pyrroles has been researched along with pha 680632 in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballinari, D; Bravo, R; Cappella, P; Carpinelli, P; Ceruti, R; Croci, V; Fancelli, D; Gianellini, L; Giorgini, ML; Moll, J; Pesenti, E; Rusconi, L; Sola, F; Soncini, C; Storici, P; Varasi, M; Vianello, P; Zugnoni, P | 1 |
| Auperin, A; Bourhis, J; Deutsch, E; Frascogna, V; Lecluse, Y; Tao, Y; Zhang, P | 1 |
| Beeharry, N; Connolly, DC; Godwin, AK; Golemis, EA; Li, T; Litwin, S; Pathak, HB; Ratushny, V; Tikhmyanova, N; Weiner, LM; Xiao, F; Yen, TJ | 1 |
| Abeltino, M; Bonati, A; Cantoni, AM; Corradi, A; Donofrio, G; Giuliani, N; Lombardi, G; Lunghi, P; Mazzera, L; Ricca, M | 1 |
| Abeltino, M; Bonati, A; Cantoni, AM; Corradi, A; Lombardi, G; Lunghi, P; Mazzera, L; Naponelli, V; Perris, R; Ria, R; Ricca, M; Rizzi, FMA; Saltarella, I; Vacca, A | 1 |
5 other study(ies) available for pyrroles and pha 680632
| Article | Year |
|---|---|
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.
Topics: Animals; Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Biomarkers, Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HeLa Cells; HL-60 Cells; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Structure; Phenotype; Phosphorylation; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells.
Topics: Aneugens; Animals; Aurora Kinase A; Aurora Kinases; Cell Survival; Genes, p53; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Radiation-Sensitizing Agents; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2007 |
Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death.
Topics: Antineoplastic Agents; Apoptosis; Aurora Kinase A; Aurora Kinases; Cell Adhesion; Cell Line, Tumor; Dasatinib; Female; Humans; Mitosis; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazoles; Pyrimidines; Pyrroles; src-Family Kinases; Thiazoles | 2012 |
Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL.
Topics: Aged; Aged, 80 and over; Animals; Apoptosis; Aurora Kinase A; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; I-kappa B Kinase; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Multiple Myeloma; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays | 2013 |
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma.
Topics: Animals; Apoptosis; Aurora Kinase A; Aurora Kinase B; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; NF-kappa B; NF-kappaB-Inducing Kinase; Piperazines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrroles; STAT3 Transcription Factor; TNF Receptor-Associated Factor 2; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |