Compounds > pyrroles
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pyrroles and pf 956980

pyrroles has been researched along with pf 956980 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Changelian, PS; Doty, JL; Flanagan, ME; Harris, TM; Kent, CR; Kudlacz, EM; Kuhn, CF; Magnuson, KS; Moshinsky, D; Munchhof, MJ; Perregaux, DG; Sawyer, PS; Sun, J; Whipple, DA1
Cwynarski, K; Hart, SM; Hoffbrand, AV; Lowdell, MW; Prentice, AG; Samuel, ER; Steele, AJ; Wickremasinghe, RG1
Eguchi, K; Izumi, M; Izumi, Y; Jiuchi, Y; Kawakami, A; Kozuru, H; Migita, K; Motokawa, S; Nakamura, M; Nishino, Y; Nonaka, F; Satomura, K; Torigoshi, T1
Benson, BA; Dalmasso, AP; Goldish, D; Tsai, AK; Vercellotti, GM; Wasiluk, KR1
Arkin, J; Field, SD; Jones, LH; Li, J1

Other Studies

5 other study(ies) available for pyrroles and pf 956980

ArticleYear
The specificity of JAK3 kinase inhibitors.
    Blood, 2008, Feb-15, Volume: 111, Issue:4

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Enzyme Inhibitors; Graft Rejection; Humans; Janus Kinase 3; Kinetics; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Quinazolines

2008
The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.
    Blood, 2010, Nov-25, Volume: 116, Issue:22

    Topics: Apoptosis; bcl-X Protein; Bone Marrow Cells; Calcium-Calmodulin-Dependent Protein Kinases; Cytochromes c; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Leukemic; Humans; Interleukin-4; Janus Kinase 3; Leukemia, Lymphocytic, Chronic, B-Cell; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrroles; STAT6 Transcription Factor; Stromal Cells; T-Lymphocytes; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2010
Inhibition of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway in rheumatoid synovial fibroblasts using small molecule compounds.
    Clinical and experimental immunology, 2013, Volume: 174, Issue:3

    Topics: Arthritis, Rheumatoid; Fibroblasts; Humans; Janus Kinases; Oncostatin M; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; STAT Transcription Factors; Synovial Fluid; Synovial Membrane

2013
Interleukin-4 induces up-regulation of endothelial cell claudin-5 through activation of FoxO1: role in protection from complement-mediated injury.
    The Journal of biological chemistry, 2014, Jan-10, Volume: 289, Issue:2

    Topics: Animals; Cell Nucleus; Cell Survival; Cells, Cultured; Claudin-5; Complement System Proteins; Cytoplasm; Endothelial Cells; Forkhead Transcription Factors; Humans; Immunoblotting; Interleukin-4; Janus Kinase 3; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Protein Transport; Pyrimidines; Pyrroles; RNA Interference; STAT6 Transcription Factor; Swine; Up-Regulation

2014
Selective Downregulation of JAK2 and JAK3 by an ATP-Competitive pan-JAK Inhibitor.
    ACS chemical biology, 2017, 05-19, Volume: 12, Issue:5

    Topics: Adenosine Triphosphate; Binding, Competitive; Cells, Cultured; Down-Regulation; Humans; Immune System; Janus Kinase 2; Janus Kinase 3; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; RNA, Messenger

2017