Page last updated: 2024-08-18

pyrroles and norleucine

pyrroles has been researched along with norleucine in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.47)18.7374
1990's25 (36.76)18.2507
2000's18 (26.47)29.6817
2010's19 (27.94)24.3611
2020's5 (7.35)2.80

Authors

AuthorsStudies
Chen, TM; Coutant, JE1
Monnier, VM; Nagaraj, RH; Portero-Otin, M2
Igaki, N; Kasuga, M; Miyata, S; Miyauchi, Y; Ohara, T; Oimomi, M; Sakai, M; Shoda, H; Yamada, H; Yatabe, H1
Carlson, EC; Marion, MS1
Miyata, S; Monnier, VM; Perry, G; Richey, PL; Sayre, LM; Smith, MA; Stern, D; Taneda, S; Yan, SD1
Benn, J; Smith, PR; Somani, HH; Sonksen, PH; Thornalley, PJ1
Nagaraj, RH; Sady, C1
Amano, I; Iwayama, N; Maeda, K; Matsumoto, Y; Miwa, M; Nakai, S; Odani, H; Shinzato, T; Takai, I1
Bachmann, A; Henle, T1
Castellani, R; Perry, G; Richey, PL; Smith, MA1
Bellmunt, MJ; Bergua, M; Nagaraj, RH; Pamplona, R; Portero-Otín, M; Prat, J1
Kasuga, M; Liu, BF; Miyata, S; Ohara, T; Shoda, H; Suzuki, K; Yamada, H1
Bailey, AJ; Paul, RG1
Elgawish, AH; Friedlander, MA; Glomb, M; Monnier, VM; Nagaraj, RH; Portero-Otin, M; Sell, DR1
Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV1
Horie, K; Iida, Y; Maeda, K; Miyata, T; Sugiyama, S; Tanaka, H; Tsuyuki, M1
Kasuga, M; Liu, BF; Miyata, S; Ohara, T; Oimomi, M; Shoda, H; Suzuki, K; Yamada, H1
Castellani, RJ; Cohen, ML; Harris, PL; Monnier, VM; Perry, G; Smith, MA1
Bellmunt, MJ; Bergua, M; Pamplona, R; Portero-Otín, M; Prat, J1
Deyl, Z; Miksík, I1
Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL1
Block, C; Ferguson, K; Fogarty, J; Haas, C; Hampel, N; Ni, Z; Polak, J; Razmjouei, K; Seftel, AD; Vaziri, ND; Wang, RZ1
Angelini, G; Dagna-Bricarelli, F; Dapino, D; Garibaldi, S; Odetti, P; Perry, G; Piombo, G; Smith, M; Tabaton, M; Traverso, N; Zaccheo, D1
Beck, W; Deppisch, R; Hänsch, GM; Henle, T; Hergesell, O; Ritz, E1
Kasuga, M; Kojima, H; Kusunoki, H; Liu, BF; Miyata, S; Suzuki, K; Uriuhara, A1
Angelini, G; Garibaldi, S; Marinelli, L; Menini, S; Norese, R; Odetti, P; Perry, G; Siedlak, S; Smith, MA; Tabaton, M; Traverso, N; Valentini, S; Zaccheo, D1
Cleveland, DW; Hirano, A; Horiuchi, S; Kato, M; Kato, S; Liu, J; Nagai, R; Nakano, I; Nakashima, K; Ohama, E; Shibata, N; Takikawa, M1
Amano, S; Horiuchi, S; Kaji, Y; Machinami, R; Nagai, R; Oka, T; Oshika, T1
Alaiz, M; Hidalgo, FJ; Zamora, R1
Beppu, M; Kiyonami, R; Shimizu, Y; Yoshihara, K1
Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M1
Daimon, M; Hirata, A; Igarashi, M; Kameda, W; Kato, T; Ohnuma, H; Oizumi, T; Saitoh, T; Sugiyama, K; Yamaguchi, H1
Beppu, M; Hata, I; Hiraoka, M; Kaji, M; Kawakami, H; Mayumi, M; Momoi, T; Sekine, K; Todoroki, Y; Tsukahara, H; Uchiyama, M; Yorifuji, T; Yoshihara, K1
Foerster, A; Henle, T1
Hiraoka, M; Ito, S; Mayumi, M; Noiri, E; Ohta, N; Sato, S; Shibata, R; Tsukahara, H1
Aizawa, K; Hirano, K; Inakuma, T; Kiho, T; Usui, S1
Leal, LI; Méndez, JD1
Ahmed, N; Horiuchi, S; Jono, T; Lin, X; Nagai, R; Takeya, M; Thornalley, PJ1
Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T1
Anraku, M; Kitamura, K; Maruyama, T; Mera, K; Nakajou, K; Otagiri, M; Tomita, K1
Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP1
Ahmad, W; Deng, Y; Li, L1
Brandsch, M; Geissler, S; Hellwig, M; Henle, T; Knütter, I; Peto, A1
Brandsch, M; Geissler, S; Hellwig, M; Henle, T; Markwardt, F; Zwarg, M1
Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J1
Heilmann, M; Ilchmann, A; Toda, M; Vieths, S1
Brimble, MA; Cooper, GJ; Woods, TM1
Briza, P; Burgdorf, S; Gadermaier, G; Heilmann, M; Henle, T; Ilchmann, A; Krause, M; Nagai, R; Scheurer, S; Toda, M; Vieths, S; Wellner, A1
Andrade, V; Batoréu, MC; dos Santos, AP; Gonçalves, LL; Mateus, ML; Torres, ME1
Brimble, MA; Harris, PW; Kamalov, M; Wood, JM1
Brandolini, A; Cattaneo, S; De Noni, I; Hidalgo, A; Masotti, F; Stuknytė, M1
Bunzel, D; Franz, CM; Hellwig, M; Henle, T; Huch, M; Kulling, SE1
Fu, Q; Li, B; Li, L; Liang, Z; Xu, Z; Zhang, X1
Cai, P; Li, B; Li, L; Liang, Z; Qi, H; Wan, L; Xu, Z1
Li, B; Li, L; Liang, Z; Qi, H; Xu, Z; Zhang, X1
Hellwig, M; Henle, T; Witte, S1
Li, B; Li, L; Liang, Z; Qi, H; Zhang, ZX1
Beer, F; Börner, M; Hellwig, M; Henle, T; van Pée, KH1
Chen, X; Liu, H; Mu, L; Sun, B; Wang, J; Wang, S1
Fiedler, R; Gebert, M; Girndt, M; Glomb, MA; Henning, C; Hohmann, C; Hulko, M; Liehr, K; Storr, M1
Li, H; Yu, SJ1
Chen, X; Lai, Y; Lei, C; Liang, Z; Yang, Y; Yang, Z; Zeng, Y1
Cattaneo, S; De Noni, I; Mallardi, D; Masotti, F; Pica, V; Roggero, P; Stuknytė, M; Tabasso, C1
Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q1
Li, B; Li, L; Qi, H; Zhang, X; Zhang, Z1
Beniddir, MA; Fontaine, V; Fouotsa, H; Gallard, JF; Lannang, AM; Le Pogam, P; Leblanc, K; Meyer, F; Mkounga, P; Nkengfack, AE; Poupon, E; Rharrabti, S; Vanheuverzwijn, J; Zhou, Z1
Banerjee, S1

Reviews

8 review(s) available for pyrroles and norleucine

ArticleYear
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
Structure of advanced Maillard reaction products and their pathological role.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lens, Crystalline; Maillard Reaction; Molecular Structure; Norleucine; Peritoneal Dialysis; Pyrroles; Renal Dialysis

1996
New biomarkers of Maillard reaction damage to proteins.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles

1996
Advanced glycation end-products in diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Animals; Arginine; Blood Glucose; Diabetic Nephropathies; Glycation End Products, Advanced; Glycosylation; Humans; Immunohistochemistry; Lysine; Norleucine; Proteins; Pyrroles

1996
Post-translational non-enzymatic modification of proteins. I. Chromatography of marker adducts with special emphasis to glycation reactions.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Oct-10, Volume: 699, Issue:1-2

    Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Glycosylation; Imidazoles; Lysine; Malondialdehyde; Mass Spectrometry; Norleucine; Protein Processing, Post-Translational; Proteins; Pyrroles

1997
Glycation in food and metabolic transit of dietary AGEs (advanced glycation end-products): studies on the urinary excretion of pyrraline.
    Biochemical Society transactions, 2003, Volume: 31, Issue:Pt 6

    Topics: Adult; Chromatography, High Pressure Liquid; Diet; Female; Glycation End Products, Advanced; Humans; Male; Middle Aged; Norleucine; Pyrroles; Spectrophotometry, Ultraviolet

2003
The Maillard reaction and food allergies: is there a link?
    Clinical chemistry and laboratory medicine, 2014, Jan-01, Volume: 52, Issue:1

    Topics: Arginine; Dendritic Cells; Food Hypersensitivity; Glycation End Products, Advanced; Humans; Immunoglobulin E; Lysine; Maillard Reaction; Norleucine; Pyrroles; Receptors, Scavenger; T-Lymphocytes

2014
Review of pentosidine and pyrraline in food and chemical models: formation, potential risks and determination.
    Journal of the science of food and agriculture, 2018, Volume: 98, Issue:9

    Topics: Arginine; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Food Analysis; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Lysine; Molecular Structure; Norleucine; Pyrroles; Risk Factors; Uremia

2018

Trials

2 trial(s) available for pyrroles and norleucine

ArticleYear
Determination of urinary pyrraline by solid-phase extraction and high performance liquid chromatography.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:8

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Humans; Mass Spectrometry; Middle Aged; Norleucine; Pyrroles

2001
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde

2003

Other Studies

58 other study(ies) available for pyrroles and norleucine

ArticleYear
Thermospray high-performance liquid chromatographic-mass spectrometric characterization of biological macromolecules. I. Analysis of acid hydrolysate of peptides.
    Journal of chromatography, 1989, Jan-20, Volume: 463, Issue:1

    Topics: Amino Acids; Aminocaproates; Chromatography, High Pressure Liquid; Hydrolysis; Maillard Reaction; Mass Spectrometry; Norleucine; Peptides; Pyrroles

1989
Chromatographic evidence for pyrraline formation during protein glycation in vitro and in vivo.
    Biochimica et biophysica acta, 1995, Feb-22, Volume: 1247, Issue:1

    Topics: Animals; Blood Proteins; Cattle; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Glucose; Glycosylation; Humans; Magnetic Resonance Spectroscopy; Norleucine; Pyrroles; Serum Albumin, Bovine

1995
Increase in 3-deoxyglucosone levels in diabetic rat plasma. Specific in vivo determination of intermediate in advanced Maillard reaction.
    The Journal of biological chemistry, 1994, Aug-12, Volume: 269, Issue:32

    Topics: 2-Naphthylamine; Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Male; Norleucine; Pyrroles; Rats; Rats, Wistar; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet

1994
Immunoelectron microscopic analyses of Maillard reaction products in bovine anterior lens capsule and Descemet's membrane.
    Biochimica et biophysica acta, 1994, Apr-20, Volume: 1191, Issue:1

    Topics: Aging; Animals; Basement Membrane; Carbohydrates; Cattle; Descemet Membrane; In Vitro Techniques; Lens Capsule, Crystalline; Maillard Reaction; Microscopy, Immunoelectron; Norleucine; Pyrroles

1994
Advanced Maillard reaction end products are associated with Alzheimer disease pathology.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jun-07, Volume: 91, Issue:12

    Topics: Alzheimer Disease; Arginine; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Lysine; Maillard Reaction; Neurofibrillary Tangles; Norleucine; Pyrroles

1994
Evidence against the formation of 2-amino-6-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-hexanoic acid ('pyrraline') as an early-stage product or advanced glycation end product in non-enzymic protein glycation.
    Clinical science (London, England : 1979), 1993, Volume: 84, Issue:1

    Topics: Animals; Blood Proteins; Blotting, Western; Cattle; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Fructosamine; Glucose; Glycation End Products, Advanced; Hexosamines; Humans; In Vitro Techniques; Maillard Reaction; Norleucine; Pyrroles; Serum Albumin, Bovine

1993
Pyrraline ether crosslinks as a basis for protein crosslinking by the advanced Maillard reaction in aging and diabetes.
    Archives of biochemistry and biophysics, 1996, Jan-15, Volume: 325, Issue:2

    Topics: Aging; Amino Acids; Animals; Cross-Linking Reagents; Diabetes Mellitus; Ethers; Humans; Magnetic Resonance Spectroscopy; Maillard Reaction; Molecular Structure; Norleucine; Proteins; Pyrroles; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry

1996
The presence of a glucose-derived Maillard reaction product in the human lens.
    FEBS letters, 1996, Mar-18, Volume: 382, Issue:3

    Topics: Animals; Cataract; Cattle; Crystallins; Deoxyglucose; Diabetes Mellitus; Humans; Lens, Crystalline; Maillard Reaction; Norleucine; Protein Conformation; Pyrroles

1996
First evidence for accumulation of protein-bound and protein-free pyrraline in human uremic plasma by mass spectrometry.
    Biochemical and biophysical research communications, 1996, Jul-05, Volume: 224, Issue:1

    Topics: Blood Proteins; Humans; Kidney Failure, Chronic; Mass Spectrometry; Middle Aged; Norleucine; Protein Binding; Pyrroles; Reference Values; Renal Dialysis; Uremia

1996
Synthesis of pyrraline reference material.
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1996, Volume: 202, Issue:1

    Topics: Cooking; Food Analysis; Hot Temperature; Indicators and Reagents; Maillard Reaction; Molecular Structure; Norleucine; Pyrroles; Reference Standards

1996
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
    Brain research, 1996, Oct-21, Volume: 737, Issue:1-2

    Topics: Aged; Aged, 80 and over; Arginine; Cerebral Cortex; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Heme Oxygenase (Decyclizing); Humans; Immunohistochemistry; Locus Coeruleus; Lysine; Microscopy, Immunoelectron; Middle Aged; Neurons; Norleucine; Oxidative Stress; Parkinson Disease; Pyrroles; Substantia Nigra

1996
Urinary pyrraline as a biochemical marker of non-oxidative Maillard reactions in vivo.
    Life sciences, 1997, Volume: 60, Issue:4-5

    Topics: Adolescent; Adult; Biomarkers; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 1; Female; Humans; Hydrolysis; Maillard Reaction; Male; Mass Spectrometry; Norleucine; Pyrroles; Reference Standards; Spectrophotometry, Ultraviolet

1997
Accumulation of pyrraline-modified albumin in phagocytes due to reduced degradation by lysosomal enzymes.
    The Journal of biological chemistry, 1997, Feb-14, Volume: 272, Issue:7

    Topics: Albumins; Animals; Cathepsin D; Humans; Hydrolysis; Lysosomes; Mice; Norleucine; Phagocytes; Pyrroles; Rats

1997
Inhibitory effects of tenilsetam on the Maillard reaction.
    Endocrinology, 1997, Volume: 138, Issue:5

    Topics: Animals; Aorta; Blood Glucose; Collagen; Deoxyglucose; Diabetes Mellitus, Experimental; Fructose; Glucose; Glycated Hemoglobin; Kidney Cortex; Macromolecular Substances; Maillard Reaction; Male; Muramidase; Norleucine; Piperazines; Psychotropic Drugs; Pyrroles; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Thiophenes

1997
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease.
    Neuroscience letters, 1997, Aug-08, Volume: 231, Issue:2

    Topics: Adolescent; Arginine; Astrocytes; Brain Diseases; Child; Cross-Linking Reagents; Crystallins; Demyelinating Diseases; Glycation End Products, Advanced; Humans; Inclusion Bodies; Lysine; Norleucine; Pyrroles

1997
Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients.
    European journal of clinical investigation, 1997, Volume: 27, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Child; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 1; Female; Fructosamine; Glycated Hemoglobin; Humans; Maillard Reaction; Male; Matched-Pair Analysis; Middle Aged; Norleucine; Pyrroles; Regression Analysis; Urea

1997
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
    The Journal of clinical investigation, 1997, Dec-15, Volume: 100, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits

1997
Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS.
    Urology, 1997, Volume: 50, Issue:6

    Topics: Adult; Aged; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Electron Probe Microanalysis; Endothelium; Enzyme Induction; Erectile Dysfunction; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norleucine; Penis; Pyrroles

1997
Early glycoxidation damage in brains from Down's syndrome.
    Biochemical and biophysical research communications, 1998, Feb-24, Volume: 243, Issue:3

    Topics: Aldehydes; Amyloid beta-Protein Precursor; Arginine; Brain; Cerebral Cortex; Down Syndrome; Gestational Age; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lysine; Norleucine; Oxidation-Reduction; Oxidative Stress; Pyrroles; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

1998
Advanced glycated end-products (AGE) during haemodialysis treatment: discrepant results with different methodologies reflecting the heterogeneity of AGE compounds.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:8

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Female; Fluorescence; Glycation End Products, Advanced; Hemofiltration; Humans; Lysine; Male; Middle Aged; Molecular Weight; Norleucine; Pyrroles; Renal Dialysis

1999
Low phagocytic activity of resident peritoneal macrophages in diabetic mice: relevance to the formation of advanced glycation end products.
    Diabetes, 1999, Volume: 48, Issue:10

    Topics: Adenosine Triphosphate; Animals; Cattle; Cell Separation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Flow Cytometry; Glycation End Products, Advanced; Indoles; Macrophages, Peritoneal; Maleimides; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Norleucine; Phagocytosis; Protein Kinase C; Pyrroles

1999
Lipoperoxidation is selectively involved in progressive supranuclear palsy.
    Journal of neuropathology and experimental neurology, 2000, Volume: 59, Issue:5

    Topics: Aged; Aldehydes; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxides; Lysine; Mesencephalon; Middle Aged; Norleucine; Pyrroles; Reference Values; Supranuclear Palsy, Progressive; tau Proteins; Thiobarbituric Acid Reactive Substances

2000
Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation.
    Acta neuropathologica, 2000, Volume: 100, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Animals; Arginine; Female; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Inclusion Bodies; Lysine; Male; Mice; Mice, Transgenic; Microscopy, Electron; Microscopy, Immunoelectron; Middle Aged; Mutation; Norleucine; Pyrroles; Superoxide Dismutase; Superoxide Dismutase-1

2000
Advanced glycation end products in human optic nerve head.
    The British journal of ophthalmology, 2001, Volume: 85, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Ethmoid Bone; Female; Glycosylation; Humans; Immunoenzyme Techniques; Male; Middle Aged; Norleucine; Optic Disk; Pia Mater; Pyrroles; Retinal Vessels; Sclera

2001
Pyrrolization and antioxidant function of proteins following oxidative stress.
    Chemical research in toxicology, 2001, Volume: 14, Issue:5

    Topics: Animals; Antioxidants; Electrophoresis, Capillary; Lipid Peroxidation; Microsomes; Muscles; Norleucine; Oxidative Stress; Proteins; Pyrroles; Reactive Oxygen Species; Serum Albumin, Bovine; Thiobarbituric Acid Reactive Substances; Trout

2001
Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes.
    Endocrine journal, 2003, Volume: 50, Issue:1

    Topics: Acrolein; Adult; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Norleucine; Pyrroles; Smoking

2003
Formation of advanced glycosylation end products and oxidative stress in young patients with type 1 diabetes.
    Pediatric research, 2003, Volume: 54, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrolein; Adolescent; Adult; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Diabetes Mellitus, Type 1; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles; Regression Analysis

2003
High levels of urinary pentosidine, an advanced glycation end product, in children with acute exacerbation of atopic dermatitis: relationship with oxidative stress.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Arginine; Child; Child, Preschool; Creatinine; Deoxyguanosine; Dermatitis, Atopic; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Norleucine; Oxidative Stress; Pyrroles

2003
Tomato paste fraction inhibiting the formation of advanced glycation end-products.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:1

    Topics: Arginine; Blotting, Western; Chemical Fractionation; Enzyme-Linked Immunosorbent Assay; Food; Glucose; Glycation End Products, Advanced; Lysine; Molecular Weight; Nitroblue Tetrazolium; Norleucine; Oxidation-Reduction; Pyrroles; Rutin; Serum Albumin, Bovine; Solanum lycopersicum; Spectrometry, Fluorescence

2004
Inhibition of in vitro pyrraline formation by L-arginine and polyamines.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2004, Volume: 58, Issue:10

    Topics: Animals; Arginine; Cadaverine; Cattle; Dose-Response Relationship, Drug; Glucose; Glycation End Products, Advanced; Norleucine; Polyamines; Putrescine; Pyrroles; Serum Albumin, Bovine; Spermidine; Spermine

2004
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
    Journal of biochemistry, 2004, Volume: 136, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors

2004
Immunohistochemical localization of advanced glycation end products in pinguecula.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles

2006
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Proteins; Case-Control Studies; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Neutrophils; Norleucine; Oxidative Stress; Protein Carbonylation; Pyrroles; Renal Dialysis; Respiratory Burst; Serum Albumin

2005
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin

2008
Identification of AGE-precursors and AGE formation in glycation-induced BSA peptides.
    BMB reports, 2008, Jul-31, Volume: 41, Issue:7

    Topics: Amino Acid Sequence; Glycation End Products, Advanced; Glycolipids; Glycosides; Glycosylation; Imidazoles; Lysine; Models, Biological; Norleucine; Pyrroles; Schiff Bases; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization

2008
Transport of free and peptide-bound pyrraline at intestinal and renal epithelial cells.
    Journal of agricultural and food chemistry, 2009, Jul-22, Volume: 57, Issue:14

    Topics: Alanine; Amino Acid Transport Systems; Animals; Biological Transport; Caco-2 Cells; Cell Line; Dipeptides; Epithelial Cells; Humans; Intestinal Mucosa; Kidney; Kidney Tubules, Proximal; Lysine; Norleucine; Opossums; Peptides; Pyrroles; Rats

2009
Transport of the advanced glycation end products alanylpyrraline and pyrralylalanine by the human proton-coupled peptide transporter hPEPT1.
    Journal of agricultural and food chemistry, 2010, Feb-24, Volume: 58, Issue:4

    Topics: Alanine; Animals; Biological Transport; Dipeptides; DNA, Complementary; Genetic Vectors; Glycation End Products, Advanced; HeLa Cells; Humans; Intestinal Mucosa; Magnetic Resonance Spectroscopy; Maillard Reaction; Norleucine; Oocytes; Peptide Transporter 1; Pyrroles; Restriction Mapping; Symporters; Transfection; Xenopus laevis

2010
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
    Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2

    Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels

2013
Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts.
    Amino acids, 2013, Volume: 45, Issue:2

    Topics: Diabetes Mellitus; Glycation End Products, Advanced; Isotope Labeling; Lysine; Mass Spectrometry; Norleucine; Pyrroles

2013
Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity.
    The Journal of biological chemistry, 2014, Mar-14, Volume: 289, Issue:11

    Topics: Allergens; Animals; Bone Marrow Cells; Carbohydrates; CD4-Positive T-Lymphocytes; Coculture Techniques; Cytokines; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Female; Food Hypersensitivity; Lymphocyte Activation; Maillard Reaction; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Norleucine; Ovalbumin; Protein Structure, Secondary; Pyrroles; Receptors, Scavenger

2014
Role of N-acetylcysteine in protecting against 2,5-hexanedione neurotoxicity in a rat model: changes in urinary pyrroles levels and motor activity performance.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:3

    Topics: Acetylcysteine; Animals; Chromatography, Liquid; Hexanones; Male; Motor Activity; Neuroprotective Agents; Neurotoxins; Norleucine; Pyrroles; Rats; Rats, Wistar; Tandem Mass Spectrometry

2014
On resin synthesis and cross-linking of collagen peptides containing the advanced glycation end-product pyrraline via Maillard condensation.
    Chemical communications (Cambridge, England), 2015, Jun-11, Volume: 51, Issue:46

    Topics: Collagen; Glycation End Products, Advanced; Norleucine; Peptides; Polystyrenes; Pyrroles

2015
Heat damage and in vitro starch digestibility of puffed wheat kernels.
    Food chemistry, 2015, Dec-01, Volume: 188

    Topics: Antioxidants; Chemical Phenomena; Edible Grain; Food Handling; Furaldehyde; Glucose; Hot Temperature; Hydrolysis; Maillard Reaction; Maltose; Models, Biological; Norleucine; Pyrroles; Starch; Trisaccharides; Triticum

2015
Stability of Individual Maillard Reaction Products in the Presence of the Human Colonic Microbiota.
    Journal of agricultural and food chemistry, 2015, Aug-05, Volume: 63, Issue:30

    Topics: Adult; Bacteria; Colon; Female; Gastrointestinal Microbiome; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Norleucine; Pyridones; Pyrroles

2015
Formation and elimination of pyrraline in the Maillard reaction in a saccharide-lysine model system.
    Journal of the science of food and agriculture, 2016, Volume: 96, Issue:7

    Topics: Carbohydrates; Hot Temperature; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Pyrroles; Time Factors

2016
Formation of Peptide Bound Pyrraline in the Maillard Model Systems with Different Lys-Containing Dipeptides and Tripeptides.
    Molecules (Basel, Switzerland), 2016, Apr-07, Volume: 21, Issue:4

    Topics: Amino Acid Sequence; Amino Acids; Dipeptides; Glucose; Glycation End Products, Advanced; Maillard Reaction; Models, Molecular; Norleucine; Peptide Fragments; Peptides; Protein Binding; Pyrroles; Quantitative Structure-Activity Relationship

2016
Determination of Free-Form and Peptide Bound Pyrraline in the Commercial Drinks Enriched with Different Protein Hydrolysates.
    International journal of molecular sciences, 2016, Jul-04, Volume: 17, Issue:7

    Topics: Beverages; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Norleucine; Peptides; Pyrroles; Solid Phase Extraction; Tandem Mass Spectrometry

2016
Free and Protein-Bound Maillard Reaction Products in Beer: Method Development and a Survey of Different Beer Types.
    Journal of agricultural and food chemistry, 2016, Sep-28, Volume: 64, Issue:38

    Topics: Amino Acids; Beer; Food Handling; Lysine; Maillard Reaction; Norleucine; Ornithine; Pyridones; Pyrimidines; Pyrroles; Tandem Mass Spectrometry

2016
Kinetic Study on Peptide-Bound Pyrraline Formation and Elimination in the Maillard Reaction Using Single- and Multiple-Response Models.
    Journal of food science, 2016, Volume: 81, Issue:10

    Topics: Cooking; Dipeptides; Fructose; Glucose; Glycation End Products, Advanced; Hot Temperature; Humans; Kinetics; Maillard Reaction; Mannose; Microwaves; Models, Chemical; Norleucine; Peptides; Pyrroles

2016
Transformation of Free and Dipeptide-Bound Glycated Amino Acids by Two Strains of Saccharomyces cerevisiae.
    Chembiochem : a European journal of chemical biology, 2017, 02-01, Volume: 18, Issue:3

    Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dipeptides; Glycosylation; Maillard Reaction; Norleucine; Protein Stability; Pyridones; Pyrroles; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Tandem Mass Spectrometry

2017
Core-Shell Metal-Organic Frameworks/Molecularly Imprinted Nanoparticles as Absorbents for the Detection of Pyrraline in Milk and Milk Powder.
    Journal of agricultural and food chemistry, 2017, Feb-01, Volume: 65, Issue:4

    Topics: Adsorption; Animals; Cattle; Food Contamination; Limit of Detection; Milk; Molecular Imprinting; Nanoparticles; Norleucine; Polymers; Powders; Pyrroles; Solid Phase Extraction

2017
Detection of Free Advanced Glycation End Products in Vivo during Hemodialysis.
    Journal of agricultural and food chemistry, 2017, Feb-01, Volume: 65, Issue:4

    Topics: Chromatography, Liquid; Female; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Male; Middle Aged; Norleucine; Pyrroles; Renal Dialysis; Tandem Mass Spectrometry

2017
Pyrraline Formation Modulated by Sodium Chloride and Controlled by Encapsulation with Different Coating Materials in the Maillard Reaction.
    Biomolecules, 2019, 11-10, Volume: 9, Issue:11

    Topics: Amylose; Deoxyglucose; Glucose; Glycation End Products, Advanced; Hot Temperature; Lysine; Maillard Reaction; Norleucine; Pyrroles; Sodium Chloride; Zea mays

2019
Effect of protein fortification on heat damage and occurrence of β-casomorphins in (un)digested donor human milk intended for nutrition of preterm infants.
    Food chemistry, 2020, Jun-01, Volume: 314

    Topics: Animals; Cattle; Digestion; Endorphins; Female; Food, Fortified; Hot Temperature; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Lysine; Lysinoalanine; Milk Proteins; Milk, Human; Norleucine; Pasteurization; Pyrroles

2020
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
    Food chemistry, 2020, Jul-01, Volume: 317

    Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde

2020
Two Dipeptide-Bound Pyrralines with Ile or Ala: A Study on Their Synthesis, Transport across Caco-2 Cell Monolayers, and Interaction with Aminopeptidase N.
    Journal of agricultural and food chemistry, 2021, Sep-22, Volume: 69, Issue:37

    Topics: Biological Transport; Caco-2 Cells; CD13 Antigens; Dipeptides; Humans; Norleucine; Pyrroles

2021
Pyrrovobasine, hybrid alkylated pyrraline monoterpene indole alkaloid pseudodimer discovered using a combination of mass spectral and NMR-based machine learning annotations.
    Organic & biomolecular chemistry, 2021, 12-22, Volume: 20, Issue:1

    Topics: Alkylation; Indole Alkaloids; Machine Learning; Magnetic Resonance Spectroscopy; Mass Spectrometry; Monoterpenes; Norleucine; Pyrroles; Voacanga

2021
Biophysical and mass spectrometry based characterization of methylglyoxal-modified myoglobin: Role of advanced glycation end products in inducing protein structural alterations.
    International journal of biological macromolecules, 2021, Dec-15, Volume: 193, Issue:Pt B

    Topics: Glycation End Products, Advanced; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Myoglobin; Norleucine; Protein Conformation, alpha-Helical; Protein Structure, Tertiary; Pyrroles; Pyruvaldehyde

2021