pyrroles has been researched along with staurosporine aglycone in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradbury, EM; Crissman, HA; Gadbois, DM; Tobey, RA | 1 |
| Hatase, O; Irino, S; Norman, AW; Taoka, T; Tasaka, T; Tokuda, M | 1 |
| Jikoh, Y; Nishio, H; Okugawa, K; Segawa, T | 1 |
| Abraham, I; McCroskey, MC; Sampson, KE | 1 |
| Abraham, I; Aristoff, PA; Laborde, AL; Sampson, KE; Shelly, JA; Skulnick, HI; Wolf, CL | 1 |
| Kubokawa, M; Kubota, T; Mori, Y | 1 |
| Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R | 1 |
| Ohuchi, K; Yamaki, K | 1 |
| Birdsall, NJ; Lazareno, S; Popham, A | 1 |
| Allen, FD; Dollé, JP; Lazarovici, P; Lelkes, PI; Rezvan, A | 1 |
| Brackenbury, WJ; Djamgoz, MB | 1 |
| Angeles, TS; Gessner, GW; Hudkins, RL; Johnson, NW; Mallamo, JP | 1 |
| Chae, CS; Chung, SC; Kim, TI; Lee, SH; Oh, KB; Park, JS; Shin, J; Yoon, KM | 1 |
| Asamizu, S; Igarashi, Y; Nagano, S; Onaka, H; Shiro, Y | 1 |
14 other study(ies) available for pyrroles and staurosporine aglycone
| Article | Year |
|---|---|
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.
Topics: Alkaloids; Carbazoles; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Humans; In Vitro Techniques; Indole Alkaloids; Indoles; Interphase; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine | 1992 |
Induction of differentiation of HL-60 cells by protein kinase C inhibitor, K252a.
Topics: Carbazoles; Cell Differentiation; Cell Division; DNA, Neoplasm; Humans; Indole Alkaloids; Indoles; Leukemia, Promyelocytic, Acute; Protein Kinase C; Protein Kinases; Pyrroles; Tumor Cells, Cultured | 1990 |
Effect of concanavalin A on serotonin transport into blood platelets: possible involvement of protein kinase C.
Topics: Alkaloids; Animals; Biological Transport, Active; Blood Platelets; Blood Proteins; Calcium; Calcium Radioisotopes; Carbazoles; Concanavalin A; In Vitro Techniques; Indole Alkaloids; Indoles; Lanthanum; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rabbits; Serotonin; Staurosporine | 1990 |
Identification of a 170 kDa membrane kinase with increased activity in KB-V1 multidrug resistant cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Calcium; Carbazoles; Carrier Proteins; Clone Cells; Cyclic AMP; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Indole Alkaloids; Indoles; KB Cells; Melanoma, Experimental; Membrane Glycoproteins; Mice; Neoplasm Proteins; Phosphatidylserines; Phosphorylation; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyrroles; Staurosporine; Transfection; Tumor Cells, Cultured; Tyrosine | 1993 |
K252a, KT5720, KT5926, and U98017 support paclitaxel (taxol)-dependent cells and synergize with paclitaxel.
Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbazoles; Cell Division; Cell Line; CHO Cells; Cricetinae; Drug Synergism; Indole Alkaloids; Indoles; Myosin-Light-Chain Kinase; Paclitaxel; Pyrroles; Staurosporine | 1994 |
Modulation of inwardly rectifying ATP-regulated K+ channel by phosphorylation process in opossum kidney cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Animals; Bucladesine; Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Indole Alkaloids; Indoles; Kidney; Opossums; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Potassium Channels; Protein Kinase Inhibitors; Pyrroles | 1997 |
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine | 1998 |
Participation of protein kinases in staurosporine-induced interleukin-6 production by rat peritoneal macrophages.
Topics: Animals; Carbazoles; Chromones; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Indole Alkaloids; Indoles; Interleukin-6; Isoquinolines; Macrophages, Peritoneal; Male; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Time Factors | 1999 |
Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Animals; Carbazoles; CHO Cells; Cricetinae; Enzyme Inhibitors; Indole Alkaloids; Indoles; N-Methylscopolamine; Pyrroles; Radioligand Assay; Receptors, Muscarinic; Staurosporine | 2000 |
Nerve growth factor-induced migration of endothelial cells.
Topics: Adrenal Medulla; Animals; Aorta; Carbazoles; Cell Line; Cell Movement; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Indole Alkaloids; Indoles; Mice; Models, Biological; Nerve Growth Factor; Pyrroles; Rats; Receptor, Nerve Growth Factor; Receptor, trkA; Recombinant Proteins; Reproducibility of Results; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Viperidae | 2005 |
Nerve growth factor enhances voltage-gated Na+ channel activity and Transwell migration in Mat-LyLu rat prostate cancer cell line.
Topics: Animals; Carbazoles; Cell Line, Tumor; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Indole Alkaloids; Indoles; Male; NAV1.7 Voltage-Gated Sodium Channel; Nerve Growth Factor; Patch-Clamp Techniques; Prostatic Neoplasms; Pyrroles; Rats; Receptors, Nerve Growth Factor; RNA, Messenger; Sodium Channels; Time Factors; Up-Regulation | 2007 |
Synthesis and mixed lineage kinase activity of pyrrolocarbazole and isoindolone analogs of (+)K-252a.
Topics: Animals; Carbazoles; CHO Cells; Cricetinae; Cricetulus; Heterocyclic Compounds, 4 or More Rings; Indole Alkaloids; Indoles; MAP Kinase Kinase Kinases; Models, Molecular; Pyrroles; Stereoisomerism; Structure-Activity Relationship | 2007 |
Production of chromopyrrolic acid by coexpression of inkOD in a heterologous host Streptomyces albus.
Topics: Carbazoles; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Design; Indole Alkaloids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Multigene Family; Pyrroles; Streptomyces; Tryptophan | 2009 |
Characterization and functional modification of StaC and RebC, which are involved in the pyrrole oxidation of indolocarbazole biosynthesis.
Topics: Amino Acid Sequence; Binding Sites; Carbazoles; Cloning, Molecular; Flavin-Adenine Dinucleotide; Indole Alkaloids; Indoles; Molecular Sequence Data; Molecular Structure; Oxidation-Reduction; Oxygenases; Pyrroles; Staurosporine; Streptomyces; Substrate Specificity | 2011 |