pyrroles has been researched along with oxazolidin-2-one in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 18 (58.06) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Cumberbatch, MJ; Hargreaves, RJ; Hill, RG | 1 |
| Artico, M; Befani, O; Esposito, M; Giovannini, V; Mai, A; Massa, S; Mondovì, B; Sbardella, G; Turini, P | 1 |
| Artico, M; Esposito, M; Mai, A; Massa, S; Ragno, R; Sbardella, G | 1 |
| Pyne, SG; Tang, M | 1 |
| Barrett, JF; Bronson, JJ; D'Andrea, SV; DenBleyker, KL; Frosco, M; Fung-Tomc, JC; Gill, P; Marinier, A; Martel, A; Mate, R; Meng, Z; Quesnelle, CA; Snyder, LB | 1 |
| Chapuis, JC; Doubek, DL; Ducki, S; Herald, DL; Pettit, GR; Schmidt, JM | 1 |
| Dong, G; Trost, BM | 2 |
| Awasthi, R; Das, J; Iqbal, J; Kannan, M; Laxman Rao, CV; Patil, SN; Prasad Narasimhulu, C; Rao Mamidi, NV; Roshaiah, M; Sarnaik, HM; Sastry, TV; Selvakumar, N; Sitaram Kumar, M; Subrahmanyam, D | 1 |
| Baumgardt, I; Butenschön, H; Cao, W; Erden, I; Gärtner, C; Hoarau, C; Ozer, G; Song, J | 1 |
| Bloomfield, D; Carlson, GL; Littlejohn, TW; McKenney, JM; Mitchel, Y; Pasternak, RC; Sapre, A; Sisk, CM; Tribble, D | 1 |
| Du Bois, J; Wehn, PM | 1 |
| Al-Mourabit, A; Debitus, C; Ermolenko, L; Gallard, JF; Martin, MT; Moriou, C; Patel, K; Petek, S; Sorres, J; Tilvi, S | 1 |
| Buszewski, B; Fuchs, P; Kegler, R; Miekisch, W; Mundkowski, RG; Olszowy, P; Schubert, JK; Szultka, M | 1 |
| Nuermberger, EL; Spigelman, MK; Yew, WW | 1 |
| Buszewski, B; Fuchs, P; Kegler, R; Miekisch, W; Mundkowski, R; Olszowy, P; Schubert, J; Szultka, M | 1 |
| Bergman, AJ; Dockendorf, MF; Dykstra, K; Green, M; Krishna, R; Wagner, JA | 1 |
| Jialal, I; Kaur, J | 1 |
| Buszewski, B; Nowaczyk, J; Olszowy, P; Szultka, M | 1 |
| Agostinelli, E; Mai, A; Saccoccio, S; Tempera, G; Tomassi, S; Valente, S | 1 |
| Buszewski, B; Jackowski, M; Szeliga, J; Szultka, M | 1 |
| Ballante, F; Biava, M; Costi, R; De Vita, D; Di Santo, R; Feroci, M; Friggeri, L; Manetti, F; Musmuca, I; Ragno, R; Scipione, L; Tortorella, S | 1 |
| Chandrakant, B; Kalia, NP; Kamal, A; Khan, IA; Kumar, S; Narasimha Rao, MP; Shaik, AB; Sharma, S; Shetti, RV; Sultana, F; Swapna, P | 1 |
| Kikuchi, M; McCrary Sisk, C; Nakagomi, M; Numaguchi, H; Shirakawa, M; Surks, HK; Tamura, S; Teramoto, T | 1 |
| Batey, RA; Duspara, PA | 1 |
| Havekes, LM; Jukema, JW; Kühnast, S; Landmesser, U; Lüscher, TF; Pieterman, E; Princen, HM; Rensen, PC; Simic, B; van der Hoorn, JW; van der Tuin, SJ; van Klinken, JB; Willems van Dijk, K | 1 |
| Chen, X; Gordeev, MF; Li, C; Li, L; Liu, J; Meng, J; Xie, C; Yuan, H; Yuan, Z; Zhong, D; Zhou, J | 1 |
| Baer, AL; deGoma, EM; Donovan, DS; Dunbar, RL; Ginsberg, HN; Gutstein, DE; Holleran, S; Johnson-Levonas, AO; Jumes, P; Karmally, W; Lassman, ME; Liu, Y; Millar, JS; Obunike, J; Pollan, L; Rader, DJ; Rafeek, H; Ramakrishnan, R; Reyes-Soffer, G; Tohyama, J; Wagner, JA | 1 |
| Azam, MA; Jubie, S; Thathan, J | 1 |
| Álvarez de la Rosa, D; Gerona-Navarro, G; González-Muñiz, R; Martín-Martínez, M; Pérez-Gordillo, FL; Rodríguez, Y; Zhou, MM | 1 |
| Karkara, BB; Kumar, A; Panda, G | 1 |
4 review(s) available for pyrroles and oxazolidin-2-one
| Article | Year |
|---|---|
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors.
Topics: Amino Acid Sequence; Animals; Drug Evaluation, Preclinical; Humans; Molecular Sequence Data; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazolidinones; Pyrroles; Stereoisomerism | 2003 |
Current development and future prospects in chemotherapy of tuberculosis.
Topics: Adamantane; Animals; Antitubercular Agents; Carbapenems; Clinical Trials as Topic; Diarylquinolines; Drug Delivery Systems; Ethylenediamines; Fluoroquinolones; Humans; Isonicotinic Acids; Mice; Mycobacterium tuberculosis; Nitroimidazoles; Oxazolidinones; Patient Compliance; Pyrroles; Quinolines; Rifamycins; Tuberculosis, Pulmonary | 2010 |
Dual targeting DNA gyrase B (GyrB) and topoisomerse IV (ParE) inhibitors: A review.
Topics: Amino Acid Sequence; Aminopyridines; Anti-Bacterial Agents; Barbiturates; Benzimidazoles; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Indazoles; Isoxazoles; Morpholines; Organophosphates; Oxazolidinones; Prodrugs; Pyrazoles; Pyrroles; Pyrrolidines; Pyrrolidinones; Quinazolinones; Quinolines; Spiro Compounds; Topoisomerase II Inhibitors; Topoisomerase Inhibitors; Urea | 2015 |
Novel candidates in the clinical development pipeline for TB drug development and their synthetic approaches.
Topics: Adamantane; Animals; Antitubercular Agents; DNA Gyrase; Drug Development; Enzyme Inhibitors; Humans; Isonicotinic Acids; Mycobacterium tuberculosis; Oxazolidinones; Piperidines; Pyrroles; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant; Uridine | 2021 |
3 trial(s) available for pyrroles and oxazolidin-2-one
| Article | Year |
|---|---|
Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patients.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol Ester Transfer Proteins; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Female; Heptanoic Acids; Humans; Male; Middle Aged; Oxazolidinones; Pyrroles; Treatment Outcome | 2009 |
Efficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib in Japanese patients with dyslipidemia.
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol Ester Transfer Proteins; Dose-Response Relationship, Drug; Double-Blind Method; Dyslipidemias; Female; Gene Expression Regulation; Heptanoic Acids; Humans; Japan; Male; Middle Aged; Oxazolidinones; Patient Safety; Pyrroles; Time Factors; Treatment Outcome; Young Adult | 2013 |
Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein B-100; Atorvastatin; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, LDL; Male; Middle Aged; Oxazolidinones; Pyrroles; Time Factors; Triglycerides | 2015 |
24 other study(ies) available for pyrroles and oxazolidin-2-one
| Article | Year |
|---|---|
The effects of 5-HT1A, 5-HT1B and 5-HT1D receptor agonists on trigeminal nociceptive neurotransmission in anaesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analgesics; Animals; Electric Stimulation; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1998 |
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.
Topics: Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazolidinones; Pyrroles | 2002 |
Asymmetric synthesis of (-)-7-epiaustraline and (+)-1,7-diepiaustraline.
Topics: Hydroxylation; Models, Molecular; Oxazolidinones; Pyrroles; Pyrrolizidine Alkaloids; Stereoisomerism | 2003 |
Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Isoxazoles; Microbial Sensitivity Tests; Models, Molecular; Nitrogen; Oxazolidinones; Oxazolone; Pyrroles; Stereoisomerism; Structure-Activity Relationship | 2004 |
Antineoplastic agents 470. Absolute configuration of the marine sponge bromopyrrole agelastatin A.
Topics: Alkaloids; Animals; Antineoplastic Agents; Molecular Conformation; Oxazolidinones; Porifera; Pyrroles; X-Ray Diffraction | 2005 |
New class of nucleophiles for palladium-catalyzed asymmetric allylic alkylation. Total synthesis of agelastatin A.
Topics: Alkaloids; Alkylation; Allyl Compounds; Amides; Catalysis; Cyclopentanes; Oxazolidinones; Palladium; Pyrroles; Stereoisomerism | 2006 |
Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones.
Topics: Anti-Bacterial Agents; Benzazepines; Molecular Mimicry; Oxazolidinones; Pyrroles; Structure-Activity Relationship | 2006 |
Photooxygenation of 5-dialkylamino-4-pyrrolin-3-ones. Synthesis of highly functionalized ureas, 2-oxazolidinones, and 2-oxazolinones.
Topics: Acetates; Alkanes; Alkynes; Amidines; Amines; Catalysis; Cyclization; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Hydrogenation; Methanol; Models, Chemical; Oxazoles; Oxazolidinones; Oxygen; Photochemistry; Pyrroles; Solvents; Urea | 2008 |
A stereoselective synthesis of the bromopyrrole natural product (-)-agelastatin A.
Topics: Alkaloids; Biological Products; Bromine Compounds; Catalysis; Heterocyclic Compounds, 1-Ring; Molecular Structure; Oxazolidinones; Pyrroles; Rhodamines; Stereoisomerism; Sulfonic Acids; Thiazepines | 2009 |
A stereodivergent strategy to both product enantiomers from the same enantiomer of a stereoinducing catalyst: agelastatin A.
Topics: Alkaloids; Catalysis; Copper; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Oxazolidinones; Palladium; Pyrroles; Stereoisomerism | 2009 |
Agelastatin E, agelastatin F, and benzosceptrin C from the marine sponge Agelas dendromorpha.
Topics: Agelas; Alkaloids; Animals; Drug Screening Assays, Antitumor; Humans; Imidazoles; KB Cells; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxazolidinones; Pyrroles | 2010 |
Polypyrrole solid phase microextraction: A new approach to rapid sample preparation for the monitoring of antibiotic drugs.
Topics: Acetamides; Anti-Bacterial Agents; Anticoagulants; Aza Compounds; Chromatography, High Pressure Liquid; Daptomycin; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Linezolid; Moxifloxacin; Oxazolidinones; Polymers; Pyrroles; Quinolines; Salts; Solid Phase Microextraction | 2010 |
New coated SPME fibers for extraction and fast HPLC determination of selected drugs in human blood.
Topics: Acetamides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Daptomycin; Humans; Linezolid; Oxazolidinones; Polymers; Pyrroles; Solid Phase Microextraction; Thiophenes | 2010 |
Model-based development of anacetrapib, a novel cholesteryl ester transfer protein inhibitor.
Topics: Anticholesteremic Agents; Atorvastatin; Biological Availability; Capsules; Cholesterol Ester Transfer Proteins; Computer Simulation; Diet, Fat-Restricted; Dose-Response Relationship, Drug; Drug Design; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Models, Biological; Nonlinear Dynamics; Oxazolidinones; Pyrroles; Tablets | 2011 |
The cholesterol ester transfer protein inhibitor, anacetrapib.
Topics: Atorvastatin; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Drug Therapy, Combination; Heptanoic Acids; Humans; Oxazolidinones; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
A new way of solid-phase microextraction fibers preparation for selected antibiotic drug determination by HPLC-MS.
Topics: Acetamides; Anti-Infective Agents; Chromatography, High Pressure Liquid; Humans; Linear Models; Linezolid; Mass Spectrometry; Models, Chemical; Oxazolidinones; Ozone; Polymers; Pyrroles; Reproducibility of Results; Solid Phase Microextraction; Thiophenes | 2011 |
Novel reversible monoamine oxidase A inhibitors: highly potent and selective 3-(1H-pyrrol-3-yl)-2-oxazolidinones.
Topics: Animals; Cattle; In Vitro Techniques; Isoenzymes; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazolidinones; Pyrroles; Stereoisomerism; Structure-Activity Relationship | 2011 |
Development of novel molecularly imprinted solid-phase microextraction fibers and their application for the determination of antibiotic drugs in biological samples by SPME-LC/MS(n).
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Daptomycin; Humans; Linezolid; Mass Spectrometry; Molecular Imprinting; Oxazolidinones; Polymers; Pyrroles; Sensitivity and Specificity; Solid Phase Microextraction; Thiophenes | 2012 |
Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents.
Topics: Antitubercular Agents; Drug Design; Humans; Models, Molecular; Mycobacterium tuberculosis; Oxazolidinones; Pyrroles; Quantitative Structure-Activity Relationship; Tuberculosis | 2013 |
Anti-tubercular agents. Part 7: a new class of diarylpyrrole-oxazolidinone conjugates as antimycobacterial agents.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Oxazolidinones; Pyrroles; Structure-Activity Relationship | 2013 |
A short total synthesis of the marine sponge pyrrole-2-aminoimidazole alkaloid (±)-agelastatin A.
Topics: Alkaloids; Animals; Cyclization; Imidazoles; Oxazolidinones; Porifera; Pyrroles; Stereoisomerism | 2013 |
Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Disease Progression; Drug Combinations; Female; Heptanoic Acids; Mice, Transgenic; Oxazolidinones; Pyrroles; Serum Amyloid A Protein | 2015 |
Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: the oxidative ring opening of 2,3-Dihydropyridin-4-one catalyzed by non-P450 enzymes.
Topics: Anti-Bacterial Agents; Catalysis; Cytochrome P-450 Enzyme System; Feces; Humans; Indans; Liver; Male; Microsomes, Liver; Oxazolidinones; Oxidation-Reduction; Pyridones; Pyrroles | 2015 |
Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects.
Topics: Amino Acid Sequence; Animals; Benzoxazines; Dihydropyridines; Drug Discovery; Humans; Ligands; Macrolides; Mineralocorticoid Receptor Antagonists; Models, Molecular; Oxazolidinones; Peptides; Pyrazoles; Pyrroles; Receptors, Mineralocorticoid; Structure-Activity Relationship; Sulfonamides | 2017 |