Page last updated: 2024-08-18

pyrroles and ro 24-7429

pyrroles has been researched along with ro 24-7429 in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Palca, J	1
Connell, EV; Hsu, MC; Richman, DD	1
Flexner, C; Ginsberg, R; Hamzeh, FM; Haubrich, RH; Hirsch, M; Lederman, MM; Lietman, P; Pettinelli, CP; Richman, DD; Spector, SA	1
Guatelli, J; Kraus, G; Luznik, L; Richman, D; Wong-Staal, F	1
Crowe, SM; Dunne, AL; Mills, J; Siregar, H	1
Li, CJ; Pardee, AB; Wang, C	1
Ahlers, CM; Biswas, DK; Dezube, BJ; Pardee, AB	1
Braddock, M; Cannon, P; Kingsman, AJ; Kingsman, SM; Muckenthaler, M	1
Dhingra, U; Earley, JV; Holly, M; Hsu, MC; Keith, D; Nalin, CM; Potash, MJ; Richou, AR; Schutt, AD; Tam, SY	1
Bechtel, L; D'Aquila, RT; Hirsch, MS; Hsiung, GD; Kaplan, JC; Margalith, M; Medina, DJ; Skolnik, PR; Smith, BR; Wang, MZ	1
Coffen, DL; Maehr, H; Zenchoff, G	1
Lederman, MM; Patki, AH	1
Biswas, DK; Pardee, AB; Tius, MA; Zhuo, J	1
Debatin, KM; Ehret, A; Frank, R; Heeney, JL; Herr, I; Krammer, PH; Westendorp, MO	1
Baba, M; Hashimoto, K; Kira, T; Okamoto, T; Shigeta, S	1
Biswas, DK; LaVecchio, J; Marasco, WA; Mhashilkar, AM; Pardee, AB	1
Acel, A; Chandok, R; Colby-Germinario, SP; Davison, K; Faust, E; Germinario, RJ; Kleiman, L; Mak, J; Wainberg, MA	1

Trials

2 trial(s) available for pyrroles and ro 24-7429

Article	Year
New AIDS drug poised to move into development. Science (New York, N.Y.), 1991, Dec-20, Volume: 254, Issue:5039 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Benzodiazepines; Drug Evaluation; Drug Industry; Gene Products, tat; HIV; Humans; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; United States	1991
A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team. The Journal of infectious diseases, 1995, Volume: 172, Issue:5 Topics: Adult; Antiviral Agents; Benzodiazepines; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Female; Gene Products, tat; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Zidovudine	1995

Article

Year

New AIDS drug poised to move into development.

Science (New York, N.Y.), 1991, Dec-20, Volume: 254, Issue:5039

Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Benzodiazepines; Drug Evaluation; Drug Industry; Gene Products, tat; HIV; Humans; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; United States

1991

A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team.

The Journal of infectious diseases, 1995, Volume: 172, Issue:5

Topics: Adult; Antiviral Agents; Benzodiazepines; CD4 Lymphocyte Count; Didanosine; Dose-Response Relationship, Drug; Female; Gene Products, tat; HIV Core Protein p24; HIV Infections; Humans; Male; Middle Aged; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Zidovudine

1995

Other Studies

17 other study(ies) available for pyrroles and ro 24-7429

Article	Year
Turnabout on AIDS drug. Science (New York, N.Y.), 1992, Jan-10, Volume: 255, Issue:5041 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Benzodiazepines; Gene Products, tat; Genes, tat; HIV; Humans; Pyrroles; tat Gene Products, Human Immunodeficiency Virus	1992
Promising AIDS drug looking for a sponsor. Science (New York, N.Y.), 1991, Jul-19, Volume: 253, Issue:5017 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Benzodiazepines; Drug Industry; Humans; National Institutes of Health (U.S.); Pyrroles; Research Support as Topic; United States	1991
Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2 Topics: Antiviral Agents; Benzodiazepines; Didanosine; Drug Synergism; Gene Products, tat; HeLa Cells; HIV; HIV Protease Inhibitors; Humans; Isoquinolines; Nevirapine; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; tat Gene Products, Human Immunodeficiency Virus; Zalcitabine; Zidovudine	1994
Tat-independent replication of human immunodeficiency viruses. The Journal of clinical investigation, 1995, Volume: 95, Issue:1 Topics: Benzodiazepines; Cell Line; Defective Viruses; Drug Antagonism; Gene Products, tat; HIV; HIV-1; HIV-2; Humans; Monocytes; Pyrroles; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha; Virus Replication	1995
HIV replication in chronically infected macrophages is not inhibited by the Tat inhibitors Ro-5-3335 and Ro-24-7429. Journal of leukocyte biology, 1994, Volume: 56, Issue:3 Topics: Antigens, Viral; Antiviral Agents; Benzodiazepines; Benzodiazepinones; Cells, Cultured; HIV-1; Humans; Macrophages; Pyrroles; Virus Replication	1994
Camptothecin inhibits Tat-mediated transactivation of type 1 human immunodeficiency virus. The Journal of biological chemistry, 1994, Mar-11, Volume: 269, Issue:10 Topics: Base Sequence; Benzodiazepines; Camptothecin; Cell Line; Gene Expression Regulation, Viral; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Pyrroles; Regulatory Sequences, Nucleic Acid; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation	1994
Cooperative inhibition of NF-kappa B and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat. Proceedings of the National Academy of Sciences of the United States of America, 1993, Dec-01, Volume: 90, Issue:23 Topics: Antiviral Agents; Benzodiazepines; Cell Line; Drug Synergism; Gene Expression Regulation, Viral; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; NF-kappa B; Pentoxifylline; Pyrroles; tat Gene Products, Human Immunodeficiency Virus	1993
Inhibition of human immunodeficiency virus type 1 Tat-dependent activation of translation in Xenopus oocytes by the benzodiazepine Ro24-7429 requires trans-activation response element loop sequences. Journal of virology, 1994, Volume: 68, Issue:1 Topics: Animals; Antiviral Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Gene Expression Regulation, Viral; Gene Products, tat; HIV-1; Humans; Models, Genetic; Molecular Sequence Data; Nucleic Acid Conformation; Oocytes; Protein Biosynthesis; Pyrroles; Regulatory Sequences, Nucleic Acid; RNA, Viral; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Tumor Cells, Cultured; Virus Replication; Xenopus	1994
Inhibition of type 1 human immunodeficiency virus replication by a tat antagonist to which the virus remains sensitive after prolonged exposure in vitro. Proceedings of the National Academy of Sciences of the United States of America, 1993, Jul-15, Volume: 90, Issue:14 Topics: Alkaline Phosphatase; Animals; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; Lymphocytes; Macrophages; Promoter Regions, Genetic; Pyrroles; Serial Passage; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transfection; Up-Regulation; Virus Replication	1993
Interactions between HIV-1 and cytomegalovirus in human osteosarcoma cells carrying both viruses. AIDS research and human retroviruses, 1993, Volume: 9, Issue:6 Topics: Antiviral Agents; Benzodiazepines; Cytomegalovirus; Drug Resistance, Microbial; Gene Products, env; Gene Products, tat; HIV-1; Humans; Mycophenolic Acid; Osteosarcoma; Proviruses; Pyrroles; Sequence Deletion; Superinfection; tat Gene Products, Human Immunodeficiency Virus; Tumor Cells, Cultured; Virus Replication	1993
An alternate synthesis of the Tat-antagonist 7-chloro-N-methyl-5-(1H-pyrrol-2-yl)-3H-1,4-benzodiazepin-2-amine. Bioorganic & medicinal chemistry, 1995, Volume: 3, Issue:4 Topics: Benzodiazepines; Gene Products, tat; HIV-1; Humans; Magnetic Resonance Spectroscopy; Methylamines; Models, Molecular; Molecular Structure; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Virus Replication	1995
HIV-1 Tat protein and its inhibitor Ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors. Cellular immunology, 1996, Apr-10, Volume: 169, Issue:1 Topics: Antiviral Agents; Apoptosis; Benzodiazepines; Cell Division; Cells, Cultured; Gene Products, tat; HIV-1; Humans; Leukocytes, Mononuclear; Pyrroles; tat Gene Products, Human Immunodeficiency Virus	1996
Canventol inhibits HIV-1 replication by Tat-induced Tar-independent mechanism. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Jun-01, Volume: 12, Issue:2 Topics: Antiviral Agents; Base Sequence; Benzodiazepines; Cell Line; Cyclohexanols; Down-Regulation; Drug Synergism; Gene Products, tat; HIV Long Terminal Repeat; HIV-1; Humans; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Tumor Necrosis Factor-alpha; Virus Replication	1996
Resistance of chimpanzee T cells to human immunodeficiency virus type 1 Tat-enhanced oxidative stress and apoptosis. Journal of virology, 1996, Volume: 70, Issue:9 Topics: Acquired Immunodeficiency Syndrome; Animals; Antigens, Surface; Antiviral Agents; Apoptosis; Benzodiazepines; Cell Death; Cell Line; Disease Susceptibility; Fas Ligand Protein; Gene Products, tat; Humans; Immunoglobulin M; Lymphocyte Activation; Membrane Glycoproteins; Oxidative Stress; Pan troglodytes; Pyrroles; RNA, Messenger; Species Specificity; Superoxide Dismutase; T-Lymphocytes; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Tumor Cells, Cultured	1996
2-Glycineamide-5-chlorophenyl 2-pyrryl ketone, a non-benzodiazepin Tat antagonist, is effective against acute and chronic HIV-1 infections in vitro. Antiviral research, 1996, Volume: 32, Issue:2 Topics: Anti-HIV Agents; Benzodiazepines; Benzodiazepinones; Cell Line; Gene Products, tat; HIV-1; Humans; Molecular Structure; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Virus Replication	1996
Inhibition of human immunodeficiency virus type 1 replication in vitro by a novel combination of anti-Tat single-chain intrabodies and NF-kappa B antagonists. Journal of virology, 1997, Volume: 71, Issue:9 Topics: Anti-HIV Agents; Benzodiazepines; Carbazoles; CD4-Positive T-Lymphocytes; Cell Line; Gene Products, tat; HIV Antibodies; HIV Long Terminal Repeat; HIV-1; Humans; Indoles; Jurkat Cells; Leukocytes, Mononuclear; NF-kappa B; Pentoxifylline; Phytohemagglutinins; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; Time Factors; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha; Virus Replication	1997
Effect of insulin-like growth factor I on HIV type 1 long terminal repeat-driven chloramphenicol acetyltransferase expression. AIDS research and human retroviruses, 1999, Jun-10, Volume: 15, Issue:9 Topics: Animals; Anti-HIV Agents; Benzodiazepines; Chloramphenicol O-Acetyltransferase; COS Cells; Gene Expression Regulation, Viral; Gene Products, tat; Genes, Reporter; HIV Long Terminal Repeat; HIV Reverse Transcriptase; HIV-1; Humans; Insulin-Like Growth Factor I; Interleukin-4; Jurkat Cells; Parathyroid Hormone-Related Protein; Proteins; Pyrroles; tat Gene Products, Human Immunodeficiency Virus; U937 Cells	1999