pyrroles has been researched along with sphingosine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malaquias, AT; Oliveira, MM | 1 |
| Fresco, P; Gonçalves, J; Pinto, E; Saraiva, L | 1 |
| Babita, K; Tiwary, AK | 1 |
| Hashimoto, T; Igarashi, J; Kosaka, H; Kubota, Y; Miyoshi, M | 1 |
| Caruso-Neves, C; Einicker-Lamas, M; Masuda, CA; Nascimento, MT; Oliveira, MM | 1 |
| Cole, GJ; Kim, MJ; Liu, IH; Zhang, C | 1 |
| Carrothers, TJ; Inaba, S; Moberly, JB; Rohatagi, S; Shimozato, T; Truitt, KE; Zahir, H | 1 |
| Adamowicz, JJ; Berdyshev, EV; Diab, KJ; Garrison, J; Gu, Y; Hubbard, WC; Kamocki, K; Petrache, I; Rajashekhar, G; Rush, NI; Schweitzer, KS; Skobeleva, A | 1 |
| Beerli, C; Bruns, C; Burkhart, C; Metzler, B; Morris, RE; Pally, C; Wagner, J; Weckbecker, G; Wieczorek, G | 1 |
| Bromberg, JS; Ding, Y; Shi, Q; Xu, J; Yin, N; Zhang, N | 1 |
| Baaj, Y; Cook-Moreau, J; Faucher-Durand, K; Fourcade, L; Funalot, B; Mollard, S; Mousseau, Y; Nizou, A; Plainard, X; Qiu, H; Richard, L; Sturtz, FG | 1 |
| Chen, S; Ford, DM; Moberly, JB; Mochizuki, T; Truitt, KE; Vollmer, TL; Zahir, H | 1 |
| Basmadjian, C; Buzard, D; Gharbaoui, T; Johnson, BR; Jones, RM; Kasem, M; Lopez, L; Schrader, TO; Sengupta, D | 1 |
| Cha, SS; Chen, CS; Choi, CK; Galie, PA; Nguyen, DH; Stapleton, SC; Yang, MT | 1 |
| Inaba, S; Kubota, K; Sakurai, H; Shinagawa, A; Takanaka, K | 1 |
| Abraham, C; Dulai, PS; Sandborn, WJ; Vermeire, S | 1 |
1 review(s) available for pyrroles and sphingosine
| Article | Year |
|---|---|
Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cytokines; Humans; Inflammatory Bowel Diseases; Interleukin-23; Janus Kinases; Lysophospholipids; Molecular Targeted Therapy; Oligonucleotides; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; Smad7 Protein; Sphingosine; Th17 Cells; Transforming Growth Factor beta; Ustekinumab | 2017 |
1 trial(s) available for pyrroles and sphingosine
| Article | Year |
|---|---|
Use of an exposure-response model to aid early drug development of an oral sphingosine 1-phosphate receptor modulator.
Topics: Administration, Oral; Adolescent; Adult; Amino Alcohols; CD4-Positive T-Lymphocytes; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lymphocyte Count; Lymphocyte Subsets; Lymphocytes; Lysophospholipids; Male; Middle Aged; Models, Biological; Prodrugs; Pyrroles; Receptors, Lysosphingolipid; Sphingosine; Young Adult | 2009 |
14 other study(ies) available for pyrroles and sphingosine
| Article | Year |
|---|---|
Phospholipid signalling pathways in Trypanosoma cruzi growth control.
Topics: Adenylate Cyclase Toxin; Animals; Benzylamines; Carbazoles; Cell Division; Culture Media; Cyclic AMP; Dose-Response Relationship, Drug; Estrenes; Indoles; Lysophospholipids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Protein Kinases; Pyrroles; Pyrrolidinones; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides; Trypanosoma cruzi; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Isoform-selectivity of PKC inhibitors acting at the regulatory and catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta.
Topics: Acetophenones; Alkaloids; Animals; Benzophenanthridines; Benzopyrans; Catalysis; Enzyme Inhibitors; Escherichia coli; Indoles; Isoenzymes; Phenanthridines; Piperidines; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Pyrroles; Saccharomyces cerevisiae; Sphingosine; Tamoxifen; Yeasts | 2003 |
Skin lipid synthesis inhibition: a possible means for enhancing percutaneous delivery of levodopa.
Topics: Administration, Cutaneous; Animals; Anticholesteremic Agents; Antiparkinson Agents; Atorvastatin; beta-Alanine; Calcium Channel Blockers; Calcium Chloride; Cholesterol; Dose-Response Relationship, Drug; Ethanol; Female; Heptanoic Acids; In Vitro Techniques; Levodopa; Male; Pyrroles; Rats; Rats, Wistar; Serine C-Palmitoyltransferase; Skin; Sphingosine; Time Factors; Verapamil | 2004 |
Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins.
Topics: Alkyl and Aryl Transferases; Animals; Atorvastatin; Blotting, Western; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, HDL; Lysophospholipids; Mevalonic Acid; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pyrroles; Quinolines; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sphingosine; Stimulation, Chemical | 2007 |
Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C.
Topics: Animals; Biological Transport; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Inositol; Kinetics; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sphingosine; Staurosporine; Trypanosoma cruzi | 2007 |
Retina development in zebrafish requires the heparan sulfate proteoglycan agrin.
Topics: Acridine Orange; Agrin; Animals; Animals, Genetically Modified; Cell Death; ELAV Proteins; ELAV-Like Protein 3; Embryo, Nonmammalian; Enzyme Inhibitors; Fibroblast Growth Factor 3; GAP-43 Protein; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Heparan Sulfate Proteoglycans; Oligonucleotides, Antisense; Pyrroles; Retina; Sphingosine; Superior Colliculi; Transcription Factor Brn-3C; Zebrafish; Zebrafish Proteins | 2008 |
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.
Topics: Animals; Apoptosis; Blotting, Western; Cells, Cultured; Ceramides; Disease Models, Animal; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Indoles; Lysophospholipids; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Propylene Glycols; Pulmonary Alveoli; Pulmonary Emphysema; Pyrroles; Receptors, Lysosphingolipid; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sphingosine | 2010 |
Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.
Topics: Animals; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Everolimus; Fingolimod Hydrochloride; Heart Transplantation; Immunosuppressive Agents; Male; Propylene Glycols; Protein Kinase C; Pyrroles; Quinazolines; Rats; Rats, Inbred Lew; Rats, Wistar; Sirolimus; Sphingosine | 2010 |
Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival.
Topics: Animals; Antibodies, Monoclonal; Diabetes Mellitus, Experimental; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Immunosuppressive Agents; Indoles; Islets of Langerhans Transplantation; Lymphangiogenesis; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Propylene Glycols; Pyrroles; Sphingosine; Sunitinib; T-Lymphocytes; Transplantation Tolerance; Transplantation, Homologous; Vascular Endothelial Growth Factor Receptor-3 | 2011 |
Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Carcinoma 256, Walker; Cell Movement; Cells, Cultured; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fingolimod Hydrochloride; Indoles; Male; Mammary Neoplasms, Experimental; Myocytes, Smooth Muscle; Neoplasm Transplantation; Propylene Glycols; Proto-Oncogene Proteins c-sis; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Statistics, Nonparametric; Sunitinib; Tumor Burden; Tyrphostins | 2012 |
Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: results from a 12-week, open-label pilot study in multiple sclerosis patients.
Topics: Administration, Oral; Amino Alcohols; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Immunologic; Down-Regulation; Humans; Lymphocyte Subsets; Lymphopenia; Lysophospholipids; Multiple Sclerosis; Pilot Projects; Pyrroles; Receptors, Lysosphingolipid; Sphingosine | 2012 |
Complementary asymmetric routes to (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate.
Topics: Acetates; Catalysis; Fingolimod Hydrochloride; Indoles; Molecular Structure; Propylene Glycols; Pyrroles; Receptors, Lysosphingolipid; Sphingosine; Stereoisomerism | 2012 |
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro.
Topics: Biomimetics; Cell Polarity; Dimethylpolysiloxanes; Fingolimod Hydrochloride; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Lysophospholipids; Microfluidics; Models, Biological; Morphogenesis; Neovascularization, Physiologic; Propylene Glycols; Pseudopodia; Pyrroles; Sphingosine; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Identification of a metabolizing enzyme in human kidney by proteomic correlation profiling.
Topics: Alkaline Phosphatase; Amino Alcohols; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Isoenzymes; Kidney; Propylene Glycols; Proteomics; Pyrroles; Sphingosine | 2013 |