Page last updated: 2024-08-18

pyrroles and sapropterin

pyrroles has been researched along with sapropterin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ding, QF; Fukatsu, A; Hayashi, T; Iguchi, A; Miyazaki, A; Nomura, T; Packiasamy, AR; Shiraishi, H1
Gorren, AC; Mayer, B; Nedeianu, S; Pignitter, M; Schmidt, K1
Bauersachs, J; Brandt, M; Closs, E; Daiber, A; Ertl, G; Förstermann, U; Münzel, T; Oelze, M; Thum, T; Wenzel, P; Xu, J; Zou, MH1
Hirata, K; Inoue, N; Kawashima, S; Masano, T; Nakajima, K; Nishimura, K; Sasaki, N; Satomi-Kobayashi, S; Shinohara, M; Sugiyama, D; Takaya, T; Takeda, M; Tawa, H; Toh, R; Yamashita, T; Yokoyama, M1
Antoniades, C; Antonopoulos, AS; Bakogiannis, C; Bendall, J; Casadei, B; Channon, KM; Demosthenous, M; Guzik, TJ; Hale, A; Leeson, P; Marinou, K; Paschalis, A; Psarros, C; Stefanadis, C; Tousoulis, D; Triantafyllou, C; Zhang, MH1
Holowatz, LA; Kenney, WL1
Geddawy, A; Imamura, T; Iwasaki, H; Masada, M; Okamura, T; Shimosato, T; Shinozaki, K; Shintaku, H; Tawa, M; Yoshida, Y1

Trials

3 trial(s) available for pyrroles and sapropterin

ArticleYear
Plasma tetrahydrobiopterin/dihydrobiopterin ratio: a possible marker of endothelial dysfunction.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:5

    Topics: Aged; Atorvastatin; Biomarkers; Biopterins; Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Predictive Value of Tests; Pyrroles; Risk Assessment; Risk Factors; Ultrasonography; Vasodilation

2009
Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
    Circulation, 2011, Jul-19, Volume: 124, Issue:3

    Topics: Aged; Atorvastatin; Biological Availability; Biopterins; Coronary Artery Bypass; Coronary Artery Disease; Coronary Vessels; Double-Blind Method; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Coupling; Oxygen; Pyrroles; Superoxides

2011
Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function in hypercholesterolaemic humans.
    The Journal of physiology, 2011, Oct-01, Volume: 589, Issue:Pt 19

    Topics: Anticholesteremic Agents; Arginase; Arginine; Atorvastatin; Biopterins; Cholesterol; Female; Heating; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Microcirculation; Microdialysis; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrroles; Regional Blood Flow; Skin; Vasodilation

2011

Other Studies

4 other study(ies) available for pyrroles and sapropterin

ArticleYear
The effect of high glucose on NO and O2- through endothelial GTPCH1 and NADPH oxidase.
    Life sciences, 2004, Nov-12, Volume: 75, Issue:26

    Topics: Animals; Atorvastatin; Biopterins; Blotting, Western; Cattle; Endothelial Cells; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glucose; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric

2004
Inefficient spin trapping of superoxide in the presence of nitric-oxide: implications for studies on nitric-oxide synthase uncoupling.
    Free radical biology & medicine, 2006, Aug-01, Volume: 41, Issue:3

    Topics: Animals; Arginine; Biopterins; Cell Line; Electrochemistry; Electron Spin Resonance Spectroscopy; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Binding; Pyrroles; Rats; Spin Trapping; Spodoptera; Superoxide Dismutase; Superoxides

2006
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
    Atherosclerosis, 2008, Volume: 198, Issue:1

    Topics: Animals; Atorvastatin; Biopterins; Body Weight; Cell Adhesion Molecules; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Male; Microfilament Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pyrroles; Rats; Rats, Wistar; Stem Cells; Tetrahydrofolate Dehydrogenase; Vasodilation

2008
Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:1

    Topics: Amlodipine; Animals; Atorvastatin; Biopterins; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Fructose; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxides; Vasoconstriction; Vasodilation

2014