pyrroles has been researched along with oligonucleotides in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.94) | 18.7374 |
| 1990's | 7 (10.29) | 18.2507 |
| 2000's | 32 (47.06) | 29.6817 |
| 2010's | 22 (32.35) | 24.3611 |
| 2020's | 5 (7.35) | 2.80 |
| Authors | Studies |
|---|---|
| Fric, I; Luck, G; Zimmer, C | 1 |
| Boyd, M; Denny, WA; Gravatt, GL; Lee, HH | 1 |
| Broggini, M; D'Incalci, M; Mantovani, R; Mongelli, N; Ottolenghi, S; Ponti, M | 1 |
| Animati, F; Arcamone, F; Ciucci, A; Feriotto, G; Gambari, R; Giacomini, P; Lombardi, P; Mischiati, C; Natali, PG | 1 |
| Barthet, C; Bidan, G; Dejean, E; Livache, T; Roget, A; Téoule, R | 1 |
| Bidan, G; Fouque, B; Livache, T; Marchand, J; Mathis, G; Roget, A; Téoule, R | 1 |
| Bergstrom, DE; Glass, GA; Hua, P; Kinsey, BM; Klysik, J; Orson, FM; Ward, B | 1 |
| Bazin, H; Livache, T; Mathis, G | 1 |
| Asai, A; Mizukami, T; Nakano, H; Yano, K | 1 |
| Abrantes, LM; Correia, JP; Lassalle, N; Vieil, E | 1 |
| Oliver, JS; Parker, KA; Suggs, JW | 1 |
| Bruice, TW; Gonzalez, C; Moore, M; Ribeiro, S; Schmitz, U; Schroth, GP; Turin, L | 1 |
| Korri-Youssoufi, H; Yassar, A | 1 |
| Haneda, M; Inoki, K; Kikkawa, R; Koya, D; Maeda, S; Nishio, T | 1 |
| Hecker, M; Schwabe, O; Wagner, AH | 1 |
| Liedl, KR; Loferer, MJ; Mayer, E; Rauch, C; Trieb, M; Wellenzohn, B; Winger, RH | 1 |
| Bando, T; Narita, A; Saito, I; Sugiyama, H | 1 |
| Bando, T; Sugiyama, H; Takahashi, R | 1 |
| Johnson, AA; Marchand, C; Pommier, Y | 1 |
| Asada, K; Ayame, H; Bando, T; Narita, A; Sugiyama, H | 1 |
| Coulombe, RA; Rieben, WK | 1 |
| Calemczuk, R; Knorr, N; Livache, T; Szunerits, S | 1 |
| Yuan, G; Zhou, J | 1 |
| Aldissi, M; Bogomolova, A; Komarova, E | 1 |
| Ayame, H; Bando, T; Fukuda, N; Lai, YM; Matsuda, H; Matsumoto, K; Mugishima, H; Saito, S; Serie, K; Sugiyama, H; Ueno, T | 1 |
| Carloni, P; Rothlisberger, U; Spiegel, K | 1 |
| Li, H; Yuan, G | 1 |
| Chenoweth, DM; Dervan, PB; Doss, RM; Foister, S; Marques, MA | 1 |
| von Mehren, M | 1 |
| Bode, BE; Engels, JW; Piton, N; Plackmeyer, J; Prisner, TF; Schiemann, O | 1 |
| Bui, B; Italiano, A | 1 |
| Apice, G; Bruni, GS; Caponigro, F; Iaffaioli, RV; Milano, A | 1 |
| Feng, CL; Liang, P; Peng, D; Yan, F; Zhang, Z; Zhao, R; Zheng, X | 1 |
| Lee, CB; Socinski, MA | 1 |
| Jang, J; Ko, S | 1 |
| Schuster, GB; Srinivasan, S | 1 |
| Hudson, RH; Wojciechowski, F | 1 |
| Brodbelt, JS; Jayawickramarajah, J; Lawrence, CM; Pierce, SE; Sessler, JL; Sherman, CL | 1 |
| Boutorine, A; Buchmann, W; De Pauw, E; Halby, L; Tortajada, J | 1 |
| Sherman, SI | 1 |
| Moretti, S; Puxeddu, E; Romagnoli, S; Voce, P | 1 |
| Kopecky, K; Kucera, R; Miletin, M; Novakova, V; Zimcik, P | 1 |
| Bouchain-Gautier, C; Bourgoin, JP; Descamps, E; Filoramo, A; Goffman, M; Goux-Capes, L; Livache, T; Mailley, P; Nguyen, K | 1 |
| Boulton, ME; Cai, J; Han, S; Law, B; Liao, D; Qing, R | 1 |
| James, CH; Rahman, KM; Thurston, DE | 1 |
| Filichev, VV; Partridge, AC; Stephenson, AW | 1 |
| Arango, BA; Cohen, EE; Perez, CA; Raez, LE; Santos, ES | 1 |
| Fukuda, N; Matsuda, H; Matsumoto, K; Matsumoto, Y; Nagase, H; Saito, K; Ueno, T; Wan, JX; Watanabe, T | 1 |
| Cooper, J; Danley, D; Lyon, W; Maurer, K; Wilmoth, J; Yazvenko, N | 1 |
| Mihranyan, A; Nyholm, L; Nyström, G; Razaq, A; Strømme, M | 1 |
| Döme, B; Török, S | 1 |
| Allan, KE; Ellis, AV; Khodakov, DA; Kobus, HJ; Lenehan, CE | 1 |
| Engelke, DR; Good, PD; Haeusler, RA; Hopper, AK; McLeod, IX; Miller, EL; Pai, DA; Pratt-Hyatt, M; Wozniak, GG; Yates, JR | 1 |
| Afonso, R; Angeles, C; Campos, JM; García-Alfonso, P; Grande, E; Jorge, M; Martínez, V; Montagut, C; Polo, E; Reina, JJ | 1 |
| Abe, K; Fewell, JG; Gerthoffer, WT; Joshi, SR; Matar, M; McLendon, JM; McMurtry, IF; Oka, M; Sparks, J | 1 |
| Gemma, A; Miyanaga, A | 1 |
| Covell, LL; Ganti, AK | 1 |
| Bandaru, S; Dunna, NR; Girdhar, A; Hussain, T; Kandula, V; Nayarisseri, A; Pudutha, A | 1 |
| Dulai, PS; Sandborn, WJ | 1 |
| Abraham, C; Dulai, PS; Sandborn, WJ; Vermeire, S | 1 |
| Boland, BS; Vermeire, S | 1 |
| Basher, MA; Fox, KR; Jackson, PJM; Rahman, KM; Thurston, DE | 1 |
| Buzon, B; Grainger, R; Huang, S; Junop, MS; Rzadki, C | 1 |
| Chari, RVJ; Harris, L; Keating, TA; Miller, ML; Reid, EE; Salomon, PL; Singh, R | 1 |
| Fani, M; Gholami, M; Makvandi, M; Meshkat, Z; Pourianfar, HR; Rezaee, SA; Rezayi, M | 1 |
| Kondhare, D; Leonard, P; Seela, F; Zhang, A | 1 |
| Bax, BD; Burley, GA; McDonald, NQ; Shelkovnikova, T; Sutormin, D | 1 |
| Buchberger, A; Fahmi, NE; Henry, SJW; MacCulloch, T; Novacek, A; Simmons, CR; Stephanopoulos, N; Yan, H | 1 |
17 review(s) available for pyrroles and oligonucleotides
| Article | Year |
|---|---|
HIV-1 integrase inhibitors: a decade of research and two drugs in clinical trial.
Topics: Acetoacetates; Anti-HIV Agents; Biological Factors; Caffeic Acids; Clinical Trials as Topic; Furans; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Humans; Indoles; Models, Molecular; Molecular Structure; Oligonucleotides; Pyrroles; Reverse Transcriptase Inhibitors; Succinates; Tetrazoles; Triazoles | 2004 |
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bevacizumab; Clinical Trials as Topic; Dasatinib; Drug Resistance, Neoplasm; Everolimus; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Niacinamide; Oligonucleotides; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sirolimus; Staurosporine; Sunitinib; Thiazoles | 2006 |
[Gastrointestinal stromal tumors: molecular aspects and therapeutic implications].
Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Proteins; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sorafenib; Staurosporine; Sunitinib; Thiazoles | 2008 |
Medical treatment of gastrointestinal stromal tumors: state of the art and future perspectives.
Topics: Antineoplastic Agents; Benzamides; Chemotherapy, Adjuvant; Dioxoles; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Neoadjuvant Therapy; Niacinamide; Oligonucleotides; Phthalazines; Piperazines; Proto-Oncogene Mas; Pyridines; Pyrimidines; Pyrroles; Sunitinib; Tetrahydroisoquinolines; Trabectedin | 2006 |
Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a review of recent clinical trials.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Humans; Indoles; Neovascularization, Pathologic; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperidines; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Treatment Outcome | 2007 |
Tyrosine kinase inhibitors and the thyroid.
Topics: Axitinib; Benzenesulfonates; Clinical Trials as Topic; Gefitinib; Humans; Imidazoles; Indazoles; Indoles; Niacinamide; Oligonucleotides; Pharmaceutical Preparations; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins B-raf; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thyroid Gland; Thyroid Neoplasms | 2009 |
Targeted molecular therapies in thyroid carcinoma.
Topics: Antineoplastic Agents; Axitinib; Benzenesulfonates; Carcinoma, Medullary; Carcinoma, Papillary; Humans; Imidazoles; Indazoles; Indoles; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thyroid Neoplasms | 2009 |
In pursuit of new anti-angiogenic therapies for cancer treatment.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Drug Resistance, Neoplasm; Humans; Indazoles; Indoles; Neoplasms; Neovascularization, Pathologic; Niacinamide; Oligonucleotides; Phenylurea Compounds; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Sorafenib; Sulfonamides; Sunitinib; Tumor Microenvironment | 2011 |
Novel molecular targeted therapies for refractory thyroid cancer.
Topics: Angiogenesis Inhibitors; Anilides; Antineoplastic Agents; Axitinib; Benzamides; Benzenesulfonates; Benzoquinones; Bibenzyls; Boronic Acids; Bortezomib; Depsipeptides; ErbB Receptors; Gefitinib; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Imatinib Mesylate; Imidazoles; Indazoles; Indoles; Lactams, Macrocyclic; Lenalidomide; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thalidomide; Thyroid Neoplasms; Valproic Acid; Vorinostat | 2012 |
[Possibilities for inhibiting tumor-induced angiogenesis: results with multi-target tyrosine kinase inhibitors].
Topics: Angiogenesis Inhibitors; Animals; Axitinib; Benzenesulfonates; Humans; Imidazoles; Indazoles; Indoles; Neoplasms; Neovascularization, Pathologic; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sorafenib; Sulfonamides; Sunitinib | 2012 |
The role of antiangiogenic agents in the treatment of patients with advanced colorectal cancer according to K-RAS status.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Axitinib; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; ErbB Receptors; Fluorouracil; Genes, ras; Humans; Imidazoles; Indazoles; Indoles; Irinotecan; Niacinamide; Oligonucleotides; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics; Phenylurea Compounds; Prognosis; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Signal Transduction; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A | 2014 |
[Anti-angiogenesis and molecular targeted therapies].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Humans; Indoles; Molecular Targeted Therapy; Neoplasms; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A | 2015 |
Treatment of advanced thyroid cancer: role of molecularly targeted therapies.
Topics: Anilides; Antineoplastic Agents; Axitinib; Carcinoma, Neuroendocrine; DNA Mutational Analysis; Drug Approval; Humans; Imidazoles; Indazoles; Indoles; MAP Kinase Signaling System; Molecular Targeted Therapy; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-ret; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Sorafenib; Sulfonamides; Sunitinib; Thyroid Neoplasms; United States; United States Food and Drug Administration; Vascular Endothelial Growth Factor A | 2015 |
Next-Generation Therapeutics for Inflammatory Bowel Disease.
Topics: Antibodies, Monoclonal, Humanized; Biological Products; Cell Adhesion Molecules; Gastrointestinal Agents; Humans; Immunoglobulins; Indans; Inflammatory Bowel Diseases; Mucoproteins; Oligonucleotides; Oxadiazoles; Piperidines; Pyrimidines; Pyrroles; Tumor Necrosis Factor-alpha; Ustekinumab | 2016 |
Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cytokines; Humans; Inflammatory Bowel Diseases; Interleukin-23; Janus Kinases; Lysophospholipids; Molecular Targeted Therapy; Oligonucleotides; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; Smad7 Protein; Sphingosine; Th17 Cells; Transforming Growth Factor beta; Ustekinumab | 2017 |
Janus Kinase Antagonists and Other Novel Small Molecules for the Treatment of Crohn's Disease.
Topics: B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Humans; Indans; Janus Kinase 1; Janus Kinase Inhibitors; Oligonucleotides; Oxadiazoles; Piperidines; Pyridines; Pyrimidines; Pyrroles; Receptors, Lysosphingolipid; Smad7 Protein; T-Lymphocytes; Triazoles | 2017 |
Oligonucleotide-Recognizing Topoisomerase Inhibitors (OTIs): Precision Gene Editors for Neurodegenerative Diseases?
Topics: DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Superhelical; Humans; Imidazoles; Neurodegenerative Diseases; Nylons; Oligonucleotides; Pyrroles; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topoisomerase Inhibitors | 2022 |
51 other study(ies) available for pyrroles and oligonucleotides
| Article | Year |
|---|---|
Duplex structure formation between oligo(dA)'s and oligo(dT)'s generated by thymine-specific interaction with netropsin.
Topics: Adenine Nucleotides; Anti-Bacterial Agents; Binding Sites; Circular Dichroism; Guanidines; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Polydeoxyribonucleotides; Pyrroles; Temperature; Thymine Nucleotides | 1976 |
Pyrazole analogues of the bispyrrolecarboxamide anti-tumour antibiotics: synthesis, DNA binding and anti-tumour properties.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Base Sequence; DNA, Neoplasm; Leukemia L1210; Leukemia P388; Molecular Sequence Data; Netropsin; Oligonucleotides; Poly dA-dT; Polydeoxyribonucleotides; Pyrroles; Tumor Cells, Cultured | 1991 |
Distamycins inhibit the binding of OTF-1 and NFE-1 transfactors to their conserved DNA elements.
Topics: Base Sequence; Binding, Competitive; Cell Line; Distamycins; DNA-Binding Proteins; Histones; Humans; Leukemia, Erythroblastic, Acute; Oligonucleotides; Pyrroles; Transcription Factors | 1989 |
Distamycin analogues with improved sequence-specific DNA binding activities.
Topics: Amides; Base Sequence; Cell Line, Transformed; Distamycins; DNA; DNA-Binding Proteins; Host Cell Factor C1; Molecular Sequence Data; Octamer Transcription Factor-1; Oligonucleotides; Pyrroles; Transcription Factors | 1994 |
Preparation of a DNA matrix via an electrochemically directed copolymerization of pyrrole and oligonucleotides bearing a pyrrole group.
Topics: Amides; Base Sequence; DNA; Electrochemistry; Electrodes; Genes, ras; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Oligonucleotides; Phosphoric Acids; Polymers; Pyrroles | 1994 |
Polypyrrole DNA chip on a silicon device: example of hepatitis C virus genotyping.
Topics: Biotechnology; DNA; DNA, Viral; Electrochemistry; Genotype; Hepacivirus; Microelectrodes; Nucleic Acid Hybridization; Oligonucleotides; Pyrroles; Quality Control; Sensitivity and Specificity; Silicon | 1998 |
Triple helix formation: binding avidity of acridine-conjugated AG motif third strands containing natural, modified and surrogate bases opposed to pyrimidine interruptions in a polypurine target.
Topics: Acridines; Adenine; Gene Expression Regulation; Genetic Techniques; Guanine; Intercalating Agents; Kinetics; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrimidines; Pyrroles | 1999 |
Conducting polymers on microelectronic devices as tools for biological analyses.
Topics: Immunoassay; Microelectrodes; Microscopy, Fluorescence; Nucleic Acid Hybridization; Oligonucleotides; Polymers; Pyrroles; Reproducibility of Results | 1998 |
Characterization of a duocarmycin-DNA adduct-recognizing protein in cancer cells.
Topics: Animals; Anthramycin; Antibiotics, Antineoplastic; Apoptosis; Binding, Competitive; Cattle; Cell Nucleus; DNA; DNA Adducts; DNA-Binding Proteins; Duocarmycins; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Indoles; Leucomycins; Nuclear Proteins; Oligonucleotides; Pyrroles; Ribonucleoproteins; Thymus Gland; Tumor Cells, Cultured | 1999 |
Study of DNA hybridization on polypyrrole grafted with oligonucleotides by photocurrent spectroscopy.
Topics: Biosensing Techniques; DNA; DNA Probes; Nucleic Acid Hybridization; Oligonucleotides; Polymers; Pyrroles; Spectrum Analysis | 2001 |
Effect of the universal base 3-nitropyrrole on the selectivity of neighboring natural bases.
Topics: Base Pair Mismatch; Base Pairing; Oligonucleotides; Pyrroles | 2001 |
The hybridization-stabilization assay: a solution-based isothermal method for rapid screening and determination of sequence preference of ligands that bind to duplexed nucleic acids.
Topics: Base Pairing; Base Sequence; Binding, Competitive; Dactinomycin; Distamycins; DNA Footprinting; Drug Evaluation, Preclinical; Energy Transfer; Fluorescence; Intercalating Agents; Kinetics; Ligands; Netropsin; Nucleic Acid Hybridization; Nucleic Acids; Nylons; Oligonucleotides; Promoter Regions, Genetic; Pyrroles; Reproducibility of Results; Solutions; Substrate Specificity; Temperature; Thermodynamics | 2001 |
Electrochemical probing of DNA based on oligonucleotide-functionalized polypyrrole.
Topics: Base Sequence; Biosensing Techniques; DNA; Electric Conductivity; Electrochemistry; Molecular Structure; Oligonucleotides; Polymers; Pyrroles; Spectroscopy, Fourier Transform Infrared | 2001 |
Cyclic AMP inhibits stretch-induced overexpression of fibronectin in glomerular mesangial cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Bucladesine; Carbazoles; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Epoprostenol; Fibronectins; Gene Expression Regulation; Glomerular Mesangium; Indoles; Male; Mitogen-Activated Protein Kinases; Nuclear Proteins; Oligonucleotides; Protein Binding; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Transcription Factor AP-1 | 2002 |
Atorvastatin inhibition of cytokine-inducible nitric oxide synthase expression in native endothelial cells in situ.
Topics: Animals; Aorta, Thoracic; Atorvastatin; Cells, Cultured; Cytokines; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Vitro Techniques; Interferon-gamma; Male; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligonucleotides; Pyrroles; Rats; Rats, Wistar; STAT1 Transcription Factor; Trans-Activators; Tumor Necrosis Factor-alpha | 2002 |
Hydration of hydroxypyrrole influences binding of ImHpPyPy-beta-Dp polyamide to DNA.
Topics: Computer Simulation; Crystallography, X-Ray; DNA; Hydrogen Bonding; Nucleic Acid Conformation; Nylons; Oligonucleotides; Polymers; Pyrroles; Water | 2003 |
Molecular design of a pyrrole-imidazole hairpin polyamides for effective DNA alkylation.
Topics: Alkylation; Base Pairing; Base Sequence; Chromatography, High Pressure Liquid; DNA; Drug Design; Imidazoles; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Nylons; Oligonucleotides; Pyrroles; Temperature | 2002 |
Specific alkylation of human telomere repeats by hairpin pyrrole-imidazole polyamide.
Topics: Adenine; Alkylation; Antineoplastic Agents, Alkylating; Cell Division; Cell Line, Tumor; DNA; Humans; Imidazoles; Inhibitory Concentration 50; Nucleic Acid Conformation; Nylons; Oligonucleotides; Pyrroles; Repetitive Sequences, Nucleic Acid; Telomere | 2003 |
Enantioselective DNA alkylation by a pyrrole-imidazole S-CBI conjugate.
Topics: Alkylation; Chromatography, High Pressure Liquid; Cyclopropanes; DNA; Imidazoles; Indoles; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Pyrroles; Stereoisomerism; Thermodynamics | 2004 |
DNA cross-linking by dehydromonocrotaline lacks apparent base sequence preference.
Topics: Amino Acids; Aspartic Acid; Base Sequence; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Indicators and Reagents; Monocrotaline; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Tyrosine | 2004 |
New approach to writing and simultaneous reading of micropatterns: combining surface plasmon resonance imaging with scanning electrochemical microscopy (SECM).
Topics: Gold; Microscopy, Electron, Scanning; Oligonucleotides; Particle Size; Polymers; Pyrroles; Surface Plasmon Resonance; Surface Properties | 2004 |
Analysis of noncovalent complexes between human telomeric DNA and polyamides containing N-methylpyrrole and N-methylimidazole by using electrospray ionization mass spectrometry.
Topics: DNA; Humans; Imidazoles; Molecular Structure; Nylons; Oligonucleotides; Pyrroles; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Telomere | 2005 |
Direct electrochemical sensor for fast reagent-free DNA detection.
Topics: Biosensing Techniques; DNA, Viral; Electrochemistry; Nucleic Acid Hybridization; Oligonucleotides; Polymers; Pyrroles; Variola virus | 2005 |
Synthetic pyrrole-imidazole polyamide inhibits expression of the human transforming growth factor-beta1 gene.
Topics: Blotting, Western; Cells, Cultured; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoretic Mobility Shift Assay; Endothelial Cells; Gene Expression Regulation; Humans; Indicators and Reagents; Nylons; Oligonucleotides; Promoter Regions, Genetic; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tubulin | 2005 |
Duocarmycins binding to DNA investigated by molecular simulation.
Topics: Adenine; Algorithms; Alkylation; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Catalysis; Computer Simulation; DNA; Duocarmycins; Hydrogen Bonding; Indoles; Molecular Conformation; Oligonucleotides; Pyrroles | 2006 |
Investigation of non-covalent complexes of HIV-1 promoter DNA and polyamides containing N-methylpyrrole by electrospray ionization mass spectrometry.
Topics: DNA, Viral; HIV-1; Nylons; Oligonucleotides; Promoter Regions, Genetic; Pyrroles; Spectrometry, Mass, Electrospray Ionization; TATA Box | 2006 |
Programmable oligomers for minor groove DNA recognition.
Topics: Base Pairing; DNA; Nucleic Acid Conformation; Nylons; Oligonucleotides; Protein Binding; Pyrroles | 2006 |
Spin labeling of oligonucleotides with the nitroxide TPA and use of PELDOR, a pulse EPR method, to measure intramolecular distances.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Pyrroles; Spin Labels | 2007 |
DNA immobilization/hybridization on plasma-polymerized pyrrole.
Topics: Adhesiveness; Biosensing Techniques; DNA; Nucleic Acid Hybridization; Oligonucleotides; Pyrroles; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared | 2008 |
Label-free target DNA recognition using oligonucleotide-functionalized polypyrrole nanotubes.
Topics: Breast Neoplasms; DNA, Neoplasm; Female; Genes, Neoplasm; Humans; Microscopy, Confocal; Microscopy, Scanning Probe; Nanotubes; Oligonucleotides; Polymers; Pyrroles | 2008 |
A conjoined thienopyrrole oligomer formed by using DNA as a molecular guide.
Topics: Aniline Compounds; Base Sequence; Cytosine; DNA; Horseradish Peroxidase; Hydrogen Peroxide; Nucleic Acid Hybridization; Oligonucleotides; Polymers; Pyrroles; Spectrophotometry, Ultraviolet | 2008 |
Fluorescence and hybridization properties of peptide nucleic acid containing a substituted phenylpyrrolocytosine designed to engage Guanine with an additional H-bond.
Topics: Cytosine; DNA, Complementary; Fluorescent Dyes; Guanine; Hydrogen Bonding; Models, Molecular; Nucleic Acid Hybridization; Oligonucleotides; Peptide Nucleic Acids; Pyrroles; Quantum Theory; RNA | 2008 |
ESI-MS characterization of a novel pyrrole-inosine nucleoside that interacts with guanine bases.
Topics: Base Composition; Base Sequence; DNA, Single-Stranded; G-Quadruplexes; Guanine; Hydrogen Bonding; Inosine; Ligands; Nucleosides; Oligonucleotides; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2008 |
A new method for the determination of the relative affinity of a ligand against various DNA sequences by electrospray ionization mass spectrometry. Application to a polyamide minor groove binder.
Topics: Binding Sites; Binding, Competitive; DNA; Ligands; Models, Molecular; Nylons; Oligonucleotides; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Solid-phase synthesis of azaphthalocyanine-oligonucleotide conjugates and their evaluation as new dark quenchers of fluorescence.
Topics: Absorption; Base Sequence; Chromatography, High Pressure Liquid; Fluorescent Dyes; Oligonucleotide Probes; Oligonucleotides; Pyrazines; Pyrroles; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Versatile functionalization of nanoelectrodes by oligonucleotides via pyrrole electrochemistry.
Topics: Base Sequence; Electrochemical Techniques; Microelectrodes; Microscopy, Atomic Force; Nanotechnology; Oligonucleotides; Polymers; Pyrroles | 2010 |
Effect of base sequence on the DNA cross-linking properties of pyrrolobenzodiazepine (PBD) dimers.
Topics: Base Sequence; Benzodiazepines; Benzodiazepinones; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dimerization; DNA; Mass Spectrometry; Models, Molecular; Oligonucleotides; Pyrroles | 2011 |
Synthesis of β-pyrrolic-modified porphyrins and their incorporation into DNA.
Topics: Base Sequence; Catalysis; Click Chemistry; Cyclization; DNA; DNA, Single-Stranded; Intercalating Agents; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Palladium; Porphyrins; Pyrimidines; Pyrroles; Temperature | 2011 |
Development of a novel gene silencer pyrrole-imidazole polyamide targeting human connective tissue growth factor.
Topics: Cells, Cultured; Connective Tissue Growth Factor; DNA; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrophoretic Mobility Shift Assay; Fluorescein-5-isothiocyanate; Gene Expression Regulation; Gene Silencing; Gene Targeting; Genetic Therapy; Glycosphingolipids; Humans; Imidazoles; Mesangial Cells; Molecular Targeted Therapy; Neoplasms, Fibrous Tissue; Nylons; Oligonucleotides; Phorbols; Promoter Regions, Genetic; Pyrroles; Transforming Growth Factor beta1 | 2011 |
Use of a multiplexed CMOS microarray to optimize and compare oligonucleotide binding to DNA probes synthesized or immobilized on individual electrodes.
Topics: Biosensing Techniques; Carbocyanines; DNA Probes; Electrodes; Fluorescence; Horseradish Peroxidase; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Polymers; Pyrroles; Sequence Analysis, DNA | 2010 |
High-capacity conductive nanocellulose paper sheets for electrochemically controlled extraction of DNA oligomers.
Topics: Buffers; Cellulose; DNA; Electric Conductivity; Electrochemical Techniques; Electrodes; Nanostructures; Oligonucleotides; Paper; Polymers; Pyrroles; Solutions; Spectrometry, Fluorescence; Time Factors | 2011 |
High-performance capillary electrophoretic separation of double-stranded oligonucleotides using a poly-(ethylpyrrolidine methacrylate-co-methylmethacrylate)-coated capillary.
Topics: Electrophoresis, Capillary; Oligonucleotides; Polymethacrylic Acids; Pyrroles; Reproducibility of Results; Temperature | 2012 |
Mod5 protein binds to tRNA gene complexes and affects local transcriptional silencing.
Topics: Alkyl and Aryl Transferases; Arabidopsis; Atorvastatin; Blotting, Northern; Cell Nucleolus; Chromatin Immunoprecipitation; Cloning, Molecular; DNA Primers; Gene Silencing; Heptanoic Acids; Humans; Immunoprecipitation; In Situ Hybridization; Oligonucleotides; Promoter Regions, Genetic; Pyrroles; RNA Polymerase II; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension.
Topics: Animals; Hypertension, Pulmonary; Hypoxia; Indoles; Lipids; Liposomes; Lung; Male; MicroRNAs; Nanoparticles; Oligonucleotides; Pyrroles; Rats, Sprague-Dawley | 2015 |
High Affinity Pharmacological Profiling of Dual Inhibitors Targeting RET and VEGFR2 in Inhibition of Kinase and Angiogeneis Events in Medullary Thyroid Carcinoma.
Topics: Angiogenesis Inhibitors; Anilides; Carcinoma, Neuroendocrine; Databases, Chemical; Drug Discovery; Humans; Imidazoles; Indoles; Molecular Docking Simulation; Molecular Structure; Niacinamide; Oligonucleotides; Piperidines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sunitinib; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA.
Topics: Anthramycin; Base Sequence; Benzodiazepines; Binding Sites; Deoxyribonuclease I; DNA; DNA Footprinting; Guanine; Molecular Dynamics Simulation; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Spectrometry, Fluorescence; Temperature | 2017 |
Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink.
Topics: Base Pairing; Base Sequence; Benzodiazepinones; Cell Cycle Proteins; Cloning, Molecular; Cross-Linking Reagents; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Escherichia coli; Exodeoxyribonucleases; Gene Expression; Humans; Nucleic Acid Conformation; Oligonucleotides; Plasmids; Pyrroles; Recombinant Proteins; Saccharomyces cerevisiae | 2018 |
Antibody-Drug Conjugates with Indolinobenzodiazepine Dimer Payloads: DNA-Binding Mechanism of Indolinobenzodiazepine Dimer Catabolites in Target Cancer Cells.
Topics: Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Dimerization; DNA; DNA Adducts; Enzyme-Linked Immunospot Assay; Humans; Imines; Immunoconjugates; Indoles; Oligonucleotides; Pyrroles | 2020 |
Rapid and label-free electrochemical DNA biosensor based on a facile one-step electrochemical synthesis of rGO-PPy-(L-Cys)-AuNPs nanocomposite for the HTLV-1 oligonucleotide detection.
Topics: Biosensing Techniques; Cysteine; DNA; Electrochemical Techniques; Gold; Graphite; Human T-lymphotropic virus 1; Humans; Metal Nanoparticles; Molecular Structure; Nanocomposites; Oligonucleotides; Particle Size; Polymers; Pyrroles; Surface Properties | 2021 |
DNA with Purine-Purine Base Pairs: Size and Position of Isoguanine and 8-Aza-7-deazaisoguanine Clickable Residues Control the Molecular Recognition of Guanine and 5-Aza-7-deazaguanine.
Topics: Base Pairing; DNA; Guanine; Nucleic Acid Conformation; Oligonucleotides; Purines; Pyrenes; Pyrimidines; Pyrroles | 2022 |
Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.
Topics: DNA; Netropsin; Nucleic Acid Conformation; Nylons; Oligonucleotides; Pyrroles | 2023 |