pyrroles has been researched along with sildenafil citrate in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bendhack, LM; Castro, MM; Nagassaki, S; Rascado, RR; Rizzi, E; Tanus-Santos, JE | 1 |
| Atar, S; Birnbaum, Y; Freeberg, SY; Huang, MH; Rahman, AM; Rosanio, S; Uretsky, BF; Ye, Y | 1 |
| Bradbury, D; Herrmann, HC; Kimmel, SE; Levine, LA; Macaluso, J; Mohler, ER; Schwartz, S; Walsh, M | 1 |
| Kukreja, RC | 1 |
| Bank, AJ; Billups, KL; Crawford, WW; Kaiser, DR; Kelly, AS; Schow, DA; Waxman, B | 1 |
| Byun, SS; Han, BK; Hong, SK; Jeong, SJ; Lee, SE | 1 |
| Gokkaya, SC; Guzel, O; Hakan Koyuncu, H; Levent Ozdal, O; Memis, A; Ozden, C | 1 |
| Chavalmane, AK; Fibbi, B; Filippi, S; Forti, G; Maggi, M; Morelli, A; Sarchielli, E; Silvestrini, E; Vannelli, GB; Vignozzi, L; Zhang, XH | 1 |
| Cui, JH; Kim, WM; Yoon, MH | 1 |
| Archimandritis, A; Frenzilli, G; Peluso, C; Rocco, L; Stingo, V; Zito, G | 1 |
| Czaikoski, PG; Dias-Junior, CA; Neto-Neves, EM; Pereira, RP; Spiller, F; Tanus-Santos, JE; Uzuelli, JA | 1 |
| Waeber, C; Wang, QM; Wei, Y; Zheng, Y | 1 |
| Ghofrani, HA; Grimminger, F; Kalymbetov, A; Kojonazarov, B; Kretschmer, A; Lang, M; Schermuly, RT; Seeger, W; Stasch, JP; Tian, X; Weissmann, N | 1 |
| Ceron, CS; Gerlach, RF; Guimarães, DA; Pinheiro, LC; Rizzi, E; Tanus-Santos, JE | 1 |
| Arrowood, CA; Honeycutt, W; Howard, L; Hurwitz, HI; Latta, K; Meadows, KL; Niedzwiecki, D; Rushing, C | 1 |
| Jia, L; Peng, S; Wang, L; Wu, C; Yang, J; Yang, X; Yin, J; Yuan, Z; Zhao, S | 1 |
| Chen, J; Chen, Y; Geng, H; Guo, X; Huang, Y; Lai, Z; Luo, HB; Wu, D; Wu, Y; Yu, Y; Zhang, C; Zhang, T | 1 |
| Adão, R; Bialesova, L; Brás-Silva, C; Kinsella, BT; Mendes-Ferreira, P; Mulvaney, EP; Reid, HM | 1 |
| Aguirre, JI; Aronovitz, MJ; Baca, P; Baumgartner, RA; Blanton, RM; Calamaras, TD; Davis, RJ; Jaffe, IZ; Karas, RH; Kim, SK; Lin, W; Liu, P; Martin, GL; McCarthy, JC; McLaughlin, AL; Pande, S; Richards, DA; Tam, K; Wang, GR | 1 |
| Chapman, RW; Chun, D; Cipolla, D; Corboz, MR; Gauani, H; Li, Z; Malinin, V; Perkins, WR; Plaunt, AJ | 1 |
4 trial(s) available for pyrroles and sildenafil citrate
| Article | Year |
|---|---|
Can atorvastatin improve the response to sildenafil in men with erectile dysfunction not initially responsive to sildenafil? Hypothesis and pilot trial results.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Erectile Dysfunction; Heptanoic Acids; Humans; Male; Middle Aged; Penile Erection; Pilot Projects; Piperazines; Purines; Pyrroles; Sildenafil Citrate; Sulfones; Treatment Outcome | 2006 |
The effects of quinapril and atorvastatin on the responsiveness to sildenafil in men with erectile dysfunction.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atorvastatin; Double-Blind Method; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Impotence, Vasculogenic; Male; Middle Aged; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrroles; Quinapril; Sildenafil Citrate; Sulfones; Surveys and Questionnaires; Tetrahydroisoquinolines; Time Factors; Treatment Failure; Treatment Outcome | 2006 |
Effect of statin therapy on early return of potency after nerve sparing radical retropubic prostatectomy.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aged; Atorvastatin; Cyclic Nucleotide Phosphodiesterases, Type 5; Denervation; Drug Therapy, Combination; Erectile Dysfunction; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microsurgery; Middle Aged; Penile Erection; Peripheral Nerves; Piperazines; Postoperative Complications; Prospective Studies; Prostate; Prostatectomy; Prostatic Neoplasms; Purines; Pyrroles; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2007 |
Treatment of palmar-plantar erythrodysesthesia (PPE) with topical sildenafil: a pilot study.
Topics: Adult; Aged; Antineoplastic Agents; Capecitabine; Deoxycytidine; Double-Blind Method; Female; Fluorouracil; Hand-Foot Syndrome; Humans; Indoles; Male; Middle Aged; Neoplasms; Pilot Projects; Piperazines; Placebos; Protein Kinase Inhibitors; Purines; Pyrroles; Sildenafil Citrate; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factor A | 2015 |
16 other study(ies) available for pyrroles and sildenafil citrate
| Article | Year |
|---|---|
Atorvastatin enhances sildenafil-induced vasodilation through nitric oxide-mediated mechanisms.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Aorta, Thoracic; Atorvastatin; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heptanoic Acids; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Acid; Nitric Oxide Synthase; Nitrites; Piperazines; Purines; Pyrroles; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2004 |
Enhanced cardioprotection against ischemia-reperfusion injury with combining sildenafil with low-dose atorvastatin.
Topics: Amidines; Animals; Atorvastatin; Benzylamines; Cardiotonic Agents; Drug Synergism; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Phosphorylation; Piperazines; Purines; Pyrroles; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Up-Regulation | 2006 |
Synergistic effects of atorvastatin and sildenafil in cardioprotection--role of NO.
Topics: Animals; Atorvastatin; Cardiotonic Agents; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Reperfusion Injury; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrroles; Sildenafil Citrate; Sulfones | 2006 |
Effect of correcting serum cholesterol levels on erectile function in patients with vasculogenic erectile dysfunction.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Heptanoic Acids; Humans; Hypercholesterolemia; Impotence, Vasculogenic; Male; Middle Aged; Penile Erection; Phosphodiesterase Inhibitors; Piperazines; Purines; Pyrroles; Sildenafil Citrate; Sulfones; Ultrasonography, Doppler, Duplex | 2008 |
Atorvastatin ameliorates sildenafil-induced penile erections in experimental diabetes by inhibiting diabetes-induced RhoA/Rho-kinase signaling hyperactivation.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Penile Erection; Phosphodiesterase Inhibitors; Phosphorylation; Piperazines; Purines; Pyrroles; Rabbits; rho-Associated Kinases; Signal Transduction; Sildenafil Citrate; Sulfones | 2009 |
Role of PKG-L-type calcium channels in the antinociceptive effect of intrathecal sildenafil.
Topics: Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Male; Pain; Pain Measurement; Piperazines; Protein Kinase Inhibitors; Purines; Pyrroles; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones | 2010 |
Genotoxic effects in fish induced by pharmacological agents present in the sewage of some Italian water-treatment plants.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Comet Assay; DNA Damage; Environmental Monitoring; Gemfibrozil; Heptanoic Acids; Hypolipidemic Agents; Italy; Mutagens; Piperazines; Purines; Pyrroles; Random Amplified Polymorphic DNA Technique; Sewage; Sildenafil Citrate; Sulfones; Vasodilator Agents; Waste Disposal, Fluid; Water Pollutants, Chemical; Zebrafish | 2012 |
Sildenafil improves the beneficial hemodynamic effects exerted by atorvastatin during acute pulmonary thromboembolism.
Topics: Acute Disease; Animals; Atorvastatin; Bronchoalveolar Lavage; Drug Synergism; Enzyme Activation; Heart Ventricles; Hemodynamics; Heptanoic Acids; Lipid Peroxidation; Lung; Male; Matrix Metalloproteinases; Myocytes, Cardiac; Neutrophils; Oxidative Stress; Piperazines; Pulmonary Embolism; Purines; Pyrroles; Sildenafil Citrate; Sulfones | 2011 |
Efficacy of combined atorvastatin and sildenafil in promoting recovery after ischemic stroke in mice.
Topics: Animals; Atorvastatin; Behavior, Animal; Drug Therapy, Combination; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neuropsychological Tests; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrroles; Recovery of Function; Sildenafil Citrate; Stroke; Sulfones | 2013 |
The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats.
Topics: Animals; Apoptosis; Blood Pressure; Blotting, Western; Caspase 3; Cell Proliferation; Cyclic GMP; Guanylate Cyclase; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Indoles; Lung; Male; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Pyrazoles; Pyrimidines; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfones; Time Factors; Treatment Outcome | 2012 |
Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension.
Topics: Animals; Aorta; Atorvastatin; Blood Pressure; Body Weight; Disease Models, Animal; Drug Therapy, Combination; Heptanoic Acids; Hypertension, Renovascular; Male; Nitric Oxide; Piperazines; Purines; Pyrroles; Rats; Rats, Wistar; Sildenafil Citrate; Sulfonamides | 2013 |
NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil.
Topics: Animals; Cell Line; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Humans; Inflammation Mediators; Lipopolysaccharides; Mice; Microglia; Neurotoxins; NF-kappa B; Phosphodiesterase Inhibitors; Pyrimidinones; Pyrroles; RNA Interference; RNA, Messenger; Sildenafil Citrate; Up-Regulation | 2016 |
Discovery and Optimization of Chromeno[2,3-c]pyrrol-9(2H)-ones as Novel Selective and Orally Bioavailable Phosphodiesterase 5 Inhibitors for the Treatment of Pulmonary Arterial Hypertension.
Topics: Animals; Catalytic Domain; CHO Cells; Chromones; Cricetulus; Cytochrome P-450 CYP1A2 Inhibitors; Drug Stability; ERG1 Potassium Channel; Female; Humans; Hypertension, Pulmonary; Male; Mice; Microsomes, Liver; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphodiesterase 5 Inhibitors; Pyrroles; Rats, Sprague-Dawley; Rats, Wistar; Sildenafil Citrate; Structure-Activity Relationship | 2017 |
Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with sildenafil, in the sugen/hypoxia-induced model of pulmonary arterial hypertension.
Topics: Angiogenesis Inhibitors; Animals; Drug Therapy, Combination; Hypoxia; Indoles; Male; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Wistar; Receptors, Thromboxane A2, Prostaglandin H2; Sildenafil Citrate; Treatment Outcome; Vasodilator Agents | 2020 |
MLK3 mediates impact of PKG1α on cardiac function and controls blood pressure through separate mechanisms.
Topics: Animals; Aorta; Blood Pressure; Cyclic GMP-Dependent Protein Kinase Type I; Heart Failure; HEK293 Cells; Humans; Hypertension; Male; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase Kinase Kinase 11; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrroles; Sildenafil Citrate; Vascular Stiffness; Vasodilator Agents; Ventricular Dysfunction, Left | 2021 |
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.
Topics: Administration, Inhalation; Administration, Oral; Animals; Collagen; Disease Models, Animal; Epoprostenol; Heart; Hemodynamics; Hypoxia; Indoles; Male; Myocardium; Phosphodiesterase 5 Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Sildenafil Citrate; Vascular Remodeling; Vasodilator Agents | 2022 |