Page last updated: 2024-08-18

pyrroles and pentylenetetrazole

pyrroles has been researched along with pentylenetetrazole in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's4 (28.57)18.2507
2000's2 (14.29)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baeyens, JM; Barrios, M; Del Pozo, E1
Freeman, JJ; Kosh, JW; Powers, DL; Sowell, JW1
Malinka, W; Tatarczyńska, E1
Almond, HR; Carmosin, RJ; Carson, JR; Pitis, PM; Stables, JP; Swinyard, EA; Vaught, JL; White, HS; Wolf, HH1
Engel, J; Günther, R; Höfgen, N; Hofmann, HJ; Lankau, HJ; Liebscher, J; Menzer, M; Müller, B; Rolfs, A; Rostock, A; Unverferth, K1
Ashkenazi, S; Chrousos, GP; Ovadia, H; Weizman, A; Yuhas, Y1
Arnold, T; Dost, R; Egerland, U; Grunwald, C; Höfgen, N; Hofmann, HJ; Lankau, HJ; Rundfeldt, C; Unverferth, K1
Akgün-Dar, K; Aksu, U; Uzüm, G1
de Mello, CF; de Oliveira, CV; Ferreira, J; Funck, VR; Furian, AF; Guerra, GP; Mallmann, CA; Oliveira, MS; Pereira, LM; Rambo, LM; Ribeiro, LR; Royes, LF1
Dehpour, AR; Fakhrzad, A; Hassanipour, M; Hassanpour, S; Moezi, L; Shafaroodi, H1
Emamzadeh-Fard, S; Moazzami, K; Shabani, M1
Dehpour, AR; Fakhrzad, A; Hassanipour, M; Moezi, L; Rezayat, M; Shafaroodi, H1
Chońska, J; Dawidowski, M; Mika, W; Turło, J1
Bhardwaj, V; Bharti, R; Das, P; Kumari, S; Mazumder, AG; Purohit, R; Singh, D; Tanwar, G1

Other Studies

14 other study(ies) available for pyrroles and pentylenetetrazole

ArticleYear
Effects of potassium channel openers on pentylenetetrazole-induced seizures in mice.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:2

    Topics: 4-Aminopyridine; Animals; Benzopyrans; Cromakalim; Drug Antagonism; Female; Guanidines; Mice; Pentylenetetrazole; Pinacidil; Potassium Channels; Pyrroles; Seizures

1990
Anticonvulsant properties of selected pyrrolo[2,3-d]pyrimidine-2,4-diones and intermediates.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:4

    Topics: Animals; Anticonvulsants; Electroshock; Male; Mice; Pentylenetetrazole; Phenytoin; Pyrimidinones; Pyrroles; Seizures; Solubility; Structure-Activity Relationship; Trimethadione

1980
Synthesis and pharmacological properties of N-(4-substituted-1-piperazinylalkyl)-1-butyl-2,5-dimethylpyrrole-3,4- dicarboxyimide derivatives.
    Farmaco (Societa chimica italiana : 1989), 1993, Volume: 48, Issue:7

    Topics: Animals; Anticonvulsants; Apomorphine; Central Nervous System Agents; Chemical Phenomena; Chemistry, Physical; Fever; Helplessness, Learned; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Motor Activity; Pain Measurement; Pentylenetetrazole; Piperazines; Pyrroles; Rats; Rats, Wistar; Reserpine; Serotonin Receptor Agonists

1993
Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Anesthesia; Animals; Anticonvulsants; Bicuculline; Calcium; Cerebellum; Electroshock; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Piperidines; Potassium; Pyrroles; Rats; Seizures; Structure-Activity Relationship; Veratridine

1997
Synthesis, anticonvulsant activity, and structure-activity relationships of sodium channel blocking 3-aminopyrroles.
    Journal of medicinal chemistry, 1998, Jan-01, Volume: 41, Issue:1

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Indicators and Reagents; Male; Mice; Models, Molecular; Molecular Structure; Motor Activity; Neurotoxins; Pentylenetetrazole; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Sodium Channel Blockers; Structure-Activity Relationship

1998
Involvement of the neuropeptide corticotropin-releasing hormone in an animal model of Shigella-related seizures.
    Journal of neuroimmunology, 2004, Volume: 153, Issue:1-2

    Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Pyrimidines; Pyrroles; Seizures; Shigella; Time Factors

2004
Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors.
    Journal of medicinal chemistry, 2006, Mar-23, Volume: 49, Issue:6

    Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anticonvulsants; Binding Sites; Brain; GABA Antagonists; GABA-A Receptor Agonists; Imidazoles; Male; Mice; Models, Molecular; Morpholines; Pentylenetetrazole; Piperidines; Pyrroles; Quantitative Structure-Activity Relationship; Radioligand Assay; Rats; Rats, Wistar; Rotarod Performance Test; Seizures

2006
The effects of atorvastatin on memory deficit and seizure susceptibility in pentylentetrazole-kindled rats.
    Epilepsy & behavior : E&B, 2010, Volume: 19, Issue:3

    Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Atorvastatin; Avoidance Learning; Disease Susceptibility; Electroencephalography; Heptanoic Acids; Kindling, Neurologic; Male; Memory Disorders; Pentylenetetrazole; Pyrroles; Rats; Rats, Wistar; Reaction Time; Seizures

2010
Differential effects of atorvastatin treatment and withdrawal on pentylenetetrazol-induced seizures.
    Epilepsia, 2011, Volume: 52, Issue:11

    Topics: Animals; Anticonvulsants; Atorvastatin; Blood-Brain Barrier; Cerebral Cortex; Cholesterol; Convulsants; Electroencephalography; Heptanoic Acids; Male; Pentylenetetrazole; Pyrroles; Rats; Rats, Wistar; Seizures; Simvastatin

2011
Chronic administration of atorvastatin induced anti-convulsant effects in mice: the role of nitric oxide.
    Epilepsy & behavior : E&B, 2012, Volume: 23, Issue:4

    Topics: Analysis of Variance; Animals; Anticonvulsants; Atorvastatin; Convulsants; Disease Models, Animal; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Guanidines; Heptanoic Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrroles; Seizures; Time Factors

2012
Anticonvulsive effect of atorvastatin on pentylenetetrazole-induced seizures in mice: the role of nitric oxide pathway.
    Fundamental & clinical pharmacology, 2013, Volume: 27, Issue:4

    Topics: Animals; Anticonvulsants; Arginine; Atorvastatin; Heptanoic Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrroles; Seizures; Signal Transduction

2013
The involvement of nitric oxide in the anti-seizure effect of acute atorvastatin treatment in mice.
    Neurological research, 2012, Volume: 34, Issue:9

    Topics: Animals; Anticonvulsants; Atorvastatin; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Enzyme Inhibitors; Epilepsy, Tonic-Clonic; Guanidines; Heptanoic Acids; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrroles

2012
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship

2014
Target identification, screening and in vivo evaluation of pyrrolone-fused benzosuberene compounds against human epilepsy using Zebrafish model of pentylenetetrazol-induced seizures.
    Scientific reports, 2019, 05-27, Volume: 9, Issue:1

    Topics: Animals; Anticonvulsants; Class I Phosphatidylinositol 3-Kinases; Coumarins; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Gene Expression Profiling; Gene Expression Regulation; Humans; Molecular Docking Simulation; Pentylenetetrazole; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; TOR Serine-Threonine Kinases; Zebrafish; Zebrafish Proteins

2019