketones; Pyrroles; Quinolines; Thiophenes | 1972 |
Application of photoelectron spectrometry to pesticide analysis. Photoelectron spectra of five-membered heterocycles and related molecules.
Topics: Bridged-Ring Compounds; Cyclopentanes; Furans; Oxazoles; Pesticides; Photometry; Pyrazoles; Pyrroles; Spectrum Analysis; Thiophenes | 1970 |
5-membered heterocyclic compounds: a new class of hypocalcemic agents.
Topics: Bone and Bones; Calcium; Culture Techniques; Hypocalcemia; Nephrectomy; Phosphorus; Pyrroles; Thiophenes | 1970 |
The synthesis of potential insecticides. 3. Carbamic esters of 3-cyano-4-hydroxy-thiophens and -pyrroles.
Topics: Carbamates; Cholinesterase Inhibitors; Cyanates; Insecticides; Pyrroles; Thiophenes | 1970 |
Pteridines. 8. Some 2,4,7-triamino-6-heteroarylpteridines.
Topics: Chromatography, Paper; Furans; Hydrogen-Ion Concentration; Imidazoles; Oxazoles; Pteridines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Spectrum Analysis; Thiazoles; Thiophenes; Triazoles; Ultraviolet Rays | 1968 |
Salicylate hypoglycemic action in alloxan-diabetic rats and structural relationships.
Topics: Animals; Benzene Derivatives; Blood Glucose; Diabetes Mellitus, Experimental; Female; Heterocyclic Compounds; Male; Mass Screening; Nicotinic Acids; Pyrazines; Pyridinium Compounds; Pyrimidines; Pyrroles; Rats; Salicylates; Thiophenes | 1968 |
Preparation and ultraviolet spectra of tri-2-heteroarylphosphine oxides.
Topics: Chemical Phenomena; Chemistry; Furans; Oxides; Phosphines; Pyrroles; Thiophenes | 1965 |
[Research in the field of substances with antiviral action. Derivatives of nitrothienyl- and nitropyrrolylglyoxyals].
Topics: Antiviral Agents; In Vitro Techniques; Pyrroles; Salmonella; Staphylococcus; Thiophenes; Viruses | 1965 |
Synthesis and evaluation of furan, thiophene, and azole bis[(carbamoyloxy)methyl] derivatives as potential antineoplastic agents.
Topics: Animals; Antineoplastic Agents; Carbamates; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Furans; Indicators and Reagents; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Pyrroles; Spectrophotometry; Structure-Activity Relationship; Thiophenes | 1984 |
Do related kappa agonists produce similar effects on cardiac ion channels?
Topics: Animals; Anti-Arrhythmia Agents; Benzofurans; Blood Pressure; Electric Stimulation; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Ion Channels; Male; Myocardium; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stereoisomerism; Thiophenes | 1995 |
Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test.
Topics: Animals; Biotransformation; CHO Cells; Cricetinae; Furans; Heterocyclic Compounds; Imidazoles; Maillard Reaction; Mutagenicity Tests; Mutagens; Pyrazines; Pyridines; Pyrroles; Salmonella typhimurium; Sister Chromatid Exchange; Sulfur Compounds; Thiazoles; Thiophenes | 1994 |
A non-peptide NK1-receptor antagonist, RP 67580, inhibits neurogenic inflammation postsynaptically.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Capsaicin; Electric Stimulation; Indoles; Inflammation; Injections, Intravenous; Isoindoles; Male; Morphine; Mucus; Nasal Mucosa; Pyrroles; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Synapses; Thiophenes; Xylenes | 1993 |
In vivo cardiac electrophysiologic effects of RWJ 29009, a new potassium-channel activator, in comparison to cromakalim and nicardipine.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Cromakalim; Dogs; Electrocardiography; Female; Heart Conduction System; Male; Nicardipine; Piperidones; Potassium Channels; Pyrans; Pyrroles; Thiophenes; Vasodilator Agents | 1993 |
Further evidence that substance P is a mediator of both neurogenic inflammation and pain: two phenomena inhibited either by postsynaptic blockade of NK1 receptors or by presynaptic action of opioid receptor agonists.
Topics: Analgesics; Animals; Anticonvulsants; Electric Stimulation; Formaldehyde; Indoles; Inflammation; Isoindoles; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Thiophenes | 1993 |
Effect of fedotozine on the cardiovascular pain reflex induced by distension of the irritated colon in the anesthetized rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetates; Acetic Acid; Amino Acid Sequence; Anesthesia; Animals; Benzyl Compounds; Blood Pressure; Colon; Dose-Response Relationship, Drug; Male; Molecular Sequence Data; Pain; Propylamines; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex; Thiophenes | 1994 |
Kappa opioid receptor agonists suppress absence seizures in WAG/Rij rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Epilepsy, Absence; Injections, Intraventricular; Injections, Subcutaneous; Male; Molecular Sequence Data; Naltrexone; Pyrroles; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1995 |
Pertussis and cholera toxins modulate kappa-opioid receptor agonists-induced hypothermia and gut inhibition.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Body Temperature; Cholera Toxin; Digestive System; Dose-Response Relationship, Drug; Gastrointestinal Transit; Injections, Intraventricular; Male; Mice; Pertussis Toxin; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Thiophenes; Virulence Factors, Bordetella | 1995 |
Effects of intrathecal mu, delta, and kappa agonists on thermally evoked cardiovascular and nociceptive reflexes in halothane-anesthetized rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Anesthesia, Inhalation; Animals; Blood Pressure; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Halothane; Heart Rate; Hot Temperature; Injections, Spinal; Male; Morphine; Nalbuphine; Nociceptors; Pain Threshold; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Reflex; Thiophenes | 1995 |
Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse.
Topics: Analgesics; Animals; Benzeneacetamides; Brain; Injections, Intraperitoneal; Mice; Naltrexone; Pilocarpine; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Seizures; Thiophenes | 1994 |
The effects of butorphanol on locomotor activity in ponies: a preliminary study.
Topics: Animals; Butorphanol; Drug Combinations; Female; Horses; Male; Motor Activity; Naloxone; Pyrroles; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1994 |
Evaluation of neuroprotection and behavioral recovery by the kappa-opioid, PD117302 following transient forebrain ischemia.
Topics: Animals; Cell Death; Conditioning, Operant; Ischemic Attack, Transient; Male; Prosencephalon; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement Schedule; Thiophenes | 1994 |
Novel thieno[2,3-b]- and [3,4-b]pyrans as potassium channel openers. Thiophene systems--XVII.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Cromakalim; Drug Evaluation, Preclinical; Glyburide; Hypertension; In Vitro Techniques; Models, Molecular; Molecular Structure; Potassium Channels; Pyrroles; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thiophenes | 1993 |
Functional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Benzofurans; Blood Pressure; Decerebrate State; Male; Naloxone; Nociceptors; Piperazines; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord; Thiophenes | 1993 |
RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent.
Topics: Angina Pectoris; Animals; Antihypertensive Agents; Benzopyrans; Bronchoconstriction; Calcium Channel Blockers; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female; Ferrets; Gastrointestinal Motility; Guinea Pigs; Heart Atria; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; Papillary Muscles; Pilocarpine; Potassium Channels; Pyrans; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rubidium; Rubidium Radioisotopes; Thiophenes; Vasodilator Agents | 1993 |
Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse.
Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzodiazepines; Benzomorphans; Cyclohexanes; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Structure-Activity Relationship; Thiophenes | 1993 |
Kinetic parameters of antagonism by the delta opioid receptor selective peptide antagonist Boc-Tyr-Pro-Gly-Phe-Leu-Thr against selective and non-selective agonists in the mouse vas deferens.
Topics: Analgesics; Animals; Anticonvulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred Strains; Morphine Derivatives; Naltrexone; Oligopeptides; Pyrroles; Receptors, Opioid, delta; Thiophenes; Vas Deferens | 1993 |
Vasorelaxant effect of the potassium channel activator, RWJ 29009, is tissue selective.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; Femoral Artery; In Vitro Techniques; Male; Nicardipine; Nitroprusside; Piperidones; Potassium Channels; Pyrans; Pyrroles; Saphenous Vein; Thiophenes; Vasodilation; Vasodilator Agents | 1993 |
Opioid antagonist profile of SC nor-binaltorphimine in the formalin paw assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1996 |
Determination of an arylacetamide antiarrhythmic in rat blood and tissues using reversed-phase high-performance liquid chromatography.
Topics: Animals; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Pyrroles; Rats; Reproducibility of Results; Spectrophotometry, Ultraviolet; Thiophenes | 1996 |
Expeditious syntheses of sugar-modified nucleosides and collections thereof exploiting furan-, pyrrole-, and thiophene-based siloxy dienes.
Topics: Furans; Nucleosides; Pyrroles; Silicon Compounds; Stereoisomerism; Thiophenes | 1997 |
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1997 |
Inhibitory effects of tenilsetam on the Maillard reaction.
Topics: Animals; Aorta; Blood Glucose; Collagen; Deoxyglucose; Diabetes Mellitus, Experimental; Fructose; Glucose; Glycated Hemoglobin; Kidney Cortex; Macromolecular Substances; Maillard Reaction; Male; Muramidase; Norleucine; Piperazines; Psychotropic Drugs; Pyrroles; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Thiophenes | 1997 |
EEG spectral analysis of the neuroprotective kappa opioids enadoline and PD117302.
Topics: Animals; Benzofurans; Electroencephalography; Male; Narcotics; Neuroprotective Agents; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Thiophenes | 1997 |
Intercellular adhesion molecule-1 expression in adjuvant arthritis in rats: inhibition by kappa-opioid agonist but not by NSAID.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Intercellular Adhesion Molecule-1; Naproxen; Narcotics; Pyrroles; Rats; Rats, Inbred Lew; Receptors, Opioid, kappa; Thiophenes | 1998 |
Time- and voltage-dependent block of sodium channels expressed in Xenopus oocytes by RSD 921, a novel class I antiarrhythmic drug.
Topics: Animals; Anti-Arrhythmia Agents; Brain; Dose-Response Relationship, Drug; Electric Conductivity; Heart; In Vitro Techniques; Neurons; Pyrroles; Rats; Sodium Channel Blockers; Thiophenes; Time Factors; Xenopus laevis | 1998 |
Thieno[3,2-b]- and thieno[2,3-b]pyrrole bioisosteric analogues of the hallucinogen and serotonin agonist N,N-dimethyltryptamine.
Topics: Amphetamines; Animals; Cell Line; Cloning, Molecular; Cricetinae; Discrimination Learning; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; N,N-Dimethyltryptamine; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiophenes; Tryptamines | 1999 |
Molecular analysis of the Na+ channel blocking actions of the novel class I anti-arrhythmic agent RSD 921.
Topics: Animals; Anti-Arrhythmia Agents; Electric Stimulation; In Vitro Techniques; Ion Channel Gating; Muscle, Skeletal; Mutation; Myocardium; Neurons; Oocytes; Patch-Clamp Techniques; Pyrroles; Rats; RNA; Sodium Channel Blockers; Sodium Channels; Thiophenes; Transcription, Genetic; Xenopus laevis | 1999 |
4,10-dihydro-5H-thieno[3,2-c][1]benzazepine derivatives and 9,10-dihydro-4H-thieno[2,3-c][1]benzazepine derivatives as orally active arginine vasopressin receptor antagonists.
Topics: Administration, Oral; Animals; Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Fibroblasts; Inhibitory Concentration 50; Mice; Pyrroles; Structure-Activity Relationship; Thiophenes | 1999 |
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes | 1999 |
Immobilization of invertase in conducting thiophene-capped poly(methylmethacrylate)/polypyrrole matrices.
Topics: beta-Fructofuranosidase; Electric Conductivity; Electrolysis; Enzymes, Immobilized; Glycoside Hydrolases; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Polymers; Polymethyl Methacrylate; Pyrroles; Surface Properties; Temperature; Thiophenes | 1999 |
Quantification of state-dependent drug interactions with the sodium channel.
Topics: Anti-Arrhythmia Agents; Humans; Pyrroles; Sodium Channels; Thiophenes | 2000 |
In situ EPR and UV-vis spectroelectrochemistry of hole-transporting organic substrates.
Topics: Benzidines; Electrochemistry; Electrodes; Electron Spin Resonance Spectroscopy; Oxidation-Reduction; Polymers; Pyrroles; Spectrophotometry; Spectrophotometry, Ultraviolet; Thiophenes | 2000 |
NMR studies on derivatives of heteroaromatic compounds: exceptionally small carbon-carbon couplings, 1J(CC), in 2-lithiothiophene, 2-lithio-N-methylpyrrole and 2-lithiofuran.
Topics: Furans; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Organometallic Compounds; Pyrroles; Thiophenes | 2000 |
The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues.
Topics: Furans; Plants, Medicinal; Pyrroles; Thiophenes | 2000 |
The pyrrole moiety as a template for COX-1/COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Indomethacin; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Molecular Structure; Monocytes; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrroles; Sulfones; Thiophenes | 2000 |
Preparation of benzene, furan, and thiophene analogs of duocarmycin SA employing a newly-devised phenol-forming reaction.
Topics: Benzene; Duocarmycins; Furans; Indoles; Molecular Structure; Pyrroles; Spectrum Analysis; Thiophenes | 2000 |
p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
Topics: Arthritis; Enzyme Inhibitors; Furans; Humans; Inhibitory Concentration 50; Interleukin-6; Mitogen-Activated Protein Kinases; Molecular Structure; Osteoporosis; p38 Mitogen-Activated Protein Kinases; Pyrroles; Thiophenes; Tumor Cells, Cultured; Urea | 2001 |
Enadoline discrimination in squirrel monkeys: effects of opioid agonists and antagonists.
Topics: Animals; Benzofurans; Discrimination Learning; Dose-Response Relationship, Drug; Male; Nalbuphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Thiophenes | 2001 |
Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
Topics: Benzene Derivatives; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cyclopentanes; Imidazoles; Isoenzymes; Isoxazoles; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrroles; Quantitative Structure-Activity Relationship; Spiro Compounds; Thiophenes | 2001 |
Synthesis and biological evaluation of a novel series of furans: ligands selective for estrogen receptor alpha.
Topics: Animals; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Furans; Humans; Ligands; Models, Molecular; Phenols; Pyrroles; Radioligand Assay; Receptors, Estrogen; Sheep; Structure-Activity Relationship; Thiophenes; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Uterus | 2001 |
Determination of RSD921 in human plasma by high-performance liquid chromatography-tandem mass spectrometry using tri-deuterated RSD921 as internal standard: application to a phase I clinical trial.
Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Calibration; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Deuterium; Humans; Indicators and Reagents; Mass Spectrometry; Pyrroles; Quality Control; Reference Standards; Thiophenes | 2001 |
Figure-eight tetrathiaoctaphyrin and dihydrotetrathiaoctaphyrin.
Topics: Heterocyclic Compounds, 4 or More Rings; Magnetic Resonance Spectroscopy; Models, Molecular; Oxidation-Reduction; Porphyrins; Pyrroles; Sulfides; Thiophenes | 2001 |
L-type Ca2+ channel modulation by dihydropyridines potentiates kappa-opioid receptor agonist induced acute analgesia and inhibits development of tolerance in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Benzeneacetamides; Calcium Channels, L-Type; Cannabinoids; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Male; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Thiophenes | 2002 |
Optically active aromatic and heteroaromatic alpha-amino acids by a one-pot catalytic enantioselective addition of aromatic and heteroaromatic C-H bonds to alpha-imino esters.
Topics: Amino Acids; Catalysis; Chemistry, Organic; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Esters; Furans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Pyrroles; Stereoisomerism; Thiophenes | 2002 |
Antioxidative activity of heterocyclic compounds found in coffee volatiles produced by Maillard reaction.
Topics: Aldehydes; Antioxidants; Coffee; Furans; Heterocyclic Compounds; Maillard Reaction; Pyrazines; Pyrroles; Thiazoles; Thiophenes; Volatilization | 2002 |
Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes.
Topics: Animals; Atorvastatin; Benzylamines; Cells, Cultured; Cholesterol; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Hepatocytes; Heptanoic Acids; Lipid Metabolism; Male; Oxidation-Reduction; Pyrroles; Rats; Rats, Sprague-Dawley; Thiophenes; Triglycerides | 2003 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
A simple and efficient route to N-functionalized dithieno[3,2-b:2',3'-d]pyrroles: fused-ring building blocks for new conjugated polymeric systems.
Topics: Amines; Catalysis; Chemistry, Organic; Crystallography, X-Ray; Cyclization; Molecular Conformation; Palladium; Polymers; Pyrroles; Thiophenes | 2003 |
Immobilization of invertase in conducting copolymers of 3-methylthienyl methacrylate.
Topics: beta-Fructofuranosidase; Electrochemistry; Enzymes, Immobilized; Kinetics; Microscopy, Electron, Scanning; Polymethyl Methacrylate; Pyrroles; Sodium Dodecyl Sulfate; Surface Properties; Temperature; Thiophenes | 2003 |
Vibrational spectra of furan, pyrrole, and thiophene from a density functional theory anharmonic force field.
Topics: Furans; Models, Chemical; Models, Statistical; Models, Theoretical; Pyrroles; Software; Spectrophotometry; Thiophenes | 2003 |
Combining antiangiogenic agents with metronomic chemotherapy enhances efficacy against late-stage pancreatic islet carcinomas in mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Islet Cell; Chronotherapy; Indoles; Matrix Metalloproteinase Inhibitors; Mice; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Protease Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Thiophenes | 2002 |
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension.
Topics: Animals; Arteries; Desoxycorticosterone; Female; Gene Expression; Hypertension; Indoles; Male; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2B; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Chloride; Thiophenes; Vasoconstriction | 2003 |
[On the pharmacodynamic properties of gamma- (2,5-dimethyl-1-pyrryl) propyl 2-thenoate].
Topics: Pyrroles; Thiophenes | 1956 |
[Bis-reductones from the 2, 4-dihydroxy-2, 5-dicarboxylic acid esters of furans, thiophenes, N-phenylpyrroles and selenophenes].
Topics: Dicarboxylic Acids; Esters; Furans; Malondialdehyde; Pyrroles; Selenium; Thiophenes | 1956 |
HYPOTENSIVES. VI. DISUBSTITUTED ALKYLENEDIAMINES AND RELATED COMPOUNDS.
Topics: Amines; Antihypertensive Agents; Chemistry, Pharmaceutical; Dogs; Ethylenediamines; Pharmacology; Piperidines; Pyridines; Pyrroles; Rats; Research; Thiophenes | 1963 |
2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: an exploration of the role of the pyrrolic scaffold.
Topics: Analgesics, Non-Narcotic; Animals; Benzene Derivatives; Binding, Competitive; CHO Cells; Cricetinae; Esters; Inhibitory Concentration 50; Mice; Nociceptors; Pain Measurement; Pyrroles; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Structure-Activity Relationship; Thiophenes | 2003 |
Calix[2]bipyrrole[2]furan and calix[2]bipyrrole[2]thiophene: new pyrrolic receptors exhibiting a preference for carboxylate anions.
Topics: Anions; Calixarenes; Calorimetry; Carboxylic Acids; Furans; Molecular Structure; Pyrroles; Thiophenes; X-Ray Diffraction | 2003 |
Phase 2 enzyme induction by the major metabolite of oltipraz.
Topics: Animals; Blotting, Western; Cell Death; DNA-Binding Proteins; Enzyme Induction; Glutathione; Glutathione Transferase; Heme Oxygenase (Decyclizing); Luciferases; Methylation; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Prodrugs; Pyrazines; Pyrroles; Thiones; Thiophenes; Time Factors; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured | 2003 |
Synthesis and biological evaluation of thiophene [3,2-b] pyrrole derivatives as potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Female; Male; Piroxicam; Pyrroles; Rats; Rats, Wistar; Structure-Activity Relationship; Thiophenes | 2004 |
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.
Topics: Animals; Antineoplastic Agents, Alkylating; Benzofurans; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Imidazoles; Mice; Molecular Structure; Netropsin; Pyrazoles; Pyrroles; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured | 2005 |
Theoretical fine spectroscopy with symmetry-adapted-cluster configuration-interaction method: outer- and inner-valence ionization spectra of furan, pyrrole, and thiophene.
Topics: Algorithms; Cluster Analysis; Computer Simulation; Furans; Ions; Models, Chemical; Models, Molecular; Molecular Conformation; Pyrroles; Spectrum Analysis; Thiophenes | 2005 |
Direct synthesis of fused 1,2,3,4,5-pentathiepins.
Topics: Antifungal Agents; Catalysis; Chloroform; Crystallography, X-Ray; Molecular Structure; Pyrroles; Pyrrolidines; Stereoisomerism; Temperature; Thiepins; Thiophenes | 2005 |
Does the donor-acceptor concept work for designing synthetic metals? III. Theoretical investigation of copolymers between quinoid acceptors and aromatic donors.
Topics: Metals; Models, Chemical; Models, Molecular; Molecular Conformation; Polymers; Pyrazines; Pyrroles; Quinoxalines; Thiadiazoles; Thiophenes | 2006 |
Dopamine/serotonin receptor ligands. 10: SAR Studies on azecine-type dopamine receptor ligands by functional screening at human cloned D1, D2L, and D5 receptors with a microplate reader based calcium assay lead to a novel potent D1/D5 selective antagonist
Topics: Benzene Derivatives; Binding, Competitive; Calcium; Cell Line; Cloning, Molecular; Dopamine D2 Receptor Antagonists; Fluorometry; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Ligands; Pyrroles; Radioligand Assay; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D5; Structure-Activity Relationship; Thiophenes | 2006 |
Functionalized magnesium organometallics as versatile intermediates for the synthesis of polyfunctional heterocycles.
Topics: Antipyrine; Combinatorial Chemistry Techniques; Esters; Furans; Heterocyclic Compounds; Imidazoles; Imines; Iodides; Magnesium; Models, Chemical; Nitriles; Organometallic Compounds; Pyridines; Pyrroles; Quinolines; Thiazoles; Thiophenes; Uracil | 2006 |
Anion complexation by calix[3]thieno[1]pyrrole: the medium effect.
Topics: Acetonitriles; Anions; Calixarenes; Conductometry; Dimethyl Sulfoxide; Dimethylformamide; Formamides; Hydrocarbons, Halogenated; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphates; Propane; Pyrroles; Solvents; Thermodynamics; Thiophenes | 2006 |
A Comparative Study of the in Vitro Bacteriostatic Action of Some Simple Derivatives of Furan, Thiophene, and Pyrrole.
Topics: Furans; Humans; In Vitro Techniques; Pyrroles; Thiophenes | 1948 |
Aromatic core modified decaphyrins with the largest two-photon absorption cross-sections: syntheses and characterization.
Topics: Macromolecular Substances; Molecular Conformation; Molecular Structure; Pyrroles; Spectrophotometry, Ultraviolet; Thiophenes | 2006 |
Direct C-H arylation of (hetero)arenes with aryl iodides via rhodium catalysis.
Topics: Benzene Derivatives; Catalysis; Furans; Heterocyclic Compounds, 1-Ring; Iodobenzenes; Pyrroles; Rhodium; Thiophenes | 2006 |
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles | 2007 |
Microbial imprinted polypyrrole/poly(3-methylthiophene) composite films for the detection of Bacillus endospores.
Topics: Bacillus subtilis; Polymers; Pyrroles; Spores, Bacterial; Thiophenes | 2007 |
Structural elucidation of nitro-substituted five-membered aromatic heterocycles utilizing GIAO DFT calculations.
Topics: Algorithms; Heterocyclic Compounds, 1-Ring; Hydrocarbons, Aromatic; Imidazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrazoles; Pyrroles; Quantum Theory; Thiophenes | 2007 |
An unnatural base pair system for in vitro replication and transcription.
Topics: Base Pairing; DNA Replication; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Pyrimidines; Pyrroles; Templates, Genetic; Thiophenes; Transcription, Genetic; Viral Proteins | 2006 |
DNA minor-groove recognition by 3-methylthiophene/pyrrole pair.
Topics: Amino Acids, Aromatic; Binding Sites; DNA; Pyrroles; Thiophenes | 2004 |
Direct cyanation of heteroaromatic compounds mediated by hypervalent iodine(III) reagents: In situ generation of PhI(III)-CN species and their cyano transfer.
Topics: Cyanates; Free Radicals; Hydroxybenzoates; Iodine; Ligands; Molecular Structure; Oxidation-Reduction; Phenyl Ethers; Pyrroles; Thiophenes | 2007 |
Highly efficient monophosphine-based catalyst for the palladium-catalyzed suzuki-miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters.
Topics: Boronic Acids; Catalysis; Esters; Furans; Heterocyclic Compounds; Hydrocarbons, Halogenated; Indoles; Palladium; Phosphines; Pyridines; Pyrroles; Thiophenes | 2007 |
Mechanisms involved in the anti-inflammatory action of inhaled tea tree oil in mice.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Cell Count; Cyclooxygenase Inhibitors; Hypothalamo-Hypophyseal System; Immunologic Factors; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Biological; Peritoneal Cavity; Pituitary-Adrenal System; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Pyrroles; Reactive Oxygen Species; Receptors, Corticotropin-Releasing Hormone; Tea Tree Oil; Tetradecanoylphorbol Acetate; Thiophenes; Zymosan | 2007 |
Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates.
Topics: Furans; Heterocyclic Compounds; Molecular Structure; Pyrroles; Thiophenes | 2007 |
Immobilization of tyrosinase and alcohol oxidase in conducting copolymers of thiophene functionalized poly(vinyl alcohol) with pyrrole.
Topics: Alcohol Oxidoreductases; Catechols; Electrochemistry; Electrodes; Enzymes, Immobilized; Ethanol; Kinetics; Monophenol Monooxygenase; Polyvinyl Alcohol; Pyrroles; Substrate Specificity; Thiophenes | 2007 |
Thiophene substituted acylguanidines as BACE1 inhibitors.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Guanidines; Indicators and Reagents; Models, Molecular; Pyrroles; Structure-Activity Relationship; Thiophenes | 2007 |
Generation of superoxide from reaction of 3H-1,2-dithiole-3-thione with thiols: implications for dithiolethione chemoprotection.
Topics: Antineoplastic Agents; Chemoprevention; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Oxidation-Reduction; Oxygen Consumption; Pyrroles; Reactive Oxygen Species; Spin Trapping; Sulfhydryl Compounds; Superoxide Dismutase; Superoxides; Thioinosine; Thiones; Thiophenes | 2008 |
Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor.
Topics: Animals; Humans; Pyrroles; Rats; Receptors, LHRH; Structure-Activity Relationship; Thiophenes | 2007 |
High-throughput fabrication of organic nanowire devices with preferential internal alignment and improved performance.
Topics: Microarray Analysis; Microscopy, Atomic Force; Microscopy, Electron; Nanowires; Organic Chemicals; Pyrroles; Thiophenes | 2007 |
DNA-conducting polymer complexes: a computational study of the hydrogen bond between building blocks.
Topics: Computer Simulation; DNA; Hydrogen Bonding; Methylation; Models, Molecular; Molecular Structure; Nucleic Acids; Polymers; Pyrroles; Thiophenes | 2008 |
A new facile approach to the synthesis of 3-methylthio-substituted furans, pyrroles, thiophenes, and related derivatives.
Topics: Chromatography, High Pressure Liquid; Furans; Ketones; Mass Spectrometry; Methylation; Molecular Structure; Oxidation-Reduction; Pyrroles; Sulfhydryl Compounds; Thiophenes | 2008 |
Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon.
Topics: Aminoacylation; Anticodon; Base Pairing; Models, Chemical; Mutation; Nucleic Acid Conformation; Phosphoserine; Protein Biosynthesis; Protein Conformation; Pyrimidines; Pyrroles; RNA, Transfer, Amino Acyl; Serine-tRNA Ligase; Thiophenes | 2008 |
Pharmacophore mapping of a series of pyrrolopyrimidines, indolopyrimidines and their congeners as multidrug-resistance-associated protein (MRP1) modulators.
Topics: Computer Simulation; Humans; Hydrogen Bonding; Indoles; Inhibitory Concentration 50; Isoxazoles; Models, Molecular; Multidrug Resistance-Associated Proteins; Pyrimidines; Pyrroles; Quantitative Structure-Activity Relationship; Quinolones; Quinoxalines; Silymarin; Sulfonamides; Thiophenes | 2008 |
Amino(oligo)thiophene-based environmentally sensitive biomembrane chromophores.
Topics: Aldehydes; Amines; Carbocyanines; Fluorescent Dyes; Membrane Potentials; Optics and Photonics; Photons; Pyridinium Compounds; Pyrroles; Sensitivity and Specificity; Solvents; Spectrometry, Fluorescence; Thiophenes; Viscosity | 2008 |
Modulation of clopidogrel pharmacodynamic response.
Topics: Anticholesteremic Agents; Area Under Curve; Atorvastatin; Clopidogrel; Drug Interactions; Heptanoic Acids; Humans; Metabolic Clearance Rate; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Pyrroles; Thiophenes; Ticlopidine | 2008 |
The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine.
Topics: Aged; Animals; D-Amino-Acid Oxidase; Dizocilpine Maleate; Habituation, Psychophysiologic; Humans; Male; Models, Molecular; Pyrroles; Rats; Rats, Wistar; Recognition, Psychology; Schizophrenia; Serine; Thiophenes | 2009 |
Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues.
Topics: Antineoplastic Agents; Azepines; Checkpoint Kinase 1; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Electrons; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Neoplasms; Protein Kinases; Pyrroles; Structure-Activity Relationship; Thiophenes | 2009 |
Metal-free oxidative cross-coupling of unfunctionalized aromatic compounds.
Topics: Benzene Derivatives; Iodine; Naphthalenes; Onium Compounds; Oxidation-Reduction; Pyrroles; Thiophenes | 2009 |
Clean and direct synthesis of alpha,alpha'-bithiophenes and bipyrroles by metal-free oxidative coupling using recyclable hypervalent iodine(III) reagents.
Topics: Green Chemistry Technology; Iodine Compounds; Metals; Molecular Structure; Oxidation-Reduction; Pyrroles; Thiophenes | 2009 |
Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges.
Topics: Animals; Antipsychotic Agents; D-Amino-Acid Oxidase; Enzyme Activators; Genome, Human; Humans; Isoxazoles; Pyrazoles; Pyrroles; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Thiophenes | 2009 |
An extremely facile synthesis of furans, pyrroles, and thiophenes by the dehydrative cyclization of propargyl alcohols.
Topics: Alkynes; Catalysis; Cyclization; Furans; Propanols; Pyrroles; Thiophenes | 2009 |
Synthesis and evaluation of a thio analogue of duocarmycin SA.
Topics: Antineoplastic Agents, Alkylating; Duocarmycins; Indoles; Pyrroles; Sulfhydryl Compounds; Thiophenes | 2009 |
Hydrogenative desulphurization of thienopyrrolizinones: an easy and selective access to (Z)-phenethylidenepyrrolizinones with in vitro cytotoxic activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; KB Cells; Molecular Structure; Pyrroles; Structure-Activity Relationship; Sulfur; Thiopental; Thiophenes | 2010 |
Unexplained high fever in an elderly patient treated with clonidine, duloxetine, and atorvastatin.
Topics: Aged; Antidepressive Agents; Antihypertensive Agents; Atorvastatin; Body Temperature; Clonidine; Drug Interactions; Duloxetine Hydrochloride; Female; Fever of Unknown Origin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Polypharmacy; Pyrroles; Thiophenes; Time Factors | 2009 |
Orthogonal synthesis of densely functionalized pyrroles and thiophenes from the reactions of imidazo[1,5-a]pyridine carbene-derived zwitterions with electron-deficient alkynes.
Topics: Alkynes; Cyclization; Electrons; Magnetic Resonance Spectroscopy; Methane; Models, Molecular; Molecular Structure; Pyridines; Pyrroles; Stereoisomerism; Thiophenes | 2010 |
Effects of perfluorination on thiophene and pyrrole oligomers.
Topics: Models, Chemical; Pyrroles; Quantum Theory; Thiophenes | 2010 |
Looking for heteroaromatic rings and related isomers as interstellar candidates.
Topics: Furans; Isomerism; Prebiotics; Pyrroles; Thermodynamics; Thiophenes | 2010 |
Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands.
Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Line; Drug Antagonism; Drug Inverse Agonism; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Ligands; Pyrroles; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship; Thiophenes | 2010 |
Fibers with polypyrrole and polythiophene phases for isolation and determination of adrenolytic drugs from human plasma by SPME-HPLC.
Topics: Adrenergic Antagonists; Calibration; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Linear Models; Polymers; Propanolamines; Pyrroles; Reproducibility of Results; Solid Phase Microextraction; Thiophenes | 2010 |
New coated SPME fibers for extraction and fast HPLC determination of selected drugs in human blood.
Topics: Acetamides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Daptomycin; Humans; Linezolid; Oxazolidinones; Polymers; Pyrroles; Solid Phase Microextraction; Thiophenes | 2010 |
Synthesis and characterization of a iodine-125-labeled pyrrolo[1,2-a]thieno[3,2-e]pyrazine and evaluation as a potential 5-HT4R SPECT tracer.
Topics: Chromatography, High Pressure Liquid; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Pyrazines; Pyrroles; Thiophenes; Tomography, Emission-Computed, Single-Photon | 2010 |
Interpretation of vicinal proton-proton coupling constants of heteroaromatic molecules in terms of topological electron density descriptors.
Topics: Computer Simulation; Furans; Heterocyclic Compounds; Hydrocarbons, Aromatic; Magnetic Resonance Spectroscopy; Molecular Structure; Protons; Pyrroles; Quantum Theory; Reference Standards; Stereoisomerism; Thiophenes | 2010 |
Electronic structure calculations on helical conducting polymers.
Topics: Computer Simulation; Electric Conductivity; Electrons; Furans; Models, Molecular; Molecular Conformation; Polymers; Pyrroles; Thiophenes | 2010 |
Reactivity-based toxicity modelling of five-membered heterocyclic compounds: application to Tetrahymena pyriformis.
Topics: Furans; Glutathione; Heterocyclic Compounds; Models, Biological; Models, Chemical; Pyrroles; Quantitative Structure-Activity Relationship; Tetrahymena pyriformis; Thiophenes; Toxicity Tests; Water Pollutants, Chemical | 2010 |
The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Furans; Humans; Inhibitory Concentration 50; Nucleic Acid Conformation; Pyrroles; Thiophenes | 2011 |
High-level ab initio predictions for the ionization energies and heats of formation of five-membered-ring molecules: thiophene, furan, pyrrole, 1,3-cyclopentadiene, and borole, C4H4X/C4H4X+ (X = S, O, NH, CH2, and BH).
Topics: Cations; Computational Biology; Cyclopentanes; Electrons; Energy Transfer; Furans; Hot Temperature; Hydrogen; Models, Molecular; Molecular Structure; Pyrroles; Quantum Theory; Thermodynamics; Thiophenes; Vibration | 2011 |
A naphthodithiophene-diketopyrrolopyrrole donor molecule for efficient solution-processed solar cells.
Topics: Electric Power Supplies; Naphthalenes; Pyrroles; Solar Energy; Thiophenes | 2011 |
A novel approach to the rapid determination of amoxicillin in human plasma by solid phase microextraction and liquid chromatography.
Topics: Amoxicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Humans; Polymers; Pyrroles; Solid Phase Microextraction; Thiophenes | 2011 |
Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib.
Topics: Atorvastatin; Benzylamines; beta-Cyclodextrins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholesterol; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Female; Gefitinib; Heptanoic Acids; Humans; Lovastatin; Membrane Microdomains; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Pyrroles; Quinazolines; Thiophenes | 2011 |
DNA detection using functionalized conducting polymers.
Topics: Biosensing Techniques; Biotin; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; DNA; Electric Conductivity; Electrochemistry; Oligodeoxyribonucleotides; Optical Phenomena; Polymers; Pyrroles; Silanes; Spectrometry, Fluorescence; Thiophenes | 2011 |
Molecular electrostatic potential for exploring π-conjugation: a density-functional investigation.
Topics: Acetylene; Benzene; Ethylenes; Furans; Pyrroles; Quantum Theory; Static Electricity; Thiophenes | 2011 |
Molecular packing of high-mobility diketo pyrrolo-pyrrole polymer semiconductors with branched alkyl side chains.
Topics: Molecular Structure; Particle Size; Polymers; Pyrroles; Semiconductors; Stereoisomerism; Surface Properties; Thiophenes | 2011 |
A new way of solid-phase microextraction fibers preparation for selected antibiotic drug determination by HPLC-MS.
Topics: Acetamides; Anti-Infective Agents; Chromatography, High Pressure Liquid; Humans; Linear Models; Linezolid; Mass Spectrometry; Models, Chemical; Oxazolidinones; Ozone; Polymers; Pyrroles; Reproducibility of Results; Solid Phase Microextraction; Thiophenes | 2011 |
Redox-active Fe(CN)(6)(4-)-doped conducting polymers with greatly enhanced capacity as cathode materials for Li-ion batteries.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Electric Power Supplies; Electrodes; Ferrocyanides; Ions; Lithium; Oxidation-Reduction; Polymers; Pyrroles; Thiophenes | 2011 |
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Caspase 3; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Furans; Humans; In Vitro Techniques; Indoles; Injections, Intravenous; Male; Mice; Mice, Nude; Microsomes, Liver; Pyrroles; Solubility; Structure-Activity Relationship; Thiophenes; Tubulin Modulators | 2011 |
Excitation energy shuttling in oligothiophene-diketopyrrolopyrrole-fullerene triads.
Topics: Fullerenes; Molecular Structure; Pyrroles; Quantum Theory; Thiophenes | 2012 |
Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cobalt; HT29 Cells; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; MicroRNAs; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyrazines; Pyridazines; Pyrroles; Thiones; Thiophenes | 2012 |
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter
Topics: Alkynes; Animals; Antineoplastic Agents; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Drug Screening Assays, Antitumor; Folate Receptor 1; Humans; Proton-Coupled Folate Transporter; Purines; Pyrimidines; Pyrroles; Reduced Folate Carrier Protein; Stereoisomerism; Structure-Activity Relationship; Thiophenes | 2012 |
Binding affinity prediction for ligands and receptors forming tautomers and ionization species: inhibition of mitogen-activated protein kinase-activated protein kinase 2 (MK2).
Topics: Computer Simulation; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Intracellular Signaling Peptides and Proteins; Ions; Isomerism; Ligands; Models, Molecular; Protein Binding; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Quantitative Structure-Activity Relationship; Quantum Theory; Solutions; Thermodynamics; Thiophenes; Water | 2012 |
Polymer-based tubular microbots: role of composition and preparation.
Topics: Aniline Compounds; Bridged Bicyclo Compounds, Heterocyclic; Gold; Microscopy, Electron, Scanning; Microtechnology; Models, Biological; Nanotubes; Platinum; Polymerization; Polymers; Pyrroles; Robotics; Thiophenes | 2012 |
Development of novel molecularly imprinted solid-phase microextraction fibers and their application for the determination of antibiotic drugs in biological samples by SPME-LC/MS(n).
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Daptomycin; Humans; Linezolid; Mass Spectrometry; Molecular Imprinting; Oxazolidinones; Polymers; Pyrroles; Sensitivity and Specificity; Solid Phase Microextraction; Thiophenes | 2012 |
Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis.
Topics: Acute Disease; Alphavirus; Alphavirus Infections; Animals; Antiviral Agents; Brain; Cell Survival; Encephalitis, Viral; Indoles; Membranes, Artificial; Mice; Microsomes, Liver; Neurons; Permeability; Piperidines; Pyrroles; Replicon; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Viral Tropism; Virus Replication | 2012 |
Solution processed polymer tandem solar cell using efficient small and wide bandgap polymer:fullerene blends.
Topics: Electric Conductivity; Electric Power Supplies; Fullerenes; Polymers; Pyrroles; Solar Energy; Solutions; Thiophenes | 2012 |
New approaches to extraction techniques in determination of 4,4'-methylenebis(2-chloroaniline) in air and water solutions.
Topics: Air; Methylenebis(chloroaniline); Polymers; Pyrroles; Solid Phase Microextraction; Solutions; Solvents; Thiophenes; Water | 2012 |
The Suzuki reaction applied to the synthesis of novel pyrrolyl and thiophenyl indazoles.
Topics: Catalysis; Indazoles; Pyrroles; Thiophenes | 2012 |
Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs.
Topics: Cytidine; Fluorescent Dyes; Hydrogen Bonding; Molecular Structure; Pyrroles; Spectrum Analysis; Thiophenes | 2012 |
Highly π-extended copolymers with diketopyrrolopyrrole moieties for high-performance field-effect transistors.
Topics: Electron Transport; Polymers; Pyrroles; Thiophenes; Transistors, Electronic | 2012 |
Ambipolar behavior of hydrogen-bonded diketopyrrolopyrrole-thiophene co-oligomers formed from their soluble precursors.
Topics: Hydrogen Bonding; Molecular Structure; Pyrroles; Thiophenes | 2012 |
Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Drug Screening Assays, Antitumor; Extracellular Space; Female; Folic Acid Antagonists; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Proton-Coupled Folate Transporter; Pteroylpolyglutamic Acids; Pyrimidines; Pyrroles; Reduced Folate Carrier Protein; Structure-Activity Relationship; Tetrahydrofolates; Thiophenes; Tumor Microenvironment | 2012 |
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
Topics: Amidohydrolases; Analgesics; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Cyclohexanes; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Furans; Humans; Hyperalgesia; Maze Learning; Mice; Models, Molecular; Pain Threshold; Pyrroles; Rats; Recombinant Proteins; Stereotyped Behavior; Structure-Activity Relationship; Thiophenes | 2012 |
Histocompatibility and in vivo signal throughput for PEDOT, PEDOP, P3MT, and polycarbazole electrodes.
Topics: Animals; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Electrodes, Implanted; Electroencephalography; Materials Testing; Microglia; Polymers; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Processing, Computer-Assisted; Thiophenes | 2012 |
Heteroaromatic donors in donor-acceptor-donor based fluorophores facilitate zinc ion sensing and cell imaging.
Topics: Amines; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Ions; MCF-7 Cells; Microscopy, Fluorescence; Pyrroles; Quantum Theory; Spectrometry, Fluorescence; Thiophenes; Zinc | 2012 |
Coupling reactions of heteroarenes with phosphites under silver catalysis.
Topics: Azoles; Catalysis; Furans; Molecular Structure; Organophosphonates; Phosphites; Pyridines; Pyrroles; Silver; Thiophenes | 2012 |
Hypercrosslinked aromatic heterocyclic microporous polymers: a new class of highly selective CO2 capturing materials.
Topics: Adsorption; Aniline Compounds; Carbon Dioxide; Furans; Heterocyclic Compounds; Polymers; Porosity; Pyrroles; Surface Properties; Thiophenes | 2012 |
Computed NMR shielding of phosphorus-containing conjugated five-membered ring heterocycles as a measure of aromaticity.
Topics: Furans; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Phosphorus; Pyrroles; Thiophenes | 2012 |
Structural stabilization of DNA-templated nanostructures: crosslinking with 2,5-bis(2-thienyl)pyrrole monomers.
Topics: Circular Dichroism; DNA; Horseradish Peroxidase; Hydrogen Peroxide; Models, Molecular; Molecular Structure; Nanostructures; Oxidation-Reduction; Pyrroles; Spectrophotometry, Ultraviolet; Temperature; Thiophenes | 2013 |
A DFT study of pyrrole-isoxazole derivatives as chemosensors for fluoride anion.
Topics: Fluorescent Dyes; Fluorides; Isoxazoles; Models, Molecular; Pyrroles; Quantum Theory; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiophenes | 2012 |
Pyrrole versus quinoline formation in the palladium catalyzed reaction of 2-alkynyl-3-bromothiophenes and 2-alkynyl-3-bromofurans with anilines. A combined experimental and computational study.
Topics: Alkynes; Aniline Compounds; Bromine; Catalysis; Furans; Molecular Structure; Palladium; Pyrroles; Quantum Theory; Quinolines; Thiophenes | 2012 |
1-Heteroaromatic-substituted tetraphenylboroles: π-π interactions between aromatic and antiaromatic rings through a B-C bond.
Topics: Boron Compounds; Electrochemical Techniques; Furans; Models, Molecular; Molecular Structure; Pyrroles; Quantum Theory; Spectrophotometry, Ultraviolet; Thiophenes | 2012 |
Multifunctional conducting fibres with electrically controlled release of ciprofloxacin.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Delayed-Action Preparations; Electric Conductivity; Escherichia coli; Escherichia coli Infections; Humans; Polymers; Polystyrenes; Pyrroles; Streptococcal Infections; Streptococcus pyogenes; Thiophenes | 2013 |
Coculture with endothelial cells enhances osteogenic differentiation of periodontal ligament stem cells via cyclooxygenase-2/prostaglandin E2/vascular endothelial growth factor signaling under hypoxia.
Topics: Angiogenesis Inhibitors; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Endothelial Cells; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Nitrobenzenes; Osteogenesis; Periodontal Ligament; Prostaglandin Antagonists; Protein Kinase Inhibitors; Pyrroles; Signal Transduction; Stem Cells; Sulfonamides; Thiophenes; Triazoles; Vascular Endothelial Growth Factor A; Xanthones | 2013 |
Intramolecular excimer formation between 3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione chromophoric groups linked by a flexible alkyl spacer.
Topics: Models, Molecular; Molecular Structure; Pyrroles; Thiophenes | 2013 |
Low-energy electron scattering from the aza-derivatives of pyrrole, furan, and thiophene.
Topics: Electrons; Furans; Pyrroles; Thiophenes; Vibration | 2013 |
Chemical bonding and aromaticity in furan, pyrrole, and thiophene: a magnetic shielding study.
Topics: Furans; Magnetic Fields; Pyrroles; Quantum Theory; Thiophenes | 2013 |
Effect of substituents on the structure, stability, and π-dimerization of dithienylpyrrole radical cations.
Topics: Cations; Free Radicals; Molecular Structure; Pyrroles; Quantum Theory; Thiophenes | 2013 |
"Liquid-liquid-solid"-type superoleophobic surfaces to pattern polymeric semiconductors towards high-quality organic field-effect transistors.
Topics: Hydrophobic and Hydrophilic Interactions; Polymers; Pyrroles; Semiconductors; Sulfones; Thiophenes | 2013 |
The role of additive in diketopyrrolopyrrole-based small molecular bulk heterojunction solar cells.
Topics: Crystallization; Polystyrenes; Pyrroles; Solar Energy; Thiophenes; Tin Compounds | 2013 |
Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives.
Topics: Anti-Bacterial Agents; Antifungal Agents; Benzopyrans; Candida albicans; Dihydropyridines; Dose-Response Relationship, Drug; Escherichia coli; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Staphylococcus aureus; Structure-Activity Relationship; Thiazoles; Thiophenes | 2013 |
Computational atomistic blueprinting of novel conducting copolymers using particle swarm optimization.
Topics: Furans; Models, Molecular; Polymers; Pyrroles; Thiophenes | 2014 |
Rational design of organoboron derivatives as chemosensors for fluoride and cyanide anions and charge transport and luminescent materials for organic light-emitting diodes.
Topics: Anions; Boron Compounds; Cyanides; Electron Transport; Electronics; Fluorescence; Fluorides; Furans; Light; Models, Chemical; Models, Molecular; Molecular Structure; Pyrroles; Semiconductors; Thermodynamics; Thiophenes | 2014 |
Perfluoroalkyl-substituted thiophenes and pyrroles from donor-acceptor cyclopropanes and heterocumulenes: synthesis and exploration of their reactivity.
Topics: Cyclopropanes; Molecular Structure; Polyenes; Pyrroles; Stereoisomerism; Thiophenes | 2014 |
Exciton diffusion in disordered small molecules for organic photovoltaics: insights from first-principles simulations.
Topics: Diffusion; Electric Power Supplies; Electrons; Models, Molecular; Molecular Conformation; Pyrroles; Quantum Theory; Solar Energy; Temperature; Thiophenes | 2014 |
Polymerization of tellurophene derivatives by microwave-assisted palladium-catalyzed ipso-arylative polymerization.
Topics: Catalysis; Microwaves; Models, Molecular; Organoselenium Compounds; Palladium; Polymerization; Pyrroles; Solar Energy; Tellurium; Thiophenes | 2014 |
Ligand-free Pd-catalyzed C-N cross-coupling/cyclization strategy: an unprecedented access to 1-thienyl pyrroloquinoxalines for the new approach towards apoptosis.
Topics: Animals; Apoptosis; Catalysis; Cyclization; Dose-Response Relationship, Drug; Molecular Structure; Palladium; Phosphodiesterase 4 Inhibitors; Pyrroles; Quinoxalines; Structure-Activity Relationship; Thiophenes; Zebrafish | 2014 |
A non-fullerene electron acceptor based on fluorene and diketopyrrolopyrrole building blocks for solution-processable organic solar cells with an impressive open-circuit voltage.
Topics: Electric Power Supplies; Electrons; Fluorenes; Pyrroles; Quantum Theory; Solar Energy; Spectrophotometry, Ultraviolet; Thiophenes | 2014 |
Synthesis of cyclopentenes, pyrroles, and thiophenes via a sequence of propargyl-allenyl isomerizations, michael additions, and intramolecular Wittig reactions.
Topics: Catalysis; Cyclization; Cyclopentanes; Isomerism; Molecular Structure; Pargyline; Pyrroles; Stereoisomerism; Thiophenes | 2014 |
Optical, electrochemical, and magnetic properties of pyrrole- and thiophene-bridged 5,15-diazaporphyrin dimers.
Topics: Electrochemistry; Magnetics; Models, Molecular; Pyrroles; Thiophenes | 2015 |
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons.
Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Ileum; Male; Neurons, Afferent; Nodose Ganglion; Ondansetron; Patch-Clamp Techniques; Prostaglandins; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Sensory Receptor Cells; Serotonin; Signal Transduction; Stomach; Thiophenes; Triazoles; Visceral Afferents; Xanthones | 2015 |
Investigation of anion-π interactions involving thiophene walls incorporated calix[4]pyrroles.
Topics: Anions; Calixarenes; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Porphyrins; Pyrroles; Stereoisomerism; Thiophenes | 2015 |
Ferrocene-functionalized 4-(2,5-Di(thiophen-2-yl)-1H-pyrrol-1-yl)aniline: a novel design in conducting polymer-based electrochemical biosensors.
Topics: Aniline Compounds; Aspergillus niger; Biosensing Techniques; Calibration; Electric Conductivity; Electrochemistry; Enzymes, Immobilized; Equipment Design; Ferrous Compounds; Glucose; Hydrogen-Ion Concentration; Metallocenes; Polymerization; Polymers; Proton Magnetic Resonance Spectroscopy; Pyrroles; Spectrometry, Fluorescence; Thiophenes; Tin Compounds | 2015 |
Design and Biological Evaluation of Furan/Pyrrole/Thiophene-2-carboxamide Derivatives as Efficient DNA GyraseB Inhibitors of Staphylococcus aureus.
Topics: Animals; DNA Gyrase; Furans; Humans; Models, Molecular; Pyrroles; Staphylococcal Infections; Staphylococcus aureus; Thiophenes; Topoisomerase II Inhibitors; Zebrafish | 2015 |
Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane.
Topics: Catalysis; Furans; Organotin Compounds; Palladium; Pyrroles; Thiophenes | 2015 |
Eco-friendly solvents for palladium-catalyzed desulfitative C-H bond arylation of heteroarenes.
Topics: Benzofurans; Catalysis; Diethyl Pyrocarbonate; Ethers; Indoles; Palladium; Pyrroles; Solvents; Sulfones; Thiophenes | 2015 |
Palladium-catalyzed C-H ethoxycarbonyldifluoromethylation of electron-rich heteroarenes.
Topics: Catalysis; Electrons; Furans; Indoles; Methylation; Molecular Structure; Palladium; Pyrroles; Stereoisomerism; Thiophenes | 2015 |
An examination of the cardiac actions of PD117,302, a κ-opioid receptor agonist.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding, Competitive; Cardiac Pacing, Artificial; Cerebellum; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart Conduction System; Heart Rate; Heart Ventricles; Isolated Heart Preparation; Ligands; Male; Mice, Inbred BALB C; Myocardial Contraction; Pain; Pain Threshold; Potassium Channel Blockers; Potassium Channels; Protein Binding; Pyrroles; Radioligand Assay; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sodium Channel Blockers; Sodium Channels; Thiophenes; Ventricular Function, Left; Ventricular Pressure | 2015 |
How Many Biochemistries Are Available To Build a Cell?
Topics: Bacterial Proteins; Escherichia coli; Genetic Code; Genetic Engineering; Pyrroles; Thiophenes; Tryptophan | 2015 |
6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; CHO Cells; Cricetulus; Crystallography, X-Ray; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Folate Receptor 1; Folic Acid Antagonists; Heterografts; Humans; Mice, SCID; Models, Molecular; Neoplasm Transplantation; Pemetrexed; Phosphoribosylglycinamide Formyltransferase; Proton-Coupled Folate Transporter; Pyrimidines; Pyrroles; Stereoisomerism; Structure-Activity Relationship; Thiophenes | 2015 |
Monoamine oxidase inhibitory activities of heterocyclic chalcones.
Topics: Antiparkinson Agents; Chalcones; HeLa Cells; Humans; Hydrocarbons, Fluorinated; Kinetics; Kynuramine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrroles; Structure-Activity Relationship; Thiophenes | 2015 |
From indole to pyrrole, furan, thiophene and pyridine: Search for novel small molecule inhibitors of bacterial transcription initiation complex formation.
Topics: Anti-Bacterial Agents; Bacillus subtilis; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Escherichia coli; Furans; Indoles; Microbial Sensitivity Tests; Molecular Structure; Multiprotein Complexes; Protein Binding; Pyridines; Pyrroles; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes; Transcription Initiation, Genetic | 2016 |
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Topics: Bacterial Proteins; Benzoates; Carboxylic Acids; Crystallography, X-Ray; Drug Discovery; Fluorometry; Pseudomonas aeruginosa; Pyocyanine; Pyridines; Pyrroles; Quinolones; Quorum Sensing; Thiolester Hydrolases; Thiophenes; Virulence; Virulence Factors | 2016 |
Thieno[3,4-c]Pyrrole-4,6-Dione and Dithiophene-Based Conjugated Polymer for Organic Field Effect Transistors: High Mobility Induced by Synergic Effect of H-Bond and Vinyl Linkage.
Topics: Electrochemical Techniques; Hydrogen Bonding; Pyrroles; Quantum Theory; Temperature; Thermodynamics; Thiophenes; Transistors, Electronic; Vinyl Compounds | 2016 |
Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality.
Topics: Drug Design; HEK293 Cells; Humans; Ligands; Protein Binding; Pyrroles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Substrate Specificity; Thiophenes | 2016 |
Solution Processed Organic Photovoltaic Cells Using D-A-D-A-D Type Small Molecular Donor Materials with Benzodithiophene and Diketopyrrolopyrrole Units.
Topics: Ketones; Microscopy, Atomic Force; Proton Magnetic Resonance Spectroscopy; Pyrroles; Thiophenes | 2016 |
Novel benzothiophene 1,1-dioxide deoxygenation path for the microwave-assisted synthesis of substituted benzothiophene-fused pyrrole derivatives.
Topics: Chemistry Techniques, Synthetic; Microwaves; Models, Molecular; Molecular Conformation; Oxygen; Pyrroles; Thiophenes | 2017 |
Synthesis, characterization and biological studies of Schiff bases derived from heterocyclic moiety.
Topics: Aldehydes; Aminophenols; Anti-Bacterial Agents; Antioxidants; Bacteria; Bacterial Infections; Cresols; Crystallography, X-Ray; Drug Discovery; Humans; Microbial Sensitivity Tests; Models, Molecular; Nitrophenols; Pyrroles; Schiff Bases; Thiophenes | 2017 |
Construction of ferrocene modified conducting polymer based amperometric urea biosensor.
Topics: Aniline Compounds; Biosensing Techniques; Electric Conductivity; Electrochemical Techniques; Enzymes, Immobilized; Ferrous Compounds; Humans; Metallocenes; Polymers; Pyrroles; Thiophenes; Urea; Urease | 2017 |
New immobilisation method for oligonucleotides on electrodes enables highly-sensitive, electrochemical label-free gene sensing.
Topics: Biosensing Techniques; Carboxylic Acids; DNA; Electrochemical Techniques; Electrodes; Electroplating; Oligonucleotide Probes; Pyrroles; Thiophenes | 2017 |
Highly absorbing multispectral near-infrared polymer nanoparticles from one conjugated backbone for photoacoustic imaging and photothermal therapy.
Topics: Animals; Female; HeLa Cells; Humans; Hyperthermia, Induced; Infrared Rays; Ketones; MCF-7 Cells; Mice, Inbred ICR; Nanoparticles; Neoplasms; Optical Imaging; Photoacoustic Techniques; Phototherapy; Pyrroles; Theranostic Nanomedicine; Thiophenes | 2017 |
Novel ATP-competitive Akt inhibitor afuresertib suppresses the proliferation of malignant pleural mesothelioma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzylamines; Caspase 3; Caspase 7; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Forkhead Box Protein O1; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Inhibitory Concentration 50; Mesothelioma; Oxadiazoles; Phosphorylation; Phosphorylcholine; Pleural Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Quinoxalines; Sulfonamides; Thiadiazoles; Thiophenes | 2017 |
pH Switchable Nanoassembly for Imaging a Broad Range of Malignant Tumors.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Screening Assays, Antitumor; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Ketones; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Neoplasms, Experimental; Pyrroles; Thiophenes; Tumor Microenvironment | 2017 |
Discovery of Rogaratinib (BAY 1163877): a pan-FGFR Inhibitor.
Topics: Drug Discovery; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Small Molecule Libraries; Thiophenes | 2018 |
Design and synthesis of estrogen receptor ligands with a 4-heterocycle-4-phenylheptane skeleton.
Topics: Dose-Response Relationship, Drug; Drug Design; Estrogen Receptor Antagonists; Heptanes; Humans; Indoles; Ligands; MCF-7 Cells; Models, Molecular; Molecular Structure; Pyrroles; Receptors, Estrogen; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured | 2018 |
Determination of a PDE4 inhibitor Hemay005 in human plasma and urine by UPLC-MS/MS and its application to a PK study.
Topics: Acetamides; Analytic Sample Preparation Methods; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Phosphodiesterase 4 Inhibitors; Pyrroles; Reproducibility of Results; Tandem Mass Spectrometry; Thiophenes; Urinalysis | 2018 |
An Asymmetric Furan/Thieno[3,2-b]Thiophene Diketopyrrolopyrrole Building Block for Annealing-Free Green-Solvent Processable Organic Thin-Film Transistors.
Topics: Furans; Molecular Structure; Polymers; Pyrroles; Solvents; Thiophenes; Transistors, Electronic | 2018 |
Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker.
Topics: Action Potentials; Administration, Intravenous; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; Humans; Injections, Intradermal; Isolated Heart Preparation; Male; Mice; Myocytes, Cardiac; Neural Conduction; Pain Threshold; Papio; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Thiophenes; Time Factors; Xenopus laevis | 2018 |
Tofacitinib and TPCA-1 exert chondroprotective effects on extracellular matrix turnover in bovine articular cartilage ex vivo.
Topics: Amides; Animals; Cartilage, Articular; Cattle; Chondrocytes; Collagen Type II; Extracellular Matrix Proteins; Imidazoles; Osteoarthritis; Oxazines; Piperidines; Proteoglycans; Pyridines; Pyrimidines; Pyrroles; Thiophenes | 2019 |
Synthesis and Characterization of Bis[1]benzothieno[3,2-b:2',3'-d]pyrroles: Quantitative Effects of Benzannulation on Dithieno[3,2-b:2',3'-d]pyrroles.
Topics: Molecular Structure; Pyrroles; Thiophenes | 2018 |
Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Phosphorylation; Piperazines; Pyrroles; Random Allocation; Rats; Receptors, Fibroblast Growth Factor; Thiophenes; Xenograft Model Antitumor Assays | 2019 |
Synthesis, characterization, anticancer evaluation and mechanisms of cytotoxic activity of novel 3-hydroxy-3-pyrrolin-2-ones bearing thenoyl fragment: DNA, BSA interactions and molecular docking study.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Death; Cell Proliferation; Cells, Cultured; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Docking Simulation; Molecular Structure; Pyrroles; Serum Albumin, Bovine; Structure-Activity Relationship; Thiophenes; Viscosity | 2019 |
A new screening tool for FGFR inhibitor treatment?
Topics: Early Detection of Cancer; Humans; Neoplasms; Piperazines; Pyrroles; RNA, Messenger; Thiophenes | 2019 |
Radical addition polymerization: Enzymatic template-free synthesis of conjugated polymers and their nanostructure fabrication.
Topics: Aniline Compounds; Biocatalysis; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Nanostructures; Polymerization; Pyrroles; Thiophenes | 2019 |
Fused Bithiophene Imide Oligomer and Diketopyrrolopyrrole Copolymers for n-Type Thin-Film Transistors.
Topics: Density Functional Theory; Imides; Ketones; Molecular Structure; Polymers; Pyrroles; Semiconductors; Thiophenes; Transistors, Electronic | 2019 |
Enhanced electrochemical sensing performance by insitu electrocopolymerization of pyrrole and thiophene-grafted chitosan.
Topics: Biosensing Techniques; Chitosan; Electrochemical Techniques; Electrodes; Membranes, Artificial; Pyrroles; Thiophenes | 2020 |
Thieno[3,2-b]thiophene-DPP based near-infrared nanotheranostic agent for dual imaging-guided photothermal/photodynamic synergistic therapy.
Topics: Animals; Female; HeLa Cells; Humans; Infrared Rays; Ketones; Mice; Mice, Nude; Optical Imaging; Photochemotherapy; Pyrroles; Singlet Oxygen; Theranostic Nanomedicine; Thiophenes | 2019 |
Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties.
Topics: Amides; Animals; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; K562 Cells; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Docking Simulation; Molecular Structure; Neoplasms, Experimental; Pyrroles; Structure-Activity Relationship; Thiophenes | 2020 |
Absolute Chiral Recognition with Hybrid Wireless Electrochemical Actuators.
Topics: Electric Conductivity; Electrochemical Techniques; Molecular Conformation; Polymers; Pyrroles; Thiophenes | 2020 |
A novel polymer coated magnetic porous carbon nanocomposite derived from a metal-organic framework for multi-target environmental pollutants preconcentration.
Topics: Carbon; Environmental Monitoring; Environmental Pollutants; Limit of Detection; Magnetics; Metal-Organic Frameworks; Nanocomposites; Polymers; Porosity; Pyrroles; Thiophenes | 2020 |
Ceritinib increases sensitivity of AKT inhibitors to gastric cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Glycogen Synthase Kinase 3 beta; Humans; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; Stomach Neoplasms; Sulfones; Thiophenes; Tumor Burden; Xenograft Model Antitumor Assays | 2021 |
FGFR alterations in urothelial carcinoma: Picking the right target.
Topics: Carcinoma, Transitional Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Gene Fusion; Humans; Molecular Targeted Therapy; Morpholines; Mutation; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Thiophenes; Urinary Bladder Neoplasms | 2021 |
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Nuclear Receptor Subfamily 1, Group F, Member 1; Paracrine Communication; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Ribonucleosides; Signal Transduction; Sulfonamides; Thiophenes; Wortmannin | 2021 |
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; Lactones; Myeloid Cell Leukemia Sequence 1 Protein; Proteasome Inhibitors; Pyrimidines; Pyrroles; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Spheroids, Cellular; Thiophenes; Time Factors | 2021 |
Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers.
Topics: Animals; Cattle; Dihydroxyphenylalanine; Enzymes, Immobilized; Equipment Design; Motion; Oligopeptides; Oxidoreductases Acting on CH-CH Group Donors; Polymers; Pyrroles; Stereoisomerism; Technology; Thiophenes | 2021 |
Cilostazol-imprinted polymer film-coated electrode as an electrochemical chemosensor for selective determination of cilostazol and its active primary metabolite.
Topics: Carbazoles; Cilostazol; Electrodes; Humans; Molecular Imprinting; Molecularly Imprinted Polymers; Polymers; Pyrroles; Thiophenes | 2022 |
Electroconductive Polythiophene Nanocomposite Fibrous Scaffolds for Enhanced Osteogenic Differentiation via Electrical Stimulation.
Topics: Animals; Cell Proliferation; Electric Stimulation; Mice; Nanocomposites; Osteogenesis; Polymers; Pyrroles; Thiophenes; Tissue Scaffolds | 2022 |
Using diketopyrrolopyrroles to stabilize double excitation and control internal conversion.
Topics: Ketones; Luminescence; Pyrroles; Thiophenes | 2022 |
Heterocyclization of Bis(2-chloroprop-2-en-1-yl)sulfide in Hydrazine Hydrate-KOH: Synthesis of Thiophene and Pyrrole Derivatives.
Topics: Alkalies; Hydrazones; Pyrroles; Sulfides; Sulfur; Thiophenes | 2022 |
Building Block Engineering toward Realizing High-Performance Electrochromic Materials and Glucose Biosensing Platform.
Topics: Glucose; Polymerization; Polymers; Pyrroles; Thiophenes | 2023 |