Page last updated: 2024-08-18

pyrroles and porphobilinogen

pyrroles has been researched along with porphobilinogen in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199038 (86.36)18.7374
1990's3 (6.82)18.2507
2000's1 (2.27)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodie, MJ; Goldberg, A; Graham, DJ; McColl, KE; Moore, MR1
Kenner, GW; Rimmer, J; Smith, KM; Unsworth, JF1
Batlle, AM; Stella, AM1
Bogorad, L; Higuchi, M1
Biel, AJ1
Jordan, PM; Woodcock, SC1
Scott, AI; Warren, MJ1
Jordan, PM; Warren, MJ1
de los Santos, C; Frydman, B; Frydman, RB; Rosé, S; Sburlati, A; Valasinas, A1
Kanis, JA1
Müller, G1
Frydman, B; Frydman, RB; Tomaro, ML; Wanschelbaum, A1
Tomokuni, K1
Hatch, T; Lascelles, J1
Davies, RC; Neuberger, A1
Frydman, B; Frydman, RB; Tomaro, ML1
Ogata, M; Tomokuni, K1
Frydman, B; Frydman, RB; Valasinas, A2
Gurne, D; Shemin, D1
Andersen, EM; Awruch, J; Frydman, B; Frydman, RB; Tomaro, ML; Wanschelbaum, A1
Eales, L; Sears, WG1
Adler, AD; George, P; Váradi, V1
Bausch, J; Müller, G1
Doss, M; Marver, HS; Meyer, UA; Rees, AC; Strand, LJ1
Candura, F; Franco, G; Pozzi, U1
Berry, A; Jordan, PM1
ACKNER, B; COOPER, JE; GRAY, CH; KELLY, M; NICHOLSON, DC1
van der HELM, H; WAAGE, J1
HAEGER-ARONSEN, B1
HULUBEI, P; MIHAI, C; OANCEA, C1
KAY, IT; TADDEINI, L; WATSON, CJ1
GIARRUSSO, P; RASETTI, L; RUBINO, GF1
TOWNSEND, JD1
BOSSENMAIER, I; TADDEINI, L; WATSON, CJ1
SCOTT, DF1
MARKLE, V; PAZDER, LH; TAYLOR, JD1
DESPUY, ME; FRYDMAN, B; RAPOPORT, H1
CRAIG, JB; KAELBLING, R; PASAMANICK, B1
ARATO, G; BUDA, V; KELENYI, G; ORBAN, S1
HIGHTOWER, NC; MALOOLY, DA1
Quartarolo, AD; Russo, N; Sicilia, E1
Madhu, S; Rao, MR; Ravikanth, M; Shaikh, MS1
Bernardo-Seisdedos, G; Cooper, JB; Gu, S; Millet, O; Pickersgill, RW; Pluta, P; Rojas, AL; Roversi, P1

Reviews

2 review(s) available for pyrroles and porphobilinogen

ArticleYear
Tetrapyrrole assembly and modification into the ligands of biologically functional cofactors.
    Trends in biochemical sciences, 1990, Volume: 15, Issue:12

    Topics: Binding Sites; Hydroxymethylbilane Synthase; Ligands; Methylation; Porphobilinogen; Pyrroles; Tetrapyrroles; Uroporphyrinogens

1990
Pyrrolooxygenases: a new type of oxidases.
    Molecular and cellular biochemistry, 1973, Dec-15, Volume: 2, Issue:2

    Topics: Animals; Brain; Chloroplasts; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dipeptides; Escherichia coli; Hot Temperature; Hydrogen-Ion Concentration; Indoles; Kinetics; Liver; Microsomes; Mucor; Organ Specificity; Oxygenases; Plants; Porphobilinogen; Protein Denaturation; Pyrroles; Rats; Spleen; Tryptophan Oxygenase

1973

Other Studies

42 other study(ies) available for pyrroles and porphobilinogen

ArticleYear
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria.
    European journal of clinical investigation, 1979, Volume: 9, Issue:1

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinogen; Porphyrias; Pyrroles

1979
Pyrroles and related compounds. Part 38. Porphobilinogen synthesis.
    Journal of the Chemical Society. Perkin transactions 1, 1977, Issue:3

    Topics: Chemical Phenomena; Chemistry; Lactams; Methods; Methylation; Porphobilinogen; Pyrroles

1977
Delta aminolaevulinate dehydratase: its mechanism of action.
    The International journal of biochemistry, 1978, Volume: 9, Issue:12

    Topics: Histidine; Lysine; Macromolecular Substances; Models, Biological; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Sulfhydryl Compounds

1978
The purification and properties of uroporphyrinogen I synthases and uroporphyrinogen III cosynthase. Interactions between the enzymes.
    Annals of the New York Academy of Sciences, 1975, Apr-15, Volume: 244

    Topics: Ammonia-Lyases; Centrifugation, Density Gradient; Chromatography, Gel; Drug Stability; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Molecular Weight; Multienzyme Complexes; Plants; Porphobilinogen; Porphyrins; Protein Binding; Pyrroles

1975
Oxygen-regulated steps in the Rhodobacter capsulatus tetrapyrrole biosynthetic pathway.
    Journal of bacteriology, 1992, Volume: 174, Issue:16

    Topics: Aminolevulinic Acid; Bacteriochlorophylls; Oxygen; Porphobilinogen; Protoporphyrins; Pyrroles; Rhodobacter capsulatus; Tetrapyrroles

1992
Mutagenesis of arginine residues in the catalytic cleft of Escherichia coli porphobilinogen deaminase that affects dipyrromethane cofactor assembly and tetrapyrrole chain initiation and elongation.
    The Biochemical journal, 1991, Dec-01, Volume: 280 ( Pt 2)

    Topics: Amino Acid Sequence; Arginine; Catalysis; Chromatography, Liquid; Escherichia coli; Hydroxymethylbilane Synthase; Kinetics; Molecular Sequence Data; Mutagenesis; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Porphobilinogen; Pyrroles; Tetrapyrroles

1991
Evidence for a dipyrromethane cofactor at the catalytic site of E. coli porphobilinogen deaminase.
    FEBS letters, 1987, Dec-10, Volume: 225, Issue:1-2

    Topics: Ammonia-Lyases; Benzaldehydes; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Escherichia coli; Hydrogen-Ion Concentration; Hydroxymethylbilane Synthase; Indicators and Reagents; Porphobilinogen; Porphyrins; Pyrroles; Spectrophotometry

1987
Spectroscopic evidence for a porphobilinogen deaminase-tetrapyrrole complex that is an intermediate in the biosynthesis of uroporphyrinogen III.
    Biochemistry, 1988, Jun-28, Volume: 27, Issue:13

    Topics: Ammonia-Lyases; Hydroxymethylbilane Synthase; Magnetic Resonance Spectroscopy; Porphobilinogen; Porphyrinogens; Protein Binding; Pyrroles; Rhodobacter sphaeroides; Tetrapyrroles; Uroporphyrinogens

1988
Detection of urinary porphobilinogen.
    Lancet (London, England), 1973, Jun-30, Volume: 1, Issue:7818

    Topics: Humans; Indicators and Reagents; Porphobilinogen; Pyrroles

1973
[Preparation of porphobilinogen from -aminolevulinic acid by means of P. shermanii: remarkable effect of heat treatment].
    Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie, 1972, Volume: 27, Issue:4

    Topics: Hot Temperature; Levulinic Acids; Porphobilinogen; Propionibacterium; Pyrroles

1972
The enzymatic oxidation of porphobilinogen.
    FEBS letters, 1972, Oct-01, Volume: 26, Issue:1

    Topics: Ammonium Sulfate; Animals; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cobalt; Freezing; Ketones; Kinetics; Microsomes, Liver; NADP; Nickel; Oxygenases; Plants; Polarography; Porphobilinogen; Porphyrins; Pyrroles; Rats; Spectrophotometry; Sulfites

1972
New method for determination of aminolaevulinate dehydratase activity of human erythrocytes as an index of lead exposure.
    Clinical chemistry, 1974, Volume: 20, Issue:10

    Topics: Aminolevulinic Acid; Buffers; Colorimetry; Erythrocytes; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Indicators and Reagents; Lead Poisoning; Mathematics; Methods; Phosphates; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Trichloroacetic Acid

1974
Accumulation of porphobilinogen and other pyrroles by mutant and wild type Rhodopseudomonas spheroides: regulation by heme.
    Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Carboxy-Lyases; Chlorophyll; Feedback; Genetics, Microbial; Heme; Hydro-Lyases; Iron; Iron Isotopes; Levulinic Acids; Mutation; Phenanthrolines; Porphobilinogen; Porphyrins; Propionates; Puromycin; Pyrroles; Rhodobacter sphaeroides; Rhodopseudomonas

1972
Polypyrroles formed from porphobilinogen and amines by uroporphyrinogen synthetase of Rhodopseudomonas spheroides.
    The Biochemical journal, 1973, Volume: 133, Issue:3

    Topics: Amines; Ammonia; Ammonia-Lyases; Carbon Isotopes; Chromatography; Chromatography, Gel; Electrophoresis, Disc; Hydrogen-Ion Concentration; Hydroxylamines; Isoelectric Focusing; Methoxamine; Molecular Weight; Porphobilinogen; Porphyrins; Pyrroles; Rhodobacter sphaeroides; Rhodopseudomonas; Tritium

1973
Simple method for determination of urinary -aminolevulinic acid as an index of lead exposure.
    Clinical chemistry, 1972, Volume: 18, Issue:12

    Topics: Acetates; Acetoacetates; Clinical Enzyme Tests; Evaluation Studies as Topic; Humans; Indicators and Reagents; Lead Poisoning; Levulinic Acids; Male; Mass Screening; Methods; Porphobilinogen; Propionates; Pyrroles; Spectrophotometry; Time Factors

1972
Chemical and enzymatic polymerization of 2-aminomethyl-3,3'-carboxymethyl-4,4'-( -carboxyethyl)dipyrrylmethane.
    Biochemistry, 1973, Jan-02, Volume: 12, Issue:1

    Topics: Acetates; Aminohydrolases; Carbon Isotopes; Chemical Phenomena; Chemistry; Hot Temperature; Isomerases; Methane; Methylamines; Plants; Porphobilinogen; Propionates; Pyrroles; Stereoisomerism

1973
Synthesis of the pyrrole porphobilinogen by sepharose-linked -aminolevulinic acid dehydratase.
    Science (New York, N.Y.), 1973, Jun-15, Volume: 180, Issue:4091

    Topics: Binding Sites; Hydro-Lyases; Polysaccharides; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Rhodopseudomonas; Structure-Activity Relationship

1973
Porphobilinogen oxygenase from wheat germ: isolation, properties, and products formed.
    Biochemistry, 1973, Dec-18, Volume: 12, Issue:26

    Topics: Allosteric Regulation; Ammonium Sulfate; Chelating Agents; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Hydrogen-Ion Concentration; Iron; Kinetics; Lactams; Metalloproteins; Metals; Models, Chemical; Oxidation-Reduction; Oxygenases; Porphobilinogen; Pyridines; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Temperature; Triticum

1973
Mechanism of uroporphyrinogen biosynthesis from porphobilinogen.
    Enzyme, 1973, Volume: 16, Issue:1

    Topics: Aminohydrolases; Ammonia-Lyases; Carbon Radioisotopes; Chromatography, Paper; Plants; Porphobilinogen; Porphyrins; Pyrroles; Spectrophotometry; Triticum

1973
Urinary dipyrrylmethenes in patients with porphyria. A preliminary study of the brown pigments in the urine of a case of acute intermittent porphyria.
    Enzyme, 1974, Volume: 17, Issue:1

    Topics: Acute Disease; Adult; Bilirubin; Chromatography, Thin Layer; Humans; Male; Pigments, Biological; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles; Urobilin

1974
Mechanistic and thermodynamic considerations in the comparison of porphyrin organo-and biosyntheses.
    Enzyme, 1974, Volume: 17, Issue:1

    Topics: Aldehydes; Ammonia; Catalysis; Chlorine; Enzymes; Oxygen; Porphobilinogen; Porphyrins; Pyrroles; Thermodynamics

1974
On the chemistry of porphobilinogen synthesis of an aminomethyldipyrrylmethane.
    Enzyme, 1974, Volume: 17, Issue:1

    Topics: Alkylation; Chromatography, Ion Exchange; Hydrolysis; Lactams; Methods; Methylamines; Porphobilinogen; Propionibacterium; Pyrroles

1974
Intermittent acute porphyria--demonstration of a genetic defect in porphobilinogen metabolism.
    The New England journal of medicine, 1972, Jun-15, Volume: 286, Issue:24

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Erythrocytes; Feces; Female; Humans; Levulinic Acids; Lyases; Male; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Propionates; Pyrroles

1972
[Effect of heat on erythrocytic ALA-dehydratase activity in the rabbit and in man. II. Action of Pb and alpha-mercapto-propionyl-glycine in vitro, in man].
    Lavoro umano, 1971, Volume: 23, Issue:5

    Topics: Animals; Erythrocytes; Glycine; Hot Temperature; Humans; Hydro-Lyases; Lactates; Lead Poisoning; Levulinic Acids; Porphobilinogen; Pyrroles; Rabbits; Temperature

1971
Mechanism of action of porphobilinogen deaminase. The participation of stable enzyme substrate covalent intermediates between porphobilinogen and the porphobilinogen deaminase from Rhodopseudomonas spheroides.
    The Biochemical journal, 1981, Apr-01, Volume: 195, Issue:1

    Topics: Ammonia-Lyases; Chemical Phenomena; Chemistry; Chromatography, Gel; Hydroxylamines; Hydroxymethylbilane Synthase; Macromolecular Substances; Porphobilinogen; Pyrroles; Rhodobacter sphaeroides; Sodium Dodecyl Sulfate

1981
Excretion of porphobilinogen and 5-aminolaevulinic acid in acute porphyria.
    Lancet (London, England), 1961, Jun-10, Volume: 1, Issue:7189

    Topics: Amino Acids; Humans; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Pyrroles

1961
[A case of porphobilinogen excretion during a Somnifene cure].
    Nederlands tijdschrift voor geneeskunde, 1961, Mar-04, Volume: 105

    Topics: Barbiturates; Body Fluids; Humans; Porphobilinogen; Pyrroles

1961
Porphyria induced in the rabbit by diethyl 1,4-dihydro-2,4,6-trimethylpyridine-3,5-dicarboxylate. I. Excretion of 5-aminolaevulic acid, porphobilinogen, coproporphyrin and protoporphyrin.
    Acta pharmacologica et toxicologica, 1961, Volume: 18

    Topics: Amino Acids; Animals; Coproporphyrins; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Pyridines; Pyrroles; Rabbits

1961
[Clinical value of urinary pentdyopent and porphobilinogen in patients with hepatic and renal diseases].
    Medicina interna, 1963, Volume: 15

    Topics: Hemoglobins; Humans; Kidney Diseases; Liver Diseases; Porphobilinogen; Porphyrins; Pyrroles

1963
Inhibition of the Ehrlich's reaction of porphobilinogen by indican and related compounds.
    Clinica chimica acta; international journal of clinical chemistry, 1962, Volume: 7

    Topics: Indican; Indoles; Porphobilinogen; Porphyrins; Pyrroles

1962
Effect of glycine administration on gamma-aminolaevulic acid and porphobilinogen excretion in lead poisoning.
    Panminerva medica, 1962, Volume: 4

    Topics: Glycine; Humans; Lead Poisoning; Levulinic Acids; Porphobilinogen; Pyrroles

1962
AN EVALUATION OF A RECENT MODIFICATION OF THE WATSON-SCHWARTZ TEST FOR PORPHOBILINOGEN.
    Annals of internal medicine, 1964, Volume: 60

    Topics: Clinical Laboratory Techniques; Humans; Indicators and Reagents; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles; Urine

1964
PRESENT STATUS OF THE EHRLICH ALDEHYDE REACTION FOR URINARY PORPHOBILINOGEN.
    JAMA, 1964, Nov-09, Volume: 190

    Topics: Acetates; Alcohols; Aldehydes; Chloroform; Chromatography; Humans; Hydrochloric Acid; Indicators and Reagents; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles; Urine

1964
PORPHOBILINOGEN-LIKE CHROMOGENS IN URINE OF EPILEPTICS.
    British medical journal, 1965, Apr-10, Volume: 1, Issue:5440

    Topics: Diagnosis; Epilepsy; Humans; Indicators and Reagents; Metabolism; Naphthalenesulfonates; Porphobilinogen; Porphyrins; Pyrroles; Urine

1965
PORPHOBILINOGEN AND DELTA-AMINOLEVULINIC ACID EXCRETION IN MULTIPLE SCLEROSIS.
    Canadian Medical Association journal, 1965, Jun-26, Volume: 92

    Topics: Amino Acids; Aminolevulinic Acid; Demyelinating Diseases; Diagnosis, Differential; Fluids and Secretions; Humans; Levulinic Acids; Multiple Sclerosis; Neoplasms; Poliomyelitis; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles; Urine

1965
PYRROLES FROM AZAINDOLES. A SYNTHESIS OF PORPHOBILINOGEN.
    Journal of the American Chemical Society, 1965, Aug-05, Volume: 87

    Topics: Chemical Phenomena; Chemistry; Porphobilinogen; Porphyrins; Pyrroles; Research

1965
Urinary porphobilinogen. Results of screening 2,500 psychiatric patients.
    Archives of general psychiatry, 1961, Volume: 5

    Topics: Humans; Mental Disorders; Porphobilinogen; Porphyrins; Pyrroles

1961
[On the excretion of 5-aminolevulinic acid and porphobilinogen in latent porphyria].
    Folia haematologica (Leipzig, Germany : 1928), 1961, Volume: 78

    Topics: Amino Acids; Aminolevulinic Acid; Humans; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles

1961
Quantitative determination of porphobilinogen and delta-aminolevulinic acid in the urine.
    The Journal of laboratory and clinical medicine, 1962, Volume: 59

    Topics: Amino Acids; Aminolevulinic Acid; Humans; Porphobilinogen; Pyrroles

1962
Structures and electronic absorption spectra of a recently synthesised class of photodynamic therapy agents.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2006, Sep-06, Volume: 12, Issue:26

    Topics: Aza Compounds; Boron Compounds; Models, Molecular; Molecular Conformation; Photochemotherapy; Photosensitizing Agents; Porphobilinogen; Porphyrins; Pyrroles; Thermodynamics

2006
3,5-Diformylboron dipyrromethenes as fluorescent pH sensors.
    Inorganic chemistry, 2011, May-16, Volume: 50, Issue:10

    Topics: Benzoquinones; Biosensing Techniques; Boron; Boron Compounds; Crystallography, X-Ray; Dimethylformamide; Fluorescence; Fluorescent Dyes; Formamides; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; Porphobilinogen; Pyrroles; Spectrometry, Fluorescence; Thermodynamics

2011
Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
    Biochimica et biophysica acta. General subjects, 2018, Volume: 1862, Issue:9

    Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Humans; Hydroxymethylbilane Synthase; Polymerization; Porphobilinogen; Protein Conformation; Pyrroles; Uroporphyrinogens

2018