pyrroles has been researched along with tetradecanoylphorbol acetate in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.35) | 18.7374 |
| 1990's | 19 (25.68) | 18.2507 |
| 2000's | 40 (54.05) | 29.6817 |
| 2010's | 14 (18.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gray, LS; Haverstick, DM | 1 |
| Bentsman, G; McKinley, G; Potash, MJ; Volsky, DJ | 1 |
| Fukuzaki, H; Shuntoh, H; Tanaka, C; Taniyama, K | 1 |
| Pratt, MM; Salathe, M; Wanner, A | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Bell, LL; Cheung, JY; Lynch, CJ; Miller, BA | 1 |
| Fujiwara, R; Miyabo, S; Nakai, T; Shimada, A; Tamai, T | 1 |
| Audesirk, G; Cabell, L | 1 |
| Guatelli, J; Kraus, G; Luznik, L; Richman, D; Wong-Staal, F | 1 |
| Lee, JC; White, JR | 1 |
| Bonev, AD; Nelson, MT | 1 |
| Bengis-Garber, C; Gruener, N | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Davis, FB; Davis, PJ; Lin, HY; Thacorf, HR | 1 |
| Hruska, K; Onishi, T | 1 |
| Cikós, T; Kalthoff, H; Krull, NB; Ungefroren, H | 1 |
| Bernstein, PR; Bonuccelli, CM; Cao, GL; Huang, YI; Meng, M; Pou, S; Rosen, GM; Salcedo, TW; Strimpler, A; Surichamorn, W; Veale, C | 1 |
| Huang, LJ; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Dessauer, CW; Hume, JR; Keef, KD; Zhong, J | 1 |
| Brown, EJ; Wang, J | 1 |
| Kataoka, K; Nakamura, Y; Si, Q | 1 |
| Chung, HT; Kim, SB; Lee, HS; Pae, HO; Seo, WG; Shin, M | 1 |
| Hoff, HF; Hoppe, G; O'Neil, J; Podrez, EA; Sayre, LM; Sheibani, N | 1 |
| Huang, HC; Nguyen, T; Pickett, CB | 1 |
| Eisenreichová, E; Haladová, M; Józová, B; Mucaji, P; Novotný, L; Vachálková, A | 1 |
| Gemba, M; Kohda, Y | 1 |
| Cook, DA; Nessim, MA; Vollrath, B; Wickman, G | 1 |
| Bonardo, B; Deprez-Beauclair, P; Juhan-Vague, I; Laouenan, H; Lopez, S; Nalbone, G; Peiretti, F | 1 |
| Hu, J; Krieger, C; Pelech, SL; Raymond, LA; Wagey, R | 1 |
| Hirata, H; Kamata, H; Kamata, K; Oka, S; Okamoto, S; Yagisawa, H | 1 |
| Huang, Y; Ishizawa, M; Ishizuka, T; Kajita, K; Kawai, Y; Kimura, M; Miura, A; Morita, H; Uno, Y; Yasuda, K | 1 |
| Larsson, C; Svensson, K; Trollér, U; Zeidman, R | 1 |
| Bruegel, M; Stein, O; Stein, Y; Teupser, D; Thiery, J | 1 |
| Curtis, JL; Hu, B; Polak, T; Punturieri, A; Sonstein, J; Todt, JC | 1 |
| Ellershaw, DC; Greenwood, IA; Large, WA | 1 |
| Bloem, LJ; Estridge, TB; Iversen, PW; McDonald, CE; Schrementi, JP; Vlahos, CJ; Wang, J; Wang, X; Yu, L; Zhang, Y | 1 |
| Lan, C; Vollrath, B; Wickman, G | 1 |
| Allione, A; Beltramo, E; Buttiglieri, S; D'Alù, F; Lacaria, A; Pomero, F; Ponte, E; Porta, M | 1 |
| Carlson, RR; Dudman, JT; Konradi, C; Macías, W | 1 |
| Coco, L; Dell'Era, P; Metra, M; Nicoli, S; Presta, M; Ronca, R | 1 |
| Cao, C; Choy, H; Freeman, ML; Morrow, JD; Saha, D; Sekhar, KR | 1 |
| Huang, SH; Shen, WJ; Wang, SM; Yeo, HL | 1 |
| Dang, L; Qu, X; Seale, JP | 1 |
| Diniz, C; Fresco, P; Gonçalves, J | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Boileau, C; Fahmi, H; Laufer, S; Lavigne, M; Martel-Pelletier, J; Pelletier, JP; Tardif, G | 1 |
| Gnegy, ME; Guptaroy, B; Johnson, LA; Lund, D; Shamban, S | 1 |
| Andrassy, M; Belov, D; Harja, E; Katus, HA; Leitges, M; Nawroth, PP; Schmidt, AM; Yan, SD; Yan, SF; Zou, YS | 1 |
| Alonso, MJ; Beltrán, A; Manso, AM; Pacheco, ME; Redondo, J; Salaices, M | 1 |
| Chen, YH; Tsai, MC | 1 |
| Golab, M; Skwarlo-Sonta, K | 1 |
| Das, AK; Dev, S; Fujimoto, K; Fukui, H; Horio, S; Kitamura, Y; Mishima, R; Mizuguchi, H; Takeda, N; Wakayama, Y; Yoshimura, S | 1 |
| Eggo, MC; Susarla, R; Watkinson, JC | 1 |
| Fleischmann, BK; Hescheler, J; Reppel, M; Reuter, H; Sasse, P; Schunkert, H | 1 |
| Hirata, H; Kamata, H; Kaneko, S; Kaneshiro, K; Kawauchi, K; Moriyama, Y; Okamoto, S; Tobiume, K; Ueda, E | 1 |
| Ishida, K; Iwanaga, T; Karakawa, T; Kitamado, M; Maruyama, K; Mitani, Y; Muramoto, Y; Nabeshima, T; Nakagawa, K; Sasamoto, K; Sato, K | 1 |
| Brown, AP; Corot, C; Gillard, JH; Graves, MJ; Lancelot, E; Müller, K; Patterson, AJ; Skepper, JN; Tang, TY; Thompson, PW | 1 |
| Hill, JS; Qiu, G | 1 |
| Akhmedov, A; Besler, C; Cosentino, F; Iliceto, S; Kouroedov, A; Lüscher, TF; Mocharla, P; Osto, E; Rohrer, L; Volpe, M; von Eckardstein, A | 1 |
| Akaike, A; Ito, R; Izumi, Y; Katsuki, H; Kume, T; Niidome, T; Sugimoto, H; Taguchi, R; Takada-Takatori, Y | 1 |
| Carluccio, MA; De Caterina, R; Distante, A; Massaro, M; Scoditti, E; Storelli, C; Zampolli, A | 1 |
| Budde, K; Kramer, S; Ladhoff, J; Lorkowski, C; Mashreghi, MF; Matz, M; Neumayer, HH; Weber, U | 1 |
| Chen, Z; Jin, H; Lei, Y; Luo, H; Su, C; Wang, T; Zhong, B; Zhuang, M; Zou, J | 1 |
| Belo, VA; Gerlach, RF; Guimaraes, DA; Izidoro-Toledo, TC; Tanus-Santos, JE | 1 |
| Dai, Y; Kobayashi, K; Kogure, Y; Noguchi, K; Wan, Y; Wang, S; Yamanaka, H; Zhang, W; Zhu, W | 1 |
| Cucinotta, M; Oteri, R; Teti, D; Venza, I; Venza, M; Visalli, M | 1 |
| Almami, I; Bonner, PL; Dickenson, JM; Hargreaves, AJ | 1 |
| Andritsos, L; Awan, FT; Blachly, JS; Byrd, JC; Cannon, M; Chen, CS; El-Gamal, D; Jones, J; LaFollette, TD; Lapalombella, R; Lehman, A; Maddocks, K; Williams, E; Williams, K; Woyach, JA; Wu, CH; Zhang, X; Zhong, Y | 1 |
| Abbas, K; Hardy, M; Karoui, H; Ouari, O; Peyrot, F; Poulhès, F; Tordo, P | 1 |
| Fujiwara, K; Fukuda, N; Hanazawa, S; Masuhiro, Y; Matsuda, H; Saito, K; Shinohara, K; Soma, M; Ueno, T | 1 |
| Du, ZY; Liu, WF; Liu, WT; Mou, XQ; Sheng, ZJ; Wang, SH; Xi, QM; Xu, XT; Zhang, K; Zhao, SQ; Zheng, X | 1 |
| Han, Y; Mesplède, T; Quan, Y; Wainberg, MA; Xu, H | 1 |
| Mitchell, TS; Moots, RJ; Wright, HL | 1 |
| Chamorro-Cevallos, GA; Cristobal-Luna, JM; Delgado, F; Escalante, CH; Esquivel-Campos, AL; Gómez-García, O; Gutiérrez-Rebolledo, GA; Hernández-Benitez, RI; Madrigal, DA; Pérez-Gutiérrez, S; Tamariz, J | 1 |
74 other study(ies) available for pyrroles and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. II. Interaction between phorbol ester- and cAMP-sensitive pathways.
Topics: Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Cell Aggregation; Cells, Cultured; Cyclic AMP; Humans; Indoles; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Lymphocyte Function-Associated Antigen-1; Lymphocytes; Protein Kinase C; Protein Kinases; Pyrroles; Tetradecanoylphorbol Acetate | 1992 |
A Tat antagonist inhibits HIV-1 induction in naturally infected and experimentally infected T cells.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Benzodiazepinones; Cell Line; Cloning, Molecular; DNA, Viral; Gene Products, tat; HIV Core Protein p24; HIV-1; Pyrroles; Rats; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate | 1992 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine | 1993 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.
Topics: Adult; Alkaloids; Analog-Digital Conversion; Biological Transport; Bucladesine; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Erythroid Precursor Cells; Erythropoietin; Genistein; Humans; Image Processing, Computer-Assisted; Indoles; Intercellular Signaling Peptides and Proteins; Intracellular Fluid; Isoflavones; Isoquinolines; Naphthalenes; Peptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Videotape Recording; Wasp Venoms | 1994 |
Effects of insulin, insulin-like growth factor-I, and phorbol esters on neutral cholesteryl esterase activity in cultured rat vascular smooth muscle cells.
Topics: Alkaloids; Animals; Aorta; Carbazoles; Cells, Cultured; Cyclic AMP; Indoles; Insulin; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; Phenylurea Compounds; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Staurosporine; Sterol Esterase; Sterol O-Acyltransferase; Tetradecanoylphorbol Acetate | 1995 |
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cells, Cultured; Dendrites; Female; Hippocampus; Imidazoles; Indoles; Isoquinolines; Naphthalenes; Neurites; Piperazines; Polycyclic Compounds; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Pyramidal Tracts; Pyrroles; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Tat-independent replication of human immunodeficiency viruses.
Topics: Benzodiazepines; Cell Line; Defective Viruses; Drug Antagonism; Gene Products, tat; HIV; HIV-1; HIV-2; Humans; Monocytes; Pyrroles; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha; Virus Replication | 1995 |
Effect of protein kinase inhibitors on IL-8/NAP-1 release from human umbilical vein endothelial cells.
Topics: Alkaloids; Benzoquinones; Carbazoles; Cells, Cultured; Endothelium, Vascular; Humans; Indoles; Interleukin-1; Interleukin-8; Lactams, Macrocyclic; Protein Kinase Inhibitors; Pyrroles; Quinones; Recombinant Proteins; Rifabutin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
Muscarinic inhibition of ATP-sensitive K+ channels by protein kinase C in urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Diglycerides; Glyburide; Guanosine Diphosphate; Guinea Pigs; In Vitro Techniques; Indoles; Maleimides; Membrane Potentials; Muscarinic Antagonists; Muscle, Smooth; Potassium Channels; Protein Kinase C; Pyrroles; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thionucleotides; Urinary Bladder | 1993 |
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: a possible pathway for inhibition of the respiratory burst.
Topics: Bucladesine; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphoproteins; Phosphorylation; Pyrroles; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Potentiation by thyroxine of interferon-gamma-induced antiviral state requires PKA and PKC activities.
Topics: Animals; Calmodulin; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; HeLa Cells; Humans; Indoles; Interferon-gamma; L Cells; Mice; Protein Kinase C; Pyrroles; Pyrrolidinones; Rhabdoviridae Infections; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thyroxine; Time Factors; Vesicular stomatitis Indiana virus; Viral Interference | 1996 |
Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; G1 Phase; Gene Expression; Indoles; Microtubule-Associated Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Pyrroles; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro.
Topics: Cell Survival; Cells, Cultured; Humans; Kinetics; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oligopeptides; Pyrroles; Serine Proteinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytosol; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Pyrroles; Quinolones; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 1999 |
Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Carbazoles; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Macrophage-1 Antigen; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyrroles; Receptors, IgG; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Differential regulation of microglial NO production by protein kinase C inhibitors.
Topics: Animals; Carbazoles; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Indoles; Isoquinolines; Lipopolysaccharides; Microglia; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Isoforms; Protein Kinase C; Pyrroles; Rats; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 2001 |
Protein kinase A or C modulates the apoptosis induced by lectin II isolated from Korean mistletoe, Viscum album var. Coloratum, in the human leukemic HL-60 cells.
Topics: Apoptosis; Bucladesine; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Indoles; Lectins; Mistletoe; Plant Lectins; Plant Preparations; Plant Proteins; Plants, Medicinal; Protein Kinase C; Pyrroles; Ribosome Inactivating Proteins, Type 2; Staurosporine; Tetradecanoylphorbol Acetate; Toxins, Biological | 2000 |
Macrophage receptors responsible for distinct recognition of low density lipoprotein containing pyrrole or pyridinium adducts: models of oxidized low density lipoprotein.
Topics: Animals; Antibodies, Monoclonal; CD36 Antigens; Cell Line; CHO Cells; Cricetinae; Female; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Monocytes; Pyridinium Compounds; Pyrroles; Receptors, Immunologic; Receptors, Scavenger; Scavenger Receptors, Class A; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2.
Topics: Animals; Antioxidants; beta-Naphthoflavone; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydroquinones; Indoles; Leucine Zippers; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Response Elements; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured | 2000 |
Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Ethanol; Liliaceae; Mice; Mutagens; Plant Extracts; Polarography; Pyrroles; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbazoles; Carcinogens; Cephaloridine; Cephalosporins; Cyclic AMP; Enzyme Inhibitors; Free Radicals; Gluconeogenesis; In Vitro Techniques; Indoles; Kidney Cortex; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; p-Aminohippuric Acid; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm.
Topics: Animals; Anti-Bacterial Agents; Bradykinin; Cells, Cultured; Cerebral Arteries; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Female; Gentamicins; Indoles; Isometric Contraction; Kanamycin; Male; Muscle, Smooth, Vascular; Neomycin; Peptides, Cyclic; Polyamines; Polyelectrolytes; Protein Kinase C; Pyrroles; Streptomycin; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasospasm, Intracranial | 2001 |
Effect of atorvastatin on plasminogen activator inhibitor type-1 synthesis in human monocytes/macrophages.
Topics: Atorvastatin; Heptanoic Acids; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Monocytes; Plasminogen Activator Inhibitor 1; Pyrroles; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2001 |
Modulation of NMDA-mediated excitotoxicity by protein kinase C.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Cell Fractionation; Cell Line; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Humans; Immunoblotting; Indoles; Isoenzymes; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Protein Subunits; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) alpha-induced transcriptional activation by NF-kappaB.
Topics: Apoptosis; Base Sequence; cdc42 GTP-Binding Protein; Genes, Reporter; HeLa Cells; Humans; I-kappa B Kinase; Indoles; Luciferases; MAP Kinase Kinase Kinase 1; NF-kappa B; Plasmids; Protein Serine-Threonine Kinases; Pyrroles; rac1 GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2001 |
Differential effect of PKC isoform on insulin- and phorbol ester-stimulated glucose uptake mechanism in rat adipocytes.
Topics: Adipocytes; Androstadienes; Animals; Biological Transport, Active; Deoxyglucose; Enzyme Activation; Enzyme Inhibitors; Glucose; In Vitro Techniques; Indoles; Insulin; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells.
Topics: Cell Differentiation; Culture Media, Serum-Free; Enzyme Inhibitors; Flavonoids; GAP-43 Protein; Gene Expression Regulation; Genes, Reporter; Isoenzymes; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurites; Neuroblastoma; Neurons; Neuropeptide Y; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
HMG-CoA reductase inhibitors reduce adhesion of human monocytes to endothelial cells.
Topics: Anticholesteremic Agents; Atorvastatin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lipopolysaccharide Receptors; Monocytes; NF-kappa B; Pyridines; Pyrroles; Receptors, LDL; RNA, Messenger; Simvastatin; Tetradecanoylphorbol Acetate; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2001 |
Activation of protein kinase C beta II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages.
Topics: Acetophenones; Animals; Apoptosis; Benzopyrans; Blotting, Western; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Female; Flow Cytometry; Immunoblotting; Indoles; Inhibitory Concentration 50; Isoenzymes; Liposomes; Macrophages; Mice; Mice, Inbred C57BL; Myristic Acid; Phagocytosis; Protein Isoforms; Protein Kinase C; Protein Kinase C beta; Protein Transport; Pyrroles; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors | 2002 |
Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Carbazoles; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Membrane Potentials; Muscle, Smooth, Vascular; Naphthalenes; Norepinephrine; Phenanthridines; Portal Vein; Prazosin; Propranolol; Pyrroles; Pyrrolidinones; Rabbits; Tetradecanoylphorbol Acetate | 2002 |
Protein kinase C betaII activation induces angiotensin converting enzyme expression in neonatal rat cardiomyocytes.
Topics: Angiotensin I; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Isoenzymes; Mesylates; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transduction, Genetic | 2003 |
Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Basilar Artery; Benzamides; Biological Transport; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Muscle, Smooth, Vascular; Oxyhemoglobins; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rabbits; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstriction | 2003 |
Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes.
Topics: Animals; Apoptosis; Cattle; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Flow Cytometry; Glucose; Isoenzymes; Mesylates; Pericytes; Protein Kinase C; Pyrroles; Retina; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2003 |
Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; Embryo, Mammalian; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoquinolines; Neurons; Nifedipine; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 2003 |
Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development.
Topics: Animals; Butadienes; Cell Differentiation; Cell Size; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Mesoderm; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Myosin Heavy Chains; Nitriles; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Xenopus Proteins | 2003 |
The antiangiogenic agent SU5416 down-regulates phorbol ester-mediated induction of cyclooxygenase 2 expression by inhibiting nicotinamide adenine dinucleotide phosphate oxidase activity.
Topics: Angiogenesis Inhibitors; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Down-Regulation; Drug Interactions; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Indoles; Isoenzymes; Lung Neoplasms; Membrane Proteins; NADPH Oxidases; Prostaglandin-Endoperoxide Synthases; Pyrroles; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Animals; Benzylamines; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Glycerol; Hydroxycholesterols; Indoles; Lignans; Lipolysis; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naphthalenes; Oleic Acid; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles | 2004 |
Reduction of high glucose and phorbol-myristate-acetate-induced endothelial cell permeability by protein kinase C inhibitors LY379196 and hypocrellin A.
Topics: Biological Transport; Cell Membrane Permeability; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; Glucose; Humans; Isoenzymes; Mesylates; Perylene; Phenol; Protein Kinase C; Pyrroles; Quinones; Tetradecanoylphorbol Acetate | 2004 |
Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Arteries; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Indoles; Isoquinolines; Male; Norepinephrine; Phenethylamines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptor, Adenosine A2A; Signal Transduction; Sulfonamides; Tail; Tetradecanoylphorbol Acetate; Triazoles; Tritium; Type C Phospholipases | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
Topics: Acetates; Aged; Cells, Cultured; Chondrocytes; Collagenases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Interleukin-1; Lipoxygenase Inhibitors; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Middle Aged; Osteoarthritis, Knee; Promoter Regions, Genetic; Pyrroles; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2005 |
Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta.
Topics: Amphetamine; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Nerve Tissue Proteins; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2005 |
Central role of PKCbeta in neointimal expansion triggered by acute arterial injury.
Topics: Animals; Aorta; Blood Glucose; Cell Division; Cell Movement; Cells, Cultured; Constriction, Pathologic; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Femoral Artery; Flavonoids; Humans; Immediate-Early Proteins; Indoles; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Maleimides; Mesylates; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Peroxidase; Protein Kinase C; Protein Kinase C beta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Tunica Intima | 2005 |
High glucose enhances inducible nitric oxide synthase expression. Role of protein kinase C-betaII.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Interleukin-1; Male; Mesylates; Muscle, Smooth, Vascular; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 2006 |
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron.
Topics: Action Potentials; Alkaloids; Animals; Benzophenanthridines; Calcium; Carbazoles; Electrophysiology; Enzyme Inhibitors; Estrenes; Ganglia, Invertebrate; Hallucinogens; In Vitro Techniques; Indoles; Isoquinolines; Magnesium; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrroles; Pyrrolidinones; Snails; Sulfonamides; Tetradecanoylphorbol Acetate | 2007 |
Mechanisms involved in the anti-inflammatory action of inhaled tea tree oil in mice.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Cell Count; Cyclooxygenase Inhibitors; Hypothalamo-Hypophyseal System; Immunologic Factors; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Biological; Peritoneal Cavity; Pituitary-Adrenal System; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Pyrroles; Reactive Oxygen Species; Receptors, Corticotropin-Releasing Hormone; Tea Tree Oil; Tetradecanoylphorbol Acetate; Thiophenes; Zymosan | 2007 |
Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cyclic GMP; Enzyme Inhibitors; HeLa Cells; Histamine; Histamine H1 Antagonists; Humans; Indoles; Luciferases; Protein Kinase C; Pyrilamine; Pyrroles; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Transfection; Tritium; Up-Regulation | 2007 |
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2007 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fetal Development; Gestational Age; Heart; Heart Ventricles; Indoles; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Pyrroles; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2007 |
Suppression of AP-1 activity by cycloprodigiosin hydrochloride.
Topics: Biotransformation; Blotting, Western; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; Genes, Reporter; HeLa Cells; Humans; Immunosuppressive Agents; Indoles; JNK Mitogen-Activated Protein Kinases; Luciferases; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Plasmids; Pyrroles; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2007 |
Applicability of new spin trap agent, 2-diphenylphosphinoyl-2-methyl-3,4-dihydro-2H-pyrrole N-oxide, in biological system.
Topics: Cell Line; Cell-Free System; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Neutrophils; Pyrroles; Spin Labels; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase | 2008 |
Atorvastatin and uptake of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) in human monocyte-macrophages: implications for magnetic resonance imaging.
Topics: Atorvastatin; Cells, Cultured; Contrast Media; Dextrans; Dose-Response Relationship, Drug; Ferrosoferric Oxide; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Iron; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Nanoparticles; Oxides; Particle Size; Pyrroles; Tetradecanoylphorbol Acetate | 2008 |
Atorvastatin inhibits ABCA1 expression and cholesterol efflux in THP-1 macrophages by an LXR-dependent pathway.
Topics: Atorvastatin; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Foam Cells; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Liver X Receptors; Macrophage Activation; Macrophages; Orphan Nuclear Receptors; Pyrroles; Receptors, Cytoplasmic and Nuclear; rhoA GTP-Binding Protein; RNA, Messenger; Tetradecanoylphorbol Acetate | 2008 |
Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atherosclerosis; Carcinogens; Cell Line; Foam Cells; Gene Expression Regulation; Humans; Immunity, Innate; Lipopolysaccharide Receptors; Lipopolysaccharides; Lipoproteins, LDL; Macrophage Activation; Mesylates; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Small Interfering; Scavenger Receptors, Class A; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability.
Topics: ADP Ribose Transferases; Angiogenesis Inhibitors; Atorvastatin; Botulinum Toxins; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Enzyme Inhibitors; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 9; Mevalonic Acid; Neovascularization, Physiologic; Nitrobenzenes; Polyisoprenyl Phosphates; Pyrroles; rho GTP-Binding Proteins; RNA, Messenger; Simvastatin; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Effects of the new immunosuppressive agent AEB071 on human immune cells.
Topics: CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cytokines; Dendritic Cells; Humans; Immunosuppressive Agents; Ionomycin; K562 Cells; Killer Cells, Natural; Leukocytes, Mononuclear; Protein Kinase C; Pyrroles; Quinazolines; Tetradecanoylphorbol Acetate | 2010 |
Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer.
Topics: Adult; Aged; Carbazoles; Carcinoma, Non-Small-Cell Lung; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Enzyme Activators; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prostaglandins E; Protein Kinase C; Pyrroles; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Xanthones | 2011 |
Effects of statins on matrix metalloproteinases and their endogenous inhibitors in human endothelial cells.
Topics: Atorvastatin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pravastatin; Pyrroles; Simvastatin; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Umbilical Veins | 2011 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells.
Topics: Acetylation; Cell Line, Tumor; Cell Proliferation; DNA-Directed RNA Polymerases; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Interleukin-8; Melanoma; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun; Pyrroles; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor TFIIB; Transcription, Genetic; Uveal Neoplasms | 2013 |
Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection.
Topics: Animals; Carbazoles; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; GTP-Binding Proteins; Indoles; Protein Glutamine gamma Glutamyltransferase 2; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transglutaminases | 2014 |
PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
Topics: Apoptosis; beta Catenin; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Microenvironment; Wnt Signaling Pathway | 2014 |
Medium-throughput ESR detection of superoxide production in undetached adherent cells using cyclic nitrone spin traps.
Topics: Animals; Antioxidants; beta-Cyclodextrins; Cell Adhesion; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Mice; Nitrogen Oxides; Organophosphonates; Oxygen; Pyrroles; RAW 264.7 Cells; Reactive Oxygen Species; Spin Labels; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate | 2015 |
Modulation of the EMT/MET process by pyrrole-imidazole polyamide targeting human transforming growth factor-β1.
Topics: Blotting, Western; Cadherins; Cell Line; Cells, Cultured; Cellular Reprogramming; Epithelial-Mesenchymal Transition; Fibroblasts; Gene Expression; Humans; Imidazoles; Induced Pluripotent Stem Cells; Microscopy, Confocal; Nylons; Promoter Regions, Genetic; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta1 | 2015 |
Anti-inflammatory activity effect of 2-substituted-1,4,5,6-tetrahydrocyclopenta[b]pyrrole on TPA-induced skin inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Cyclopentanes; Dermatitis; Mice; NF-kappa B; Pyrroles; Tetradecanoylphorbol Acetate | 2016 |
JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1.
Topics: Binding Sites; CD4 Antigens; CD4-Positive T-Lymphocytes; env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Interleukin-2; Janus Kinases; Nitriles; Piperidines; Pyrazoles; Pyrimidines; Pyrroles; Pyrrolidines; Signal Transduction; STAT Transcription Factors; Sulfonamides; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Virus Internalization; Virus Replication | 2017 |
Janus kinase inhibitors prevent migration of rheumatoid arthritis neutrophils towards interleukin-8, but do not inhibit priming of the respiratory burst or reactive oxygen species production.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azetidines; Case-Control Studies; Cell Movement; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Janus Kinases; Male; Middle Aged; Neutrophils; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Reactive Oxygen Species; Respiratory Burst; Sulfonamides; Tetradecanoylphorbol Acetate; United Kingdom | 2017 |
Synthesis and highly potent anti-inflammatory activity of licofelone- and ketorolac-based 1-arylpyrrolizin-3-ones.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Edema; Ketorolac; Lipopolysaccharides; Macrophages; Male; Mice; Molecular Docking Simulation; Molecular Structure; Nitric Oxide; Pyrroles; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2019 |