Page last updated: 2024-08-18

pyrroles and prodigiosin

pyrroles has been researched along with prodigiosin in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (46.25)	18.7374
1990's	0 (0.00)	18.2507
2000's	22 (27.50)	29.6817
2010's	17 (21.25)	24.3611
2020's	4 (5.00)	2.80

Authors

Authors	Studies
Cho, LK; Lowe, JA; Maguire, RB; Tsang, JC	1
Bocker, H; Haupt, I	1
Boyanoff, A; Dimitrov, DP; Todorov, TA	1
Bascur de Medina, L; Hearn, WR; Tanaka, WK	1
Qadri, SM; Williams, RP	1
Hussain Qadri, SM; Williams, RP	1
Alden, JR; Deol, BS; Robertson, AV; Still, JL; Winkler, J	1
Munoz, EF; Silverman, MP	1
Guze, LB; Hubert, EG; Kalmanson, GM; Montgomerie, JZ; Potter, CS	1
Beaulieu, T; Jago, MV; Kovacs, K; Tuchweber, B	1
Cruz-Camarillo, R; Sánchez-Zúñiga, AA	1
Reisner, GS	1
Goldschmidt, MC; Williams, RP	1
Elson, MK; Hearn, WR; Medina-Castro, J; Williams, RH	1
Bartlett, WT; Neff, RD; O'Donovan, GA	1
Gott, CL; Qadri, SM; Scott, RH; Williams, RP	1
Gott, CL; Qadri, SM; Williams, RP	1
Andreeva, PG; Givental', NI; Kushnareva, TO	1
Hanks, AR; Mroz, E	1
Neff, RD; O'Donovan, GA; Webb, PS	1
Bermingham, MA; Deol, BS; Still, JL	1
Ivanova, TI; Kekalo, LA; Neĭko, EM; Olgina, FP	1
Givental', NI	1
Gerber, NN	3
Eĭdel'shtein, SI; Ermol'eva, ZV; Prokhorova, II; Taranenko, AL; Vaĭsberg, GE	1
Goldschmidt, ME; Mukherjee, PP; Williams, RP	1
Danielian, EE	1
Balitskiĭ, KP; Struk, VI	1
Keith, DD; Rodgers, GC; Wasserman, HH	1
Keith, DD; Nadelson, J; Wasserman, HH	1
Roth, MM	1
Ding, MJ; Williams, RP	1
Bargiotti, A; Carlini, O; Colotta, F; D'Alessio, R; Ferrari, M; Gnocchi, P; Isetta, A; Mongelli, N; Motta, P; Rossi, A; Rossi, M; Tibolla, M; Vanotti, E	1
Bibb, MJ; Cerdeño, AM; Challis, GL	1
Kucera, GL; Lindquist, N; Manderville, RA; Melvin, MS; Rich, CC; Saluta, GR; Wooton, KE	1
Behbod, F; Erwin-Cohen, RA; Kahan, BD; Kirken, RA; Nagy, ZS; Qu, X; Stepkowski, SM; Tejpal, N; Wang, ME	1
Fürstner, A; Grabowski, EJ	1
Burkart, MD; Thomas, MG; Walsh, CT	1
Calcutt, MW; Manderville, RA; Melvin, MS; Noftle, RE	1
Chander, R; Pandey, R; Sainis, KB	2
Fürstner, A	1
SANTER, UV; VOGEL, HJ	1
PETERSON, GE; SIDDIQUI, MA	1
GOLDSCHMIDT, ME; GOTT, CL; WILLIAMS, RP	1
Fürstner, A; Prinz, H; Reinecke, K; Waldmann, H	1
Kahan, BD; Podder, H	1
Fürstner, A; Peters, H; Radkowski, K	1
Ahmed, RA; Goldet, G; Leeper, FJ; Salmond, GP; Simonsen, HT; Slater, H; Williamson, NR; Woodley, L	1
Dudley, GB; Salamone, SG	1
Baldino, CM; Ng, SC; Parr, J; Wasserman, HH; Wilson, CJ; Yohannes, D	1
Dorrestein, PC; Garneau-Tsodikova, S; Kelleher, NL; Walsh, CT	1
Chander, R; Deorukhkar, AA; Pandey, R; Sainis, KB	1
Chander, R; Deorukhkar, AA; Ghosh, SB; Sainis, KB	1
Alhamadsheh, MM; Challis, GL; Corre, C; Haynes, SW; Mo, S; Reynolds, KA; Song, L; Stanley, AE; Sydor, PK	1
Hayakawa, Y; Kawasaki, T; Sakurai, F	1
Hayakawa, Y; Kawasaki, T; Nagatsuka, SY; Sakurai, F	1
Pérez-Tomás, R; Viñas, M	1
Choi, JM; Kang, SJ; Kim, J; Kim, YS; Lee, JS; Lee, MH; Oh, TK; Park, S; Ryu, S; Yoon, JH	1
Díaz de Greñu, B; Espona, M; Iglesias Hernández, P; Light, ME; Pérez-Tomás, R; Quesada, R; Quiñonero, D; Torroba, T	1
Espona-Fiedler, M; Gao, T; Guallar, V; Hosseini, A; Lizcano, JM; Pérez-Tomás, R; Quesada, R; Soto-Cerrato, V	1
Berman, JN; Colpitts, J; Corkery, DP; Dellaire, G; Forrester, AM; McFarland, SA; Smithen, DA; Thompson, A	1
Florova, G; Gupta, S; Kancharla, P; Lu, W; Reynolds, KA; Salem, SM	1
Gao, Y; Han, N; He, J; Lou, X; Ran, T; Tang, L; Wang, W; Xu, D	1
Astashkin, AV; Chang, TM; Sinharay, S; Tomat, E	1
Challis, GL; Haynes, SW; Withall, DM	1
Antoine, R; Aronssohn, N; Drink, E; Dugourd, P; Dumont, E; Loison, C	1
Bharti, D; Ramana, CV; Ramaprasad, EVV; Sasikala, C	1
Hayakawa, Y; Izawa, M; Kawasaki, T; Kimata, S	1
Ran, T; Tong, H; Wang, W; Wei, Q; Xu, D; Zhang, F	1
Kancharla, P; Lu, W; Reynolds, KA	1
Baidoo, EEK; Chan, LJG; de Rond, T; Eigl, I; Goyal, G; Hillson, NJ; Johnson, RE; Keasling, JD; Petzold, CJ; Sarpong, R; Stow, P	1
Alkhalaf, LM; Challis, GL; de Los Santos, ELC; Perry, C	1
Chang, YK; Chen, WC; Soo, PC; Tsai, MJ; Tsai, SL; Wang, LF; Wei, YH	1
Deichert, JA; deKemp, EM; Picott, KJ; Ross, AC; Snieckus, V	1
Caffrey, CR; Company, AH; Debnath, A; DeRisi, J; Ehrenkaufer, G; Gisselberg, J; Huston, CD; Kangussu-Marcolino, MM; Li, P; Monti, L; Moser, MS; Singh, U; Stebbins, EE; Wang, B; Wang, SC; White, CV; Yeh, E	1
Anishetty, S; Pennathur, G; Ravindran, A	1
Carreira-Barral, I; Fiore, M; García-Valverde, M; Moran, O	1

Reviews

3 review(s) available for pyrroles and prodigiosin

Article	Year
Chemistry and biology of roseophilin and the prodigiosin alkaloids: a survey of the last 2500 years. Angewandte Chemie (International ed. in English), 2003, Aug-11, Volume: 42, Issue:31 Topics: Alkaloids; Animals; Anti-Infective Agents; Heterocyclic Compounds, 3-Ring; History, 16th Century; History, 19th Century; History, 20th Century; History, Ancient; History, Medieval; Humans; Molecular Structure; Prodigiosin; Pyrroles	2003
New insights on the antitumoral properties of prodiginines. Current medicinal chemistry, 2010, Volume: 17, Issue:21 Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; DNA Damage; Humans; Indoles; Neoplasms; Prodigiosin; Pyrroles; Serratia; Signal Transduction	2010
Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis. Natural product reports, 2018, 07-18, Volume: 35, Issue:7 Topics: Biological Products; Cyclization; Electron Transport Complex III; Heme; Heterocyclic Compounds, 3-Ring; Hydroxylation; Oxygenases; Prodigiosin; Pyrroles; Pyrrolnitrin; Spiro Compounds	2018

Other Studies

77 other study(ies) available for pyrroles and prodigiosin

Article	Year
Relationship of prodigiosin condensing enzyme activity to the biosynthesis of prodigiosin and its precursors in Serratia marcescens. Experientia, 1987, Apr-15, Volume: 43, Issue:4 Topics: Cell Division; DNA, Recombinant; Hydro-Lyases; Kinetics; Mutation; Prodigiosin; Pyrroles; Serratia marcescens; Streptomyces	1987
[A selective strain of Streptomyces albus var. metamycinus JA 3626 (Bradler a. Thrum) producing DL-alanine and a prodigiosin-like pigment]. Zeitschrift fur allgemeine Mikrobiologie, 1969, Volume: 9, Issue:1 Topics: Alanine; Anti-Bacterial Agents; Chromatography, Paper; Culture Media; Dactinomycin; Fermentation; Genetics, Microbial; Microscopy, Electron; Mutation; Paromomycin; Pigments, Biological; Prodigiosin; Pyrroles; Spores; Streptomyces	1969
A study of the association of prodigiosin, isolated from Serratia marcescens. Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1970, Volume: 25, Issue:1 Topics: Acetone; Anti-Bacterial Agents; Pigments, Biological; Polymers; Prodigiosin; Pyrroles; Serratia marcescens; Solutions; Spectrophotometry	1970
Labeling patterns in prodigiosin biosynthesis. Biochemical and biophysical research communications, 1972, Jan-31, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; Genetics, Microbial; Glycine; Maleimides; Methionine; Mutation; Oxidation-Reduction; Pigments, Biological; Prodigiosin; Proline; Pyrroles; Serratia marcescens	1972
Induction of prodigiosin biosynthesis after shift-down in temperature of nonproliferating cells of Serratia marcescens. Applied microbiology, 1972, Volume: 23, Issue:4 Topics: Amino Acids; Anti-Bacterial Agents; Bacteriological Techniques; Culture Media; Methionine; Pigments, Biological; Prodigiosin; Proline; Pyrroles; Serratia marcescens; Spectrophotometry; Stereoisomerism; Temperature	1972
Biosynthesis of the tripyrrole bacterial pigment, prodigiosin, by nonproliferating cells of Serratia marcescens. Texas reports on biology and medicine, 1972,Spring, Volume: 30, Issue:1 Topics: Amino Acids; Anti-Bacterial Agents; Carbon Isotopes; Cell Count; Chloramphenicol; Chloroquine; Cycloheximide; Dactinomycin; Fluorouracil; Kinetics; Mitomycins; Pigments, Biological; Prodigiosin; Proteins; Puromycin; Pyrroles; Serratia marcescens; Streptomycin; Temperature; Tryptophan	1972
The isolation and characterization of monopyrroles from Serratia marcescens. Biochemical and biophysical research communications, 1972, Jun-28, Volume: 47, Issue:6 Topics: Chromatography, Gas; Chromatography, Thin Layer; Ethyl Ethers; Genetics, Microbial; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutation; Prodigiosin; Pyrroles; Serratia marcescens; Solubility	1972
Effect of iron and salt on prodigiosin synthesis in Serratia marcescens. Journal of bacteriology, 1973, Volume: 114, Issue:3 Topics: Aldehydes; Culture Media; Iron; Mutation; Pigmentation; Potassium Chloride; Prodigiosin; Pyrroles; Serratia marcescens; Sodium Chloride; Spectrophotometry, Atomic; Sulfates	1973
Defects in prodigiosin formation by L-forms of Serratia marcescens. Journal of bacteriology, 1973, Volume: 116, Issue:3 Topics: Cell Count; Filtration; L Forms; Mutation; Prodigiosin; Protein Precursors; Pyrroles; Serratia marcescens	1973
Effect of steroidal and nonsteroidal microsomal enzyme inducers on the hepatotoxicity of pyrrolizidine alkaloids in rats. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:2 Topics: Animals; Enzyme Induction; Ethylestrenol; Female; Hepatectomy; Kidney; Liver; Lung; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Pregnenolone Carbonitrile; Prodigiosin; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Spironolactone	1974
Complex protein-prodigiosin in Serratia marcescens. Nature, 1968, May-11, Volume: 218, Issue:5141 Topics: Absorption; Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Dextrans; Pigments, Biological; Prodigiosin; Protein Binding; Pyrroles; Serratia marcescens; Spectrum Analysis	1968
Prodigiosin and the metabolism of free amino compounds in Serratia marcescens as a function of iron, manganese, and aging. Canadian journal of microbiology, 1969, Volume: 15, Issue:5 Topics: Amino Acids; Amino Alcohols; Anti-Bacterial Agents; Iron; Manganese; Pigments, Biological; Prodigiosin; Pyrroles; Serratia marcescens	1969
Thiamine-induced formation of the monopyrrole moiety of prodigiosin. Journal of bacteriology, 1968, Volume: 96, Issue:3 Topics: Anti-Bacterial Agents; Culture Media; Glycerol; Mutation; Pigments, Biological; Prodigiosin; Pyrimidines; Pyrroles; Serratia marcescens; Thiamine; Thiazoles	1968
Prodigiosene [5-(2-pyrryl)-2,2-'-dipyrrylmethene] and some substituted prodigiosenes. The Journal of organic chemistry, 1970, Volume: 35, Issue:1 Topics: Anti-Bacterial Agents; Pigments, Biological; Prodigiosin; Pyrroles; Serratia marcescens; Spectrum Analysis	1970
Effect of gamma radiation on Serratia marcescens. Studies on the radiosensitivity of prodigiosin production. Radiation research, 1970, Volume: 43, Issue:1 Topics: Anti-Bacterial Agents; Clone Cells; Cobalt Isotopes; Mutation; Pigments, Biological; Prodigiosin; Pyrroles; Radiation Effects; Serratia marcescens	1970
Influence of temperature of incubation and type of growth medium on pigmentation in Serratia marcescens. Journal of bacteriology, 1971, Volume: 106, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacteriological Techniques; Caseins; Cell Division; Chloramphenicol; Culture Media; Hot Temperature; Hydrogen-Ion Concentration; Oxygen; Pigments, Biological; Prodigiosin; Protein Hydrolysates; Pyrroles; Saccharomyces; Serratia marcescens; Spectrophotometry; Temperature; Time Factors	1971
Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids. Journal of bacteriology, 1971, Volume: 106, Issue:2 Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Bacteriological Techniques; Caseins; Culture Media; Filtration; Glutamates; Ornithine; Pigments, Biological; Prodigiosin; Proline; Protein Hydrolysates; Pyrroles; Serine; Serratia marcescens; Stereoisomerism; Temperature	1971
[Use of polysaccharide prodigiozan in the complex therapy of chronic and residual brucellosis]. Antibiotiki, 1971, Volume: 16, Issue:6 Topics: Adult; Anti-Bacterial Agents; Ascorbic Acid; Brucellosis; Chronic Disease; Drug Hypersensitivity; Female; Humans; Immunotherapy; Male; Middle Aged; Muramidase; Oleandomycin; Phagocytosis; Physical Therapy Modalities; Pigments, Biological; Prodigiosin; Pyrroles; Serratia marcescens; Stimulation, Chemical; Tetracycline; Vitamins	1971
Ultraviolet radiation sensitivity of white mutants and red wild-type Serratia marcescens. Radiation research, 1971, Volume: 48, Issue:2 Topics: Acridines; Animals; Anti-Bacterial Agents; Caffeine; Cell Survival; Culture Media; Mutation; Pigments, Biological; Prodigiosin; Pyrroles; Radiation Effects; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Serratia marcescens; Species Specificity; Ultraviolet Rays	1971
Effect of gamma radiation on Serratia marcescens. Comparison of the radiosensitivity of pigmented and nonpigmented cells. Radiation research, 1971, Volume: 48, Issue:1 Topics: Anti-Bacterial Agents; Cell Survival; Chemical Phenomena; Chemistry; Cobalt Isotopes; Mutation; Pigments, Biological; Prodigiosin; Pyrroles; Radiation Effects; Radiation-Sensitizing Agents; Serratia marcescens; Temperature	1971
The relationship between prodigiosin biosynthesis and cyclic depsipeptides in Serratia marcescens. Journal of general microbiology, 1971, Volume: 67, Issue:3 Topics: Anti-Bacterial Agents; Culture Media; Lipid Metabolism; Mutation; Peptide Biosynthesis; Peptides, Cyclic; Pigments, Biological; Prodigiosin; Pyrroles; Serine; Serratia marcescens; Temperature	1971
[Indices of outer respiration in complex therapy of chronic pneumonia using prodigiosin]. Antibiotiki, 1972, Volume: 17, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Humans; Middle Aged; Pigments, Biological; Pneumonia; Prodigiosin; Pyrroles; Respiration	1972
[Stimulation of normal and immune antibody formation by the lipopolysaccharide prodigiosan]. Antibiotiki, 1972, Volume: 17, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antibody Formation; Antibody-Producing Cells; Female; Lipopolysaccharides; Male; Mice; Pigments, Biological; Prodigiosin; Pyrroles; Spleen; Stimulation, Chemical	1972
Prodigiosin-like pigments from Actinomadura (Nocardia) pelletieri. The Journal of antibiotics, 1971, Volume: 24, Issue:9 Topics: Anti-Bacterial Agents; Bacteria; Fungi; Mass Spectrometry; Microbial Sensitivity Tests; Nocardia; Pigments, Biological; Prodigiosin; Pyrroles	1971
[Effect of prodigiosin aerosol inhalation on immunobiological reactivity in experiments]. Antibiotiki, 1971, Volume: 16, Issue:12 Topics: Aerosols; Animals; Anti-Bacterial Agents; Immunity; Injections, Intramuscular; Leukocytes; Pigments, Biological; Prodigiosin; Pyrroles; Rabbits; Respiratory System	1971
Enzymic formation of prodigiosin analog by a cell-free preparation from Serratia marcescens. Biochimica et biophysica acta, 1967, Feb-07, Volume: 136, Issue:1 Topics: Adenosine Triphosphate; Chloromercuribenzoates; Enzymes; Ethylmaleimide; Iodoacetates; Magnesium; Prodigiosin; Pyrroles; Serratia marcescens	1967
A novel, cyclic, tripyrrole pigment from Actinomadura (nocardia) madurae. Tetrahedron letters, 1970, Issue:11 Topics: Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Nocardia; Pigments, Biological; Prodigiosin; Pyrroles; Spectrum Analysis	1970
[Prodigiosan in the complex treatment of eczema, neurodermatitis and prurigo in children]. Vestnik dermatologii i venerologii, 1970, Volume: 44, Issue:12 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Eczema; Humans; Infant; Neurodermatitis; Pigments, Biological; Prodigiosin; Prurigo; Pyrroles	1970
[Activation of protective reactions of the organism in malignant growths]. Zhurnal eksperimental'noi i klinicheskoi meditsiny, 1968, Volume: 8, Issue:2 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzimidazoles; Drug Synergism; Immunity, Active; Neoplasms, Experimental; Parasympatholytics; Pigments, Biological; Prodigiosin; Pyrroles; Rabbits; Rats; Zymosan	1968
Metacycloprodigiosin, a tripyrrole pigment from Streptomyces longisporus ruber. Journal of the American Chemical Society, 1969, Feb-26, Volume: 91, Issue:5 Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Pigments, Biological; Prodigiosin; Pyrroles; Streptomyces	1969
The synthesis of metacycloprodigiosin. Journal of the American Chemical Society, 1969, Feb-26, Volume: 91, Issue:5 Topics: Anti-Bacterial Agents; Pigments, Biological; Prodigiosin; Pyrroles; Streptomyces	1969
Prodigiosin-like pigments from Actinomadura (Nocardia) pelletieri and Actinomadura madurae. Applied microbiology, 1969, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Chromatography; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Nocardia; Pigments, Biological; Prodigiosin; Pyrroles; Spectrum Analysis	1969
The photosensitizing ability of prodigiosin. Photochemistry and photobiology, 1967, Volume: 6, Issue:12 Topics: Anti-Bacterial Agents; Light; Pigments, Biological; Prodigiosin; Pyrroles	1967
Biosynthesis of prodigiosin by white strains of Serratia marcescens isolated from patients. Journal of clinical microbiology, 1983, Volume: 17, Issue:3 Topics: Adult; Humans; Middle Aged; Prodigiosin; Pyrroles; Serratia marcescens	1983
Synthesis and immunosuppressive activity of novel prodigiosin derivatives. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Animals; Cell Survival; Female; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; In Vitro Techniques; Lymphocytes; Mice; Mice, Inbred C57BL; Prodigiosin; Pyrroles; Spleen; Structure-Activity Relationship; Tumor Cells, Cultured	2000
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes. Chemistry & biology, 2001, Volume: 8, Issue:8 Topics: Gene Deletion; Gene Order; Genes, Bacterial; Multienzyme Complexes; Multigene Family; Physical Chromosome Mapping; Pigments, Biological; Point Mutation; Prodigiosin; Protein Processing, Post-Translational; Pyrroles; Streptomyces	2001
Copper-nuclease efficiency correlates with cytotoxicity for the 4-methoxypyrrolic natural products. Journal of inorganic biochemistry, 2001, Dec-01, Volume: 87, Issue:3 Topics: Apoptosis; Biological Products; Copper; Deoxyribonucleases; DNA; DNA Damage; HL-60 Cells; Humans; Molecular Structure; Prodigiosin; Pyrroles; Spectrometry, Fluorescence	2001
Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin. Blood, 2002, Jan-15, Volume: 99, Issue:2 Topics: Administration, Oral; Animals; Cell Line; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Inhibitors; Graft Survival; Heart Transplantation; Humans; Immunosuppressive Agents; Interleukins; Janus Kinase 2; Janus Kinase 3; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Signaling System; Milk Proteins; Phosphorylation; Prodigiosin; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Rats; Rats, Inbred BUF; Rats, Inbred WF; Sirolimus; STAT5 Transcription Factor; T-Lymphocytes; Trans-Activators	2002
Studies on DNA cleavage by cytotoxic pyrrole alkaloids reveal the distinctly different behavior of roseophilin and prodigiosin derivatives. Chembiochem : a European journal of chemical biology, 2001, Sep-03, Volume: 2, Issue:9 Topics: Alkaloids; Anti-Bacterial Agents; DNA; Electrophoresis, Agar Gel; Heterocyclic Compounds, 3-Ring; Prodigiosin; Pyrroles; Streptomyces	2001
Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin and pyoluteorin biosynthesis. Chemistry & biology, 2002, Volume: 9, Issue:2 Topics: Amino Acyl-tRNA Synthetases; Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Catalysis; Escherichia coli; Genes, Bacterial; Multigene Family; Phenols; Prodigiosin; Proline; Protein Structure, Tertiary; Pseudomonas fluorescens; Pyrroles; Streptomyces; Substrate Specificity	2002
Influence of the a-ring on the redox and nuclease properties of the prodigiosins: importance of the bipyrrole moiety in oxidative DNA cleavage. Chemical research in toxicology, 2002, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; Copper; Electrochemistry; Endodeoxyribonucleases; Oxidation-Reduction; Prodigiosin; Pyrroles; Structure-Activity Relationship	2002
A novel prodigiosin-like immunosuppressant from an alkalophilic Micrococcus sp. International immunopharmacology, 2003, Volume: 3, Issue:2 Topics: Alkenes; Animals; Apoptosis; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Micrococcus; Prodigiosin; Pyrroles; Receptors, Interleukin-2	2003
Prodigiosin synthesis in Serratia marcescens: isolation of a pyrrole-containing precursor. Biochimica et biophysica acta, 1956, Volume: 19, Issue:3 Topics: Anti-Bacterial Agents; Pigments, Biological; Prodigiosin; Pyrroles; Serratia; Serratia marcescens	1956
STREPTOMYCIN AND SYNTROPHIC PRODIGIOSIN SYNTHESIS IN SERRATIA MARCESCENS. Antonie van Leeuwenhoek, 1965, Volume: 31 Topics: Bacteriological Techniques; Metabolism; Mutation; Pigments, Biological; Prodigiosin; Pyrroles; Research; Serratia marcescens; Streptomycin	1965
INHIBITION BY TEMPERATURE OF THE TERMINAL STEP IN BIOSYNTHESIS OF PRODIGIOSIN. Biochemical and biophysical research communications, 1965, Apr-09, Volume: 19 Topics: Chromatography; Enzyme Inhibitors; Metabolism; Pigments, Biological; Prodigiosin; Pyrroles; Research; Serratia marcescens; Temperature	1965
The core structures of roseophilin and the prodigiosin alkaloids define a new class of protein tyrosine phosphatase inhibitors. Chembiochem : a European journal of chemical biology, 2004, Nov-05, Volume: 5, Issue:11 Topics: Alkaloids; Enzyme Inhibitors; Heterocyclic Compounds, 3-Ring; Humans; Molecular Structure; Prodigiosin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Pyrroles	2004
Janus kinase 3: a novel target for selective transplant immunosupression. Expert opinion on therapeutic targets, 2004, Volume: 8, Issue:6 Topics: Amino Acid Sequence; Animals; Drug Evaluation, Preclinical; Graft Rejection; Humans; Immunosuppressive Agents; Interleukin Receptor Common gamma Subunit; Janus Kinase 2; Janus Kinase 3; Lymphocyte Activation; Lymphocytes; Macaca fascicularis; Mannich Bases; Mice; Molecular Sequence Data; Molecular Structure; Phosphorylation; Prodigiosin; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrroles; Rats; Receptors, Cytokine; Receptors, Interleukin-2; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Substrate Specificity	2004
Chasing a phantom by total synthesis: the butylcycloheptylprodigiosin case. Angewandte Chemie (International ed. in English), 2005, Apr-29, Volume: 44, Issue:18 Topics: Esters; Molecular Structure; Phantoms, Imaging; Prodigiosin; Pyrroles	2005
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces. Molecular microbiology, 2005, Volume: 56, Issue:4 Topics: Anti-Bacterial Agents; Molecular Structure; Multigene Family; Mutation; Prodigiosin; Pyrroles; Serratia; Streptomyces coelicolor	2005
A ring-expansion approach to roseophilin. Organic letters, 2005, Sep-29, Volume: 7, Issue:20 Topics: Heterocyclic Compounds, 3-Ring; Ketones; Molecular Structure; Oxidation-Reduction; Prodigiosin; Pyrroles	2005
Indoloprodigiosins from the C-10 bipyrrolic precursor: new antiproliferative prodigiosin analogs. Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3 Topics: Animals; Antineoplastic Agents; Cell Proliferation; Indoles; Molecular Structure; Prodigiosin; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured	2006
Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J. Journal of the American Chemical Society, 2006, Oct-04, Volume: 128, Issue:39 Topics: Carrier Proteins; Escherichia coli; Mass Spectrometry; Phenylpropionates; Prodigiosin; Proline; Pyrroles; Recombinant Proteins; Serratia	2006
A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type. Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:3 Topics: Alkenes; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dactinomycin; Diploidy; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Lymphoma, T-Cell; Mice; Necrosis; Prodigiosin; Pyrroles; Rats; Sarcoma 180; Staurosporine; Tetrazolium Salts; Thiazoles	2008
Identification of a red-pigmented bacterium producing a potent anti-tumor N-alkylated prodigiosin as Serratia marcescens. Research in microbiology, 2007, Volume: 158, Issue:5 Topics: Alkenes; Animals; Antineoplastic Agents; Cats; Cell Line; Cell Survival; DNA, Bacterial; Humans; Mice; Molecular Sequence Data; Phylogeny; Pigments, Biological; Polymerase Chain Reaction; Prodigiosin; Pyrroles; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Serratia marcescens; U937 Cells	2007
Role of interleukin-2 regulated proteins in immunosuppression by the N-alkylated prodigiosin analogue. International immunopharmacology, 2007, Dec-15, Volume: 7, Issue:13 Topics: Alkenes; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; Cell Division; Cyclin D; Cyclins; Dose-Response Relationship, Drug; fas Receptor; Female; Immunosuppressive Agents; Interleukin-2; Lectins, C-Type; Male; Mice; Prodigiosin; Proliferating Cell Nuclear Antigen; Pyrroles; Receptors, Transferrin; Tumor Suppressor Protein p53	2007
Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. Chemistry & biology, 2008, Volume: 15, Issue:2 Topics: Biosynthetic Pathways; Multigene Family; Prodigiosin; Pyrroles; Sequence Deletion; Streptomyces coelicolor	2008
A prodigiosin from the roseophilin producer Streptomyces griseoviridis. Journal of natural products, 2008, Volume: 71, Issue:7 Topics: Heterocyclic Compounds, 3-Ring; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Prodigiosin; Pyrroles; Streptomyces	2008
Prodigiosin biosynthesis gene cluster in the roseophilin producer Streptomyces griseoviridis. The Journal of antibiotics, 2009, Volume: 62, Issue:5 Topics: Anti-Bacterial Agents; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Heterocyclic Compounds, 3-Ring; Molecular Sequence Data; Multigene Family; Open Reading Frames; Plasmids; Prodigiosin; Pyrroles; Streptomyces	2009
Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1. Applied and environmental microbiology, 2011, Volume: 77, Issue:14 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Chromatography, Liquid; DNA, Bacterial; DNA, Ribosomal; Gammaproteobacteria; Genotype; Humans; Indoles; Mass Spectrometry; Melanoma; Molecular Sequence Data; Phenotype; Phylogeny; Pigments, Biological; Prodigiosin; Pyrroles; Republic of Korea; RNA, Bacterial; RNA, Ribosomal, 16S; Seawater	2011
Synthetic prodiginine obatoclax (GX15-070) and related analogues: anion binding, transmembrane transport, and cytotoxicity properties. Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Dec-09, Volume: 17, Issue:50 Topics: Animals; Anions; Antineoplastic Agents; Apoptosis; Biological Transport; Cattle; Cell Line, Tumor; Crystallography, X-Ray; Humans; Indoles; Ion Transport; Ionophores; Liposomes; Lung Neoplasms; Magnetic Resonance Spectroscopy; Prodigiosin; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Tumor Cells, Cultured	2011
Identification of dual mTORC1 and mTORC2 inhibitors in melanoma cells: prodigiosin vs. obatoclax. Biochemical pharmacology, 2012, Feb-15, Volume: 83, Issue:4 Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Indoles; Insulin Receptor Substrate Proteins; Mechanistic Target of Rapamycin Complex 1; Melanoma; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Prodigiosin; Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Transcription Factors	2012
Investigations regarding the utility of prodigiosenes to treat leukemia. Organic & biomolecular chemistry, 2013, Jan-07, Volume: 11, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Leukemia; Molecular Structure; Neoplasms, Experimental; Prodigiosin; Pyrroles; Structure-Activity Relationship; Zebrafish	2013
Elucidation of final steps of the marineosins biosynthetic pathway through identification and characterization of the corresponding gene cluster. Journal of the American Chemical Society, 2014, Mar-26, Volume: 136, Issue:12 Topics: Antimalarials; Cloning, Molecular; Drug Resistance, Multiple; Multigene Family; Oxidation-Reduction; Plasmodium falciparum; Prodigiosin; Pyrroles; Sequence Analysis; Sequence Homology, Nucleic Acid; Spiro Compounds; Streptomyces	2014
Crystal structure of the catalytic domain of PigE: a transaminase involved in the biosynthesis of 2-methyl-3-n-amyl-pyrrole (MAP) from Serratia sp. FS14. Biochemical and biophysical research communications, 2014, Apr-25, Volume: 447, Issue:1 Topics: Catalytic Domain; Crystallography, X-Ray; Models, Molecular; Prodigiosin; Pyrroles; Serratia; Substrate Specificity; Transaminases	2014
Prodigiosin analogue designed for metal coordination: stable zinc and copper pyrrolyldipyrrins. Inorganic chemistry, 2014, Jul-21, Volume: 53, Issue:14 Topics: Copper; Electron Spin Resonance Spectroscopy; Magnetic Resonance Spectroscopy; Models, Molecular; Prodigiosin; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Zinc	2014
Stereochemistry and Mechanism of Undecylprodigiosin Oxidative Carbocyclization to Streptorubin B by the Rieske Oxygenase RedG. Journal of the American Chemical Society, 2015, Jun-24, Volume: 137, Issue:24 Topics: Cyclization; Oxidation-Reduction; Oxygenases; Prodigiosin; Pyrroles; Stereoisomerism; Streptomyces	2015
Optical properties of prodigiosin and obatoclax: action spectroscopy and theoretical calculations. Physical chemistry chemical physics : PCCP, 2015, Oct-21, Volume: 17, Issue:39 Topics: Antineoplastic Agents; Indoles; Isomerism; Mass Spectrometry; Models, Molecular; Molecular Conformation; Prodigiosin; Protons; Pyrroles; Sodium; Spectrophotometry, Ultraviolet	2015
Zooshikella marina sp. nov. a cycloprodigiosin- and prodigiosin-producing marine bacterium isolated from beach sand. International journal of systematic and evolutionary microbiology, 2015, Volume: 65, Issue:12 Topics: Bacterial Typing Techniques; Base Composition; DNA, Bacterial; Fatty Acids; Gammaproteobacteria; India; Indoles; Molecular Sequence Data; Nucleic Acid Hybridization; Phospholipids; Phylogeny; Pigmentation; Prodigiosin; Pyrroles; RNA, Ribosomal, 16S; Seawater; Sequence Analysis, DNA; Ubiquinone	2015
Identification of a prodigiosin cyclization gene in the roseophilin producer and production of a new cyclized prodigiosin in a heterologous host. The Journal of antibiotics, 2017, Volume: 70, Issue:2 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Bacterial; Heterocyclic Compounds, 3-Ring; Humans; Molecular Structure; Multigene Family; Prodigiosin; Pyrroles; Streptomyces coelicolor	2017
Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14. International journal of biological macromolecules, 2017, Volume: 99 Topics: Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Maltose-Binding Proteins; Models, Molecular; Mutation; Prodigiosin; Protein Conformation; Pyrroles; Recombinant Fusion Proteins; Serratia marcescens	2017
MarH, a Bifunctional Enzyme Involved in the Condensation and Hydroxylation Steps of the Marineosin Biosynthetic Pathway. Organic letters, 2017, 03-17, Volume: 19, Issue:6 Topics: Asparaginase; Bacterial Proteins; Biosynthetic Pathways; Catalysis; Cyclization; Hydroxylation; Multigene Family; Prodigiosin; Protein Conformation; Protein Domains; Pyrans; Pyrroles; Pyruvate, Orthophosphate Dikinase; Spiro Compounds; Streptomyces	2017
Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme. Nature chemical biology, 2017, Volume: 13, Issue:11 Topics: Catalysis; Cyclization; Evolution, Molecular; Indoles; Mixed Function Oxygenases; Oxidation-Reduction; Prodigiosin; Pseudoalteromonas; Pyrroles; Streptomyces	2017
Construction and co-cultivation of two mutant strains harboring key precursor genes to produce prodigiosin. Journal of bioscience and bioengineering, 2018, Volume: 126, Issue:6 Topics: Coculture Techniques; Gene Transfer Techniques; Microbiological Techniques; Organisms, Genetically Modified; Prodigiosin; Pyrroles; Serratia marcescens; Transformation, Bacterial	2018
Purification and Kinetic Characterization of the Essential Condensation Enzymes Involved in Prodiginine and Tambjamine Biosynthesis. Chembiochem : a European journal of chemical biology, 2020, 04-01, Volume: 21, Issue:7 Topics: Bacterial Proteins; Biological Products; Kinetics; Multigene Family; Prodigiosin; Pseudoalteromonas; Pyrroles; Recombinant Proteins; Substrate Specificity	2020
Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity. PLoS neglected tropical diseases, 2020, Volume: 14, Issue:3 Topics: Animals; Anisomycin; Antiparasitic Agents; Cell Line; Cell Survival; Drug Repositioning; Fibroblasts; Humans; Indoles; Mice; Parasites; Parasitic Sensitivity Tests; Prodigiosin; Pyrroles; Rats	2020
Molecular dynamics of the membrane interaction and localisation of prodigiosin. Journal of molecular graphics & modelling, 2020, Volume: 98 Topics: Anti-Bacterial Agents; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Prodigiosin; Pyrroles	2020
The different anion transport capability of prodiginine- and tambjamine-like molecules. European journal of pharmacology, 2020, Dec-15, Volume: 889 Topics: Animals; Anion Transport Proteins; Gluconates; Ion Transport; Prodigiosin; Pyrroles; Rats; Rats, Inbred F344	2020