Page last updated: 2024-08-18

pyrroles and sesquiterpenes

pyrroles has been researched along with sesquiterpenes in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's1 (2.78)18.2507
2000's21 (58.33)29.6817
2010's11 (30.56)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Basel, CT1
Fried, HM; Warner, JR1
Alonso, C; Blanco-Colio, LM; Díaz, C; Egido, J; Guijarro, C; Hernández, G; Ortego, M; Ortiz, A; Plaza, JJ1
Abman, SH; Gebb, S; Hirth, KP; Jakkula, M; Le Cras, TD; Tuder, RM; Voelkel, NF1
Bamidele-Sanni, S; Bermejo, FA; García-Granda, S; Rico-Ferreira, R1
Blanco-Colio, LM; Egido, J; Hernández-Presa, MA; Ortego, M; Pascual, A; Plaza, JJ; Villa, A1
Ang, KK; Buss, AD; Flotow, H; Hamann, MT; Hu, JF; Kelly, M; Leong, CY; Ng, SB; Peng, JN; Schetz, JA; Wilkins, SP1
Bäckman, U; Christofferson, R; Jonsson, E; Larsson, R; Svensson, A1
Bailly, C; Lansiaux, A1
Fyhrquist, F; Nyman, T; Saijonmaa, O; Stewen, P1
Bösel, J; Dirnagl, U; Endres, M; Megow, D; Schulz, JG; Stoeckel, M1
Jono, S; Kizu, A; Koyama, H; Nishizawa, Y; Okuno, Y; Shioi, A1
Arii, K; Hashimoto, K; Ikeda, Y; Kumon, Y; Osaki, F; Ota, K; Suehiro, T1
Argmann, CA; Edwards, JY; Hegele, RA; Huff, MW; O'Neil, CH; Pickering, JG; Sawyez, CG1
Bellows, C; Lam, KS; Liu, J; Macherla, VR; Nicholson, B; Potts, BC; Teisan, S1
Fujita, K; Kubo, I1
Laguna, JC; Merlos, M; Planavila, A; Sánchez, RM; Vázquez-Carrera, M1
Li, Q; Lin, AJ; Skillman, DS; Smith, K; Xie, LH; Zhang, J1
Fyhrquist, F; Nyman, T; Saijonmaa, O1
Hill, JS; Qiu, G1
Fanburg, BL; Finlay, GA; Kwiatkowski, DJ; Liu, Y; Malhowski, AJ; Toksoz, D1
Abe, M; Fujita, M; Hasegawa, K; Kawamura, T; Kita, T; Morimoto, T; Ono, K; Satoh, N; Shimatsu, A; Takaya, T; Wada, H1
Caruthers, SD; Lanza, GM; Wickline, SA; Williams, TA; Winter, PM; Zhang, H1
Arbustini, E; Gambarin, FI1
Dickschat, JS; Riclea, R1
Ping, D; Qin, X; Xiao, H; Zuo, K1
Li, ZH; Moreno, SN; Ramakrishnan, S; Striepen, B1
Hayakawa, T; Matsuda, H; Miki, H; Miyashita, Y; Morikawa, T; Muraoka, O; Nakanishi, Y; Nakashima, S; Ninomiya, K; Yoshikawa, M1
Alfonso, A; Alonso, E; Botana, LM; Ebel, R; Houssen, WE; Jaspars, M; Leirós, M; Rateb, ME1
Cagnon, VH; Hetzl, AC; Kido, LA; Montico, F1
Burth, P; Calixto, JB; Dasari, R; De Carvalho, A; De La Chapa, JJ; Dybdal-Hargreaves, NF; Evidente, A; Frolova, LV; Gautier, M; Glass, R; Gonzales, CB; Hague, F; Kälin, RE; Kiss, R; Kornienko, A; Mathieu, V; Medellin, DC; Middleton, KN; Munirathinam, G; Pelly, SC; Pillai, A; Rogelj, S; Rossato, MF; van Otterlo, WA; Volmar, MN1
John, E; Lopez-Ruiz, F; Mousley, CJ; Oliver, RP; Rybak, K; Tan, KC1
Kishimoto, S; Sato, M; Tsunematsu, Y; Watanabe, K1
Hill, RA; Sutherland, A1
Kaufman, TS; Larghi, EL; Vargas, DF1
Bhandari, MR; Doundoulakis, T; Gout, D; Lovely, CJ; Singh, RP; Torres, FM1

Reviews

3 review(s) available for pyrroles and sesquiterpenes

ArticleYear
The antibiotic complex of the verrucarins and roridins.
    Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles, 1974, Volume: 31, Issue:0

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Benzopyrans; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chick Embryo; Dogs; Haplorhini; Lactones; Lethal Dose 50; Mast-Cell Sarcoma; Mice; Microbial Sensitivity Tests; Oxepins; Pyrroles; Rats; Sarcoma, Experimental; Sarcoma, Yoshida; Sesquiterpenes; Sterols; Structure-Activity Relationship

1974
Hot off the press.
    Natural product reports, 2018, 02-21, Volume: 35, Issue:2

    Topics: Actinobacteria; Actinomycetales; Alkaloids; Biochemistry; Biological Products; Molecular Structure; Multigene Family; Oxazoles; Phenylpropionates; Pyrones; Pyrroles; Sesquiterpenes

2018
The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields.
    Natural product reports, 2019, 02-20, Volume: 36, Issue:2

    Topics: Alkaloids; Aza Compounds; Biological Products; Chemistry Techniques, Synthetic; Cyclization; Histamine Agonists; Piperidines; Pyridines; Pyrroles; Quinazolines; Quinolizines; Sesquiterpenes

2019

Other Studies

33 other study(ies) available for pyrroles and sesquiterpenes

ArticleYear
Cloning of yeast gene for trichodermin resistance and ribosomal protein L3.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:1

    Topics: Anisomycin; Cloning, Molecular; Cycloheximide; DNA, Fungal; Drug Resistance, Microbial; Plasmids; Pyrroles; Ribosomal Protein L3; Ribosomal Proteins; Saccharomyces cerevisiae; Sesquiterpenes; Transformation, Genetic; Trichodermin

1981
3-Hydroxy-3-methylglutaryl coenzyme a reductase and isoprenylation inhibitors induce apoptosis of vascular smooth muscle cells in culture.
    Circulation research, 1998, Sep-07, Volume: 83, Issue:5

    Topics: Animals; Apoptosis; Atorvastatin; Cell Survival; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Polyisoprenyl Phosphates; Protein Prenylation; Pyrroles; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Solubility

1998
Inhibition of angiogenesis decreases alveolarization in the developing rat lung.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Barium Sulfate; Body Weight; Cyclohexanes; Fatty Acids, Unsaturated; Gelatin; Heart; Indoles; Injections, Intra-Arterial; Lung; Neovascularization, Physiologic; Organ Size; Pulmonary Alveoli; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sesquiterpenes; Thalidomide

2000
Total synthesis of (+)-ampullicin and (+)-isoampullicin: two fungal metabolites with growth regulatory activity isolated from Ampulliferina sp. 27.
    The Journal of organic chemistry, 2001, Dec-14, Volume: 66, Issue:25

    Topics: Crystallography, X-Ray; Fungi; Growth Substances; Indicators and Reagents; Magnetic Resonance Spectroscopy; Pyrroles; Sesquiterpenes

2001
3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
    Atherosclerosis, 2002, Volume: 161, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Atorvastatin; Caspase Inhibitors; Caspases; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Muscle, Smooth, Vascular; Polyisoprenyl Phosphates; Protein Prenylation; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Rabbits; Rats; rhoA GTP-Binding Protein; Sesquiterpenes; Simvastatin; Time Factors

2002
New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea.
    Journal of natural products, 2002, Volume: 65, Issue:4

    Topics: Animals; Anti-Infective Agents; Antimalarials; Aspartic Acid Endopeptidases; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; Humans; Indole Alkaloids; Jamaica; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Protozoan Proteins; Pyrroles; Quinones; Receptors, Serotonin; Sesquiterpenes

2002
CHS 828 inhibits neuroblastoma growth in mice alone and in combination with antiangiogenic drugs.
    Pediatric research, 2002, Volume: 51, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Cyanides; Cyclohexanes; Guanidines; Humans; Indoles; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Neuroblastoma; O-(Chloroacetylcarbamoyl)fumagillol; Pyrroles; Remission Induction; Sesquiterpenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2002
[Perspectives on the oncologist pharmacopoeia].
    Bulletin du cancer, 2003, Volume: 90, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Boronic Acids; Bortezomib; Dioxoles; Indoles; Isoquinolines; Neoplasms; Organoplatinum Compounds; Protease Inhibitors; Pyrazines; Pyrroles; Quinazolines; Sesquiterpenes; Tetrahydroisoquinolines; Trabectedin

2003
Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:6

    Topics: Amides; Atorvastatin; Cell Division; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Mevalonic Acid; Peptidyl-Dipeptidase A; Phosphorylation; Polyisoprenyl Phosphates; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; rho-Associated Kinases; RNA, Messenger; Sesquiterpenes; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A

2004
HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis.
    Journal of neurochemistry, 2004, Volume: 89, Issue:1

    Topics: Animals; Atorvastatin; Cell Death; Cell Survival; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Neurites; Neurons; Polyisoprenyl Phosphates; Pyrroles; Rats; Sesquiterpenes; Squalene

2004
Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators.
    Journal of cellular biochemistry, 2004, Nov-15, Volume: 93, Issue:5

    Topics: Alkaline Phosphatase; Atorvastatin; Calcinosis; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mevalonic Acid; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polyisoprenyl Phosphates; Pyridines; Pyrroles; Sesquiterpenes

2004
Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:2

    Topics: Alkyl and Aryl Transferases; Aryldialkylphosphatase; Atorvastatin; Cell Line; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Farnesyltranstransferase; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Luciferases; Mevalonic Acid; Plasmids; Polyisoprenyl Phosphates; Pyrroles; Quinolines; Sesquiterpenes; Sp1 Transcription Factor; Time Factors; Transcriptional Activation; Transfection

2005
Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: Animals; Apolipoprotein A-I; Atorvastatin; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Genes, Dominant; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipoproteins; Macrophages; Mevalonic Acid; Mice; Models, Biological; Phosphorylation; Polyisoprenyl Phosphates; PPAR gamma; Pyrroles; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Transfection; Up-Regulation

2005
Glaciapyrroles A, B, and C, pyrrolosesquiterpenes from a Streptomyces sp. isolated from an Alaskan marine sediment.
    Journal of natural products, 2005, Volume: 68, Issue:5

    Topics: Alaska; Geologic Sediments; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Pyrroles; Sesquiterpenes; Streptomyces

2005
Multifunctional action of antifungal polygodial against Saccharomyces cerevisiae: involvement of pyrrole formation on cell surface in antifungal action.
    Bioorganic & medicinal chemistry, 2005, Dec-15, Volume: 13, Issue:24

    Topics: Amines; Antifungal Agents; Cell Survival; Culture Media; Molecular Structure; Phospholipids; Pyrroles; Saccharomyces cerevisiae; Sesquiterpenes

2005
Atorvastatin prevents peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells.
    Biochimica et biophysica acta, 2005, Sep-15, Volume: 1736, Issue:2

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cell Line; Chemokine CCL2; Down-Regulation; Fatty Acids; Heptanoic Acids; Lipopolysaccharides; Muscle Cells; NF-kappa B; PPAR gamma; PPAR-beta; Protein Binding; Protein Kinases; Pyrroles; Rats; Sesquiterpenes; Transcription Factors; Transcriptional Activation

2005
New potential antimalarial agents: therapeutic-index evaluation of pyrroloquinazolinediamine and its prodrugs in a rat model of severe malaria.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Malaria; Maximum Tolerated Dose; Parasitemia; Plasmodium berghei; Prodrugs; Pyrroles; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Therapeutic Equivalency

2006
Atorvastatin inhibits angiotensin-converting enzyme induction in differentiating human macrophages.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:4

    Topics: Adolescent; Adult; Aged; Atorvastatin; Cell Differentiation; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Macrophages; Mevalonic Acid; Middle Aged; Peptidyl-Dipeptidase A; Phosphorylation; Polyisoprenyl Phosphates; Protein Kinase C; Pyrroles; RNA, Messenger; Sesquiterpenes; Terpenes; Up-Regulation

2007
Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages.
    Journal of lipid research, 2007, Volume: 48, Issue:10

    Topics: Animals; Atorvastatin; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipase; Lipoprotein Lipase; Liver X Receptors; Macrophages; NF-kappa B; Orphan Nuclear Receptors; Polyisoprenyl Phosphates; Pyrroles; Receptors, Cytoplasmic and Nuclear; Sesquiterpenes; Simvastatin

2007
Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Animals; Atorvastatin; Cell Growth Processes; Drug Interactions; Female; Heptanoic Acids; Male; Mice; Monomeric GTP-Binding Proteins; Neuropeptides; Phosphorylation; Polyisoprenyl Phosphates; Prenylation; Protein Kinases; Pyrroles; Ras Homolog Enriched in Brain Protein; Rats; rho GTP-Binding Proteins; Ribosomal Protein S6 Kinases; Sesquiterpenes; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2007
Statins activate GATA-6 and induce differentiated vascular smooth muscle cells.
    Biochemical and biophysical research communications, 2008, Oct-03, Volume: 374, Issue:4

    Topics: Actins; Amino Acid Motifs; Atorvastatin; Cell Differentiation; Cell Proliferation; Diterpenes; DNA Replication; GATA6 Transcription Factor; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nucleic Acid Synthesis Inhibitors; Polyisoprenyl Phosphates; Pyrroles; Sesquiterpenes; Simvastatin; Transcription, Genetic

2008
Antiangiogenic synergism of integrin-targeted fumagillin nanoparticles and atorvastatin in atherosclerosis.
    JACC. Cardiovascular imaging, 2008, Volume: 1, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Atherosclerosis; Atorvastatin; Carbocyanines; Cyclohexanes; Disease Models, Animal; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Unsaturated; Heptanoic Acids; Heterocyclic Compounds, 1-Ring; Integrin alphaVbeta3; Liver; Magnetic Resonance Imaging; Nanoparticles; Neovascularization, Pathologic; Pyrroles; Rabbits; Sesquiterpenes; Time Factors

2008
Theranostic strategy against plaque angiogenesis.
    JACC. Cardiovascular imaging, 2008, Volume: 1, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Atherosclerosis; Atorvastatin; Carbocyanines; Cyclohexanes; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Unsaturated; Heptanoic Acids; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Nanoparticles; Neovascularization, Pathologic; Pyrroles; Sesquiterpenes; Time Factors

2008
The absolute configuration of the pyrrolosesquiterpenoid glaciapyrrol A.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Oct-10, Volume: 17, Issue:42

    Topics: Acyclic Monoterpenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Pyrroles; Sesquiterpenes; Stereoisomerism; Streptomyces; Terpenes

2011
Inhibition of Rho and Rac geranylgeranylation by atorvastatin is critical for preservation of endothelial junction integrity.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Antigens, CD; Atorvastatin; Cadherins; cdc42 GTP-Binding Protein; Guanosine Triphosphate; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Junctions; Interleukin-6; Interleukin-8; Lipopolysaccharides; Mevalonic Acid; Polyisoprenyl Phosphates; Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrroles; rho-Associated Kinases; Sesquiterpenes; Thrombin

2013
Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin.
    PLoS pathogens, 2013, Volume: 9, Issue:10

    Topics: Animals; Apicoplasts; Atorvastatin; Diphosphates; Diterpenes; Farnesyltranstransferase; Female; Gene Knockdown Techniques; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred BALB C; Polyisoprenyl Phosphates; Protozoan Proteins; Pyrroles; Sesquiterpenes; Toxoplasma; Toxoplasmosis

2013
Dimeric pyrrolidinoindoline-type alkaloids with melanogenesis inhibitory activity in flower buds of Chimonanthus praecox.
    Journal of natural medicines, 2014, Volume: 68, Issue:3

    Topics: Alkaloids; Animals; Calycanthaceae; Cell Line, Tumor; Dimerization; Flowers; Indoles; Melanins; Mice; Monophenol Monooxygenase; Pyrroles; Sesquiterpenes

2014
Bromoalkaloids protect primary cortical neurons from induced oxidative stress.
    ACS chemical neuroscience, 2015, Feb-18, Volume: 6, Issue:2

    Topics: Alkaloids; Animals; Antioxidant Response Elements; Azepines; Blotting, Western; Cell Membrane; Cell Survival; Cells, Cultured; Cerebral Cortex; Lipid Peroxidation; Mice; Microscopy, Confocal; Mitochondria; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Pyrroles; Sesquiterpenes; Signal Transduction

2015
Prostatic angiogenic responses in late life: antiangiogenic therapy influences and relation with the glandular microenvironment in the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
    The Prostate, 2015, Apr-01, Volume: 75, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Angiogenesis Inhibitors; Animals; Blotting, Western; Cyclohexanes; Disease Models, Animal; Endostatins; Fibroblast Growth Factor 2; Finasteride; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indoles; Male; Mice; Mice, Transgenic; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Prostatic Neoplasms; Pyrroles; Sesquiterpenes; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2015
Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.
    European journal of medicinal chemistry, 2015, Oct-20, Volume: 103

    Topics: Amines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Polygonum; Pyrroles; Sesquiterpenes; Structure-Activity Relationship

2015
Dissecting the role of histidine kinase and HOG1 mitogen-activated protein kinase signalling in stress tolerance and pathogenicity of Parastagonospora nodorum on wheat.
    Microbiology (Reading, England), 2016, Volume: 162, Issue:6

    Topics: Ascomycota; Benzidines; Benzoxazoles; Drug Resistance, Fungal; Fungicides, Industrial; Gene Deletion; Heat-Shock Response; Histidine Kinase; Hot Temperature; Mitogen-Activated Protein Kinases; Phytoalexins; Plant Diseases; Protein Serine-Threonine Kinases; Pyrroles; Sesquiterpenes; Signal Transduction; Triticum

2016
Elucidation of Biosynthetic Pathways of Natural Products.
    Chemical record (New York, N.Y.), 2017, Volume: 17, Issue:11

    Topics: Biological Products; Biosynthetic Pathways; Cyclohexanes; Fatty Acids, Unsaturated; Fungi; Genes, Fungal; Heterocyclic Compounds, 4 or More Rings; Hydroxyquinolines; Models, Molecular; Piperazines; Pyrones; Pyrroles; Secondary Metabolism; Sesquiterpenes; Spiro Compounds

2017
Total Synthesis of (±)-2-Debromohymenin via Gold-Catalyzed Intramolecular Alkyne Hydroarylation.
    Organic letters, 2020, 05-01, Volume: 22, Issue:9

    Topics: Alkynes; Azepines; Carbon Monoxide; Catalysis; Chemistry Techniques, Synthetic; Cyclization; Gold; Hydrocarbons, Brominated; Molybdenum; Pyrroles; Sesquiterpenes

2020